pS23 program activity among Stromal cells

Activation of pS23
pS23 gene program activation in Stromal cells.
Gene program activation of pS23 by different cell subtypes
pS23 gene program activation among cells of different subtypes (Stromal cells).

pS23 top program genes

Top genes of pS23 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pS23 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pS23
pS23 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0051179 localization 0.000434199235774503 6901 132 80 0.606060606060606 0.0115925228227793
GO:BP GO:1902414 protein localization to cell junction 0.000656954289753407 113 108 8 0.0740740740740741 0.0707964601769911
GO:BP GO:0006810 transport 0.00445636662361984 5224 132 62 0.46969696969697 0.0118683001531394
GO:BP GO:0035418 protein localization to synapse 0.00445636662361984 83 108 6 0.0555555555555556 0.072289156626506
GO:BP GO:0001945 lymph vessel development 0.00445636662361984 27 79 4 0.0506329113924051 0.148148148148148
GO:BP GO:0065008 regulation of biological quality 0.00445636662361984 4131 120 49 0.408333333333333 0.0118615347373517
GO:BP GO:0051234 establishment of localization 0.00445636662361984 5372 132 63 0.477272727272727 0.0117274758004468
GO:BP GO:0032879 regulation of localization 0.00445636662361984 2872 132 41 0.310606060606061 0.0142757660167131
GO:BP GO:0071347 cellular response to interleukin-1 0.00799592513722361 185 6 3 0.5 0.0162162162162162
GO:BP GO:0070555 response to interleukin-1 0.0112790492721813 215 6 3 0.5 0.013953488372093
GO:BP GO:1901700 response to oxygen-containing compound 0.0117361793104147 1739 131 28 0.213740458015267 0.0161012075905693
GO:BP GO:0016192 vesicle-mediated transport 0.0117361793104147 2180 136 33 0.242647058823529 0.0151376146788991
GO:BP GO:0120035 regulation of plasma membrane bounded cell projection organization 0.0117361793104147 638 131 15 0.114503816793893 0.0235109717868339
GO:BP GO:0023051 regulation of signaling 0.0117361793104147 3578 131 45 0.343511450381679 0.0125768585802124
GO:BP GO:0001946 lymphangiogenesis 0.0117361793104147 17 79 3 0.0379746835443038 0.176470588235294
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.0122330096518591 1227 131 22 0.16793893129771 0.0179299103504482
GO:BP GO:0031344 regulation of cell projection organization 0.0135497403599152 656 131 15 0.114503816793893 0.0228658536585366
GO:BP GO:0003008 system process 0.0135497403599152 2293 105 28 0.266666666666667 0.0122110771914522
GO:BP GO:0006887 exocytosis 0.0151133021291829 904 132 18 0.136363636363636 0.0199115044247788
GO:BP GO:0010646 regulation of cell communication 0.0151133021291829 3543 131 44 0.33587786259542 0.0124188540784646
GO:BP GO:0036303 lymph vessel morphogenesis 0.0156416912334365 22 79 3 0.0379746835443038 0.136363636363636
GO:BP GO:0032940 secretion by cell 0.0158418758306662 1364 132 23 0.174242424242424 0.0168621700879765
GO:BP GO:0008015 blood circulation 0.0158418758306662 553 50 8 0.16 0.0144665461121157
GO:BP GO:0090208 positive regulation of triglyceride metabolic process 0.0160215388269441 24 76 3 0.0394736842105263 0.125
GO:BP GO:0051641 cellular localization 0.0160215388269441 3541 42 19 0.452380952380952 0.00536571589946343
GO:BP GO:0060415 muscle tissue morphogenesis 0.0166793451121396 69 132 5 0.0378787878787879 0.072463768115942
GO:BP GO:0030335 positive regulation of cell migration 0.0172934149577707 567 79 10 0.126582278481013 0.017636684303351
GO:BP GO:0045055 regulated exocytosis 0.019957207621549 785 49 9 0.183673469387755 0.0114649681528662
GO:BP GO:2000147 positive regulation of cell motility 0.019957207621549 591 79 10 0.126582278481013 0.0169204737732657
GO:BP GO:0140352 export from cell 0.019957207621549 1418 132 23 0.174242424242424 0.0162200282087447
GO:BP GO:0048644 muscle organ morphogenesis 0.019957207621549 76 132 5 0.0378787878787879 0.0657894736842105
GO:BP GO:0051489 regulation of filopodium assembly 0.020260663814182 47 119 4 0.0336134453781513 0.0851063829787234
GO:BP GO:0040017 positive regulation of locomotion 0.0210658957581886 606 79 10 0.126582278481013 0.0165016501650165
GO:BP GO:0051272 positive regulation of cellular component movement 0.0210658957581886 604 79 10 0.126582278481013 0.0165562913907285
GO:BP GO:0001667 ameboidal-type cell migration 0.0210658957581886 494 79 9 0.113924050632911 0.0182186234817814
GO:BP GO:0002576 platelet degranulation 0.0215451417637182 126 132 6 0.0454545454545455 0.0476190476190476
GO:BP GO:0003013 circulatory system process 0.0215451417637182 637 38 7 0.184210526315789 0.010989010989011
GO:BP GO:0071216 cellular response to biotic stimulus 0.0215451417637233 238 131 8 0.0610687022900763 0.0336134453781513
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0215451417637233 2541 22 10 0.454545454545455 0.00393545848091303
GO:BP GO:0048871 multicellular organismal homeostasis 0.0223528717574026 530 129 12 0.0930232558139535 0.0226415094339623
GO:BP GO:2000463 positive regulation of excitatory postsynaptic potential 0.0224866770864038 28 95 3 0.0315789473684211 0.107142857142857
GO:BP GO:0051648 vesicle localization 0.0232393707517366 230 108 7 0.0648148148148148 0.0304347826086957
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.0236834070023419 460 116 10 0.0862068965517241 0.0217391304347826
GO:BP GO:0016477 cell migration 0.0236834070023419 1649 87 18 0.206896551724138 0.0109157064887811
GO:BP GO:0032970 regulation of actin filament-based process 0.0236834070023419 406 49 6 0.122448979591837 0.0147783251231527
GO:BP GO:0034330 cell junction organization 0.0236834070023419 722 49 8 0.163265306122449 0.0110803324099723
GO:BP GO:0035904 aorta development 0.0236834070023419 58 50 3 0.06 0.0517241379310345
GO:BP GO:0031345 negative regulation of cell projection organization 0.0236834070023419 189 63 5 0.0793650793650794 0.0264550264550265
GO:BP GO:0009611 response to wounding 0.0236834070023419 674 5 3 0.6 0.00445103857566766
GO:BP GO:0030104 water homeostasis 0.0236834070023419 83 89 4 0.0449438202247191 0.0481927710843374
GO:BP GO:0010634 positive regulation of epithelial cell migration 0.0236834070023419 181 104 6 0.0576923076923077 0.0331491712707182
GO:BP GO:0046847 filopodium assembly 0.0236834070023419 64 49 3 0.0612244897959184 0.046875
GO:BP GO:0001952 regulation of cell-matrix adhesion 0.0236834070023419 127 95 5 0.0526315789473684 0.0393700787401575
GO:BP GO:0090207 regulation of triglyceride metabolic process 0.0236834070023419 41 76 3 0.0394736842105263 0.0731707317073171
GO:BP GO:0046903 secretion 0.0236834070023419 1501 132 23 0.174242424242424 0.0153231179213857
GO:BP GO:0050891 multicellular organismal water homeostasis 0.0236834070023419 75 89 4 0.0449438202247191 0.0533333333333333
GO:BP GO:0051049 regulation of transport 0.0236834070023419 1809 132 26 0.196969696969697 0.0143725815367606
GO:BP GO:0051246 regulation of protein metabolic process 0.0236834070023419 2704 22 10 0.454545454545455 0.00369822485207101
GO:BP GO:0003205 cardiac chamber development 0.0236834070023419 161 79 5 0.0632911392405063 0.031055900621118
GO:BP GO:0065009 regulation of molecular function 0.0236834070023419 3221 132 39 0.295454545454545 0.0121080409810618
GO:BP GO:0070528 protein kinase C signaling 0.0236834070023419 32 95 3 0.0315789473684211 0.09375
GO:BP GO:0030029 actin filament-based process 0.0254925282514967 808 36 7 0.194444444444444 0.00866336633663366
GO:BP GO:0055008 cardiac muscle tissue morphogenesis 0.0254925282514967 59 132 4 0.0303030303030303 0.0677966101694915
GO:BP GO:0050878 regulation of body fluid levels 0.0254925282514967 514 89 9 0.101123595505618 0.0175097276264591
GO:BP GO:0045834 positive regulation of lipid metabolic process 0.0254925282514967 155 131 6 0.0458015267175573 0.0387096774193548
GO:BP GO:0051491 positive regulation of filopodium assembly 0.0260266853762042 30 119 3 0.0252100840336134 0.1
GO:BP GO:0055010 ventricular cardiac muscle tissue morphogenesis 0.0260266853762042 45 79 3 0.0379746835443038 0.0666666666666667
GO:BP GO:0003091 renal water homeostasis 0.0260266853762042 40 89 3 0.0337078651685393 0.075
GO:BP GO:0060840 artery development 0.0262067870412838 102 79 4 0.0506329113924051 0.0392156862745098
GO:BP GO:0048583 regulation of response to stimulus 0.0262067870412838 4278 131 47 0.358778625954198 0.0109864422627396
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0262067870412838 470 18 4 0.222222222222222 0.00851063829787234
GO:BP GO:0048468 cell development 0.0267434212287311 2100 95 22 0.231578947368421 0.0104761904761905
GO:BP GO:0006814 sodium ion transport 0.0271468786222862 241 120 7 0.0583333333333333 0.029045643153527
GO:BP GO:0050709 negative regulation of protein secretion 0.0271468786222862 78 106 4 0.0377358490566038 0.0512820512820513
GO:BP GO:0051224 negative regulation of protein transport 0.0272519879238747 135 106 5 0.0471698113207547 0.037037037037037
GO:BP GO:0010595 positive regulation of endothelial cell migration 0.0273541347084371 138 104 5 0.0480769230769231 0.036231884057971
GO:BP GO:0055085 transmembrane transport 0.0277007067201174 1635 131 23 0.175572519083969 0.0140672782874618
GO:BP GO:0033674 positive regulation of kinase activity 0.0277007067201174 608 95 10 0.105263157894737 0.0164473684210526
GO:BP GO:1905954 positive regulation of lipid localization 0.0277007067201174 113 77 4 0.051948051948052 0.0353982300884956
GO:BP GO:0048167 regulation of synaptic plasticity 0.0277007067201174 185 117 6 0.0512820512820513 0.0324324324324324
GO:BP GO:0003018 vascular process in circulatory system 0.0277007067201174 256 117 7 0.0598290598290598 0.02734375
GO:BP GO:0003229 ventricular cardiac muscle tissue development 0.0277007067201174 51 79 3 0.0379746835443038 0.0588235294117647
GO:BP GO:0045923 positive regulation of fatty acid metabolic process 0.0277007067201174 38 101 3 0.0297029702970297 0.0789473684210526
GO:BP GO:0046460 neutral lipid biosynthetic process 0.0277007067201174 51 76 3 0.0394736842105263 0.0588235294117647
GO:BP GO:0051650 establishment of vesicle localization 0.0277007067201174 214 102 6 0.0588235294117647 0.0280373831775701
GO:BP GO:0040011 locomotion 0.0277007067201174 2028 87 20 0.229885057471264 0.00986193293885602
GO:BP GO:1904950 negative regulation of establishment of protein localization 0.0277007067201174 139 106 5 0.0471698113207547 0.0359712230215827
GO:BP GO:0010977 negative regulation of neuron projection development 0.0277007067201174 140 63 4 0.0634920634920635 0.0285714285714286
GO:BP GO:0002237 response to molecule of bacterial origin 0.0277007067201174 361 131 9 0.0687022900763359 0.0249307479224377
GO:BP GO:0046463 acylglycerol biosynthetic process 0.0277007067201174 51 76 3 0.0394736842105263 0.0588235294117647
GO:BP GO:0009966 regulation of signal transduction 0.0281577909657956 3165 131 37 0.282442748091603 0.0116903633491311
GO:BP GO:0034694 response to prostaglandin 0.0282779985648828 32 129 3 0.0232558139534884 0.09375
GO:BP GO:0010769 regulation of cell morphogenesis involved in differentiation 0.028362350036483 97 93 4 0.043010752688172 0.0412371134020619
GO:BP GO:0002792 negative regulation of peptide secretion 0.028362350036483 85 106 4 0.0377358490566038 0.0470588235294118
GO:BP GO:0051239 regulation of multicellular organismal process 0.0284738866771683 2861 125 33 0.264 0.011534428521496
GO:BP GO:1905952 regulation of lipid localization 0.0286560998827817 201 77 5 0.0649350649350649 0.0248756218905473
GO:BP GO:0051128 regulation of cellular component organization 0.0286714467509472 2412 119 28 0.235294117647059 0.0116086235489221
GO:BP GO:0010883 regulation of lipid storage 0.0287245111485951 56 76 3 0.0394736842105263 0.0535714285714286
GO:BP GO:0003206 cardiac chamber morphogenesis 0.0292786486756598 120 36 3 0.0833333333333333 0.025
GO:BP GO:0007155 cell adhesion 0.0294275924143888 1492 95 17 0.178947368421053 0.0113941018766756
GO:BP GO:0034765 regulation of ion transmembrane transport 0.0294275924143888 583 17 4 0.235294117647059 0.00686106346483705
GO:BP GO:0098815 modulation of excitatory postsynaptic potential 0.0294275924143888 46 95 3 0.0315789473684211 0.0652173913043478
GO:BP GO:1905897 regulation of response to endoplasmic reticulum stress 0.0294275924143888 84 112 4 0.0357142857142857 0.0476190476190476
GO:BP GO:0003231 cardiac ventricle development 0.0297546971646173 120 79 4 0.0506329113924051 0.0333333333333333
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0297546971646173 253 18 3 0.166666666666667 0.0118577075098814
GO:BP GO:0034762 regulation of transmembrane transport 0.0297546971646173 588 17 4 0.235294117647059 0.00680272108843537
GO:BP GO:0022610 biological adhesion 0.0298376681264315 1499 95 17 0.178947368421053 0.0113408939292862
GO:BP GO:0010648 negative regulation of cell communication 0.0298376681264315 1468 131 21 0.16030534351145 0.0143051771117166
GO:BP GO:0032412 regulation of ion transmembrane transporter activity 0.0298376681264315 270 17 3 0.176470588235294 0.0111111111111111
GO:BP GO:0044092 negative regulation of molecular function 0.0298376681264315 1219 43 9 0.209302325581395 0.007383100902379
GO:BP GO:0045860 positive regulation of protein kinase activity 0.0299068505421484 534 95 9 0.0947368421052632 0.0168539325842697
GO:BP GO:0006903 vesicle targeting 0.0299264221757553 94 102 4 0.0392156862745098 0.0425531914893617
GO:BP GO:0023057 negative regulation of signaling 0.0301908795585903 1471 131 21 0.16030534351145 0.0142760027192386
GO:BP GO:0009306 protein secretion 0.0306166278697589 384 132 9 0.0681818181818182 0.0234375
GO:BP GO:0018108 peptidyl-tyrosine phosphorylation 0.030631648297465 385 132 9 0.0681818181818182 0.0233766233766234
GO:BP GO:0035592 establishment of protein localization to extracellular region 0.030631648297465 385 132 9 0.0681818181818182 0.0233766233766234
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.0309170989521691 1477 131 21 0.16030534351145 0.014218009478673
GO:BP GO:0022898 regulation of transmembrane transporter activity 0.0313126535163448 281 17 3 0.176470588235294 0.0106761565836299
GO:BP GO:0043067 regulation of programmed cell death 0.0313126535163448 1582 131 22 0.16793893129771 0.0139064475347661
GO:BP GO:0018212 peptidyl-tyrosine modification 0.0313853768161911 388 132 9 0.0681818181818182 0.0231958762886598
GO:BP GO:0010466 negative regulation of peptidase activity 0.0315634211434103 267 18 3 0.166666666666667 0.0112359550561798
GO:BP GO:0071692 protein localization to extracellular region 0.0323890497207011 392 132 9 0.0681818181818182 0.0229591836734694
GO:BP GO:0000902 cell morphogenesis 0.0325592682584473 1037 104 14 0.134615384615385 0.0135004821600771
GO:BP GO:0071496 cellular response to external stimulus 0.0325592682584473 322 131 8 0.0610687022900763 0.0248447204968944
GO:BP GO:0051674 localization of cell 0.0325592682584473 1828 87 18 0.206896551724138 0.00984682713347921
GO:BP GO:0048870 cell motility 0.0325592682584473 1828 87 18 0.206896551724138 0.00984682713347921
GO:BP GO:0006928 movement of cell or subcellular component 0.0327135704860564 2311 81 20 0.246913580246914 0.00865426222414539
GO:BP GO:0032409 regulation of transporter activity 0.0329060293806882 297 17 3 0.176470588235294 0.0101010101010101
GO:BP GO:0032496 response to lipopolysaccharide 0.033287342249669 338 99 7 0.0707070707070707 0.0207100591715976
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.0338184619340346 366 29 4 0.137931034482759 0.0109289617486339
GO:BP GO:0010565 regulation of cellular ketone metabolic process 0.0339554529135703 194 129 6 0.0465116279069767 0.0309278350515464
GO:BP GO:0048522 positive regulation of cellular process 0.0339554529135703 5757 133 58 0.43609022556391 0.0100746916796943
GO:BP GO:0051649 establishment of localization in cell 0.0339574433453721 2813 136 34 0.25 0.0120867401350871
GO:BP GO:0009725 response to hormone 0.0339574433453721 921 131 15 0.114503816793893 0.0162866449511401
GO:BP GO:0001954 positive regulation of cell-matrix adhesion 0.0346924966419022 55 95 3 0.0315789473684211 0.0545454545454545
GO:BP GO:0030334 regulation of cell migration 0.0346924966419022 999 87 12 0.137931034482759 0.012012012012012
GO:BP GO:0032989 cellular component morphogenesis 0.0346924966419022 791 96 11 0.114583333333333 0.0139064475347661
GO:BP GO:0051270 regulation of cellular component movement 0.0346924966419022 1141 87 13 0.149425287356322 0.0113935144609991
GO:BP GO:0043473 pigmentation 0.0346924966419022 95 112 4 0.0357142857142857 0.0421052631578947
GO:BP GO:0001934 positive regulation of protein phosphorylation 0.0346924966419022 840 22 5 0.227272727272727 0.00595238095238095
GO:BP GO:0097120 receptor localization to synapse 0.0346924966419022 55 95 3 0.0315789473684211 0.0545454545454545
GO:BP GO:0010737 protein kinase A signaling 0.0346924966419022 40 132 3 0.0227272727272727 0.075
GO:BP GO:0050730 regulation of peptidyl-tyrosine phosphorylation 0.0346924966419022 269 95 6 0.0631578947368421 0.0223048327137546
GO:BP GO:0003279 cardiac septum development 0.0346924966419022 104 50 3 0.06 0.0288461538461538
GO:BP GO:1903531 negative regulation of secretion by cell 0.0346924966419022 152 115 5 0.0434782608695652 0.0328947368421053
GO:BP GO:0061337 cardiac conduction 0.0358396403658507 150 36 3 0.0833333333333333 0.02
GO:BP GO:0051347 positive regulation of transferase activity 0.0358396403658507 689 95 10 0.105263157894737 0.0145137880986938
GO:BP GO:0048878 chemical homeostasis 0.0358396403658507 1229 131 18 0.137404580152672 0.0146460537021969
GO:BP GO:0070372 regulation of ERK1 and ERK2 cascade 0.0358396403658507 309 18 3 0.166666666666667 0.00970873786407767
GO:BP GO:1901654 response to ketone 0.0364428548418537 204 129 6 0.0465116279069767 0.0294117647058824
GO:BP GO:0003208 cardiac ventricle morphogenesis 0.0364428548418537 69 79 3 0.0379746835443038 0.0434782608695652
GO:BP GO:0019216 regulation of lipid metabolic process 0.0364428548418537 419 131 9 0.0687022900763359 0.0214797136038186
GO:BP GO:0051129 negative regulation of cellular component organization 0.0377418565196682 759 117 12 0.102564102564103 0.0158102766798419
GO:BP GO:0042981 regulation of apoptotic process 0.0377418565196682 1549 131 21 0.16030534351145 0.013557133634603
GO:BP GO:0006811 ion transport 0.037769772753861 3661 136 41 0.301470588235294 0.0111991259218793
GO:BP GO:0002790 peptide secretion 0.037769772753861 421 132 9 0.0681818181818182 0.0213776722090261
GO:BP GO:0010721 negative regulation of cell development 0.0379763344687296 183 63 4 0.0634920634920635 0.0218579234972678
GO:BP GO:1903530 regulation of secretion by cell 0.0380208384065651 588 132 11 0.0833333333333333 0.0187074829931973
GO:BP GO:0042592 homeostatic process 0.0380357358998119 1981 131 25 0.190839694656489 0.0126198889449773
GO:BP GO:0070371 ERK1 and ERK2 cascade 0.0384024086598111 329 18 3 0.166666666666667 0.00911854103343465
GO:BP GO:0031401 positive regulation of protein modification process 0.0384024086598111 1074 95 13 0.136842105263158 0.0121042830540037
GO:BP GO:0034142 toll-like receptor 4 signaling pathway 0.0384024086598111 44 131 3 0.0229007633587786 0.0681818181818182
GO:BP GO:0048518 positive regulation of biological process 0.0385107242920024 6363 133 62 0.466165413533835 0.00974383152600974
GO:BP GO:0033036 macromolecule localization 0.0385243481158547 3218 136 37 0.272058823529412 0.0114978247358608
GO:BP GO:0051336 regulation of hydrolase activity 0.0385243481158547 1321 22 6 0.272727272727273 0.00454201362604088
GO:BP GO:0010811 positive regulation of cell-substrate adhesion 0.0389091744867758 124 95 4 0.0421052631578947 0.032258064516129
GO:BP GO:0051247 positive regulation of protein metabolic process 0.0389091744867758 1564 131 21 0.16030534351145 0.0134271099744246
GO:BP GO:0071310 cellular response to organic substance 0.0389192647752004 2776 131 32 0.244274809160305 0.0115273775216138
GO:BP GO:0071345 cellular response to cytokine stimulus 0.0389192647752004 1132 6 3 0.5 0.00265017667844523
GO:BP GO:0071322 cellular response to carbohydrate stimulus 0.0389192647752004 148 129 5 0.0387596899224806 0.0337837837837838
GO:BP GO:1904062 regulation of cation transmembrane transport 0.0392510460954021 360 17 3 0.176470588235294 0.00833333333333333
GO:BP GO:2000177 regulation of neural precursor cell proliferation 0.0392510460954021 91 131 4 0.0305343511450382 0.043956043956044
GO:BP GO:0042327 positive regulation of phosphorylation 0.0399376403765052 927 22 5 0.227272727272727 0.00539374325782093
GO:BP GO:0046890 regulation of lipid biosynthetic process 0.0399403062701022 215 129 6 0.0465116279069767 0.027906976744186
GO:BP GO:0046620 regulation of organ growth 0.0406327391461121 111 109 4 0.036697247706422 0.036036036036036
GO:BP GO:0071219 cellular response to molecule of bacterial origin 0.0408573942607067 214 131 6 0.0458015267175573 0.0280373831775701
GO:BP GO:0031346 positive regulation of cell projection organization 0.0408573942607067 359 131 8 0.0610687022900763 0.0222841225626741
GO:BP GO:0050886 endocrine process 0.0408573942607067 82 74 3 0.0405405405405405 0.0365853658536585
GO:BP GO:2000145 regulation of cell motility 0.0408573942607067 1061 87 12 0.137931034482759 0.0113100848256362
GO:BP GO:0050790 regulation of catalytic activity 0.0408573942607067 2545 132 30 0.227272727272727 0.0117878192534381
GO:BP GO:0044087 regulation of cellular component biogenesis 0.0408573942607067 990 129 15 0.116279069767442 0.0151515151515152
GO:BP GO:0010647 positive regulation of cell communication 0.0408573942607067 1777 117 21 0.179487179487179 0.0118176702307259
GO:BP GO:0023056 positive regulation of signaling 0.0413839012875882 1782 117 21 0.179487179487179 0.0117845117845118
GO:BP GO:0000904 cell morphogenesis involved in differentiation 0.0418069016267699 749 93 10 0.10752688172043 0.0133511348464619
GO:BP GO:0045861 negative regulation of proteolysis 0.0418069016267699 359 35 4 0.114285714285714 0.011142061281337
GO:BP GO:0009967 positive regulation of signal transduction 0.0418069016267699 1598 114 19 0.166666666666667 0.0118898623279099
GO:BP GO:0030036 actin cytoskeleton organization 0.0418069016267699 709 29 5 0.172413793103448 0.00705218617771509
GO:BP GO:0061024 membrane organization 0.0418069016267699 973 40 7 0.175 0.00719424460431655
GO:BP GO:0043408 regulation of MAPK cascade 0.0420891304051386 730 18 4 0.222222222222222 0.00547945205479452
GO:BP GO:0014032 neural crest cell development 0.0420907835664479 80 79 3 0.0379746835443038 0.0375
GO:BP GO:0090066 regulation of anatomical structure size 0.0420907835664479 518 93 8 0.0860215053763441 0.0154440154440154
GO:BP GO:0034446 substrate adhesion-dependent cell spreading 0.0420907835664479 109 58 3 0.0517241379310345 0.0275229357798165
GO:BP GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 0.042821972069809 106 119 4 0.0336134453781513 0.0377358490566038
GO:BP GO:0043269 regulation of ion transport 0.0428223316401166 1379 132 19 0.143939393939394 0.0137781000725163
GO:BP GO:0034097 response to cytokine 0.0428529303306322 1226 6 3 0.5 0.00244698205546493
GO:BP GO:0051048 negative regulation of secretion 0.0428930551823386 176 115 5 0.0434782608695652 0.0284090909090909
GO:BP GO:0035725 sodium ion transmembrane transport 0.0434727593961122 171 38 3 0.0789473684210526 0.0175438596491228
GO:BP GO:0010033 response to organic substance 0.0434767324307272 3412 131 37 0.282442748091603 0.0108440797186401
GO:BP GO:0010975 regulation of neuron projection development 0.0434767324307272 451 131 9 0.0687022900763359 0.0199556541019956
GO:BP GO:0010817 regulation of hormone levels 0.0437294145977242 536 131 10 0.0763358778625954 0.0186567164179104
GO:BP GO:0019915 lipid storage 0.0439660984795421 86 76 3 0.0394736842105263 0.0348837209302326
GO:BP GO:0030162 regulation of proteolysis 0.0440696081530662 752 40 6 0.15 0.00797872340425532
GO:BP GO:0010941 regulation of cell death 0.0442806747903868 1720 131 22 0.16793893129771 0.0127906976744186
GO:BP GO:0050708 regulation of protein secretion 0.0442806747903868 295 132 7 0.053030303030303 0.023728813559322
GO:BP GO:0006690 icosanoid metabolic process 0.0442806747903868 124 105 4 0.0380952380952381 0.032258064516129
GO:BP GO:0014031 mesenchymal cell development 0.0442806747903868 84 79 3 0.0379746835443038 0.0357142857142857
GO:BP GO:0048864 stem cell development 0.0442806747903868 84 79 3 0.0379746835443038 0.0357142857142857
GO:BP GO:0048208 COPII vesicle coating 0.0442806747903868 65 102 3 0.0294117647058824 0.0461538461538462
GO:BP GO:0048207 vesicle targeting, rough ER to cis-Golgi 0.0442806747903868 65 102 3 0.0294117647058824 0.0461538461538462
GO:BP GO:0010001 glial cell differentiation 0.0442896397215234 225 131 6 0.0458015267175573 0.0266666666666667
GO:BP GO:0032370 positive regulation of lipid transport 0.0448940807776258 87 77 3 0.038961038961039 0.0344827586206897
GO:BP GO:0045937 positive regulation of phosphate metabolic process 0.0449452826340429 1001 22 5 0.227272727272727 0.004995004995005
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 0.0449452826340429 1001 22 5 0.227272727272727 0.004995004995005
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 0.0449452826340429 2255 7 4 0.571428571428571 0.00177383592017738
GO:BP GO:0003014 renal system process 0.045076909877718 126 105 4 0.0380952380952381 0.0317460317460317
GO:BP GO:0019752 carboxylic acid metabolic process 0.0450852040611181 1024 105 13 0.123809523809524 0.0126953125
GO:BP GO:0010810 regulation of cell-substrate adhesion 0.0451128785382462 222 95 5 0.0526315789473684 0.0225225225225225
GO:BP GO:1901699 cellular response to nitrogen compound 0.0451128785382462 724 131 12 0.0916030534351145 0.0165745856353591
GO:BP GO:0002224 toll-like receptor signaling pathway 0.0451410269470577 161 131 5 0.0381679389312977 0.031055900621118
GO:BP GO:0033993 response to lipid 0.0451410269470577 918 117 13 0.111111111111111 0.014161220043573
GO:BP GO:0040012 regulation of locomotion 0.0452594990990324 1104 87 12 0.137931034482759 0.0108695652173913
GO:BP GO:0034329 cell junction assembly 0.0454040390107328 438 49 5 0.102040816326531 0.0114155251141553
GO:BP GO:0071384 cellular response to corticosteroid stimulus 0.0455815826732318 63 109 3 0.0275229357798165 0.0476190476190476
GO:BP GO:0014706 striated muscle tissue development 0.0460688399209286 380 36 4 0.111111111111111 0.0105263157894737
GO:BP GO:0023052 signaling 0.0462774346759199 6810 132 64 0.484848484848485 0.00939794419970631
GO:BP GO:0019217 regulation of fatty acid metabolic process 0.0466217243911735 105 129 4 0.0310077519379845 0.0380952380952381
GO:BP GO:0050804 modulation of chemical synaptic transmission 0.0466741133707228 430 117 8 0.0683760683760684 0.0186046511627907
GO:BP GO:0046888 negative regulation of hormone secretion 0.0467338667173599 66 106 3 0.0283018867924528 0.0454545454545455
GO:BP GO:0099177 regulation of trans-synaptic signaling 0.0467584998482517 431 117 8 0.0683760683760684 0.0185614849187935
GO:BP GO:0006901 vesicle coating 0.0468049631418765 69 102 3 0.0294117647058824 0.0434782608695652
GO:BP GO:0060193 positive regulation of lipase activity 0.0476127823603821 75 95 3 0.0315789473684211 0.04
GO:BP GO:0007154 cell communication 0.0476127823603821 6829 132 64 0.484848484848485 0.009371796749158
GO:BP GO:0031331 positive regulation of cellular catabolic process 0.0476127823603821 393 129 8 0.062015503875969 0.0203562340966921
GO:BP GO:0032870 cellular response to hormone stimulus 0.0476127823603821 645 131 11 0.083969465648855 0.0170542635658915
GO:BP GO:0048771 tissue remodeling 0.0476127823603821 186 117 5 0.0427350427350427 0.0268817204301075
GO:BP GO:0014033 neural crest cell differentiation 0.0476127823603821 90 79 3 0.0379746835443038 0.0333333333333333
GO:BP GO:0044264 cellular polysaccharide metabolic process 0.0479972217643636 107 67 3 0.0447761194029851 0.0280373831775701
GO:BP GO:0006935 chemotaxis 0.0479972217643636 653 22 4 0.181818181818182 0.00612557427258806
GO:BP GO:0009617 response to bacterium 0.0481189418969208 743 99 10 0.101010101010101 0.0134589502018843
GO:BP GO:0008104 protein localization 0.0481189418969208 2770 136 32 0.235294117647059 0.0115523465703971
GO:BP GO:0043410 positive regulation of MAPK cascade 0.0481189418969208 539 95 8 0.0842105263157895 0.0148423005565863
GO:BP GO:0042330 taxis 0.0481884774248915 656 22 4 0.181818181818182 0.00609756097560976
GO:BP GO:0035637 multicellular organismal signaling 0.0490820610617324 204 36 3 0.0833333333333333 0.0147058823529412
GO:BP GO:0034220 ion transmembrane transport 0.0490820610617324 1397 17 5 0.294117647058824 0.00357909806728704
GO:BP GO:0090114 COPII-coated vesicle budding 0.0492570504007776 72 102 3 0.0294117647058824 0.0416666666666667
GO:BP GO:0007605 sensory perception of sound 0.0492570504007776 153 48 3 0.0625 0.0196078431372549
GO:BP GO:0051046 regulation of secretion 0.0492570504007776 647 132 11 0.0833333333333333 0.0170015455950541
GO:BP GO:0042304 regulation of fatty acid biosynthetic process 0.0492570504007776 57 129 3 0.0232558139534884 0.0526315789473684
GO:BP GO:0035773 insulin secretion involved in cellular response to glucose stimulus 0.0492570504007776 69 106 3 0.0283018867924528 0.0434782608695652
GO:BP GO:0009893 positive regulation of metabolic process 0.0492570504007776 3783 133 40 0.300751879699248 0.0105736188210415
GO:BP GO:0060537 muscle tissue development 0.0492570504007776 399 36 4 0.111111111111111 0.0100250626566416
GO:BP GO:0043436 oxoacid metabolic process 0.0497561101550621 1057 105 13 0.123809523809524 0.0122989593188269
GO:BP GO:0048199 vesicle targeting, to, from or within Golgi 0.0497600812004606 73 102 3 0.0294117647058824 0.0410958904109589
GO:BP GO:0019933 cAMP-mediated signaling 0.0497600812004606 69 108 3 0.0277777777777778 0.0434782608695652
GO:BP GO:0010770 positive regulation of cell morphogenesis involved in differentiation 0.0497600812004606 80 93 3 0.032258064516129 0.0375
GO:CC GO:0071944 cell periphery 1.76390196844133e-05 6169 120 68 0.566666666666667 0.0110228562165667
GO:CC GO:0005886 plasma membrane 0.000106811160002004 5681 120 62 0.516666666666667 0.0109135715543038
GO:CC GO:0005938 cell cortex 0.000422481178203813 311 115 11 0.0956521739130435 0.0353697749196141
GO:CC GO:0016020 membrane 0.00110795218474062 9838 126 89 0.706349206349206 0.00904655417767839
GO:CC GO:0030054 cell junction 0.00110795218474062 2105 131 32 0.244274809160305 0.0152019002375297
GO:CC GO:0097708 intracellular vesicle 0.00165435844486837 2428 135 35 0.259259259259259 0.0144151565074135
GO:CC GO:0031410 cytoplasmic vesicle 0.00165435844486837 2424 135 35 0.259259259259259 0.0144389438943894
GO:CC GO:0098685 Schaffer collateral - CA1 synapse 0.00235654136242942 80 95 5 0.0526315789473684 0.0625
GO:CC GO:0031982 vesicle 0.00235654136242942 4055 135 49 0.362962962962963 0.0120838471023428
GO:CC GO:0098793 presynapse 0.00250357831438666 521 50 8 0.16 0.0153550863723608
GO:CC GO:0099503 secretory vesicle 0.00278548034940077 1020 43 10 0.232558139534884 0.00980392156862745
GO:CC GO:0098590 plasma membrane region 0.00282770665738652 1240 119 20 0.168067226890756 0.0161290322580645
GO:CC GO:0031226 intrinsic component of plasma membrane 0.00282770665738652 1726 94 21 0.223404255319149 0.0121668597914253
GO:CC GO:0031225 anchored component of membrane 0.00321740070780994 174 82 6 0.0731707317073171 0.0344827586206897
GO:CC GO:0045202 synapse 0.00379382089363052 1349 131 22 0.16793893129771 0.0163083765752409
GO:CC GO:0098588 bounding membrane of organelle 0.00569277054709169 2158 135 30 0.222222222222222 0.0139017608897127
GO:CC GO:0098984 neuron to neuron synapse 0.00569277054709169 366 131 10 0.0763358778625954 0.0273224043715847
GO:CC GO:0031983 vesicle lumen 0.00647318842005377 326 35 5 0.142857142857143 0.0153374233128834
GO:CC GO:0034774 secretory granule lumen 0.00647318842005377 320 35 5 0.142857142857143 0.015625
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.00647318842005377 324 35 5 0.142857142857143 0.0154320987654321
GO:CC GO:0030141 secretory granule 0.00959788280319029 851 42 8 0.19047619047619 0.00940070505287897
GO:CC GO:0014069 postsynaptic density 0.00959788280319029 334 131 9 0.0687022900763359 0.0269461077844311
GO:CC GO:0005788 endoplasmic reticulum lumen 0.00985588551196104 307 43 5 0.116279069767442 0.0162866449511401
GO:CC GO:0031224 intrinsic component of membrane 0.00985588551196104 5868 119 54 0.453781512605042 0.00920245398773006
GO:CC GO:0005811 lipid droplet 0.00985588551196104 95 33 3 0.0909090909090909 0.0315789473684211
GO:CC GO:0032279 asymmetric synapse 0.00985588551196104 340 131 9 0.0687022900763359 0.0264705882352941
GO:CC GO:0044853 plasma membrane raft 0.0104648242778199 116 29 3 0.103448275862069 0.0258620689655172
GO:CC GO:0098978 glutamatergic synapse 0.0104648242778199 349 131 9 0.0687022900763359 0.0257879656160458
GO:CC GO:0005576 extracellular region 0.0112796660925201 4567 5 5 1 0.00109481059776659
GO:CC GO:0099572 postsynaptic specialization 0.011664440321886 358 131 9 0.0687022900763359 0.0251396648044693
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.0125045902220154 779 75 10 0.133333333333333 0.0128369704749679
GO:CC GO:0043005 neuron projection 0.0130743652353942 1380 129 20 0.155038759689922 0.0144927536231884
GO:CC GO:0005887 integral component of plasma membrane 0.0133041958856221 1645 94 18 0.191489361702128 0.0109422492401216
GO:CC GO:0012506 vesicle membrane 0.0139801623471356 800 75 10 0.133333333333333 0.0125
GO:CC GO:0030133 transport vesicle 0.014071104797198 414 75 7 0.0933333333333333 0.0169082125603865
GO:CC GO:0005615 extracellular space 0.0141026244310481 3594 4 4 1 0.00111296605453534
GO:CC GO:0030018 Z disc 0.0141026244310481 126 72 4 0.0555555555555556 0.0317460317460317
GO:CC GO:0055037 recycling endosome 0.0141026244310481 188 82 5 0.0609756097560976 0.0265957446808511
GO:CC GO:0070161 anchoring junction 0.0141726943942135 836 39 7 0.179487179487179 0.00837320574162679
GO:CC GO:0031090 organelle membrane 0.0151199086989059 3612 117 36 0.307692307692308 0.00996677740863787
GO:CC GO:0098794 postsynapse 0.0151677997838689 639 131 12 0.0916030534351145 0.0187793427230047
GO:CC GO:0099738 cell cortex region 0.0163075044464004 42 108 3 0.0277777777777778 0.0714285714285714
GO:CC GO:0031674 I band 0.0172089186101695 139 72 4 0.0555555555555556 0.0287769784172662
GO:CC GO:0012505 endomembrane system 0.0194976622932588 4640 131 47 0.358778625954198 0.0101293103448276
GO:CC GO:0005911 cell-cell junction 0.0194976622932588 494 131 10 0.0763358778625954 0.0202429149797571
GO:CC GO:0030863 cortical cytoskeleton 0.0244617380280493 107 108 4 0.037037037037037 0.0373831775700935
GO:CC GO:0030312 external encapsulating structure 0.0278834372026439 563 51 6 0.117647058823529 0.0106571936056838
GO:CC GO:0005829 cytosol 0.0318176764352018 5303 132 51 0.386363636363636 0.00961719781255893
GO:CC GO:0099512 supramolecular fiber 0.0318176764352018 993 136 15 0.110294117647059 0.0151057401812689
GO:CC GO:0099081 supramolecular polymer 0.032745226764011 1001 136 15 0.110294117647059 0.014985014985015
GO:CC GO:0030424 axon 0.032745226764011 660 129 11 0.0852713178294574 0.0166666666666667
GO:CC GO:0055038 recycling endosome membrane 0.0330714684785256 84 82 3 0.0365853658536585 0.0357142857142857
GO:CC GO:0009898 cytoplasmic side of plasma membrane 0.0353079314822443 168 131 5 0.0381679389312977 0.0297619047619048
GO:CC GO:0036477 somatodendritic compartment 0.0358284012062859 871 129 13 0.10077519379845 0.0149253731343284
GO:CC GO:0005912 adherens junction 0.0388094106360933 173 131 5 0.0381679389312977 0.0289017341040462
GO:CC GO:0042734 presynaptic membrane 0.0393510640905967 150 50 3 0.06 0.02
GO:CC GO:0005737 cytoplasm 0.0412738074917814 11911 53 42 0.792452830188679 0.00352615229619679
GO:CC GO:0030017 sarcomere 0.0412738074917814 208 72 4 0.0555555555555556 0.0192307692307692
GO:CC GO:0120025 plasma membrane bounded cell projection 0.0412738074917814 2229 129 25 0.193798449612403 0.0112157918349035
GO:CC GO:0034451 centriolar satellite 0.0412915882588623 107 75 3 0.04 0.0280373831775701
GO:CC GO:0048786 presynaptic active zone 0.0418817533213605 75 108 3 0.0277777777777778 0.04
GO:CC GO:0019867 outer membrane 0.0473267770330809 229 109 5 0.0458715596330275 0.0218340611353712
GO:CC GO:0098552 side of membrane 0.0485817129355935 619 131 10 0.0763358778625954 0.0161550888529887
GO:CC GO:0098562 cytoplasmic side of membrane 0.0499705070142271 194 131 5 0.0381679389312977 0.0257731958762887
TF TF:M00196_1 Factor: Sp1; motif: NGGGGGCGGGGYN; match class: 1 0.00449903829493271 5919 130 65 0.5 0.0109815847271499
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 0.00449903829493271 6334 130 68 0.523076923076923 0.0107357120303126
TF TF:M07129_1 Factor: Sp2; motif: GYCCCGCCYCYNNNN; match class: 1 0.0166527286916113 2422 96 28 0.291666666666667 0.0115606936416185
TF TF:M00933 Factor: Sp1; motif: CCCCGCCCCN 0.023325303663362 9715 131 88 0.67175572519084 0.00905815748841997
TF TF:M09658 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS 0.023325303663362 5262 136 58 0.426470588235294 0.0110224249334854
TF TF:M00931_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.023325303663362 5905 130 61 0.469230769230769 0.0103302286198137
TF TF:M07615 Factor: Sp3; motif: GGGGCGGGGSNN 0.023325303663362 6807 130 67 0.515384615384615 0.00984280887321875
TF TF:M09765_1 Factor: SP1; motif: NRGKGGGCGGGGCN; match class: 1 0.023325303663362 3318 129 41 0.317829457364341 0.0123568414707655
TF TF:M10072_1 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR; match class: 1 0.023325303663362 6225 136 65 0.477941176470588 0.0104417670682731
TF TF:M06380 Factor: ZNF787; motif: SGTGGTAMTGATM 0.023325303663362 48 63 4 0.0634920634920635 0.0833333333333333
TF TF:M00008_1 Factor: Sp1; motif: GGGGCGGGGT; match class: 1 0.023325303663362 4937 136 55 0.404411764705882 0.0111403686449261
TF TF:M01973_1 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC; match class: 1 0.023325303663362 2398 101 27 0.267326732673267 0.0112593828190158
TF TF:M09970_1 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN; match class: 1 0.023325303663362 3783 129 44 0.341085271317829 0.0116309807031457
TF TF:M07063 Factor: Sp1; motif: GGGGCGGGGC 0.023325303663362 7696 130 73 0.561538461538462 0.00948544698544699
TF TF:M10435 Factor: Sp2; motif: GGGGCGGGG 0.023325303663362 7696 130 73 0.561538461538462 0.00948544698544699
TF TF:M00933_1 Factor: Sp1; motif: CCCCGCCCCN; match class: 1 0.0240800276257719 5166 131 55 0.419847328244275 0.0106465350367789
TF TF:M00932_1 Factor: Sp1; motif: NNGGGGCGGGGNN; match class: 1 0.0263533646846355 6047 130 61 0.469230769230769 0.0100876467669919
TF TF:M08960 Factor: PPARALPHA:RXR-ALPHA; motif: AWNTRGGTNAAAGGTCAN 0.0284366168687758 11671 43 37 0.86046511627907 0.00317025104961014
TF TF:M09970 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN 0.0284366168687758 7728 130 72 0.553846153846154 0.0093167701863354
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.0284366168687758 9162 134 84 0.626865671641791 0.0091683038637852
TF TF:M09973_1 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN; match class: 1 0.0284366168687758 6607 129 64 0.496124031007752 0.00968669592856062
TF TF:M09723_1 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS; match class: 1 0.0284366168687758 6113 136 63 0.463235294117647 0.0103059054474072
TF TF:M07409 Factor: BTEB2; motif: GCCCCRCCCH 0.0284366168687758 5198 130 54 0.415384615384615 0.0103886110042324
TF TF:M07409_1 Factor: BTEB2; motif: GCCCCRCCCH; match class: 1 0.0284366168687758 1829 114 24 0.210526315789474 0.0131219245489338
TF TF:M03920 Factor: SP1; motif: RCCMCRCCCMC 0.0284366168687758 7283 130 69 0.530769230769231 0.00947411780859536
TF TF:M01042 Factor: GLI1; motif: GACCACCCAV 0.0284366168687758 1885 92 21 0.228260869565217 0.0111405835543767
TF TF:M07129 Factor: Sp2; motif: GYCCCGCCYCYNNNN 0.0284366168687758 6260 130 62 0.476923076923077 0.00990415335463259
TF TF:M01973 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC 0.0284366168687758 6167 134 63 0.470149253731343 0.0102156640181612
TF TF:M00450_1 Factor: Zic3; motif: NGGGKGGTC; match class: 1 0.0284366168687758 7927 126 72 0.571428571428571 0.00908288129178756
TF TF:M09969 Factor: EKLF; motif: NGGGYGKGGCNNGG 0.0284366168687758 4589 136 51 0.375 0.0111135323599913
TF TF:M11935_1 Factor: Oct3; motif: NNWTATGYWAATKANN; match class: 1 0.0298909005517186 530 44 7 0.159090909090909 0.0132075471698113
TF TF:M09765 Factor: SP1; motif: NRGKGGGCGGGGCN 0.0298909005517186 7469 130 70 0.538461538461538 0.00937207122774133
TF TF:M03871 Factor: GLI; motif: MCVNNGACCACCCAV 0.0298909005517186 3331 100 32 0.32 0.00960672470729511
TF TF:M10071_1 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG; match class: 1 0.0298909005517186 4623 129 49 0.37984496124031 0.0105991780229288
TF TF:M09967 Factor: AP-2rep; motif: NGGGGCGGGGC 0.0316574249285085 4023 136 46 0.338235294117647 0.0114342530449913
TF TF:M07063_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.0325114412058186 3495 134 41 0.305970149253731 0.0117310443490701
TF TF:M10435_1 Factor: Sp2; motif: GGGGCGGGG; match class: 1 0.0325114412058186 3495 134 41 0.305970149253731 0.0117310443490701
TF TF:M01837 Factor: FKLF; motif: BGGGNGGVMD 0.0326676051524227 5442 133 56 0.421052631578947 0.0102903344358692
TF TF:M04259 Factor: FOXO3; motif: GTAAACAW 0.0326676051524227 2079 10 6 0.6 0.00288600288600289
TF TF:M01303_1 Factor: SP1; motif: GGGGYGGGGNS; match class: 1 0.0326676051524227 3507 134 41 0.305970149253731 0.0116909039064728
TF TF:M09619 Factor: HNF-3beta; motif: TGTTTACWYWG 0.0326676051524227 3168 10 7 0.7 0.00220959595959596
TF TF:M08867_1 Factor: AP2; motif: GCCYGSGGSN; match class: 1 0.0327198697134529 5186 136 55 0.404411764705882 0.0106054762822985
TF TF:M12351 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC 0.032798665101195 12302 131 101 0.770992366412214 0.0082100471468054
TF TF:M09723 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS 0.0328150942910641 10156 123 83 0.67479674796748 0.0081725088617566
TF TF:M03807_1 Factor: SP2; motif: GNNGGGGGCGGGGSN; match class: 1 0.0331550375967945 4199 136 47 0.345588235294118 0.011193141224101
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.0343608486227361 8180 136 77 0.566176470588235 0.00941320293398533
TF TF:M07615_1 Factor: Sp3; motif: GGGGCGGGGSNN; match class: 1 0.0343608486227361 2885 127 34 0.267716535433071 0.0117850953206239
TF TF:M01273_1 Factor: SP4; motif: SCCCCGCCCCS; match class: 1 0.0354850907040213 1016 93 14 0.150537634408602 0.0137795275590551
TF TF:M12157 Factor: KLF15; motif: RCCACGCCCCCC 0.0354850907040213 3619 136 42 0.308823529411765 0.011605415860735
TF TF:M11909 Factor: POU3F2; motif: NTATGCWAATKAG 0.0354850907040213 5127 20 13 0.65 0.00253559586502828
TF TF:M07226 Factor: SP1; motif: NCCCCKCCCCC 0.0385338090904348 8292 131 75 0.572519083969466 0.00904486251808972
TF TF:M09967_1 Factor: AP-2rep; motif: NGGGGCGGGGC; match class: 1 0.0399678609210213 1379 96 17 0.177083333333333 0.0123277737490935
TF TF:M03582 Factor: TWIST; motif: CACCTGG 0.04236813512567 8446 92 56 0.608695652173913 0.00663035756571158
TF TF:M00448_1 Factor: Zic1; motif: KGGGTGGTC; match class: 1 0.04236813512567 4300 93 35 0.376344086021505 0.00813953488372093
TF TF:M07290 Factor: GLI; motif: NGACCMCCCAN 0.0428864735350075 7127 93 50 0.537634408602151 0.00701557457555774
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.0438727149113458 10357 134 90 0.671641791044776 0.00868977503137974
TF TF:M10529 Factor: Sp1; motif: RGGGMGGRGSNGGGG 0.0453182641312498 6891 129 64 0.496124031007752 0.00928747641851691
TF TF:M00649 Factor: MAZ; motif: GGGGAGGG 0.0457558553218548 9327 78 52 0.666666666666667 0.00557521175083092
TF TF:M07289_1 Factor: GKLF; motif: NNNRGGNGNGGSN; match class: 1 0.0464716248550582 10555 129 88 0.682170542635659 0.00833728090952155
TF TF:M03560_1 Factor: PMX1; motif: TAATHA; match class: 1 0.0464716248550582 10273 16 15 0.9375 0.00146013822641877
TF TF:M08886 Factor: IRF4; motif: MNNRAAANGAAA 0.0464716248550582 4107 7 6 0.857142857142857 0.0014609203798393
TF TF:M09973 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN 0.0464716248550582 10853 134 93 0.694029850746269 0.00856905924629135
TF TF:M07277_1 Factor: BTEB2; motif: RGGGNGKGGN; match class: 1 0.0464716248550582 4149 130 44 0.338461538461538 0.0106049650518197
TF TF:M01104 Factor: MOVO-B; motif: GNGGGGG 0.0489486330369902 10261 134 89 0.664179104477612 0.00867361855569633
TF TF:M00450 Factor: Zic3; motif: NGGGKGGTC 0.0499676071657226 14000 93 80 0.860215053763441 0.00571428571428571

pS23 transcription factor target enrichment of top program genes

TF enrichment of pS23
TFs corrosponding to activation of pS23. (Left) pearson correlation of TF expression and gene expression program activatity in Stromal cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.