pEpi34 program activity among Epithelial cells

Activation of pEpi34
pEpi34 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpi34 by different cell subtypes
pEpi34 gene program activation among cells of different subtypes (Epithelial cells).

pEpi34 top program genes

Top genes of pEpi34 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpi34 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpi34
pEpi34 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0006955 immune response 4.80913409800379e-38 2311 141 86 0.609929078014184 0.0372133275638252
GO:BP GO:0002376 immune system process 1.33777461648889e-31 3278 142 92 0.647887323943662 0.0280658938377059
GO:BP GO:0006952 defense response 2.00901320628553e-26 1818 106 57 0.537735849056604 0.0313531353135314
GO:BP GO:0051707 response to other organism 1.77043618053679e-25 1592 98 51 0.520408163265306 0.032035175879397
GO:BP GO:0043207 response to external biotic stimulus 1.77043618053679e-25 1594 98 51 0.520408163265306 0.0319949811794228
GO:BP GO:0009607 response to biotic stimulus 3.77925791492956e-25 1626 98 51 0.520408163265306 0.0313653136531365
GO:BP GO:0098542 defense response to other organism 2.16198370396016e-24 1218 98 45 0.459183673469388 0.0369458128078818
GO:BP GO:0045087 innate immune response 1.92956921187095e-22 998 98 40 0.408163265306122 0.0400801603206413
GO:BP GO:0002684 positive regulation of immune system process 7.21930478706801e-22 1065 129 46 0.356589147286822 0.0431924882629108
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 1.13752576401765e-20 2255 98 53 0.540816326530612 0.0235033259423503
GO:BP GO:0002682 regulation of immune system process 1.13752576401765e-20 1617 141 56 0.397163120567376 0.0346320346320346
GO:BP GO:0050776 regulation of immune response 2.1401211872093e-20 996 141 45 0.319148936170213 0.0451807228915663
GO:BP GO:0034341 response to interferon-gamma 1.03190918417393e-19 196 141 24 0.170212765957447 0.122448979591837
GO:BP GO:0019882 antigen processing and presentation 3.47254962714683e-18 234 58 18 0.310344827586207 0.0769230769230769
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 3.88828441217333e-18 192 58 17 0.293103448275862 0.0885416666666667
GO:BP GO:0009605 response to external stimulus 6.14448872413846e-18 2944 98 56 0.571428571428571 0.0190217391304348
GO:BP GO:0050778 positive regulation of immune response 1.4265086457792e-17 753 141 37 0.26241134751773 0.049136786188579
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 2.68555313370901e-17 174 58 16 0.275862068965517 0.0919540229885057
GO:BP GO:0002250 adaptive immune response 3.26847903847114e-17 689 139 35 0.251798561151079 0.0507982583454282
GO:BP GO:0034097 response to cytokine 4.5768956303686e-17 1226 141 45 0.319148936170213 0.0367047308319739
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 4.5768956303686e-17 182 58 16 0.275862068965517 0.0879120879120879
GO:BP GO:0001775 cell activation 4.5768956303686e-17 1495 129 47 0.364341085271318 0.031438127090301
GO:BP GO:0019221 cytokine-mediated signaling pathway 6.75897210510373e-17 810 131 36 0.274809160305344 0.0444444444444444
GO:BP GO:0071345 cellular response to cytokine stimulus 9.21090301986442e-17 1132 141 43 0.304964539007092 0.0379858657243816
GO:BP GO:0045321 leukocyte activation 1.28305715540305e-16 1332 129 44 0.341085271317829 0.033033033033033
GO:BP GO:0071346 cellular response to interferon-gamma 7.40967767938299e-16 175 141 20 0.141843971631206 0.114285714285714
GO:BP GO:0046649 lymphocyte activation 1.67685002490291e-15 771 142 35 0.246478873239437 0.0453955901426719
GO:BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 4.34662991633659e-15 103 10 8 0.8 0.0776699029126214
GO:BP GO:0048584 positive regulation of response to stimulus 9.22676658350725e-15 2344 142 58 0.408450704225352 0.0247440273037543
GO:BP GO:0019883 antigen processing and presentation of endogenous antigen 3.57920972901433e-14 26 39 8 0.205128205128205 0.307692307692308
GO:BP GO:0006950 response to stress 2.21816588011898e-13 4170 100 60 0.6 0.0143884892086331
GO:BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 3.45541537303186e-13 96 9 7 0.777777777777778 0.0729166666666667
GO:BP GO:0002396 MHC protein complex assembly 4.12579338844084e-13 7 55 6 0.109090909090909 0.857142857142857
GO:BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 4.36597303597238e-13 100 9 7 0.777777777777778 0.07
GO:BP GO:0042110 T cell activation 5.05052313728632e-13 489 139 26 0.18705035971223 0.0531697341513292
GO:BP GO:0002483 antigen processing and presentation of endogenous peptide antigen 5.49270725875247e-13 19 39 7 0.179487179487179 0.368421052631579
GO:BP GO:0001819 positive regulation of cytokine production 9.76673991448311e-13 452 141 25 0.177304964539007 0.0553097345132743
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 3.01084573262611e-12 88 33 9 0.272727272727273 0.102272727272727
GO:BP GO:0009617 response to bacterium 7.40026890161923e-12 743 97 25 0.257731958762887 0.0336473755047106
GO:BP GO:0050865 regulation of cell activation 8.13859898859424e-12 655 139 28 0.201438848920863 0.0427480916030534
GO:BP GO:0002252 immune effector process 1.27261687049939e-11 1309 129 37 0.286821705426357 0.0282658517952636
GO:BP GO:0002503 peptide antigen assembly with MHC class II protein complex 3.11262510449434e-11 4 16 4 0.25 1
GO:BP GO:0002399 MHC class II protein complex assembly 3.11262510449434e-11 4 16 4 0.25 1
GO:BP GO:0001817 regulation of cytokine production 4.56486273414123e-11 806 141 30 0.212765957446809 0.0372208436724566
GO:BP GO:0070661 leukocyte proliferation 5.01631894853768e-11 325 139 20 0.143884892086331 0.0615384615384615
GO:BP GO:0002253 activation of immune response 6.04761548225356e-11 568 125 24 0.192 0.0422535211267606
GO:BP GO:0002694 regulation of leukocyte activation 6.40464214768318e-11 610 139 26 0.18705035971223 0.0426229508196721
GO:BP GO:0002501 peptide antigen assembly with MHC protein complex 8.8072000385312e-11 6 55 5 0.0909090909090909 0.833333333333333
GO:BP GO:0006954 inflammatory response 1.26067658444983e-10 794 121 27 0.223140495867769 0.0340050377833753
GO:BP GO:0001816 cytokine production 1.29688791170844e-10 844 141 30 0.212765957446809 0.0355450236966825
GO:BP GO:0030593 neutrophil chemotaxis 1.61231625751581e-10 103 116 12 0.103448275862069 0.116504854368932
GO:BP GO:0032103 positive regulation of response to external stimulus 3.94671566495111e-10 513 90 19 0.211111111111111 0.037037037037037
GO:BP GO:0051249 regulation of lymphocyte activation 6.02541720530774e-10 518 139 23 0.165467625899281 0.0444015444015444
GO:BP GO:0050896 response to stimulus 6.17701793637261e-10 9407 132 106 0.803030303030303 0.0112682045285426
GO:BP GO:0046651 lymphocyte proliferation 6.90572455104684e-10 294 139 18 0.129496402877698 0.0612244897959184
GO:BP GO:0032943 mononuclear cell proliferation 8.03102151561921e-10 297 139 18 0.129496402877698 0.0606060606060606
GO:BP GO:0030595 leukocyte chemotaxis 9.52850010397643e-10 227 116 15 0.129310344827586 0.066079295154185
GO:BP GO:0006959 humoral immune response 9.52850010397643e-10 384 96 17 0.177083333333333 0.0442708333333333
GO:BP GO:0002697 regulation of immune effector process 1.14547103430064e-09 461 106 19 0.179245283018868 0.0412147505422994
GO:BP GO:1990266 neutrophil migration 1.27618583245085e-09 124 116 12 0.103448275862069 0.0967741935483871
GO:BP GO:0050670 regulation of lymphocyte proliferation 1.3875984590987e-09 230 139 16 0.115107913669065 0.0695652173913043
GO:BP GO:0071621 granulocyte chemotaxis 1.49397540873336e-09 126 116 12 0.103448275862069 0.0952380952380952
GO:BP GO:0032944 regulation of mononuclear cell proliferation 1.53057418777157e-09 232 139 16 0.115107913669065 0.0689655172413793
GO:BP GO:0030155 regulation of cell adhesion 3.80482146878227e-09 748 118 24 0.203389830508475 0.0320855614973262
GO:BP GO:0051240 positive regulation of multicellular organismal process 4.32398922005641e-09 1455 142 37 0.26056338028169 0.0254295532646048
GO:BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 4.41090023445099e-09 363 97 16 0.164948453608247 0.0440771349862259
GO:BP GO:0002687 positive regulation of leukocyte migration 4.55856492931168e-09 137 118 12 0.101694915254237 0.0875912408759124
GO:BP GO:0070663 regulation of leukocyte proliferation 4.60417651059487e-09 251 139 16 0.115107913669065 0.0637450199203187
GO:BP GO:0072676 lymphocyte migration 1.07510513533455e-08 117 116 11 0.0948275862068965 0.094017094017094
GO:BP GO:0007166 cell surface receptor signaling pathway 1.09851698857093e-08 3210 131 54 0.412213740458015 0.0168224299065421
GO:BP GO:0097530 granulocyte migration 1.09851698857093e-08 151 116 12 0.103448275862069 0.0794701986754967
GO:BP GO:0071674 mononuclear cell migration 1.28897167540202e-08 191 116 13 0.112068965517241 0.0680628272251309
GO:BP GO:0002468 dendritic cell antigen processing and presentation 1.66056843776771e-08 14 3 3 1 0.214285714285714
GO:BP GO:0022409 positive regulation of cell-cell adhesion 2.58576181241287e-08 284 139 16 0.115107913669065 0.0563380281690141
GO:BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 2.58576181241287e-08 99 55 8 0.145454545454545 0.0808080808080808
GO:BP GO:0002449 lymphocyte mediated immunity 2.70870984344531e-08 354 97 15 0.154639175257732 0.0423728813559322
GO:BP GO:0050900 leukocyte migration 3.41661961767119e-08 511 118 19 0.161016949152542 0.0371819960861057
GO:BP GO:0098883 synapse pruning 3.41661961767119e-08 11 83 5 0.0602409638554217 0.454545454545455
GO:BP GO:0050863 regulation of T cell activation 3.74664596634952e-08 337 139 17 0.122302158273381 0.0504451038575668
GO:BP GO:1903037 regulation of leukocyte cell-cell adhesion 3.8707137227235e-08 338 139 17 0.122302158273381 0.0502958579881657
GO:BP GO:0045785 positive regulation of cell adhesion 4.20847546810241e-08 437 139 19 0.136690647482014 0.0434782608695652
GO:BP GO:0032101 regulation of response to external stimulus 4.34504266866033e-08 1051 90 23 0.255555555555556 0.021883920076118
GO:BP GO:0002274 myeloid leukocyte activation 4.49046357452888e-08 667 126 22 0.174603174603175 0.0329835082458771
GO:BP GO:0060326 cell chemotaxis 5.14422810887335e-08 310 116 15 0.129310344827586 0.0483870967741935
GO:BP GO:0022407 regulation of cell-cell adhesion 5.41690377313412e-08 445 139 19 0.136690647482014 0.0426966292134831
GO:BP GO:0097529 myeloid leukocyte migration 6.49433207457722e-08 221 116 13 0.112068965517241 0.0588235294117647
GO:BP GO:0001906 cell killing 9.06517901453306e-08 175 97 11 0.11340206185567 0.0628571428571429
GO:BP GO:0002443 leukocyte mediated immunity 9.06517901453306e-08 877 129 25 0.193798449612403 0.0285062713797035
GO:BP GO:0002696 positive regulation of leukocyte activation 1.01370150019003e-07 412 139 18 0.129496402877698 0.0436893203883495
GO:BP GO:0051239 regulation of multicellular organismal process 1.25030447675085e-07 2861 142 51 0.359154929577465 0.0178259349877665
GO:BP GO:0071310 cellular response to organic substance 1.3453445935336e-07 2776 142 50 0.352112676056338 0.0180115273775216
GO:BP GO:2000403 positive regulation of lymphocyte migration 1.41161087977437e-07 38 116 7 0.0603448275862069 0.184210526315789
GO:BP GO:0050867 positive regulation of cell activation 1.50578089651059e-07 424 139 18 0.129496402877698 0.0424528301886792
GO:BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 1.50578089651059e-07 80 55 7 0.127272727272727 0.0875
GO:BP GO:0070098 chemokine-mediated signaling pathway 1.52188766987411e-07 87 116 9 0.0775862068965517 0.103448275862069
GO:BP GO:0007159 leukocyte cell-cell adhesion 1.52188766987411e-07 375 139 17 0.122302158273381 0.0453333333333333
GO:BP GO:0002699 positive regulation of immune effector process 1.52188766987411e-07 215 129 13 0.10077519379845 0.0604651162790698
GO:BP GO:0010628 positive regulation of gene expression 1.52188766987411e-07 1160 141 30 0.212765957446809 0.0258620689655172
GO:BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 1.66665410390378e-07 241 139 14 0.100719424460432 0.0580912863070539
GO:BP GO:0050870 positive regulation of T cell activation 1.67571629655926e-07 219 7 5 0.714285714285714 0.0228310502283105
GO:BP GO:0048583 regulation of response to stimulus 1.73285994530202e-07 4278 142 65 0.457746478873239 0.0151940158952782
GO:BP GO:0050852 T cell receptor signaling pathway 1.82572109292508e-07 203 139 13 0.0935251798561151 0.0640394088669951
GO:BP GO:0071222 cellular response to lipopolysaccharide 1.90149153071214e-07 200 116 12 0.103448275862069 0.06
GO:BP GO:0048247 lymphocyte chemotaxis 2.00881587049027e-07 63 116 8 0.0689655172413793 0.126984126984127
GO:BP GO:0042098 T cell proliferation 2.00881587049027e-07 205 139 13 0.0935251798561151 0.0634146341463415
GO:BP GO:0002366 leukocyte activation involved in immune response 2.09666068959005e-07 717 129 22 0.170542635658915 0.0306834030683403
GO:BP GO:0010033 response to organic substance 2.21797584616001e-07 3412 131 53 0.404580152671756 0.0155334114888628
GO:BP GO:0002263 cell activation involved in immune response 2.27626221297935e-07 721 129 22 0.170542635658915 0.0305131761442441
GO:BP GO:0071677 positive regulation of mononuclear cell migration 2.4952921088248e-07 65 116 8 0.0689655172413793 0.123076923076923
GO:BP GO:0072678 T cell migration 3.16141963662322e-07 67 116 8 0.0689655172413793 0.119402985074627
GO:BP GO:1990869 cellular response to chemokine 3.47248743765894e-07 97 116 9 0.0775862068965517 0.0927835051546392
GO:BP GO:1990868 response to chemokine 3.47248743765894e-07 97 116 9 0.0775862068965517 0.0927835051546392
GO:BP GO:0071219 cellular response to molecule of bacterial origin 3.70480371547023e-07 214 116 12 0.103448275862069 0.0560747663551402
GO:BP GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 3.74127683213985e-07 13 39 4 0.102564102564103 0.307692307692308
GO:BP GO:0002685 regulation of leukocyte migration 3.77809546148959e-07 211 118 12 0.101694915254237 0.0568720379146919
GO:BP GO:0007155 cell adhesion 4.79040601093777e-07 1492 118 30 0.254237288135593 0.0201072386058981
GO:BP GO:0022610 biological adhesion 5.19352150632689e-07 1499 118 30 0.254237288135593 0.0200133422281521
GO:BP GO:0050866 negative regulation of cell activation 5.28870374487887e-07 211 122 12 0.0983606557377049 0.0568720379146919
GO:BP GO:0002683 negative regulation of immune system process 6.22835253424238e-07 420 122 16 0.131147540983607 0.0380952380952381
GO:BP GO:0001916 positive regulation of T cell mediated cytotoxicity 6.47768218904173e-07 26 22 4 0.181818181818182 0.153846153846154
GO:BP GO:0034612 response to tumor necrosis factor 8.87933536748612e-07 331 118 14 0.11864406779661 0.0422960725075529
GO:BP GO:0150146 cell junction disassembly 9.13200092252707e-07 21 83 5 0.0602409638554217 0.238095238095238
GO:BP GO:0006874 cellular calcium ion homeostasis 1.02834721766088e-06 460 116 16 0.137931034482759 0.0347826086956522
GO:BP GO:0006875 cellular metal ion homeostasis 1.07167288228517e-06 593 116 18 0.155172413793103 0.03035413153457
GO:BP GO:0071216 cellular response to biotic stimulus 1.0724332549571e-06 238 116 12 0.103448275862069 0.0504201680672269
GO:BP GO:0055065 metal ion homeostasis 1.16287997808846e-06 667 116 19 0.163793103448276 0.0284857571214393
GO:BP GO:0019725 cellular homeostasis 1.35060359059508e-06 981 116 23 0.198275862068966 0.0234454638124363
GO:BP GO:0055074 calcium ion homeostasis 1.41073454331894e-06 472 116 16 0.137931034482759 0.0338983050847458
GO:BP GO:0002695 negative regulation of leukocyte activation 1.45694976987772e-06 188 122 11 0.0901639344262295 0.0585106382978723
GO:BP GO:0002521 leukocyte differentiation 1.52174733965533e-06 550 142 19 0.133802816901408 0.0345454545454545
GO:BP GO:0050921 positive regulation of chemotaxis 1.52386859494693e-06 141 128 10 0.078125 0.0709219858156028
GO:BP GO:0006968 cellular defense response 1.5503299169818e-06 53 122 7 0.0573770491803279 0.132075471698113
GO:BP GO:0002237 response to molecule of bacterial origin 1.58616231898814e-06 361 97 13 0.134020618556701 0.03601108033241
GO:BP GO:0051251 positive regulation of lymphocyte activation 1.59226377735454e-06 365 7 5 0.714285714285714 0.0136986301369863
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 1.8610092457608e-06 512 139 18 0.129496402877698 0.03515625
GO:BP GO:0001914 regulation of T cell mediated cytotoxicity 1.99135710565944e-06 35 22 4 0.181818181818182 0.114285714285714
GO:BP GO:0002764 immune response-regulating signaling pathway 2.00212208127438e-06 515 139 18 0.129496402877698 0.0349514563106796
GO:BP GO:0051250 negative regulation of lymphocyte activation 2.35528700062902e-06 156 122 10 0.0819672131147541 0.0641025641025641
GO:BP GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 2.35528700062902e-06 75 55 6 0.109090909090909 0.08
GO:BP GO:0071356 cellular response to tumor necrosis factor 2.35528700062902e-06 306 118 13 0.110169491525424 0.042483660130719
GO:BP GO:0030217 T cell differentiation 2.44831624400916e-06 260 139 13 0.0935251798561151 0.05
GO:BP GO:0042129 regulation of T cell proliferation 2.578308343524e-06 176 139 11 0.079136690647482 0.0625
GO:BP GO:0072503 cellular divalent inorganic cation homeostasis 2.578308343524e-06 497 116 16 0.137931034482759 0.0321931589537223
GO:BP GO:0045582 positive regulation of T cell differentiation 2.77107358052487e-06 91 3 3 1 0.032967032967033
GO:BP GO:0050671 positive regulation of lymphocyte proliferation 3.01112410190179e-06 141 139 10 0.0719424460431655 0.0709219858156028
GO:BP GO:0002690 positive regulation of leukocyte chemotaxis 3.17508319953652e-06 93 116 8 0.0689655172413793 0.0860215053763441
GO:BP GO:0032946 positive regulation of mononuclear cell proliferation 3.17508319953652e-06 142 139 10 0.0719424460431655 0.0704225352112676
GO:BP GO:0002757 immune response-activating signal transduction 3.28314216444674e-06 477 139 17 0.122302158273381 0.0356394129979036
GO:BP GO:0002429 immune response-activating cell surface receptor signaling pathway 3.28314216444674e-06 477 139 17 0.122302158273381 0.0356394129979036
GO:BP GO:2000401 regulation of lymphocyte migration 3.28314216444674e-06 63 116 7 0.0603448275862069 0.111111111111111
GO:BP GO:0001913 T cell mediated cytotoxicity 3.81825375600739e-06 42 22 4 0.181818181818182 0.0952380952380952
GO:BP GO:0045621 positive regulation of lymphocyte differentiation 3.86276322876764e-06 104 3 3 1 0.0288461538461538
GO:BP GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib 3.86276322876764e-06 6 39 3 0.0769230769230769 0.5
GO:BP GO:0072507 divalent inorganic cation homeostasis 3.91348178783955e-06 516 116 16 0.137931034482759 0.0310077519379845
GO:BP GO:0050851 antigen receptor-mediated signaling pathway 4.05774499278143e-06 323 139 14 0.100719424460432 0.043343653250774
GO:BP GO:0051651 maintenance of location in cell 4.45936832866075e-06 223 93 10 0.10752688172043 0.0448430493273543
GO:BP GO:0002705 positive regulation of leukocyte mediated immunity 4.50828336814096e-06 122 129 9 0.0697674418604651 0.0737704918032787
GO:BP GO:0002286 T cell activation involved in immune response 4.68538925493983e-06 112 3 3 1 0.0267857142857143
GO:BP GO:0032496 response to lipopolysaccharide 5.1032437239137e-06 338 97 12 0.123711340206186 0.0355029585798817
GO:BP GO:1903131 mononuclear cell differentiation 5.38541692740287e-06 430 142 16 0.112676056338028 0.0372093023255814
GO:BP GO:0030003 cellular cation homeostasis 5.38541692740287e-06 673 116 18 0.155172413793103 0.0267459138187221
GO:BP GO:0030098 lymphocyte differentiation 5.38541692740287e-06 376 142 15 0.105633802816901 0.0398936170212766
GO:BP GO:0055080 cation homeostasis 5.51488582383661e-06 750 116 19 0.163793103448276 0.0253333333333333
GO:BP GO:0016064 immunoglobulin mediated immune response 5.74191534896488e-06 223 96 10 0.104166666666667 0.0448430493273543
GO:BP GO:0002711 positive regulation of T cell mediated immunity 5.98064071637459e-06 48 22 4 0.181818181818182 0.0833333333333333
GO:BP GO:0070665 positive regulation of leukocyte proliferation 6.28555707905518e-06 155 139 10 0.0719424460431655 0.0645161290322581
GO:BP GO:0031341 regulation of cell killing 6.28555707905518e-06 93 129 8 0.062015503875969 0.0860215053763441
GO:BP GO:0019724 B cell mediated immunity 6.34481706868427e-06 226 96 10 0.104166666666667 0.0442477876106195
GO:BP GO:0098771 inorganic ion homeostasis 6.64881142224377e-06 761 116 19 0.163793103448276 0.0249671484888305
GO:BP GO:0055082 cellular chemical homeostasis 6.76493734685333e-06 841 116 20 0.172413793103448 0.0237812128418549
GO:BP GO:0006873 cellular ion homeostasis 6.89622802200569e-06 687 116 18 0.155172413793103 0.0262008733624454
GO:BP GO:0070887 cellular response to chemical stimulus 7.06871683335184e-06 3393 142 52 0.366197183098592 0.0153256704980843
GO:BP GO:0001912 positive regulation of leukocyte mediated cytotoxicity 7.31631511617742e-06 51 22 4 0.181818181818182 0.0784313725490196
GO:BP GO:0048518 positive regulation of biological process 7.99260995404502e-06 6363 142 79 0.556338028169014 0.0124155272670124
GO:BP GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 8.89573906073492e-06 96 30 5 0.166666666666667 0.0520833333333333
GO:BP GO:0051928 positive regulation of calcium ion transport 9.33039742149598e-06 125 139 9 0.0647482014388489 0.072
GO:BP GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane 9.53915794815363e-06 6 55 3 0.0545454545454545 0.5
GO:BP GO:0045580 regulation of T cell differentiation 1.04420966762972e-05 152 3 3 1 0.0197368421052632
GO:BP GO:1901623 regulation of lymphocyte chemotaxis 1.04545508770612e-05 26 116 5 0.0431034482758621 0.192307692307692
GO:BP GO:0002821 positive regulation of adaptive immune response 1.10897522396033e-05 101 30 5 0.166666666666667 0.0495049504950495
GO:BP GO:1903708 positive regulation of hemopoiesis 1.12678575405448e-05 157 3 3 1 0.0191082802547771
GO:BP GO:1902107 positive regulation of leukocyte differentiation 1.12678575405448e-05 157 3 3 1 0.0191082802547771
GO:BP GO:0002819 regulation of adaptive immune response 1.13185736909256e-05 167 139 10 0.0719424460431655 0.0598802395209581
GO:BP GO:0071675 regulation of mononuclear cell migration 1.13185736909256e-05 113 116 8 0.0689655172413793 0.0707964601769911
GO:BP GO:0031343 positive regulation of cell killing 1.22696644729909e-05 59 22 4 0.181818181818182 0.0677966101694915
GO:BP GO:0002708 positive regulation of lymphocyte mediated immunity 1.23631332907872e-05 104 30 5 0.166666666666667 0.0480769230769231
GO:BP GO:0051924 regulation of calcium ion transport 1.29067794174277e-05 259 139 12 0.0863309352517986 0.0463320463320463
GO:BP GO:0006935 chemotaxis 1.32937889170926e-05 653 128 18 0.140625 0.0275650842266462
GO:BP GO:0001774 microglial cell activation 1.34525469907592e-05 55 106 6 0.0566037735849057 0.109090909090909
GO:BP GO:0019730 antimicrobial humoral response 1.34525469907592e-05 145 93 8 0.0860215053763441 0.0551724137931034
GO:BP GO:0042330 taxis 1.39832454924162e-05 656 128 18 0.140625 0.0274390243902439
GO:BP GO:0050801 ion homeostasis 1.42956454019941e-05 808 116 19 0.163793103448276 0.0235148514851485
GO:BP GO:0010818 T cell chemotaxis 1.42956454019941e-05 28 116 5 0.0431034482758621 0.178571428571429
GO:BP GO:0031349 positive regulation of defense response 1.51579460360404e-05 362 141 14 0.099290780141844 0.0386740331491713
GO:BP GO:0001910 regulation of leukocyte mediated cytotoxicity 1.56619280191987e-05 74 129 7 0.0542635658914729 0.0945945945945946
GO:BP GO:0045619 regulation of lymphocyte differentiation 1.57587285286556e-05 180 3 3 1 0.0166666666666667
GO:BP GO:0002688 regulation of leukocyte chemotaxis 1.65774452945555e-05 120 116 8 0.0689655172413793 0.0666666666666667
GO:BP GO:0002285 lymphocyte activation involved in immune response 1.70737571899762e-05 190 129 10 0.0775193798449612 0.0526315789473684
GO:BP GO:0010959 regulation of metal ion transport 1.73348049258452e-05 268 139 12 0.0863309352517986 0.0447761194029851
GO:BP GO:0050730 regulation of peptidyl-tyrosine phosphorylation 1.79394265620472e-05 269 139 12 0.0863309352517986 0.0446096654275093
GO:BP GO:0051235 maintenance of location 1.91911304065158e-05 337 93 11 0.118279569892473 0.0326409495548961
GO:BP GO:0042102 positive regulation of T cell proliferation 2.11625491348218e-05 104 139 8 0.0575539568345324 0.0769230769230769
GO:BP GO:2000406 positive regulation of T cell migration 2.26331338122158e-05 31 116 5 0.0431034482758621 0.161290322580645
GO:BP GO:0032609 interferon-gamma production 2.54046021677567e-05 115 129 8 0.062015503875969 0.0695652173913043
GO:BP GO:0002709 regulation of T cell mediated immunity 2.69788689235502e-05 74 22 4 0.181818181818182 0.0540540540540541
GO:BP GO:0042127 regulation of cell population proliferation 2.92025180838446e-05 1774 142 33 0.232394366197183 0.0186020293122886
GO:BP GO:0002703 regulation of leukocyte mediated immunity 3.17990773313119e-05 205 129 10 0.0775193798449612 0.0487804878048781
GO:BP GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 3.51150954405783e-05 42 93 5 0.0537634408602151 0.119047619047619
GO:BP GO:0071396 cellular response to lipid 3.53464782131776e-05 578 97 14 0.144329896907216 0.0242214532871972
GO:BP GO:0002475 antigen processing and presentation via MHC class Ib 3.8284089151031e-05 13 39 3 0.0769230769230769 0.230769230769231
GO:BP GO:0048878 chemical homeostasis 4.03887344841827e-05 1229 116 23 0.198275862068966 0.0187144019528072
GO:BP GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 4.43895577589397e-05 198 139 10 0.0719424460431655 0.0505050505050505
GO:BP GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 5.38063394010826e-05 81 93 6 0.0645161290322581 0.0740740740740741
GO:BP GO:0042116 macrophage activation 5.39931613161021e-05 110 106 7 0.0660377358490566 0.0636363636363636
GO:BP GO:0098609 cell-cell adhesion 5.50290990464668e-05 894 116 19 0.163793103448276 0.0212527964205817
GO:BP GO:1902105 regulation of leukocyte differentiation 5.68009295341572e-05 288 3 3 1 0.0104166666666667
GO:BP GO:0007154 cell communication 5.77666792596758e-05 6829 131 75 0.572519083969466 0.0109825743154195
GO:BP GO:0007165 signal transduction 5.77666792596758e-05 6309 131 71 0.541984732824427 0.0112537644634649
GO:BP GO:0002833 positive regulation of response to biotic stimulus 5.90060843525254e-05 250 141 11 0.0780141843971631 0.044
GO:BP GO:0032102 negative regulation of response to external stimulus 5.92856723040024e-05 406 88 11 0.125 0.0270935960591133
GO:BP GO:0002520 immune system development 6.00491328131513e-05 1020 142 23 0.161971830985915 0.0225490196078431
GO:BP GO:0010524 positive regulation of calcium ion transport into cytosol 6.00491328131513e-05 56 139 6 0.0431654676258993 0.107142857142857
GO:BP GO:0002548 monocyte chemotaxis 6.03841231877266e-05 67 116 6 0.0517241379310345 0.0895522388059701
GO:BP GO:0002706 regulation of lymphocyte mediated immunity 6.18193258045122e-05 151 30 5 0.166666666666667 0.033112582781457
GO:BP GO:0002831 regulation of response to biotic stimulus 6.18193258045122e-05 415 141 14 0.099290780141844 0.0337349397590361
GO:BP GO:0031347 regulation of defense response 6.30121968514002e-05 704 85 14 0.164705882352941 0.0198863636363636
GO:BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.33046819480261e-05 152 30 5 0.166666666666667 0.0328947368421053
GO:BP GO:0050920 regulation of chemotaxis 6.33046819480261e-05 226 128 10 0.078125 0.0442477876106195
GO:BP GO:0051208 sequestering of calcium ion 6.33996744281067e-05 130 93 7 0.0752688172043011 0.0538461538461538
GO:BP GO:0033634 positive regulation of cell-cell adhesion mediated by integrin 6.71208647783483e-05 6 116 3 0.0258620689655172 0.5
GO:BP GO:2000503 positive regulation of natural killer cell chemotaxis 6.71208647783483e-05 6 116 3 0.0258620689655172 0.5
GO:BP GO:0043410 positive regulation of MAPK cascade 6.84499331000975e-05 539 142 16 0.112676056338028 0.0296846011131725
GO:BP GO:0044403 biological process involved in symbiotic interaction 6.93906223582453e-05 1001 97 18 0.185567010309278 0.017982017982018
GO:BP GO:0002456 T cell mediated immunity 7.18387577231769e-05 98 22 4 0.181818181818182 0.0408163265306122
GO:BP GO:1902533 positive regulation of intracellular signal transduction 7.47970264698352e-05 1037 142 23 0.161971830985915 0.0221793635486982
GO:BP GO:0048245 eosinophil chemotaxis 7.48939655666922e-05 19 116 4 0.0344827586206897 0.210526315789474
GO:BP GO:0006953 acute-phase response 7.60175046019657e-05 50 43 4 0.0930232558139535 0.08
GO:BP GO:0008283 cell population proliferation 8.24007711743751e-05 2054 142 35 0.246478873239437 0.0170399221032132
GO:BP GO:0042221 response to chemical 9.08785281864173e-05 4781 131 58 0.442748091603053 0.0121313532733738
GO:BP GO:0007204 positive regulation of cytosolic calcium ion concentration 9.08785281864173e-05 325 115 11 0.0956521739130435 0.0338461538461538
GO:BP GO:0002526 acute inflammatory response 9.18847394612616e-05 114 43 5 0.116279069767442 0.043859649122807
GO:BP GO:0045089 positive regulation of innate immune response 9.50504762179427e-05 216 141 10 0.0709219858156028 0.0462962962962963
GO:BP GO:0032649 regulation of interferon-gamma production 9.50504762179427e-05 110 7 3 0.428571428571429 0.0272727272727273
GO:BP GO:0036230 granulocyte activation 9.60963870318083e-05 504 122 14 0.114754098360656 0.0277777777777778
GO:BP GO:0070374 positive regulation of ERK1 and ERK2 cascade 9.62597415583202e-05 215 142 10 0.0704225352112676 0.0465116279069767
GO:BP GO:0001909 leukocyte mediated cytotoxicity 9.72487420849348e-05 107 22 4 0.181818181818182 0.0373831775700935
GO:BP GO:0023052 signaling 0.000101761329821248 6810 131 74 0.564885496183206 0.0108663729809104
GO:BP GO:2000404 regulation of T cell migration 0.000108911932696136 44 116 5 0.0431034482758621 0.113636363636364
GO:BP GO:0140131 positive regulation of lymphocyte chemotaxis 0.000108911932696136 21 116 4 0.0344827586206897 0.19047619047619
GO:BP GO:0042592 homeostatic process 0.000113324338925893 1981 102 27 0.264705882352941 0.0136294800605755
GO:BP GO:1901214 regulation of neuron death 0.000113324338925893 323 142 12 0.0845070422535211 0.0371517027863777
GO:BP GO:0016032 viral process 0.000116483477656483 942 97 17 0.175257731958763 0.0180467091295117
GO:BP GO:0006887 exocytosis 0.000116521386183138 904 122 19 0.155737704918033 0.0210176991150442
GO:BP GO:0001961 positive regulation of cytokine-mediated signaling pathway 0.000118460324479774 50 104 5 0.0480769230769231 0.1
GO:BP GO:0018108 peptidyl-tyrosine phosphorylation 0.000130025372939355 385 142 13 0.0915492957746479 0.0337662337662338
GO:BP GO:0030097 hemopoiesis 0.000135387977766988 928 142 21 0.147887323943662 0.0226293103448276
GO:BP GO:0030335 positive regulation of cell migration 0.000135661254713351 567 128 15 0.1171875 0.0264550264550265
GO:BP GO:0007584 response to nutrient 0.000135661254713351 182 139 9 0.0647482014388489 0.0494505494505494
GO:BP GO:0032940 secretion by cell 0.000136892923760405 1364 122 24 0.19672131147541 0.0175953079178886
GO:BP GO:0018212 peptidyl-tyrosine modification 0.000138183315929335 388 142 13 0.0915492957746479 0.0335051546391753
GO:BP GO:0002720 positive regulation of cytokine production involved in immune response 0.000146131687301897 54 48 4 0.0833333333333333 0.0740740740740741
GO:BP GO:0072677 eosinophil migration 0.000148393443164852 23 116 4 0.0344827586206897 0.173913043478261
GO:BP GO:1903706 regulation of hemopoiesis 0.000148393443164852 424 3 3 1 0.00707547169811321
GO:BP GO:2000501 regulation of natural killer cell chemotaxis 0.00016032646532391 8 116 3 0.0258620689655172 0.375
GO:BP GO:0043299 leukocyte degranulation 0.000169829142484193 535 122 14 0.114754098360656 0.0261682242990654
GO:BP GO:0051241 negative regulation of multicellular organismal process 0.000187011737107999 1160 83 17 0.204819277108434 0.0146551724137931
GO:BP GO:0051050 positive regulation of transport 0.000193834724185619 923 93 16 0.172043010752688 0.0173347778981582
GO:BP GO:0051480 regulation of cytosolic calcium ion concentration 0.000207477427987809 360 115 11 0.0956521739130435 0.0305555555555556
GO:BP GO:2000147 positive regulation of cell motility 0.000208717693624685 591 128 15 0.1171875 0.0253807106598985
GO:BP GO:0060760 positive regulation of response to cytokine stimulus 0.000209088905224289 57 104 5 0.0480769230769231 0.087719298245614
GO:BP GO:0046903 secretion 0.000209679475351876 1501 122 25 0.204918032786885 0.016655562958028
GO:BP GO:2000026 regulation of multicellular organismal development 0.000212436374831884 1447 142 27 0.190140845070423 0.0186592950932965
GO:BP GO:0045055 regulated exocytosis 0.000224552996869216 785 122 17 0.139344262295082 0.021656050955414
GO:BP GO:0048534 hematopoietic or lymphoid organ development 0.0002278284626269 966 142 21 0.147887323943662 0.0217391304347826
GO:BP GO:0048522 positive regulation of cellular process 0.00022821976826506 5757 142 69 0.485915492957746 0.0119854090672225
GO:BP GO:0008219 cell death 0.000233452105045454 2292 135 35 0.259259259259259 0.0152705061082024
GO:BP GO:0002573 myeloid leukocyte differentiation 0.000236990070875175 213 72 7 0.0972222222222222 0.0328638497652582
GO:BP GO:0140352 export from cell 0.000239393128538406 1418 122 24 0.19672131147541 0.0169252468265162
GO:BP GO:0060142 regulation of syncytium formation by plasma membrane fusion 0.000250163762693876 27 114 4 0.0350877192982456 0.148148148148148
GO:BP GO:0050672 negative regulation of lymphocyte proliferation 0.000250163762693876 85 122 6 0.0491803278688525 0.0705882352941176
GO:BP GO:0002702 positive regulation of production of molecular mediator of immune response 0.000254564148238938 100 104 6 0.0576923076923077 0.06
GO:BP GO:0051272 positive regulation of cellular component movement 0.000254912742316384 604 128 15 0.1171875 0.0248344370860927
GO:BP GO:0040017 positive regulation of locomotion 0.000263160012168581 606 128 15 0.1171875 0.0247524752475248
GO:BP GO:0032945 negative regulation of mononuclear cell proliferation 0.000263185611795288 86 122 6 0.0491803278688525 0.0697674418604651
GO:BP GO:0071347 cellular response to interleukin-1 0.000265127929036488 185 116 8 0.0689655172413793 0.0432432432432432
GO:BP GO:0032908 regulation of transforming growth factor beta1 production 0.000267907719229199 13 83 3 0.036144578313253 0.230769230769231
GO:BP GO:0016322 neuron remodeling 0.000267907719229199 13 83 3 0.036144578313253 0.230769230769231
GO:BP GO:0033993 response to lipid 0.000286774671849511 918 97 16 0.164948453608247 0.0174291938997821
GO:BP GO:1903038 negative regulation of leukocyte cell-cell adhesion 0.000295127263049283 142 23 4 0.173913043478261 0.028169014084507
GO:BP GO:0002920 regulation of humoral immune response 0.000297950577576903 133 81 6 0.0740740740740741 0.0451127819548872
GO:BP GO:0035747 natural killer cell chemotaxis 0.000305364505121983 10 116 3 0.0258620689655172 0.3
GO:BP GO:0045088 regulation of innate immune response 0.000313567770697924 309 141 11 0.0780141843971631 0.0355987055016181
GO:BP GO:0001934 positive regulation of protein phosphorylation 0.000316743342332661 840 142 19 0.133802816901408 0.0226190476190476
GO:BP GO:0070997 neuron death 0.000316743342332661 365 142 12 0.0845070422535211 0.0328767123287671
GO:BP GO:0042119 neutrophil activation 0.000317641625884282 498 122 13 0.10655737704918 0.0261044176706827
GO:BP GO:0032905 transforming growth factor beta1 production 0.00032841392016741 14 83 3 0.036144578313253 0.214285714285714
GO:BP GO:0070372 regulation of ERK1 and ERK2 cascade 0.000328694085597893 309 142 11 0.0774647887323944 0.0355987055016181
GO:BP GO:0012501 programmed cell death 0.000333938400240668 2143 135 33 0.244444444444444 0.0153989734017732
GO:BP GO:0001932 regulation of protein phosphorylation 0.00033440030961903 1240 142 24 0.169014084507042 0.0193548387096774
GO:BP GO:0006957 complement activation, alternative pathway 0.000343959933721071 17 69 3 0.0434782608695652 0.176470588235294
GO:BP GO:0070664 negative regulation of leukocyte proliferation 0.000363072741041229 92 122 6 0.0491803278688525 0.0652173913043478
GO:BP GO:1904427 positive regulation of calcium ion transmembrane transport 0.000384859952882552 74 93 5 0.0537634408602151 0.0675675675675676
GO:BP GO:0033632 regulation of cell-cell adhesion mediated by integrin 0.000394646001735071 11 116 3 0.0258620689655172 0.272727272727273
GO:BP GO:0051209 release of sequestered calcium ion into cytosol 0.000394646001735071 123 93 6 0.0645161290322581 0.0487804878048781
GO:BP GO:0009967 positive regulation of signal transduction 0.000394646001735071 1598 142 28 0.197183098591549 0.0175219023779725
GO:BP GO:0010647 positive regulation of cell communication 0.000396488783381979 1777 142 30 0.211267605633803 0.0168823860438942
GO:BP GO:0051283 negative regulation of sequestering of calcium ion 0.000406858086625543 124 93 6 0.0645161290322581 0.0483870967741935
GO:BP GO:0023056 positive regulation of signaling 0.000410644521132499 1782 142 30 0.211267605633803 0.0168350168350168
GO:BP GO:0045058 T cell selection 0.00041371531386767 51 139 5 0.0359712230215827 0.0980392156862745
GO:BP GO:0051282 regulation of sequestering of calcium ion 0.000438933401635026 126 93 6 0.0645161290322581 0.0476190476190476
GO:BP GO:0006956 complement activation 0.000450171869825343 180 96 7 0.0729166666666667 0.0388888888888889
GO:BP GO:0006915 apoptotic process 0.000461177569743949 1990 135 31 0.22962962962963 0.0155778894472362
GO:BP GO:0009991 response to extracellular stimulus 0.00047188068689765 512 142 14 0.0985915492957746 0.02734375
GO:BP GO:0070371 ERK1 and ERK2 cascade 0.000529988828040629 329 142 11 0.0774647887323944 0.033434650455927
GO:BP GO:0007568 aging 0.000529988828040629 329 142 11 0.0774647887323944 0.033434650455927
GO:BP GO:0032612 interleukin-1 production 0.000533277462049593 126 141 7 0.049645390070922 0.0555555555555556
GO:BP GO:0043408 regulation of MAPK cascade 0.000537055145020446 730 142 17 0.119718309859155 0.0232876712328767
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.000541745832441457 3483 142 47 0.330985915492958 0.0134941142693081
GO:BP GO:0006457 protein folding 0.000544289996534857 225 55 6 0.109090909090909 0.0266666666666667
GO:BP GO:0007162 negative regulation of cell adhesion 0.000578383908315115 304 104 9 0.0865384615384615 0.0296052631578947
GO:BP GO:0080134 regulation of response to stress 0.000641006628385778 1443 90 19 0.211111111111111 0.0131670131670132
GO:BP GO:0002440 production of molecular mediator of immune response 0.000649652542493832 189 22 4 0.181818181818182 0.0211640211640212
GO:BP GO:0070555 response to interleukin-1 0.000651062220103205 215 116 8 0.0689655172413793 0.0372093023255814
GO:BP GO:0002718 regulation of cytokine production involved in immune response 0.000663685625766714 85 48 4 0.0833333333333333 0.0470588235294118
GO:BP GO:0045059 positive thymic T cell selection 0.000664965150826062 14 110 3 0.0272727272727273 0.214285714285714
GO:BP GO:0016477 cell migration 0.000664965150826062 1649 128 26 0.203125 0.015767131594906
GO:BP GO:0030449 regulation of complement activation 0.000665842214312768 110 72 5 0.0694444444444444 0.0454545454545455
GO:BP GO:0051279 regulation of release of sequestered calcium ion into cytosol 0.000665842214312768 85 93 5 0.0537634408602151 0.0588235294117647
GO:BP GO:0032732 positive regulation of interleukin-1 production 0.000665842214312768 65 122 5 0.040983606557377 0.0769230769230769
GO:BP GO:0050869 negative regulation of B cell activation 0.000675978891329779 34 122 4 0.0327868852459016 0.117647058823529
GO:BP GO:0002275 myeloid cell activation involved in immune response 0.000709820703865926 547 122 13 0.10655737704918 0.0237659963436929
GO:BP GO:0002444 myeloid leukocyte mediated immunity 0.000761692470934663 551 122 13 0.10655737704918 0.0235934664246824
GO:BP GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 0.000780477888191014 93 142 6 0.0422535211267606 0.0645161290322581
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.000783164950102457 1227 98 18 0.183673469387755 0.0146699266503667
GO:BP GO:1901700 response to oxygen-containing compound 0.000801013615279898 1739 103 23 0.223300970873786 0.0132259919493962
GO:BP GO:0022408 negative regulation of cell-cell adhesion 0.000814306582945249 194 23 4 0.173913043478261 0.0206185567010309
GO:BP GO:0043312 neutrophil degranulation 0.000847749440640209 482 122 12 0.0983606557377049 0.024896265560166
GO:BP GO:0050850 positive regulation of calcium-mediated signaling 0.0008479571568311 32 139 4 0.0287769784172662 0.125
GO:BP GO:0097553 calcium ion transmembrane import into cytosol 0.000853698160766528 145 93 6 0.0645161290322581 0.0413793103448276
GO:BP GO:0033627 cell adhesion mediated by integrin 0.000875140107032522 73 116 5 0.0431034482758621 0.0684931506849315
GO:BP GO:0032729 positive regulation of interferon-gamma production 0.000888342859420335 66 129 5 0.0387596899224806 0.0757575757575758
GO:BP GO:0002283 neutrophil activation involved in immune response 0.000888342859420335 485 122 12 0.0983606557377049 0.0247422680412371
GO:BP GO:0046718 viral entry into host cell 0.000896401619918309 141 139 7 0.0503597122302158 0.049645390070922
GO:BP GO:0031667 response to nutrient levels 0.000905141352549695 482 142 13 0.0915492957746479 0.0269709543568465
GO:BP GO:0043922 negative regulation by host of viral transcription 0.00090542136432182 15 116 3 0.0258620689655172 0.2
GO:BP GO:0002791 regulation of peptide secretion 0.00090542136432182 325 6 3 0.5 0.00923076923076923
GO:BP GO:0048246 macrophage chemotaxis 0.000906148605638148 39 116 4 0.0344827586206897 0.102564102564103
GO:BP GO:0009893 positive regulation of metabolic process 0.000908659184273814 3783 142 49 0.345070422535211 0.0129526830557758
GO:BP GO:0002367 cytokine production involved in immune response 0.000908659184273814 94 48 4 0.0833333333333333 0.0425531914893617
GO:BP GO:0006816 calcium ion transport 0.000914842473548703 436 116 11 0.0948275862068965 0.0252293577981651
GO:BP GO:0043269 regulation of ion transport 0.000914842473548703 1379 97 19 0.195876288659794 0.0137781000725163
GO:BP GO:0045597 positive regulation of cell differentiation 0.000923029497875717 879 3 3 1 0.00341296928327645
GO:BP GO:0042327 positive regulation of phosphorylation 0.000933102320047825 927 142 19 0.133802816901408 0.0204962243797195
GO:BP GO:0042325 regulation of phosphorylation 0.000952843054761921 1431 142 25 0.176056338028169 0.0174703004891684
GO:BP GO:0050918 positive chemotaxis 0.000953971601106629 68 128 5 0.0390625 0.0735294117647059
GO:BP GO:0050777 negative regulation of immune response 0.000979852272453337 157 56 5 0.0892857142857143 0.0318471337579618
GO:BP GO:0002761 regulation of myeloid leukocyte differentiation 0.00102579171392101 123 72 5 0.0694444444444444 0.040650406504065
GO:BP GO:0002446 neutrophil mediated immunity 0.00106205354469638 497 122 12 0.0983606557377049 0.0241448692152917
GO:BP GO:0031348 negative regulation of defense response 0.00106511304087564 246 83 7 0.0843373493975904 0.0284552845528455
GO:BP GO:0045429 positive regulation of nitric oxide biosynthetic process 0.00107754838717417 45 106 4 0.0377358490566038 0.0888888888888889
GO:BP GO:0043270 positive regulation of ion transport 0.00110252955282298 694 116 14 0.120689655172414 0.0201729106628242
GO:BP GO:0010941 regulation of cell death 0.0011425380157661 1720 142 28 0.197183098591549 0.0162790697674419
GO:BP GO:0002888 positive regulation of myeloid leukocyte mediated immunity 0.0011625498010023 18 106 3 0.0283018867924528 0.166666666666667
GO:BP GO:1904407 positive regulation of nitric oxide metabolic process 0.00116380353187445 46 106 4 0.0377358490566038 0.0869565217391304
GO:BP GO:0043368 positive T cell selection 0.00116560186749061 38 129 4 0.0310077519379845 0.105263157894737
GO:BP GO:2000145 regulation of cell motility 0.00118458168829545 1061 97 16 0.164948453608247 0.0150801131008483
GO:BP GO:0032652 regulation of interleukin-1 production 0.00118889656143261 119 122 6 0.0491803278688525 0.0504201680672269
GO:BP GO:0065003 protein-containing complex assembly 0.00123014966190049 1680 19 8 0.421052631578947 0.00476190476190476
GO:BP GO:0051674 localization of cell 0.00123099737241852 1828 128 27 0.2109375 0.0147702407002188
GO:BP GO:0048870 cell motility 0.00123099737241852 1828 128 27 0.2109375 0.0147702407002188
GO:BP GO:0010819 regulation of T cell chemotaxis 0.00124149559709267 17 116 3 0.0258620689655172 0.176470588235294
GO:BP GO:0033631 cell-cell adhesion mediated by integrin 0.00124149559709267 17 116 3 0.0258620689655172 0.176470588235294
GO:BP GO:0042742 defense response to bacterium 0.00125954533517453 349 81 8 0.0987654320987654 0.0229226361031519
GO:BP GO:0010522 regulation of calcium ion transport into cytosol 0.00126300863965128 106 139 6 0.0431654676258993 0.0566037735849057
GO:BP GO:0050793 regulation of developmental process 0.00134218472986748 2605 142 37 0.26056338028169 0.0142034548944338
GO:BP GO:0044409 entry into host 0.00135066443701157 154 97 6 0.0618556701030928 0.038961038961039
GO:BP GO:0002455 humoral immune response mediated by circulating immunoglobulin 0.00136566610985606 156 96 6 0.0625 0.0384615384615385
GO:BP GO:0008284 positive regulation of cell population proliferation 0.00137260426445971 982 139 19 0.136690647482014 0.0193482688391039
GO:BP GO:0051049 regulation of transport 0.00137971620547376 1809 97 22 0.22680412371134 0.0121614151464898
GO:BP GO:0032611 interleukin-1 beta production 0.00141448674372403 107 141 6 0.0425531914893617 0.0560747663551402
GO:BP GO:0006826 iron ion transport 0.00149235352595723 80 26 3 0.115384615384615 0.0375
GO:BP GO:0060402 calcium ion transport into cytosol 0.00153493693491265 165 93 6 0.0645161290322581 0.0363636363636364
GO:BP GO:0002700 regulation of production of molecular mediator of immune response 0.00156410755766034 148 104 6 0.0576923076923077 0.0405405405405405
GO:BP GO:1901739 regulation of myoblast fusion 0.00160926964909066 19 114 3 0.0263157894736842 0.157894736842105
GO:BP GO:0030334 regulation of cell migration 0.001689848232946 999 128 18 0.140625 0.018018018018018
GO:BP GO:0002544 chronic inflammatory response 0.001689848232946 19 116 3 0.0258620689655172 0.157894736842105
GO:BP GO:0002790 peptide secretion 0.00173063448252085 421 6 3 0.5 0.00712589073634204
GO:BP GO:0040012 regulation of locomotion 0.00175481565548409 1104 97 16 0.164948453608247 0.0144927536231884
GO:BP GO:0045765 regulation of angiogenesis 0.00184448697931954 358 106 9 0.0849056603773585 0.0251396648044693
GO:BP GO:0043085 positive regulation of catalytic activity 0.00191740135199789 1418 142 24 0.169014084507042 0.0169252468265162
GO:BP GO:0090026 positive regulation of monocyte chemotaxis 0.00194034262381984 20 116 3 0.0258620689655172 0.15
GO:BP GO:0031401 positive regulation of protein modification process 0.00195120444507238 1074 142 20 0.140845070422535 0.0186219739292365
GO:BP GO:0009615 response to virus 0.00201054864789509 364 129 10 0.0775193798449612 0.0274725274725275
GO:BP GO:1901342 regulation of vasculature development 0.00204394294677354 364 106 9 0.0849056603773585 0.0247252747252747
GO:BP GO:0030099 myeloid cell differentiation 0.00206660027766453 428 72 8 0.111111111111111 0.0186915887850467
GO:BP GO:0043523 regulation of neuron apoptotic process 0.00217881251239575 216 142 8 0.0563380281690141 0.037037037037037
GO:BP GO:0045061 thymic T cell selection 0.00217881251239575 22 110 3 0.0272727272727273 0.136363636363636
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 0.00217881251239575 1001 142 19 0.133802816901408 0.018981018981019
GO:BP GO:0045937 positive regulation of phosphate metabolic process 0.00217881251239575 1001 142 19 0.133802816901408 0.018981018981019
GO:BP GO:0033630 positive regulation of cell adhesion mediated by integrin 0.00220034408797071 21 116 3 0.0258620689655172 0.142857142857143
GO:BP GO:0032963 collagen metabolic process 0.00232178584531112 114 95 5 0.0526315789473684 0.043859649122807
GO:BP GO:0051270 regulation of cellular component movement 0.00241549658771435 1141 97 16 0.164948453608247 0.014022787028922
GO:BP GO:0051716 cellular response to stimulus 0.00244741132776064 7781 131 76 0.580152671755725 0.00976738208456497
GO:BP GO:0032879 regulation of localization 0.00252742700951124 2872 97 29 0.298969072164948 0.0100974930362117
GO:BP GO:0040011 locomotion 0.00252742700951124 2028 128 28 0.21875 0.0138067061143984
GO:BP GO:0051702 biological process involved in interaction with symbiont 0.00259148169758145 96 116 5 0.0431034482758621 0.0520833333333333
GO:BP GO:0000165 MAPK cascade 0.00259148169758145 935 142 18 0.126760563380282 0.0192513368983957
GO:BP GO:0060401 cytosolic calcium ion transport 0.00267925691423401 186 93 6 0.0645161290322581 0.032258064516129
GO:BP GO:0000768 syncytium formation by plasma membrane fusion 0.00268900378004509 55 114 4 0.0350877192982456 0.0727272727272727
GO:BP GO:0140253 cell-cell fusion 0.00268900378004509 55 114 4 0.0350877192982456 0.0727272727272727
GO:BP GO:0051094 positive regulation of developmental process 0.0027422825314535 1341 3 3 1 0.00223713646532438
GO:BP GO:2000379 positive regulation of reactive oxygen species metabolic process 0.00279291238717332 107 106 5 0.0471698113207547 0.0467289719626168
GO:BP GO:0043547 positive regulation of GTPase activity 0.00281310136144103 413 142 11 0.0774647887323944 0.026634382566586
GO:BP GO:0030001 metal ion transport 0.00287761753600882 514 97 10 0.103092783505155 0.0194552529182879
GO:BP GO:0002347 response to tumor cell 0.00290519245804032 26 104 3 0.0288461538461538 0.115384615384615
GO:BP GO:0009074 aromatic amino acid family catabolic process 0.00293177518336586 20 137 3 0.0218978102189781 0.15
GO:BP GO:0060143 positive regulation of syncytium formation by plasma membrane fusion 0.0029672709710933 24 114 3 0.0263157894736842 0.125
GO:BP GO:1905517 macrophage migration 0.00301014630108296 56 116 4 0.0344827586206897 0.0714285714285714
GO:BP GO:0006949 syncytium formation 0.00301014630108296 57 114 4 0.0350877192982456 0.0701754385964912
GO:BP GO:0065008 regulation of biological quality 0.00302767849937355 4131 107 40 0.373831775700935 0.00968288549987896
GO:BP GO:0035821 modulation of process of other organism 0.00304480346995432 128 139 6 0.0431654676258993 0.046875
GO:BP GO:0002407 dendritic cell chemotaxis 0.00309105137715667 24 116 3 0.0258620689655172 0.125
GO:BP GO:0043933 protein-containing complex subunit organization 0.00309625908449046 1963 19 8 0.421052631578947 0.00407539480387163
GO:BP GO:1903428 positive regulation of reactive oxygen species biosynthetic process 0.00312152194608144 62 106 4 0.0377358490566038 0.0645161290322581
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.00315276756768622 1477 142 24 0.169014084507042 0.016249153689912
GO:BP GO:0030225 macrophage differentiation 0.00324078316028901 48 139 4 0.0287769784172662 0.0833333333333333
GO:BP GO:0006898 receptor-mediated endocytosis 0.0032573076251294 333 55 6 0.109090909090909 0.018018018018018
GO:BP GO:0009611 response to wounding 0.0032573076251294 674 90 11 0.122222222222222 0.0163204747774481
GO:BP GO:0016192 vesicle-mediated transport 0.00331856172876249 2180 116 27 0.232758620689655 0.0123853211009174
GO:BP GO:0006468 protein phosphorylation 0.00332151772651563 1668 142 26 0.183098591549296 0.0155875299760192
GO:BP GO:0031399 regulation of protein modification process 0.0034065191001273 1671 142 26 0.183098591549296 0.0155595451825254
GO:BP GO:0043067 regulation of programmed cell death 0.00352321565711683 1582 142 25 0.176056338028169 0.015802781289507
GO:BP GO:0032731 positive regulation of interleukin-1 beta production 0.00352863530233245 56 122 4 0.0327868852459016 0.0714285714285714
GO:BP GO:1905523 positive regulation of macrophage migration 0.00381212236868651 26 116 3 0.0258620689655172 0.115384615384615
GO:BP GO:0045637 regulation of myeloid cell differentiation 0.00394807349263428 263 72 6 0.0833333333333333 0.0228136882129278
GO:BP GO:0032651 regulation of interleukin-1 beta production 0.00400438065119139 102 122 5 0.040983606557377 0.0490196078431373
GO:BP GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 0.00400737457590085 133 142 6 0.0422535211267606 0.0451127819548872
GO:BP GO:0090025 regulation of monocyte chemotaxis 0.00422781075876764 27 116 3 0.0258620689655172 0.111111111111111
GO:BP GO:0045428 regulation of nitric oxide biosynthetic process 0.00425853502177923 68 106 4 0.0377358490566038 0.0588235294117647
GO:BP GO:0033674 positive regulation of kinase activity 0.0043829450578508 608 6 3 0.5 0.00493421052631579
GO:BP GO:2000146 negative regulation of cell motility 0.00446589710589413 369 95 8 0.0842105263157895 0.021680216802168
GO:BP GO:0001568 blood vessel development 0.00448466301189792 792 106 13 0.122641509433962 0.0164141414141414
GO:BP GO:0090087 regulation of peptide transport 0.00453682124030428 618 6 3 0.5 0.00485436893203883
GO:BP GO:0080164 regulation of nitric oxide metabolic process 0.00467164938235273 70 106 4 0.0377358490566038 0.0571428571428571
GO:BP GO:0045595 regulation of cell differentiation 0.00486534851596164 1679 3 3 1 0.00178677784395473
GO:BP GO:0051851 modulation by host of symbiont process 0.00488603320538117 65 116 4 0.0344827586206897 0.0615384615384615
GO:BP GO:0051402 neuron apoptotic process 0.00491199361690307 250 142 8 0.0563380281690141 0.032
GO:BP GO:0045766 positive regulation of angiogenesis 0.00492497888795839 187 106 6 0.0566037735849057 0.0320855614973262
GO:BP GO:1904018 positive regulation of vasculature development 0.00492497888795839 187 106 6 0.0566037735849057 0.0320855614973262
GO:BP GO:0000041 transition metal ion transport 0.00493441211766481 129 26 3 0.115384615384615 0.0232558139534884
GO:BP GO:0051271 negative regulation of cellular component movement 0.00496594976174346 377 95 8 0.0842105263157895 0.0212201591511936
GO:BP GO:0043687 post-translational protein modification 0.00496594976174346 362 99 8 0.0808080808080808 0.0220994475138122
GO:BP GO:0001894 tissue homeostasis 0.00496594976174346 270 74 6 0.0810810810810811 0.0222222222222222
GO:BP GO:0036336 dendritic cell migration 0.00496594976174346 29 116 3 0.0258620689655172 0.103448275862069
GO:BP GO:0051046 regulation of secretion 0.00499995319408631 647 6 3 0.5 0.00463678516228748
GO:BP GO:0042130 negative regulation of T cell proliferation 0.0050336731458235 70 48 3 0.0625 0.0428571428571429
GO:BP GO:0030888 regulation of B cell proliferation 0.00511069485244982 63 122 4 0.0327868852459016 0.0634920634920635
GO:BP GO:0032673 regulation of interleukin-4 production 0.00513356042148373 31 110 3 0.0272727272727273 0.0967741935483871
GO:BP GO:0071634 regulation of transforming growth factor beta production 0.00516456085883984 41 83 3 0.036144578313253 0.0731707317073171
GO:BP GO:0034764 positive regulation of transmembrane transport 0.00521413072632657 217 93 6 0.0645161290322581 0.0276497695852535
GO:BP GO:0034767 positive regulation of ion transmembrane transport 0.00521413072632657 217 93 6 0.0645161290322581 0.0276497695852535
GO:BP GO:0048514 blood vessel morphogenesis 0.00539937400569724 711 106 12 0.113207547169811 0.0168776371308017
GO:BP GO:0006958 complement activation, classical pathway 0.00557515698821161 142 96 5 0.0520833333333333 0.0352112676056338
GO:BP GO:0033273 response to vitamin 0.00557515698821161 98 139 5 0.0359712230215827 0.0510204081632653
GO:BP GO:0032633 interleukin-4 production 0.00557515698821161 32 110 3 0.0272727272727273 0.09375
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.00561178977669508 1645 142 25 0.176056338028169 0.0151975683890578
GO:BP GO:0019220 regulation of phosphate metabolic process 0.00561178977669508 1645 142 25 0.176056338028169 0.0151975683890578
GO:BP GO:0001525 angiogenesis 0.00565515021748253 617 106 11 0.10377358490566 0.0178282009724473
GO:BP GO:0071604 transforming growth factor beta production 0.0057276102586843 43 83 3 0.036144578313253 0.0697674418604651
GO:BP GO:0001818 negative regulation of cytokine production 0.0057276102586843 381 37 5 0.135135135135135 0.0131233595800525
GO:BP GO:0051347 positive regulation of transferase activity 0.0057276102586843 689 6 3 0.5 0.00435413642960813
GO:BP GO:0032965 regulation of collagen biosynthetic process 0.00595318521045178 47 77 3 0.038961038961039 0.0638297872340425
GO:BP GO:1904064 positive regulation of cation transmembrane transport 0.00598424783595184 150 93 5 0.0537634408602151 0.0333333333333333
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 0.00604833262961498 177 118 6 0.0508474576271186 0.0338983050847458
GO:BP GO:0051247 positive regulation of protein metabolic process 0.00610430996232658 1564 142 24 0.169014084507042 0.0153452685421995
GO:BP GO:0001944 vasculature development 0.00620881872535191 830 106 13 0.122641509433962 0.0156626506024096
GO:BP GO:0042554 superoxide anion generation 0.00620881872535191 35 106 3 0.0283018867924528 0.0857142857142857
GO:BP GO:0055094 response to lipoprotein particle 0.00620881872535191 35 106 3 0.0283018867924528 0.0857142857142857
GO:BP GO:0050766 positive regulation of phagocytosis 0.00620881872535191 67 55 3 0.0545454545454545 0.0447761194029851
GO:BP GO:0045824 negative regulation of innate immune response 0.00621618357726124 66 56 3 0.0535714285714286 0.0454545454545455
GO:BP GO:0051817 modulation of process of other organism involved in symbiotic interaction 0.00630713861748809 102 139 5 0.0359712230215827 0.0490196078431373
GO:BP GO:0006520 cellular amino acid metabolic process 0.00632835811528141 341 25 4 0.16 0.0117302052785924
GO:BP GO:0042551 neuron maturation 0.00634081682400036 45 83 3 0.036144578313253 0.0666666666666667
GO:BP GO:0001773 myeloid dendritic cell activation 0.00641533129667942 30 126 3 0.0238095238095238 0.1
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.0064875669137136 1042 107 15 0.14018691588785 0.0143953934740883
GO:BP GO:0033077 T cell differentiation in thymus 0.0064875669137136 76 110 4 0.0363636363636364 0.0526315789473684
GO:BP GO:0043524 negative regulation of neuron apoptotic process 0.00650031879257813 150 142 6 0.0422535211267606 0.04
GO:BP GO:0001959 regulation of cytokine-mediated signaling pathway 0.00653453283924211 184 116 6 0.0517241379310345 0.0326086956521739
GO:BP GO:0007267 cell-cell signaling 0.00656267268137315 1722 94 19 0.202127659574468 0.0110336817653891
GO:BP GO:0071402 cellular response to lipoprotein particle stimulus 0.00658010833251317 36 106 3 0.0283018867924528 0.0833333333333333
GO:BP GO:0040013 negative regulation of locomotion 0.0066017224599107 401 95 8 0.0842105263157895 0.0199501246882793
GO:BP GO:0048731 system development 0.00670529901218691 5052 131 53 0.404580152671756 0.0104908946951702
GO:BP GO:0032653 regulation of interleukin-10 production 0.00670934577244239 60 64 3 0.046875 0.05
GO:BP GO:0051345 positive regulation of hydrolase activity 0.00671800355853932 783 142 15 0.105633802816901 0.0191570881226054
GO:BP GO:1903169 regulation of calcium ion transmembrane transport 0.00710056178014325 158 93 5 0.0537634408602151 0.0316455696202532
GO:BP GO:0006809 nitric oxide biosynthetic process 0.00727301756323785 82 106 4 0.0377358490566038 0.0487804878048781
GO:BP GO:0032613 interleukin-10 production 0.00729474576902675 62 64 3 0.046875 0.0483870967741935
GO:BP GO:0010712 regulation of collagen metabolic process 0.00746359851883801 52 77 3 0.038961038961039 0.0576923076923077
GO:BP GO:0097242 amyloid-beta clearance 0.00750775682104111 38 106 3 0.0283018867924528 0.0789473684210526
GO:BP GO:0032501 multicellular organismal process 0.00770189217069886 7946 90 54 0.6 0.00679587213692424
GO:BP GO:1901215 negative regulation of neuron death 0.00770189217069886 213 142 7 0.0492957746478873 0.0328638497652582
GO:BP GO:1905954 positive regulation of lipid localization 0.00786802564305784 113 79 4 0.0506329113924051 0.0353982300884956
GO:BP GO:0032735 positive regulation of interleukin-12 production 0.00850078459821816 41 104 3 0.0288461538461538 0.0731707317073171
GO:BP GO:0060759 regulation of response to cytokine stimulus 0.00857236780391895 197 116 6 0.0517241379310345 0.0304568527918782
GO:BP GO:0046209 nitric oxide metabolic process 0.00860261057072034 87 106 4 0.0377358490566038 0.0459770114942529
GO:BP GO:0014065 phosphatidylinositol 3-kinase signaling 0.00860261057072034 161 142 6 0.0422535211267606 0.0372670807453416
GO:BP GO:0032964 collagen biosynthetic process 0.00878166517804691 56 77 3 0.038961038961039 0.0535714285714286
GO:BP GO:0051092 positive regulation of NF-kappaB transcription factor activity 0.0088362364682784 162 142 6 0.0422535211267606 0.037037037037037
GO:BP GO:0043087 regulation of GTPase activity 0.00884541770537408 493 142 11 0.0774647887323944 0.0223123732251521
GO:BP GO:2001057 reactive nitrogen species metabolic process 0.00888098370412907 88 106 4 0.0377358490566038 0.0454545454545455
GO:BP GO:0009072 aromatic amino acid family metabolic process 0.00894895409182868 32 137 3 0.0218978102189781 0.09375
GO:BP GO:0140546 defense response to symbiont 0.00899947161378106 267 87 6 0.0689655172413793 0.0224719101123595
GO:BP GO:0051607 defense response to virus 0.00899947161378106 267 87 6 0.0689655172413793 0.0224719101123595
GO:BP GO:0050727 regulation of inflammatory response 0.00903226669535432 381 83 7 0.0843373493975904 0.0183727034120735
GO:BP GO:1901655 cellular response to ketone 0.00907475305595883 97 97 4 0.0412371134020619 0.0412371134020619
GO:BP GO:0030101 natural killer cell activation 0.00907475305595883 84 112 4 0.0357142857142857 0.0476190476190476
GO:BP GO:0048585 negative regulation of response to stimulus 0.00938780942213299 1733 119 22 0.184873949579832 0.0126947489901904
GO:BP GO:0050864 regulation of B cell activation 0.00978160582243766 194 122 6 0.0491803278688525 0.0309278350515464
GO:BP GO:0009306 protein secretion 0.00981918683315021 384 26 4 0.153846153846154 0.0104166666666667
GO:BP GO:0035592 establishment of protein localization to extracellular region 0.00989827882187225 385 26 4 0.153846153846154 0.0103896103896104
GO:BP GO:0042981 regulation of apoptotic process 0.0101112531599903 1549 142 23 0.161971830985915 0.0148482892188509
GO:BP GO:0044070 regulation of anion transport 0.0102007666619782 896 6 3 0.5 0.00334821428571429
GO:BP GO:0006810 transport 0.0103371206409921 5224 124 51 0.411290322580645 0.00976263399693721
GO:BP GO:0071692 protein localization to extracellular region 0.0104328790319164 392 26 4 0.153846153846154 0.0102040816326531
GO:BP GO:0010942 positive regulation of cell death 0.010525631126856 684 122 12 0.0983606557377049 0.0175438596491228
GO:BP GO:0007520 myoblast fusion 0.0108725923940701 42 114 3 0.0263157894736842 0.0714285714285714
GO:BP GO:0043549 regulation of kinase activity 0.0108725923940701 921 6 3 0.5 0.00325732899022801
GO:BP GO:1905521 regulation of macrophage migration 0.0113139601388538 42 116 3 0.0258620689655172 0.0714285714285714
GO:BP GO:0035295 tube development 0.0116050840359457 1146 95 14 0.147368421052632 0.012216404886562
GO:BP GO:0030336 negative regulation of cell migration 0.011688257042723 353 95 7 0.0736842105263158 0.0198300283286119
GO:BP GO:1901216 positive regulation of neuron death 0.011958529371239 98 106 4 0.0377358490566038 0.0408163265306122
GO:BP GO:0050848 regulation of calcium-mediated signaling 0.0120022242482588 75 139 4 0.0287769784172662 0.0533333333333333
GO:BP GO:0044093 positive regulation of molecular function 0.0120873561302618 1771 142 25 0.176056338028169 0.0141163184641446
GO:BP GO:0050790 regulation of catalytic activity 0.012314557820693 2545 106 26 0.245283018867925 0.0102161100196464
GO:BP GO:0006928 movement of cell or subcellular component 0.0123587741254557 2311 128 28 0.21875 0.0121159671138035
GO:BP GO:0002218 activation of innate immune response 0.012977899398424 144 122 5 0.040983606557377 0.0347222222222222
GO:BP GO:0010468 regulation of gene expression 0.0130435596487677 5196 7 6 0.857142857142857 0.00115473441108545
GO:BP GO:0031640 killing of cells of other organism 0.0134612164289889 69 76 3 0.0394736842105263 0.0434782608695652
GO:BP GO:0033280 response to vitamin D 0.0135156957303045 38 139 3 0.0215827338129496 0.0789473684210526
GO:BP GO:0007160 cell-matrix adhesion 0.013685830170543 235 110 6 0.0545454545454545 0.025531914893617
GO:BP GO:0060337 type I interferon signaling pathway 0.0138001189449626 95 56 3 0.0535714285714286 0.0315789473684211
GO:BP GO:0051338 regulation of transferase activity 0.0140777110232921 1035 6 3 0.5 0.00289855072463768
GO:BP GO:0071357 cellular response to type I interferon 0.0140777110232921 96 56 3 0.0535714285714286 0.03125
GO:BP GO:0045860 positive regulation of protein kinase activity 0.0140777110232921 534 142 11 0.0774647887323944 0.0205992509363296
GO:BP GO:0010977 negative regulation of neuron projection development 0.0141088039220189 140 79 4 0.0506329113924051 0.0285714285714286
GO:BP GO:0043030 regulation of macrophage activation 0.0141088039220189 65 83 3 0.036144578313253 0.0461538461538462
GO:BP GO:0050764 regulation of phagocytosis 0.0141088039220189 98 55 3 0.0545454545454545 0.0306122448979592
GO:BP GO:1901698 response to nitrogen compound 0.0142756800355903 1172 106 15 0.141509433962264 0.0127986348122867
GO:BP GO:0031529 ruffle organization 0.0142817839607247 56 97 3 0.0309278350515464 0.0535714285714286
GO:BP GO:0050808 synapse organization 0.0146710093734274 428 83 7 0.0843373493975904 0.0163551401869159
GO:BP GO:0050691 regulation of defense response to virus by host 0.0148061808009408 43 129 3 0.0232558139534884 0.0697674418604651
GO:BP GO:0033628 regulation of cell adhesion mediated by integrin 0.0150023870732655 48 116 3 0.0258620689655172 0.0625
GO:BP GO:0048678 response to axon injury 0.0150574423489228 80 142 4 0.028169014084507 0.05
GO:BP GO:0002832 negative regulation of response to biotic stimulus 0.0152468683422539 100 56 3 0.0535714285714286 0.03
GO:BP GO:0034622 cellular protein-containing complex assembly 0.0154082079420005 1107 18 5 0.277777777777778 0.004516711833785
GO:BP GO:0034340 response to type I interferon 0.0156203178402117 101 56 3 0.0535714285714286 0.0297029702970297
GO:BP GO:0042493 response to drug 0.0159375205838238 396 15 3 0.2 0.00757575757575758
GO:BP GO:0002886 regulation of myeloid leukocyte mediated immunity 0.0159605044247865 54 106 3 0.0283018867924528 0.0555555555555556
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0161954082650692 2541 142 32 0.225352112676056 0.0125934671389217
GO:BP GO:1901564 organonitrogen compound metabolic process 0.0163099480939977 6792 49 28 0.571428571428571 0.00412249705535925
GO:BP GO:0010038 response to metal ion 0.0163099480939977 371 98 7 0.0714285714285714 0.0188679245283019
GO:BP GO:0051649 establishment of localization in cell 0.016434260702062 2813 124 31 0.25 0.0110202630643441
GO:BP GO:1903426 regulation of reactive oxygen species biosynthetic process 0.0165427168264154 111 106 4 0.0377358490566038 0.036036036036036
GO:BP GO:0051234 establishment of localization 0.0165547234289124 5372 124 51 0.411290322580645 0.00949367088607595
GO:BP GO:0050729 positive regulation of inflammatory response 0.0165547234289124 142 83 4 0.0481927710843374 0.028169014084507
GO:BP GO:0042180 cellular ketone metabolic process 0.0166405717828769 271 44 4 0.0909090909090909 0.014760147601476
GO:BP GO:0009636 response to toxic substance 0.0167563115681321 243 79 5 0.0632911392405063 0.0205761316872428
GO:BP GO:0006906 vesicle fusion 0.0170495256347153 108 55 3 0.0545454545454545 0.0277777777777778
GO:BP GO:0010243 response to organonitrogen compound 0.0170495256347153 1085 106 14 0.132075471698113 0.0129032258064516
GO:BP GO:0031214 biomineral tissue development 0.0170495256347153 164 73 4 0.0547945205479452 0.024390243902439
GO:BP GO:0042100 B cell proliferation 0.0170495256347153 98 122 4 0.0327868852459016 0.0408163265306122
GO:BP GO:0110148 biomineralization 0.0174790523632249 166 73 4 0.0547945205479452 0.0240963855421687
GO:BP GO:0045859 regulation of protein kinase activity 0.0174790523632249 809 142 14 0.0985915492957746 0.0173053152039555
GO:BP GO:0042113 B cell activation 0.0174790523632249 330 142 8 0.0563380281690141 0.0242424242424242
GO:BP GO:0006812 cation transport 0.0174790523632249 1197 97 14 0.144329896907216 0.0116959064327485
GO:BP GO:0022607 cellular component assembly 0.0175626630400551 3010 3 3 1 0.000996677740863787
GO:BP GO:0002820 negative regulation of adaptive immune response 0.0175626630400551 51 119 3 0.0252100840336134 0.0588235294117647
GO:BP GO:0048015 phosphatidylinositol-mediated signaling 0.0176452087188886 197 142 6 0.0422535211267606 0.0304568527918782
GO:BP GO:1901654 response to ketone 0.0182794402204943 204 97 5 0.0515463917525773 0.0245098039215686
GO:BP GO:0048871 multicellular organismal homeostasis 0.0183381153644186 530 90 8 0.0888888888888889 0.0150943396226415
GO:BP GO:0032655 regulation of interleukin-12 production 0.0184818969819063 60 104 3 0.0288461538461538 0.05
GO:BP GO:0032615 interleukin-12 production 0.0184818969819063 60 104 3 0.0288461538461538 0.05
GO:BP GO:0006811 ion transport 0.0185722517937448 3661 98 31 0.316326530612245 0.00846763179459164
GO:BP GO:0090174 organelle membrane fusion 0.0186292742878983 114 55 3 0.0545454545454545 0.0263157894736842
GO:BP GO:0030316 osteoclast differentiation 0.0186541398851578 98 64 3 0.046875 0.0306122448979592
GO:BP GO:0030168 platelet activation 0.0187150567605723 160 125 5 0.04 0.03125
GO:BP GO:0048017 inositol lipid-mediated signaling 0.0187873821821298 201 142 6 0.0422535211267606 0.0298507462686567
GO:BP GO:0002437 inflammatory response to antigenic stimulus 0.0188472644763089 65 97 3 0.0309278350515464 0.0461538461538462
GO:BP GO:0050798 activated T cell proliferation 0.0188472644763089 49 129 3 0.0232558139534884 0.0612244897959184
GO:BP GO:0051602 response to electrical stimulus 0.0192617665572607 45 142 3 0.0211267605633803 0.0666666666666667
GO:BP GO:0031663 lipopolysaccharide-mediated signaling pathway 0.0200675171022393 56 116 3 0.0258620689655172 0.0535714285714286
GO:BP GO:0010812 negative regulation of cell-substrate adhesion 0.0205401798087189 69 95 3 0.0315789473684211 0.0434782608695652
GO:BP GO:0045807 positive regulation of endocytosis 0.0205929796645738 101 128 4 0.03125 0.0396039603960396
GO:BP GO:0019752 carboxylic acid metabolic process 0.0207621497525923 1024 49 8 0.163265306122449 0.0078125
GO:BP GO:0044085 cellular component biogenesis 0.0207714185646038 3257 3 3 1 0.00092109303039607
GO:BP GO:0042060 wound healing 0.0211804555146132 549 90 8 0.0888888888888889 0.0145719489981785
GO:BP GO:0048872 homeostasis of number of cells 0.0213897554439136 261 26 3 0.115384615384615 0.0114942528735632
GO:BP GO:0070588 calcium ion transmembrane transport 0.0216027870956779 320 93 6 0.0645161290322581 0.01875
GO:BP GO:0032370 positive regulation of lipid transport 0.0227110147374693 87 79 3 0.0379746835443038 0.0344827586206897
GO:BP GO:0060249 anatomical structure homeostasis 0.0228985626112746 482 83 7 0.0843373493975904 0.0145228215767635
GO:BP GO:2000377 regulation of reactive oxygen species metabolic process 0.0235482837271112 203 106 5 0.0471698113207547 0.0246305418719212
GO:BP GO:0043436 oxoacid metabolic process 0.0237272885993911 1057 30 6 0.2 0.00567644276253548
GO:BP GO:0031589 cell-substrate adhesion 0.0241656593574666 367 110 7 0.0636363636363636 0.0190735694822888
GO:BP GO:0006801 superoxide metabolic process 0.02421333588877 67 106 3 0.0283018867924528 0.0447761194029851
GO:BP GO:0050817 coagulation 0.0242640780324228 354 87 6 0.0689655172413793 0.0169491525423729
GO:BP GO:0072593 reactive oxygen species metabolic process 0.024296355414898 290 106 6 0.0566037735849057 0.0206896551724138
GO:BP GO:0044106 cellular amine metabolic process 0.024462000319135 163 44 3 0.0681818181818182 0.0184049079754601
GO:BP GO:0002223 stimulatory C-type lectin receptor signaling pathway 0.0245426069870737 112 64 3 0.046875 0.0267857142857143
GO:BP GO:0051336 regulation of hydrolase activity 0.0247730434278871 1321 142 19 0.133802816901408 0.0143830431491294
GO:BP GO:0001952 regulation of cell-matrix adhesion 0.025177571634325 127 110 4 0.0363636363636364 0.031496062992126
GO:BP GO:0048469 cell maturation 0.0257959824492922 170 83 4 0.0481927710843374 0.0235294117647059
GO:BP GO:0010467 gene expression 0.0259022531191346 6179 7 6 0.857142857142857 0.000971030911150672
GO:BP GO:1903035 negative regulation of response to wounding 0.0259720492211274 93 79 3 0.0379746835443038 0.032258064516129
GO:BP GO:0002220 innate immune response activating cell surface receptor signaling pathway 0.0260172159886533 115 64 3 0.046875 0.0260869565217391
GO:BP GO:0009308 amine metabolic process 0.0260395813083769 168 44 3 0.0681818181818182 0.0178571428571429
GO:BP GO:0043112 receptor metabolic process 0.0261615161786049 174 128 5 0.0390625 0.028735632183908
GO:BP GO:0006082 organic acid metabolic process 0.0263475350257363 1090 30 6 0.2 0.0055045871559633
GO:BP GO:0045123 cellular extravasation 0.0264024232330197 70 106 3 0.0283018867924528 0.0428571428571429
GO:BP GO:0002758 innate immune response-activating signal transduction 0.0264024232330197 116 64 3 0.046875 0.0258620689655172
GO:BP GO:0046394 carboxylic acid biosynthetic process 0.0265806735143658 330 23 3 0.130434782608696 0.00909090909090909
GO:BP GO:0016310 phosphorylation 0.0266741308060741 2138 142 27 0.190140845070423 0.0126286248830683
GO:BP GO:1903409 reactive oxygen species biosynthetic process 0.0267016910652149 135 106 4 0.0377358490566038 0.0296296296296296
GO:BP GO:0048513 animal organ development 0.0271331124025164 3672 3 3 1 0.000816993464052288
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 0.0271750316730973 1202 114 15 0.131578947368421 0.0124792013311148
GO:BP GO:1902106 negative regulation of leukocyte differentiation 0.0274869070753166 105 72 3 0.0416666666666667 0.0285714285714286
GO:BP GO:0006909 phagocytosis 0.0275513407759436 387 108 7 0.0648148148148148 0.0180878552971576
GO:BP GO:0010035 response to inorganic substance 0.0278481576381656 575 26 4 0.153846153846154 0.00695652173913044
GO:BP GO:0016053 organic acid biosynthetic process 0.027907350786445 338 23 3 0.130434782608696 0.00887573964497041
GO:BP GO:1902531 regulation of intracellular signal transduction 0.0283003146553329 1842 142 24 0.169014084507042 0.0130293159609121
GO:BP GO:0032675 regulation of interleukin-6 production 0.0292329093775536 168 88 4 0.0454545454545455 0.0238095238095238
GO:BP GO:0043068 positive regulation of programmed cell death 0.0294547153213522 621 122 10 0.0819672131147541 0.0161030595813204
GO:BP GO:1903530 regulation of secretion by cell 0.0295970546008196 588 26 4 0.153846153846154 0.00680272108843537
GO:BP GO:0032755 positive regulation of interleukin-6 production 0.0295970546008196 89 88 3 0.0340909090909091 0.0337078651685393
GO:BP GO:0065009 regulation of molecular function 0.0296287361424698 3221 106 29 0.273584905660377 0.00900341508848184
GO:BP GO:0072359 circulatory system development 0.0296287361424698 1194 95 13 0.136842105263158 0.0108877721943049
GO:BP GO:1903707 negative regulation of hemopoiesis 0.0296287361424698 109 72 3 0.0416666666666667 0.0275229357798165
GO:BP GO:0031345 negative regulation of cell projection organization 0.0296677130398008 189 79 4 0.0506329113924051 0.0211640211640212
GO:BP GO:0035239 tube morphogenesis 0.0300517517517038 950 106 12 0.113207547169811 0.0126315789473684
GO:BP GO:0010518 positive regulation of phospholipase activity 0.0302335485197717 62 128 3 0.0234375 0.0483870967741935
GO:BP GO:0048856 anatomical structure development 0.0302853311379414 6106 135 59 0.437037037037037 0.00966262692433672
GO:BP GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 0.0305793913645813 148 102 4 0.0392156862745098 0.027027027027027
GO:BP GO:0032635 interleukin-6 production 0.0307525237407348 172 88 4 0.0454545454545455 0.0232558139534884
GO:BP GO:0051246 regulation of protein metabolic process 0.0309217876387586 2704 142 32 0.225352112676056 0.0118343195266272
GO:BP GO:0019538 protein metabolic process 0.0309525177696038 5808 128 54 0.421875 0.00929752066115703
GO:BP GO:1903034 regulation of response to wounding 0.0310476278848148 169 90 4 0.0444444444444444 0.0236686390532544
GO:BP GO:0022604 regulation of cell morphogenesis 0.0310714822658385 309 107 6 0.0560747663551402 0.0194174757281553
GO:BP GO:0007275 multicellular organism development 0.0310714822658385 5613 135 55 0.407407407407407 0.00979868163192589
GO:BP GO:0032502 developmental process 0.0313133230126985 6628 92 45 0.489130434782609 0.0067893783946892
GO:BP GO:0048284 organelle fusion 0.0316401044401675 148 55 3 0.0545454545454545 0.0202702702702703
GO:BP GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 0.0319406848428197 234 102 5 0.0490196078431373 0.0213675213675214
GO:BP GO:1904062 regulation of cation transmembrane transport 0.0322826259290326 360 93 6 0.0645161290322581 0.0166666666666667
GO:BP GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 0.0335807881705381 71 118 3 0.0254237288135593 0.0422535211267606
GO:BP GO:0060255 regulation of macromolecule metabolic process 0.0338351595919123 6603 7 6 0.857142857142857 0.000908677873693776
GO:BP GO:0010810 regulation of cell-substrate adhesion 0.0341585555015641 222 110 5 0.0454545454545455 0.0225225225225225
GO:BP GO:0032663 regulation of interleukin-2 production 0.0342647532607535 61 139 3 0.0215827338129496 0.0491803278688525
GO:BP GO:1905952 regulation of lipid localization 0.0343015794510841 201 79 4 0.0506329113924051 0.0199004975124378
GO:BP GO:0044281 small molecule metabolic process 0.0355214867597382 1921 49 11 0.224489795918367 0.00572618427902134
GO:BP GO:0051668 localization within membrane 0.0355214867597382 77 112 3 0.0267857142857143 0.038961038961039
GO:BP GO:0061025 membrane fusion 0.0357438224401002 179 90 4 0.0444444444444444 0.0223463687150838
GO:BP GO:1901605 alpha-amino acid metabolic process 0.035856156388336 198 44 3 0.0681818181818182 0.0151515151515152
GO:BP GO:0032623 interleukin-2 production 0.0364659715033041 63 139 3 0.0215827338129496 0.0476190476190476
GO:BP GO:0007186 G protein-coupled receptor signaling pathway 0.0364659715033041 1355 116 16 0.137931034482759 0.0118081180811808
GO:BP GO:0008360 regulation of cell shape 0.0378248465608802 154 107 4 0.0373831775700935 0.025974025974026
GO:BP GO:0030154 cell differentiation 0.0390159905164874 4350 131 43 0.32824427480916 0.00988505747126437
GO:BP GO:0001666 response to hypoxia 0.0398127708197272 367 97 6 0.0618556701030928 0.0163487738419619
GO:BP GO:0050688 regulation of defense response to virus 0.0401287499681546 71 129 3 0.0232558139534884 0.0422535211267606
GO:BP GO:0014070 response to organic cyclic compound 0.0402394721584822 967 97 11 0.11340206185567 0.0113753877973113
GO:BP GO:0048869 cellular developmental process 0.0410192251228977 4428 3 3 1 0.000677506775067751
GO:BP GO:0010517 regulation of phospholipase activity 0.0417192870976664 73 128 3 0.0234375 0.0410958904109589
GO:BP GO:0006897 endocytosis 0.0417192870976664 696 14 3 0.214285714285714 0.00431034482758621
GO:BP GO:0044706 multi-multicellular organism process 0.042374071649547 227 76 4 0.0526315789473684 0.0176211453744493
GO:BP GO:0001960 negative regulation of cytokine-mediated signaling pathway 0.0433625927080947 82 116 3 0.0258620689655172 0.0365853658536585
GO:BP GO:0038034 signal transduction in absence of ligand 0.0440005992423585 71 135 3 0.0222222222222222 0.0422535211267606
GO:BP GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 0.0440005992423585 71 135 3 0.0222222222222222 0.0422535211267606
GO:BP GO:0060193 positive regulation of lipase activity 0.0441763119703841 75 128 3 0.0234375 0.04
GO:BP GO:0043069 negative regulation of programmed cell death 0.0443876771093164 943 142 14 0.0985915492957746 0.0148462354188759
GO:BP GO:0060548 negative regulation of cell death 0.0444157508121481 1038 142 15 0.105633802816901 0.0144508670520231
GO:BP GO:0008285 negative regulation of cell population proliferation 0.0447121169837023 790 23 4 0.173913043478261 0.00506329113924051
GO:BP GO:0006464 cellular protein modification process 0.0447565978264911 4041 142 43 0.302816901408451 0.0106409304627567
GO:BP GO:0036211 protein modification process 0.0447565978264911 4041 142 43 0.302816901408451 0.0106409304627567
GO:BP GO:0036293 response to decreased oxygen levels 0.0454131436505685 382 97 6 0.0618556701030928 0.0157068062827225
GO:BP GO:0032760 positive regulation of tumor necrosis factor production 0.0462921497172284 88 112 3 0.0267857142857143 0.0340909090909091
GO:BP GO:0051641 cellular localization 0.0464685492260928 3541 114 32 0.280701754385965 0.0090369951990963
GO:BP GO:0019222 regulation of metabolic process 0.0464974488169768 7148 7 6 0.857142857142857 0.000839395635142697
GO:BP GO:0032680 regulation of tumor necrosis factor production 0.0485602217443671 163 112 4 0.0357142857142857 0.0245398773006135
GO:BP GO:0042063 gliogenesis 0.0489209152473793 308 90 5 0.0555555555555556 0.0162337662337662
GO:BP GO:0022617 extracellular matrix disassembly 0.0489682382675722 82 124 3 0.0241935483870968 0.0365853658536585
GO:BP GO:0015031 protein transport 0.0491254640931864 1929 6 3 0.5 0.0015552099533437
GO:BP GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 0.0491866287475781 91 112 3 0.0267857142857143 0.032967032967033
GO:BP GO:0060761 negative regulation of response to cytokine stimulus 0.0493040427867226 88 116 3 0.0258620689655172 0.0340909090909091
GO:BP GO:0043413 macromolecule glycosylation 0.0494558073556078 251 41 3 0.0731707317073171 0.0119521912350598
GO:BP GO:0006486 protein glycosylation 0.0494558073556078 251 41 3 0.0731707317073171 0.0119521912350598
GO:BP GO:0032640 tumor necrosis factor production 0.0496150950812067 165 112 4 0.0357142857142857 0.0242424242424242
GO:BP GO:0042509 regulation of tyrosine phosphorylation of STAT protein 0.0496150950812067 87 118 3 0.0254237288135593 0.0344827586206897
GO:CC GO:0042611 MHC protein complex 2.10348335525252e-25 24 22 11 0.5 0.458333333333333
GO:CC GO:0042613 MHC class II protein complex 2.563775530347e-23 16 16 9 0.5625 0.5625
GO:CC GO:0098553 lumenal side of endoplasmic reticulum membrane 7.07073827048512e-17 25 22 8 0.363636363636364 0.32
GO:CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 7.07073827048512e-17 25 22 8 0.363636363636364 0.32
GO:CC GO:0009986 cell surface 5.2541778549219e-16 899 142 37 0.26056338028169 0.0411568409343715
GO:CC GO:0098576 lumenal side of membrane 6.01938877665929e-16 33 22 8 0.363636363636364 0.242424242424242
GO:CC GO:0098552 side of membrane 5.69515958863499e-15 619 139 30 0.215827338129496 0.0484652665589661
GO:CC GO:0012507 ER to Golgi transport vesicle membrane 5.28878859580245e-14 57 22 8 0.363636363636364 0.140350877192982
GO:CC GO:0030669 clathrin-coated endocytic vesicle membrane 9.32775874601747e-14 36 9 6 0.666666666666667 0.166666666666667
GO:CC GO:0009897 external side of plasma membrane 9.32775874601747e-14 408 139 24 0.172661870503597 0.0588235294117647
GO:CC GO:0030666 endocytic vesicle membrane 1.90199026492039e-13 159 26 10 0.384615384615385 0.0628930817610063
GO:CC GO:0045334 clathrin-coated endocytic vesicle 9.5283082264966e-13 54 9 6 0.666666666666667 0.111111111111111
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 1.49394813738962e-12 90 22 8 0.363636363636364 0.0888888888888889
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 1.70589071998412e-12 158 22 9 0.409090909090909 0.0569620253164557
GO:CC GO:0030139 endocytic vesicle 2.29775980728116e-12 306 26 11 0.423076923076923 0.0359477124183007
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 2.34315739587812e-12 166 22 9 0.409090909090909 0.0542168674698795
GO:CC GO:0005615 extracellular space 1.04314396502092e-11 3594 97 50 0.515463917525773 0.0139120756816917
GO:CC GO:0005576 extracellular region 1.07668171577372e-11 4567 137 72 0.525547445255474 0.0157652726078388
GO:CC GO:0098852 lytic vacuole membrane 1.82462429236235e-11 383 10 8 0.8 0.02088772845953
GO:CC GO:0005765 lysosomal membrane 1.82462429236235e-11 383 10 8 0.8 0.02088772845953
GO:CC GO:0032588 trans-Golgi network membrane 1.82462429236235e-11 94 9 6 0.666666666666667 0.0638297872340425
GO:CC GO:0031982 vesicle 1.83728978385491e-11 4055 109 57 0.522935779816514 0.0140567200986437
GO:CC GO:0005774 vacuolar membrane 4.95358312177244e-11 441 10 8 0.8 0.018140589569161
GO:CC GO:0030665 clathrin-coated vesicle membrane 4.95358312177244e-11 114 9 6 0.666666666666667 0.0526315789473684
GO:CC GO:0030662 coated vesicle membrane 1.9256719357701e-10 177 22 8 0.363636363636364 0.0451977401129944
GO:CC GO:0000323 lytic vacuole 2.22933725824497e-10 712 30 13 0.433333333333333 0.0182584269662921
GO:CC GO:0005764 lysosome 2.22933725824497e-10 712 30 13 0.433333333333333 0.0182584269662921
GO:CC GO:0010008 endosome membrane 2.82498349466476e-10 505 26 11 0.423076923076923 0.0217821782178218
GO:CC GO:0098797 plasma membrane protein complex 3.13485936784252e-10 694 16 10 0.625 0.0144092219020173
GO:CC GO:0030658 transport vesicle membrane 6.08684162557725e-10 209 22 8 0.363636363636364 0.0382775119617225
GO:CC GO:0031410 cytoplasmic vesicle 8.52158833041092e-10 2424 142 48 0.338028169014085 0.0198019801980198
GO:CC GO:0097708 intracellular vesicle 8.73588541733707e-10 2428 142 48 0.338028169014085 0.0197693574958814
GO:CC GO:0030136 clathrin-coated vesicle 8.73588541733707e-10 193 9 6 0.666666666666667 0.0310880829015544
GO:CC GO:0005773 vacuole 8.81547591282721e-10 810 30 13 0.433333333333333 0.0160493827160494
GO:CC GO:0098796 membrane protein complex 1.23697095238213e-09 1322 29 15 0.517241379310345 0.0113464447806354
GO:CC GO:0031301 integral component of organelle membrane 1.86740115543863e-09 382 22 9 0.409090909090909 0.0235602094240838
GO:CC GO:0031300 intrinsic component of organelle membrane 3.62052113570105e-09 413 22 9 0.409090909090909 0.0217917675544794
GO:CC GO:0005802 trans-Golgi network 3.62052113570105e-09 250 9 6 0.666666666666667 0.024
GO:CC GO:0030135 coated vesicle 5.63714090736526e-09 295 14 7 0.5 0.023728813559322
GO:CC GO:0005768 endosome 7.18580476992134e-09 987 16 10 0.625 0.0101317122593718
GO:CC GO:0005783 endoplasmic reticulum 2.68505807446756e-08 1982 40 19 0.475 0.00958627648839556
GO:CC GO:0030133 transport vesicle 5.51027018954517e-08 414 14 7 0.5 0.0169082125603865
GO:CC GO:0042824 MHC class I peptide loading complex 6.28159002991158e-08 9 55 4 0.0727272727272727 0.444444444444444
GO:CC GO:0012505 endomembrane system 6.97833299509246e-08 4640 42 28 0.666666666666667 0.00603448275862069
GO:CC GO:0070062 extracellular exosome 1.63803071908011e-07 2176 108 34 0.314814814814815 0.015625
GO:CC GO:0005789 endoplasmic reticulum membrane 2.22872238816766e-07 1117 40 14 0.35 0.0125335720680394
GO:CC GO:0098588 bounding membrane of organelle 2.22872238816766e-07 2158 27 15 0.555555555555556 0.00695088044485635
GO:CC GO:0098827 endoplasmic reticulum subcompartment 2.30836969429296e-07 1122 40 14 0.35 0.0124777183600713
GO:CC GO:0071944 cell periphery 2.36128847580654e-07 6169 115 66 0.573913043478261 0.0106986545631383
GO:CC GO:0045335 phagocytic vesicle 2.53446731416311e-07 137 98 9 0.0918367346938776 0.0656934306569343
GO:CC GO:0030659 cytoplasmic vesicle membrane 2.53446731416311e-07 779 26 10 0.384615384615385 0.0128369704749679
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 2.57375117640264e-07 1139 40 14 0.35 0.0122914837576822
GO:CC GO:0012506 vesicle membrane 3.13424735309391e-07 800 26 10 0.384615384615385 0.0125
GO:CC GO:0000139 Golgi membrane 3.32324379775074e-07 771 27 10 0.37037037037037 0.012970168612192
GO:CC GO:0043230 extracellular organelle 3.42530042683662e-07 2263 108 34 0.314814814814815 0.0150243040212108
GO:CC GO:1903561 extracellular vesicle 3.42530042683662e-07 2261 108 34 0.314814814814815 0.0150375939849624
GO:CC GO:0005788 endoplasmic reticulum lumen 3.42530042683662e-07 307 79 11 0.139240506329114 0.0358306188925081
GO:CC GO:0005770 late endosome 3.68535859084938e-07 275 16 6 0.375 0.0218181818181818
GO:CC GO:0031902 late endosome membrane 4.79749550440834e-07 140 16 5 0.3125 0.0357142857142857
GO:CC GO:0030670 phagocytic vesicle membrane 4.79749550440834e-07 76 55 6 0.109090909090909 0.0789473684210526
GO:CC GO:0034364 high-density lipoprotein particle 6.80028393370605e-07 29 79 5 0.0632911392405063 0.172413793103448
GO:CC GO:0005886 plasma membrane 1.03514329217091e-06 5681 115 61 0.530434782608696 0.0107375462066538
GO:CC GO:0098791 Golgi apparatus subcompartment 1.03514329217091e-06 885 27 10 0.37037037037037 0.0112994350282486
GO:CC GO:0001772 immunological synapse 1.12457717124173e-06 43 114 6 0.0526315789473684 0.13953488372093
GO:CC GO:0031984 organelle subcompartment 1.7931843719527e-06 1773 41 16 0.390243902439024 0.00902425267907501
GO:CC GO:1990777 lipoprotein particle 2.5413498121483e-06 38 79 5 0.0632911392405063 0.131578947368421
GO:CC GO:0034358 plasma lipoprotein particle 2.5413498121483e-06 38 79 5 0.0632911392405063 0.131578947368421
GO:CC GO:0032994 protein-lipid complex 3.70212318266522e-06 41 79 5 0.0632911392405063 0.121951219512195
GO:CC GO:0071682 endocytic vesicle lumen 6.37186428770711e-06 20 79 4 0.0506329113924051 0.2
GO:CC GO:0031224 intrinsic component of membrane 7.66190335055726e-06 5868 142 71 0.5 0.0120995228357192
GO:CC GO:0072562 blood microparticle 9.22768188751062e-06 140 79 7 0.0886075949367089 0.05
GO:CC GO:0031090 organelle membrane 1.73162689035708e-05 3612 41 21 0.51219512195122 0.00581395348837209
GO:CC GO:0032991 protein-containing complex 1.79114227008471e-05 5548 20 16 0.8 0.00288392213410238
GO:CC GO:0016021 integral component of membrane 6.14192670413628e-05 5711 142 67 0.471830985915493 0.0117317457538084
GO:CC GO:0005794 Golgi apparatus 0.000119036438104692 1623 9 6 0.666666666666667 0.00369685767097967
GO:CC GO:0140534 endoplasmic reticulum protein-containing complex 0.000154873316264955 128 55 5 0.0909090909090909 0.0390625
GO:CC GO:0070820 tertiary granule 0.000254640294279919 163 114 7 0.0614035087719298 0.0429447852760736
GO:CC GO:0031226 intrinsic component of plasma membrane 0.000308338197443997 1726 142 28 0.197183098591549 0.0162224797219003
GO:CC GO:0005887 integral component of plasma membrane 0.000344992268176705 1645 142 27 0.190140845070423 0.0164133738601824
GO:CC GO:0030141 secretory granule 0.000470265053821924 851 122 16 0.131147540983607 0.0188014101057579
GO:CC GO:0043227 membrane-bounded organelle 0.00130128660441223 12858 44 40 0.909090909090909 0.00311090371752994
GO:CC GO:0035580 specific granule lumen 0.00133846985499433 61 42 3 0.0714285714285714 0.0491803278688525
GO:CC GO:0016020 membrane 0.00148044511484256 9838 142 94 0.661971830985915 0.00955478755844684
GO:CC GO:0042581 specific granule 0.00152187142218278 158 114 6 0.0526315789473684 0.0379746835443038
GO:CC GO:0099503 secretory vesicle 0.00155894089195422 1020 137 18 0.131386861313869 0.0176470588235294
GO:CC GO:0034774 secretory granule lumen 0.0025999572692672 320 42 5 0.119047619047619 0.015625
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.00268927693002828 324 42 5 0.119047619047619 0.0154320987654321
GO:CC GO:0031983 vesicle lumen 0.00273478561089804 326 42 5 0.119047619047619 0.0153374233128834
GO:CC GO:0070821 tertiary granule membrane 0.00342357483738493 72 114 4 0.0350877192982456 0.0555555555555556
GO:CC GO:0005737 cytoplasm 0.00362441193115018 11911 42 36 0.857142857142857 0.00302241625388297
GO:CC GO:0043226 organelle 0.0042166371361911 14008 44 41 0.931818181818182 0.00292689891490577
GO:CC GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 0.0046109626428259 74 55 3 0.0545454545454545 0.0405405405405405
GO:CC GO:0031225 anchored component of membrane 0.0139034650599849 174 115 5 0.0434782608695652 0.028735632183908
GO:CC GO:0101003 ficolin-1-rich granule membrane 0.0150240399572785 60 106 3 0.0283018867924528 0.05
GO:CC GO:0005581 collagen trimer 0.0176018511916228 95 72 3 0.0416666666666667 0.0315789473684211
GO:CC GO:0043235 receptor complex 0.0182864652010736 522 142 10 0.0704225352112676 0.0191570881226054
GO:CC GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 0.0191410784709846 131 55 3 0.0545454545454545 0.0229007633587786
GO:CC GO:0098802 plasma membrane signaling receptor complex 0.0192640124231439 300 139 7 0.0503597122302158 0.0233333333333333
GO:CC GO:0101002 ficolin-1-rich granule 0.0193161741426419 184 122 5 0.040983606557377 0.0271739130434783
GO:CC GO:0031012 extracellular matrix 0.0226826465488638 562 97 8 0.0824742268041237 0.0142348754448399
GO:CC GO:0030312 external encapsulating structure 0.0227298077160182 563 97 8 0.0824742268041237 0.0142095914742451
GO:CC GO:0070161 anchoring junction 0.0248211106807401 836 125 12 0.096 0.0143540669856459
GO:CC GO:0005791 rough endoplasmic reticulum 0.0266547896337845 86 98 3 0.0306122448979592 0.0348837209302326
GO:CC GO:0030667 secretory granule membrane 0.0266547896337845 303 114 6 0.0526315789473684 0.0198019801980198
GO:CC GO:0001669 acrosomal vesicle 0.0282478616785705 119 137 4 0.0291970802919708 0.0336134453781513
GO:CC GO:0035579 specific granule membrane 0.0393610392381911 90 114 3 0.0263157894736842 0.0333333333333333
GO:CC GO:0043025 neuronal cell body 0.0410532187351578 518 98 7 0.0714285714285714 0.0135135135135135
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.0417005293874048 11296 42 32 0.761904761904762 0.0028328611898017
GO:CC GO:0005925 focal adhesion 0.0455910395563599 420 124 7 0.0564516129032258 0.0166666666666667
GO:CC GO:0035578 azurophil granule lumen 0.0458459410829006 91 122 3 0.0245901639344262 0.032967032967033
GO:CC GO:0062023 collagen-containing extracellular matrix 0.0458459410829006 421 97 6 0.0618556701030928 0.0142517814726841
GO:CC GO:0044297 cell body 0.0471893314917343 592 110 8 0.0727272727272727 0.0135135135135135
GO:CC GO:0030055 cell-substrate junction 0.0472543262270394 427 124 7 0.0564516129032258 0.0163934426229508
GO:MF GO:0042605 peptide antigen binding 4.74568652958668e-13 30 39 8 0.205128205128205 0.266666666666667
GO:MF GO:0023026 MHC class II protein complex binding 3.54273156021256e-10 17 16 5 0.3125 0.294117647058824
GO:MF GO:0023023 MHC protein complex binding 2.01989816800863e-09 25 16 5 0.3125 0.2
GO:MF GO:0032395 MHC class II receptor activity 2.5737761192768e-08 8 4 3 0.75 0.375
GO:MF GO:0042277 peptide binding 4.20774701137903e-08 314 62 12 0.193548387096774 0.0382165605095541
GO:MF GO:0003823 antigen binding 4.30632952139756e-08 163 22 7 0.318181818181818 0.0429447852760736
GO:MF GO:0008009 chemokine activity 4.51092431556798e-08 49 116 8 0.0689655172413793 0.163265306122449
GO:MF GO:0005102 signaling receptor binding 1.12389312809985e-07 1672 142 37 0.26056338028169 0.0221291866028708
GO:MF GO:0140375 immune receptor activity 1.36302031535193e-07 133 4 4 1 0.0300751879699248
GO:MF GO:0048248 CXCR3 chemokine receptor binding 1.43208924975929e-07 5 93 4 0.043010752688172 0.8
GO:MF GO:0033218 amide binding 2.15913290598033e-07 389 62 12 0.193548387096774 0.0308483290488432
GO:MF GO:0042379 chemokine receptor binding 6.20346655390947e-07 72 116 8 0.0689655172413793 0.111111111111111
GO:MF GO:0045236 CXCR chemokine receptor binding 8.58193046285418e-07 18 93 5 0.0537634408602151 0.277777777777778
GO:MF GO:0046978 TAP1 binding 5.97565412807712e-06 6 39 3 0.0769230769230769 0.5
GO:MF GO:0044877 protein-containing complex binding 7.70088916582329e-06 1287 139 28 0.201438848920863 0.0217560217560218
GO:MF GO:0046977 TAP binding 2.0579224792921e-05 9 39 3 0.0769230769230769 0.333333333333333
GO:MF GO:0005126 cytokine receptor binding 3.4185759217487e-05 275 142 12 0.0845070422535211 0.0436363636363636
GO:MF GO:0031726 CCR1 chemokine receptor binding 0.00010946237639074 6 116 3 0.0258620689655172 0.5
GO:MF GO:0042056 chemoattractant activity 0.000115937034674178 37 128 5 0.0390625 0.135135135135135
GO:MF GO:0005178 integrin binding 0.00019354083828298 147 131 8 0.0610687022900763 0.054421768707483
GO:MF GO:0048020 CCR chemokine receptor binding 0.000234075811371381 48 116 5 0.0431034482758621 0.104166666666667
GO:MF GO:0031730 CCR5 chemokine receptor binding 0.000245313411582024 8 116 3 0.0258620689655172 0.375
GO:MF GO:0001664 G protein-coupled receptor binding 0.000262165822977743 292 116 10 0.0862068965517241 0.0342465753424658
GO:MF GO:0005125 cytokine activity 0.000286704157245365 235 116 9 0.0775862068965517 0.0382978723404255
GO:MF GO:0004888 transmembrane signaling receptor activity 0.000365172291278642 1269 4 4 1 0.00315208825847124
GO:MF GO:0038023 signaling receptor activity 0.000595640704213602 1458 4 4 1 0.00274348422496571
GO:MF GO:0060089 molecular transducer activity 0.000595640704213602 1458 4 4 1 0.00274348422496571
GO:MF GO:0042287 MHC protein binding 0.00107198047509959 39 39 3 0.0769230769230769 0.0769230769230769
GO:MF GO:0008201 heparin binding 0.00268252607630297 168 93 6 0.0645161290322581 0.0357142857142857
GO:MF GO:0001848 complement binding 0.00288119855028467 21 106 3 0.0283018867924528 0.142857142857143
GO:MF GO:0042802 identical protein binding 0.00457395182285344 2067 142 30 0.211267605633803 0.0145137880986938
GO:MF GO:0048018 receptor ligand activity 0.0072095860544091 494 128 11 0.0859375 0.0222672064777328
GO:MF GO:0042803 protein homodimerization activity 0.0072095860544091 676 142 14 0.0985915492957746 0.0207100591715976
GO:MF GO:0019865 immunoglobulin binding 0.0072095860544091 23 139 3 0.0215827338129496 0.130434782608696
GO:MF GO:0030546 signaling receptor activator activity 0.00727774771519395 501 128 11 0.0859375 0.0219560878243513
GO:MF GO:0005539 glycosaminoglycan binding 0.0121482250526138 238 93 6 0.0645161290322581 0.0252100840336134
GO:MF GO:0001540 amyloid-beta binding 0.0124949361005325 83 106 4 0.0377358490566038 0.0481927710843374
GO:MF GO:0030545 receptor regulator activity 0.012730106784714 545 128 11 0.0859375 0.0201834862385321
GO:MF GO:0042626 ATPase-coupled transmembrane transporter activity 0.0154369213016601 67 67 3 0.0447761194029851 0.0447761194029851
GO:MF GO:1901681 sulfur compound binding 0.0168069766959874 264 93 6 0.0645161290322581 0.0227272727272727
GO:MF GO:0015399 primary active transmembrane transporter activity 0.0176870820123141 74 67 3 0.0447761194029851 0.0405405405405405
GO:MF GO:0001618 virus receptor activity 0.0176870820123141 76 139 4 0.0287769784172662 0.0526315789473684
GO:MF GO:0140272 exogenous protein binding 0.0181039873706655 77 139 4 0.0287769784172662 0.051948051948052
GO:MF GO:0019955 cytokine binding 0.0230692874099434 138 139 5 0.0359712230215827 0.036231884057971
GO:MF GO:0051082 unfolded protein binding 0.0252006707685091 112 55 3 0.0545454545454545 0.0267857142857143
GO:MF GO:0004896 cytokine receptor activity 0.0333201041168492 99 139 4 0.0287769784172662 0.0404040404040404
GO:MF GO:0046983 protein dimerization activity 0.0357106817470382 1069 142 16 0.112676056338028 0.0149672591206735
GO:MF GO:0008509 anion transmembrane transporter activity 0.04490600380474 464 74 6 0.0810810810810811 0.0129310344827586
GO:MF GO:0022853 active ion transmembrane transporter activity 0.04490600380474 213 74 4 0.0540540540540541 0.0187793427230047
HP HP:0004431 Complement deficiency 0.00036520071497061 28 73 7 0.0958904109589041 0.25
HP HP:0005339 Abnormality of complement system 0.000390058834701902 31 73 7 0.0958904109589041 0.225806451612903
HP HP:0000793 Membranoproliferative glomerulonephritis 0.00092603943237338 7 72 4 0.0555555555555556 0.571428571428571
HP HP:0005356 Decreased serum complement factor I 0.00092603943237338 7 72 4 0.0555555555555556 0.571428571428571
HP HP:0001701 Pericarditis 0.00490968399252594 34 7 3 0.428571428571429 0.0882352941176471
HP HP:0100749 Chest pain 0.00632541668850291 93 10 4 0.4 0.043010752688172
HP HP:0045073 Serositis 0.00632541668850291 40 7 3 0.428571428571429 0.075
HP HP:0032436 Abnormal C-reactive protein level 0.00632541668850291 52 7 3 0.428571428571429 0.0576923076923077
HP HP:0002113 Pulmonary infiltrates 0.00632541668850291 53 7 3 0.428571428571429 0.0566037735849057
HP HP:0025021 Abnormal erythrocyte sedimentation rate 0.00632541668850291 49 7 3 0.428571428571429 0.0612244897959184
HP HP:0001937 Microangiopathic hemolytic anemia 0.00632541668850291 12 73 4 0.0547945205479452 0.333333333333333
HP HP:0011227 Elevated C-reactive protein level 0.00632541668850291 51 7 3 0.428571428571429 0.0588235294117647
HP HP:0003565 Elevated erythrocyte sedimentation rate 0.00632541668850291 48 7 3 0.428571428571429 0.0625
HP HP:0001287 Meningitis 0.00681622337096464 72 28 5 0.178571428571429 0.0694444444444444
HP HP:0000873 Diabetes insipidus 0.00681622337096464 57 7 3 0.428571428571429 0.0526315789473684
HP HP:0002105 Hemoptysis 0.00690202931046158 59 7 3 0.428571428571429 0.0508474576271186
HP HP:0002960 Autoimmunity 0.00691742332254279 170 73 11 0.150684931506849 0.0647058823529412
HP HP:0033331 Acute phase response 0.00797682120627816 65 7 3 0.428571428571429 0.0461538461538462
HP HP:0012735 Cough 0.00839729514880165 128 10 4 0.4 0.03125
HP HP:0001697 Abnormal pericardium morphology 0.00839729514880165 68 7 3 0.428571428571429 0.0441176470588235
HP HP:0002206 Pulmonary fibrosis 0.00839729514880165 69 7 3 0.428571428571429 0.0434782608695652
HP HP:0031983 Abnormal pulmonary thoracic imaging finding 0.00879614738751282 71 7 3 0.428571428571429 0.0422535211267606
HP HP:0002725 Systemic lupus erythematosus 0.00946129749006776 32 73 5 0.0684931506849315 0.15625
HP HP:0011450 Unusual CNS infection 0.0108485310923995 87 28 5 0.178571428571429 0.0574712643678161
HP HP:0002091 Restrictive ventilatory defect 0.0112676659118364 80 7 3 0.428571428571429 0.0375
HP HP:0004936 Venous thrombosis 0.0117246736667343 82 7 3 0.428571428571429 0.0365853658536585
HP HP:0002103 Abnormal pleura morphology 0.0118104688180985 84 7 3 0.428571428571429 0.0357142857142857
HP HP:0032158 Unusual infection by anatomical site 0.0118104688180985 91 28 5 0.178571428571429 0.0549450549450549
HP HP:0011037 Decreased urine output 0.0137284223230954 21 69 4 0.0579710144927536 0.19047619047619
HP HP:0002027 Abdominal pain 0.0150536580105392 251 7 4 0.571428571428571 0.0159362549800797
HP HP:0000988 Skin rash 0.0162492123434633 114 14 4 0.285714285714286 0.0350877192982456
HP HP:0200042 Skin ulcer 0.0192502167975843 115 39 6 0.153846153846154 0.0521739130434783
HP HP:0032016 Abnormal sputum 0.0193303341971619 106 7 3 0.428571428571429 0.0283018867924528
HP HP:0000763 Sensory neuropathy 0.0204264344294751 182 10 4 0.4 0.021978021978022
HP HP:0001058 Poor wound healing 0.022128885269018 22 142 5 0.0352112676056338 0.227272727272727
HP HP:0001977 Abnormal thrombosis 0.0254080068586963 120 7 3 0.428571428571429 0.025
HP HP:0005421 Decreased serum complement C3 0.0254080068586963 11 73 3 0.0410958904109589 0.272727272727273
HP HP:0100519 Anuria 0.0268209474692718 12 69 3 0.0434782608695652 0.25
HP HP:0000093 Proteinuria 0.0268209474692718 168 30 6 0.2 0.0357142857142857
HP HP:0030878 Abnormality on pulmonary function testing 0.0268209474692718 128 7 3 0.428571428571429 0.0234375
HP HP:0001919 Acute kidney injury 0.0297517388183465 29 30 3 0.1 0.103448275862069
HP HP:0005575 Hemolytic-uremic syndrome 0.0297517388183465 13 69 3 0.0434782608695652 0.230769230769231
HP HP:0000083 Renal insufficiency 0.0298444702519304 337 7 4 0.571428571428571 0.0118694362017804
HP HP:0006530 Abnormal pulmonary Interstitial morphology 0.0300089758367774 140 7 3 0.428571428571429 0.0214285714285714
HP HP:0001824 Weight loss 0.0312801193238986 273 14 5 0.357142857142857 0.0183150183150183
HP HP:0020129 Abnormal urine protein level 0.0312801193238986 181 30 6 0.2 0.0331491712707182
HP HP:0011122 Abnormality of skin physiology 0.0323311235683915 430 14 6 0.428571428571429 0.013953488372093
HP HP:0005368 Abnormality of humoral immunity 0.0338157024984211 249 90 13 0.144444444444444 0.0522088353413655
HP HP:0007499 Recurrent staphylococcal infections 0.0339421245674122 16 142 4 0.028169014084507 0.25
HP HP:0031970 Abnormal blood urea nitrogen concentration 0.0342228989271843 15 69 3 0.0434782608695652 0.2
HP HP:0003138 Increased blood urea nitrogen 0.0342228989271843 15 69 3 0.0434782608695652 0.2
HP HP:0002829 Arthralgia 0.0343006653368488 161 7 3 0.428571428571429 0.0186335403726708
HP HP:0001426 Multifactorial inheritance 0.036497717496087 84 13 3 0.230769230769231 0.0357142857142857
HP HP:0000095 Abnormal renal glomerulus morphology 0.0370420638198328 158 79 9 0.113924050632911 0.0569620253164557
HP HP:0031263 Abnormal renal corpuscle morphology 0.0370420638198328 158 79 9 0.113924050632911 0.0569620253164557
HP HP:0000099 Glomerulonephritis 0.0385196030717872 33 72 4 0.0555555555555556 0.121212121212121
HP HP:0000790 Hematuria 0.0442565583153891 140 30 5 0.166666666666667 0.0357142857142857
HP HP:0012614 Abnormal urine cytology 0.0442565583153891 140 30 5 0.166666666666667 0.0357142857142857
HP HP:0030972 Abnormal systemic blood pressure 0.0447550601060927 423 7 4 0.571428571428571 0.00945626477541371
HP HP:0012575 Abnormal nephron morphology 0.0465491303092335 208 13 4 0.307692307692308 0.0192307692307692
HP HP:0100533 Inflammatory abnormality of the eye 0.0467700551667866 193 14 4 0.285714285714286 0.0207253886010363
HP HP:0002017 Nausea and vomiting 0.0493999353733419 442 7 4 0.571428571428571 0.00904977375565611
HPA HPA:0310443 lymph node; non-germinal center cells[High] 0.00614681179517513 1169 28 12 0.428571428571429 0.0102651839178785
HPA HPA:0310433 lymph node; germinal center cells[High] 0.0105217404765396 908 18 8 0.444444444444444 0.00881057268722467
HPA HPA:0300413 lung; macrophages[High] 0.0136783532867346 1224 19 9 0.473684210526316 0.00735294117647059
HPA HPA:0600433 tonsil; germinal center cells[High] 0.0192012923331754 1179 18 8 0.444444444444444 0.00678541136556404
HPA HPA:0600443 tonsil; non-germinal center cells[High] 0.0192012923331754 1271 126 29 0.23015873015873 0.022816679779701
HPA HPA:0530722 spleen; cells in white pulp[≥Medium] 0.0366747224979532 2645 18 11 0.611111111111111 0.00415879017013232
HPA HPA:0211092 fallopian tube; non-ciliated cells[≥Medium] 0.044722802532745 328 8 3 0.375 0.00914634146341463
KEGG KEGG:04612 Antigen processing and presentation 1.22127464049322e-18 69 58 16 0.275862068965517 0.231884057971014
KEGG KEGG:05150 Staphylococcus aureus infection 1.32314028430191e-16 87 108 19 0.175925925925926 0.218390804597701
KEGG KEGG:05310 Asthma 2.35392299587116e-15 27 16 8 0.5 0.296296296296296
KEGG KEGG:05330 Allograft rejection 2.35392299587116e-15 34 22 9 0.409090909090909 0.264705882352941
KEGG KEGG:05332 Graft-versus-host disease 4.44678027237109e-15 37 22 9 0.409090909090909 0.243243243243243
KEGG KEGG:04940 Type I diabetes mellitus 8.10918875886905e-15 40 22 9 0.409090909090909 0.225
KEGG KEGG:05320 Autoimmune thyroid disease 5.15372112605429e-14 49 22 9 0.409090909090909 0.183673469387755
KEGG KEGG:04672 Intestinal immune network for IgA production 1.11552746120153e-13 45 16 8 0.5 0.177777777777778
KEGG KEGG:05416 Viral myocarditis 1.46300232072544e-13 56 22 9 0.409090909090909 0.160714285714286
KEGG KEGG:05321 Inflammatory bowel disease 1.37870751109955e-12 62 16 8 0.5 0.129032258064516
KEGG KEGG:05140 Leishmaniasis 4.39735495752094e-12 72 16 8 0.5 0.111111111111111
KEGG KEGG:05152 Tuberculosis 5.80571997097884e-12 175 30 12 0.4 0.0685714285714286
KEGG KEGG:04145 Phagosome 7.19587658977202e-12 147 108 18 0.166666666666667 0.122448979591837
KEGG KEGG:05169 Epstein-Barr virus infection 8.86155276926354e-12 198 22 11 0.5 0.0555555555555556
KEGG KEGG:05323 Rheumatoid arthritis 1.64281006558198e-11 88 10 7 0.7 0.0795454545454545
KEGG KEGG:04658 Th1 and Th2 cell differentiation 1.67105566771649e-11 89 10 7 0.7 0.0786516853932584
KEGG KEGG:04640 Hematopoietic cell lineage 2.51725901094666e-11 95 10 7 0.7 0.0736842105263158
KEGG KEGG:04659 Th17 cell differentiation 4.55685512153191e-11 104 10 7 0.7 0.0673076923076923
KEGG KEGG:05145 Toxoplasmosis 6.04518754047036e-11 109 10 7 0.7 0.0642201834862385
KEGG KEGG:05322 Systemic lupus erythematosus 1.16934240939297e-10 132 108 16 0.148148148148148 0.121212121212121
KEGG KEGG:05166 Human T-cell leukemia virus 1 infection 4.11905674691179e-10 216 16 9 0.5625 0.0416666666666667
KEGG KEGG:04514 Cell adhesion molecules 4.19614440032979e-10 146 10 7 0.7 0.0479452054794521
KEGG KEGG:05164 Influenza A 1.13159962959956e-09 169 10 7 0.7 0.0414201183431953
KEGG KEGG:05168 Herpes simplex virus 1 infection 5.49508743206004e-09 494 18 11 0.611111111111111 0.0222672064777328
KEGG KEGG:04061 Viral protein interaction with cytokine and cytokine receptor 7.35776184410589e-06 98 116 10 0.0862068965517241 0.102040816326531
KEGG KEGG:05142 Chagas disease 7.52183445005993e-05 101 116 9 0.0775862068965517 0.0891089108910891
KEGG KEGG:04610 Complement and coagulation cascades 7.69455416462931e-05 85 106 8 0.0754716981132075 0.0941176470588235
KEGG KEGG:05340 Primary immunodeficiency 0.00018150223758503 37 139 6 0.0431654676258993 0.162162162162162
KEGG KEGG:04620 Toll-like receptor signaling pathway 0.00051437391312799 102 116 8 0.0689655172413793 0.0784313725490196
KEGG KEGG:04062 Chemokine signaling pathway 0.00190507223581262 190 116 10 0.0862068965517241 0.0526315789473684
KEGG KEGG:05133 Pertussis 0.0021539314305813 76 106 6 0.0566037735849057 0.0789473684210526
KEGG KEGG:04060 Cytokine-cytokine receptor interaction 0.00234657579459618 293 139 14 0.100719424460432 0.0477815699658703
KEGG KEGG:05163 Human cytomegalovirus infection 0.00323206951096406 223 55 7 0.127272727272727 0.031390134529148
KEGG KEGG:04650 Natural killer cell mediated cytotoxicity 0.0224306367806997 123 140 7 0.05 0.0569105691056911
KEGG KEGG:05170 Human immunodeficiency virus 1 infection 0.0313616855456319 210 110 8 0.0727272727272727 0.0380952380952381
KEGG KEGG:04623 Cytosolic DNA-sensing pathway 0.044554293880108 62 116 4 0.0344827586206897 0.0645161290322581
REAC REAC:R-HSA-877300 Interferon gamma signaling 1.81061899815035e-10 87 28 9 0.321428571428571 0.103448275862069
REAC REAC:R-HSA-2132295 MHC class II antigen presentation 1.81061899815035e-10 123 9 7 0.777777777777778 0.0569105691056911
REAC REAC:R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 2.47402229431335e-10 20 9 5 0.555555555555556 0.25
REAC REAC:R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 4.02328325675568e-10 23 9 5 0.555555555555556 0.217391304347826
REAC REAC:R-HSA-389948 PD-1 signaling 4.06434590824336e-10 24 9 5 0.555555555555556 0.208333333333333
REAC REAC:R-HSA-202433 Generation of second messenger molecules 2.57784594734153e-09 35 9 5 0.555555555555556 0.142857142857143
REAC REAC:R-HSA-168256 Immune System 6.75163557725682e-09 2139 131 59 0.450381679389313 0.0275829827021973
REAC REAC:R-HSA-1280218 Adaptive Immune System 1.83942220619752e-08 800 110 30 0.272727272727273 0.0375
REAC REAC:R-HSA-913531 Interferon Signaling 4.10979205140755e-08 191 28 9 0.321428571428571 0.0471204188481675
REAC REAC:R-HSA-388841 Costimulation by the CD28 family 4.55488147918002e-08 67 9 5 0.555555555555556 0.0746268656716418
REAC REAC:R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 9.40326920431257e-08 25 55 6 0.109090909090909 0.24
REAC REAC:R-HSA-202424 Downstream TCR signaling 2.64289930536803e-07 98 9 5 0.555555555555556 0.0510204081632653
REAC REAC:R-HSA-380108 Chemokine receptors bind chemokines 3.18018044608399e-07 57 116 9 0.0775862068965517 0.157894736842105
REAC REAC:R-HSA-202403 TCR signaling 6.31279829542906e-07 120 9 5 0.555555555555556 0.0416666666666667
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 1.57603608947987e-05 842 28 12 0.428571428571429 0.0142517814726841
REAC REAC:R-HSA-375276 Peptide ligand-binding receptors 2.74855632175286e-05 195 93 11 0.118279569892473 0.0564102564102564
REAC REAC:R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 6.69481342937954e-05 181 110 11 0.1 0.0607734806629834
REAC REAC:R-HSA-1236974 ER-Phagosome pathway 9.71507566373892e-05 83 55 6 0.109090909090909 0.072289156626506
REAC REAC:R-HSA-1236975 Antigen processing-Cross presentation 0.000256323884845887 99 55 6 0.109090909090909 0.0606060606060606
REAC REAC:R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 0.00128210536966669 328 116 13 0.112068965517241 0.0396341463414634
REAC REAC:R-HSA-6783783 Interleukin-10 signaling 0.0023927054027465 45 116 5 0.0431034482758621 0.111111111111111
REAC REAC:R-HSA-168249 Innate Immune System 0.00486427203686726 1073 125 26 0.208 0.0242311276794035
REAC REAC:R-HSA-418594 G alpha (i) signalling events 0.0071707114714193 401 116 13 0.112068965517241 0.0324189526184539
REAC REAC:R-HSA-977606 Regulation of Complement cascade 0.00942722220967428 101 72 5 0.0694444444444444 0.0495049504950495
REAC REAC:R-HSA-166658 Complement cascade 0.0139541758311425 111 72 5 0.0694444444444444 0.045045045045045
REAC REAC:R-HSA-8957275 Post-translational protein phosphorylation 0.0168035251057732 107 79 5 0.0632911392405063 0.0467289719626168
REAC REAC:R-HSA-500792 GPCR ligand binding 0.0197522841105671 459 102 12 0.117647058823529 0.0261437908496732
REAC REAC:R-HSA-166663 Initial triggering of complement 0.0215614852155949 76 72 4 0.0555555555555556 0.0526315789473684
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.025690251025298 446 139 14 0.100719424460432 0.031390134529148
REAC REAC:R-HSA-983169 Class I MHC mediated antigen processing & presentation 0.025690251025298 370 39 6 0.153846153846154 0.0162162162162162
REAC REAC:R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 0.026144394206492 124 79 5 0.0632911392405063 0.0403225806451613
REAC REAC:R-HSA-6803157 Antimicrobial peptides 0.0284000840373099 80 76 4 0.0526315789473684 0.05
REAC REAC:R-HSA-2424491 DAP12 signaling 0.0312291217629499 25 125 3 0.024 0.12
REAC REAC:R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors 0.049965642760134 95 79 4 0.0506329113924051 0.0421052631578947
TF TF:M07216_1 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT; match class: 1 2.73341916194622e-05 35 86 6 0.0697674418604651 0.171428571428571
TF TF:M07216 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT 2.73341916194622e-05 440 71 13 0.183098591549296 0.0295454545454545
TF TF:M09957 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN 3.05878638158925e-05 272 63 10 0.158730158730159 0.0367647058823529
TF TF:M04788 Factor: IRF-1; motif: STTTCACTTTCNNT 0.000140508239606209 536 63 12 0.19047619047619 0.0223880597014925
TF TF:M09629 Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN 0.000140508239606209 336 48 9 0.1875 0.0267857142857143
TF TF:M03916_1 Factor: PRDM1; motif: NRAAAGTGAAAGTNN; match class: 1 0.000145095425226125 50 48 5 0.104166666666667 0.1
TF TF:M07045 Factor: IRF-1; motif: NNRAAANNGAAASN 0.000237290140883584 535 68 12 0.176470588235294 0.0224299065420561
TF TF:M01882 Factor: IRF-2; motif: NNRAAAGTGAAASNNA 0.000388016218600897 258 38 7 0.184210526315789 0.0271317829457364
TF TF:M03882_1 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC; match class: 1 0.000388016218600897 714 55 12 0.218181818181818 0.0168067226890756
TF TF:M09956 Factor: IRF-1; motif: NAAANNGAAASTGAAASNRN 0.000453180797677244 317 63 9 0.142857142857143 0.028391167192429
TF TF:M03545_1 Factor: c-Rel; motif: NGGGAATYTCCN; match class: 1 0.000453180797677244 1011 57 14 0.245614035087719 0.0138476755687438
TF TF:M00772_1 Factor: IRF; motif: RRAANTGAAASYGNV; match class: 1 0.000562229124242404 57 63 5 0.0793650793650794 0.087719298245614
TF TF:M00972 Factor: IRF; motif: RAAANTGAAAN 0.000614086522584358 1979 130 32 0.246153846153846 0.0161697827185447
TF TF:M07045_1 Factor: IRF-1; motif: NNRAAANNGAAASN; match class: 1 0.000700256964807983 19 24 3 0.125 0.157894736842105
TF TF:M11684 Factor: IRF-8; motif: NYGAAACYGAAACTN 0.00071272589345326 4664 142 59 0.415492957746479 0.0126500857632933
TF TF:M10094_1 Factor: RelA-p65; motif: NWGGGRATTTCCMN; match class: 1 0.000764187828094569 242 18 5 0.277777777777778 0.0206611570247934
TF TF:M11664 Factor: IRF-2; motif: NGAAASYGAAAS 0.000764187828094569 1651 68 19 0.279411764705882 0.0115081768625076
TF TF:M07464_1 Factor: Prep-1; motif: GRBTGANAGATN; match class: 1 0.000924245677485883 607 101 14 0.138613861386139 0.0230642504118616
TF TF:M08775_1 Factor: IRF-2; motif: NAANYGAAASYR; match class: 1 0.000989176342232823 2761 137 40 0.291970802919708 0.0144875045273452
TF TF:M02013_1 Factor: HNF-1alpha; motif: RGTTAATNWTT; match class: 1 0.00104573734601507 90 90 6 0.0666666666666667 0.0666666666666667
TF TF:M00790 Factor: HNF-1; motif: WRGTTAATNATTAACNNN 0.00104573734601507 2793 90 30 0.333333333333333 0.0107411385606874
TF TF:M08887 Factor: IRF; motif: NNGAAANTGAAANN 0.00104573734601507 1267 27 10 0.37037037037037 0.00789265982636148
TF TF:M00772 Factor: IRF; motif: RRAANTGAAASYGNV 0.00120193609523361 1029 121 20 0.165289256198347 0.0194363459669582
TF TF:M01224_1 Factor: P50:RELA-P65; motif: GGANTTYCCCWN; match class: 1 0.00120193609523361 236 133 10 0.075187969924812 0.0423728813559322
TF TF:M07044 Factor: HNF-1alpha; motif: NGNNAAWNATTAACNN 0.00120193609523361 1678 90 22 0.244444444444444 0.0131108462455304
TF TF:M00194 Factor: NF-kappaB; motif: NGGGGAMTTTCCNN 0.00138495270892253 2412 137 36 0.262773722627737 0.0149253731343284
TF TF:M11682 Factor: IRF-8; motif: NYGAAASYGAAACYN 0.00141559739899348 3795 39 20 0.512820512820513 0.00527009222661397
TF TF:M00453 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN 0.00141559739899348 3082 39 18 0.461538461538462 0.00584036340038936
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 0.00141559739899348 1657 23 10 0.434782608695652 0.00603500301750151
TF TF:M00287 Factor: NF-Y; motif: NNNRRCCAATSRGNNN 0.00141559739899348 1635 23 10 0.434782608695652 0.00611620795107034
TF TF:M01224 Factor: P50:RELA-P65; motif: GGANTTYCCCWN 0.00141559739899348 2329 99 28 0.282828282828283 0.0120223271790468
TF TF:M10094 Factor: RelA-p65; motif: NWGGGRATTTCCMN 0.00141559739899348 2429 39 16 0.41025641025641 0.00658707286949362
TF TF:M03882 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC 0.00141559739899348 4474 140 55 0.392857142857143 0.0122932498882432
TF TF:M07222 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR 0.00159698879791213 714 22 7 0.318181818181818 0.00980392156862745
TF TF:M00132 Factor: HNF-1alpha; motif: GGTTAATNWTTAMCN 0.00166989491727831 840 105 16 0.152380952380952 0.019047619047619
TF TF:M01884_1 Factor: IRF-7; motif: AAGWGAA; match class: 1 0.00166989491727831 4556 142 56 0.394366197183099 0.0122914837576822
TF TF:M07314_1 Factor: Blimp-1; motif: RGRAAGNGAAAG; match class: 1 0.00168669350643822 118 48 5 0.104166666666667 0.0423728813559322
TF TF:M04498_1 Factor: VDR; motif: GRGTTCATYGRGTTCA; match class: 1 0.00168669350643822 876 13 6 0.461538461538462 0.00684931506849315
TF TF:M04849_1 Factor: RelA-p65; motif: AAASTCCC; match class: 1 0.00182126093739654 1170 39 11 0.282051282051282 0.0094017094017094
TF TF:M03541_1 Factor: C-Jun; motif: TGACTC; match class: 1 0.00184902274708737 4221 51 25 0.490196078431373 0.00592276711679697
TF TF:M10460_1 Factor: ZNF273; motif: GAGAGGAGCTAC; match class: 1 0.00201595268925726 5829 12 11 0.916666666666667 0.00188711614342083
TF TF:M04557_1 Factor: SRY; motif: TCAATAMCATTGA; match class: 1 0.00201595268925726 5015 85 40 0.470588235294118 0.00797607178464606
TF TF:M01203 Factor: SPI1; motif: NNAAWGNGGAASTNNNN 0.00216177187239716 2643 136 37 0.272058823529412 0.0139992432841468
TF TF:M00208_1 Factor: NF-kappaB; motif: NGGGACTTTCCA; match class: 1 0.0022469782860009 604 19 6 0.315789473684211 0.00993377483443709
TF TF:M02162 Factor: HNF1A; motif: GGTTAATNATTAMC 0.0022469782860009 1193 105 19 0.180952380952381 0.0159262363788768
TF TF:M11034 Factor: Six-3; motif: NNGTATCRNN 0.00237812263102106 3725 142 48 0.338028169014085 0.0128859060402685
TF TF:M11383 Factor: ESE-1; motif: ACCAGGAAGTANNNNNNNAAWAA 0.00251991362466772 3886 137 48 0.35036496350365 0.0123520329387545
TF TF:M11665_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 0.00252147525005477 246 27 5 0.185185185185185 0.0203252032520325
TF TF:M11685_1 Factor: IRF-8; motif: NCGAAACYGAAACYN; match class: 1 0.00253771173090677 118 27 4 0.148148148148148 0.0338983050847458
TF TF:M04082 Factor: POU3F3; motif: WTNAATAWKNAW 0.00295313226215439 3600 124 42 0.338709677419355 0.0116666666666667
TF TF:M03563_1 Factor: RelA-p65; motif: GGGANTTTCCNN; match class: 1 0.00299098408840206 876 97 15 0.154639175257732 0.0171232876712329
TF TF:M07302 Factor: NF-Y; motif: RGCCAATCRGN 0.00308299417354564 1576 22 9 0.409090909090909 0.00571065989847716
TF TF:M09649_1 Factor: Blimp-1; motif: RAAAGTGAAAGTNN; match class: 1 0.00313970476572362 10 121 3 0.0247933884297521 0.3
TF TF:M11686 Factor: IRF-4; motif: NYGAAASYGAAACYN 0.00313970476572362 3391 39 18 0.461538461538462 0.00530816868180478
TF TF:M02078 Factor: SPI1; motif: NGRGGAAGTN 0.00318979646215966 3506 136 44 0.323529411764706 0.0125499144324016
TF TF:M09902 Factor: ESE-1; motif: NNANVAGGAAGTNN 0.00340537624754432 3200 135 41 0.303703703703704 0.0128125
TF TF:M10058 Factor: Six-2; motif: KGAAAYNTGAKMC 0.00361678825626571 1516 88 19 0.215909090909091 0.012532981530343
TF TF:M00971 Factor: Ets; motif: ACTTCCTS 0.00365864923683653 2349 134 33 0.246268656716418 0.0140485312899106
TF TF:M10057 Factor: Six-1; motif: TGWAAYNTGAKMCN 0.00373082980337897 594 82 11 0.134146341463415 0.0185185185185185
TF TF:M09960 Factor: IRF-8; motif: NNAARRGGAASTGAAASTNN 0.00414804034969475 282 114 9 0.0789473684210526 0.0319148936170213
TF TF:M09941_1 Factor: GR; motif: RGNACANMNTGTNCY; match class: 1 0.00444463274242692 2046 68 19 0.279411764705882 0.00928641251221896
TF TF:M00053 Factor: c-Rel; motif: SGGRNTTTCC 0.00471807839012039 3672 41 19 0.463414634146341 0.00517429193899782
TF TF:M10040_1 Factor: Blimp-1; motif: RAAAGNGAAAGTNN; match class: 1 0.00473926802536545 12 121 3 0.0247933884297521 0.25
TF TF:M09629_1 Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN; match class: 1 0.00473926802536545 29 48 3 0.0625 0.103448275862069
TF TF:M00747_1 Factor: IRF-1; motif: TTCACTT; match class: 1 0.00516864197819206 933 56 11 0.196428571428571 0.0117899249732047
TF TF:M08359 Factor: HOXD12:Elk-1; motif: NRNCGGAAGTCGTAAAN 0.00543043755607447 6152 135 64 0.474074074074074 0.0104031209362809
TF TF:M11687 Factor: IRF-4; motif: NCGAAACCGAAACYN 0.00544143441359496 3595 39 18 0.461538461538462 0.00500695410292072
TF TF:M10073 Factor: PU.1; motif: NRAAAGAGGAAGTGRNN 0.00544143441359496 2416 134 33 0.246268656716418 0.013658940397351
TF TF:M09589 Factor: AR; motif: NGNACANNNTGTTCYNN 0.00552447650580383 5130 71 34 0.47887323943662 0.00662768031189084
TF TF:M11665 Factor: IRF-2; motif: NGAAASYGAAAS 0.00633986011937478 2396 142 34 0.23943661971831 0.0141903171953255
TF TF:M03795 Factor: LXR;; motif: NTGACCKNNAGTRACCYNN 0.00640867178195993 6570 121 61 0.504132231404959 0.00928462709284627
TF TF:M00974 Factor: SMAD; motif: TNGNCAGACWN 0.00662126968076255 4535 41 21 0.51219512195122 0.00463065049614112
TF TF:M09941 Factor: GR; motif: RGNACANMNTGTNCY 0.00667474627179206 5863 74 38 0.513513513513513 0.00648132355449429
TF TF:M03872 Factor: HNF-1beta; motif: GTTAATYATTAACY 0.00692087215736139 4145 90 35 0.388888888888889 0.00844390832328106
TF TF:M01870 Factor: C-ets-1; motif: AGGAAGN 0.00708507982799062 6837 141 71 0.50354609929078 0.010384671639608
TF TF:M03579 Factor: PEA3; motif: AGGAAGT 0.00708507982799062 6837 141 71 0.50354609929078 0.010384671639608
TF TF:M02278 Factor: SPI1; motif: AGGAAGT 0.00708507982799062 6837 141 71 0.50354609929078 0.010384671639608
TF TF:M07382 Factor: Fli-1; motif: MGGAAGT 0.00708507982799062 6837 141 71 0.50354609929078 0.010384671639608
TF TF:M00052 Factor: NF-kappaB; motif: GGGRATTTCC 0.00715583093621843 1874 97 22 0.22680412371134 0.0117395944503735
TF TF:M07221 Factor: NF-kappaB1; motif: KGGRNTTTCCM 0.00715583093621843 2417 38 14 0.368421052631579 0.0057923045097228
TF TF:M11376 Factor: Spi-B; motif: RAAWGRGGAAGTN 0.00718661986154242 729 130 15 0.115384615384615 0.0205761316872428
TF TF:M10005 Factor: NF-YA; motif: NYRRCCAATCAGAR 0.00718661986154242 2225 23 10 0.434782608695652 0.00449438202247191
TF TF:M11374_1 Factor: Spi-B; motif: NAWGRGGAAGTR; match class: 1 0.00727747638698308 202 104 7 0.0673076923076923 0.0346534653465347
TF TF:M09903 Factor: elf5; motif: NNNANSAGGAAGTNN 0.00727747638698308 1243 134 21 0.156716417910448 0.0168946098149638
TF TF:M00655 Factor: PEA3; motif: ACWTCCK 0.00727747638698308 9452 116 76 0.655172413793103 0.00804062632247144
TF TF:M09589_1 Factor: AR; motif: NGNACANNNTGTTCYNN; match class: 1 0.00758895934272008 1159 66 13 0.196969696969697 0.0112165660051769
TF TF:M00063 Factor: IRF-2; motif: GAAAAGYGAAASY 0.00758895934272008 685 124 14 0.112903225806452 0.0204379562043796
TF TF:M04849 Factor: RelA-p65; motif: AAASTCCC 0.00819534201514056 6240 39 24 0.615384615384615 0.00384615384615385
TF TF:M03872_1 Factor: HNF-1beta; motif: GTTAATYATTAACY; match class: 1 0.00824563703219121 729 90 12 0.133333333333333 0.0164609053497942
TF TF:M01011 Factor: HNF-1; motif: NNNNGNTAAWNATTAACYNNN 0.00833207685970652 2376 90 24 0.266666666666667 0.0101010101010101
TF TF:M00655_1 Factor: PEA3; motif: ACWTCCK; match class: 1 0.00833207685970652 2934 140 38 0.271428571428571 0.0129516019086571
TF TF:M01884 Factor: IRF-7; motif: AAGWGAA 0.00866163454390193 10868 142 100 0.704225352112676 0.00920132499079867
TF TF:M09745 Factor: HELIOS; motif: RNARRRGGAASTGARAN 0.00891975898138276 3582 125 40 0.32 0.0111669458403127
TF TF:M00687 Factor: alpha-CP1; motif: CAGCCAATGAG 0.00899083502659043 2326 23 10 0.434782608695652 0.00429922613929493
TF TF:M09915_1 Factor: PEA3; motif: NNCAGGAARNN; match class: 1 0.00899083502659043 5690 126 56 0.444444444444444 0.00984182776801406
TF TF:M08887_1 Factor: IRF; motif: NNGAAANTGAAANN; match class: 1 0.00899083502659043 73 27 3 0.111111111111111 0.0410958904109589
TF TF:M00774 Factor: NF-kappaB; motif: NGGGANTTYCCMNNNN 0.00905692575765717 1818 89 20 0.224719101123595 0.011001100110011
TF TF:M09839 Factor: ATF4; motif: ATTGCATCAT 0.00905692575765717 2145 4 4 1 0.00186480186480186
TF TF:M09816 Factor: NFYA; motif: RRCCAATCAGN 0.00920467991431912 1969 22 9 0.409090909090909 0.00457084814626714
TF TF:M04476_1 Factor: NR3C1; motif: NRGWACAYNRTGTWCYN; match class: 1 0.00930411591759257 5349 71 34 0.47887323943662 0.00635632828566087
TF TF:M00672_1 Factor: TEF; motif: ATGTTWAYATAA; match class: 1 0.00946759246089655 1824 76 18 0.236842105263158 0.00986842105263158
TF TF:M11683 Factor: IRF-8; motif: NCGAAACCGAAACYN 0.00946759246089655 4690 28 16 0.571428571428571 0.00341151385927505
TF TF:M09733 Factor: STAT2; motif: NRGAAANNGAAACTNA 0.00951656117198952 2842 73 23 0.315068493150685 0.00809289232934553
TF TF:M09733_1 Factor: STAT2; motif: NRGAAANNGAAACTNA; match class: 1 0.00970059127170621 367 63 7 0.111111111111111 0.0190735694822888
TF TF:M03826_1 Factor: HNF-1beta; motif: NNNYAAHCATTAACYN; match class: 1 0.00970059127170621 328 70 7 0.1 0.0213414634146341
TF TF:M07204 Factor: AR; motif: ARGAACANNNTGTNC 0.00970059127170621 4906 101 42 0.415841584158416 0.00856094578067672
TF TF:M03866 Factor: c-Fos:c-Jun; motif: NTGACTCAN 0.00970059127170621 1626 123 23 0.186991869918699 0.0141451414514145
TF TF:M11908_1 Factor: POU3F2; motif: TAATKAGNNNNTAATKA; match class: 1 0.00997109232498862 1278 89 16 0.179775280898876 0.0125195618153365
TF TF:M04750_1 Factor: GR; motif: RGRACATTNTGTYC; match class: 1 0.00997109232498862 1704 68 16 0.235294117647059 0.00938967136150235
TF TF:M10949 Factor: rax; motif: YTAATTAN 0.00997109232498862 267 39 5 0.128205128205128 0.0187265917602996
TF TF:M07044_1 Factor: HNF-1alpha; motif: NGNNAAWNATTAACNN; match class: 1 0.0100007303155919 147 70 5 0.0714285714285714 0.0340136054421769
TF TF:M00351 Factor: GATA-3; motif: ANAGATMWWA 0.0103667003592349 2729 96 27 0.28125 0.00989373396848662
TF TF:M01172 Factor: PU.1; motif: NNNNYYYACTTCCTCTTTY 0.0104079371458292 4281 136 48 0.352941176470588 0.0112123335669236
TF TF:M11847_1 Factor: GR; motif: RGWACATWATGTWCY; match class: 1 0.0107571098391437 4066 74 29 0.391891891891892 0.00713231677324151
TF TF:M11268_1 Factor: JunD; motif: NATGASTCATS; match class: 1 0.0108662120598084 1837 11 6 0.545454545454545 0.00326619488296135
TF TF:M10841 Factor: HOXC13; motif: NCCAATAAAAC 0.0117039055034776 102 23 3 0.130434782608696 0.0294117647058824
TF TF:M10042 Factor: PR; motif: RGNACATTYTGTNCTN 0.0117039055034776 3203 71 24 0.338028169014085 0.00749297533562285
TF TF:M00194_1 Factor: NF-kappaB; motif: NGGGGAMTTTCCNN; match class: 1 0.0117039055034776 385 16 4 0.25 0.0103896103896104
TF TF:M10848 Factor: HOXB13; motif: NCCAATAAAAC 0.0117039055034776 102 23 3 0.130434782608696 0.0294117647058824
TF TF:M01896 Factor: C/EBPbeta; motif: TKNNGCAANN 0.0118825541765623 4512 117 44 0.376068376068376 0.00975177304964539
TF TF:M04328_1 Factor: GSX2; motif: NNYMATTANN; match class: 1 0.0120103296616813 3836 86 31 0.36046511627907 0.00808133472367049
TF TF:M08626 Factor: TEF-3:C/EBPbeta; motif: RTTGCGYAAYNNNNNGGAATGY 0.0123369049938858 7003 16 13 0.8125 0.00185634727973726
TF TF:M11682_1 Factor: IRF-8; motif: NYGAAASYGAAACYN; match class: 1 0.0124044908939385 543 33 6 0.181818181818182 0.0110497237569061
TF TF:M00210_1 Factor: OCT-x; motif: CTNATTTGCATAY; match class: 1 0.0124044908939385 700 73 10 0.136986301369863 0.0142857142857143
TF TF:M01279 Factor: IRF-3; motif: NBNBTTTCSCTTT 0.0124044908939385 1647 39 11 0.282051282051282 0.00667880995749848
TF TF:M01066 Factor: Blimp-1; motif: NRGRAAGKGAAAGKRN 0.0125403765201209 411 28 5 0.178571428571429 0.0121654501216545
TF TF:M03557_1 Factor: P50; motif: GGRRANTCCCNN; match class: 1 0.012545121275095 1292 91 16 0.175824175824176 0.0123839009287926
TF TF:M10006 Factor: NF-YC; motif: NNRRCCAATCAGNR 0.0125705279006505 2510 23 10 0.434782608695652 0.00398406374501992
TF TF:M11678 Factor: IRF-7; motif: NNGAAAGTGAAANTR 0.012914716433959 179 63 5 0.0793650793650794 0.0279329608938547
TF TF:M04202 Factor: CEBPD; motif: RTTRCGCAAY 0.0131813512404095 5031 6 6 1 0.00119260584376863
TF TF:M07204_1 Factor: AR; motif: ARGAACANNNTGTNC; match class: 1 0.0139479100363878 963 110 15 0.136363636363636 0.0155763239875389
TF TF:M08836_1 Factor: OCT-2; motif: ATGMATATGCWAAT; match class: 1 0.0139725529914842 822 76 11 0.144736842105263 0.01338199513382
TF TF:M02077_1 Factor: Spic; motif: NGNGGAASTN; match class: 1 0.0139725529914842 2260 136 30 0.220588235294118 0.0132743362831858
TF TF:M03995 Factor: SPIB; motif: NAAAAGMGGAAGTN 0.013998693611251 759 124 14 0.112903225806452 0.0184453227931489
TF TF:M08775 Factor: IRF-2; motif: NAANYGAAASYR 0.0141534292196515 8370 142 81 0.570422535211268 0.00967741935483871
TF TF:M00054 Factor: NF-kappaB; motif: GGGAMTTYCC 0.0144015899941496 2444 93 24 0.258064516129032 0.00981996726677578
TF TF:M00531 Factor: nerf; motif: YRNCAGGAAGYRGSTBDS 0.0146360363997745 7615 126 68 0.53968253968254 0.00892974392646093
TF TF:M10074 Factor: Spi-B; motif: NRAAAGAGGAAGTGARA 0.0147217440445591 1611 130 23 0.176923076923077 0.0142768466790813
TF TF:M11686_1 Factor: IRF-4; motif: NYGAAASYGAAACYN; match class: 1 0.0147217440445591 452 27 5 0.185185185185185 0.0110619469026549
TF TF:M04750 Factor: GR; motif: RGRACATTNTGTYC 0.0147309486844618 5323 71 33 0.464788732394366 0.00619951155363517
TF TF:M08906 Factor: TR4; motif: NCCCTGACCYB 0.015075877625988 4530 66 28 0.424242424242424 0.00618101545253863
TF TF:M00790_1 Factor: HNF-1; motif: WRGTTAATNATTAACNNN; match class: 1 0.0151656078485393 372 70 7 0.1 0.0188172043010753
TF TF:M00984 Factor: PEBP; motif: GNTNACCACARANNK 0.0158919035764894 1346 73 14 0.191780821917808 0.0104011887072808
TF TF:M11664_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 0.0159198982930804 140 48 4 0.0833333333333333 0.0285714285714286
TF TF:M05304 Factor: Zbtb5; motif: AGGRAGCTTC 0.0159198982930804 299 41 5 0.121951219512195 0.0167224080267559
TF TF:M07355 Factor: GR; motif: AGAACAN 0.0161635626802812 5862 124 55 0.443548387096774 0.00938246332309792
TF TF:M02013 Factor: HNF-1alpha; motif: RGTTAATNWTT 0.0166687743613731 1522 105 19 0.180952380952381 0.0124835742444152
TF TF:M11687_1 Factor: IRF-4; motif: NCGAAACCGAAACYN; match class: 1 0.0171227066335145 474 27 5 0.185185185185185 0.0105485232067511
TF TF:M11989 Factor: NFATc3; motif: RYGGAAANNNNNNNTTTCCRY 0.0171227066335145 1238 17 6 0.352941176470588 0.00484652665589661
TF TF:M00203 Factor: GATA-X; motif: NGATAAGNMNN 0.0172192162354265 3713 99 33 0.333333333333333 0.0088876918933477
TF TF:M07314 Factor: Blimp-1; motif: RGRAAGNGAAAG 0.0172192162354265 1460 39 10 0.256410256410256 0.00684931506849315
TF TF:M11388 Factor: elf5; motif: AANRAGGAAGTR 0.017373695402965 660 130 13 0.1 0.0196969696969697
TF TF:M08897 Factor: SMAD; motif: TGTCTGNNN 0.0174674382476375 4543 28 15 0.535714285714286 0.00330178296279991
TF TF:M10042_1 Factor: PR; motif: RGNACATTYTGTNCTN; match class: 1 0.0174674382476375 998 66 11 0.166666666666667 0.0110220440881764
TF TF:M09777_1 Factor: NR1H4; motif: NNAATGACCNN; match class: 1 0.0174674382476375 522 25 5 0.2 0.00957854406130268
TF TF:M01889 Factor: Smad4; motif: TGTCTGN 0.0174674382476375 5247 56 27 0.482142857142857 0.00514579759862779
TF TF:M11677 Factor: IRF-3; motif: NGGAAACNGAAACCGAAACN 0.0176409123735843 470 137 11 0.0802919708029197 0.0234042553191489
TF TF:M01883_1 Factor: IRF-4; motif: GAAARTA; match class: 1 0.0176409123735843 2948 94 27 0.287234042553192 0.00915875169606513
TF TF:M00751 Factor: AML1; motif: TGTGGT 0.0185416124720562 12126 140 105 0.75 0.0086590796635329
TF TF:M11685 Factor: IRF-8; motif: NCGAAACYGAAACYN 0.0185416124720562 1617 133 23 0.172932330827068 0.0142238713667285
TF TF:M00271 Factor: AML1a; motif: TGTGGT 0.0185416124720562 12126 140 105 0.75 0.0086590796635329
TF TF:M02084 Factor: AML1; motif: TGTGGT 0.0185416124720562 12126 140 105 0.75 0.0086590796635329
TF TF:M11814_1 Factor: T3R-beta; motif: NRGGTCAAAGGTCRN; match class: 1 0.0185416124720562 7275 33 22 0.666666666666667 0.00302405498281787
TF TF:M06132 Factor: ZNF823; motif: NYYACCAGCCCT 0.0187535696175238 55 132 4 0.0303030303030303 0.0727272727272727
TF TF:M10716 Factor: HOXA4; motif: RTMATTAN 0.0187535696175238 4050 141 46 0.326241134751773 0.011358024691358
TF TF:M04472 Factor: COUP-TF1; motif: RRGGTCAAAGGTCAN 0.0187535696175238 1706 47 12 0.25531914893617 0.00703399765533412
TF TF:M00747 Factor: IRF-1; motif: TTCACTT 0.0189838596959346 5208 38 20 0.526315789473684 0.00384024577572965
TF TF:M04690_1 Factor: C/EBPbeta; motif: RTTGCGCAA; match class: 1 0.0193039012752159 3547 117 36 0.307692307692308 0.0101494220468001
TF TF:M09630 Factor: IRF-4; motif: RRRGRGGAASTGARAS 0.0193039012752159 954 105 14 0.133333333333333 0.0146750524109015
TF TF:M02106 Factor: NF-YA; motif: CRGCCAATCAGNRN 0.0193039012752159 1741 23 8 0.347826086956522 0.00459506031016657
TF TF:M09959 Factor: IRF-4; motif: NAANGRGGAASTGAAASN 0.0193894953788167 3386 140 40 0.285714285714286 0.0118133490844654
TF TF:M11908 Factor: POU3F2; motif: TAATKAGNNNNTAATKA 0.0198041361591128 3695 89 30 0.337078651685393 0.0081190798376184
TF TF:M02016 Factor: HNF-4alpha; motif: GNNCAAAGKYCANNN 0.0198041361591128 2384 26 10 0.384615384615385 0.00419463087248322
TF TF:M01124_1 Factor: Oct-4; motif: ATTGWSWTGCWAAWN; match class: 1 0.0198264002589769 1757 124 23 0.185483870967742 0.0130904951622083
TF TF:M11390_1 Factor: Erg; motif: NACAGGAARTN; match class: 1 0.0207205809322179 247 114 7 0.0614035087719298 0.0283400809716599
TF TF:M09745_1 Factor: HELIOS; motif: RNARRRGGAASTGARAN; match class: 1 0.0210930979093725 495 114 10 0.087719298245614 0.0202020202020202
TF TF:M00192_1 Factor: GR; motif: NNNNNNCNNTNTGTNCTNN; match class: 1 0.0215368489891165 1974 42 12 0.285714285714286 0.0060790273556231
TF TF:M11942 Factor: POU4F3; motif: ATGMATWATGCAT 0.0215368489891165 595 131 12 0.0916030534351145 0.0201680672268908
TF TF:M07230 Factor: TAL1::GATA1; motif: NTTATCWNNNNNNNNCAG 0.0216882888791158 3702 138 42 0.304347826086957 0.0113452188006483
TF TF:M03563 Factor: RelA-p65; motif: GGGANTTTCCNN 0.0218451057066683 4643 89 35 0.393258426966292 0.0075382295929356
TF TF:M00185 Factor: NF-Y; motif: TRRCCAATSRN 0.0218451057066683 870 10 4 0.4 0.00459770114942529
TF TF:M04485 Factor: RARG; motif: RAGGTCAASYARAGGTCA 0.0220306217521184 5105 109 44 0.403669724770642 0.00861900097943193
TF TF:M04197 Factor: ATF4; motif: NNATGAYGCAATM 0.0222345391579085 2164 5 4 0.8 0.00184842883548983
TF TF:M04453 Factor: AR; motif: RGGWACAYNGTGTWCYN 0.0223751165757493 7164 72 40 0.555555555555556 0.00558347292015634
TF TF:M02219_1 Factor: NR3C1; motif: RRGAACATWMYGTYCTRN; match class: 1 0.0225133236262402 1458 16 6 0.375 0.00411522633744856
TF TF:M08471 Factor: Fli-1:HOXB13; motif: NNCGGAARYNRTWAA 0.0225133236262402 5224 95 40 0.421052631578947 0.00765696784073507
TF TF:M04299 Factor: Dlx-1; motif: NNTAATTANN 0.0225463919667156 2524 84 22 0.261904761904762 0.00871632329635499
TF TF:M01197 Factor: Elf5; motif: WNAAGGAARTW 0.0225463919667156 2095 25 9 0.36 0.00429594272076372
TF TF:M00432 Factor: TTF1; motif: ASTCAAGTRK 0.0225463919667156 5394 81 36 0.444444444444444 0.00667408231368187
TF TF:M09631 Factor: JunB; motif: NNNTGAGTCAY 0.0225463919667156 1915 123 24 0.195121951219512 0.012532637075718
TF TF:M00106_1 Factor: CDP; motif: NATYGATSSS; match class: 1 0.0225463919667156 1686 92 18 0.195652173913043 0.0106761565836299
TF TF:M12075_1 Factor: ZNF342; motif: TRSTGGACRNT; match class: 1 0.0225463919667156 1319 12 5 0.416666666666667 0.00379075056861259
TF TF:M00190 Factor: C/EBP; motif: NNATTGCNNAANNN 0.0225463919667156 5586 138 57 0.41304347826087 0.0102040816326531
TF TF:M09737 Factor: ZNF644; motif: TCCWGCCTCTSN 0.0225463919667156 7275 52 31 0.596153846153846 0.00426116838487973
TF TF:M04393 Factor: LMX1B; motif: NYAATTAN 0.0226458680687345 2301 86 21 0.244186046511628 0.0091264667535854
TF TF:M01203_1 Factor: SPI1; motif: NNAAWGNGGAASTNNNN; match class: 1 0.0226458680687345 211 100 6 0.06 0.028436018957346
TF TF:M07476 Factor: Lhx8; motif: TGATTG 0.0226458680687345 9096 79 51 0.645569620253165 0.00560686015831135
TF TF:M09621 Factor: GATA-1; motif: NTGNNNNNNNSAGATAAGR 0.0240834578537819 5505 94 41 0.436170212765957 0.00744777475022707
TF TF:M10097 Factor: AP-4; motif: YCAGCTGNKN 0.0241380347635254 6018 15 11 0.733333333333333 0.00182784978398139
TF TF:M11084 Factor: SREBP-2; motif: ATCACMCCAY 0.0241380347635254 3285 110 32 0.290909090909091 0.00974124809741248
TF TF:M09726_1 Factor: GATAD2A; motif: CCTKTG; match class: 1 0.0251358600594461 9052 130 78 0.6 0.00861688024745912
TF TF:M09652 Factor: rfx5; motif: STCNNCWGTTGCYRGGNNRA 0.0251358600594461 981 16 5 0.3125 0.00509683995922528
TF TF:M11321 Factor: C/EBPdelta; motif: NRTTGCGYAAYN 0.0251358600594461 5597 18 12 0.666666666666667 0.00214400571734858
TF TF:M01870_1 Factor: C-ets-1; motif: AGGAAGN; match class: 1 0.0252465684284624 1496 140 22 0.157142857142857 0.0147058823529412
TF TF:M04279 Factor: ALX3; motif: NNYAATTANN 0.0252465684284624 3934 86 30 0.348837209302326 0.00762582613116421
TF TF:M07382_1 Factor: Fli-1; motif: MGGAAGT; match class: 1 0.0252465684284624 1496 140 22 0.157142857142857 0.0147058823529412
TF TF:M03579_1 Factor: PEA3; motif: AGGAAGT; match class: 1 0.0252465684284624 1496 140 22 0.157142857142857 0.0147058823529412
TF TF:M04053 Factor: NFATc1; motif: TTTTCCATGGAAAN 0.0252465684284624 8535 141 80 0.567375886524823 0.00937316930287053
TF TF:M02278_1 Factor: SPI1; motif: AGGAAGT; match class: 1 0.0252465684284624 1496 140 22 0.157142857142857 0.0147058823529412
TF TF:M04327 Factor: GSX1; motif: NNYMATTANN 0.0259434698063793 5709 86 39 0.453488372093023 0.00683131897004729
TF TF:M00672 Factor: TEF; motif: ATGTTWAYATAA 0.0263907695766016 5921 94 43 0.457446808510638 0.00726228677588245
TF TF:M08979_1 Factor: VDR; motif: NRRGTTCA; match class: 1 0.0263907695766016 709 13 4 0.307692307692308 0.00564174894217207
TF TF:M08426 Factor: TEF-3:Gscl; motif: GGWATGTTAATCSG 0.026492382285989 331 12 3 0.25 0.00906344410876133
TF TF:M00622 Factor: C/EBPgamma; motif: YTBATTTCARAAW 0.026557874232541 6887 125 61 0.488 0.0088572673152316
TF TF:M01723 Factor: SATB1; motif: AKWAWTAAHGRYMNWW 0.026557874232541 3229 60 20 0.333333333333333 0.0061938680706101
TF TF:M09625_1 Factor: GR; motif: RGNACANKNTGTNCY; match class: 1 0.026557874232541 4205 54 22 0.407407407407407 0.00523186682520809
TF TF:M11816_1 Factor: T3R-beta; motif: NRGGTCAAAGGTCAN; match class: 1 0.026557874232541 4798 18 11 0.611111111111111 0.00229262192580242
TF TF:M00809 Factor: FOX; motif: KWTTGTTTRTTTW 0.026557874232541 3746 75 26 0.346666666666667 0.00694073678590497
TF TF:M10752 Factor: HOXA1; motif: NTCRTTAN 0.026557874232541 1460 74 14 0.189189189189189 0.00958904109589041
TF TF:M10715 Factor: HOXA4; motif: RTCRTTAN 0.026557874232541 1460 74 14 0.189189189189189 0.00958904109589041
TF TF:M01728_1 Factor: EAR2; motif: YGNNCTTTGNCCTK; match class: 1 0.026557874232541 1256 8 4 0.5 0.00318471337579618
TF TF:M10704 Factor: HoxA5; motif: RTCATTAN 0.026557874232541 5447 122 50 0.409836065573771 0.00917936478795667
TF TF:M11378 Factor: ESE-1; motif: ACMAGGAAGTANNNNNNNWWAWW 0.026557874232541 3049 26 11 0.423076923076923 0.00360774024270253
TF TF:M10721 Factor: HOXB4; motif: RTCRTTAN 0.026557874232541 1460 74 14 0.189189189189189 0.00958904109589041
TF TF:M08836 Factor: OCT-2; motif: ATGMATATGCWAAT 0.0272962590382877 3691 100 32 0.32 0.00866973719859117
TF TF:M00453_1 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN; match class: 1 0.0273395572242257 332 27 4 0.148148148148148 0.0120481927710843
TF TF:M04327_1 Factor: GSX1; motif: NNYMATTANN; match class: 1 0.0273395572242257 5540 86 38 0.441860465116279 0.00685920577617329
TF TF:M04201 Factor: CEBPB; motif: ATTRCGCAAY 0.0273395572242257 4048 10 7 0.7 0.00172924901185771
TF TF:M00912 Factor: C/EBP; motif: NTTRCNNAANNN 0.0273395572242257 4968 117 45 0.384615384615385 0.00905797101449275
TF TF:M00776 Factor: SREBP; motif: VNNVTCACCCYA 0.0273395572242257 6530 44 25 0.568181818181818 0.00382848392036753
TF TF:M01866_1 Factor: C/EBPalpha; motif: NNNTTNNGCAANN; match class: 1 0.0277467554239008 933 141 16 0.113475177304965 0.0171489817792069
TF TF:M11738 Factor: COUP-TF1; motif: NRGGTCAAAGGTCRN 0.0277467554239008 2448 67 18 0.26865671641791 0.00735294117647059
TF TF:M01351_1 Factor: hoxa9; motif: NCGGYCATWAAAWTANW; match class: 1 0.0277467554239008 206 110 6 0.0545454545454545 0.029126213592233
TF TF:M00155 Factor: ARP-1; motif: TGARCCYTTGAMCCCW 0.0278891636099004 5581 12 9 0.75 0.00161261422684107
TF TF:M00456_1 Factor: FAC1; motif: NNNCAMAACACRNA; match class: 1 0.0279324860051359 2699 140 33 0.235714285714286 0.0122267506483883
TF TF:M00209 Factor: NF-Y; motif: NCTGATTGGYTASY 0.0281732174291943 3776 22 11 0.5 0.00291313559322034
TF TF:M11377 Factor: Spi-B; motif: NAAWGNGGAAGTN 0.0281732174291943 491 124 10 0.0806451612903226 0.0203665987780041
TF TF:M01255_1 Factor: ipf1; motif: RNWCATTAANWN; match class: 1 0.028724808717299 726 85 10 0.117647058823529 0.0137741046831956
TF TF:M11025 Factor: six4; motif: NCGTATCRNN 0.028724808717299 6586 35 21 0.6 0.00318858184026723
TF TF:M11037 Factor: Six-6; motif: NNSTATCRNN 0.0291152420953382 5270 70 31 0.442857142857143 0.00588235294117647
TF TF:M09924 Factor: c-Fos; motif: NTGAGTCAN 0.0291385851018631 2431 125 28 0.224 0.011517893870835
TF TF:M10698 Factor: HOXB5; motif: RTCRTTAN 0.0294123975374449 4697 134 48 0.358208955223881 0.0102192889078135
TF TF:M10609 Factor: Dlx-3; motif: NTCRTTAN 0.0294123975374449 4697 134 48 0.358208955223881 0.0102192889078135
TF TF:M09784 Factor: RELB; motif: NNATTCCCCNN 0.0294472788968326 5356 39 20 0.512820512820513 0.00373412994772218
TF TF:M04690 Factor: C/EBPbeta; motif: RTTGCGCAA 0.0295474311049137 3915 8 6 0.75 0.00153256704980843
TF TF:M11386 Factor: elf5; motif: AANNAGGAAGTR 0.0295474311049137 678 124 12 0.0967741935483871 0.0176991150442478
TF TF:M11317 Factor: C/EBPbeta; motif: NRTTGCGYAAYN 0.0296790069385219 4365 12 8 0.666666666666667 0.00183276059564719
TF TF:M10004 Factor: NF-kappaB2; motif: GGGRAANYCCC 0.0297590694910366 1073 59 10 0.169491525423729 0.00931966449207828
TF TF:M00205 Factor: GR; motif: GGTACAANNTGTYCTK 0.0297590694910366 6653 140 65 0.464285714285714 0.00977002855854502
TF TF:M11264_1 Factor: c-Jun; motif: NATGASTCATN; match class: 1 0.0297590694910366 4091 141 45 0.319148936170213 0.0109997555609875
TF TF:M11813 Factor: PPARdelta; motif: NRRGGTCATGACCYYT 0.0302595641742832 387 107 8 0.0747663551401869 0.020671834625323
TF TF:M04482 Factor: RARA; motif: ARRGGTCANSNGAGGTCA 0.0302595641742832 3852 129 40 0.310077519379845 0.0103842159916926
TF TF:M08888_1 Factor: MAFB; motif: NTCAGCN; match class: 1 0.0303098217053969 3375 137 38 0.277372262773723 0.0112592592592593
TF TF:M12355 Factor: ZNF549; motif: NTGCTKYCMW 0.0303098217053969 6708 107 52 0.485981308411215 0.00775193798449612
TF TF:M00086 Factor: Ik-1; motif: NHNTGGGAATRCC 0.0303098217053969 4427 43 19 0.441860465116279 0.00429184549356223
TF TF:M11775 Factor: RXR-alpha; motif: GRGGTCAAAGGTCAN 0.0303098217053969 5223 22 13 0.590909090909091 0.00248899100134023
TF TF:M02077 Factor: Spic; motif: NGNGGAASTN 0.030437575310638 8354 141 78 0.553191489361702 0.00933684462532918
TF TF:M02272 Factor: RXR:RAR; motif: RGKTCANNNRGAGGTCA 0.0312550933950287 8222 37 25 0.675675675675676 0.00304062271953296
TF TF:M09596 Factor: C/EBPalpha; motif: NRTTGTGCAAYNN 0.0312785556470539 5213 141 54 0.382978723404255 0.010358718588145
TF TF:M01866 Factor: C/EBPalpha; motif: NNNTTNNGCAANN 0.0313121983786989 5089 141 53 0.375886524822695 0.0104146197681273
TF TF:M03541 Factor: C-Jun; motif: TGACTC 0.0315933456802324 11287 60 46 0.766666666666667 0.00407548507132099
TF TF:M11268 Factor: JunD; motif: NATGASTCATS 0.03159805431596 2941 141 35 0.24822695035461 0.0119007140428426
TF TF:M04453_1 Factor: AR; motif: RGGWACAYNGTGTWCYN; match class: 1 0.0316414986985796 3794 68 24 0.352941176470588 0.00632577754348972
TF TF:M04168_1 Factor: CLOCK; motif: AACACGTGTN; match class: 1 0.0320564023099597 183 52 4 0.0769230769230769 0.0218579234972678
TF TF:M10639 Factor: Nkx2-3; motif: NSCACTTRNC 0.0321975141267312 867 12 4 0.333333333333333 0.00461361014994233
TF TF:M01185 Factor: BCL-6; motif: WRCTTTCKAGGRAT 0.0322125386644264 6054 78 37 0.474358974358974 0.00611166171126528
TF TF:M00953 Factor: AR; motif: NNNGNRRGNACANNGTGTTCTNNNNNN 0.0322127211960604 2415 38 12 0.315789473684211 0.00496894409937888
TF TF:M01654_1 Factor: DRI1; motif: AATTAA; match class: 1 0.0322845582374254 5831 136 57 0.419117647058824 0.00977533870691134
TF TF:M03546_1 Factor: Dlx-5; motif: AATTAN; match class: 1 0.0322845582374254 5831 136 57 0.419117647058824 0.00977533870691134
TF TF:M07323 Factor: IRF-4; motif: KRAAMNGAAANYN 0.0325144179913201 938 27 6 0.222222222222222 0.00639658848614072
TF TF:M09907_1 Factor: Erg; motif: NRRSAGGAAGNGG; match class: 1 0.0329411412295384 5070 142 53 0.373239436619718 0.0104536489151874
TF TF:M08817 Factor: HOXD13; motif: WNNAATAAWAY 0.0329655302465836 5669 94 41 0.436170212765957 0.00723231610513318
TF TF:M01801 Factor: ER-alpha; motif: AGGTCACNGTGACCT 0.0335824229760068 3396 106 31 0.292452830188679 0.0091283863368669
TF TF:M10701 Factor: HOXB5; motif: GTCATTAN 0.0335824229760068 5940 134 57 0.425373134328358 0.0095959595959596
TF TF:M01869 Factor: C/EBPgamma; motif: NRTKRSRMAAKN 0.0349472230565818 3194 122 33 0.270491803278689 0.0103318722604884
TF TF:M11265 Factor: c-Jun; motif: NATGACTCATN 0.0349472230565818 4632 141 49 0.347517730496454 0.0105785837651123
TF TF:M03826 Factor: HNF-1beta; motif: NNNYAAHCATTAACYN 0.0349472230565818 2830 90 24 0.266666666666667 0.00848056537102473
TF TF:M08904_1 Factor: TFIIB; motif: YTNTMTGMSN; match class: 1 0.0349472230565818 1445 142 21 0.147887323943662 0.0145328719723183
TF TF:M00912_1 Factor: C/EBP; motif: NTTRCNNAANNN; match class: 1 0.0349472230565818 892 139 15 0.107913669064748 0.0168161434977578
TF TF:M07284_1 Factor: Erg; motif: MCAGGAAA; match class: 1 0.0349472230565818 4412 133 45 0.338345864661654 0.0101994560290118
TF TF:M03581_1 Factor: TBP; motif: NGNNTATAAAA; match class: 1 0.035142431806665 1976 141 26 0.184397163120567 0.0131578947368421
TF TF:M00481_1 Factor: AR; motif: GGTACANNRTGTTCT; match class: 1 0.0358980146649364 2295 68 17 0.25 0.00740740740740741
TF TF:M10713 Factor: HOXD4; motif: RTCRTTAN 0.0358980146649364 3878 134 41 0.305970149253731 0.0105724600309438
TF TF:M00083 Factor: MZF-1; motif: NGNGGGGA 0.0359425301501099 2867 125 31 0.248 0.0108126961981165
TF TF:M11390 Factor: Erg; motif: NACAGGAARTN 0.0361670624192887 2772 140 33 0.235714285714286 0.0119047619047619
TF TF:M01212 Factor: STAT1:STAT1; motif: NTTTCCMGGAAAA 0.0361670624192887 103 97 4 0.0412371134020619 0.0388349514563107
TF TF:M11807 Factor: RAR-gamma; motif: RAGGTCATGACCTY 0.0364973981197042 2046 123 24 0.195121951219512 0.0117302052785924
TF TF:M09807 Factor: GATA2; motif: NNCTTATCTNN 0.0364973981197042 1347 94 15 0.159574468085106 0.0111358574610245
TF TF:M00339_1 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS; match class: 1 0.0364973981197042 1466 141 21 0.148936170212766 0.014324693042292
TF TF:M11431 Factor: PEA3; motif: NTCGTAAATGCA 0.0364973981197042 10559 18 16 0.888888888888889 0.00151529500899706
TF TF:M02014 Factor: HNF-3beta; motif: NTRTTTRYT 0.0364973981197042 2650 75 20 0.266666666666667 0.00754716981132075
TF TF:M02112_1 Factor: OC-2; motif: TCAATA; match class: 1 0.0367528937169996 2427 93 22 0.236559139784946 0.00906468891635764
TF TF:M02119_1 Factor: T3R-beta; motif: RRGNNANNNGAGGWCAN; match class: 1 0.037653781370877 486 36 5 0.138888888888889 0.0102880658436214
TF TF:M00422 Factor: FOXJ2; motif: NNNWAAAYAAAYANNNNN 0.037689872331252 2538 141 31 0.219858156028369 0.012214342001576
TF TF:M01808 Factor: NMYC; motif: CAYCTG 0.0377252193324087 12944 15 15 1 0.00115883807169345
TF TF:M01996_1 Factor: AR; motif: GNNCNNNNTGTTCTN; match class: 1 0.0377327008372951 294 86 6 0.0697674418604651 0.0204081632653061
TF TF:M10990 Factor: lmx1b; motif: NNNNTAATTAN 0.0378402776324518 1336 86 14 0.162790697674419 0.0104790419161677
TF TF:M08241_1 Factor: ERF:FOXO1A; motif: RTMAACAGGAARNS; match class: 1 0.0378402776324518 2010 140 26 0.185714285714286 0.0129353233830846
TF TF:M01419 Factor: Meis1; motif: WANNASCTGTCAAWNN 0.0378402776324518 1753 33 9 0.272727272727273 0.00513405590416429
TF TF:M03916 Factor: PRDM1; motif: NRAAAGTGAAAGTNN 0.0387412982658854 948 48 8 0.166666666666667 0.00843881856540084
TF TF:M01119 Factor: Kaiso; motif: NTCCTGCNAN 0.038829752383861 4264 8 6 0.75 0.00140712945590994
TF TF:M11676 Factor: IRF-3; motif: NGGAAANGGAAASNGAAACN 0.0388663371874021 562 137 11 0.0802919708029197 0.0195729537366548
TF TF:M03841_1 Factor: PEBP2beta; motif: TGTGGTY; match class: 1 0.0394267142389659 1963 30 9 0.3 0.00458481915435558
TF TF:M07391 Factor: NKX2B; motif: ANNCACTTNA 0.0394584716108951 2505 12 6 0.5 0.00239520958083832
TF TF:M04349 Factor: HOXB5; motif: NNYMATTANN 0.0395477003727221 5728 86 38 0.441860465116279 0.0066340782122905
TF TF:M04695 Factor: REST; motif: TTCAGCACCAYGGA 0.0395477003727221 1066 34 7 0.205882352941176 0.00656660412757974
TF TF:M08203 Factor: CDP:T-bet; motif: NTCACACNYYRATCRATM 0.0395477003727221 6147 142 61 0.429577464788732 0.00992353993818123
TF TF:M11032 Factor: Six-2; motif: NNGTAWCRNN 0.0395859286442986 10883 35 28 0.8 0.00257281999448681
TF TF:M04345 Factor: HOXB13; motif: CCAATAAAAN 0.0396020866727666 492 53 6 0.113207547169811 0.0121951219512195
TF TF:M01653_1 Factor: HMGIY; motif: NGWWATTN; match class: 1 0.0399459697323745 1496 140 21 0.15 0.0140374331550802
TF TF:M01172_1 Factor: PU.1; motif: NNNNYYYACTTCCTCTTTY; match class: 1 0.0403205338238695 580 134 11 0.082089552238806 0.0189655172413793
TF TF:M11683_1 Factor: IRF-8; motif: NCGAAACCGAAACYN; match class: 1 0.0403205338238695 814 33 6 0.181818181818182 0.00737100737100737
TF TF:M03559 Factor: Pit-1; motif: NNWWATTCAT 0.0403205338238695 5334 86 36 0.418604651162791 0.00674915635545557
TF TF:M09624 Factor: GATA-6; motif: NNNAGATAAGAWAN 0.0403205338238695 3203 13 7 0.538461538461538 0.00218545113955667
TF TF:M04519_1 Factor: E2F-4; motif: TTTGGCGCCAAA; match class: 1 0.0403205338238695 2547 33 11 0.333333333333333 0.00431880643894778
TF TF:M09953_1 Factor: HOXB13; motif: TTTTATNGSN; match class: 1 0.0403205338238695 79 134 4 0.0298507462686567 0.0506329113924051
TF TF:M11431_1 Factor: PEA3; motif: NTCGTAAATGCA; match class: 1 0.040563376969258 4298 94 33 0.351063829787234 0.00767798976268032
TF TF:M02026 Factor: MEF-2D; motif: WAAATAR 0.0406938109462728 7637 12 10 0.833333333333333 0.00130941469163284
TF TF:M00188 Factor: AP-1; motif: RGTGACTMANN 0.0407114460626647 3122 70 21 0.3 0.00672645739910314
TF TF:M04338 Factor: HNF1B; motif: NRTTAATNATTAACN 0.0409616376381757 508 70 7 0.1 0.0137795275590551
TF TF:M04632 Factor: SREBP-1; motif: NNNGTGGGGTGAN 0.0409616376381757 4860 110 41 0.372727272727273 0.00843621399176955
TF TF:M03819_1 Factor: Elk-1; motif: GGAAGN; match class: 1 0.0409616376381757 7491 90 48 0.533333333333333 0.00640768922707249
TF TF:M11740 Factor: COUP-TF1; motif: NRGGTCAAAGGTCAN 0.0409616376381757 898 21 5 0.238095238095238 0.00556792873051225
TF TF:M11566_1 Factor: HNF-3alpha; motif: NWRWGTMAAYAW; match class: 1 0.0412424026125225 517 69 7 0.101449275362319 0.0135396518375242
TF TF:M07457_1 Factor: Hoxa9; motif: NTTAAWTAMA; match class: 1 0.0415302672988983 1662 119 20 0.168067226890756 0.0120336943441637
TF TF:M03810 Factor: RXR:PXR; motif: NNNTGAMCTYNNNTGAMCYN 0.0415554489390917 1360 35 8 0.228571428571429 0.00588235294117647
TF TF:M08375 Factor: meis1:Prrxl1; motif: TGACANTAATTN 0.0415554489390917 1800 33 9 0.272727272727273 0.005
TF TF:M10058_1 Factor: Six-2; motif: KGAAAYNTGAKMC; match class: 1 0.0417095798964599 75 68 3 0.0441176470588235 0.04
TF TF:M11445 Factor: Elf-1; motif: NANCAGGAAGTR 0.0423578022459104 1689 134 22 0.164179104477612 0.0130254588513914
TF TF:M07433_1 Factor: TCF-1; motif: NNNSWWCAAAGN; match class: 1 0.0424417375899146 1094 11 4 0.363636363636364 0.0036563071297989
TF TF:M11684_1 Factor: IRF-8; motif: NYGAAACYGAAACTN; match class: 1 0.0430602696173096 832 33 6 0.181818181818182 0.00721153846153846
TF TF:M02100 Factor: MyoD; motif: CASCTGNCN 0.0430602696173096 616 92 9 0.0978260869565217 0.0146103896103896
TF TF:M01658_1 Factor: AML1; motif: TGTGGTK; match class: 1 0.0430830112847046 625 30 5 0.166666666666667 0.008
TF TF:M10634 Factor: Nkx2-3; motif: NSCACTTNNC 0.0436782198690216 2644 37 12 0.324324324324324 0.00453857791225416
TF TF:M08304_1 Factor: FOXO1A:ETV7; motif: NWMAACAGGAMNNNCTTCCNN; match class: 1 0.0436782198690216 7620 21 15 0.714285714285714 0.00196850393700787
TF TF:M10002_1 Factor: NF-1C; motif: NYTGGCNNYNNGCCARN; match class: 1 0.043779374533766 1693 126 21 0.166666666666667 0.0124040165386887
TF TF:M00770_1 Factor: C/EBP; motif: NNNTKNNGNAAN; match class: 1 0.043779374533766 1205 141 18 0.127659574468085 0.0149377593360996
TF TF:M11429 Factor: PEA3; motif: ACAGGAAGGAAGTN 0.043779374533766 5444 11 8 0.727272727272727 0.0014695077149155
TF TF:M09940 Factor: GATA-6; motif: NNAGATAAGANAA 0.0441715563640638 2856 8 5 0.625 0.00175070028011204
TF TF:M08888 Factor: MAFB; motif: NTCAGCN 0.0441808860004022 10140 102 67 0.656862745098039 0.00660749506903353
TF TF:M09667 Factor: TEF-3; motif: RCATTCCWGNNNN 0.0441808860004022 1034 19 5 0.263157894736842 0.00483558994197292
TF TF:M09726 Factor: GATAD2A; motif: CCTKTG 0.0441808860004022 15191 32 31 0.96875 0.00204068198275295
TF TF:M00746_1 Factor: Elf-1; motif: RNWMBAGGAART; match class: 1 0.0441808860004022 355 130 8 0.0615384615384615 0.0225352112676056
TF TF:M08676 Factor: C/EBPgamma:Elf-1; motif: TKRCGHAATWSCGGAAGT 0.0441808860004022 8605 16 13 0.8125 0.00151074956420686
TF TF:M11264 Factor: c-Jun; motif: NATGASTCATN 0.0441808860004022 4600 141 48 0.340425531914894 0.0104347826086957
TF TF:M00128 Factor: GATA-1; motif: NNCWGATARNNNN 0.0441808860004022 2516 81 20 0.246913580246914 0.00794912559618442
TF TF:M07466 Factor: Six-1; motif: CTCARRTTWCN 0.0452198451464423 3412 136 37 0.272058823529412 0.0108440797186401
TF TF:M10167 Factor: ZNF18; motif: GGTGTGAACNNN 0.0460846517114088 195 28 3 0.107142857142857 0.0153846153846154
TF TF:M08774 Factor: HOXD4; motif: NNYMATTANN 0.0464752188293469 4001 14 8 0.571428571428571 0.00199950012496876
TF TF:M01308 Factor: Sox-4; motif: AACAAWGR 0.0472061480797553 1653 73 14 0.191780821917808 0.00846944948578342
TF TF:M11570 Factor: HNF-3alpha; motif: CNYTAAGTAAACAAAN 0.0476287791607942 3651 141 40 0.283687943262411 0.0109559024924678
TF TF:M12295 Factor: ZNF282; motif: NTTCCCAYAACMCN 0.0476287791607942 668 87 9 0.103448275862069 0.0134730538922156
TF TF:M10843 Factor: HOXD13; motif: NSYAATAAAAN 0.0480727384352184 968 61 9 0.147540983606557 0.00929752066115703
TF TF:M08765 Factor: GATA-1; motif: NGATAAN 0.0480727384352184 3421 16 8 0.5 0.00233849751534639
TF TF:M00789 Factor: GATA; motif: WGATARN 0.0480727384352184 3421 16 8 0.5 0.00233849751534639
TF TF:M03216 Factor: GATA-6; motif: AGATAAN 0.0480727384352184 3421 16 8 0.5 0.00233849751534639
TF TF:M07214 Factor: GATA3; motif: AGATAAGA 0.0480727384352184 3417 16 8 0.5 0.00234123500146327
TF TF:M07254_1 Factor: Foxc1; motif: TTVYTTTNW; match class: 1 0.0480727384352184 2610 141 31 0.219858156028369 0.0118773946360153
TF TF:M11324 Factor: C/EBPgamma; motif: NNTTGCGYMANN 0.0484584014413047 2980 18 8 0.444444444444444 0.00268456375838926
TF TF:M00339 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS 0.0484584014413047 6806 141 65 0.460992907801418 0.00955039670878637
TF TF:M08957_1 Factor: NURR1:RXR-ALPHA; motif: NRGGTCRTTGACCYN; match class: 1 0.0484584014413047 3226 65 20 0.307692307692308 0.00619962802231866
TF TF:M08586 Factor: GCMb:Dlx-2; motif: ATRNGGGNNNNNTAATTR 0.0484584014413047 352 134 8 0.0597014925373134 0.0227272727272727
TF TF:M01269_1 Factor: NURR1; motif: YRRCCTT; match class: 1 0.0486143913264842 1166 11 4 0.363636363636364 0.00343053173241852
TF TF:M00999 Factor: AIRE; motif: WTNNNWNNTGGWWNNNWNGGNNWNWN 0.0486143913264842 3389 13 7 0.538461538461538 0.002065506048982
TF TF:M09947 Factor: HNF-4alpha; motif: NRGKNCAAAGTCCA 0.0486143913264842 2111 35 10 0.285714285714286 0.00473709142586452
TF TF:M04818 Factor: IRF-4; motif: RGGAASWGR 0.0487029731541972 9372 66 43 0.651515151515151 0.00458813486982501
TF TF:M09975_1 Factor: LEF-1; motif: NCCTTTSWNNTNYN; match class: 1 0.0487029731541972 542 11 3 0.272727272727273 0.00553505535055351
TF TF:M01255 Factor: ipf1; motif: RNWCATTAANWN 0.0487029731541972 3962 135 41 0.303703703703704 0.0103483089348814
TF TF:M04168 Factor: CLOCK; motif: AACACGTGTN 0.0487381525474922 225 52 4 0.0769230769230769 0.0177777777777778
TF TF:M01471 Factor: Lhx3; motif: NNAATTAATTAAWWNNN 0.0487381525474922 981 84 11 0.130952380952381 0.0112130479102956
TF TF:M11317_1 Factor: C/EBPbeta; motif: NRTTGCGYAAYN; match class: 1 0.0487552472596802 1314 10 4 0.4 0.0030441400304414
TF TF:M10126 Factor: ZNF134; motif: GCCTNNNCTMATCAGKTGAAGG 0.0487552472596802 223 86 5 0.0581395348837209 0.0224215246636771
TF TF:M07252_1 Factor: Elk-1; motif: CTTCCKG; match class: 1 0.0487552472596802 3644 116 34 0.293103448275862 0.00933040614709111
TF TF:M07103 Factor: JunB; motif: NRRTGASTCAK 0.0487552472596802 2383 123 26 0.211382113821138 0.0109106168694922
TF TF:M00447 Factor: AR; motif: AGWACATNWTGTTCT 0.0487552472596802 4183 69 25 0.36231884057971 0.0059765718383935
TF TF:M04903 Factor: HNF-4alpha; motif: AGTCCAAR 0.0487552472596802 6987 31 19 0.612903225806452 0.0027193359095463
TF TF:M04323 Factor: GBX2; motif: TAATTGNNCAATTA 0.0487552472596802 192 61 4 0.0655737704918033 0.0208333333333333
TF TF:M01385 Factor: Pax-4; motif: WNNNYTAATTARYNSNN 0.0487552472596802 3297 86 25 0.290697674418605 0.00758265089475281
TF TF:M01207_1 Factor: c-Ets-2; motif: CTTCCTG; match class: 1 0.0487552472596802 3644 116 34 0.293103448275862 0.00933040614709111
TF TF:M02027_1 Factor: PARP; motif: TTTCYN; match class: 1 0.048912492170903 12156 12 12 1 0.000987166831194472
TF TF:M08461_1 Factor: Erm:EVX1; motif: NNCGGAAATKR; match class: 1 0.0497402664347108 370 16 3 0.1875 0.00810810810810811
WP WP:WP2328 Allograft Rejection 1.62390833399475e-18 88 93 20 0.21505376344086 0.227272727272727
WP WP:WP4217 Ebola Virus Pathway on Host 2.93951710321361e-09 130 22 9 0.409090909090909 0.0692307692307692
WP WP:WP545 Complement Activation 1.09363589567308e-05 22 96 6 0.0625 0.272727272727273
WP WP:WP3937 Microglia Pathogen Phagocytosis Pathway 3.59825073472557e-05 40 106 7 0.0660377358490566 0.175
WP WP:WP2806 Human Complement System 3.59825073472557e-05 99 108 10 0.0925925925925926 0.101010101010101
WP WP:WP4884 Pathogenesis of SARS-CoV-2 Mediated by nsp9-nsp10 Complex 3.61519024630867e-05 21 139 6 0.0431654676258993 0.285714285714286
WP WP:WP3945 TYROBP Causal Network 3.8765418473612e-05 63 139 9 0.0647482014388489 0.142857142857143
WP WP:WP558 Complement and Coagulation Cascades 0.000153422748085816 59 96 7 0.0729166666666667 0.11864406779661
WP WP:WP5039 SARS-CoV-2 Innate Immunity Evasion and Cell-specific immune response 0.00107967177249812 68 116 7 0.0603448275862069 0.102941176470588
WP WP:WP1533 Vitamin B12 Metabolism 0.00192446383412231 53 116 6 0.0517241379310345 0.113207547169811
WP WP:WP4494 Selective expression of chemokine receptors during T-cell polarization 0.00196800085903963 29 139 5 0.0359712230215827 0.172413793103448
WP WP:WP75 Toll-like Receptor Signaling Pathway 0.00202340734353702 104 116 8 0.0689655172413793 0.0769230769230769
WP WP:WP3929 Chemokine signaling pathway 0.00213699660596366 165 116 10 0.0862068965517241 0.0606060606060606
WP WP:WP619 Type II interferon signaling (IFNG) 0.00326689828882157 37 126 5 0.0396825396825397 0.135135135135135
WP WP:WP183 Proteasome Degradation 0.0106208206889525 64 25 3 0.12 0.046875
WP WP:WP465 Tryptophan metabolism 0.0127947989187383 42 44 3 0.0681818181818182 0.0714285714285714
WP WP:WP1449 Regulation of toll-like receptor signaling pathway 0.0127947989187383 145 116 8 0.0689655172413793 0.0551724137931034
WP WP:WP15 Selenium Micronutrient Network 0.0127947989187383 91 44 4 0.0909090909090909 0.043956043956044
WP WP:WP3941 Oxidative Damage 0.0127947989187383 41 96 4 0.0416666666666667 0.0975609756097561
WP WP:WP4493 Cells and Molecules involved in local acute inflammatory response 0.0127947989187383 17 106 3 0.0283018867924528 0.176470588235294
WP WP:WP4462 Platelet-mediated interactions with vascular and circulating cells 0.0135634258021794 17 116 3 0.0258620689655172 0.176470588235294
WP WP:WP2431 Spinal Cord Injury 0.0221236232310142 118 97 6 0.0618556701030928 0.0508474576271186
WP WP:WP4585 Cancer immunotherapy by PD-1 blockade 0.0231997159953293 23 110 3 0.0272727272727273 0.130434782608696
WP WP:WP4329 miRNAs involvement in the immune response in sepsis 0.0361737744796563 63 50 3 0.06 0.0476190476190476

pEpi34 transcription factor target enrichment of top program genes

TF enrichment of pEpi34
Possible regulators of activation of pEpi34 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.