pEpiTp22 program activity among Epithelial cells

Activation of pEpiTp22
pEpiTp22 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpiTp22 by different cell subtypes
pEpiTp22 gene program activation among cells of different subtypes (Epithelial cells).

pEpiTp22 top program genes

Top genes of pEpiTp22 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpiTp22 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpiTp22
pEpiTp22 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0030029 actin filament-based process 2.53834882838829e-09 808 23 13 0.565217391304348 0.0160891089108911
GO:BP GO:0030036 actin cytoskeleton organization 6.77975915036215e-09 709 23 12 0.521739130434783 0.0169252468265162
GO:BP GO:0097435 supramolecular fiber organization 6.77975915036215e-09 734 28 13 0.464285714285714 0.0177111716621253
GO:BP GO:0007010 cytoskeleton organization 4.44268238108628e-08 1423 23 14 0.608695652173913 0.00983836964160225
GO:BP GO:0110053 regulation of actin filament organization 3.5306804685262e-07 284 23 8 0.347826086956522 0.028169014084507
GO:BP GO:0007015 actin filament organization 4.0261990655995e-07 445 23 9 0.391304347826087 0.0202247191011236
GO:BP GO:0032956 regulation of actin cytoskeleton organization 1.8459069143452e-06 366 23 8 0.347826086956522 0.0218579234972678
GO:BP GO:1902903 regulation of supramolecular fiber organization 2.49497312515633e-06 387 23 8 0.347826086956522 0.020671834625323
GO:BP GO:0032970 regulation of actin filament-based process 3.21921023862232e-06 406 23 8 0.347826086956522 0.0197044334975369
GO:BP GO:0031032 actomyosin structure organization 1.83642128838422e-05 199 23 6 0.260869565217391 0.0301507537688442
GO:BP GO:0008154 actin polymerization or depolymerization 1.83642128838422e-05 223 21 6 0.285714285714286 0.0269058295964126
GO:BP GO:0051493 regulation of cytoskeleton organization 1.91315912679495e-05 531 23 8 0.347826086956522 0.0150659133709981
GO:BP GO:0033043 regulation of organelle organization 8.49685501854991e-05 1203 23 10 0.434782608695652 0.00831255195344971
GO:BP GO:0030837 negative regulation of actin filament polymerization 9.8785989868302e-05 68 21 4 0.19047619047619 0.0588235294117647
GO:BP GO:0030833 regulation of actin filament polymerization 0.000134292857581141 177 21 5 0.238095238095238 0.0282485875706215
GO:BP GO:0070527 platelet aggregation 0.000141459696622992 64 25 4 0.16 0.0625
GO:BP GO:0008064 regulation of actin polymerization or depolymerization 0.00015058798633032 193 21 5 0.238095238095238 0.0259067357512953
GO:BP GO:0032272 negative regulation of protein polymerization 0.00015058798633032 82 21 4 0.19047619047619 0.0487804878048781
GO:BP GO:0006996 organelle organization 0.00015058798633032 4104 23 16 0.695652173913043 0.00389863547758285
GO:BP GO:0051098 regulation of binding 0.00015058798633032 365 6 4 0.666666666666667 0.010958904109589
GO:BP GO:0030832 regulation of actin filament length 0.00015058798633032 194 21 5 0.238095238095238 0.0257731958762887
GO:BP GO:0030041 actin filament polymerization 0.000151163819664925 196 21 5 0.238095238095238 0.0255102040816327
GO:BP GO:0051492 regulation of stress fiber assembly 0.000317046588905826 94 23 4 0.173913043478261 0.0425531914893617
GO:BP GO:0032271 regulation of protein polymerization 0.000317046588905826 236 21 5 0.238095238095238 0.0211864406779661
GO:BP GO:0034109 homotypic cell-cell adhesion 0.000317046588905826 87 25 4 0.16 0.0459770114942529
GO:BP GO:0050878 regulation of body fluid levels 0.000399880458652694 514 28 7 0.25 0.0136186770428016
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.000399880458652694 460 21 6 0.285714285714286 0.0130434782608696
GO:BP GO:0043149 stress fiber assembly 0.000399880458652694 109 23 4 0.173913043478261 0.036697247706422
GO:BP GO:0030038 contractile actin filament bundle assembly 0.000399880458652694 109 23 4 0.173913043478261 0.036697247706422
GO:BP GO:0032231 regulation of actin filament bundle assembly 0.000399880458652694 106 23 4 0.173913043478261 0.0377358490566038
GO:BP GO:0110020 regulation of actomyosin structure organization 0.000399880458652694 104 23 4 0.173913043478261 0.0384615384615385
GO:BP GO:0048870 cell motility 0.000607548074732056 1828 30 12 0.4 0.00656455142231947
GO:BP GO:0051674 localization of cell 0.000607548074732056 1828 30 12 0.4 0.00656455142231947
GO:BP GO:0030335 positive regulation of cell migration 0.000616724734294955 567 28 7 0.25 0.0123456790123457
GO:BP GO:0019221 cytokine-mediated signaling pathway 0.000616724734294955 810 14 6 0.428571428571429 0.00740740740740741
GO:BP GO:0044087 regulation of cellular component biogenesis 0.000616724734294955 990 23 8 0.347826086956522 0.00808080808080808
GO:BP GO:0045214 sarcomere organization 0.000616724734294955 41 23 3 0.130434782608696 0.0731707317073171
GO:BP GO:0060429 epithelium development 0.000616724734294955 1325 23 9 0.391304347826087 0.00679245283018868
GO:BP GO:0009653 anatomical structure morphogenesis 0.000618216102771196 2797 13 9 0.692307692307692 0.00321773328566321
GO:BP GO:0051258 protein polymerization 0.00066306957139219 305 21 5 0.238095238095238 0.0163934426229508
GO:BP GO:0031333 negative regulation of protein-containing complex assembly 0.000679081716838231 147 21 4 0.19047619047619 0.0272108843537415
GO:BP GO:0032535 regulation of cellular component size 0.000696497385190916 388 28 6 0.214285714285714 0.0154639175257732
GO:BP GO:2000147 positive regulation of cell motility 0.000717845088481358 591 28 7 0.25 0.011844331641286
GO:BP GO:0072659 protein localization to plasma membrane 0.000743028631207534 283 12 4 0.333333333333333 0.0141342756183746
GO:BP GO:0051272 positive regulation of cellular component movement 0.000773367952029131 604 28 7 0.25 0.0115894039735099
GO:BP GO:0009888 tissue development 0.000773367952029131 2107 24 11 0.458333333333333 0.00522069292833412
GO:BP GO:0044403 biological process involved in symbiotic interaction 0.000773367952029131 1001 18 7 0.388888888888889 0.00699300699300699
GO:BP GO:0040017 positive regulation of locomotion 0.000773367952029131 606 28 7 0.25 0.0115511551155116
GO:BP GO:0006928 movement of cell or subcellular component 0.000833373093002889 2311 30 13 0.433333333333333 0.0056252704456945
GO:BP GO:0051494 negative regulation of cytoskeleton organization 0.000885099810474411 166 21 4 0.19047619047619 0.0240963855421687
GO:BP GO:1902904 negative regulation of supramolecular fiber organization 0.000926704980812987 170 21 4 0.19047619047619 0.0235294117647059
GO:BP GO:0032233 positive regulation of actin filament bundle assembly 0.000926704980812987 64 19 3 0.157894736842105 0.046875
GO:BP GO:0016032 viral process 0.000938119080445851 942 14 6 0.428571428571429 0.00636942675159236
GO:BP GO:0016192 vesicle-mediated transport 0.000959135092757309 2180 28 12 0.428571428571429 0.0055045871559633
GO:BP GO:0040011 locomotion 0.00102333436793683 2028 30 12 0.4 0.00591715976331361
GO:BP GO:0051017 actin filament bundle assembly 0.00102333436793683 161 23 4 0.173913043478261 0.0248447204968944
GO:BP GO:0071345 cellular response to cytokine stimulus 0.00102815947143029 1132 23 8 0.347826086956522 0.00706713780918728
GO:BP GO:0070268 cornification 0.00103032373956295 112 12 3 0.25 0.0267857142857143
GO:BP GO:0061572 actin filament bundle organization 0.00104616733505687 164 23 4 0.173913043478261 0.024390243902439
GO:BP GO:1990778 protein localization to cell periphery 0.00107571885764016 338 12 4 0.333333333333333 0.0118343195266272
GO:BP GO:0022607 cellular component assembly 0.00112576334571633 3010 11 8 0.727272727272727 0.0026578073089701
GO:BP GO:0030168 platelet activation 0.00116214139284876 160 25 4 0.16 0.025
GO:BP GO:0030239 myofibril assembly 0.00116214139284876 62 23 3 0.130434782608696 0.0483870967741935
GO:BP GO:0010638 positive regulation of organelle organization 0.00116214139284876 603 22 6 0.272727272727273 0.00995024875621891
GO:BP GO:0051128 regulation of cellular component organization 0.00117162571978237 2412 23 11 0.478260869565217 0.00456053067993367
GO:BP GO:1902905 positive regulation of supramolecular fiber organization 0.00138968432560877 214 20 4 0.2 0.0186915887850467
GO:BP GO:0042060 wound healing 0.00140523732073425 549 25 6 0.24 0.0109289617486339
GO:BP GO:0034097 response to cytokine 0.00142326915568741 1226 23 8 0.347826086956522 0.0065252854812398
GO:BP GO:0007596 blood coagulation 0.00158127681610968 347 25 5 0.2 0.0144092219020173
GO:BP GO:0030334 regulation of cell migration 0.00158127681610968 999 28 8 0.285714285714286 0.00800800800800801
GO:BP GO:0050817 coagulation 0.0016041498794786 354 25 5 0.2 0.0141242937853107
GO:BP GO:0051495 positive regulation of cytoskeleton organization 0.0016041498794786 231 20 4 0.2 0.0173160173160173
GO:BP GO:0007599 hemostasis 0.0016041498794786 351 25 5 0.2 0.0142450142450142
GO:BP GO:0007155 cell adhesion 0.0016041498794786 1492 25 9 0.36 0.00603217158176944
GO:BP GO:0022610 biological adhesion 0.0016041498794786 1499 25 9 0.36 0.00600400266844563
GO:BP GO:0044085 cellular component biogenesis 0.0016041498794786 3257 11 8 0.727272727272727 0.00245624808105619
GO:BP GO:0051702 biological process involved in interaction with symbiont 0.00163040659191393 96 18 3 0.166666666666667 0.03125
GO:BP GO:0048468 cell development 0.00164053568619716 2100 6 5 0.833333333333333 0.00238095238095238
GO:BP GO:0090066 regulation of anatomical structure size 0.00166249560139559 518 28 6 0.214285714285714 0.0115830115830116
GO:BP GO:0031424 keratinization 0.00194426703508483 224 22 4 0.181818181818182 0.0178571428571429
GO:BP GO:0007166 cell surface receptor signaling pathway 0.0019840944122745 3210 14 9 0.642857142857143 0.00280373831775701
GO:BP GO:2000145 regulation of cell motility 0.00199222011945005 1061 28 8 0.285714285714286 0.00754005655042413
GO:BP GO:0032989 cellular component morphogenesis 0.00202974033509816 791 13 5 0.384615384615385 0.00632111251580278
GO:BP GO:0098609 cell-cell adhesion 0.00204346272613538 894 25 7 0.28 0.00782997762863535
GO:BP GO:0010634 positive regulation of epithelial cell migration 0.00216371187036499 181 28 4 0.142857142857143 0.0220994475138122
GO:BP GO:0048013 ephrin receptor signaling pathway 0.00237101643155105 88 23 3 0.130434782608696 0.0340909090909091
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 0.00242840809016132 177 12 3 0.25 0.0169491525423729
GO:BP GO:0040012 regulation of locomotion 0.00244783277216624 1104 28 8 0.285714285714286 0.0072463768115942
GO:BP GO:0051270 regulation of cellular component movement 0.00304175605145353 1141 28 8 0.285714285714286 0.007011393514461
GO:BP GO:0009611 response to wounding 0.00312794910214215 674 25 6 0.24 0.00890207715133531
GO:BP GO:0034613 cellular protein localization 0.003241044649787 2014 7 5 0.714285714285714 0.00248262164846077
GO:BP GO:0051641 cellular localization 0.003241044649787 3541 28 14 0.5 0.00395368539960463
GO:BP GO:0065008 regulation of biological quality 0.003241044649787 4131 25 14 0.56 0.00338900992495764
GO:BP GO:0010033 response to organic substance 0.003241044649787 3412 26 13 0.5 0.00381008206330598
GO:BP GO:0016043 cellular component organization 0.003241044649787 6566 23 17 0.739130434782609 0.00258909533962839
GO:BP GO:0010927 cellular component assembly involved in morphogenesis 0.003241044649787 107 23 3 0.130434782608696 0.0280373831775701
GO:BP GO:0070727 cellular macromolecule localization 0.003241044649787 2024 7 5 0.714285714285714 0.0024703557312253
GO:BP GO:0010631 epithelial cell migration 0.003241044649787 370 30 5 0.166666666666667 0.0135135135135135
GO:BP GO:0051099 positive regulation of binding 0.003241044649787 174 14 3 0.214285714285714 0.0172413793103448
GO:BP GO:0032501 multicellular organismal process 0.003241044649787 7946 30 23 0.766666666666667 0.00289453813239366
GO:BP GO:0090132 epithelium migration 0.00324572860580111 373 30 5 0.166666666666667 0.0134048257372654
GO:BP GO:0006887 exocytosis 0.00333189228065085 904 28 7 0.25 0.00774336283185841
GO:BP GO:0055002 striated muscle cell development 0.00336345472051749 111 23 3 0.130434782608696 0.027027027027027
GO:BP GO:0090130 tissue migration 0.00336345472051749 379 30 5 0.166666666666667 0.0131926121372032
GO:BP GO:0071310 cellular response to organic substance 0.0035331317591975 2776 24 11 0.458333333333333 0.00396253602305476
GO:BP GO:0032502 developmental process 0.00361085555879362 6628 29 20 0.689655172413793 0.00301750150875075
GO:BP GO:0071840 cellular component organization or biogenesis 0.00361085555879362 6760 23 17 0.739130434782609 0.00251479289940828
GO:BP GO:0030216 keratinocyte differentiation 0.00401528783797692 304 22 4 0.181818181818182 0.0131578947368421
GO:BP GO:0072657 protein localization to membrane 0.00401856271218634 665 28 6 0.214285714285714 0.00902255639097744
GO:BP GO:0048856 anatomical structure development 0.00403548881948603 6106 29 19 0.655172413793103 0.00311169341631182
GO:BP GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 0.00511511399410508 135 23 3 0.130434782608696 0.0222222222222222
GO:BP GO:0032879 regulation of localization 0.00511511399410508 2872 28 12 0.428571428571429 0.00417827298050139
GO:BP GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 0.00511511399410508 135 23 3 0.130434782608696 0.0222222222222222
GO:BP GO:0000904 cell morphogenesis involved in differentiation 0.00511511399410508 749 5 3 0.6 0.00400534045393859
GO:BP GO:0038094 Fc-gamma receptor signaling pathway 0.0051194170652847 137 23 3 0.130434782608696 0.0218978102189781
GO:BP GO:1902414 protein localization to cell junction 0.00524402505534394 113 28 3 0.107142857142857 0.0265486725663717
GO:BP GO:0010639 negative regulation of organelle organization 0.00529730051963593 361 21 4 0.19047619047619 0.0110803324099723
GO:BP GO:0045055 regulated exocytosis 0.00529730051963593 785 26 6 0.230769230769231 0.00764331210191083
GO:BP GO:0007165 signal transduction 0.00531125331841086 6309 23 16 0.695652173913043 0.00253605959740054
GO:BP GO:0002431 Fc receptor mediated stimulatory signaling pathway 0.00535203755470114 141 23 3 0.130434782608696 0.0212765957446809
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.00603541743662584 1042 28 7 0.25 0.00671785028790787
GO:BP GO:0001775 cell activation 0.00613520073746047 1495 26 8 0.307692307692308 0.00535117056856187
GO:BP GO:0055085 transmembrane transport 0.00613520073746047 1635 6 4 0.666666666666667 0.00244648318042813
GO:BP GO:0007043 cell-cell junction assembly 0.00632024261678611 151 23 3 0.130434782608696 0.0198675496688742
GO:BP GO:0009913 epidermal cell differentiation 0.00632024261678611 365 22 4 0.181818181818182 0.010958904109589
GO:BP GO:0001738 morphogenesis of a polarized epithelium 0.00637336356567891 152 23 3 0.130434782608696 0.0197368421052632
GO:BP GO:0071356 cellular response to tumor necrosis factor 0.00652304203097944 306 12 3 0.25 0.00980392156862745
GO:BP GO:0016477 cell migration 0.00695543290819064 1649 30 9 0.3 0.00545785324439054
GO:BP GO:0043270 positive regulation of ion transport 0.00695543290819064 694 6 3 0.5 0.00432276657060519
GO:BP GO:0061024 membrane organization 0.00727480546048719 973 23 6 0.260869565217391 0.00616649537512847
GO:BP GO:0051179 localization 0.00774752885045789 6901 24 17 0.708333333333333 0.0024634110998406
GO:BP GO:0034612 response to tumor necrosis factor 0.00781857846906794 331 12 3 0.25 0.00906344410876133
GO:BP GO:0010632 regulation of epithelial cell migration 0.00784713559492576 306 28 4 0.142857142857143 0.0130718954248366
GO:BP GO:0001667 ameboidal-type cell migration 0.00788142744193482 494 30 5 0.166666666666667 0.0101214574898785
GO:BP GO:0099173 postsynapse organization 0.00806224580483275 169 23 3 0.130434782608696 0.0177514792899408
GO:BP GO:0008104 protein localization 0.0084823744847488 2770 7 5 0.714285714285714 0.00180505415162455
GO:BP GO:0030855 epithelial cell differentiation 0.00894662806429116 798 29 6 0.206896551724138 0.0075187969924812
GO:BP GO:0051716 cellular response to stimulus 0.0091359707342755 7781 24 18 0.75 0.00231332733581802
GO:BP GO:0051130 positive regulation of cellular component organization 0.00931203066063839 1153 28 7 0.25 0.00607111882046834
GO:BP GO:0043588 skin development 0.00944617133091431 424 22 4 0.181818181818182 0.00943396226415094
GO:BP GO:0048518 positive regulation of biological process 0.00946300757497528 6363 28 18 0.642857142857143 0.00282885431400283
GO:BP GO:0055001 muscle cell development 0.00946300757497528 184 23 3 0.130434782608696 0.016304347826087
GO:BP GO:0000902 cell morphogenesis 0.0101307438921927 1037 5 3 0.6 0.00289296046287367
GO:BP GO:0048731 system development 0.0103853454537303 5052 29 16 0.551724137931034 0.00316706254948535
GO:BP GO:0034330 cell junction organization 0.0106067928664415 722 23 5 0.217391304347826 0.00692520775623269
GO:BP GO:0023052 signaling 0.01074269568546 6810 23 16 0.695652173913043 0.00234948604992658
GO:BP GO:0007154 cell communication 0.0110207552141403 6829 23 16 0.695652173913043 0.0023429491872895
GO:BP GO:0002252 immune effector process 0.0111491536175034 1309 26 7 0.269230769230769 0.0053475935828877
GO:BP GO:0051649 establishment of localization in cell 0.0113935895933585 2813 28 11 0.392857142857143 0.00391041592605759
GO:BP GO:0006909 phagocytosis 0.0117085755896958 387 26 4 0.153846153846154 0.0103359173126615
GO:BP GO:0070887 cellular response to chemical stimulus 0.0120147483838628 3393 24 11 0.458333333333333 0.00324196875921014
GO:BP GO:0051234 establishment of localization 0.0120499485250432 5372 28 16 0.571428571428571 0.00297840655249442
GO:BP GO:0030154 cell differentiation 0.0121159782710054 4350 17 10 0.588235294117647 0.00229885057471264
GO:BP GO:0050896 response to stimulus 0.0123515986245744 9407 26 21 0.807692307692308 0.00223238014244711
GO:BP GO:0051050 positive regulation of transport 0.012366987233379 923 6 3 0.5 0.00325027085590466
GO:BP GO:0008544 epidermis development 0.012366987233379 475 22 4 0.181818181818182 0.00842105263157895
GO:BP GO:0006950 response to stress 0.0124935521089038 4170 26 13 0.5 0.00311750599520384
GO:BP GO:0045216 cell-cell junction organization 0.0129530210584538 216 23 3 0.130434782608696 0.0138888888888889
GO:BP GO:0048869 cellular developmental process 0.0132829799488248 4428 17 10 0.588235294117647 0.0022583559168925
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.0132872878886726 540 20 4 0.2 0.00740740740740741
GO:BP GO:0042221 response to chemical 0.0134247973733979 4781 26 14 0.538461538461538 0.00292825768667643
GO:BP GO:0033036 macromolecule localization 0.0135703268949957 3218 7 5 0.714285714285714 0.00155376009944065
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.0141089308502496 263 20 3 0.15 0.0114068441064639
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 0.014524209225676 2255 26 9 0.346153846153846 0.00399113082039911
GO:BP GO:0038093 Fc receptor signaling pathway 0.0152394727896608 238 23 3 0.130434782608696 0.0126050420168067
GO:BP GO:0061061 muscle structure development 0.0152394727896608 645 29 5 0.172413793103448 0.00775193798449612
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0155814926904556 253 22 3 0.136363636363636 0.0118577075098814
GO:BP GO:0051094 positive regulation of developmental process 0.0160862483801101 1341 28 7 0.25 0.0052199850857569
GO:BP GO:0006955 immune response 0.0161016994163349 2311 26 9 0.346153846153846 0.00389441800086543
GO:BP GO:1905475 regulation of protein localization to membrane 0.016106650263605 201 28 3 0.107142857142857 0.0149253731343284
GO:BP GO:0022604 regulation of cell morphogenesis 0.0169200778284228 309 19 3 0.157894736842105 0.00970873786407767
GO:BP GO:0032940 secretion by cell 0.0169450828172945 1364 28 7 0.25 0.00513196480938416
GO:BP GO:0010466 negative regulation of peptidase activity 0.0169917771746437 267 22 3 0.136363636363636 0.0112359550561798
GO:BP GO:0051336 regulation of hydrolase activity 0.0171316958229071 1321 22 6 0.272727272727273 0.00454201362604088
GO:BP GO:0099003 vesicle-mediated transport in synapse 0.0172828881083619 210 28 3 0.107142857142857 0.0142857142857143
GO:BP GO:0050793 regulation of developmental process 0.0173182188501299 2605 28 10 0.357142857142857 0.00383877159309021
GO:BP GO:0048513 animal organ development 0.0176966730363418 3672 12 7 0.583333333333333 0.00190631808278867
GO:BP GO:0050790 regulation of catalytic activity 0.0186863303775669 2545 6 4 0.666666666666667 0.00157170923379175
GO:BP GO:0043312 neutrophil degranulation 0.0187030529346952 482 26 4 0.153846153846154 0.00829875518672199
GO:BP GO:0002283 neutrophil activation involved in immune response 0.0190041624506987 485 26 4 0.153846153846154 0.00824742268041237
GO:BP GO:0140352 export from cell 0.0192684236166728 1418 28 7 0.25 0.00493653032440056
GO:BP GO:0002009 morphogenesis of an epithelium 0.0196791885652998 560 23 4 0.173913043478261 0.00714285714285714
GO:BP GO:0007275 multicellular organism development 0.0198260429688161 5613 13 9 0.692307692307692 0.00160342063067878
GO:BP GO:0043933 protein-containing complex subunit organization 0.0198260429688161 1963 21 7 0.333333333333333 0.00356597045338767
GO:BP GO:0006810 transport 0.0198533852074295 5224 28 15 0.535714285714286 0.00287136294027565
GO:BP GO:0002446 neutrophil mediated immunity 0.019885376308855 497 26 4 0.153846153846154 0.00804828973843058
GO:BP GO:0044092 negative regulation of molecular function 0.0199124556806961 1219 6 3 0.5 0.00246103363412633
GO:BP GO:0042119 neutrophil activation 0.0199124556806961 498 26 4 0.153846153846154 0.00803212851405622
GO:BP GO:0036230 granulocyte activation 0.0205362654538596 504 26 4 0.153846153846154 0.00793650793650794
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.0208367705354028 1455 28 7 0.25 0.00481099656357388
GO:BP GO:0051146 striated muscle cell differentiation 0.0208448399799028 289 23 3 0.130434782608696 0.0103806228373702
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 0.0223570240325476 1202 26 6 0.230769230769231 0.00499168053244592
GO:BP GO:0046903 secretion 0.0237600218956513 1501 28 7 0.25 0.00466355762824783
GO:BP GO:0043299 leukocyte degranulation 0.0239633512610474 535 26 4 0.153846153846154 0.00747663551401869
GO:BP GO:0002275 myeloid cell activation involved in immune response 0.0254811025062246 547 26 4 0.153846153846154 0.00731261425959781
GO:BP GO:0043269 regulation of ion transport 0.0258357807500631 1379 6 3 0.5 0.00217548948513416
GO:BP GO:0002444 myeloid leukocyte mediated immunity 0.0259294363527863 551 26 4 0.153846153846154 0.00725952813067151
GO:BP GO:0034622 cellular protein-containing complex assembly 0.0262162046333237 1107 21 5 0.238095238095238 0.004516711833785
GO:BP GO:0044093 positive regulation of molecular function 0.0263255128400918 1771 19 6 0.315789473684211 0.00338791643139469
GO:BP GO:0034220 ion transmembrane transport 0.0263255128400918 1397 6 3 0.5 0.00214745884037223
GO:BP GO:0046034 ATP metabolic process 0.0270248729830215 314 24 3 0.125 0.00955414012738853
GO:BP GO:0051239 regulation of multicellular organismal process 0.0271346984868975 2861 28 10 0.357142857142857 0.0034952813701503
GO:BP GO:0048667 cell morphogenesis involved in neuron differentiation 0.0273205753880186 602 13 3 0.230769230769231 0.00498338870431894
GO:BP GO:0048871 multicellular organismal homeostasis 0.0283154195232911 530 28 4 0.142857142857143 0.00754716981132075
GO:BP GO:0050794 regulation of cellular process 0.0283912822358098 11473 24 21 0.875 0.00183038438071995
GO:BP GO:0045861 negative regulation of proteolysis 0.0293501452977796 359 22 3 0.136363636363636 0.00835654596100279
GO:BP GO:0048729 tissue morphogenesis 0.029751350813844 667 23 4 0.173913043478261 0.00599700149925037
GO:BP GO:0065009 regulation of molecular function 0.0301257637359391 3221 22 9 0.409090909090909 0.00279416330332195
GO:BP GO:0051129 negative regulation of cellular component organization 0.0301257637359391 759 11 3 0.272727272727273 0.00395256916996047
GO:BP GO:0065003 protein-containing complex assembly 0.0315846201390835 1680 21 6 0.285714285714286 0.00357142857142857
GO:BP GO:0048812 neuron projection morphogenesis 0.0327751253553575 664 13 3 0.230769230769231 0.00451807228915663
GO:BP GO:0001525 angiogenesis 0.0333194253242363 617 26 4 0.153846153846154 0.00648298217179903
GO:BP GO:0120039 plasma membrane bounded cell projection morphogenesis 0.0340638940727473 678 13 3 0.230769230769231 0.00442477876106195
GO:BP GO:0048858 cell projection morphogenesis 0.034379949921783 682 13 3 0.230769230769231 0.00439882697947214
GO:BP GO:0043542 endothelial cell migration 0.0355525490395146 290 30 3 0.1 0.0103448275862069
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.0358050197235887 1645 6 3 0.5 0.00182370820668693
GO:BP GO:0019220 regulation of phosphate metabolic process 0.0358050197235887 1645 6 3 0.5 0.00182370820668693
GO:BP GO:0032990 cell part morphogenesis 0.0360284586284443 699 13 3 0.230769230769231 0.00429184549356223
GO:BP GO:0042692 muscle cell differentiation 0.0373118251925217 390 23 3 0.130434782608696 0.00769230769230769
GO:BP GO:0006936 muscle contraction 0.0386352401557731 364 25 3 0.12 0.00824175824175824
GO:BP GO:0002274 myeloid leukocyte activation 0.0408690467423084 667 26 4 0.153846153846154 0.00599700149925037
GO:BP GO:0052548 regulation of endopeptidase activity 0.0431269131183907 437 22 3 0.136363636363636 0.0068649885583524
GO:BP GO:0051049 regulation of transport 0.0437557099248121 1809 6 3 0.5 0.00165837479270315
GO:BP GO:0010628 positive regulation of gene expression 0.0447200383035988 1160 24 5 0.208333333333333 0.00431034482758621
GO:BP GO:0050808 synapse organization 0.0447200383035988 428 23 3 0.130434782608696 0.00700934579439252
GO:BP GO:0090150 establishment of protein localization to membrane 0.044816865048182 351 28 3 0.107142857142857 0.00854700854700855
GO:BP GO:0009150 purine ribonucleotide metabolic process 0.0451326435035112 414 24 3 0.125 0.0072463768115942
GO:BP GO:0009605 response to external stimulus 0.0463990839075434 2944 26 9 0.346153846153846 0.0030570652173913
GO:BP GO:0006811 ion transport 0.046531318879648 3661 6 4 0.666666666666667 0.00109259765091505
GO:BP GO:0048514 blood vessel morphogenesis 0.0466872127353918 711 26 4 0.153846153846154 0.00562587904360056
GO:BP GO:0012501 programmed cell death 0.0472351538904475 2143 24 7 0.291666666666667 0.00326644890340644
GO:BP GO:0002366 leukocyte activation involved in immune response 0.0475161101280425 717 26 4 0.153846153846154 0.00557880055788006
GO:BP GO:0052547 regulation of peptidase activity 0.0475161101280425 467 22 3 0.136363636363636 0.00642398286937901
GO:BP GO:0002263 cell activation involved in immune response 0.0479515332163296 721 26 4 0.153846153846154 0.00554785020804438
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0479515332163296 470 22 3 0.136363636363636 0.00638297872340425
GO:BP GO:0009259 ribonucleotide metabolic process 0.0482650273458606 431 24 3 0.125 0.00696055684454756
GO:CC GO:0043230 extracellular organelle 1.34806486443585e-18 2263 28 25 0.892857142857143 0.0110472823685373
GO:CC GO:0070062 extracellular exosome 1.34806486443585e-18 2176 28 25 0.892857142857143 0.0114889705882353
GO:CC GO:1903561 extracellular vesicle 1.34806486443585e-18 2261 28 25 0.892857142857143 0.0110570544007077
GO:CC GO:0005615 extracellular space 2.34015270095482e-15 3594 28 26 0.928571428571429 0.00723427935447969
GO:CC GO:0005576 extracellular region 1.97417763155309e-14 4567 28 27 0.964285714285714 0.00591197722793957
GO:CC GO:0031982 vesicle 3.42875704331113e-14 4055 28 26 0.928571428571429 0.00641183723797781
GO:CC GO:0005856 cytoskeleton 6.09835144958951e-08 2332 25 16 0.64 0.00686106346483705
GO:CC GO:0015629 actin cytoskeleton 3.00731255913687e-07 513 25 9 0.36 0.0175438596491228
GO:CC GO:0005829 cytosol 2.27479879662331e-06 5303 25 20 0.8 0.00377145012257213
GO:CC GO:0031252 cell leading edge 4.96789394888966e-06 422 21 7 0.333333333333333 0.0165876777251185
GO:CC GO:0070161 anchoring junction 5.62218414802587e-06 836 23 9 0.391304347826087 0.0107655502392345
GO:CC GO:0005938 cell cortex 7.73472639581859e-06 311 19 6 0.315789473684211 0.0192926045016077
GO:CC GO:0001726 ruffle 2.17950838822757e-05 179 21 5 0.238095238095238 0.0279329608938547
GO:CC GO:0005737 cytoplasm 2.19777224955014e-05 11911 29 29 1 0.00243472420451683
GO:CC GO:0005912 adherens junction 4.67563124119351e-05 173 12 4 0.333333333333333 0.023121387283237
GO:CC GO:0005911 cell-cell junction 0.000112610005120777 494 12 5 0.416666666666667 0.0101214574898785
GO:CC GO:0019897 extrinsic component of plasma membrane 0.000204580702494863 176 6 3 0.5 0.0170454545454545
GO:CC GO:0072562 blood microparticle 0.000257324750527858 140 23 4 0.173913043478261 0.0285714285714286
GO:CC GO:0120025 plasma membrane bounded cell projection 0.000364277546793811 2229 28 12 0.428571428571429 0.0053835800807537
GO:CC GO:0043228 non-membrane-bounded organelle 0.000377173887780501 5346 25 17 0.68 0.00317994762439207
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.000377173887780501 5338 25 17 0.68 0.00318471337579618
GO:CC GO:0042383 sarcolemma 0.000388588840597704 140 10 3 0.3 0.0214285714285714
GO:CC GO:0042995 cell projection 0.00041718196113934 2330 28 12 0.428571428571429 0.00515021459227468
GO:CC GO:0016459 myosin complex 0.000429541037328047 57 25 3 0.12 0.0526315789473684
GO:CC GO:0030027 lamellipodium 0.000452452910766529 200 21 4 0.19047619047619 0.02
GO:CC GO:0019898 extrinsic component of membrane 0.000603804861032205 313 6 3 0.5 0.00958466453674121
GO:CC GO:0099513 polymeric cytoskeletal fiber 0.000646214940929246 764 28 7 0.25 0.00916230366492147
GO:CC GO:0005925 focal adhesion 0.000836843662537126 420 23 5 0.217391304347826 0.0119047619047619
GO:CC GO:0030055 cell-substrate junction 0.000879792812790949 427 23 5 0.217391304347826 0.0117096018735363
GO:CC GO:0030054 cell junction 0.00121030315856624 2105 13 7 0.538461538461538 0.00332541567695962
GO:CC GO:0062023 collagen-containing extracellular matrix 0.00126753395985699 421 6 3 0.5 0.00712589073634204
GO:CC GO:0098685 Schaffer collateral - CA1 synapse 0.00131215778175644 80 28 3 0.107142857142857 0.0375
GO:CC GO:0034774 secretory granule lumen 0.00142526899721108 320 8 3 0.375 0.009375
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.00143698204507499 324 8 3 0.375 0.00925925925925926
GO:CC GO:0031983 vesicle lumen 0.00143698204507499 326 8 3 0.375 0.00920245398773006
GO:CC GO:0005882 intermediate filament 0.00162260818226802 218 12 3 0.25 0.0137614678899083
GO:CC GO:0005884 actin filament 0.00197437249765091 118 23 3 0.130434782608696 0.0254237288135593
GO:CC GO:0048471 perinuclear region of cytoplasm 0.00232561167198573 735 18 5 0.277777777777778 0.00680272108843537
GO:CC GO:0030312 external encapsulating structure 0.00232561167198573 563 6 3 0.5 0.00532859680284192
GO:CC GO:0099081 supramolecular polymer 0.00232561167198573 1001 28 7 0.25 0.00699300699300699
GO:CC GO:0045111 intermediate filament cytoskeleton 0.00232561167198573 259 12 3 0.25 0.0115830115830116
GO:CC GO:0099512 supramolecular fiber 0.00232561167198573 993 28 7 0.25 0.00704934541792548
GO:CC GO:0031012 extracellular matrix 0.00232561167198573 562 6 3 0.5 0.00533807829181495
GO:CC GO:0098862 cluster of actin-based cell projections 0.00241956606058604 162 19 3 0.157894736842105 0.0185185185185185
GO:CC GO:0005622 intracellular anatomical structure 0.00315754986225042 14790 29 29 1 0.00196078431372549
GO:CC GO:0045335 phagocytic vesicle 0.00421933965478983 137 28 3 0.107142857142857 0.0218978102189781
GO:CC GO:0032991 protein-containing complex 0.00498340195320398 5548 25 15 0.6 0.00270367700072098
GO:CC GO:0071944 cell periphery 0.00525154489172321 6169 19 13 0.684210526315789 0.00210731074728481
GO:CC GO:0043227 membrane-bounded organelle 0.00650104505012454 12858 28 26 0.928571428571429 0.00202208741639446
GO:CC GO:0043226 organelle 0.00750206898721082 14008 28 27 0.964285714285714 0.00192747001713307
GO:CC GO:0099080 supramolecular complex 0.00773300961249993 1323 28 7 0.25 0.00529100529100529
GO:CC GO:0030424 axon 0.00773300961249993 660 28 5 0.178571428571429 0.00757575757575758
GO:CC GO:0030016 myofibril 0.00779085059860057 231 23 3 0.130434782608696 0.012987012987013
GO:CC GO:0043229 intracellular organelle 0.00806247460925084 12491 25 23 0.92 0.00184132575454327
GO:CC GO:0043292 contractile fiber 0.00836982625455328 240 23 3 0.130434782608696 0.0125
GO:CC GO:0030141 secretory granule 0.0110795914722817 851 8 3 0.375 0.00352526439482961
GO:CC GO:0150034 distal axon 0.013955861838934 308 23 3 0.130434782608696 0.00974025974025974
GO:CC GO:0098590 plasma membrane region 0.0145969124485412 1240 19 5 0.263157894736842 0.00403225806451613
GO:CC GO:0097708 intracellular vesicle 0.0145969124485412 2428 28 9 0.321428571428571 0.00370675453047776
GO:CC GO:0031410 cytoplasmic vesicle 0.0145969124485412 2424 28 9 0.321428571428571 0.00371287128712871
GO:CC GO:0099503 secretory vesicle 0.0156879675152336 1020 8 3 0.375 0.00294117647058824
GO:CC GO:0005634 nucleus 0.0164666248527008 7592 24 16 0.666666666666667 0.00210748155953635
GO:CC GO:0005635 nuclear envelope 0.0194566322107909 467 18 3 0.166666666666667 0.00642398286937901
GO:CC GO:0030139 endocytic vesicle 0.021027723471031 306 28 3 0.107142857142857 0.00980392156862745
GO:CC GO:0005886 plasma membrane 0.0212505801402553 5681 19 11 0.578947368421053 0.00193627882415068
GO:CC GO:0043005 neuron projection 0.0266997785514741 1380 28 6 0.214285714285714 0.00434782608695652
GO:CC GO:0012505 endomembrane system 0.0454544551176208 4640 8 5 0.625 0.00107758620689655
GO:MF GO:0045296 cadherin binding 3.14338374871356e-08 333 24 9 0.375 0.027027027027027
GO:MF GO:0048306 calcium-dependent protein binding 3.01947511315717e-07 82 30 6 0.2 0.0731707317073171
GO:MF GO:0008092 cytoskeletal protein binding 6.00504344241076e-07 996 29 12 0.413793103448276 0.0120481927710843
GO:MF GO:0050839 cell adhesion molecule binding 6.00504344241076e-07 546 24 9 0.375 0.0164835164835165
GO:MF GO:0044548 S100 protein binding 6.97015033605272e-07 14 8 3 0.375 0.214285714285714
GO:MF GO:0005509 calcium ion binding 3.19251235915209e-06 721 30 10 0.333333333333333 0.013869625520111
GO:MF GO:0098641 cadherin binding involved in cell-cell adhesion 4.37060510553922e-06 18 12 3 0.25 0.166666666666667
GO:MF GO:0003785 actin monomer binding 1.42243661908255e-05 30 11 3 0.272727272727273 0.1
GO:MF GO:0098632 cell-cell adhesion mediator activity 7.58962896502803e-05 49 12 3 0.25 0.0612244897959184
GO:MF GO:0003779 actin binding 8.01528360925662e-05 448 29 7 0.241379310344828 0.015625
GO:MF GO:0098631 cell adhesion mediator activity 0.000103660089667264 58 12 3 0.25 0.0517241379310345
GO:MF GO:0005200 structural constituent of cytoskeleton 0.00011479686457511 104 23 4 0.173913043478261 0.0384615384615385
GO:MF GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 0.00110686442993964 80 21 3 0.142857142857143 0.0375
GO:MF GO:0005198 structural molecule activity 0.00161312342779628 698 23 6 0.260869565217391 0.00859598853868195
GO:MF GO:1902936 phosphatidylinositol bisphosphate binding 0.00203041874138753 104 21 3 0.142857142857143 0.0288461538461538
GO:MF GO:0051015 actin filament binding 0.0024811743394625 212 29 4 0.137931034482759 0.0188679245283019
GO:MF GO:0044877 protein-containing complex binding 0.00413566317728161 1287 29 8 0.275862068965517 0.00621600621600622
GO:MF GO:0042802 identical protein binding 0.00450391902029083 2067 24 9 0.375 0.00435413642960813
GO:MF GO:0005515 protein binding 0.00536986136543074 14767 30 30 1 0.00203155684973251
GO:MF GO:1901981 phosphatidylinositol phosphate binding 0.0054217582992266 172 21 3 0.142857142857143 0.0174418604651163
GO:MF GO:0004857 enzyme inhibitor activity 0.0102391951307365 385 26 4 0.153846153846154 0.0103896103896104
GO:MF GO:0042803 protein homodimerization activity 0.0112917342067446 676 8 3 0.375 0.00443786982248521
GO:MF GO:0035091 phosphatidylinositol binding 0.0123521237419719 255 21 3 0.142857142857143 0.0117647058823529
GO:MF GO:0005543 phospholipid binding 0.014578852115548 454 26 4 0.153846153846154 0.00881057268722467
GO:MF GO:0046983 protein dimerization activity 0.0301427892594205 1069 8 3 0.375 0.00280636108512629
GO:MF GO:0043167 ion binding 0.0434083403027101 6057 30 16 0.533333333333333 0.00264157173518243
HPA HPA:0381191 placenta; cytotrophoblasts[≥Low] 0.00270926061680962 303 3 3 1 0.0099009900990099
HPA HPA:0291163 liver; cholangiocytes[High] 0.00270926061680962 294 12 5 0.416666666666667 0.0170068027210884
HPA HPA:0381192 placenta; cytotrophoblasts[≥Medium] 0.00270926061680962 272 3 3 1 0.0110294117647059
HPA HPA:0381211 placenta; syncytiotrophoblasts - cell body[≥Low] 0.00370656729281491 370 3 3 1 0.00810810810810811
KEGG KEGG:05132 Salmonella infection 1.91157036579481e-06 249 25 9 0.36 0.036144578313253
KEGG KEGG:04810 Regulation of actin cytoskeleton 5.50646639825518e-06 216 25 8 0.32 0.037037037037037
KEGG KEGG:04530 Tight junction 0.000209704172495072 169 25 6 0.24 0.0355029585798817
KEGG KEGG:05131 Shigellosis 0.00131271405285527 246 25 6 0.24 0.024390243902439
KEGG KEGG:04670 Leukocyte transendothelial migration 0.00478829568613214 114 25 4 0.16 0.0350877192982456
KEGG KEGG:04611 Platelet activation 0.00549289081560006 124 25 4 0.16 0.032258064516129
KEGG KEGG:05100 Bacterial invasion of epithelial cells 0.0115153397032987 77 23 3 0.130434782608696 0.038961038961039
KEGG KEGG:05130 Pathogenic Escherichia coli infection 0.0163629837038911 196 23 4 0.173913043478261 0.0204081632653061
KEGG KEGG:04510 Focal adhesion 0.0215138993850269 200 25 4 0.16 0.02
KEGG KEGG:05135 Yersinia infection 0.0337248427031265 136 23 3 0.130434782608696 0.0220588235294118
KEGG KEGG:04921 Oxytocin signaling pathway 0.0345324481498633 154 23 3 0.130434782608696 0.0194805194805195
KEGG KEGG:04015 Rap1 signaling pathway 0.0421833260138352 210 23 3 0.130434782608696 0.0142857142857143
KEGG KEGG:05164 Influenza A 0.0421833260138352 169 28 3 0.107142857142857 0.0177514792899408
KEGG KEGG:04360 Axon guidance 0.0421833260138352 181 25 3 0.12 0.0165745856353591
MIRNA MIRNA:hsa-miR-7150 hsa-miR-7150 0.000174913326684514 136 30 6 0.2 0.0441176470588235
MIRNA MIRNA:hsa-miR-1-3p hsa-miR-1-3p 0.00703565378761461 915 27 9 0.333333333333333 0.00983606557377049
MIRNA MIRNA:hsa-miR-5010-5p hsa-miR-5010-5p 0.0134267153655413 153 25 4 0.16 0.0261437908496732
MIRNA MIRNA:hsa-miR-4665-5p hsa-miR-4665-5p 0.0134267153655413 161 25 4 0.16 0.0248447204968944
MIRNA MIRNA:hsa-miR-4525 hsa-miR-4525 0.0134267153655413 152 25 4 0.16 0.0263157894736842
MIRNA MIRNA:hsa-miR-1275 hsa-miR-1275 0.0134267153655413 160 25 4 0.16 0.025
MIRNA MIRNA:hsa-miR-3179 hsa-miR-3179 0.0159566820222174 182 24 4 0.166666666666667 0.021978021978022
MIRNA MIRNA:hsa-miR-6780b-5p hsa-miR-6780b-5p 0.0235508553480059 232 24 4 0.166666666666667 0.0172413793103448
MIRNA MIRNA:hsa-miR-1914-3p hsa-miR-1914-3p 0.0235508553480059 141 20 3 0.15 0.0212765957446809
MIRNA MIRNA:hsa-miR-3176 hsa-miR-3176 0.0235508553480059 105 24 3 0.125 0.0285714285714286
MIRNA MIRNA:hsa-miR-320a hsa-miR-320a 0.0235508553480059 584 28 6 0.214285714285714 0.0102739726027397
MIRNA MIRNA:hsa-miR-4723-5p hsa-miR-4723-5p 0.0235508553480059 252 25 4 0.16 0.0158730158730159
MIRNA MIRNA:hsa-miR-4725-3p hsa-miR-4725-3p 0.0235508553480059 232 24 4 0.166666666666667 0.0172413793103448
MIRNA MIRNA:hsa-miR-486-3p hsa-miR-486-3p 0.0235508553480059 201 29 4 0.137931034482759 0.0199004975124378
MIRNA MIRNA:hsa-miR-4271 hsa-miR-4271 0.0235508553480059 236 24 4 0.166666666666667 0.0169491525423729
MIRNA MIRNA:hsa-miR-6738-5p hsa-miR-6738-5p 0.0235508553480059 134 20 3 0.15 0.0223880597014925
MIRNA MIRNA:hsa-miR-5194 hsa-miR-5194 0.0235508553480059 135 20 3 0.15 0.0222222222222222
MIRNA MIRNA:hsa-miR-625-5p hsa-miR-625-5p 0.0235508553480059 226 25 4 0.16 0.0176991150442478
MIRNA MIRNA:hsa-miR-6870-5p hsa-miR-6870-5p 0.0235508553480059 254 25 4 0.16 0.015748031496063
MIRNA MIRNA:hsa-miR-7111-5p hsa-miR-7111-5p 0.0235508553480059 257 25 4 0.16 0.0155642023346304
MIRNA MIRNA:hsa-miR-133a-3p hsa-miR-133a-3p 0.0279804453049036 129 24 3 0.125 0.0232558139534884
MIRNA MIRNA:hsa-miR-326 hsa-miR-326 0.0308703677014121 136 24 3 0.125 0.0220588235294118
MIRNA MIRNA:hsa-miR-1249-5p hsa-miR-1249-5p 0.0379731150599596 272 29 4 0.137931034482759 0.0147058823529412
MIRNA MIRNA:hsa-miR-6797-5p hsa-miR-6797-5p 0.0383280155094023 275 29 4 0.137931034482759 0.0145454545454545
MIRNA MIRNA:hsa-miR-769-3p hsa-miR-769-3p 0.0385513750578623 165 23 3 0.130434782608696 0.0181818181818182
MIRNA MIRNA:hsa-miR-4472 hsa-miR-4472 0.0391667790211663 177 24 3 0.125 0.0169491525423729
MIRNA MIRNA:hsa-miR-221-3p hsa-miR-221-3p 0.0391667790211663 366 24 4 0.166666666666667 0.0109289617486339
MIRNA MIRNA:hsa-miR-491-5p hsa-miR-491-5p 0.0391667790211663 171 24 3 0.125 0.0175438596491228
MIRNA MIRNA:hsa-miR-1207-5p hsa-miR-1207-5p 0.0391667790211663 287 30 4 0.133333333333333 0.0139372822299652
MIRNA MIRNA:hsa-miR-4447 hsa-miR-4447 0.0391667790211663 177 24 3 0.125 0.0169491525423729
MIRNA MIRNA:hsa-miR-4763-3p hsa-miR-4763-3p 0.0391667790211663 282 30 4 0.133333333333333 0.0141843971631206
MIRNA MIRNA:hsa-miR-34a-5p hsa-miR-34a-5p 0.0400569657502561 728 30 6 0.2 0.00824175824175824
MIRNA MIRNA:hsa-miR-222-3p hsa-miR-222-3p 0.0449726906357426 393 24 4 0.166666666666667 0.0101781170483461
MIRNA MIRNA:hsa-miR-4736 hsa-miR-4736 0.0463418696317671 171 30 3 0.1 0.0175438596491228
MIRNA MIRNA:hsa-miR-4534 hsa-miR-4534 0.0463418696317671 203 27 3 0.111111111111111 0.0147783251231527
MIRNA MIRNA:hsa-miR-423-5p hsa-miR-423-5p 0.0463418696317671 342 29 4 0.137931034482759 0.0116959064327485
MIRNA MIRNA:hsa-miR-1307-3p hsa-miR-1307-3p 0.0463418696317671 239 23 3 0.130434782608696 0.0125523012552301
MIRNA MIRNA:hsa-miR-96-5p hsa-miR-96-5p 0.0463418696317671 201 27 3 0.111111111111111 0.0149253731343284
MIRNA MIRNA:hsa-miR-6770-5p hsa-miR-6770-5p 0.0477961486955333 225 25 3 0.12 0.0133333333333333
MIRNA MIRNA:hsa-miR-6766-5p hsa-miR-6766-5p 0.0483352674437901 245 24 3 0.125 0.0122448979591837
MIRNA MIRNA:hsa-miR-6756-5p hsa-miR-6756-5p 0.0483352674437901 245 24 3 0.125 0.0122448979591837
MIRNA MIRNA:hsa-miR-744-5p hsa-miR-744-5p 0.0483352674437901 435 27 4 0.148148148148148 0.00919540229885057
MIRNA MIRNA:hsa-miR-218-5p hsa-miR-218-5p 0.0483352674437901 814 8 3 0.375 0.00368550368550369
MIRNA MIRNA:hsa-miR-92a-2-5p hsa-miR-92a-2-5p 0.0483352674437901 245 24 3 0.125 0.0122448979591837
MIRNA MIRNA:hsa-miR-4779 hsa-miR-4779 0.0498476007966309 286 22 3 0.136363636363636 0.0104895104895105
MIRNA MIRNA:hsa-miR-193b-3p hsa-miR-193b-3p 0.0498476007966309 847 23 5 0.217391304347826 0.00590318772136954
MIRNA MIRNA:hsa-miR-5698 hsa-miR-5698 0.0498476007966309 491 25 4 0.16 0.00814663951120163
REAC REAC:R-HSA-2682334 EPH-Ephrin signaling 1.61478505924095e-07 90 25 7 0.28 0.0777777777777778
REAC REAC:R-HSA-195258 RHO GTPase Effectors 2.73429715177495e-07 283 23 9 0.391304347826087 0.0318021201413428
REAC REAC:R-HSA-5627117 RHO GTPases Activate ROCKs 1.39693878968004e-06 19 19 4 0.210526315789474 0.210526315789474
REAC REAC:R-HSA-194315 Signaling by Rho GTPases 2.91588206096573e-06 413 23 9 0.391304347826087 0.0217917675544794
REAC REAC:R-HSA-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 2.91588206096573e-06 413 23 9 0.391304347826087 0.0217917675544794
REAC REAC:R-HSA-445355 Smooth Muscle Contraction 3.13716909463444e-05 38 25 4 0.16 0.105263157894737
REAC REAC:R-HSA-3928662 EPHB-mediated forward signaling 3.13716909463444e-05 40 23 4 0.173913043478261 0.1
REAC REAC:R-HSA-1266738 Developmental Biology 3.13716909463444e-05 1069 25 12 0.48 0.0112254443405051
REAC REAC:R-HSA-422475 Axon guidance 4.12614358392783e-05 549 25 9 0.36 0.0163934426229508
REAC REAC:R-HSA-9675108 Nervous system development 5.36583657556451e-05 574 25 9 0.36 0.0156794425087108
REAC REAC:R-HSA-373755 Semaphorin interactions 5.7449419570947e-05 64 19 4 0.210526315789474 0.0625
REAC REAC:R-HSA-5625900 RHO GTPases activate CIT 5.7449419570947e-05 19 19 3 0.157894736842105 0.157894736842105
REAC REAC:R-HSA-5625740 RHO GTPases activate PKNs 5.8425068792203e-05 58 22 4 0.181818181818182 0.0689655172413793
REAC REAC:R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 5.8425068792203e-05 20 19 3 0.157894736842105 0.15
REAC REAC:R-HSA-400685 Sema4D in semaphorin signaling 9.54528080174561e-05 24 19 3 0.157894736842105 0.125
REAC REAC:R-HSA-109582 Hemostasis 0.000133569466276012 657 15 7 0.466666666666667 0.0106544901065449
REAC REAC:R-HSA-114608 Platelet degranulation 0.000188446159090875 125 15 4 0.266666666666667 0.032
REAC REAC:R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 0.000208368764021913 130 15 4 0.266666666666667 0.0307692307692308
REAC REAC:R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 0.000264010359778638 72 28 4 0.142857142857143 0.0555555555555556
REAC REAC:R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 0.000394328194870981 35 23 3 0.130434782608696 0.0857142857142857
REAC REAC:R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 0.000695625324955624 116 23 4 0.173913043478261 0.0344827586206897
REAC REAC:R-HSA-5663220 RHO GTPases Activate Formins 0.00123082967851229 136 23 4 0.173913043478261 0.0294117647058824
REAC REAC:R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 0.00131860593736672 140 23 4 0.173913043478261 0.0285714285714286
REAC REAC:R-HSA-6809371 Formation of the cornified envelope 0.00191945972596843 128 12 3 0.25 0.0234375
REAC REAC:R-HSA-76002 Platelet activation, signaling and aggregation 0.00201555866188729 258 15 4 0.266666666666667 0.0155038759689922
REAC REAC:R-HSA-397014 Muscle contraction 0.00547247728819203 205 25 4 0.16 0.0195121951219512
REAC REAC:R-HSA-6805567 Keratinization 0.00651255830555719 215 12 3 0.25 0.013953488372093
REAC REAC:R-HSA-9664407 Parasite infection 0.00679829309331797 113 23 3 0.130434782608696 0.0265486725663717
REAC REAC:R-HSA-9664422 FCGR3A-mediated phagocytosis 0.00679829309331797 113 23 3 0.130434782608696 0.0265486725663717
REAC REAC:R-HSA-9664417 Leishmania phagocytosis 0.00679829309331797 113 23 3 0.130434782608696 0.0265486725663717
REAC REAC:R-HSA-8856828 Clathrin-mediated endocytosis 0.0105619086225237 144 23 3 0.130434782608696 0.0208333333333333
REAC REAC:R-HSA-168249 Innate Immune System 0.0182479297851767 1073 24 7 0.291666666666667 0.0065237651444548
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.0356990403303595 446 14 3 0.214285714285714 0.00672645739910314
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 0.0381244390887766 842 14 4 0.285714285714286 0.00475059382422803
REAC REAC:R-HSA-199991 Membrane Trafficking 0.0395312550231915 625 28 5 0.178571428571429 0.008
REAC REAC:R-HSA-9658195 Leishmania infection 0.0436427364361459 303 23 3 0.130434782608696 0.0099009900990099
TF TF:M09971 Factor: GKLF; motif: WGGGYGKGGC 4.55576742699491e-05 5546 25 21 0.84 0.00378651280201947
TF TF:M09971_1 Factor: GKLF; motif: WGGGYGKGGC; match class: 1 0.00160275368392331 1352 25 10 0.4 0.00739644970414201
TF TF:M09973_1 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN; match class: 1 0.00160275368392331 6607 29 22 0.758620689655172 0.00332980172544271
TF TF:M00634 Factor: GCM; motif: CNNRCCCGCATD 0.00160275368392331 2152 6 6 1 0.00278810408921933
TF TF:M09734_1 Factor: ZNF692; motif: SYNGGSCCCASCCNC; match class: 1 0.00160275368392331 6255 30 22 0.733333333333333 0.0035171862509992
TF TF:M09972 Factor: BTEB2; motif: WGGGTGKGGCNGGN 0.00160275368392331 9217 28 25 0.892857142857143 0.00271237929912119
TF TF:M01588 Factor: GKLF; motif: GCCMCRCCCNNN 0.00160275368392331 8944 29 26 0.896551724137931 0.00290697674418605
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.00160275368392331 12729 30 30 1 0.00235682300259251
TF TF:M12173 Factor: GKLF; motif: NNCCMCRCCCN 0.00160275368392331 10023 25 24 0.96 0.00239449266686621
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 0.00160275368392331 10494 25 24 0.96 0.00228702115494568
TF TF:M09729 Factor: LUMAN; motif: CYCAGCYYCY 0.00160275368392331 10686 30 28 0.933333333333333 0.00262025079543328
TF TF:M03876_1 Factor: Kaiso; motif: GCMGGGRGCRGS; match class: 1 0.00193242379570467 9106 30 26 0.866666666666667 0.00285526026795519
TF TF:M12351 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC 0.00273484751064855 12302 25 25 1 0.00203218988782312
TF TF:M12135_1 Factor: mbnl2; motif: NYGCYTYGCTTN; match class: 1 0.00344236694958931 1097 7 5 0.714285714285714 0.00455788514129444
TF TF:M11374 Factor: Spi-B; motif: NAWGRGGAAGTR 0.0038969713217575 2512 28 13 0.464285714285714 0.00517515923566879
TF TF:M09593 Factor: Bach1; motif: TGCTGAGTCANNS 0.0038969713217575 536 30 7 0.233333333333333 0.0130597014925373
TF TF:M01588_1 Factor: GKLF; motif: GCCMCRCCCNNN; match class: 1 0.00396621720213865 3962 25 15 0.6 0.00378596668349319
TF TF:M03876 Factor: Kaiso; motif: GCMGGGRGCRGS 0.00396621720213865 13622 30 30 1 0.0022023197768316
TF TF:M09871 Factor: bach2; motif: TGCTGAGTCAN 0.00546009154810784 395 18 5 0.277777777777778 0.0126582278481013
TF TF:M02076 Factor: Spi-B; motif: NGNGGAAGYN 0.00586073684812406 303 12 4 0.333333333333333 0.0132013201320132
TF TF:M00821 Factor: Nrf-2; motif: NTGCTGAGTCAKN 0.00595960718281656 4719 30 18 0.6 0.00381436745073109
TF TF:M00444_1 Factor: VDR; motif: GGGKNARNRRGGWSA; match class: 1 0.00658177212821973 4534 19 13 0.684210526315789 0.00286722540802823
TF TF:M09963 Factor: JunB; motif: NNTGAGTCANN 0.00658177212821973 905 15 6 0.4 0.00662983425414365
TF TF:M07610 Factor: Nrf2; motif: NTGCTGAGTCANN 0.00658177212821973 1012 5 4 0.8 0.00395256916996047
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.00797675880349139 14096 30 30 1 0.00212826333711691
TF TF:M02278 Factor: SPI1; motif: AGGAAGT 0.00930165437041956 6837 17 14 0.823529411764706 0.00204768173175369
TF TF:M09922_1 Factor: Fra-1; motif: NNNTGAGTCAYN; match class: 1 0.00930165437041956 677 30 7 0.233333333333333 0.0103397341211226
TF TF:M09916 Factor: Erm; motif: NRRSAGGAARNGRN 0.00930165437041956 6711 30 21 0.7 0.00312919088064372
TF TF:M07382 Factor: Fli-1; motif: MGGAAGT 0.00930165437041956 6837 17 14 0.823529411764706 0.00204768173175369
TF TF:M09903 Factor: elf5; motif: NNNANSAGGAAGTNN 0.00930165437041956 1243 24 8 0.333333333333333 0.00643604183427192
TF TF:M08874 Factor: E2F1; motif: NNNNNGCGSSAAAN 0.00930165437041956 7201 18 15 0.833333333333333 0.00208304402166366
TF TF:M09973 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN 0.00930165437041956 10853 29 26 0.896551724137931 0.00239565097208145
TF TF:M04595_1 Factor: SALL2; motif: GGGTGGG; match class: 1 0.00930165437041956 7373 30 22 0.733333333333333 0.0029838600298386
TF TF:M08875 Factor: E2F; motif: NNTTTCGCGCN 0.00930165437041956 6203 18 14 0.777777777777778 0.00225697243269386
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.00930165437041956 14106 29 29 1 0.00205586275343825
TF TF:M03579 Factor: PEA3; motif: AGGAAGT 0.00930165437041956 6837 17 14 0.823529411764706 0.00204768173175369
TF TF:M01870 Factor: C-ets-1; motif: AGGAAGN 0.00930165437041956 6837 17 14 0.823529411764706 0.00204768173175369
TF TF:M10071 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG 0.00930165437041956 8495 29 23 0.793103448275862 0.00270747498528546
TF TF:M00444 Factor: VDR; motif: GGGKNARNRRGGWSA 0.00938517730201858 10308 30 26 0.866666666666667 0.00252231276678308
TF TF:M11265 Factor: c-Jun; motif: NATGACTCATN 0.00940172795544505 4632 30 17 0.566666666666667 0.00367012089810017
TF TF:M00761_1 Factor: p53; motif: RGRCAWGNCY; match class: 1 0.00940172795544505 317 16 4 0.25 0.0126182965299685
TF TF:M07039_1 Factor: ETF; motif: CCCCGCCCCYN; match class: 1 0.00940172795544505 13611 25 25 1 0.00183674968775255
TF TF:M07461 Factor: KLF; motif: GGGNGGGG 0.00940172795544505 8757 15 14 0.933333333333333 0.00159872102318145
TF TF:M07103 Factor: JunB; motif: NRRTGASTCAK 0.00940172795544505 2383 30 12 0.4 0.00503566932438103
TF TF:M11415_1 Factor: GABP-alpha; motif: NRCCGGAAGTN; match class: 1 0.00940172795544505 546 28 6 0.214285714285714 0.010989010989011
TF TF:M01104 Factor: MOVO-B; motif: GNGGGGG 0.00940172795544505 10261 26 23 0.884615384615385 0.00224149693012377
TF TF:M00800 Factor: AP-2; motif: GSCCSCRGGCNRNRNN 0.00940172795544505 9119 16 15 0.9375 0.00164491720583397
TF TF:M09616_1 Factor: Fra-2; motif: RTGACTCANNN; match class: 1 0.00940172795544505 728 30 7 0.233333333333333 0.00961538461538462
TF TF:M09972_1 Factor: BTEB2; motif: WGGGTGKGGCNGGN; match class: 1 0.00956889141048576 3919 15 10 0.666666666666667 0.0025516713447308
TF TF:M00221 Factor: SREBP-1; motif: KATCACCCCAC 0.00968353084566169 7502 18 15 0.833333333333333 0.00199946680885097
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.0104134382047515 10281 29 25 0.862068965517241 0.00243167007100477
TF TF:M01203 Factor: SPI1; motif: NNAAWGNGGAASTNNNN 0.0104134382047515 2643 28 12 0.428571428571429 0.00454029511918275
TF TF:M09862 Factor: ZNF614; motif: NCYCWGCCYYNNN 0.0107315891330636 9361 12 12 1 0.00128191432539259
TF TF:M09893 Factor: E2F-3; motif: NNGGCGGGAAA 0.0109943237817133 6065 19 14 0.736842105263158 0.0023083264633141
TF TF:M07091 Factor: Fra-1; motif: RRTGASTCAKN 0.0109943237817133 1716 30 10 0.333333333333333 0.00582750582750583
TF TF:M07290_1 Factor: GLI; motif: NGACCMCCCAN; match class: 1 0.0109943237817133 1902 14 7 0.5 0.00368033648790747
TF TF:M11445 Factor: Elf-1; motif: NANCAGGAAGTR 0.0109943237817133 1689 25 9 0.36 0.00532859680284192
TF TF:M11387 Factor: elf5; motif: NNNNMGGAAGTN 0.0109943237817133 2598 21 10 0.476190476190476 0.00384911470361817
TF TF:M00470_1 Factor: AP-2gamma; motif: GCCYNNGGS; match class: 1 0.0110458786385885 5600 16 12 0.75 0.00214285714285714
TF TF:M00378_1 Factor: Pax-4; motif: NNNNNYCACCCB; match class: 1 0.011061226829666 14711 30 30 1 0.00203929032696622
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.0118984228078918 10419 29 25 0.862068965517241 0.00239946252039543
TF TF:M10530 Factor: sp4; motif: NNNGCYCCGCCCCCY 0.0136488742820992 8227 29 22 0.758620689655172 0.00267412179409262
TF TF:M07114 Factor: c-MAF:NF-E2p45; motif: ATGACTCAGCANWTN 0.0138507134686923 745 4 3 0.75 0.00402684563758389
TF TF:M00983 Factor: MAF; motif: NGCTGAGTCAN 0.013913018933246 6031 30 19 0.633333333333333 0.00315038965345714
TF TF:M12152 Factor: Sp1; motif: NWRGCCACGCCCMCN 0.014135023205996 7341 26 19 0.730769230769231 0.00258820324206511
TF TF:M09734 Factor: ZNF692; motif: SYNGGSCCCASCCNC 0.0146096760219389 11678 30 27 0.9 0.00231203973283096
TF TF:M11385_1 Factor: ESE-1; motif: NTGTGCGGATGCN; match class: 1 0.0148938104328531 5491 21 14 0.666666666666667 0.00254962666181023
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.0148938104328531 10357 28 24 0.857142857142857 0.00231727334170126
TF TF:M10681 Factor: HPX42B; motif: NNYNATTANN 0.0150144118525948 2469 4 4 1 0.00162008910490077
TF TF:M10002_1 Factor: NF-1C; motif: NYTGGCNNYNNGCCARN; match class: 1 0.0152466923431801 1693 5 4 0.8 0.00236266981689309
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.0165660565948249 14873 29 29 1 0.00194984199556243
TF TF:M12136 Factor: mbnl2; motif: NYGCYTYGCYTN 0.0166426837342697 5391 13 10 0.769230769230769 0.00185494342422556
TF TF:M12186 Factor: BTEB4; motif: NCCACGCCCM 0.0167540633394066 9135 29 23 0.793103448275862 0.00251778872468528
TF TF:M00749_1 Factor: SREBP-1; motif: CACSCCA; match class: 1 0.0167540633394066 2768 6 5 0.833333333333333 0.00180635838150289
TF TF:M04918 Factor: Egr-1; motif: ACCGCCC 0.0171033987343717 5608 30 18 0.6 0.00320970042796006
TF TF:M00428 Factor: E2F-1; motif: NKTSSCGC 0.0174543728585679 8947 20 17 0.85 0.0019000782385157
TF TF:M07261 Factor: LKLF; motif: GGGGTGGKSN 0.017586451477343 9774 19 17 0.894736842105263 0.00173930836914262
TF TF:M07277 Factor: BTEB2; motif: RGGGNGKGGN 0.0187934734204357 8492 29 22 0.758620689655172 0.00259067357512953
TF TF:M00925_1 Factor: AP-1; motif: NTGACTCAN; match class: 1 0.0189847107986558 224 30 4 0.133333333333333 0.0178571428571429
TF TF:M09631 Factor: JunB; motif: NNNTGAGTCAY 0.0189847107986558 1915 30 10 0.333333333333333 0.00522193211488251
TF TF:M11446 Factor: Elf-1; motif: RANSMGGAAGTR 0.0191131161250198 2915 21 10 0.476190476190476 0.00343053173241852
TF TF:M09969 Factor: EKLF; motif: NGGGYGKGGCNNGG 0.0216881019367245 4589 25 14 0.56 0.00305077358901721
TF TF:M04617 Factor: LRF; motif: NGNAGNGGGTYN 0.0216881019367245 6164 20 14 0.7 0.00227125243348475
TF TF:M09615_1 Factor: Fra-1; motif: NRTGACTCATN; match class: 1 0.021805759534339 559 6 3 0.5 0.00536672629695885
TF TF:M04685 Factor: NF-E2; motif: RTGACTCAG 0.021805759534339 312 23 4 0.173913043478261 0.0128205128205128
TF TF:M03920 Factor: SP1; motif: RCCMCRCCCMC 0.0222513434299245 7283 29 20 0.689655172413793 0.00274612110394068
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.0222513434299245 15260 30 30 1 0.00196592398427261
TF TF:M10073 Factor: PU.1; motif: NRAAAGAGGAAGTGRNN 0.0222513434299245 2416 21 9 0.428571428571429 0.00372516556291391
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.0222513434299245 15268 30 30 1 0.00196489389572963
TF TF:M00924 Factor: AP-1; motif: TGACTCANNSKN 0.0224382603711804 2801 30 12 0.4 0.00428418421992146
TF TF:M00800_1 Factor: AP-2; motif: GSCCSCRGGCNRNRNN; match class: 1 0.0226256695642451 4268 24 13 0.541666666666667 0.00304592314901593
TF TF:M02280_1 Factor: AP1; motif: TGACTCA; match class: 1 0.0226256695642451 599 6 3 0.5 0.00500834724540901
TF TF:M07461_1 Factor: KLF; motif: GGGNGGGG; match class: 1 0.0226256695642451 3397 29 13 0.448275862068966 0.00382690609361201
TF TF:M09918_1 Factor: Pet-1; motif: GCNGGAAGYG; match class: 1 0.0226256695642451 7159 20 15 0.75 0.00209526470177399
TF TF:M12315 Factor: ZF5; motif: RTGCGCGTGCACGYGN 0.0226256695642451 184 17 3 0.176470588235294 0.016304347826087
TF TF:M03551_1 Factor: JunB; motif: TGACTCAN; match class: 1 0.0226256695642451 599 6 3 0.5 0.00500834724540901
TF TF:M01858 Factor: AP-2beta; motif: GCNNNGGSCNGVGGGN 0.0226256695642451 7418 25 18 0.72 0.00242653006201132
TF TF:M01007 Factor: SRF; motif: CNKNKCCTTATWTGGNNNN 0.0226256695642451 256 29 4 0.137931034482759 0.015625
TF TF:M11375 Factor: Spi-B; motif: NAWGCGGAAGTN 0.0226256695642451 2608 28 11 0.392857142857143 0.00421779141104294
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 0.0226256695642451 14575 25 25 1 0.00171526586620926
TF TF:M07409 Factor: BTEB2; motif: GCCCCRCCCH 0.0230436643491479 5198 14 10 0.714285714285714 0.00192381685263563
TF TF:M10056_1 Factor: DRRS; motif: GNNGGGWGGG; match class: 1 0.0230436643491479 980 30 7 0.233333333333333 0.00714285714285714
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.023183119229416 10233 29 24 0.827586206896552 0.00234535326883612
TF TF:M09923_1 Factor: Fra-2; motif: NNRTGAGTCAYN; match class: 1 0.0232586604517758 614 6 3 0.5 0.00488599348534202
TF TF:M00446_1 Factor: Spz1; motif: DNNGGRGGGWWNNNN; match class: 1 0.0233436960491051 2858 30 12 0.4 0.00419874037788663
TF TF:M07379 Factor: c-Ets-2; motif: NNCTTCCTNNN 0.0234960005016283 3487 16 9 0.5625 0.00258101519931173
TF TF:M11297_1 Factor: jdp2; motif: NRTGASTCAYN; match class: 1 0.0243013988134048 1667 30 9 0.3 0.00539892021595681
TF TF:M00470 Factor: AP-2gamma; motif: GCCYNNGGS 0.0244588168187736 9422 20 17 0.85 0.00180428783697729
TF TF:M08941_1 Factor: C-JUN:FRA-2; motif: NRTGACGTMAT; match class: 1 0.0244588168187736 3353 30 13 0.433333333333333 0.00387712496271995
TF TF:M02075 Factor: PDEF; motif: MCCGGATNTN 0.0244588168187736 2666 24 10 0.416666666666667 0.00375093773443361
TF TF:M11419_1 Factor: ER81; motif: NNCCGGAWGYN; match class: 1 0.0244588168187736 1427 28 8 0.285714285714286 0.00560616678346181
TF TF:M03815 Factor: c-Fos; motif: TGACTCAN 0.0244588168187736 2455 30 11 0.366666666666667 0.0044806517311609
TF TF:M00655 Factor: PEA3; motif: ACWTCCK 0.0244588168187736 9452 17 15 0.882352941176471 0.00158696572154041
TF TF:M09765 Factor: SP1; motif: NRGKGGGCGGGGCN 0.0245036152340703 7469 29 20 0.689655172413793 0.00267773463649752
TF TF:M00971 Factor: Ets; motif: ACTTCCTS 0.0248340902256583 2349 27 10 0.37037037037037 0.0042571306939123
TF TF:M03852_1 Factor: SREBP-2; motif: NTCACCYNNNN; match class: 1 0.0248340902256583 2246 15 7 0.466666666666667 0.0031166518254675
TF TF:M12164 Factor: BTEB2; motif: NMCACGCCCN 0.0248340902256583 2984 22 10 0.454545454545455 0.00335120643431635
TF TF:M00721 Factor: CACCC-binding; motif: CANCCNNWGGGTGDGG 0.0248347507374266 2925 30 12 0.4 0.0041025641025641
TF TF:M08923 Factor: JUNB:FRA-2; motif: NRTGASTCAT 0.0248347507374266 2927 30 12 0.4 0.00409976084728391
TF TF:M08214 Factor: Elk-1:ETV7; motif: ANSCGGACGGATDTCCGGNT 0.025291880142953 7951 26 19 0.730769230769231 0.00238963652370771
TF TF:M00427 Factor: E2F; motif: TTTSGCGS 0.0253148027024703 9485 20 17 0.85 0.00179230363732209
TF TF:M02104 Factor: NF-E2; motif: CATGACTCAGCANNCN 0.0257319227478807 1146 4 3 0.75 0.00261780104712042
TF TF:M09965_1 Factor: c-Jun; motif: NRTGAGTCAYN; match class: 1 0.0257319227478807 681 6 3 0.5 0.00440528634361234
TF TF:M08487 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG 0.0257319227478807 13942 28 27 0.964285714285714 0.00193659446277435
TF TF:M00032 Factor: c-Ets-1(p54); motif: NCMGGAWGYN 0.0265383418525957 7858 21 16 0.761904761904762 0.00203614151183507
TF TF:M00736 Factor: E2F-1:DP-1; motif: TTTCSCGC 0.0266737656394703 10390 19 17 0.894736842105263 0.00163618864292589
TF TF:M07600_1 Factor: C-Fos; motif: NNTGACTCAN; match class: 1 0.0266737656394703 279 30 4 0.133333333333333 0.014336917562724
TF TF:M12119 Factor: FPM315; motif: NGTGCTCCCN 0.0266852274295471 1239 19 6 0.315789473684211 0.00484261501210654
TF TF:M00037 Factor: NF-E2; motif: TGCTGAGTCAY 0.0266852274295471 6629 30 19 0.633333333333333 0.00286619399607784
TF TF:M00706 Factor: TFII-I; motif: RGAGGKAGG 0.0266852274295471 5714 29 17 0.586206896551724 0.00297514875743787
TF TF:M00925 Factor: AP-1; motif: NTGACTCAN 0.027831053711529 2554 30 11 0.366666666666667 0.0043069694596711
TF TF:M04953 Factor: Sp1; motif: GGNDGGRGGCGGGG 0.0282008264956034 8688 28 21 0.75 0.0024171270718232
TF TF:M10432 Factor: MAZ; motif: GGGMGGGGS 0.0282008264956034 9259 30 23 0.766666666666667 0.00248406955394751
TF TF:M09965 Factor: c-Jun; motif: NRTGAGTCAYN 0.0290985452328775 4492 27 14 0.518518518518518 0.0031166518254675
TF TF:M08925 Factor: JUNB:C-FOS; motif: NATGAGTCATNN 0.0301219727330131 3490 30 13 0.433333333333333 0.00372492836676218
TF TF:M10074 Factor: Spi-B; motif: NRAAAGAGGAAGTGARA 0.03102891978542 1611 21 7 0.333333333333333 0.00434512725015518
TF TF:M00982 Factor: KROX; motif: CCCGCCCCCRCCCC 0.0317252879012466 7815 25 18 0.72 0.00230326295585413
TF TF:M10550_1 Factor: ZNF684; motif: MAAGGGGTGGACTGT; match class: 1 0.0317252879012466 9336 19 16 0.842105263157895 0.00171379605826907
TF TF:M10435 Factor: Sp2; motif: GGGGCGGGG 0.0317252879012466 7696 29 20 0.689655172413793 0.0025987525987526
TF TF:M07063 Factor: Sp1; motif: GGGGCGGGGC 0.0317252879012466 7696 29 20 0.689655172413793 0.0025987525987526
TF TF:M11297 Factor: jdp2; motif: NRTGASTCAYN 0.0322732898358086 1811 30 9 0.3 0.00496963003865268
TF TF:M09968 Factor: KLF15; motif: RGGGMGGRGNNGGGGGNGG 0.0322732898358086 3157 22 10 0.454545454545455 0.0031675641431739
TF TF:M10040 Factor: Blimp-1; motif: RAAAGNGAAAGTNN 0.0322732898358086 366 25 4 0.16 0.0109289617486339
TF TF:M09907_1 Factor: Erg; motif: NRRSAGGAAGNGG; match class: 1 0.0324002056987841 5070 30 16 0.533333333333333 0.00315581854043392
TF TF:M00761 Factor: p53; motif: RGRCAWGNCY 0.0324002056987841 2985 16 8 0.5 0.00268006700167504
TF TF:M09970 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN 0.0324002056987841 7728 29 20 0.689655172413793 0.0025879917184265
TF TF:M03811_1 Factor: AP-2gamma; motif: GCCYNCRGSN; match class: 1 0.0324002056987841 3812 25 12 0.48 0.00314795383001049
TF TF:M01652 Factor: p53; motif: RGRCWWGYCYNGRCWWGYYY 0.0337111342284422 8083 16 13 0.8125 0.0016083137448967
TF TF:M03990_1 Factor: GABPA; motif: ACCGGAAGTN; match class: 1 0.0337111342284422 1206 28 7 0.25 0.00580431177446103
TF TF:M11417 Factor: c-Ets-2; motif: NACCGGAAGYRCTTCCGGTN 0.0337111342284422 14334 21 21 1 0.00146504813729594
TF TF:M00431 Factor: E2F-1; motif: TTTSGCGS 0.0337111342284422 7257 19 14 0.736842105263158 0.00192917183409122
TF TF:M11288_1 Factor: ATF-3; motif: GATGAYGTCATN; match class: 1 0.0337111342284422 1624 16 6 0.375 0.00369458128078818
TF TF:M02022 Factor: MafK; motif: TGASTCAGCDN 0.0337111342284422 311 30 4 0.133333333333333 0.0128617363344051
TF TF:M09617 Factor: c-Fos; motif: RTGAGTCAYNN 0.0337111342284422 2663 30 11 0.366666666666667 0.00413067968456628
TF TF:M11291_1 Factor: ATF-3; motif: NRTGACGTCAYN; match class: 1 0.0339236988316928 4408 17 10 0.588235294117647 0.00226860254083485
TF TF:M09995 Factor: MZF-1; motif: NRNRGGGAWTNRN 0.0342033183933705 1662 27 8 0.296296296296296 0.00481347773766546
TF TF:M00215 Factor: SRF; motif: DCCWTATATGGNCWN 0.0342033183933705 147 29 3 0.103448275862069 0.0204081632653061
TF TF:M11264 Factor: c-Jun; motif: NATGASTCATN 0.0342033183933705 4600 30 15 0.5 0.00326086956521739
TF TF:M00749 Factor: SREBP-1; motif: CACSCCA 0.0342033183933705 8584 8 8 1 0.000931966449207828
TF TF:M04693 Factor: c-Fos; motif: RTGASTCAY 0.0342033183933705 2678 30 11 0.366666666666667 0.0041075429424944
TF TF:M04515 Factor: E2F-1; motif: WWTGGCGCCAAA 0.0342033183933705 13334 29 27 0.931034482758621 0.00202489875506225
TF TF:M12153 Factor: Sp3; motif: NGCCACGCCCMCN 0.0344740963474123 6205 28 17 0.607142857142857 0.00273972602739726
TF TF:M08441_1 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG; match class: 1 0.0344740963474123 12761 21 20 0.952380952380952 0.00156727529190502
TF TF:M11289_1 Factor: ATF-3; motif: NRTGACGTCAYN; match class: 1 0.0348361120353753 1661 16 6 0.375 0.00361228175797712
TF TF:M03819_1 Factor: Elk-1; motif: GGAAGN; match class: 1 0.0348361120353753 7491 30 20 0.666666666666667 0.0026698705112802
TF TF:M09615 Factor: Fra-1; motif: NRTGACTCATN 0.0350112058596773 4111 30 14 0.466666666666667 0.00340549744587692
TF TF:M00341 Factor: GABP; motif: VCCGGAAGNGCR 0.0351054425520404 8224 28 20 0.714285714285714 0.00243190661478599
TF TF:M09984 Factor: MAZ; motif: GGGGGAGGGGGNGRGRRRGNRG 0.0351054425520404 9544 16 14 0.875 0.00146689019279128
TF TF:M07092 Factor: Fra-2; motif: NRRTGASTCAB 0.0351054425520404 3156 30 12 0.4 0.00380228136882129
TF TF:M08920 Factor: JUNB:FOSB; motif: NRTGASTCAT 0.0351054425520404 3151 30 12 0.4 0.00380831482069184
TF TF:M09729_1 Factor: LUMAN; motif: CYCAGCYYCY; match class: 1 0.0354519292356284 4645 30 15 0.5 0.00322927879440258
TF TF:M03870 Factor: Fra-2; motif: TGASTCANCN 0.0354519292356284 3634 30 13 0.433333333333333 0.00357732526141992
TF TF:M09999 Factor: Nrf2; motif: WWNTGCTGAGTCAT 0.0354519292356284 2658 5 4 0.8 0.00150489089541008
TF TF:M10144_1 Factor: ZNF341; motif: GRGGRRNRGNRGNRGGAASAGC; match class: 1 0.0354519292356284 972 11 4 0.363636363636364 0.00411522633744856
TF TF:M09964_1 Factor: JunD; motif: NRTGAGTCAYN; match class: 1 0.0354519292356284 854 6 3 0.5 0.00351288056206089
TF TF:M07121 Factor: Blimp-1; motif: NRAAAGTGAAAGTNN 0.0360921827460316 401 25 4 0.16 0.00997506234413965
TF TF:M08929 Factor: JUND:FRA-1; motif: NRTGACTCAN 0.0360921827460316 1560 23 7 0.304347826086957 0.00448717948717949
TF TF:M11530_1 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN; match class: 1 0.0364720206149152 13449 29 27 0.931034482758621 0.00200758420700424
TF TF:M08881 Factor: ETSLIKE; motif: NACTTCCTNN 0.0367227399393423 3140 16 8 0.5 0.00254777070063694
TF TF:M11417_1 Factor: c-Ets-2; motif: NACCGGAAGYRCTTCCGGTN; match class: 1 0.0367227399393423 14041 19 19 1 0.0013531799729364
TF TF:M00008 Factor: Sp1; motif: GGGGCGGGGT 0.0374965746004616 10055 29 23 0.793103448275862 0.00228741919443063
TF TF:M00658_1 Factor: PU.1; motif: WGAGGAAG; match class: 1 0.0383783703697997 638 8 3 0.375 0.00470219435736677
TF TF:M00174 Factor: AP-1; motif: NNTGACTCANN 0.0383783703697997 1921 30 9 0.3 0.00468505986465383
TF TF:M06948_1 Factor: Sp2; motif: TGGGCGCGCCCA; match class: 1 0.0385029078399935 6205 24 15 0.625 0.0024174053182917
TF TF:M00517_1 Factor: AP-1; motif: NNNTGAGTCAKCN; match class: 1 0.0387435558464071 3227 30 12 0.4 0.00371862410907964
TF TF:M05775 Factor: ZXDL; motif: NGGGGWS 0.0387435558464071 6964 26 17 0.653846153846154 0.00244112578977599
TF TF:M00152 Factor: SRF; motif: ATGCCCATATATGGWNNT 0.0387435558464071 182 26 3 0.115384615384615 0.0164835164835165
TF TF:M00739 Factor: E2F-4:DP-2; motif: TTTCSCGC 0.0389869572545339 5624 19 12 0.631578947368421 0.00213371266002845
TF TF:M02078 Factor: SPI1; motif: NGRGGAAGTN 0.0393359149240473 3506 28 12 0.428571428571429 0.00342270393610953
TF TF:M08944_1 Factor: JUNB:C-JUN; motif: NATGACKCAT; match class: 1 0.0395395666918044 933 6 3 0.5 0.00321543408360129
TF TF:M09762_1 Factor: NF1B; motif: CYTGGCNYNCWGCCAN; match class: 1 0.0395395666918044 1514 8 4 0.5 0.00264200792602378
TF TF:M03791_1 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY; match class: 1 0.0395395666918044 429 25 4 0.16 0.00932400932400932
TF TF:M08306 Factor: GCMa:Elf-1; motif: NNCGGAARTGCKGGT 0.0395395666918044 2776 18 8 0.444444444444444 0.00288184438040346
TF TF:M09723 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS 0.0395395666918044 10156 29 23 0.793103448275862 0.00226467113036629
TF TF:M12188 Factor: KLF17; motif: NGMCMCRCCCTN 0.0395395666918044 3673 27 12 0.444444444444444 0.00326708412741628
TF TF:M03551 Factor: JunB; motif: TGACTCAN 0.0395395666918044 4253 30 14 0.466666666666667 0.00329179402774512
TF TF:M00803 Factor: E2F; motif: GGCGSG 0.0395395666918044 13190 27 25 0.925925925925926 0.00189537528430629
TF TF:M08933 Factor: JUND:C-FOS; motif: NNATGAGTCATNN 0.0395395666918044 4818 27 14 0.518518518518518 0.0029057700290577
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 0.0395395666918044 13929 25 24 0.96 0.00172302390695671
TF TF:M08936 Factor: C-JUN:FOSB; motif: NATGACTCAY 0.0395395666918044 3271 30 12 0.4 0.00366860287373892
TF TF:M00008_1 Factor: Sp1; motif: GGGGCGGGGT; match class: 1 0.0395395666918044 4937 29 15 0.517241379310345 0.00303828235770711
TF TF:M06479 Factor: HZF12; motif: NYCTCCGGRTGA 0.0395395666918044 276 18 3 0.166666666666667 0.0108695652173913
TF TF:M01172 Factor: PU.1; motif: NNNNYYYACTTCCTCTTTY 0.0395395666918044 4281 8 6 0.75 0.00140154169586545
TF TF:M02089_1 Factor: E2F-3; motif: GGCGGGN; match class: 1 0.0395395666918044 9362 12 11 0.916666666666667 0.00117496261482589
TF TF:M07048_1 Factor: MafG; motif: CMATGACTCAGCAGA; match class: 1 0.0395395666918044 1550 18 6 0.333333333333333 0.00387096774193548
TF TF:M02280 Factor: AP1; motif: TGACTCA 0.0395395666918044 4255 30 14 0.466666666666667 0.00329024676850764
TF TF:M03835 Factor: Nrf2; motif: ACNRTGACTCAGCANWA 0.0395395666918044 1562 4 3 0.75 0.00192061459667093
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.0395395666918044 14593 29 28 0.96551724137931 0.00191872815733571
TF TF:M08623 Factor: rfx3:SRF; motif: TRGCAACNNNNNCCNWATANGGN 0.0397100029624974 14645 29 28 0.96551724137931 0.00191191532946398
TF TF:M03821_1 Factor: ER-beta; motif: ANNSTGACCYRGNN; match class: 1 0.0397217583809938 1368 27 7 0.259259259259259 0.00511695906432749
TF TF:M07261_1 Factor: LKLF; motif: GGGGTGGKSN; match class: 1 0.0398089785998313 4062 19 10 0.526315789473684 0.00246184145741014
TF TF:M00199_1 Factor: AP-1; motif: NTGASTCAG; match class: 1 0.0398089785998313 4265 30 14 0.466666666666667 0.00328253223915592
TF TF:M08942 Factor: C-FOS:C-JUN; motif: ATGAGTCAYN 0.0401753730433631 3289 30 12 0.4 0.00364852538765582
TF TF:M00933 Factor: Sp1; motif: CCCCGCCCCN 0.0401753730433631 9715 30 23 0.766666666666667 0.00236747297992795
TF TF:M07409_1 Factor: BTEB2; motif: GCCCCRCCCH; match class: 1 0.0404922643797341 1829 7 4 0.571428571428571 0.00218698742482231
TF TF:M00738 Factor: E2F-4:DP-1; motif: TTTSGCGC 0.0405315927567116 9812 19 16 0.842105263157895 0.00163065633917652
TF TF:M03870_1 Factor: Fra-2; motif: TGASTCANCN; match class: 1 0.0407475770430512 902 30 6 0.2 0.00665188470066519
TF TF:M10121_1 Factor: ZFX; motif: SNAGGCCNCR; match class: 1 0.0415297076507104 813 23 5 0.217391304347826 0.00615006150061501
TF TF:M07251 Factor: EHF; motif: BTTCCTGC 0.0417071263853882 6174 18 12 0.666666666666667 0.00194363459669582
TF TF:M09984_1 Factor: MAZ; motif: GGGGGAGGGGGNGRGRRRGNRG; match class: 1 0.0417071263853882 5555 15 10 0.666666666666667 0.0018001800180018
TF TF:M11291 Factor: ATF-3; motif: NRTGACGTCAYN 0.0417130598751661 4720 17 10 0.588235294117647 0.00211864406779661
TF TF:M07615 Factor: Sp3; motif: GGGGCGGGGSNN 0.0424198743483268 6807 29 18 0.620689655172414 0.00264433671220802
TF TF:M03553 Factor: KLF3; motif: CCMCACCCNG 0.0425226957041909 1873 7 4 0.571428571428571 0.00213561131873999
TF TF:M12158 Factor: KLF15; motif: NCCMCGCCCMCN 0.0425226957041909 11088 15 14 0.933333333333333 0.00126262626262626
TF TF:M00716 Factor: ZF5; motif: GSGCGCGR 0.0427496327527625 16103 30 30 1 0.0018630068931255
TF TF:M09760 Factor: DPF2; motif: NYCACYTCCYCNYYCY 0.0427496327527625 8179 27 19 0.703703703703704 0.0023230223743734
TF TF:M08934 Factor: JUND; motif: NATGAGTCAT 0.0429931249046975 4329 30 14 0.466666666666667 0.00323400323400323
TF TF:M03567_1 Factor: Sp2; motif: NYSGCCCCGCCCCCY; match class: 1 0.0429931249046975 3614 12 7 0.583333333333333 0.00193691200885445
TF TF:M04711 Factor: PU.1; motif: ACTTCCTCT 0.0429931249046975 1712 12 5 0.416666666666667 0.00292056074766355
TF TF:M08208 Factor: E2F-3:FOXI1; motif: NGACACCGCGCCCAC 0.0430571541491416 12560 28 25 0.892857142857143 0.00199044585987261
TF TF:M09923 Factor: Fra-2; motif: NNRTGAGTCAYN 0.0430571541491416 4336 30 14 0.466666666666667 0.00322878228782288
TF TF:M12151 Factor: Sp1; motif: NWRGCCMCGCCCMCN 0.0430571541491416 6821 27 17 0.62962962962963 0.00249230318135171
TF TF:M08928 Factor: FOSB:JUND; motif: NNTNACTNATN 0.0430571541491416 6164 27 16 0.592592592592593 0.00259571706683971
TF TF:M02263 Factor: NFE2L2; motif: RTGACWCAGCA 0.0430571541491416 3025 5 4 0.8 0.00132231404958678
TF TF:M11289 Factor: ATF-3; motif: NRTGACGTCAYN 0.0430571541491416 4773 17 10 0.588235294117647 0.00209511837418814
TF TF:M09902 Factor: ESE-1; motif: NNANVAGGAAGTNN 0.0430571541491416 3200 20 9 0.45 0.0028125
TF TF:M01165_1 Factor: Elk-1; motif: RACCGGAAGTR; match class: 1 0.0430571541491416 2185 28 9 0.321428571428571 0.00411899313501144
TF TF:M12026_1 Factor: TBX2; motif: NNNGTGTSNN; match class: 1 0.0430571541491416 1911 7 4 0.571428571428571 0.00209314495028781
TF TF:M00426 Factor: E2F; motif: TTTSGCGS 0.0430571541491416 11885 29 25 0.862068965517241 0.00210349179638199
TF TF:M09746_1 Factor: HNRPUL1; motif: NCNCAGN; match class: 1 0.0430571541491416 7619 21 15 0.714285714285714 0.0019687623047644
TF TF:M07277_1 Factor: BTEB2; motif: RGGGNGKGGN; match class: 1 0.0430571541491416 4149 25 12 0.48 0.00289226319595083
TF TF:M12217 Factor: GLIS2; motif: ACCCCCCRCGWNGC 0.0431606668326715 567 10 3 0.3 0.00529100529100529
TF TF:M11376 Factor: Spi-B; motif: RAAWGRGGAAGTN 0.0432013385827105 729 8 3 0.375 0.00411522633744856
TF TF:M02111_1 Factor: NR1B2; motif: NTGACCY; match class: 1 0.0434197189975613 3323 23 10 0.434782608695652 0.00300932891965092
TF TF:M10014 Factor: FXR; motif: NRGGKCANTGRCCNNNNGG 0.0437387266524645 5652 15 10 0.666666666666667 0.00176928520877565
TF TF:M07129 Factor: Sp2; motif: GYCCCGCCYCYNNNN 0.0437728003729445 6260 29 17 0.586206896551724 0.00271565495207668
TF TF:M03574 Factor: GCMa; motif: CCCGCAT 0.0437728003729445 2362 6 4 0.666666666666667 0.00169348010160881
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.0440968503369052 8180 29 20 0.689655172413793 0.00244498777506112
TF TF:M10076 Factor: SRF; motif: TTNCCWTWTWTGGNCWNN 0.0440968503369052 187 29 3 0.103448275862069 0.0160427807486631
TF TF:M09967 Factor: AP-2rep; motif: NGGGGCGGGGC 0.0442374795780944 4023 29 13 0.448275862068966 0.00323141933880189
TF TF:M05327_1 Factor: WT1; motif: NGCGGGGGGGTSMMCYN; match class: 1 0.0443625671914693 1757 12 5 0.416666666666667 0.00284575981787137
TF TF:M01242_1 Factor: MTF-1; motif: GTGTGCANMACTTTGCGCAC; match class: 1 0.0443982999920349 701 17 4 0.235294117647059 0.00570613409415121
TF TF:M03797 Factor: Msx-2; motif: TWWTTGGDGABN 0.0444895995038786 4889 12 8 0.666666666666667 0.0016363264471262
TF TF:M12165 Factor: BTEB2; motif: NCCACRCCCN 0.0458165755820137 4901 22 12 0.545454545454545 0.0024484799020608
TF TF:M04617_1 Factor: LRF; motif: NGNAGNGGGTYN; match class: 1 0.0461463367938669 1454 9 4 0.444444444444444 0.00275103163686382
TF TF:M01733 Factor: MZF-1; motif: TGGGGAR 0.046426819907565 11391 30 25 0.833333333333333 0.00219471512597665
TF TF:M09837_1 Factor: ZNF449; motif: NNNAGCCCARCC; match class: 1 0.0468089561258123 764 8 3 0.375 0.00392670157068063
TF TF:M07292 Factor: GLI; motif: NTGGGTGGTN 0.0481777994896938 5763 15 10 0.666666666666667 0.00173520735727919
TF TF:M11533_1 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN; match class: 1 0.0481777994896938 8705 21 16 0.761904761904762 0.00183802412406663
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.0483137611583828 16244 30 30 1 0.00184683575474021
TF TF:M08933_1 Factor: JUND:C-FOS; motif: NNATGAGTCATNN; match class: 1 0.0484004430018311 1312 30 7 0.233333333333333 0.00533536585365854
TF TF:M00001 Factor: MyoD; motif: SRACAGGTGKYG 0.0484004430018311 1365 5 3 0.6 0.0021978021978022
TF TF:M01721_1 Factor: PUR1; motif: GGGNCAGNN; match class: 1 0.0491026105841099 3414 23 10 0.434782608695652 0.00292911540714704
TF TF:M09659 Factor: PU.1; motif: NRAAAGAGGAAGTGARA 0.0494637572477032 2523 21 8 0.380952380952381 0.00317082837891399
WP WP:WP3888 VEGFA-VEGFR2 Signaling Pathway 9.56075700195669e-05 437 28 10 0.357142857142857 0.022883295194508
WP WP:WP98 Prostaglandin Synthesis and Regulation 9.84623234112166e-05 45 6 3 0.5 0.0666666666666667
WP WP:WP2272 Pathogenic Escherichia coli infection 0.000336981252753714 55 23 4 0.173913043478261 0.0727272727272727
WP WP:WP51 Regulation of Actin Cytoskeleton 0.000884050160946299 149 23 5 0.217391304347826 0.0335570469798658
WP WP:WP306 Focal Adhesion 0.02110672756959 201 25 4 0.16 0.0199004975124378
WP WP:WP4217 Ebola Virus Pathway on Host 0.024735886314193 130 23 3 0.130434782608696 0.0230769230769231
WP WP:WP289 Myometrial Relaxation and Contraction Pathways 0.0280424699493868 155 23 3 0.130434782608696 0.0193548387096774

pEpiTp22 transcription factor target enrichment of top program genes

TF enrichment of pEpiTp22
Possible regulators of activation of pEpiTp22 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.