GO:BP
|
GO:0019221
|
cytokine-mediated signaling pathway
|
9.61002240353026e-11
|
810
|
10
|
10
|
1
|
0.0123456790123457
|
GO:BP
|
GO:0071345
|
cellular response to cytokine stimulus
|
1.97440837273983e-10
|
1132
|
146
|
37
|
0.253424657534247
|
0.0326855123674912
|
GO:BP
|
GO:0034097
|
response to cytokine
|
2.95672788115369e-10
|
1226
|
146
|
38
|
0.26027397260274
|
0.0309951060358891
|
GO:BP
|
GO:0042110
|
T cell activation
|
5.74851874171838e-10
|
489
|
85
|
19
|
0.223529411764706
|
0.0388548057259714
|
GO:BP
|
GO:0046649
|
lymphocyte activation
|
5.74851874171838e-10
|
771
|
86
|
23
|
0.267441860465116
|
0.0298313878080415
|
GO:BP
|
GO:0050863
|
regulation of T cell activation
|
2.96988674948613e-09
|
337
|
133
|
19
|
0.142857142857143
|
0.056379821958457
|
GO:BP
|
GO:0002703
|
regulation of leukocyte mediated immunity
|
6.48925292283054e-09
|
205
|
129
|
15
|
0.116279069767442
|
0.0731707317073171
|
GO:BP
|
GO:0002694
|
regulation of leukocyte activation
|
6.48925292283054e-09
|
610
|
134
|
24
|
0.17910447761194
|
0.039344262295082
|
GO:BP
|
GO:0045321
|
leukocyte activation
|
6.48925292283054e-09
|
1332
|
146
|
37
|
0.253424657534247
|
0.0277777777777778
|
GO:BP
|
GO:0001816
|
cytokine production
|
7.95705370013863e-09
|
844
|
146
|
29
|
0.198630136986301
|
0.0343601895734597
|
GO:BP
|
GO:0001775
|
cell activation
|
7.95705370013863e-09
|
1495
|
146
|
39
|
0.267123287671233
|
0.0260869565217391
|
GO:BP
|
GO:0051249
|
regulation of lymphocyte activation
|
8.51750742216547e-09
|
518
|
134
|
22
|
0.164179104477612
|
0.0424710424710425
|
GO:BP
|
GO:0007159
|
leukocyte cell-cell adhesion
|
8.73876331512886e-09
|
375
|
133
|
19
|
0.142857142857143
|
0.0506666666666667
|
GO:BP
|
GO:0002682
|
regulation of immune system process
|
9.83778742722768e-09
|
1617
|
144
|
40
|
0.277777777777778
|
0.0247371675943105
|
GO:BP
|
GO:0002376
|
immune system process
|
1.1954157512205e-08
|
3278
|
146
|
60
|
0.410958904109589
|
0.0183038438071995
|
GO:BP
|
GO:0002705
|
positive regulation of leukocyte mediated immunity
|
1.1954157512205e-08
|
122
|
129
|
12
|
0.0930232558139535
|
0.0983606557377049
|
GO:BP
|
GO:0002706
|
regulation of lymphocyte mediated immunity
|
1.1954157512205e-08
|
151
|
129
|
13
|
0.10077519379845
|
0.0860927152317881
|
GO:BP
|
GO:0033209
|
tumor necrosis factor-mediated signaling pathway
|
1.1954157512205e-08
|
177
|
9
|
6
|
0.666666666666667
|
0.0338983050847458
|
GO:BP
|
GO:0050865
|
regulation of cell activation
|
1.31837129504067e-08
|
655
|
134
|
24
|
0.17910447761194
|
0.0366412213740458
|
GO:BP
|
GO:0002822
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
1.34249443321455e-08
|
152
|
82
|
11
|
0.134146341463415
|
0.0723684210526316
|
GO:BP
|
GO:0002449
|
lymphocyte mediated immunity
|
1.35564951659466e-08
|
354
|
85
|
15
|
0.176470588235294
|
0.0423728813559322
|
GO:BP
|
GO:0001817
|
regulation of cytokine production
|
1.57843773448503e-08
|
806
|
131
|
26
|
0.198473282442748
|
0.032258064516129
|
GO:BP
|
GO:0010033
|
response to organic substance
|
1.57843773448503e-08
|
3412
|
146
|
61
|
0.417808219178082
|
0.0178780773739742
|
GO:BP
|
GO:0002460
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
1.68505052532485e-08
|
363
|
85
|
15
|
0.176470588235294
|
0.0413223140495868
|
GO:BP
|
GO:0002819
|
regulation of adaptive immune response
|
2.96365587108118e-08
|
167
|
82
|
11
|
0.134146341463415
|
0.0658682634730539
|
GO:BP
|
GO:0071310
|
cellular response to organic substance
|
4.37667381360393e-08
|
2776
|
146
|
53
|
0.363013698630137
|
0.0190922190201729
|
GO:BP
|
GO:0002824
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
5.2438698400378e-08
|
96
|
82
|
9
|
0.109756097560976
|
0.09375
|
GO:BP
|
GO:1903131
|
mononuclear cell differentiation
|
5.2438698400378e-08
|
430
|
79
|
15
|
0.189873417721519
|
0.0348837209302326
|
GO:BP
|
GO:1903037
|
regulation of leukocyte cell-cell adhesion
|
5.2438698400378e-08
|
338
|
133
|
17
|
0.12781954887218
|
0.0502958579881657
|
GO:BP
|
GO:0002440
|
production of molecular mediator of immune response
|
6.14092036971039e-08
|
189
|
79
|
11
|
0.139240506329114
|
0.0582010582010582
|
GO:BP
|
GO:0002821
|
positive regulation of adaptive immune response
|
7.69825922781012e-08
|
101
|
82
|
9
|
0.109756097560976
|
0.0891089108910891
|
GO:BP
|
GO:0002456
|
T cell mediated immunity
|
7.69825922781012e-08
|
98
|
85
|
9
|
0.105882352941176
|
0.0918367346938776
|
GO:BP
|
GO:0030098
|
lymphocyte differentiation
|
7.69825922781012e-08
|
376
|
79
|
14
|
0.177215189873418
|
0.0372340425531915
|
GO:BP
|
GO:0002700
|
regulation of production of molecular mediator of immune response
|
8.10128905319551e-08
|
148
|
79
|
10
|
0.126582278481013
|
0.0675675675675676
|
GO:BP
|
GO:0006955
|
immune response
|
1.06067132041144e-07
|
2311
|
85
|
33
|
0.388235294117647
|
0.0142795326698399
|
GO:BP
|
GO:0002696
|
positive regulation of leukocyte activation
|
1.32322496380622e-07
|
412
|
134
|
18
|
0.134328358208955
|
0.0436893203883495
|
GO:BP
|
GO:0071356
|
cellular response to tumor necrosis factor
|
1.52786324574225e-07
|
306
|
9
|
6
|
0.666666666666667
|
0.0196078431372549
|
GO:BP
|
GO:0050867
|
positive regulation of cell activation
|
1.97296709721093e-07
|
424
|
134
|
18
|
0.134328358208955
|
0.0424528301886792
|
GO:BP
|
GO:0002250
|
adaptive immune response
|
2.00793702612549e-07
|
689
|
85
|
18
|
0.211764705882353
|
0.0261248185776488
|
GO:BP
|
GO:0070887
|
cellular response to chemical stimulus
|
2.06878929051297e-07
|
3393
|
146
|
58
|
0.397260273972603
|
0.0170940170940171
|
GO:BP
|
GO:0034612
|
response to tumor necrosis factor
|
2.20904566701311e-07
|
331
|
9
|
6
|
0.666666666666667
|
0.0181268882175227
|
GO:BP
|
GO:0002708
|
positive regulation of lymphocyte mediated immunity
|
2.63886834100113e-07
|
104
|
129
|
10
|
0.0775193798449612
|
0.0961538461538462
|
GO:BP
|
GO:0042098
|
T cell proliferation
|
2.73067992237997e-07
|
205
|
133
|
13
|
0.0977443609022556
|
0.0634146341463415
|
GO:BP
|
GO:0045785
|
positive regulation of cell adhesion
|
2.74786238834703e-07
|
437
|
18
|
8
|
0.444444444444444
|
0.0183066361556064
|
GO:BP
|
GO:0002724
|
regulation of T cell cytokine production
|
2.9365713810091e-07
|
33
|
75
|
6
|
0.08
|
0.181818181818182
|
GO:BP
|
GO:0002699
|
positive regulation of immune effector process
|
3.12045120864939e-07
|
215
|
129
|
13
|
0.10077519379845
|
0.0604651162790698
|
GO:BP
|
GO:0002697
|
regulation of immune effector process
|
3.18370088960148e-07
|
461
|
129
|
18
|
0.13953488372093
|
0.0390455531453362
|
GO:BP
|
GO:0012501
|
programmed cell death
|
3.28736489406997e-07
|
2143
|
134
|
41
|
0.305970149253731
|
0.0191320578628091
|
GO:BP
|
GO:0050870
|
positive regulation of T cell activation
|
3.95627568396527e-07
|
219
|
85
|
11
|
0.129411764705882
|
0.0502283105022831
|
GO:BP
|
GO:0042129
|
regulation of T cell proliferation
|
4.26338407549015e-07
|
176
|
133
|
12
|
0.0902255639097744
|
0.0681818181818182
|
GO:BP
|
GO:0006915
|
apoptotic process
|
4.32574763891708e-07
|
1990
|
134
|
39
|
0.291044776119403
|
0.0195979899497487
|
GO:BP
|
GO:0002369
|
T cell cytokine production
|
4.42550419972957e-07
|
36
|
75
|
6
|
0.08
|
0.166666666666667
|
GO:BP
|
GO:0043067
|
regulation of programmed cell death
|
5.36515105962663e-07
|
1582
|
134
|
34
|
0.253731343283582
|
0.0214917825537295
|
GO:BP
|
GO:0030217
|
T cell differentiation
|
5.51214982299038e-07
|
260
|
75
|
11
|
0.146666666666667
|
0.0423076923076923
|
GO:BP
|
GO:0008219
|
cell death
|
6.22971394211975e-07
|
2292
|
134
|
42
|
0.313432835820896
|
0.0183246073298429
|
GO:BP
|
GO:0002521
|
leukocyte differentiation
|
6.98039666929897e-07
|
550
|
79
|
15
|
0.189873417721519
|
0.0272727272727273
|
GO:BP
|
GO:0051251
|
positive regulation of lymphocyte activation
|
6.98039666929897e-07
|
365
|
134
|
16
|
0.119402985074627
|
0.0438356164383562
|
GO:BP
|
GO:0080134
|
regulation of response to stress
|
6.98039666929897e-07
|
1443
|
82
|
24
|
0.292682926829268
|
0.0166320166320166
|
GO:BP
|
GO:0050670
|
regulation of lymphocyte proliferation
|
7.94270892834028e-07
|
230
|
133
|
13
|
0.0977443609022556
|
0.0565217391304348
|
GO:BP
|
GO:0002517
|
T cell tolerance induction
|
8.44543079399421e-07
|
14
|
38
|
4
|
0.105263157894737
|
0.285714285714286
|
GO:BP
|
GO:1903039
|
positive regulation of leukocyte cell-cell adhesion
|
8.44543079399421e-07
|
241
|
85
|
11
|
0.129411764705882
|
0.045643153526971
|
GO:BP
|
GO:0032944
|
regulation of mononuclear cell proliferation
|
8.44543079399421e-07
|
232
|
133
|
13
|
0.0977443609022556
|
0.0560344827586207
|
GO:BP
|
GO:0048518
|
positive regulation of biological process
|
1.0613180795628e-06
|
6363
|
137
|
80
|
0.583941605839416
|
0.0125726858400126
|
GO:BP
|
GO:0002709
|
regulation of T cell mediated immunity
|
1.11990301849779e-06
|
74
|
75
|
7
|
0.0933333333333333
|
0.0945945945945946
|
GO:BP
|
GO:0022407
|
regulation of cell-cell adhesion
|
1.40298782154859e-06
|
445
|
133
|
17
|
0.12781954887218
|
0.0382022471910112
|
GO:BP
|
GO:0007166
|
cell surface receptor signaling pathway
|
1.4504698196677e-06
|
3210
|
10
|
10
|
1
|
0.00311526479750779
|
GO:BP
|
GO:0045589
|
regulation of regulatory T cell differentiation
|
1.66037737485178e-06
|
35
|
18
|
4
|
0.222222222222222
|
0.114285714285714
|
GO:BP
|
GO:0070663
|
regulation of leukocyte proliferation
|
1.94024963320643e-06
|
251
|
133
|
13
|
0.0977443609022556
|
0.051792828685259
|
GO:BP
|
GO:0009893
|
positive regulation of metabolic process
|
1.95485552369661e-06
|
3783
|
135
|
56
|
0.414814814814815
|
0.0148030663494581
|
GO:BP
|
GO:0002252
|
immune effector process
|
1.95485552369661e-06
|
1309
|
146
|
31
|
0.212328767123288
|
0.0236822001527884
|
GO:BP
|
GO:0002711
|
positive regulation of T cell mediated immunity
|
1.96349328671797e-06
|
48
|
75
|
6
|
0.08
|
0.125
|
GO:BP
|
GO:1902105
|
regulation of leukocyte differentiation
|
2.06994342470615e-06
|
288
|
79
|
11
|
0.139240506329114
|
0.0381944444444444
|
GO:BP
|
GO:0042981
|
regulation of apoptotic process
|
2.11272543486307e-06
|
1549
|
82
|
24
|
0.292682926829268
|
0.0154938670109748
|
GO:BP
|
GO:0010604
|
positive regulation of macromolecule metabolic process
|
2.11272543486307e-06
|
3483
|
135
|
53
|
0.392592592592593
|
0.0152167671547517
|
GO:BP
|
GO:0045066
|
regulatory T cell differentiation
|
2.11272543486307e-06
|
38
|
18
|
4
|
0.222222222222222
|
0.105263157894737
|
GO:BP
|
GO:0048522
|
positive regulation of cellular process
|
2.27719097175524e-06
|
5757
|
137
|
74
|
0.54014598540146
|
0.0128539169706444
|
GO:BP
|
GO:0002718
|
regulation of cytokine production involved in immune response
|
2.46231936817792e-06
|
85
|
75
|
7
|
0.0933333333333333
|
0.0823529411764706
|
GO:BP
|
GO:0002684
|
positive regulation of immune system process
|
2.47813502865272e-06
|
1065
|
134
|
26
|
0.194029850746269
|
0.0244131455399061
|
GO:BP
|
GO:0010941
|
regulation of cell death
|
2.84471618592454e-06
|
1720
|
134
|
34
|
0.253731343283582
|
0.0197674418604651
|
GO:BP
|
GO:0022409
|
positive regulation of cell-cell adhesion
|
3.46554166454208e-06
|
284
|
85
|
11
|
0.129411764705882
|
0.0387323943661972
|
GO:BP
|
GO:0045619
|
regulation of lymphocyte differentiation
|
3.46554166454208e-06
|
180
|
79
|
9
|
0.113924050632911
|
0.05
|
GO:BP
|
GO:0002520
|
immune system development
|
3.99384659134767e-06
|
1020
|
82
|
19
|
0.231707317073171
|
0.0186274509803922
|
GO:BP
|
GO:0001819
|
positive regulation of cytokine production
|
4.35957524427528e-06
|
452
|
82
|
13
|
0.158536585365854
|
0.0287610619469027
|
GO:BP
|
GO:0002367
|
cytokine production involved in immune response
|
4.54423715252258e-06
|
94
|
75
|
7
|
0.0933333333333333
|
0.074468085106383
|
GO:BP
|
GO:0002443
|
leukocyte mediated immunity
|
5.12076259100713e-06
|
877
|
146
|
24
|
0.164383561643836
|
0.0273660205245154
|
GO:BP
|
GO:0050727
|
regulation of inflammatory response
|
5.12076259100713e-06
|
381
|
82
|
12
|
0.146341463414634
|
0.031496062992126
|
GO:BP
|
GO:0045580
|
regulation of T cell differentiation
|
5.66108184368859e-06
|
152
|
72
|
8
|
0.111111111111111
|
0.0526315789473684
|
GO:BP
|
GO:0002702
|
positive regulation of production of molecular mediator of immune response
|
6.65099557246635e-06
|
100
|
75
|
7
|
0.0933333333333333
|
0.07
|
GO:BP
|
GO:0048523
|
negative regulation of cellular process
|
7.3462202601205e-06
|
5139
|
83
|
46
|
0.55421686746988
|
0.00895115781280405
|
GO:BP
|
GO:0048534
|
hematopoietic or lymphoid organ development
|
8.39011864756078e-06
|
966
|
82
|
18
|
0.219512195121951
|
0.0186335403726708
|
GO:BP
|
GO:0006952
|
defense response
|
8.40728983699801e-06
|
1818
|
82
|
25
|
0.304878048780488
|
0.0137513751375138
|
GO:BP
|
GO:0007155
|
cell adhesion
|
8.41332066085194e-06
|
1492
|
146
|
32
|
0.219178082191781
|
0.0214477211796247
|
GO:BP
|
GO:0030155
|
regulation of cell adhesion
|
8.41332066085194e-06
|
748
|
18
|
8
|
0.444444444444444
|
0.0106951871657754
|
GO:BP
|
GO:0002480
|
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
|
8.73952962232229e-06
|
8
|
144
|
4
|
0.0277777777777778
|
0.5
|
GO:BP
|
GO:0046651
|
lymphocyte proliferation
|
8.73952962232229e-06
|
294
|
133
|
13
|
0.0977443609022556
|
0.0442176870748299
|
GO:BP
|
GO:0022610
|
biological adhesion
|
8.95944686073157e-06
|
1499
|
146
|
32
|
0.219178082191781
|
0.0213475650433622
|
GO:BP
|
GO:1903706
|
regulation of hemopoiesis
|
9.4014986238759e-06
|
424
|
79
|
12
|
0.151898734177215
|
0.0283018867924528
|
GO:BP
|
GO:0032943
|
mononuclear cell proliferation
|
9.40721191022032e-06
|
297
|
18
|
6
|
0.333333333333333
|
0.0202020202020202
|
GO:BP
|
GO:0002507
|
tolerance induction
|
1.19509848070359e-05
|
29
|
38
|
4
|
0.105263157894737
|
0.137931034482759
|
GO:BP
|
GO:0050776
|
regulation of immune response
|
1.19509848070359e-05
|
996
|
82
|
18
|
0.219512195121951
|
0.0180722891566265
|
GO:BP
|
GO:0070661
|
leukocyte proliferation
|
1.51893304802441e-05
|
325
|
18
|
6
|
0.333333333333333
|
0.0184615384615385
|
GO:BP
|
GO:0002486
|
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
|
1.51893304802441e-05
|
3
|
144
|
3
|
0.0208333333333333
|
1
|
GO:BP
|
GO:0002484
|
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
|
1.51893304802441e-05
|
3
|
144
|
3
|
0.0208333333333333
|
1
|
GO:BP
|
GO:0031347
|
regulation of defense response
|
1.62012201275727e-05
|
704
|
82
|
15
|
0.182926829268293
|
0.0213068181818182
|
GO:BP
|
GO:0048584
|
positive regulation of response to stimulus
|
1.73185499544113e-05
|
2344
|
134
|
39
|
0.291044776119403
|
0.0166382252559727
|
GO:BP
|
GO:0043281
|
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
1.96493547803992e-05
|
217
|
83
|
9
|
0.108433734939759
|
0.0414746543778802
|
GO:BP
|
GO:0042270
|
protection from natural killer cell mediated cytotoxicity
|
2.23267980766598e-05
|
6
|
62
|
3
|
0.0483870967741935
|
0.5
|
GO:BP
|
GO:0045058
|
T cell selection
|
2.23267980766598e-05
|
51
|
61
|
5
|
0.0819672131147541
|
0.0980392156862745
|
GO:BP
|
GO:0098609
|
cell-cell adhesion
|
2.23267980766598e-05
|
894
|
146
|
23
|
0.157534246575342
|
0.0257270693512304
|
GO:BP
|
GO:0050671
|
positive regulation of lymphocyte proliferation
|
2.4756740719579e-05
|
141
|
131
|
9
|
0.0687022900763359
|
0.0638297872340425
|
GO:BP
|
GO:0032946
|
positive regulation of mononuclear cell proliferation
|
2.60353915652076e-05
|
142
|
131
|
9
|
0.0687022900763359
|
0.0633802816901408
|
GO:BP
|
GO:0042113
|
B cell activation
|
2.97752368289229e-05
|
330
|
134
|
13
|
0.0970149253731343
|
0.0393939393939394
|
GO:BP
|
GO:0002707
|
negative regulation of lymphocyte mediated immunity
|
3.29542329012011e-05
|
43
|
79
|
5
|
0.0632911392405063
|
0.116279069767442
|
GO:BP
|
GO:0031348
|
negative regulation of defense response
|
3.39916670625038e-05
|
246
|
79
|
9
|
0.113924050632911
|
0.0365853658536585
|
GO:BP
|
GO:0002726
|
positive regulation of T cell cytokine production
|
3.44677573451498e-05
|
20
|
75
|
4
|
0.0533333333333333
|
0.2
|
GO:BP
|
GO:0032655
|
regulation of interleukin-12 production
|
3.65411036200074e-05
|
60
|
58
|
5
|
0.0862068965517241
|
0.0833333333333333
|
GO:BP
|
GO:0032615
|
interleukin-12 production
|
3.65411036200074e-05
|
60
|
58
|
5
|
0.0862068965517241
|
0.0833333333333333
|
GO:BP
|
GO:0030162
|
regulation of proteolysis
|
3.83737732239241e-05
|
752
|
83
|
15
|
0.180722891566265
|
0.0199468085106383
|
GO:BP
|
GO:2000116
|
regulation of cysteine-type endopeptidase activity
|
4.04637770906182e-05
|
240
|
83
|
9
|
0.108433734939759
|
0.0375
|
GO:BP
|
GO:0042221
|
response to chemical
|
4.26564031534786e-05
|
4781
|
146
|
65
|
0.445205479452055
|
0.013595482116712
|
GO:BP
|
GO:0002664
|
regulation of T cell tolerance induction
|
4.85234350274016e-05
|
12
|
38
|
3
|
0.0789473684210526
|
0.25
|
GO:BP
|
GO:0032663
|
regulation of interleukin-2 production
|
4.88332667072929e-05
|
61
|
61
|
5
|
0.0819672131147541
|
0.0819672131147541
|
GO:BP
|
GO:0070665
|
positive regulation of leukocyte proliferation
|
4.88332667072929e-05
|
155
|
131
|
9
|
0.0687022900763359
|
0.0580645161290323
|
GO:BP
|
GO:0030097
|
hemopoiesis
|
5.20917282661525e-05
|
928
|
79
|
16
|
0.20253164556962
|
0.0172413793103448
|
GO:BP
|
GO:1902533
|
positive regulation of intracellular signal transduction
|
5.25572943016904e-05
|
1037
|
134
|
23
|
0.171641791044776
|
0.0221793635486982
|
GO:BP
|
GO:0044419
|
biological process involved in interspecies interaction between organisms
|
5.2695755037533e-05
|
2255
|
75
|
25
|
0.333333333333333
|
0.0110864745011086
|
GO:BP
|
GO:0032623
|
interleukin-2 production
|
5.539507318295e-05
|
63
|
61
|
5
|
0.0819672131147541
|
0.0793650793650794
|
GO:BP
|
GO:0006954
|
inflammatory response
|
5.90234933970524e-05
|
794
|
82
|
15
|
0.182926829268293
|
0.0188916876574307
|
GO:BP
|
GO:0048519
|
negative regulation of biological process
|
6.06346896586213e-05
|
5757
|
83
|
47
|
0.566265060240964
|
0.00816397429216606
|
GO:BP
|
GO:0043029
|
T cell homeostasis
|
6.07868112816374e-05
|
40
|
99
|
5
|
0.0505050505050505
|
0.125
|
GO:BP
|
GO:0019885
|
antigen processing and presentation of endogenous peptide antigen via MHC class I
|
6.27620286046671e-05
|
13
|
144
|
4
|
0.0277777777777778
|
0.307692307692308
|
GO:BP
|
GO:0010628
|
positive regulation of gene expression
|
6.39154499348334e-05
|
1160
|
131
|
24
|
0.183206106870229
|
0.0206896551724138
|
GO:BP
|
GO:0060548
|
negative regulation of cell death
|
6.39944872973244e-05
|
1038
|
81
|
17
|
0.209876543209877
|
0.0163776493256262
|
GO:BP
|
GO:0002704
|
negative regulation of leukocyte mediated immunity
|
6.59948734606373e-05
|
51
|
79
|
5
|
0.0632911392405063
|
0.0980392156862745
|
GO:BP
|
GO:0002720
|
positive regulation of cytokine production involved in immune response
|
6.7456136112382e-05
|
54
|
75
|
5
|
0.0666666666666667
|
0.0925925925925926
|
GO:BP
|
GO:0043068
|
positive regulation of programmed cell death
|
7.61183942488198e-05
|
621
|
93
|
14
|
0.150537634408602
|
0.0225442834138486
|
GO:BP
|
GO:0031341
|
regulation of cell killing
|
8.44400031154507e-05
|
93
|
125
|
7
|
0.056
|
0.0752688172043011
|
GO:BP
|
GO:0009967
|
positive regulation of signal transduction
|
0.000105041818537132
|
1598
|
134
|
29
|
0.216417910447761
|
0.0181476846057572
|
GO:BP
|
GO:0007165
|
signal transduction
|
0.000120893952339069
|
6309
|
134
|
72
|
0.537313432835821
|
0.0114122681883024
|
GO:BP
|
GO:0050777
|
negative regulation of immune response
|
0.000125135880942232
|
157
|
79
|
7
|
0.0886075949367089
|
0.0445859872611465
|
GO:BP
|
GO:0002643
|
regulation of tolerance induction
|
0.000153111803595126
|
18
|
38
|
3
|
0.0789473684210526
|
0.166666666666667
|
GO:BP
|
GO:0007154
|
cell communication
|
0.000173770590561662
|
6829
|
99
|
59
|
0.595959595959596
|
0.00863962512813003
|
GO:BP
|
GO:0006950
|
response to stress
|
0.000175036201566825
|
4170
|
88
|
39
|
0.443181818181818
|
0.00935251798561151
|
GO:BP
|
GO:0042102
|
positive regulation of T cell proliferation
|
0.000206748493649087
|
104
|
85
|
6
|
0.0705882352941176
|
0.0576923076923077
|
GO:BP
|
GO:0032673
|
regulation of interleukin-4 production
|
0.000211011057172262
|
31
|
79
|
4
|
0.0506329113924051
|
0.129032258064516
|
GO:BP
|
GO:0010942
|
positive regulation of cell death
|
0.000213945971094675
|
684
|
93
|
14
|
0.150537634408602
|
0.0204678362573099
|
GO:BP
|
GO:1903038
|
negative regulation of leukocyte cell-cell adhesion
|
0.000216944976258164
|
142
|
133
|
8
|
0.0601503759398496
|
0.0563380281690141
|
GO:BP
|
GO:0032102
|
negative regulation of response to external stimulus
|
0.000222875478638531
|
406
|
79
|
10
|
0.126582278481013
|
0.0246305418719212
|
GO:BP
|
GO:0032649
|
regulation of interferon-gamma production
|
0.000224089019159194
|
110
|
82
|
6
|
0.0731707317073171
|
0.0545454545454545
|
GO:BP
|
GO:0032633
|
interleukin-4 production
|
0.000232346732017638
|
32
|
79
|
4
|
0.0506329113924051
|
0.125
|
GO:BP
|
GO:0051239
|
regulation of multicellular organismal process
|
0.00023328306587482
|
2861
|
82
|
29
|
0.353658536585366
|
0.0101363159734359
|
GO:BP
|
GO:0043066
|
negative regulation of apoptotic process
|
0.000254869318543931
|
921
|
81
|
15
|
0.185185185185185
|
0.0162866449511401
|
GO:BP
|
GO:0042130
|
negative regulation of T cell proliferation
|
0.000258815480922274
|
70
|
133
|
6
|
0.0451127819548872
|
0.0857142857142857
|
GO:BP
|
GO:0002483
|
antigen processing and presentation of endogenous peptide antigen
|
0.000277951358261361
|
19
|
144
|
4
|
0.0277777777777778
|
0.210526315789474
|
GO:BP
|
GO:0032609
|
interferon-gamma production
|
0.000277951358261361
|
115
|
82
|
6
|
0.0731707317073171
|
0.0521739130434783
|
GO:BP
|
GO:0050864
|
regulation of B cell activation
|
0.000288613811310015
|
194
|
134
|
9
|
0.0671641791044776
|
0.0463917525773196
|
GO:BP
|
GO:0031325
|
positive regulation of cellular metabolic process
|
0.000290786901123823
|
3274
|
135
|
45
|
0.333333333333333
|
0.0137446548564447
|
GO:BP
|
GO:0043069
|
negative regulation of programmed cell death
|
0.000324080754270497
|
943
|
81
|
15
|
0.185185185185185
|
0.0159066808059385
|
GO:BP
|
GO:0032101
|
regulation of response to external stimulus
|
0.000326523599769268
|
1051
|
82
|
16
|
0.195121951219512
|
0.0152235965746908
|
GO:BP
|
GO:0051173
|
positive regulation of nitrogen compound metabolic process
|
0.000337813248398415
|
3083
|
135
|
43
|
0.318518518518519
|
0.0139474537787869
|
GO:BP
|
GO:0023052
|
signaling
|
0.000341821697622503
|
6810
|
99
|
58
|
0.585858585858586
|
0.00851688693098385
|
GO:BP
|
GO:0002698
|
negative regulation of immune effector process
|
0.000342346667085087
|
125
|
79
|
6
|
0.0759493670886076
|
0.048
|
GO:BP
|
GO:0043122
|
regulation of I-kappaB kinase/NF-kappaB signaling
|
0.000342346667085087
|
251
|
134
|
10
|
0.0746268656716418
|
0.0398406374501992
|
GO:BP
|
GO:0032874
|
positive regulation of stress-activated MAPK cascade
|
0.000342346667085087
|
121
|
122
|
7
|
0.0573770491803279
|
0.0578512396694215
|
GO:BP
|
GO:0002366
|
leukocyte activation involved in immune response
|
0.00036606316044867
|
717
|
146
|
18
|
0.123287671232877
|
0.0251046025104603
|
GO:BP
|
GO:0050868
|
negative regulation of T cell activation
|
0.000369237042521582
|
123
|
24
|
4
|
0.166666666666667
|
0.032520325203252
|
GO:BP
|
GO:0009605
|
response to external stimulus
|
0.000369237042521582
|
2944
|
82
|
29
|
0.353658536585366
|
0.00985054347826087
|
GO:BP
|
GO:0070304
|
positive regulation of stress-activated protein kinase signaling cascade
|
0.000371788215841507
|
123
|
122
|
7
|
0.0573770491803279
|
0.0569105691056911
|
GO:BP
|
GO:0002260
|
lymphocyte homeostasis
|
0.000383830866485615
|
61
|
99
|
5
|
0.0505050505050505
|
0.0819672131147541
|
GO:BP
|
GO:0002263
|
cell activation involved in immune response
|
0.000383830866485615
|
721
|
146
|
18
|
0.123287671232877
|
0.0249653259361997
|
GO:BP
|
GO:0045953
|
negative regulation of natural killer cell mediated cytotoxicity
|
0.00038455575687877
|
16
|
62
|
3
|
0.0483870967741935
|
0.1875
|
GO:BP
|
GO:0048302
|
regulation of isotype switching to IgG isotypes
|
0.000408134320212241
|
13
|
79
|
3
|
0.0379746835443038
|
0.230769230769231
|
GO:BP
|
GO:0051247
|
positive regulation of protein metabolic process
|
0.000408134320212241
|
1564
|
133
|
27
|
0.203007518796992
|
0.0172634271099744
|
GO:BP
|
GO:0002204
|
somatic recombination of immunoglobulin genes involved in immune response
|
0.000409319025723695
|
48
|
129
|
5
|
0.0387596899224806
|
0.104166666666667
|
GO:BP
|
GO:0045190
|
isotype switching
|
0.000409319025723695
|
48
|
129
|
5
|
0.0387596899224806
|
0.104166666666667
|
GO:BP
|
GO:0002208
|
somatic diversification of immunoglobulins involved in immune response
|
0.000409319025723695
|
48
|
129
|
5
|
0.0387596899224806
|
0.104166666666667
|
GO:BP
|
GO:0032270
|
positive regulation of cellular protein metabolic process
|
0.00041769680989933
|
1477
|
133
|
26
|
0.195488721804511
|
0.017603249830738
|
GO:BP
|
GO:0051707
|
response to other organism
|
0.000431291609881066
|
1592
|
146
|
29
|
0.198630136986301
|
0.01821608040201
|
GO:BP
|
GO:0044068
|
modulation by symbiont of host cellular process
|
0.000433241870779983
|
25
|
125
|
4
|
0.032
|
0.16
|
GO:BP
|
GO:0043207
|
response to external biotic stimulus
|
0.000436552117391011
|
1594
|
146
|
29
|
0.198630136986301
|
0.0181932245922208
|
GO:BP
|
GO:0002716
|
negative regulation of natural killer cell mediated immunity
|
0.000440085618024642
|
17
|
62
|
3
|
0.0483870967741935
|
0.176470588235294
|
GO:BP
|
GO:0051716
|
cellular response to stimulus
|
0.000451863247821009
|
7781
|
99
|
63
|
0.636363636363636
|
0.00809664567536306
|
GO:BP
|
GO:0001913
|
T cell mediated cytotoxicity
|
0.000467060189794117
|
42
|
75
|
4
|
0.0533333333333333
|
0.0952380952380952
|
GO:BP
|
GO:0048291
|
isotype switching to IgG isotypes
|
0.000484334832409744
|
14
|
79
|
3
|
0.0379746835443038
|
0.214285714285714
|
GO:BP
|
GO:0001906
|
cell killing
|
0.000496782421128046
|
175
|
125
|
8
|
0.064
|
0.0457142857142857
|
GO:BP
|
GO:0098543
|
detection of other organism
|
0.000496782421128046
|
19
|
58
|
3
|
0.0517241379310345
|
0.157894736842105
|
GO:BP
|
GO:0052548
|
regulation of endopeptidase activity
|
0.000510559575763136
|
437
|
83
|
10
|
0.120481927710843
|
0.022883295194508
|
GO:BP
|
GO:0031343
|
positive regulation of cell killing
|
0.000510559575763136
|
59
|
111
|
5
|
0.045045045045045
|
0.0847457627118644
|
GO:BP
|
GO:0045582
|
positive regulation of T cell differentiation
|
0.000513304100896497
|
91
|
72
|
5
|
0.0694444444444444
|
0.0549450549450549
|
GO:BP
|
GO:0060333
|
interferon-gamma-mediated signaling pathway
|
0.000529447032901324
|
88
|
75
|
5
|
0.0666666666666667
|
0.0568181818181818
|
GO:BP
|
GO:0035556
|
intracellular signal transduction
|
0.000563420306086997
|
2772
|
134
|
39
|
0.291044776119403
|
0.0140692640692641
|
GO:BP
|
GO:0010647
|
positive regulation of cell communication
|
0.000565556724845055
|
1777
|
134
|
29
|
0.216417910447761
|
0.0163196398424311
|
GO:BP
|
GO:0051403
|
stress-activated MAPK cascade
|
0.000574359487988942
|
272
|
134
|
10
|
0.0746268656716418
|
0.0367647058823529
|
GO:BP
|
GO:0009607
|
response to biotic stimulus
|
0.000581278003892652
|
1626
|
146
|
29
|
0.198630136986301
|
0.0178351783517835
|
GO:BP
|
GO:0023056
|
positive regulation of signaling
|
0.000586438086503396
|
1782
|
134
|
29
|
0.216417910447761
|
0.0162738496071829
|
GO:BP
|
GO:0002381
|
immunoglobulin production involved in immunoglobulin-mediated immune response
|
0.00059566997627135
|
53
|
129
|
5
|
0.0387596899224806
|
0.0943396226415094
|
GO:BP
|
GO:1903708
|
positive regulation of hemopoiesis
|
0.000598701472310486
|
157
|
72
|
6
|
0.0833333333333333
|
0.0382165605095541
|
GO:BP
|
GO:1902107
|
positive regulation of leukocyte differentiation
|
0.000598701472310486
|
157
|
72
|
6
|
0.0833333333333333
|
0.0382165605095541
|
GO:BP
|
GO:0050672
|
negative regulation of lymphocyte proliferation
|
0.000603656309886335
|
85
|
133
|
6
|
0.0451127819548872
|
0.0705882352941176
|
GO:BP
|
GO:0048583
|
regulation of response to stimulus
|
0.000623242651791348
|
4278
|
82
|
36
|
0.439024390243902
|
0.00841514726507714
|
GO:BP
|
GO:0032501
|
multicellular organismal process
|
0.000623242651791348
|
7946
|
16
|
15
|
0.9375
|
0.00188774226025673
|
GO:BP
|
GO:0002889
|
regulation of immunoglobulin mediated immune response
|
0.000623242651791348
|
54
|
129
|
5
|
0.0387596899224806
|
0.0925925925925926
|
GO:BP
|
GO:0002712
|
regulation of B cell mediated immunity
|
0.000623242651791348
|
54
|
129
|
5
|
0.0387596899224806
|
0.0925925925925926
|
GO:BP
|
GO:0032945
|
negative regulation of mononuclear cell proliferation
|
0.000623242651791348
|
86
|
133
|
6
|
0.0451127819548872
|
0.0697674418604651
|
GO:BP
|
GO:0016447
|
somatic recombination of immunoglobulin gene segments
|
0.000623242651791348
|
54
|
129
|
5
|
0.0387596899224806
|
0.0925925925925926
|
GO:BP
|
GO:0032653
|
regulation of interleukin-10 production
|
0.000623242651791348
|
60
|
58
|
4
|
0.0689655172413793
|
0.0666666666666667
|
GO:BP
|
GO:0043280
|
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
0.000623844392961251
|
138
|
83
|
6
|
0.072289156626506
|
0.0434782608695652
|
GO:BP
|
GO:0001911
|
negative regulation of leukocyte mediated cytotoxicity
|
0.000634285067233309
|
20
|
62
|
3
|
0.0483870967741935
|
0.15
|
GO:BP
|
GO:0051240
|
positive regulation of multicellular organismal process
|
0.000635759489893647
|
1455
|
10
|
6
|
0.6
|
0.00412371134020619
|
GO:BP
|
GO:0032872
|
regulation of stress-activated MAPK cascade
|
0.00066041178862005
|
190
|
122
|
8
|
0.0655737704918033
|
0.0421052631578947
|
GO:BP
|
GO:0032613
|
interleukin-10 production
|
0.000688107607322322
|
62
|
58
|
4
|
0.0689655172413793
|
0.0645161290322581
|
GO:BP
|
GO:0070302
|
regulation of stress-activated protein kinase signaling cascade
|
0.000729336828786827
|
193
|
122
|
8
|
0.0655737704918033
|
0.0414507772020725
|
GO:BP
|
GO:0051250
|
negative regulation of lymphocyte activation
|
0.000729336828786827
|
156
|
24
|
4
|
0.166666666666667
|
0.0256410256410256
|
GO:BP
|
GO:0019883
|
antigen processing and presentation of endogenous antigen
|
0.000737836481105743
|
26
|
144
|
4
|
0.0277777777777778
|
0.153846153846154
|
GO:BP
|
GO:0001909
|
leukocyte mediated cytotoxicity
|
0.000742468928873071
|
107
|
111
|
6
|
0.0540540540540541
|
0.0560747663551402
|
GO:BP
|
GO:0019222
|
regulation of metabolic process
|
0.000770623502252762
|
7148
|
135
|
76
|
0.562962962962963
|
0.0106323447118075
|
GO:BP
|
GO:0052547
|
regulation of peptidase activity
|
0.000774750317115152
|
467
|
83
|
10
|
0.120481927710843
|
0.0214132762312634
|
GO:BP
|
GO:0031098
|
stress-activated protein kinase signaling cascade
|
0.00081960458677448
|
288
|
134
|
10
|
0.0746268656716418
|
0.0347222222222222
|
GO:BP
|
GO:0045862
|
positive regulation of proteolysis
|
0.000825119262608289
|
378
|
83
|
9
|
0.108433734939759
|
0.0238095238095238
|
GO:BP
|
GO:0060255
|
regulation of macromolecule metabolic process
|
0.000825119262608289
|
6603
|
83
|
48
|
0.578313253012048
|
0.0072694229895502
|
GO:BP
|
GO:0045621
|
positive regulation of lymphocyte differentiation
|
0.000830959712378312
|
104
|
72
|
5
|
0.0694444444444444
|
0.0480769230769231
|
GO:BP
|
GO:0070664
|
negative regulation of leukocyte proliferation
|
0.000842695065550685
|
92
|
133
|
6
|
0.0451127819548872
|
0.0652173913043478
|
GO:BP
|
GO:0098581
|
detection of external biotic stimulus
|
0.000844338442905979
|
24
|
58
|
3
|
0.0517241379310345
|
0.125
|
GO:BP
|
GO:0043065
|
positive regulation of apoptotic process
|
0.000844338442905979
|
604
|
93
|
12
|
0.129032258064516
|
0.0198675496688742
|
GO:BP
|
GO:0050852
|
T cell receptor signaling pathway
|
0.000855013358243831
|
203
|
61
|
6
|
0.0983606557377049
|
0.0295566502463054
|
GO:BP
|
GO:0007249
|
I-kappaB kinase/NF-kappaB signaling
|
0.000862381148244111
|
291
|
134
|
10
|
0.0746268656716418
|
0.0343642611683849
|
GO:BP
|
GO:2000026
|
regulation of multicellular organismal development
|
0.000920351503008077
|
1447
|
82
|
18
|
0.219512195121951
|
0.0124395300621977
|
GO:BP
|
GO:0042832
|
defense response to protozoan
|
0.000940646930984646
|
25
|
58
|
3
|
0.0517241379310345
|
0.12
|
GO:BP
|
GO:0032753
|
positive regulation of interleukin-4 production
|
0.000960998738254379
|
24
|
61
|
3
|
0.0491803278688525
|
0.125
|
GO:BP
|
GO:0016445
|
somatic diversification of immunoglobulins
|
0.00100032492506582
|
61
|
129
|
5
|
0.0387596899224806
|
0.0819672131147541
|
GO:BP
|
GO:0031342
|
negative regulation of cell killing
|
0.00100032492506582
|
24
|
62
|
3
|
0.0483870967741935
|
0.125
|
GO:BP
|
GO:0065009
|
regulation of molecular function
|
0.00102142046046262
|
3221
|
133
|
42
|
0.315789473684211
|
0.0130394287488358
|
GO:BP
|
GO:0042127
|
regulation of cell population proliferation
|
0.00102142046046262
|
1774
|
133
|
28
|
0.210526315789474
|
0.0157835400225479
|
GO:BP
|
GO:0002320
|
lymphoid progenitor cell differentiation
|
0.00102142046046262
|
21
|
72
|
3
|
0.0416666666666667
|
0.142857142857143
|
GO:BP
|
GO:2001056
|
positive regulation of cysteine-type endopeptidase activity
|
0.00102142046046262
|
154
|
83
|
6
|
0.072289156626506
|
0.038961038961039
|
GO:BP
|
GO:0001562
|
response to protozoan
|
0.00102526301664327
|
26
|
58
|
3
|
0.0517241379310345
|
0.115384615384615
|
GO:BP
|
GO:0009615
|
response to virus
|
0.00105701527630319
|
364
|
23
|
5
|
0.217391304347826
|
0.0137362637362637
|
GO:BP
|
GO:0051246
|
regulation of protein metabolic process
|
0.00116323799787104
|
2704
|
133
|
37
|
0.278195488721804
|
0.0136834319526627
|
GO:BP
|
GO:0001910
|
regulation of leukocyte mediated cytotoxicity
|
0.00117628248440001
|
74
|
111
|
5
|
0.045045045045045
|
0.0675675675675676
|
GO:BP
|
GO:0002562
|
somatic diversification of immune receptors via germline recombination within a single locus
|
0.00118098097677476
|
64
|
129
|
5
|
0.0387596899224806
|
0.078125
|
GO:BP
|
GO:0048872
|
homeostasis of number of cells
|
0.00118098097677476
|
261
|
99
|
8
|
0.0808080808080808
|
0.0306513409961686
|
GO:BP
|
GO:0016444
|
somatic cell DNA recombination
|
0.00118098097677476
|
64
|
129
|
5
|
0.0387596899224806
|
0.078125
|
GO:BP
|
GO:0019724
|
B cell mediated immunity
|
0.00118146429157375
|
226
|
85
|
7
|
0.0823529411764706
|
0.0309734513274336
|
GO:BP
|
GO:0022408
|
negative regulation of cell-cell adhesion
|
0.00118934860620603
|
194
|
133
|
8
|
0.0601503759398496
|
0.0412371134020619
|
GO:BP
|
GO:0050728
|
negative regulation of inflammatory response
|
0.00128330501685421
|
171
|
79
|
6
|
0.0759493670886076
|
0.0350877192982456
|
GO:BP
|
GO:0002695
|
negative regulation of leukocyte activation
|
0.00128330501685421
|
188
|
24
|
4
|
0.166666666666667
|
0.0212765957446809
|
GO:BP
|
GO:0050851
|
antigen receptor-mediated signaling pathway
|
0.00128708885743831
|
323
|
61
|
7
|
0.114754098360656
|
0.021671826625387
|
GO:BP
|
GO:0045191
|
regulation of isotype switching
|
0.00134401553199469
|
35
|
129
|
4
|
0.0310077519379845
|
0.114285714285714
|
GO:BP
|
GO:0001776
|
leukocyte homeostasis
|
0.00134401553199469
|
86
|
99
|
5
|
0.0505050505050505
|
0.0581395348837209
|
GO:BP
|
GO:0048585
|
negative regulation of response to stimulus
|
0.00134401553199469
|
1733
|
91
|
21
|
0.230769230769231
|
0.0121177149451818
|
GO:BP
|
GO:0042269
|
regulation of natural killer cell mediated cytotoxicity
|
0.00140244402228999
|
41
|
111
|
4
|
0.036036036036036
|
0.0975609756097561
|
GO:BP
|
GO:0002637
|
regulation of immunoglobulin production
|
0.00141362759697632
|
67
|
129
|
5
|
0.0387596899224806
|
0.0746268656716418
|
GO:BP
|
GO:0032268
|
regulation of cellular protein metabolic process
|
0.00145097894849972
|
2541
|
83
|
25
|
0.301204819277108
|
0.00983864620228257
|
GO:BP
|
GO:0032743
|
positive regulation of interleukin-2 production
|
0.00176613167148539
|
32
|
58
|
3
|
0.0517241379310345
|
0.09375
|
GO:BP
|
GO:0044003
|
modulation by symbiont of host process
|
0.00179298437410694
|
39
|
125
|
4
|
0.032
|
0.102564102564103
|
GO:BP
|
GO:0030330
|
DNA damage response, signal transduction by p53 class mediator
|
0.00181882239325737
|
110
|
83
|
5
|
0.0602409638554217
|
0.0454545454545455
|
GO:BP
|
GO:0050866
|
negative regulation of cell activation
|
0.00190388711165653
|
211
|
24
|
4
|
0.166666666666667
|
0.018957345971564
|
GO:BP
|
GO:0002200
|
somatic diversification of immune receptors
|
0.00193810666958786
|
72
|
129
|
5
|
0.0387596899224806
|
0.0694444444444444
|
GO:BP
|
GO:0002715
|
regulation of natural killer cell mediated immunity
|
0.00195635850292044
|
45
|
111
|
4
|
0.036036036036036
|
0.0888888888888889
|
GO:BP
|
GO:0001916
|
positive regulation of T cell mediated cytotoxicity
|
0.00196788935872484
|
26
|
75
|
3
|
0.04
|
0.115384615384615
|
GO:BP
|
GO:0051709
|
regulation of killing of cells of other organism
|
0.00199270602448254
|
16
|
125
|
3
|
0.024
|
0.1875
|
GO:BP
|
GO:0046631
|
alpha-beta T cell activation
|
0.00205142818568936
|
155
|
61
|
5
|
0.0819672131147541
|
0.032258064516129
|
GO:BP
|
GO:0044093
|
positive regulation of molecular function
|
0.00217364474852763
|
1771
|
133
|
27
|
0.203007518796992
|
0.0152456239412761
|
GO:BP
|
GO:1903317
|
regulation of protein maturation
|
0.00221052803544889
|
68
|
76
|
4
|
0.0526315789473684
|
0.0588235294117647
|
GO:BP
|
GO:0002683
|
negative regulation of immune system process
|
0.0022382622415848
|
420
|
24
|
5
|
0.208333333333333
|
0.0119047619047619
|
GO:BP
|
GO:0050778
|
positive regulation of immune response
|
0.00234929927863134
|
753
|
111
|
14
|
0.126126126126126
|
0.0185922974767596
|
GO:BP
|
GO:0009595
|
detection of biotic stimulus
|
0.00235624763664325
|
36
|
58
|
3
|
0.0517241379310345
|
0.0833333333333333
|
GO:BP
|
GO:0002437
|
inflammatory response to antigenic stimulus
|
0.00243533507293288
|
65
|
82
|
4
|
0.0487804878048781
|
0.0615384615384615
|
GO:BP
|
GO:0044403
|
biological process involved in symbiotic interaction
|
0.00243648035039794
|
1001
|
75
|
13
|
0.173333333333333
|
0.012987012987013
|
GO:BP
|
GO:0010950
|
positive regulation of endopeptidase activity
|
0.00246368168178236
|
187
|
83
|
6
|
0.072289156626506
|
0.0320855614973262
|
GO:BP
|
GO:0032729
|
positive regulation of interferon-gamma production
|
0.00255609317541805
|
66
|
82
|
4
|
0.0487804878048781
|
0.0606060606060606
|
GO:BP
|
GO:0050690
|
regulation of defense response to virus by virus
|
0.00258610136477423
|
29
|
75
|
3
|
0.04
|
0.103448275862069
|
GO:BP
|
GO:0097191
|
extrinsic apoptotic signaling pathway
|
0.00258813350172206
|
223
|
132
|
8
|
0.0606060606060606
|
0.0358744394618834
|
GO:BP
|
GO:0008283
|
cell population proliferation
|
0.00265688013317461
|
2054
|
142
|
31
|
0.21830985915493
|
0.0150925024342746
|
GO:BP
|
GO:0032733
|
positive regulation of interleukin-10 production
|
0.00269379845488339
|
38
|
58
|
3
|
0.0517241379310345
|
0.0789473684210526
|
GO:BP
|
GO:0002312
|
B cell activation involved in immune response
|
0.00277038584064811
|
79
|
129
|
5
|
0.0387596899224806
|
0.0632911392405063
|
GO:BP
|
GO:0001818
|
negative regulation of cytokine production
|
0.00278273483168882
|
381
|
79
|
8
|
0.10126582278481
|
0.020997375328084
|
GO:BP
|
GO:0001912
|
positive regulation of leukocyte mediated cytotoxicity
|
0.00293607821454414
|
51
|
111
|
4
|
0.036036036036036
|
0.0784313725490196
|
GO:BP
|
GO:0033077
|
T cell differentiation in thymus
|
0.00303769499812909
|
76
|
75
|
4
|
0.0533333333333333
|
0.0526315789473684
|
GO:BP
|
GO:0046330
|
positive regulation of JNK cascade
|
0.00311503469543809
|
86
|
122
|
5
|
0.040983606557377
|
0.0581395348837209
|
GO:BP
|
GO:1903318
|
negative regulation of protein maturation
|
0.00314417869565094
|
31
|
76
|
3
|
0.0394736842105263
|
0.0967741935483871
|
GO:BP
|
GO:0010955
|
negative regulation of protein processing
|
0.00314417869565094
|
31
|
76
|
3
|
0.0394736842105263
|
0.0967741935483871
|
GO:BP
|
GO:0010468
|
regulation of gene expression
|
0.00320394723881897
|
5196
|
83
|
39
|
0.469879518072289
|
0.00750577367205543
|
GO:BP
|
GO:0002479
|
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
|
0.00345815631906677
|
75
|
144
|
5
|
0.0347222222222222
|
0.0666666666666667
|
GO:BP
|
GO:0097190
|
apoptotic signaling pathway
|
0.00347446445910535
|
600
|
96
|
11
|
0.114583333333333
|
0.0183333333333333
|
GO:BP
|
GO:2000758
|
positive regulation of peptidyl-lysine acetylation
|
0.00347446445910535
|
34
|
72
|
3
|
0.0416666666666667
|
0.0882352941176471
|
GO:BP
|
GO:0098542
|
defense response to other organism
|
0.00348222694301524
|
1218
|
82
|
15
|
0.182926829268293
|
0.0123152709359606
|
GO:BP
|
GO:0010952
|
positive regulation of peptidase activity
|
0.00372954375447321
|
205
|
83
|
6
|
0.072289156626506
|
0.0292682926829268
|
GO:BP
|
GO:0006508
|
proteolysis
|
0.00391644919266951
|
1836
|
134
|
27
|
0.201492537313433
|
0.0147058823529412
|
GO:BP
|
GO:0050896
|
response to stimulus
|
0.00391644919266951
|
9407
|
100
|
69
|
0.69
|
0.00733496332518337
|
GO:BP
|
GO:0046634
|
regulation of alpha-beta T cell activation
|
0.00393197407232996
|
102
|
61
|
4
|
0.0655737704918033
|
0.0392156862745098
|
GO:BP
|
GO:0042770
|
signal transduction in response to DNA damage
|
0.00393197407232996
|
135
|
83
|
5
|
0.0602409638554217
|
0.037037037037037
|
GO:BP
|
GO:0002832
|
negative regulation of response to biotic stimulus
|
0.00393197407232996
|
100
|
62
|
4
|
0.0645161290322581
|
0.04
|
GO:BP
|
GO:0032675
|
regulation of interleukin-6 production
|
0.00395464268787652
|
168
|
67
|
5
|
0.0746268656716418
|
0.0297619047619048
|
GO:BP
|
GO:0001914
|
regulation of T cell mediated cytotoxicity
|
0.00406723642474909
|
35
|
75
|
3
|
0.04
|
0.0857142857142857
|
GO:BP
|
GO:0140352
|
export from cell
|
0.00406723642474909
|
1418
|
146
|
24
|
0.164383561643836
|
0.0169252468265162
|
GO:BP
|
GO:0045595
|
regulation of cell differentiation
|
0.0042567390231997
|
1679
|
82
|
18
|
0.219512195121951
|
0.0107206670637284
|
GO:BP
|
GO:0050869
|
negative regulation of B cell activation
|
0.00429955054703439
|
34
|
79
|
3
|
0.0379746835443038
|
0.0882352941176471
|
GO:BP
|
GO:0032635
|
interleukin-6 production
|
0.00430863470397269
|
172
|
67
|
5
|
0.0746268656716418
|
0.0290697674418605
|
GO:BP
|
GO:1990830
|
cellular response to leukemia inhibitory factor
|
0.00430863470397269
|
89
|
129
|
5
|
0.0387596899224806
|
0.0561797752808989
|
GO:BP
|
GO:0042590
|
antigen processing and presentation of exogenous peptide antigen via MHC class I
|
0.0043339946844524
|
80
|
144
|
5
|
0.0347222222222222
|
0.0625
|
GO:BP
|
GO:0032502
|
developmental process
|
0.00434637122440662
|
6628
|
18
|
14
|
0.777777777777778
|
0.00211225105612553
|
GO:BP
|
GO:0043123
|
positive regulation of I-kappaB kinase/NF-kappaB signaling
|
0.00444200698660928
|
185
|
134
|
7
|
0.0522388059701493
|
0.0378378378378378
|
GO:BP
|
GO:0016032
|
viral process
|
0.00445379173379489
|
942
|
75
|
12
|
0.16
|
0.0127388535031847
|
GO:BP
|
GO:1990823
|
response to leukemia inhibitory factor
|
0.00445379173379489
|
90
|
129
|
5
|
0.0387596899224806
|
0.0555555555555556
|
GO:BP
|
GO:0008285
|
negative regulation of cell population proliferation
|
0.00454510600559585
|
790
|
142
|
16
|
0.112676056338028
|
0.020253164556962
|
GO:BP
|
GO:0043154
|
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
0.00455768099494684
|
81
|
81
|
4
|
0.0493827160493827
|
0.0493827160493827
|
GO:BP
|
GO:0016064
|
immunoglobulin mediated immune response
|
0.00494494692159013
|
223
|
82
|
6
|
0.0731707317073171
|
0.0269058295964126
|
GO:BP
|
GO:0071346
|
cellular response to interferon-gamma
|
0.00512322367554223
|
175
|
146
|
7
|
0.0479452054794521
|
0.04
|
GO:BP
|
GO:0031295
|
T cell costimulation
|
0.00512322367554223
|
58
|
50
|
3
|
0.06
|
0.0517241379310345
|
GO:BP
|
GO:0042092
|
type 2 immune response
|
0.00515969860303758
|
37
|
79
|
3
|
0.0379746835443038
|
0.0810810810810811
|
GO:BP
|
GO:0006919
|
activation of cysteine-type endopeptidase activity involved in apoptotic process
|
0.00520321229921072
|
92
|
132
|
5
|
0.0378787878787879
|
0.0543478260869565
|
GO:BP
|
GO:0042267
|
natural killer cell mediated cytotoxicity
|
0.0052137483898964
|
62
|
111
|
4
|
0.036036036036036
|
0.0645161290322581
|
GO:BP
|
GO:0032940
|
secretion by cell
|
0.00523773839873272
|
1364
|
146
|
23
|
0.157534246575342
|
0.0168621700879765
|
GO:BP
|
GO:0032879
|
regulation of localization
|
0.00543005259811829
|
2872
|
142
|
38
|
0.267605633802817
|
0.0132311977715877
|
GO:BP
|
GO:0031294
|
lymphocyte costimulation
|
0.00546815325278599
|
60
|
50
|
3
|
0.06
|
0.05
|
GO:BP
|
GO:0008284
|
positive regulation of cell population proliferation
|
0.00558772409642439
|
982
|
85
|
13
|
0.152941176470588
|
0.0132382892057026
|
GO:BP
|
GO:0007162
|
negative regulation of cell adhesion
|
0.00560487957777656
|
304
|
24
|
4
|
0.166666666666667
|
0.0131578947368421
|
GO:BP
|
GO:0050794
|
regulation of cellular process
|
0.00583708934707575
|
11473
|
99
|
78
|
0.787878787878788
|
0.00679857055695982
|
GO:BP
|
GO:2000117
|
negative regulation of cysteine-type endopeptidase activity
|
0.00592004788715165
|
89
|
81
|
4
|
0.0493827160493827
|
0.0449438202247191
|
GO:BP
|
GO:0002228
|
natural killer cell mediated immunity
|
0.00592004788715165
|
65
|
111
|
4
|
0.036036036036036
|
0.0615384615384615
|
GO:BP
|
GO:0048731
|
system development
|
0.00601914914108526
|
5052
|
18
|
12
|
0.666666666666667
|
0.00237529691211401
|
GO:BP
|
GO:0042100
|
B cell proliferation
|
0.00626815690144557
|
98
|
131
|
5
|
0.0381679389312977
|
0.0510204081632653
|
GO:BP
|
GO:1901985
|
positive regulation of protein acetylation
|
0.00690002481805622
|
46
|
72
|
3
|
0.0416666666666667
|
0.0652173913043478
|
GO:BP
|
GO:0046635
|
positive regulation of alpha-beta T cell activation
|
0.00712493011142985
|
67
|
50
|
3
|
0.06
|
0.0447761194029851
|
GO:BP
|
GO:0031401
|
positive regulation of protein modification process
|
0.00736593770405563
|
1074
|
133
|
18
|
0.135338345864662
|
0.0167597765363128
|
GO:BP
|
GO:0010951
|
negative regulation of endopeptidase activity
|
0.00738344378784474
|
253
|
14
|
3
|
0.214285714285714
|
0.0118577075098814
|
GO:BP
|
GO:0044267
|
cellular protein metabolic process
|
0.00752049833521953
|
5229
|
134
|
56
|
0.417910447761194
|
0.0107095046854083
|
GO:BP
|
GO:0050871
|
positive regulation of B cell activation
|
0.0075839879516132
|
151
|
134
|
6
|
0.0447761194029851
|
0.0397350993377483
|
GO:BP
|
GO:0046903
|
secretion
|
0.00759059506548417
|
1501
|
146
|
24
|
0.164383561643836
|
0.0159893404397069
|
GO:BP
|
GO:1902531
|
regulation of intracellular signal transduction
|
0.00759361726607923
|
1842
|
134
|
26
|
0.194029850746269
|
0.0141150922909881
|
GO:BP
|
GO:0048856
|
anatomical structure development
|
0.00789794279637682
|
6106
|
18
|
13
|
0.722222222222222
|
0.00212905339010809
|
GO:BP
|
GO:0050793
|
regulation of developmental process
|
0.0079033354199806
|
2605
|
82
|
23
|
0.280487804878049
|
0.00882917466410749
|
GO:BP
|
GO:0006887
|
exocytosis
|
0.00815104434406217
|
904
|
146
|
17
|
0.116438356164384
|
0.0188053097345133
|
GO:BP
|
GO:0002274
|
myeloid leukocyte activation
|
0.00825942061589515
|
667
|
146
|
14
|
0.0958904109589041
|
0.0209895052473763
|
GO:BP
|
GO:0010466
|
negative regulation of peptidase activity
|
0.00836141937025822
|
267
|
14
|
3
|
0.214285714285714
|
0.0112359550561798
|
GO:BP
|
GO:0051701
|
biological process involved in interaction with host
|
0.00845805679774755
|
221
|
129
|
7
|
0.0542635658914729
|
0.0316742081447964
|
GO:BP
|
GO:0034341
|
response to interferon-gamma
|
0.00861895160115865
|
196
|
146
|
7
|
0.0479452054794521
|
0.0357142857142857
|
GO:BP
|
GO:0002757
|
immune response-activating signal transduction
|
0.0086237321598098
|
477
|
61
|
7
|
0.114754098360656
|
0.0146750524109015
|
GO:BP
|
GO:0002429
|
immune response-activating cell surface receptor signaling pathway
|
0.0086237321598098
|
477
|
61
|
7
|
0.114754098360656
|
0.0146750524109015
|
GO:BP
|
GO:0030888
|
regulation of B cell proliferation
|
0.00888820065786979
|
63
|
131
|
4
|
0.0305343511450382
|
0.0634920634920635
|
GO:BP
|
GO:0045861
|
negative regulation of proteolysis
|
0.00888820065786979
|
359
|
81
|
7
|
0.0864197530864197
|
0.0194986072423398
|
GO:BP
|
GO:0002474
|
antigen processing and presentation of peptide antigen via MHC class I
|
0.00916260816645849
|
99
|
144
|
5
|
0.0347222222222222
|
0.0505050505050505
|
GO:BP
|
GO:0002831
|
regulation of response to biotic stimulus
|
0.00981526825738633
|
415
|
10
|
3
|
0.3
|
0.0072289156626506
|
GO:BP
|
GO:0071479
|
cellular response to ionizing radiation
|
0.0101098403104712
|
69
|
125
|
4
|
0.032
|
0.0579710144927536
|
GO:BP
|
GO:0031571
|
mitotic G1 DNA damage checkpoint
|
0.0104220947409477
|
66
|
132
|
4
|
0.0303030303030303
|
0.0606060606060606
|
GO:BP
|
GO:0060337
|
type I interferon signaling pathway
|
0.0105054693812582
|
95
|
42
|
3
|
0.0714285714285714
|
0.0315789473684211
|
GO:BP
|
GO:0071357
|
cellular response to type I interferon
|
0.0108011112618329
|
96
|
42
|
3
|
0.0714285714285714
|
0.03125
|
GO:BP
|
GO:0042093
|
T-helper cell differentiation
|
0.0108074095067689
|
66
|
61
|
3
|
0.0491803278688525
|
0.0454545454545455
|
GO:BP
|
GO:0044783
|
G1 DNA damage checkpoint
|
0.0108224008343676
|
67
|
132
|
4
|
0.0303030303030303
|
0.0597014925373134
|
GO:BP
|
GO:0051241
|
negative regulation of multicellular organismal process
|
0.0108224008343676
|
1160
|
79
|
13
|
0.164556962025316
|
0.0112068965517241
|
GO:BP
|
GO:0002285
|
lymphocyte activation involved in immune response
|
0.0108224008343676
|
190
|
79
|
5
|
0.0632911392405063
|
0.0263157894736842
|
GO:BP
|
GO:0044819
|
mitotic G1/S transition checkpoint
|
0.0108224008343676
|
67
|
132
|
4
|
0.0303030303030303
|
0.0597014925373134
|
GO:BP
|
GO:0045824
|
negative regulation of innate immune response
|
0.0111680020155367
|
66
|
62
|
3
|
0.0483870967741935
|
0.0454545454545455
|
GO:BP
|
GO:0002294
|
CD4-positive, alpha-beta T cell differentiation involved in immune response
|
0.0115058942183828
|
68
|
61
|
3
|
0.0491803278688525
|
0.0441176470588235
|
GO:BP
|
GO:0002768
|
immune response-regulating cell surface receptor signaling pathway
|
0.0118760316302295
|
512
|
61
|
7
|
0.114754098360656
|
0.013671875
|
GO:BP
|
GO:0002293
|
alpha-beta T cell differentiation involved in immune response
|
0.0119170856425467
|
69
|
61
|
3
|
0.0491803278688525
|
0.0434782608695652
|
GO:BP
|
GO:0002287
|
alpha-beta T cell activation involved in immune response
|
0.0119170856425467
|
69
|
61
|
3
|
0.0491803278688525
|
0.0434782608695652
|
GO:BP
|
GO:0034340
|
response to type I interferon
|
0.012028687673975
|
101
|
42
|
3
|
0.0714285714285714
|
0.0297029702970297
|
GO:BP
|
GO:0002764
|
immune response-regulating signaling pathway
|
0.0120543898257879
|
515
|
61
|
7
|
0.114754098360656
|
0.0135922330097087
|
GO:BP
|
GO:1901700
|
response to oxygen-containing compound
|
0.0122850958687962
|
1739
|
140
|
25
|
0.178571428571429
|
0.0143760782058654
|
GO:BP
|
GO:0051254
|
positive regulation of RNA metabolic process
|
0.0123053708154716
|
1714
|
142
|
25
|
0.176056338028169
|
0.014585764294049
|
GO:BP
|
GO:0051090
|
regulation of DNA-binding transcription factor activity
|
0.0125468917985425
|
456
|
131
|
10
|
0.0763358778625954
|
0.0219298245614035
|
GO:BP
|
GO:0032269
|
negative regulation of cellular protein metabolic process
|
0.012821855663519
|
1082
|
97
|
14
|
0.144329896907216
|
0.0129390018484288
|
GO:BP
|
GO:0050789
|
regulation of biological process
|
0.01288523659218
|
12091
|
27
|
25
|
0.925925925925926
|
0.00206765362666446
|
GO:BP
|
GO:0035821
|
modulation of process of other organism
|
0.0130617304602352
|
128
|
74
|
4
|
0.0540540540540541
|
0.03125
|
GO:BP
|
GO:0042401
|
cellular biogenic amine biosynthetic process
|
0.013431998316903
|
38
|
118
|
3
|
0.0254237288135593
|
0.0789473684210526
|
GO:BP
|
GO:0007275
|
multicellular organism development
|
0.0135394799116344
|
5613
|
18
|
12
|
0.666666666666667
|
0.00213789417423838
|
GO:BP
|
GO:2000756
|
regulation of peptidyl-lysine acetylation
|
0.0137896976750248
|
63
|
72
|
3
|
0.0416666666666667
|
0.0476190476190476
|
GO:BP
|
GO:0003170
|
heart valve development
|
0.0137896976750248
|
63
|
72
|
3
|
0.0416666666666667
|
0.0476190476190476
|
GO:BP
|
GO:0046328
|
regulation of JNK cascade
|
0.0140994154455485
|
133
|
122
|
5
|
0.040983606557377
|
0.037593984962406
|
GO:BP
|
GO:0009309
|
amine biosynthetic process
|
0.014140861498942
|
39
|
118
|
3
|
0.0254237288135593
|
0.0769230769230769
|
GO:BP
|
GO:0032509
|
endosome transport via multivesicular body sorting pathway
|
0.0145021611174894
|
34
|
137
|
3
|
0.0218978102189781
|
0.0882352941176471
|
GO:BP
|
GO:0000041
|
transition metal ion transport
|
0.0154444496866174
|
129
|
129
|
5
|
0.0387596899224806
|
0.0387596899224806
|
GO:BP
|
GO:0031323
|
regulation of cellular metabolic process
|
0.0161308034626505
|
6269
|
135
|
63
|
0.466666666666667
|
0.0100494496729941
|
GO:BP
|
GO:2000134
|
negative regulation of G1/S transition of mitotic cell cycle
|
0.0162870036018548
|
128
|
132
|
5
|
0.0378787878787879
|
0.0390625
|
GO:BP
|
GO:0002714
|
positive regulation of B cell mediated immunity
|
0.0163079981178638
|
38
|
129
|
3
|
0.0232558139534884
|
0.0789473684210526
|
GO:BP
|
GO:0002891
|
positive regulation of immunoglobulin mediated immune response
|
0.0163079981178638
|
38
|
129
|
3
|
0.0232558139534884
|
0.0789473684210526
|
GO:BP
|
GO:2001235
|
positive regulation of apoptotic signaling pathway
|
0.0165919714684312
|
129
|
132
|
5
|
0.0378787878787879
|
0.0387596899224806
|
GO:BP
|
GO:0006826
|
iron ion transport
|
0.0165972270932176
|
80
|
129
|
4
|
0.0310077519379845
|
0.05
|
GO:BP
|
GO:0070613
|
regulation of protein processing
|
0.0172644035268137
|
66
|
76
|
3
|
0.0394736842105263
|
0.0454545454545455
|
GO:BP
|
GO:0002253
|
activation of immune response
|
0.018400636126808
|
568
|
61
|
7
|
0.114754098360656
|
0.0123239436619718
|
GO:BP
|
GO:0001959
|
regulation of cytokine-mediated signaling pathway
|
0.0187857382074816
|
184
|
96
|
5
|
0.0520833333333333
|
0.0271739130434783
|
GO:BP
|
GO:0080135
|
regulation of cellular response to stress
|
0.0187857382074816
|
725
|
75
|
9
|
0.12
|
0.0124137931034483
|
GO:BP
|
GO:1902807
|
negative regulation of cell cycle G1/S phase transition
|
0.0189543693674298
|
134
|
132
|
5
|
0.0378787878787879
|
0.0373134328358209
|
GO:BP
|
GO:0051172
|
negative regulation of nitrogen compound metabolic process
|
0.0189604540714898
|
2518
|
97
|
24
|
0.247422680412371
|
0.00953137410643368
|
GO:BP
|
GO:0045935
|
positive regulation of nucleobase-containing compound metabolic process
|
0.0190845609309035
|
1887
|
142
|
26
|
0.183098591549296
|
0.0137784843667197
|
GO:BP
|
GO:0019058
|
viral life cycle
|
0.0193074915310533
|
353
|
51
|
5
|
0.0980392156862745
|
0.0141643059490085
|
GO:BP
|
GO:0055076
|
transition metal ion homeostasis
|
0.0193105555504428
|
138
|
129
|
5
|
0.0387596899224806
|
0.036231884057971
|
GO:BP
|
GO:1901224
|
positive regulation of NIK/NF-kappaB signaling
|
0.0195962350866023
|
68
|
78
|
3
|
0.0384615384615385
|
0.0441176470588235
|
GO:BP
|
GO:0008625
|
extrinsic apoptotic signaling pathway via death domain receptors
|
0.0197196076473895
|
83
|
132
|
4
|
0.0303030303030303
|
0.0481927710843374
|
GO:BP
|
GO:0044092
|
negative regulation of molecular function
|
0.0197449892360663
|
1219
|
16
|
5
|
0.3125
|
0.00410172272354389
|
GO:BP
|
GO:0051248
|
negative regulation of protein metabolic process
|
0.0197449892360663
|
1151
|
97
|
14
|
0.144329896907216
|
0.0121633362293658
|
GO:BP
|
GO:0048513
|
animal organ development
|
0.0201830023725272
|
3672
|
9
|
6
|
0.666666666666667
|
0.00163398692810458
|
GO:BP
|
GO:0055072
|
iron ion homeostasis
|
0.0202914662117697
|
86
|
129
|
4
|
0.0310077519379845
|
0.0465116279069767
|
GO:BP
|
GO:0071985
|
multivesicular body sorting pathway
|
0.0204902587147546
|
40
|
137
|
3
|
0.0218978102189781
|
0.075
|
GO:BP
|
GO:0009966
|
regulation of signal transduction
|
0.020669505565951
|
3165
|
137
|
37
|
0.27007299270073
|
0.0116903633491311
|
GO:BP
|
GO:0009617
|
response to bacterium
|
0.0206964624744954
|
743
|
134
|
13
|
0.0970149253731343
|
0.0174966352624495
|
GO:BP
|
GO:0051171
|
regulation of nitrogen compound metabolic process
|
0.0206964624744954
|
5848
|
135
|
59
|
0.437037037037037
|
0.0100889192886457
|
GO:BP
|
GO:1903322
|
positive regulation of protein modification by small protein conjugation or removal
|
0.0208282345020802
|
140
|
131
|
5
|
0.0381679389312977
|
0.0357142857142857
|
GO:BP
|
GO:0051049
|
regulation of transport
|
0.0208415354136835
|
1809
|
142
|
25
|
0.176056338028169
|
0.0138197899391929
|
GO:BP
|
GO:1903900
|
regulation of viral life cycle
|
0.0209299911325264
|
153
|
74
|
4
|
0.0540540540540541
|
0.0261437908496732
|
GO:BP
|
GO:1903508
|
positive regulation of nucleic acid-templated transcription
|
0.0212541031140697
|
1617
|
142
|
23
|
0.161971830985915
|
0.0142238713667285
|
GO:BP
|
GO:0045893
|
positive regulation of transcription, DNA-templated
|
0.0212541031140697
|
1617
|
142
|
23
|
0.161971830985915
|
0.0142238713667285
|
GO:BP
|
GO:1902680
|
positive regulation of RNA biosynthetic process
|
0.0213779486484998
|
1618
|
142
|
23
|
0.161971830985915
|
0.0142150803461063
|
GO:BP
|
GO:1901983
|
regulation of protein acetylation
|
0.0214378701920005
|
78
|
72
|
3
|
0.0416666666666667
|
0.0384615384615385
|
GO:BP
|
GO:0000165
|
MAPK cascade
|
0.0221215104996503
|
935
|
96
|
12
|
0.125
|
0.0128342245989305
|
GO:BP
|
GO:0031324
|
negative regulation of cellular metabolic process
|
0.0225066198448504
|
2719
|
97
|
25
|
0.257731958762887
|
0.00919455682236116
|
GO:BP
|
GO:0097193
|
intrinsic apoptotic signaling pathway
|
0.0225066198448504
|
294
|
40
|
4
|
0.1
|
0.0136054421768707
|
GO:BP
|
GO:0050729
|
positive regulation of inflammatory response
|
0.0225681554936665
|
142
|
82
|
4
|
0.0487804878048781
|
0.028169014084507
|
GO:BP
|
GO:0060759
|
regulation of response to cytokine stimulus
|
0.0226199951213174
|
197
|
96
|
5
|
0.0520833333333333
|
0.0253807106598985
|
GO:BP
|
GO:0051336
|
regulation of hydrolase activity
|
0.0226564723325347
|
1321
|
87
|
14
|
0.160919540229885
|
0.0105980317940954
|
GO:BP
|
GO:0043408
|
regulation of MAPK cascade
|
0.0229274203290336
|
730
|
123
|
12
|
0.0975609756097561
|
0.0164383561643836
|
GO:BP
|
GO:0019538
|
protein metabolic process
|
0.0229653590425418
|
5808
|
134
|
58
|
0.432835820895522
|
0.0099862258953168
|
GO:BP
|
GO:0032880
|
regulation of protein localization
|
0.0235448577844288
|
922
|
137
|
15
|
0.109489051094891
|
0.0162689804772234
|
GO:BP
|
GO:0019725
|
cellular homeostasis
|
0.0241621568541642
|
981
|
142
|
16
|
0.112676056338028
|
0.0163098878695209
|
GO:BP
|
GO:0070266
|
necroptotic process
|
0.024435850218422
|
46
|
131
|
3
|
0.0229007633587786
|
0.0652173913043478
|
GO:BP
|
GO:0045055
|
regulated exocytosis
|
0.024435850218422
|
785
|
146
|
14
|
0.0958904109589041
|
0.0178343949044586
|
GO:BP
|
GO:0002275
|
myeloid cell activation involved in immune response
|
0.0258664904741196
|
547
|
146
|
11
|
0.0753424657534247
|
0.020109689213894
|
GO:BP
|
GO:0080090
|
regulation of primary metabolic process
|
0.0258664904741196
|
6053
|
135
|
60
|
0.444444444444444
|
0.00991244011234099
|
GO:BP
|
GO:0023051
|
regulation of signaling
|
0.0266783271575534
|
3578
|
137
|
40
|
0.291970802919708
|
0.0111794298490777
|
GO:BP
|
GO:0002444
|
myeloid leukocyte mediated immunity
|
0.0268387585512695
|
551
|
146
|
11
|
0.0753424657534247
|
0.0199637023593466
|
GO:BP
|
GO:0051346
|
negative regulation of hydrolase activity
|
0.0269181369777805
|
470
|
14
|
3
|
0.214285714285714
|
0.00638297872340425
|
GO:BP
|
GO:0045597
|
positive regulation of cell differentiation
|
0.0279128935765233
|
879
|
93
|
11
|
0.118279569892473
|
0.012514220705347
|
GO:BP
|
GO:0031669
|
cellular response to nutrient levels
|
0.0283516678469849
|
219
|
93
|
5
|
0.0537634408602151
|
0.0228310502283105
|
GO:BP
|
GO:0002237
|
response to molecule of bacterial origin
|
0.0283995139674279
|
361
|
134
|
8
|
0.0597014925373134
|
0.0221606648199446
|
GO:BP
|
GO:0051817
|
modulation of process of other organism involved in symbiotic interaction
|
0.0283995139674279
|
102
|
125
|
4
|
0.032
|
0.0392156862745098
|
GO:BP
|
GO:0007346
|
regulation of mitotic cell cycle
|
0.0289502657069311
|
619
|
132
|
11
|
0.0833333333333333
|
0.0177705977382876
|
GO:BP
|
GO:0043312
|
neutrophil degranulation
|
0.0294292173116426
|
482
|
146
|
10
|
0.0684931506849315
|
0.020746887966805
|
GO:BP
|
GO:0051050
|
positive regulation of transport
|
0.0301375952375355
|
923
|
142
|
15
|
0.105633802816901
|
0.0162513542795233
|
GO:BP
|
GO:0002283
|
neutrophil activation involved in immune response
|
0.030455830767177
|
485
|
146
|
10
|
0.0684931506849315
|
0.0206185567010309
|
GO:BP
|
GO:0016579
|
protein deubiquitination
|
0.0306928468493289
|
292
|
134
|
7
|
0.0522388059701493
|
0.023972602739726
|
GO:BP
|
GO:0065007
|
biological regulation
|
0.0311805361661862
|
12809
|
27
|
25
|
0.925925925925926
|
0.00195175267390116
|
GO:BP
|
GO:0071496
|
cellular response to external stimulus
|
0.0314646495006957
|
322
|
93
|
6
|
0.0645161290322581
|
0.0186335403726708
|
GO:BP
|
GO:0000018
|
regulation of DNA recombination
|
0.0314780507185922
|
103
|
129
|
4
|
0.0310077519379845
|
0.0388349514563107
|
GO:BP
|
GO:0070647
|
protein modification by small protein conjugation or removal
|
0.0320225137602284
|
1184
|
134
|
17
|
0.126865671641791
|
0.0143581081081081
|
GO:BP
|
GO:0002224
|
toll-like receptor signaling pathway
|
0.0337958965634165
|
161
|
134
|
5
|
0.0373134328358209
|
0.031055900621118
|
GO:BP
|
GO:0007093
|
mitotic cell cycle checkpoint
|
0.0338488766522011
|
164
|
132
|
5
|
0.0378787878787879
|
0.0304878048780488
|
GO:BP
|
GO:0051094
|
positive regulation of developmental process
|
0.0338488766522011
|
1341
|
82
|
13
|
0.158536585365854
|
0.00969425801640567
|
GO:BP
|
GO:0097300
|
programmed necrotic cell death
|
0.0338488766522011
|
54
|
131
|
3
|
0.0229007633587786
|
0.0555555555555556
|
GO:BP
|
GO:0002446
|
neutrophil mediated immunity
|
0.0338751428878796
|
497
|
146
|
10
|
0.0684931506849315
|
0.0201207243460765
|
GO:BP
|
GO:0042119
|
neutrophil activation
|
0.0342220922236748
|
498
|
146
|
10
|
0.0684931506849315
|
0.0200803212851406
|
GO:BP
|
GO:0010646
|
regulation of cell communication
|
0.0342220922236748
|
3543
|
79
|
25
|
0.316455696202532
|
0.00705616709003669
|
GO:BP
|
GO:0046718
|
viral entry into host cell
|
0.0347848869107033
|
141
|
51
|
3
|
0.0588235294117647
|
0.0212765957446809
|
GO:BP
|
GO:0043410
|
positive regulation of MAPK cascade
|
0.0349895504882367
|
539
|
58
|
6
|
0.103448275862069
|
0.0111317254174397
|
GO:BP
|
GO:0044773
|
mitotic DNA damage checkpoint
|
0.0355617590163104
|
106
|
132
|
4
|
0.0303030303030303
|
0.0377358490566038
|
GO:BP
|
GO:0031331
|
positive regulation of cellular catabolic process
|
0.0356748553180241
|
393
|
19
|
3
|
0.157894736842105
|
0.00763358778625954
|
GO:BP
|
GO:0070498
|
interleukin-1-mediated signaling pathway
|
0.0360377658376525
|
105
|
134
|
4
|
0.0298507462686567
|
0.0380952380952381
|
GO:BP
|
GO:0036230
|
granulocyte activation
|
0.0361954954305151
|
504
|
146
|
10
|
0.0684931506849315
|
0.0198412698412698
|
GO:BP
|
GO:0072331
|
signal transduction by p53 class mediator
|
0.0361954954305151
|
268
|
83
|
5
|
0.0602409638554217
|
0.0186567164179104
|
GO:BP
|
GO:1902041
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
0.0365892507816546
|
59
|
125
|
3
|
0.024
|
0.0508474576271186
|
GO:BP
|
GO:0045087
|
innate immune response
|
0.0365892507816546
|
998
|
75
|
10
|
0.133333333333333
|
0.0100200400801603
|
GO:BP
|
GO:0050792
|
regulation of viral process
|
0.0366246725146545
|
192
|
74
|
4
|
0.0540540540540541
|
0.0208333333333333
|
GO:BP
|
GO:0045088
|
regulation of innate immune response
|
0.037497475918518
|
309
|
73
|
5
|
0.0684931506849315
|
0.0161812297734628
|
GO:BP
|
GO:0006801
|
superoxide metabolic process
|
0.0375717437456315
|
67
|
112
|
3
|
0.0267857142857143
|
0.0447761194029851
|
GO:BP
|
GO:0010605
|
negative regulation of macromolecule metabolic process
|
0.0375717437456315
|
3241
|
100
|
28
|
0.28
|
0.00863930885529158
|
GO:BP
|
GO:0070646
|
protein modification by small protein removal
|
0.0376568876196744
|
310
|
134
|
7
|
0.0522388059701493
|
0.0225806451612903
|
GO:BP
|
GO:0048869
|
cellular developmental process
|
0.0376568876196744
|
4428
|
22
|
11
|
0.5
|
0.00248419150858175
|
GO:BP
|
GO:0050731
|
positive regulation of peptidyl-tyrosine phosphorylation
|
0.0378435699818956
|
198
|
73
|
4
|
0.0547945205479452
|
0.0202020202020202
|
GO:BP
|
GO:0050900
|
leukocyte migration
|
0.0380266796647135
|
511
|
146
|
10
|
0.0684931506849315
|
0.0195694716242661
|
GO:BP
|
GO:1903320
|
regulation of protein modification by small protein conjugation or removal
|
0.0380266796647135
|
243
|
131
|
6
|
0.0458015267175573
|
0.0246913580246914
|
GO:BP
|
GO:0006977
|
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
|
0.0385920853926432
|
58
|
132
|
3
|
0.0227272727272727
|
0.0517241379310345
|
GO:BP
|
GO:0070534
|
protein K63-linked ubiquitination
|
0.0393964310486377
|
59
|
131
|
3
|
0.0229007633587786
|
0.0508474576271186
|
GO:BP
|
GO:0031668
|
cellular response to extracellular stimulus
|
0.0396543839221126
|
248
|
93
|
5
|
0.0537634408602151
|
0.0201612903225806
|
GO:BP
|
GO:1902400
|
intracellular signal transduction involved in G1 DNA damage checkpoint
|
0.0398351224693564
|
59
|
132
|
3
|
0.0227272727272727
|
0.0508474576271186
|
GO:BP
|
GO:0072431
|
signal transduction involved in mitotic G1 DNA damage checkpoint
|
0.0398351224693564
|
59
|
132
|
3
|
0.0227272727272727
|
0.0508474576271186
|
GO:BP
|
GO:0044774
|
mitotic DNA integrity checkpoint
|
0.0398351224693564
|
112
|
132
|
4
|
0.0303030303030303
|
0.0357142857142857
|
GO:BP
|
GO:0010557
|
positive regulation of macromolecule biosynthetic process
|
0.0403841712605061
|
1851
|
142
|
24
|
0.169014084507042
|
0.0129659643435981
|
GO:BP
|
GO:0046916
|
cellular transition metal ion homeostasis
|
0.0410561897587574
|
116
|
129
|
4
|
0.0310077519379845
|
0.0344827586206897
|
GO:BP
|
GO:0043903
|
regulation of biological process involved in symbiotic interaction
|
0.041211347301402
|
203
|
74
|
4
|
0.0540540540540541
|
0.0197044334975369
|
GO:BP
|
GO:1902402
|
signal transduction involved in mitotic DNA damage checkpoint
|
0.0421346232757715
|
61
|
132
|
3
|
0.0227272727272727
|
0.0491803278688525
|
GO:BP
|
GO:1902403
|
signal transduction involved in mitotic DNA integrity checkpoint
|
0.0421346232757715
|
61
|
132
|
3
|
0.0227272727272727
|
0.0491803278688525
|
GO:BP
|
GO:0031328
|
positive regulation of cellular biosynthetic process
|
0.0423655830101233
|
1967
|
142
|
25
|
0.176056338028169
|
0.012709710218607
|
GO:BP
|
GO:0010467
|
gene expression
|
0.0423655830101233
|
6179
|
83
|
39
|
0.469879518072289
|
0.00631170092247937
|
GO:BP
|
GO:0031399
|
regulation of protein modification process
|
0.0427268495091062
|
1671
|
133
|
21
|
0.157894736842105
|
0.0125673249551167
|
GO:BP
|
GO:0007254
|
JNK cascade
|
0.0430259579788099
|
195
|
122
|
5
|
0.040983606557377
|
0.0256410256410256
|
GO:BP
|
GO:2000045
|
regulation of G1/S transition of mitotic cell cycle
|
0.0442809100379171
|
182
|
132
|
5
|
0.0378787878787879
|
0.0274725274725275
|
GO:BP
|
GO:0050830
|
defense response to Gram-positive bacterium
|
0.0445713120528332
|
101
|
82
|
3
|
0.0365853658536585
|
0.0297029702970297
|
GO:BP
|
GO:0072413
|
signal transduction involved in mitotic cell cycle checkpoint
|
0.0448743147688558
|
63
|
132
|
3
|
0.0227272727272727
|
0.0476190476190476
|
GO:BP
|
GO:0051051
|
negative regulation of transport
|
0.0449251459735459
|
474
|
139
|
9
|
0.0647482014388489
|
0.0189873417721519
|
GO:BP
|
GO:0019882
|
antigen processing and presentation
|
0.0453381622960536
|
234
|
144
|
6
|
0.0416666666666667
|
0.0256410256410256
|
GO:BP
|
GO:0045930
|
negative regulation of mitotic cell cycle
|
0.0453608271822983
|
333
|
132
|
7
|
0.053030303030303
|
0.021021021021021
|
GO:BP
|
GO:0031398
|
positive regulation of protein ubiquitination
|
0.0457534002412095
|
120
|
131
|
4
|
0.0305343511450382
|
0.0333333333333333
|
GO:BP
|
GO:0043299
|
leukocyte degranulation
|
0.0464733500358967
|
535
|
146
|
10
|
0.0684931506849315
|
0.0186915887850467
|
GO:BP
|
GO:0009892
|
negative regulation of metabolic process
|
0.046708426735791
|
3479
|
100
|
29
|
0.29
|
0.00833572865766025
|
GO:BP
|
GO:0009896
|
positive regulation of catabolic process
|
0.0479197332670325
|
464
|
19
|
3
|
0.157894736842105
|
0.00646551724137931
|
GO:BP
|
GO:0070997
|
neuron death
|
0.0479521995968864
|
365
|
68
|
5
|
0.0735294117647059
|
0.0136986301369863
|
GO:BP
|
GO:0031667
|
response to nutrient levels
|
0.0481536648008772
|
482
|
93
|
7
|
0.0752688172043011
|
0.0145228215767635
|
GO:BP
|
GO:0031640
|
killing of cells of other organism
|
0.0482216464528828
|
69
|
125
|
3
|
0.024
|
0.0434782608695652
|
GO:BP
|
GO:0071347
|
cellular response to interleukin-1
|
0.0485741926274287
|
185
|
134
|
5
|
0.0373134328358209
|
0.027027027027027
|
GO:BP
|
GO:0009891
|
positive regulation of biosynthetic process
|
0.0499555412010212
|
2004
|
142
|
25
|
0.176056338028169
|
0.0124750499001996
|
GO:CC
|
GO:0098552
|
side of membrane
|
9.34214281801423e-08
|
619
|
144
|
23
|
0.159722222222222
|
0.037156704361874
|
GO:CC
|
GO:0009986
|
cell surface
|
2.16211889938405e-07
|
899
|
75
|
19
|
0.253333333333333
|
0.0211345939933259
|
GO:CC
|
GO:0009897
|
external side of plasma membrane
|
7.16156473150135e-07
|
408
|
75
|
13
|
0.173333333333333
|
0.0318627450980392
|
GO:CC
|
GO:0042612
|
MHC class I protein complex
|
1.76718451921254e-05
|
8
|
144
|
4
|
0.0277777777777778
|
0.5
|
GO:CC
|
GO:0031982
|
vesicle
|
0.000318412123276433
|
4055
|
146
|
55
|
0.376712328767123
|
0.0135635018495684
|
GO:CC
|
GO:0005768
|
endosome
|
0.0009737717501105
|
987
|
144
|
21
|
0.145833333333333
|
0.0212765957446809
|
GO:CC
|
GO:0030670
|
phagocytic vesicle membrane
|
0.00112997251133468
|
76
|
144
|
6
|
0.0416666666666667
|
0.0789473684210526
|
GO:CC
|
GO:0042611
|
MHC protein complex
|
0.00122023605452442
|
24
|
144
|
4
|
0.0277777777777778
|
0.166666666666667
|
GO:CC
|
GO:0031410
|
cytoplasmic vesicle
|
0.00198855429810982
|
2424
|
146
|
36
|
0.246575342465753
|
0.0148514851485149
|
GO:CC
|
GO:0030134
|
COPII-coated ER to Golgi transport vesicle
|
0.00198855429810982
|
90
|
88
|
5
|
0.0568181818181818
|
0.0555555555555556
|
GO:CC
|
GO:0097708
|
intracellular vesicle
|
0.00198855429810982
|
2428
|
146
|
36
|
0.246575342465753
|
0.014827018121911
|
GO:CC
|
GO:0045335
|
phagocytic vesicle
|
0.00229792431990947
|
137
|
144
|
7
|
0.0486111111111111
|
0.0510948905109489
|
GO:CC
|
GO:0030659
|
cytoplasmic vesicle membrane
|
0.00255612485709312
|
779
|
146
|
17
|
0.116438356164384
|
0.0218228498074454
|
GO:CC
|
GO:0045121
|
membrane raft
|
0.00255612485709312
|
335
|
107
|
9
|
0.0841121495327103
|
0.026865671641791
|
GO:CC
|
GO:0098857
|
membrane microdomain
|
0.00255612485709312
|
335
|
107
|
9
|
0.0841121495327103
|
0.026865671641791
|
GO:CC
|
GO:0010008
|
endosome membrane
|
0.00259262659177124
|
505
|
144
|
13
|
0.0902777777777778
|
0.0257425742574257
|
GO:CC
|
GO:0012506
|
vesicle membrane
|
0.0027814672748516
|
800
|
146
|
17
|
0.116438356164384
|
0.02125
|
GO:CC
|
GO:0030658
|
transport vesicle membrane
|
0.00339674084740162
|
209
|
144
|
8
|
0.0555555555555556
|
0.0382775119617225
|
GO:CC
|
GO:0098588
|
bounding membrane of organelle
|
0.00339674084740162
|
2158
|
146
|
32
|
0.219178082191781
|
0.0148285449490269
|
GO:CC
|
GO:0031226
|
intrinsic component of plasma membrane
|
0.00448150346319654
|
1726
|
146
|
27
|
0.184931506849315
|
0.0156431054461182
|
GO:CC
|
GO:0030135
|
coated vesicle
|
0.00448150346319654
|
295
|
38
|
5
|
0.131578947368421
|
0.0169491525423729
|
GO:CC
|
GO:0005887
|
integral component of plasma membrane
|
0.00476252800566854
|
1645
|
146
|
26
|
0.178082191780822
|
0.0158054711246201
|
GO:CC
|
GO:1903561
|
extracellular vesicle
|
0.00582591226898411
|
2261
|
146
|
32
|
0.219178082191781
|
0.0141530296329058
|
GO:CC
|
GO:0043230
|
extracellular organelle
|
0.00582591226898411
|
2263
|
146
|
32
|
0.219178082191781
|
0.0141405214317278
|
GO:CC
|
GO:0055038
|
recycling endosome membrane
|
0.00582591226898411
|
84
|
144
|
5
|
0.0347222222222222
|
0.0595238095238095
|
GO:CC
|
GO:0070062
|
extracellular exosome
|
0.00615255863448198
|
2176
|
146
|
31
|
0.212328767123288
|
0.0142463235294118
|
GO:CC
|
GO:0055037
|
recycling endosome
|
0.00660142781192892
|
188
|
144
|
7
|
0.0486111111111111
|
0.0372340425531915
|
GO:CC
|
GO:0030667
|
secretory granule membrane
|
0.00660142781192892
|
303
|
146
|
9
|
0.0616438356164384
|
0.0297029702970297
|
GO:CC
|
GO:0000139
|
Golgi membrane
|
0.0080813911818955
|
771
|
144
|
15
|
0.104166666666667
|
0.0194552529182879
|
GO:CC
|
GO:0071556
|
integral component of lumenal side of endoplasmic reticulum membrane
|
0.0080813911818955
|
25
|
144
|
3
|
0.0208333333333333
|
0.12
|
GO:CC
|
GO:0098553
|
lumenal side of endoplasmic reticulum membrane
|
0.0080813911818955
|
25
|
144
|
3
|
0.0208333333333333
|
0.12
|
GO:CC
|
GO:0098797
|
plasma membrane protein complex
|
0.0080813911818955
|
694
|
144
|
14
|
0.0972222222222222
|
0.0201729106628242
|
GO:CC
|
GO:0012507
|
ER to Golgi transport vesicle membrane
|
0.0083020785454289
|
57
|
144
|
4
|
0.0277777777777778
|
0.0701754385964912
|
GO:CC
|
GO:0030666
|
endocytic vesicle membrane
|
0.0113535864134154
|
159
|
144
|
6
|
0.0416666666666667
|
0.0377358490566038
|
GO:CC
|
GO:0030176
|
integral component of endoplasmic reticulum membrane
|
0.0113535864134154
|
158
|
145
|
6
|
0.0413793103448276
|
0.0379746835443038
|
GO:CC
|
GO:0031227
|
intrinsic component of endoplasmic reticulum membrane
|
0.0138863797375333
|
166
|
145
|
6
|
0.0413793103448276
|
0.036144578313253
|
GO:CC
|
GO:0005769
|
early endosome
|
0.0149604414899496
|
378
|
89
|
7
|
0.0786516853932584
|
0.0185185185185185
|
GO:CC
|
GO:0098576
|
lumenal side of membrane
|
0.0149604414899496
|
33
|
144
|
3
|
0.0208333333333333
|
0.0909090909090909
|
GO:CC
|
GO:0005576
|
extracellular region
|
0.0149604414899496
|
4567
|
22
|
12
|
0.545454545454545
|
0.00262754543463981
|
GO:CC
|
GO:0030139
|
endocytic vesicle
|
0.0167515101937432
|
306
|
144
|
8
|
0.0555555555555556
|
0.0261437908496732
|
GO:CC
|
GO:0030662
|
coated vesicle membrane
|
0.0167515101937432
|
177
|
144
|
6
|
0.0416666666666667
|
0.0338983050847458
|
GO:CC
|
GO:0098791
|
Golgi apparatus subcompartment
|
0.0208467143398281
|
885
|
144
|
15
|
0.104166666666667
|
0.0169491525423729
|
GO:CC
|
GO:0005829
|
cytosol
|
0.0268638799950585
|
5303
|
140
|
54
|
0.385714285714286
|
0.0101829153309447
|
GO:CC
|
GO:0030133
|
transport vesicle
|
0.0275316133071845
|
414
|
144
|
9
|
0.0625
|
0.0217391304347826
|
GO:CC
|
GO:0071944
|
cell periphery
|
0.0295823636861489
|
6169
|
112
|
50
|
0.446428571428571
|
0.00810504133571081
|
GO:CC
|
GO:0016021
|
integral component of membrane
|
0.0302619448694774
|
5711
|
146
|
59
|
0.404109589041096
|
0.0103309402906671
|
GO:CC
|
GO:0099503
|
secretory vesicle
|
0.0315683841731373
|
1020
|
146
|
16
|
0.10958904109589
|
0.0156862745098039
|
GO:CC
|
GO:0031224
|
intrinsic component of membrane
|
0.0332710805223803
|
5868
|
146
|
60
|
0.410958904109589
|
0.0102249488752556
|
GO:CC
|
GO:0030672
|
synaptic vesicle membrane
|
0.0344188144585526
|
111
|
125
|
4
|
0.032
|
0.036036036036036
|
GO:CC
|
GO:0099501
|
exocytic vesicle membrane
|
0.0344188144585526
|
111
|
125
|
4
|
0.032
|
0.036036036036036
|
GO:CC
|
GO:0031901
|
early endosome membrane
|
0.0361530383416138
|
159
|
89
|
4
|
0.0449438202247191
|
0.0251572327044025
|
GO:CC
|
GO:0016020
|
membrane
|
0.0365137086623281
|
9838
|
125
|
79
|
0.632
|
0.00803008741614149
|
GO:CC
|
GO:0005886
|
plasma membrane
|
0.0411884082863615
|
5681
|
112
|
46
|
0.410714285714286
|
0.00809716599190283
|
GO:CC
|
GO:0043235
|
receptor complex
|
0.0485151162169535
|
522
|
129
|
9
|
0.0697674418604651
|
0.0172413793103448
|
GO:MF
|
GO:0005031
|
tumor necrosis factor-activated receptor activity
|
2.55470965471676e-06
|
10
|
8
|
3
|
0.375
|
0.3
|
GO:MF
|
GO:0005035
|
death receptor activity
|
2.55470965471676e-06
|
12
|
8
|
3
|
0.375
|
0.25
|
GO:MF
|
GO:0019955
|
cytokine binding
|
6.08037477783693e-05
|
138
|
63
|
7
|
0.111111111111111
|
0.0507246376811594
|
GO:MF
|
GO:0032813
|
tumor necrosis factor receptor superfamily binding
|
6.88398279265386e-05
|
49
|
122
|
6
|
0.0491803278688525
|
0.122448979591837
|
GO:MF
|
GO:0043028
|
cysteine-type endopeptidase regulator activity involved in apoptotic process
|
6.88398279265386e-05
|
38
|
83
|
5
|
0.0602409638554217
|
0.131578947368421
|
GO:MF
|
GO:0005164
|
tumor necrosis factor receptor binding
|
0.000143976914259
|
32
|
122
|
5
|
0.040983606557377
|
0.15625
|
GO:MF
|
GO:0004896
|
cytokine receptor activity
|
0.000409566704358733
|
99
|
86
|
6
|
0.0697674418604651
|
0.0606060606060606
|
GO:MF
|
GO:0019899
|
enzyme binding
|
0.000430868346069543
|
2074
|
134
|
33
|
0.246268656716418
|
0.0159112825458052
|
GO:MF
|
GO:0061134
|
peptidase regulator activity
|
0.00101637991587673
|
224
|
15
|
4
|
0.266666666666667
|
0.0178571428571429
|
GO:MF
|
GO:0046977
|
TAP binding
|
0.00126453535200421
|
9
|
144
|
3
|
0.0208333333333333
|
0.333333333333333
|
GO:MF
|
GO:0140375
|
immune receptor activity
|
0.00126453535200421
|
133
|
86
|
6
|
0.0697674418604651
|
0.0451127819548872
|
GO:MF
|
GO:0002020
|
protease binding
|
0.00134169365975506
|
133
|
132
|
7
|
0.053030303030303
|
0.0526315789473684
|
GO:MF
|
GO:0016505
|
peptidase activator activity involved in apoptotic process
|
0.00219604390494784
|
19
|
83
|
3
|
0.036144578313253
|
0.157894736842105
|
GO:MF
|
GO:0019900
|
kinase binding
|
0.00261665302232755
|
752
|
134
|
16
|
0.119402985074627
|
0.0212765957446809
|
GO:MF
|
GO:0004888
|
transmembrane signaling receptor activity
|
0.00360042648810197
|
1269
|
9
|
5
|
0.555555555555556
|
0.00394011032308905
|
GO:MF
|
GO:0038023
|
signaling receptor activity
|
0.00425445517484463
|
1458
|
68
|
15
|
0.220588235294118
|
0.0102880658436214
|
GO:MF
|
GO:0005515
|
protein binding
|
0.00425445517484463
|
14767
|
146
|
132
|
0.904109589041096
|
0.00893885013882305
|
GO:MF
|
GO:0060089
|
molecular transducer activity
|
0.00425445517484463
|
1458
|
68
|
15
|
0.220588235294118
|
0.0102880658436214
|
GO:MF
|
GO:0042802
|
identical protein binding
|
0.00498473583771202
|
2067
|
133
|
29
|
0.218045112781955
|
0.0140299951620706
|
GO:MF
|
GO:0004866
|
endopeptidase inhibitor activity
|
0.00500514428432479
|
176
|
14
|
3
|
0.214285714285714
|
0.0170454545454545
|
GO:MF
|
GO:0030414
|
peptidase inhibitor activity
|
0.00531069842065308
|
182
|
14
|
3
|
0.214285714285714
|
0.0164835164835165
|
GO:MF
|
GO:0061135
|
endopeptidase regulator activity
|
0.00562466866687916
|
188
|
14
|
3
|
0.214285714285714
|
0.0159574468085106
|
GO:MF
|
GO:0016504
|
peptidase activator activity
|
0.0133347704036713
|
42
|
83
|
3
|
0.036144578313253
|
0.0714285714285714
|
GO:MF
|
GO:0019838
|
growth factor binding
|
0.0156840256253837
|
138
|
63
|
4
|
0.0634920634920635
|
0.0289855072463768
|
GO:MF
|
GO:0140272
|
exogenous protein binding
|
0.0156840256253837
|
77
|
51
|
3
|
0.0588235294117647
|
0.038961038961039
|
GO:MF
|
GO:0001618
|
virus receptor activity
|
0.0156840256253837
|
76
|
51
|
3
|
0.0588235294117647
|
0.0394736842105263
|
GO:MF
|
GO:0042605
|
peptide antigen binding
|
0.0185705496631942
|
30
|
144
|
3
|
0.0208333333333333
|
0.1
|
GO:MF
|
GO:0005126
|
cytokine receptor binding
|
0.0210534113389553
|
275
|
122
|
7
|
0.0573770491803279
|
0.0254545454545455
|
GO:MF
|
GO:0098772
|
molecular function regulator
|
0.0210534113389553
|
2363
|
16
|
7
|
0.4375
|
0.00296233601354211
|
GO:MF
|
GO:0004857
|
enzyme inhibitor activity
|
0.0227363421522579
|
385
|
14
|
3
|
0.214285714285714
|
0.00779220779220779
|
GO:MF
|
GO:0005507
|
copper ion binding
|
0.0244927514140549
|
61
|
88
|
3
|
0.0340909090909091
|
0.0491803278688525
|
GO:MF
|
GO:0019901
|
protein kinase binding
|
0.0269113752724692
|
673
|
134
|
12
|
0.0895522388059701
|
0.0178306092124814
|
GO:MF
|
GO:0044389
|
ubiquitin-like protein ligase binding
|
0.0334965005976278
|
314
|
122
|
7
|
0.0573770491803279
|
0.0222929936305732
|
GO:MF
|
GO:0005102
|
signaling receptor binding
|
0.0378999488351065
|
1672
|
98
|
17
|
0.173469387755102
|
0.0101674641148325
|
HP
|
HP:0012192
|
Cutaneous T-cell lymphoma
|
0.00229351249688238
|
3
|
50
|
3
|
0.06
|
1
|
HP
|
HP:0002733
|
Abnormality of the lymph nodes
|
0.00337594181951003
|
196
|
18
|
7
|
0.388888888888889
|
0.0357142857142857
|
HP
|
HP:0002716
|
Lymphadenopathy
|
0.00337594181951003
|
187
|
18
|
7
|
0.388888888888889
|
0.0374331550802139
|
HP
|
HP:0003765
|
Psoriasiform dermatitis
|
0.00394286902256355
|
25
|
144
|
7
|
0.0486111111111111
|
0.28
|
HP
|
HP:0012190
|
T-cell lymphoma
|
0.00431285853544782
|
11
|
68
|
4
|
0.0588235294117647
|
0.363636363636364
|
HP
|
HP:0001019
|
Erythroderma
|
0.00431285853544782
|
49
|
50
|
6
|
0.12
|
0.122448979591837
|
HP
|
HP:0002665
|
Lymphoma
|
0.00771135890295667
|
98
|
18
|
5
|
0.277777777777778
|
0.0510204081632653
|
HP
|
HP:0011895
|
Anemia due to reduced life span of red cells
|
0.0141234701077047
|
122
|
18
|
5
|
0.277777777777778
|
0.040983606557377
|
HP
|
HP:0000554
|
Uveitis
|
0.0141234701077047
|
45
|
9
|
3
|
0.333333333333333
|
0.0666666666666667
|
HP
|
HP:0100533
|
Inflammatory abnormality of the eye
|
0.0141234701077047
|
193
|
18
|
6
|
0.333333333333333
|
0.0310880829015544
|
HP
|
HP:0001878
|
Hemolytic anemia
|
0.0141234701077047
|
122
|
18
|
5
|
0.277777777777778
|
0.040983606557377
|
HP
|
HP:0032169
|
Severe infection
|
0.0156387178962472
|
28
|
16
|
3
|
0.1875
|
0.107142857142857
|
HP
|
HP:0004844
|
Coombs-positive hemolytic anemia
|
0.0156387178962472
|
7
|
68
|
3
|
0.0441176470588235
|
0.428571428571429
|
HP
|
HP:0010701
|
Abnormal immunoglobulin level
|
0.0161136030357518
|
219
|
18
|
6
|
0.333333333333333
|
0.0273972602739726
|
HP
|
HP:0005372
|
Abnormality of B cell physiology
|
0.0161136030357518
|
220
|
18
|
6
|
0.333333333333333
|
0.0272727272727273
|
HP
|
HP:0012539
|
Non-Hodgkin lymphoma
|
0.0162758382310792
|
35
|
68
|
5
|
0.0735294117647059
|
0.142857142857143
|
HP
|
HP:0031409
|
Abnormal lymphocyte physiology
|
0.0231819285283843
|
246
|
18
|
6
|
0.333333333333333
|
0.024390243902439
|
HP
|
HP:0011450
|
Unusual CNS infection
|
0.0231819285283843
|
87
|
48
|
6
|
0.125
|
0.0689655172413793
|
HP
|
HP:0005368
|
Abnormality of humoral immunity
|
0.0231819285283843
|
249
|
18
|
6
|
0.333333333333333
|
0.0240963855421687
|
HP
|
HP:0004332
|
Abnormal lymphocyte morphology
|
0.0231819285283843
|
156
|
50
|
8
|
0.16
|
0.0512820512820513
|
HP
|
HP:0100725
|
Lichenification
|
0.0246642412516739
|
13
|
50
|
3
|
0.06
|
0.230769230769231
|
HP
|
HP:0100806
|
Sepsis
|
0.0246642412516739
|
91
|
48
|
6
|
0.125
|
0.0659340659340659
|
HP
|
HP:0032158
|
Unusual infection by anatomical site
|
0.0246642412516739
|
91
|
48
|
6
|
0.125
|
0.0659340659340659
|
HP
|
HP:0100646
|
Thyroiditis
|
0.0246642412516739
|
41
|
68
|
5
|
0.0735294117647059
|
0.121951219512195
|
HP
|
HP:0001973
|
Autoimmune thrombocytopenia
|
0.0284716218047221
|
39
|
18
|
3
|
0.166666666666667
|
0.0769230769230769
|
HP
|
HP:0002720
|
Decreased circulating IgA level
|
0.0284716218047221
|
39
|
18
|
3
|
0.166666666666667
|
0.0769230769230769
|
HP
|
HP:0001287
|
Meningitis
|
0.0404596410144052
|
72
|
68
|
6
|
0.0882352941176471
|
0.0833333333333333
|
HP
|
HP:0002721
|
Immunodeficiency
|
0.04984946468527
|
204
|
18
|
5
|
0.277777777777778
|
0.0245098039215686
|
HP
|
HP:0008404
|
Nail dystrophy
|
0.04984946468527
|
114
|
18
|
4
|
0.222222222222222
|
0.0350877192982456
|
HP
|
HP:0045073
|
Serositis
|
0.04984946468527
|
40
|
88
|
5
|
0.0568181818181818
|
0.125
|
HP
|
HP:0002113
|
Pulmonary infiltrates
|
0.04984946468527
|
53
|
38
|
4
|
0.105263157894737
|
0.0754716981132075
|
KEGG
|
KEGG:04060
|
Cytokine-cytokine receptor interaction
|
4.78690639641314e-07
|
293
|
9
|
7
|
0.777777777777778
|
0.0238907849829352
|
KEGG
|
KEGG:04940
|
Type I diabetes mellitus
|
0.000240725423822697
|
40
|
82
|
6
|
0.0731707317073171
|
0.15
|
KEGG
|
KEGG:04064
|
NF-kappa B signaling pathway
|
0.00129933434977986
|
102
|
125
|
9
|
0.072
|
0.0882352941176471
|
KEGG
|
KEGG:04514
|
Cell adhesion molecules
|
0.00129933434977986
|
146
|
50
|
7
|
0.14
|
0.0479452054794521
|
KEGG
|
KEGG:05320
|
Autoimmune thyroid disease
|
0.00187620878558315
|
49
|
68
|
5
|
0.0735294117647059
|
0.102040816326531
|
KEGG
|
KEGG:04659
|
Th17 cell differentiation
|
0.00339762940670321
|
104
|
86
|
7
|
0.0813953488372093
|
0.0673076923076923
|
KEGG
|
KEGG:05330
|
Allograft rejection
|
0.00448781724111349
|
34
|
68
|
4
|
0.0588235294117647
|
0.117647058823529
|
KEGG
|
KEGG:05332
|
Graft-versus-host disease
|
0.005486131538323
|
37
|
68
|
4
|
0.0588235294117647
|
0.108108108108108
|
KEGG
|
KEGG:05166
|
Human T-cell leukemia virus 1 infection
|
0.00587812069718143
|
216
|
82
|
9
|
0.109756097560976
|
0.0416666666666667
|
KEGG
|
KEGG:04668
|
TNF signaling pathway
|
0.00587812069718143
|
112
|
123
|
8
|
0.0650406504065041
|
0.0714285714285714
|
KEGG
|
KEGG:05321
|
Inflammatory bowel disease
|
0.00794336484178949
|
62
|
86
|
5
|
0.0581395348837209
|
0.0806451612903226
|
KEGG
|
KEGG:04658
|
Th1 and Th2 cell differentiation
|
0.00794336484178949
|
89
|
61
|
5
|
0.0819672131147541
|
0.0561797752808989
|
KEGG
|
KEGG:05340
|
Primary immunodeficiency
|
0.0180544547708229
|
37
|
48
|
3
|
0.0625
|
0.0810810810810811
|
KEGG
|
KEGG:04660
|
T cell receptor signaling pathway
|
0.0375040839285354
|
103
|
50
|
4
|
0.08
|
0.0388349514563107
|
KEGG
|
KEGG:05169
|
Epstein-Barr virus infection
|
0.0375040839285354
|
198
|
146
|
10
|
0.0684931506849315
|
0.0505050505050505
|
KEGG
|
KEGG:04210
|
Apoptosis
|
0.0375040839285354
|
136
|
39
|
4
|
0.102564102564103
|
0.0294117647058824
|
KEGG
|
KEGG:04612
|
Antigen processing and presentation
|
0.0375040839285354
|
69
|
75
|
4
|
0.0533333333333333
|
0.0579710144927536
|
KEGG
|
KEGG:05416
|
Viral myocarditis
|
0.0433804752651784
|
56
|
50
|
3
|
0.06
|
0.0535714285714286
|
KEGG
|
KEGG:05162
|
Measles
|
0.0489085893187738
|
139
|
125
|
7
|
0.056
|
0.0503597122302158
|
REAC
|
REAC:R-HSA-1280215
|
Cytokine Signaling in Immune system
|
4.13934852315735e-09
|
842
|
10
|
10
|
1
|
0.0118764845605701
|
REAC
|
REAC:R-HSA-5668541
|
TNFR2 non-canonical NF-kB pathway
|
1.05829580109336e-08
|
100
|
9
|
6
|
0.666666666666667
|
0.06
|
REAC
|
REAC:R-HSA-8877330
|
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
|
1.70430520170471e-07
|
10
|
18
|
4
|
0.222222222222222
|
0.4
|
REAC
|
REAC:R-HSA-5669034
|
TNFs bind their physiological receptors
|
2.39887111965685e-07
|
29
|
85
|
7
|
0.0823529411764706
|
0.241379310344828
|
REAC
|
REAC:R-HSA-168256
|
Immune System
|
9.57407959578588e-06
|
2139
|
10
|
10
|
1
|
0.00467508181393174
|
REAC
|
REAC:R-HSA-1236977
|
Endosomal/Vacuolar pathway
|
0.000702121619686333
|
11
|
144
|
4
|
0.0277777777777778
|
0.363636363636364
|
REAC
|
REAC:R-HSA-449147
|
Signaling by Interleukins
|
0.00247472405026354
|
446
|
134
|
17
|
0.126865671641791
|
0.0381165919282511
|
REAC
|
REAC:R-HSA-983170
|
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
|
0.0128269169188094
|
25
|
144
|
4
|
0.0277777777777778
|
0.16
|
REAC
|
REAC:R-HSA-8878171
|
Transcriptional regulation by RUNX1
|
0.0128269169188094
|
200
|
18
|
4
|
0.222222222222222
|
0.02
|
REAC
|
REAC:R-HSA-164938
|
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
|
0.0128269169188094
|
20
|
75
|
3
|
0.04
|
0.15
|
REAC
|
REAC:R-HSA-877300
|
Interferon gamma signaling
|
0.0128269169188094
|
87
|
75
|
5
|
0.0666666666666667
|
0.0574712643678161
|
REAC
|
REAC:R-HSA-164952
|
The role of Nef in HIV-1 replication and disease pathogenesis
|
0.025329114552821
|
26
|
75
|
3
|
0.04
|
0.115384615384615
|
REAC
|
REAC:R-HSA-6785807
|
Interleukin-4 and Interleukin-13 signaling
|
0.0283881070542887
|
110
|
73
|
5
|
0.0684931506849315
|
0.0454545454545455
|
REAC
|
REAC:R-HSA-909733
|
Interferon alpha/beta signaling
|
0.0302836525667268
|
66
|
73
|
4
|
0.0547945205479452
|
0.0606060606060606
|
REAC
|
REAC:R-HSA-5689896
|
Ovarian tumor domain proteases
|
0.0319295430098471
|
38
|
134
|
4
|
0.0298507462686567
|
0.105263157894737
|
TF
|
TF:M10004
|
Factor: NF-kappaB2; motif: GGGRAANYCCC
|
0.0144774557461634
|
1073
|
102
|
19
|
0.186274509803922
|
0.0177073625349487
|
WP
|
WP:WP254
|
Apoptosis
|
0.00191464709454546
|
86
|
132
|
9
|
0.0681818181818182
|
0.104651162790698
|
WP
|
WP:WP2328
|
Allograft Rejection
|
0.00191464709454546
|
88
|
68
|
7
|
0.102941176470588
|
0.0795454545454545
|
WP
|
WP:WP1772
|
Apoptosis Modulation and Signaling
|
0.00240920489911031
|
93
|
132
|
9
|
0.0681818181818182
|
0.0967741935483871
|
WP
|
WP:WP453
|
Inflammatory Response Pathway
|
0.00343712376458123
|
33
|
50
|
4
|
0.08
|
0.121212121212121
|
WP
|
WP:WP69
|
T-Cell antigen Receptor (TCR) Signaling Pathway
|
0.00704827346046841
|
91
|
68
|
6
|
0.0882352941176471
|
0.0659340659340659
|
WP
|
WP:WP4484
|
Control of immune tolerance by vasoactive intestinal peptide
|
0.0071278661861044
|
13
|
68
|
3
|
0.0441176470588235
|
0.230769230769231
|
WP
|
WP:WP3863
|
T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection
|
0.0203558745243
|
62
|
50
|
4
|
0.08
|
0.0645161290322581
|
WP
|
WP:WP4754
|
IL-18 signaling pathway
|
0.0396803838925085
|
279
|
7
|
3
|
0.428571428571429
|
0.010752688172043
|
WP
|
WP:WP4559
|
Interactions between immune cells and microRNAs in tumor microenvironment
|
0.0461305555872009
|
40
|
48
|
3
|
0.0625
|
0.075
|