pM12 program activity among Myeloid cells

Activation of pM12
pM12 gene program activation in Myeloid cells.
Gene program activation of pM12 by different cell subtypes
pM12 gene program activation among cells of different subtypes (Myeloid cells).

pM12 top program genes

Top genes of pM12 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pM12 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pM12
pM12 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:725 P2X7 receptor signalling complex 0.00067117809053293 12 13 3 0.230769230769231 0.25
GO:BP GO:0009408 response to heat 6.31726804399408e-24 159 26 16 0.615384615384615 0.10062893081761
GO:BP GO:0006457 protein folding 6.84947845875018e-24 225 26 17 0.653846153846154 0.0755555555555556
GO:BP GO:0009266 response to temperature stimulus 8.26643396471586e-22 228 26 16 0.615384615384615 0.0701754385964912
GO:BP GO:0006986 response to unfolded protein 1.18536230207844e-21 184 25 15 0.6 0.0815217391304348
GO:BP GO:0035966 response to topologically incorrect protein 5.04595060513312e-21 205 25 15 0.6 0.0731707317073171
GO:BP GO:0034605 cellular response to heat 6.96102363051332e-20 118 26 13 0.5 0.110169491525424
GO:BP GO:1900034 regulation of cellular response to heat 7.3076675539888e-18 79 50 13 0.26 0.164556962025316
GO:BP GO:0006458 'de novo' protein folding 1.01478232641145e-17 40 73 12 0.164383561643836 0.3
GO:BP GO:0061077 chaperone-mediated protein folding 3.3611574629251e-17 61 73 13 0.178082191780822 0.213114754098361
GO:BP GO:0051085 chaperone cofactor-dependent protein refolding 3.6816959571285e-17 31 73 11 0.150684931506849 0.354838709677419
GO:BP GO:0051084 'de novo' posttranslational protein folding 2.33784875297378e-16 36 73 11 0.150684931506849 0.305555555555556
GO:BP GO:0042026 protein refolding 6.42948211744327e-15 23 17 7 0.411764705882353 0.304347826086957
GO:BP GO:0009628 response to abiotic stimulus 6.42948211744327e-15 1261 26 19 0.730769230769231 0.0150674068199841
GO:BP GO:0070841 inclusion body assembly 5.8247313826587e-11 24 24 6 0.25 0.25
GO:BP GO:0033554 cellular response to stress 1.12568142331315e-10 2111 19 16 0.842105263157895 0.00757934628138323
GO:BP GO:0090084 negative regulation of inclusion body assembly 1.55876004064832e-10 11 69 6 0.0869565217391304 0.545454545454545
GO:BP GO:0080135 regulation of cellular response to stress 1.87814803987257e-10 725 16 11 0.6875 0.0151724137931034
GO:BP GO:0031647 regulation of protein stability 3.06806790275959e-10 300 65 14 0.215384615384615 0.0466666666666667
GO:BP GO:0090083 regulation of inclusion body assembly 1.89010929439234e-09 17 24 5 0.208333333333333 0.294117647058824
GO:BP GO:0006950 response to stress 5.33014283642016e-09 4170 19 18 0.947368421052632 0.00431654676258993
GO:BP GO:0080134 regulation of response to stress 8.56616081295482e-09 1443 16 12 0.75 0.00831600831600832
GO:BP GO:0050821 protein stabilization 8.56616081295482e-09 193 65 11 0.169230769230769 0.0569948186528497
GO:BP GO:0050790 regulation of catalytic activity 2.11331100076433e-08 2545 26 18 0.692307692307692 0.00707269155206287
GO:BP GO:0010033 response to organic substance 2.71187658719176e-08 3412 20 17 0.85 0.00498241500586166
GO:BP GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 3.01353807306194e-08 12 18 4 0.222222222222222 0.333333333333333
GO:BP GO:0051131 chaperone-mediated protein complex assembly 5.66142054824424e-08 21 12 4 0.333333333333333 0.19047619047619
GO:BP GO:0065009 regulation of molecular function 8.09434794086008e-08 3221 26 19 0.730769230769231 0.00589878919590189
GO:BP GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 9.40013203920868e-08 111 19 6 0.315789473684211 0.0540540540540541
GO:BP GO:0043620 regulation of DNA-templated transcription in response to stress 1.24902639527013e-07 117 19 6 0.315789473684211 0.0512820512820513
GO:BP GO:0034620 cellular response to unfolded protein 1.56474352736604e-07 149 16 6 0.375 0.0402684563758389
GO:BP GO:0035967 cellular response to topologically incorrect protein 3.02616435959976e-07 168 16 6 0.375 0.0357142857142857
GO:BP GO:0043085 positive regulation of catalytic activity 3.02616435959976e-07 1418 24 13 0.541666666666667 0.00916784203102962
GO:BP GO:0044093 positive regulation of molecular function 3.58857591693697e-07 1771 24 14 0.583333333333333 0.00790513833992095
GO:BP GO:0009893 positive regulation of metabolic process 4.3669288449896e-07 3783 21 17 0.80952380952381 0.00449378799894264
GO:BP GO:0016032 viral process 5.31135813184313e-07 942 19 10 0.526315789473684 0.0106157112526539
GO:BP GO:0044403 biological process involved in symbiotic interaction 9.24506686702826e-07 1001 19 10 0.526315789473684 0.00999000999000999
GO:BP GO:0060548 negative regulation of cell death 1.57226447315954e-06 1038 24 11 0.458333333333333 0.010597302504817
GO:BP GO:0019222 regulation of metabolic process 1.71317036229177e-06 7148 40 33 0.825 0.00461667599328484
GO:BP GO:0010941 regulation of cell death 1.81254416856927e-06 1720 20 12 0.6 0.00697674418604651
GO:BP GO:0071310 cellular response to organic substance 3.05924870947741e-06 2776 20 14 0.7 0.00504322766570605
GO:BP GO:0031396 regulation of protein ubiquitination 3.05924870947741e-06 211 19 6 0.315789473684211 0.028436018957346
GO:BP GO:0072594 establishment of protein localization to organelle 3.05924870947741e-06 584 19 8 0.421052631578947 0.0136986301369863
GO:BP GO:0042981 regulation of apoptotic process 3.30331259020059e-06 1549 19 11 0.578947368421053 0.00710135571336346
GO:BP GO:0042221 response to chemical 3.30331259020059e-06 4781 20 17 0.85 0.00355574147667852
GO:BP GO:0031329 regulation of cellular catabolic process 3.50029756769441e-06 866 19 9 0.473684210526316 0.0103926096997691
GO:BP GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 3.52826167206136e-06 40 19 4 0.210526315789474 0.1
GO:BP GO:0043067 regulation of programmed cell death 3.75388371613603e-06 1582 19 11 0.578947368421053 0.00695322376738306
GO:BP GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 3.75388371613603e-06 41 19 4 0.210526315789474 0.0975609756097561
GO:BP GO:0001775 cell activation 3.79671652155274e-06 1495 13 9 0.692307692307692 0.00602006688963211
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 4.16121845358419e-06 3483 20 15 0.75 0.00430663221360896
GO:BP GO:0043066 negative regulation of apoptotic process 4.49492874385432e-06 921 24 10 0.416666666666667 0.01085776330076
GO:BP GO:0002274 myeloid leukocyte activation 4.94525750314179e-06 667 13 7 0.538461538461538 0.0104947526236882
GO:BP GO:1903320 regulation of protein modification by small protein conjugation or removal 4.96293192241071e-06 243 19 6 0.315789473684211 0.0246913580246914
GO:BP GO:0060255 regulation of macromolecule metabolic process 5.21346515970002e-06 6603 40 31 0.775 0.00469483568075117
GO:BP GO:0043069 negative regulation of programmed cell death 5.23329208690993e-06 943 24 10 0.416666666666667 0.0106044538706257
GO:BP GO:0034097 response to cytokine 6.82789495855772e-06 1226 20 10 0.5 0.00815660685154975
GO:BP GO:1905323 telomerase holoenzyme complex assembly 6.95669832170675e-06 6 40 3 0.075 0.5
GO:BP GO:0002366 leukocyte activation involved in immune response 7.10183252651844e-06 717 13 7 0.538461538461538 0.0097629009762901
GO:BP GO:0002263 cell activation involved in immune response 7.26446352307246e-06 721 13 7 0.538461538461538 0.00970873786407767
GO:BP GO:0061684 chaperone-mediated autophagy 1.05209501246851e-05 16 16 3 0.1875 0.1875
GO:BP GO:0009894 regulation of catabolic process 1.09909065091735e-05 1033 19 9 0.473684210526316 0.00871248789932236
GO:BP GO:0051345 positive regulation of hydrolase activity 1.17271030369409e-05 783 24 9 0.375 0.0114942528735632
GO:BP GO:0043312 neutrophil degranulation 1.56817217019784e-05 482 13 6 0.461538461538462 0.012448132780083
GO:BP GO:0002283 neutrophil activation involved in immune response 1.60404099408494e-05 485 13 6 0.461538461538462 0.0123711340206186
GO:BP GO:0048583 regulation of response to stimulus 1.68493610799559e-05 4278 19 15 0.789473684210526 0.00350631136044881
GO:BP GO:0006915 apoptotic process 1.72125591842635e-05 1990 50 19 0.38 0.00954773869346734
GO:BP GO:0002446 neutrophil mediated immunity 1.77589644223396e-05 497 13 6 0.461538461538462 0.0120724346076459
GO:BP GO:0042119 neutrophil activation 1.77589644223396e-05 498 13 6 0.461538461538462 0.0120481927710843
GO:BP GO:0031324 negative regulation of cellular metabolic process 1.81524899150225e-05 2719 26 15 0.576923076923077 0.0055167340934167
GO:BP GO:0036230 granulocyte activation 1.85679497182907e-05 504 13 6 0.461538461538462 0.0119047619047619
GO:BP GO:0009889 regulation of biosynthetic process 1.95423794427288e-05 4361 21 16 0.761904761904762 0.00366888328365054
GO:BP GO:0017038 protein import 1.95423794427288e-05 205 16 5 0.3125 0.024390243902439
GO:BP GO:0008219 cell death 2.0574552465598e-05 2292 20 12 0.6 0.00523560209424084
GO:BP GO:0045321 leukocyte activation 2.0574552465598e-05 1332 13 8 0.615384615384615 0.00600600600600601
GO:BP GO:0070887 cellular response to chemical stimulus 2.07854384831453e-05 3393 20 14 0.7 0.00412614205717654
GO:BP GO:0002443 leukocyte mediated immunity 2.10671254903181e-05 877 13 7 0.538461538461538 0.00798175598631699
GO:BP GO:0031323 regulation of cellular metabolic process 2.2328236506463e-05 6269 36 27 0.75 0.00430690700271176
GO:BP GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 2.24420395818638e-05 73 19 4 0.210526315789474 0.0547945205479452
GO:BP GO:0051973 positive regulation of telomerase activity 2.24420395818638e-05 34 40 4 0.1 0.117647058823529
GO:BP GO:0032781 positive regulation of ATPase activity 2.24420395818638e-05 57 24 4 0.166666666666667 0.0701754385964912
GO:BP GO:0043299 leukocyte degranulation 2.28605247231155e-05 535 13 6 0.461538461538462 0.011214953271028
GO:BP GO:0010556 regulation of macromolecule biosynthetic process 2.38379807263398e-05 4102 20 15 0.75 0.00365675280351048
GO:BP GO:0002275 myeloid cell activation involved in immune response 2.51944150974613e-05 547 13 6 0.461538461538462 0.0109689213893967
GO:BP GO:0002444 myeloid leukocyte mediated immunity 2.60131202509402e-05 551 13 6 0.461538461538462 0.0108892921960073
GO:BP GO:0019058 viral life cycle 2.68325692924307e-05 353 19 6 0.315789473684211 0.0169971671388102
GO:BP GO:0031325 positive regulation of cellular metabolic process 2.88249383246988e-05 3274 21 14 0.666666666666667 0.00427611484422724
GO:BP GO:0071345 cellular response to cytokine stimulus 2.88463290808624e-05 1132 20 9 0.45 0.00795053003533569
GO:BP GO:0043488 regulation of mRNA stability 2.88780286140051e-05 191 19 5 0.263157894736842 0.0261780104712042
GO:BP GO:0097190 apoptotic signaling pathway 3.37071991581893e-05 600 19 7 0.368421052631579 0.0116666666666667
GO:BP GO:0043487 regulation of RNA stability 3.63940197418195e-05 201 19 5 0.263157894736842 0.0248756218905473
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 3.91993857972155e-05 2518 26 14 0.538461538461538 0.00555996822875298
GO:BP GO:0012501 programmed cell death 3.91993857972155e-05 2143 50 19 0.38 0.00886607559496034
GO:BP GO:0007179 transforming growth factor beta receptor signaling pathway 3.95041831233118e-05 206 19 5 0.263157894736842 0.0242718446601942
GO:BP GO:0032273 positive regulation of protein polymerization 3.95041831233118e-05 141 4 3 0.75 0.0212765957446809
GO:BP GO:0006402 mRNA catabolic process 3.96350486259415e-05 384 19 6 0.315789473684211 0.015625
GO:BP GO:0061013 regulation of mRNA catabolic process 4.48435950013508e-05 213 19 5 0.263157894736842 0.0234741784037559
GO:BP GO:0002221 pattern recognition receptor signaling pathway 4.48435950013508e-05 213 19 5 0.263157894736842 0.0234741784037559
GO:BP GO:0032268 regulation of cellular protein metabolic process 4.68812727895883e-05 2541 33 16 0.484848484848485 0.00629673356946084
GO:BP GO:0080090 regulation of primary metabolic process 4.68812727895883e-05 6053 38 27 0.710526315789474 0.00446059805055344
GO:BP GO:1903364 positive regulation of cellular protein catabolic process 4.7953055394282e-05 154 4 3 0.75 0.0194805194805195
GO:BP GO:0051338 regulation of transferase activity 4.86626757892262e-05 1035 49 13 0.26530612244898 0.01256038647343
GO:BP GO:0048518 positive regulation of biological process 5.08536896169632e-05 6363 21 18 0.857142857142857 0.00282885431400283
GO:BP GO:1903362 regulation of cellular protein catabolic process 5.41574092652413e-05 257 29 6 0.206896551724138 0.0233463035019455
GO:BP GO:0030163 protein catabolic process 5.69698909318032e-05 974 19 8 0.421052631578947 0.0082135523613963
GO:BP GO:0006401 RNA catabolic process 6.21133428023591e-05 424 19 6 0.315789473684211 0.0141509433962264
GO:BP GO:0043462 regulation of ATPase activity 6.49136830982129e-05 80 24 4 0.166666666666667 0.05
GO:BP GO:0030522 intracellular receptor signaling pathway 6.53881449224488e-05 284 42 7 0.166666666666667 0.0246478873239437
GO:BP GO:0001819 positive regulation of cytokine production 6.81480738087828e-05 452 11 5 0.454545454545455 0.0110619469026549
GO:BP GO:0071897 DNA biosynthetic process 7.14057265563368e-05 195 40 6 0.15 0.0307692307692308
GO:BP GO:0033365 protein localization to organelle 7.1919072677713e-05 1017 19 8 0.421052631578947 0.00786627335299902
GO:BP GO:0006605 protein targeting 7.1919072677713e-05 441 19 6 0.315789473684211 0.0136054421768707
GO:BP GO:0048522 positive regulation of cellular process 8.07530928156453e-05 5757 21 17 0.80952380952381 0.00295292687163453
GO:BP GO:0051336 regulation of hydrolase activity 8.07530928156453e-05 1321 25 10 0.4 0.00757002271006813
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 8.07530928156453e-05 5848 44 29 0.659090909090909 0.00495896032831737
GO:BP GO:0030162 regulation of proteolysis 8.07530928156453e-05 752 25 8 0.32 0.0106382978723404
GO:BP GO:0051972 regulation of telomerase activity 8.07530928156453e-05 51 40 4 0.1 0.0784313725490196
GO:BP GO:0071560 cellular response to transforming growth factor beta stimulus 8.70777900454083e-05 256 19 5 0.263157894736842 0.01953125
GO:BP GO:0051246 regulation of protein metabolic process 8.70777900454083e-05 2704 33 16 0.484848484848485 0.00591715976331361
GO:BP GO:0001817 regulation of cytokine production 8.94848129763246e-05 806 12 6 0.5 0.00744416873449132
GO:BP GO:0071559 response to transforming growth factor beta 9.47341672978518e-05 262 19 5 0.263157894736842 0.0190839694656489
GO:BP GO:0072655 establishment of protein localization to mitochondrion 9.86913458624758e-05 143 16 4 0.25 0.027972027972028
GO:BP GO:0009057 macromolecule catabolic process 0.000100051587777306 1468 19 9 0.473684210526316 0.0061307901907357
GO:BP GO:0070585 protein localization to mitochondrion 0.000107836897807818 147 16 4 0.25 0.0272108843537415
GO:BP GO:0001816 cytokine production 0.000111202805049622 844 12 6 0.5 0.00710900473933649
GO:BP GO:0002755 MyD88-dependent toll-like receptor signaling pathway 0.000111623465733651 37 19 3 0.157894736842105 0.0810810810810811
GO:BP GO:1903426 regulation of reactive oxygen species biosynthetic process 0.000111623465733651 111 21 4 0.19047619047619 0.036036036036036
GO:BP GO:0044265 cellular macromolecule catabolic process 0.000115700560449502 1231 13 7 0.538461538461538 0.00568643379366369
GO:BP GO:2000112 regulation of cellular macromolecule biosynthetic process 0.000115700560449502 4071 20 14 0.7 0.00343895848685827
GO:BP GO:0042769 DNA damage response, detection of DNA damage 0.000124321206459815 39 19 3 0.157894736842105 0.0769230769230769
GO:BP GO:0045055 regulated exocytosis 0.000124321206459815 785 13 6 0.461538461538462 0.00764331210191083
GO:BP GO:0045732 positive regulation of protein catabolic process 0.000124321206459815 237 4 3 0.75 0.0126582278481013
GO:BP GO:0032271 regulation of protein polymerization 0.000124321206459815 236 4 3 0.75 0.0127118644067797
GO:BP GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 0.000124321206459815 129 19 4 0.210526315789474 0.0310077519379845
GO:BP GO:0044087 regulation of cellular component biogenesis 0.000125065186363449 990 4 4 1 0.00404040404040404
GO:BP GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 0.000134396156719102 132 19 4 0.210526315789474 0.0303030303030303
GO:BP GO:0019221 cytokine-mediated signaling pathway 0.000141318186315219 810 13 6 0.461538461538462 0.00740740740740741
GO:BP GO:0002252 immune effector process 0.000160143101477838 1309 13 7 0.538461538461538 0.0053475935828877
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.000160761782251892 263 4 3 0.75 0.0114068441064639
GO:BP GO:0006886 intracellular protein transport 0.000172301905463621 1186 19 8 0.421052631578947 0.00674536256323777
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.000172301905463621 1477 12 7 0.583333333333333 0.004739336492891
GO:BP GO:2000573 positive regulation of DNA biosynthetic process 0.000185239099187958 67 40 4 0.1 0.0597014925373134
GO:BP GO:0043170 macromolecule metabolic process 0.000185244598081232 9796 42 36 0.857142857142857 0.00367496937525521
GO:BP GO:0031326 regulation of cellular biosynthetic process 0.000185244598081232 4273 20 14 0.7 0.00327638661362041
GO:BP GO:0038034 signal transduction in absence of ligand 0.000185244598081232 71 38 4 0.105263157894737 0.0563380281690141
GO:BP GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 0.000185244598081232 71 38 4 0.105263157894737 0.0563380281690141
GO:BP GO:0009892 negative regulation of metabolic process 0.000196412469213542 3479 26 15 0.576923076923077 0.00431158378844496
GO:BP GO:0007004 telomere maintenance via telomerase 0.000201205518888777 69 40 4 0.1 0.0579710144927536
GO:BP GO:1903409 reactive oxygen species biosynthetic process 0.000201540830516108 135 21 4 0.19047619047619 0.0296296296296296
GO:BP GO:0034655 nucleobase-containing compound catabolic process 0.000219703376338828 567 19 6 0.315789473684211 0.0105820105820106
GO:BP GO:0006278 RNA-dependent DNA biosynthetic process 0.000221665484632181 71 40 4 0.1 0.0563380281690141
GO:BP GO:0009059 macromolecule biosynthetic process 0.000229466513681507 5114 61 33 0.540983606557377 0.00645287446226046
GO:BP GO:0007017 microtubule-based process 0.000229466513681507 881 19 7 0.368421052631579 0.00794551645856981
GO:BP GO:0051247 positive regulation of protein metabolic process 0.000229466513681507 1564 12 7 0.583333333333333 0.00447570332480818
GO:BP GO:0051258 protein polymerization 0.000229466513681507 305 4 3 0.75 0.00983606557377049
GO:BP GO:0006887 exocytosis 0.000232165369640488 904 13 6 0.461538461538462 0.00663716814159292
GO:BP GO:0016567 protein ubiquitination 0.000243232083750819 892 19 7 0.368421052631579 0.007847533632287
GO:BP GO:0051649 establishment of localization in cell 0.000243232083750819 2813 13 9 0.692307692307692 0.00319943121222894
GO:BP GO:0051092 positive regulation of NF-kappaB transcription factor activity 0.000252520438246811 162 19 4 0.210526315789474 0.0246913580246914
GO:BP GO:0062197 cellular response to chemical stress 0.000259077241086808 365 18 5 0.277777777777778 0.0136986301369863
GO:BP GO:0010970 transport along microtubule 0.000260894694329853 164 19 4 0.210526315789474 0.024390243902439
GO:BP GO:0048584 positive regulation of response to stimulus 0.000272156524892044 2344 12 8 0.666666666666667 0.00341296928327645
GO:BP GO:1904589 regulation of protein import 0.000273216817367879 65 16 3 0.1875 0.0461538461538462
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 0.000275876569477583 167 19 4 0.210526315789474 0.0239520958083832
GO:BP GO:0046700 heterocycle catabolic process 0.000277359464087496 602 19 6 0.315789473684211 0.00996677740863787
GO:BP GO:0051641 cellular localization 0.000277766867395259 3541 21 13 0.619047619047619 0.00367127929963287
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.000282986303280776 236 14 4 0.285714285714286 0.0169491525423729
GO:BP GO:0044270 cellular nitrogen compound catabolic process 0.000288349840783219 608 19 6 0.315789473684211 0.00986842105263158
GO:BP GO:0019219 regulation of nucleobase-containing compound metabolic process 0.000288349840783219 4091 19 13 0.684210526315789 0.00317770716206307
GO:BP GO:1903311 regulation of mRNA metabolic process 0.000290266438437923 356 19 5 0.263157894736842 0.0140449438202247
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 0.000301644019687238 2255 19 10 0.526315789473684 0.00443458980044346
GO:BP GO:0071900 regulation of protein serine/threonine kinase activity 0.000301644019687238 503 33 7 0.212121212121212 0.0139165009940358
GO:BP GO:2001233 regulation of apoptotic signaling pathway 0.000312539873622187 363 19 5 0.263157894736842 0.0137741046831956
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 0.000313655865235051 223 49 6 0.122448979591837 0.0269058295964126
GO:BP GO:0019439 aromatic compound catabolic process 0.000317392354562084 623 19 6 0.315789473684211 0.00963081861958266
GO:BP GO:0010833 telomere maintenance via telomere lengthening 0.000328279346227271 82 40 4 0.1 0.0487804878048781
GO:BP GO:0034613 cellular protein localization 0.000328279346227271 2014 21 10 0.476190476190476 0.00496524329692155
GO:BP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 0.000328279346227271 369 19 5 0.263157894736842 0.013550135501355
GO:BP GO:0016192 vesicle-mediated transport 0.000330870722561196 2180 13 8 0.615384615384615 0.0036697247706422
GO:BP GO:0070727 cellular macromolecule localization 0.000334277485305805 2024 21 10 0.476190476190476 0.00494071146245059
GO:BP GO:0034622 cellular protein-containing complex assembly 0.000350734143970191 1107 12 6 0.5 0.00542005420054201
GO:BP GO:1901565 organonitrogen compound catabolic process 0.000350998848984507 1358 19 8 0.421052631578947 0.00589101620029455
GO:BP GO:0042176 regulation of protein catabolic process 0.000350998848984507 401 29 6 0.206896551724138 0.0149625935162095
GO:BP GO:0032446 protein modification by small protein conjugation 0.000356696659560844 973 19 7 0.368421052631579 0.00719424460431655
GO:BP GO:0045926 negative regulation of growth 0.000360370960937224 255 89 8 0.0898876404494382 0.0313725490196078
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 0.000362232402297498 3241 26 14 0.538461538461538 0.00431965442764579
GO:BP GO:0061136 regulation of proteasomal protein catabolic process 0.000362232402297498 186 19 4 0.210526315789474 0.021505376344086
GO:BP GO:0007018 microtubule-based movement 0.000365322381861465 383 19 5 0.263157894736842 0.0130548302872063
GO:BP GO:1901361 organic cyclic compound catabolic process 0.000369615243990205 651 19 6 0.315789473684211 0.00921658986175115
GO:BP GO:0050896 response to stimulus 0.000378285920809301 9407 20 19 0.95 0.0020197725098331
GO:BP GO:0031331 positive regulation of cellular catabolic process 0.000382096070891607 393 4 3 0.75 0.00763358778625954
GO:BP GO:0034645 cellular macromolecule biosynthetic process 0.000402530440880385 5051 61 32 0.524590163934426 0.00633537913284498
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.000408810621218756 3083 13 9 0.692307692307692 0.00291923451183912
GO:BP GO:0099111 microtubule-based transport 0.000435405410507695 198 19 4 0.210526315789474 0.0202020202020202
GO:BP GO:0010628 positive regulation of gene expression 0.000438186129159986 1160 17 7 0.411764705882353 0.00603448275862069
GO:BP GO:1903428 positive regulation of reactive oxygen species biosynthetic process 0.000444733874575472 62 21 3 0.142857142857143 0.0483870967741935
GO:BP GO:0042592 homeostatic process 0.000448260986281857 1981 40 14 0.35 0.00706713780918728
GO:BP GO:0030705 cytoskeleton-dependent intracellular transport 0.000463080257721888 202 19 4 0.210526315789474 0.0198019801980198
GO:BP GO:0022607 cellular component assembly 0.00048117293774723 3010 19 11 0.578947368421053 0.00365448504983389
GO:BP GO:0045862 positive regulation of proteolysis 0.000489761468480637 378 11 4 0.363636363636364 0.0105820105820106
GO:BP GO:0006839 mitochondrial transport 0.000492901021889861 284 27 5 0.185185185185185 0.0176056338028169
GO:BP GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 0.000501843010753042 100 14 3 0.214285714285714 0.03
GO:BP GO:0030308 negative regulation of cell growth 0.00051652364502635 192 64 6 0.09375 0.03125
GO:BP GO:0015031 protein transport 0.00051652364502635 1929 19 9 0.473684210526316 0.0046656298600311
GO:BP GO:0065003 protein-containing complex assembly 0.000525426338201777 1680 13 7 0.538461538461538 0.00416666666666667
GO:BP GO:0010468 regulation of gene expression 0.000534618841853092 5196 19 14 0.736842105263158 0.00269438029253272
GO:BP GO:0033120 positive regulation of RNA splicing 0.000534618841853092 40 35 3 0.0857142857142857 0.075
GO:BP GO:0044260 cellular macromolecule metabolic process 0.000534618841853092 8390 45 34 0.755555555555556 0.00405244338498212
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.000544359980634982 460 4 3 0.75 0.00652173913043478
GO:BP GO:0009896 positive regulation of catabolic process 0.000556505733612534 464 4 3 0.75 0.00646551724137931
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 0.000572644019056756 434 19 5 0.263157894736842 0.0115207373271889
GO:BP GO:0048523 negative regulation of cellular process 0.000583001080920213 5139 30 19 0.633333333333333 0.00369721735746254
GO:BP GO:0015833 peptide transport 0.000583001080920213 1971 19 9 0.473684210526316 0.0045662100456621
GO:BP GO:0006979 response to oxidative stress 0.000594187536625411 466 18 5 0.277777777777778 0.0107296137339056
GO:BP GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 0.000596459207563639 221 19 4 0.210526315789474 0.0180995475113122
GO:BP GO:0071363 cellular response to growth factor stimulus 0.000599651103304749 731 19 6 0.315789473684211 0.00820793433652531
GO:BP GO:0051129 negative regulation of cellular component organization 0.000599651103304749 759 3 3 1 0.00395256916996047
GO:BP GO:0045859 regulation of protein kinase activity 0.000636852615184222 809 33 8 0.242424242424242 0.00988875154511743
GO:BP GO:2000377 regulation of reactive oxygen species metabolic process 0.000638674045265489 203 21 4 0.19047619047619 0.0197044334975369
GO:BP GO:0016049 cell growth 0.000641059354192114 495 4 3 0.75 0.00606060606060606
GO:BP GO:0007167 enzyme linked receptor protein signaling pathway 0.000644226943398169 1103 19 7 0.368421052631579 0.00634632819582956
GO:BP GO:0042886 amide transport 0.000646596283100676 2007 19 9 0.473684210526316 0.00448430493273543
GO:BP GO:0051090 regulation of DNA-binding transcription factor activity 0.000682567834381323 456 19 5 0.263157894736842 0.0109649122807018
GO:BP GO:0021954 central nervous system neuron development 0.000699905194112156 84 19 3 0.157894736842105 0.0357142857142857
GO:BP GO:0006626 protein targeting to mitochondrion 0.000703936677875238 101 16 3 0.1875 0.0297029702970297
GO:BP GO:0070848 response to growth factor 0.000703936677875238 759 19 6 0.315789473684211 0.00790513833992095
GO:BP GO:0045184 establishment of protein localization 0.000703936677875238 2035 19 9 0.473684210526316 0.00442260442260442
GO:BP GO:0009409 response to cold 0.000703936677875238 48 89 4 0.0449438202247191 0.0833333333333333
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.000729248631995572 1082 26 8 0.307692307692308 0.00739371534195933
GO:BP GO:0034599 cellular response to oxidative stress 0.00077914948069262 316 6 3 0.5 0.00949367088607595
GO:BP GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 0.00077914948069262 88 19 3 0.157894736842105 0.0340909090909091
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.000785877129845018 540 4 3 0.75 0.00555555555555556
GO:BP GO:2000278 regulation of DNA biosynthetic process 0.000807317033559449 112 40 4 0.1 0.0357142857142857
GO:BP GO:0031399 regulation of protein modification process 0.000811308763982874 1671 14 7 0.5 0.00418910831837223
GO:BP GO:0043065 positive regulation of apoptotic process 0.000816912001118725 604 34 7 0.205882352941176 0.0115894039735099
GO:BP GO:0044257 cellular protein catabolic process 0.000820347139641663 813 12 5 0.416666666666667 0.00615006150061501
GO:BP GO:0051702 biological process involved in interaction with symbiont 0.000830307337064189 96 18 3 0.166666666666667 0.03125
GO:BP GO:0044085 cellular component biogenesis 0.000841103506839036 3257 19 11 0.578947368421053 0.00337734111145226
GO:BP GO:0010498 proteasomal protein catabolic process 0.000897147531791942 491 19 5 0.263157894736842 0.010183299389002
GO:BP GO:0070647 protein modification by small protein conjugation or removal 0.000922573635377844 1184 19 7 0.368421052631579 0.00591216216216216
GO:BP GO:0043068 positive regulation of programmed cell death 0.000945533430168253 621 34 7 0.205882352941176 0.0112721417069243
GO:BP GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.000947192721437126 257 19 4 0.210526315789474 0.0155642023346304
GO:BP GO:0051716 cellular response to stimulus 0.00100031006179588 7781 20 17 0.85 0.00218480915049479
GO:BP GO:0009058 biosynthetic process 0.00100735427326246 6340 21 16 0.761904761904762 0.00252365930599369
GO:BP GO:0032880 regulation of protein localization 0.00100735427326246 922 24 7 0.291666666666667 0.00759219088937093
GO:BP GO:0051248 negative regulation of protein metabolic process 0.00103741514169315 1151 26 8 0.307692307692308 0.00695047784535187
GO:BP GO:0043549 regulation of kinase activity 0.00105813139734462 921 49 10 0.204081632653061 0.01085776330076
GO:BP GO:0051091 positive regulation of DNA-binding transcription factor activity 0.00111261802947761 270 19 4 0.210526315789474 0.0148148148148148
GO:BP GO:0043933 protein-containing complex subunit organization 0.00116156666135835 1963 13 7 0.538461538461538 0.00356597045338767
GO:BP GO:0006810 transport 0.00116386956942994 5224 14 11 0.785714285714286 0.00210566615620214
GO:BP GO:0007005 mitochondrion organization 0.00120157033601023 561 18 5 0.277777777777778 0.0089126559714795
GO:BP GO:0019538 protein metabolic process 0.00132179659508696 5808 33 21 0.636363636363636 0.00361570247933884
GO:BP GO:0032940 secretion by cell 0.00135216017914574 1364 13 6 0.461538461538462 0.00439882697947214
GO:BP GO:0016071 mRNA metabolic process 0.00135407540092016 874 19 6 0.315789473684211 0.0068649885583524
GO:BP GO:1902531 regulation of intracellular signal transduction 0.0013790905540928 1842 14 7 0.5 0.00380021715526602
GO:BP GO:0009890 negative regulation of biosynthetic process 0.00140456185401477 1740 19 8 0.421052631578947 0.00459770114942529
GO:BP GO:0009891 positive regulation of biosynthetic process 0.00141390649291044 2004 21 9 0.428571428571429 0.00449101796407186
GO:BP GO:1901575 organic substance catabolic process 0.00142699935618607 2267 19 9 0.473684210526316 0.00397000441111601
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 0.00146785306003807 294 19 4 0.210526315789474 0.0136054421768707
GO:BP GO:0051234 establishment of localization 0.00147096234326542 5372 14 11 0.785714285714286 0.00204765450483991
GO:BP GO:0071704 organic substance metabolic process 0.00148479993778837 11326 42 37 0.880952380952381 0.00326681970686915
GO:BP GO:0034654 nucleobase-containing compound biosynthetic process 0.00150098273221952 4199 19 12 0.631578947368421 0.00285782329125982
GO:BP GO:0046907 intracellular transport 0.00151322126899545 1767 19 8 0.421052631578947 0.00452744765138653
GO:BP GO:0000122 negative regulation of transcription by RNA polymerase II 0.00153226625633253 901 19 6 0.315789473684211 0.00665926748057714
GO:BP GO:0010942 positive regulation of cell death 0.00154877658706218 684 34 7 0.205882352941176 0.010233918128655
GO:BP GO:0140352 export from cell 0.00157781092595313 1418 13 6 0.461538461538462 0.00423131170662906
GO:BP GO:0043484 regulation of RNA splicing 0.0016051442058628 160 35 4 0.114285714285714 0.025
GO:BP GO:0008637 apoptotic mitochondrial changes 0.0016051442058628 126 18 3 0.166666666666667 0.0238095238095238
GO:BP GO:0009719 response to endogenous stimulus 0.0016051442058628 1683 20 8 0.4 0.0047534165181224
GO:BP GO:2000379 positive regulation of reactive oxygen species metabolic process 0.0016051442058628 107 21 3 0.142857142857143 0.0280373831775701
GO:BP GO:0071705 nitrogen compound transport 0.00162903963408702 2322 19 9 0.473684210526316 0.00387596899224806
GO:BP GO:1901576 organic substance biosynthetic process 0.00164436639084153 6248 20 15 0.75 0.00240076824583867
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 0.00164896630106864 5017 19 13 0.684210526315789 0.00259118995415587
GO:BP GO:0018130 heterocycle biosynthetic process 0.00168878476726855 4269 19 12 0.631578947368421 0.0028109627547435
GO:BP GO:0045892 negative regulation of transcription, DNA-templated 0.00169878611716917 1337 19 7 0.368421052631579 0.00523560209424084
GO:BP GO:1903507 negative regulation of nucleic acid-templated transcription 0.00170976718922971 1339 19 7 0.368421052631579 0.00522778192681105
GO:BP GO:0019438 aromatic compound biosynthetic process 0.00171052972616018 4278 19 12 0.631578947368421 0.00280504908835905
GO:BP GO:1902679 negative regulation of RNA biosynthetic process 0.00171598555407667 1341 19 7 0.368421052631579 0.0052199850857569
GO:BP GO:0044248 cellular catabolic process 0.00172005779306815 2347 19 9 0.473684210526316 0.00383468257349808
GO:BP GO:0010629 negative regulation of gene expression 0.00176041879630414 1460 13 6 0.461538461538462 0.00410958904109589
GO:BP GO:0090287 regulation of cellular response to growth factor stimulus 0.00176041879630414 315 19 4 0.210526315789474 0.0126984126984127
GO:BP GO:0002682 regulation of immune system process 0.00178206849025115 1617 12 6 0.5 0.00371057513914657
GO:BP GO:1901214 regulation of neuron death 0.00190621228108427 323 19 4 0.210526315789474 0.0123839009287926
GO:BP GO:0072593 reactive oxygen species metabolic process 0.00190621228108427 290 21 4 0.19047619047619 0.0137931034482759
GO:BP GO:0051128 regulation of cellular component organization 0.00191597689530749 2412 4 4 1 0.00165837479270315
GO:BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0019610285801002 217 50 5 0.1 0.0230414746543779
GO:BP GO:0046903 secretion 0.0020049783267847 1501 13 6 0.461538461538462 0.00399733510992672
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.00206586543076548 1037 12 5 0.416666666666667 0.00482160077145612
GO:BP GO:0010564 regulation of cell cycle process 0.00206586543076548 809 4 3 0.75 0.00370828182941904
GO:BP GO:0065008 regulation of biological quality 0.00210073744869789 4131 42 20 0.476190476190476 0.00484144274993948
GO:BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process 0.0021466546582833 1887 19 8 0.421052631578947 0.00423953365129836
GO:BP GO:0006508 proteolysis 0.00218086936314225 1836 29 10 0.344827586206897 0.00544662309368192
GO:BP GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.00218436855713952 136 19 3 0.157894736842105 0.0220588235294118
GO:BP GO:0048519 negative regulation of biological process 0.00219697805690922 5757 30 19 0.633333333333333 0.0033003300330033
GO:BP GO:0008104 protein localization 0.0022259486518804 2770 24 11 0.458333333333333 0.00397111913357401
GO:BP GO:1901362 organic cyclic compound biosynthetic process 0.00231644191327988 4439 19 12 0.631578947368421 0.0027033115566569
GO:BP GO:0097435 supramolecular fiber organization 0.002326539728495 734 25 6 0.24 0.00817438692098093
GO:BP GO:0090304 nucleic acid metabolic process 0.00235194399566176 5226 19 13 0.684210526315789 0.00248756218905473
GO:BP GO:1903827 regulation of cellular protein localization 0.00238883298535917 572 21 5 0.238095238095238 0.00874125874125874
GO:BP GO:1903747 regulation of establishment of protein localization to mitochondrion 0.00239854747093399 72 88 4 0.0454545454545455 0.0555555555555556
GO:BP GO:0007254 JNK cascade 0.00239866324172256 195 33 4 0.121212121212121 0.0205128205128205
GO:BP GO:0051253 negative regulation of RNA metabolic process 0.00247620373401985 1445 19 7 0.368421052631579 0.00484429065743945
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 0.00260062136436474 655 19 5 0.263157894736842 0.00763358778625954
GO:BP GO:0006955 immune response 0.00260062136436474 2311 13 7 0.538461538461538 0.00302899177845089
GO:BP GO:0006468 protein phosphorylation 0.00260062136436474 1668 44 12 0.272727272727273 0.00719424460431655
GO:BP GO:0070925 organelle assembly 0.00260062136436474 895 4 3 0.75 0.00335195530726257
GO:BP GO:0000723 telomere maintenance 0.00262630810170387 165 40 4 0.1 0.0242424242424242
GO:BP GO:0071702 organic substance transport 0.00262737087481113 2766 21 10 0.476190476190476 0.00361532899493854
GO:BP GO:0051347 positive regulation of transferase activity 0.00264729412395951 689 49 8 0.163265306122449 0.011611030478955
GO:BP GO:0010557 positive regulation of macromolecule biosynthetic process 0.00264729412395951 1851 20 8 0.4 0.00432198811453269
GO:BP GO:1903047 mitotic cell cycle process 0.00269561407836289 911 4 3 0.75 0.00329308452250274
GO:BP GO:0019941 modification-dependent protein catabolic process 0.00269561407836289 662 19 5 0.263157894736842 0.00755287009063444
GO:BP GO:0070997 neuron death 0.0027114414287986 365 19 4 0.210526315789474 0.010958904109589
GO:BP GO:0010467 gene expression 0.0027114414287986 6179 19 14 0.736842105263158 0.0022657387926849
GO:BP GO:0001666 response to hypoxia 0.0027114414287986 367 50 6 0.12 0.0163487738419619
GO:BP GO:0051252 regulation of RNA metabolic process 0.00272846640564829 3822 19 11 0.578947368421053 0.00287807430664574
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 0.00276314616613756 240 50 5 0.1 0.0208333333333333
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 0.00283795865674132 673 19 5 0.263157894736842 0.00742942050520059
GO:BP GO:0044267 cellular protein metabolic process 0.00284328424628648 5229 33 19 0.575757575757576 0.00363358194683496
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.00292952807753356 1455 6 4 0.666666666666667 0.00274914089347079
GO:BP GO:0007166 cell surface receptor signaling pathway 0.00308747228894216 3210 19 10 0.526315789473684 0.00311526479750779
GO:BP GO:0040007 growth 0.00308747228894216 967 4 3 0.75 0.0031023784901758
GO:BP GO:0031400 negative regulation of protein modification process 0.00317297196047844 578 6 3 0.5 0.00519031141868512
GO:BP GO:0002224 toll-like receptor signaling pathway 0.00317297196047844 161 19 3 0.157894736842105 0.0186335403726708
GO:BP GO:0036293 response to decreased oxygen levels 0.00320694743815865 382 50 6 0.12 0.0157068062827225
GO:BP GO:0060249 anatomical structure homeostasis 0.00320694743815865 482 40 6 0.15 0.012448132780083
GO:BP GO:0002376 immune system process 0.0032074606328448 3278 13 8 0.615384615384615 0.0024405125076266
GO:BP GO:0032200 telomere organization 0.00324317730918445 178 40 4 0.1 0.0224719101123595
GO:BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process 0.00341042450915168 1548 19 7 0.368421052631579 0.00452196382428941
GO:BP GO:0006820 anion transport 0.0034733552406432 2889 21 10 0.476190476190476 0.00346140533056421
GO:BP GO:1900182 positive regulation of protein localization to nucleus 0.00382352327396425 90 36 3 0.0833333333333333 0.0333333333333333
GO:BP GO:0000278 mitotic cell cycle 0.00385779272664109 1059 4 3 0.75 0.0028328611898017
GO:BP GO:0008152 metabolic process 0.00391872228671768 11827 42 37 0.880952380952381 0.00312843493700854
GO:BP GO:0051603 proteolysis involved in cellular protein catabolic process 0.00430229677002397 750 19 5 0.263157894736842 0.00666666666666667
GO:BP GO:0070482 response to oxygen levels 0.00431959792079466 408 50 6 0.12 0.0147058823529412
GO:BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process 0.00442752622466608 1628 19 7 0.368421052631579 0.0042997542997543
GO:BP GO:0051403 stress-activated MAPK cascade 0.00443207098561287 272 50 5 0.1 0.0183823529411765
GO:BP GO:0009056 catabolic process 0.00443341336053829 2744 19 9 0.473684210526316 0.0032798833819242
GO:BP GO:0051726 regulation of cell cycle 0.00445586148949115 1236 18 6 0.333333333333333 0.00485436893203883
GO:BP GO:0010558 negative regulation of macromolecule biosynthetic process 0.0045599384284544 1639 19 7 0.368421052631579 0.00427089688834655
GO:BP GO:0021953 central nervous system neuron differentiation 0.00461714373619318 188 19 3 0.157894736842105 0.0159574468085106
GO:BP GO:0035556 intracellular signal transduction 0.00472995772471932 2772 19 9 0.473684210526316 0.00324675324675325
GO:BP GO:0051130 positive regulation of cellular component organization 0.00476618629933852 1153 4 3 0.75 0.002601908065915
GO:BP GO:0051054 positive regulation of DNA metabolic process 0.00495154501336499 203 40 4 0.1 0.0197044334975369
GO:BP GO:0006139 nucleobase-containing compound metabolic process 0.00512223066328675 5746 13 10 0.769230769230769 0.00174034110685694
GO:BP GO:0010608 posttranscriptional regulation of gene expression 0.00512223066328675 896 53 9 0.169811320754717 0.0100446428571429
GO:BP GO:0044249 cellular biosynthetic process 0.00520340876253658 6154 20 14 0.7 0.00227494312642184
GO:BP GO:0006914 autophagy 0.00522357503433873 543 16 4 0.25 0.00736648250460405
GO:BP GO:0061919 process utilizing autophagic mechanism 0.00522357503433873 543 16 4 0.25 0.00736648250460405
GO:BP GO:0031098 stress-activated protein kinase signaling cascade 0.00546204572240962 288 50 5 0.1 0.0173611111111111
GO:BP GO:0031327 negative regulation of cellular biosynthetic process 0.0055701603564054 1707 19 7 0.368421052631579 0.00410076157000586
GO:BP GO:0016310 phosphorylation 0.00557695747642659 2138 49 14 0.285714285714286 0.00654817586529467
GO:BP GO:0033036 macromolecule localization 0.00557695747642659 3218 27 12 0.444444444444444 0.00372902423865755
GO:BP GO:0043523 regulation of neuron apoptotic process 0.0055836205334716 216 18 3 0.166666666666667 0.0138888888888889
GO:BP GO:0052548 regulation of endopeptidase activity 0.00572124155838738 437 50 6 0.12 0.0137299771167048
GO:BP GO:0071901 negative regulation of protein serine/threonine kinase activity 0.00582875303752027 150 26 3 0.115384615384615 0.02
GO:BP GO:0042325 regulation of phosphorylation 0.0058669944789016 1431 49 11 0.224489795918367 0.0076869322152341
GO:BP GO:0001932 regulation of protein phosphorylation 0.0058669944789016 1240 19 6 0.315789473684211 0.00483870967741936
GO:BP GO:0006355 regulation of transcription, DNA-templated 0.00590792430823819 3534 19 10 0.526315789473684 0.00282965478211658
GO:BP GO:1903506 regulation of nucleic acid-templated transcription 0.00590936018969325 3535 19 10 0.526315789473684 0.00282885431400283
GO:BP GO:2001141 regulation of RNA biosynthetic process 0.00595306739595972 3540 19 10 0.526315789473684 0.00282485875706215
GO:BP GO:0046483 heterocycle metabolic process 0.00610593830747668 5904 13 10 0.769230769230769 0.00169376693766938
GO:BP GO:0051223 regulation of protein transport 0.006485766843711 586 16 4 0.25 0.0068259385665529
GO:BP GO:0006725 cellular aromatic compound metabolic process 0.00651390719766568 5956 13 10 0.769230769230769 0.00167897918065816
GO:BP GO:0051179 localization 0.00660499058058267 6901 17 13 0.764705882352941 0.00188378495870164
GO:BP GO:0007049 cell cycle 0.00660499058058267 1902 44 12 0.272727272727273 0.00630914826498423
GO:BP GO:0038093 Fc receptor signaling pathway 0.00695717420967017 238 18 3 0.166666666666667 0.0126050420168067
GO:BP GO:0051348 negative regulation of transferase activity 0.00706405320007914 310 30 4 0.133333333333333 0.0129032258064516
GO:BP GO:0070201 regulation of establishment of protein localization 0.00727530294055989 611 16 4 0.25 0.00654664484451719
GO:BP GO:0071496 cellular response to external stimulus 0.00742441808584004 322 49 5 0.102040816326531 0.015527950310559
GO:BP GO:0052547 regulation of peptidase activity 0.00742441808584004 467 50 6 0.12 0.012847965738758
GO:BP GO:0090087 regulation of peptide transport 0.00754321049297821 618 16 4 0.25 0.00647249190938511
GO:BP GO:0044092 negative regulation of molecular function 0.00775552388799698 1219 96 15 0.15625 0.0123051681706317
GO:BP GO:0051402 neuron apoptotic process 0.00775552388799698 250 18 3 0.166666666666667 0.012
GO:BP GO:0022402 cell cycle process 0.0079781439176963 1439 4 3 0.75 0.00208478109798471
GO:BP GO:0006351 transcription, DNA-templated 0.00808335461348587 3714 19 10 0.526315789473684 0.00269251480883145
GO:BP GO:0097659 nucleic acid-templated transcription 0.00808553958842332 3715 19 10 0.526315789473684 0.00269179004037685
GO:BP GO:0032774 RNA biosynthetic process 0.0082998683603133 3731 19 10 0.526315789473684 0.00268024658268561
GO:BP GO:0045860 positive regulation of protein kinase activity 0.00846170726923624 534 19 4 0.210526315789474 0.00749063670411985
GO:BP GO:1901564 organonitrogen compound metabolic process 0.00850803880055459 6792 33 21 0.636363636363636 0.00309187279151943
GO:BP GO:1901360 organic cyclic compound metabolic process 0.00856800496942903 6201 13 10 0.769230769230769 0.00161264312207708
GO:BP GO:0009968 negative regulation of signal transduction 0.00860181892407001 1364 19 6 0.315789473684211 0.00439882697947214
GO:BP GO:0002831 regulation of response to biotic stimulus 0.00917813211759026 415 12 3 0.25 0.0072289156626506
GO:BP GO:0032879 regulation of localization 0.00920742940209437 2872 24 10 0.416666666666667 0.00348189415041783
GO:BP GO:0043086 negative regulation of catalytic activity 0.00949332554079033 851 30 6 0.2 0.00705052878965922
GO:BP GO:0060341 regulation of cellular localization 0.00976713006612877 851 21 5 0.238095238095238 0.00587544065804935
GO:BP GO:0006275 regulation of DNA replication 0.009820620640569 111 44 3 0.0681818181818182 0.027027027027027
GO:BP GO:0009967 positive regulation of signal transduction 0.00983356239232779 1598 12 5 0.416666666666667 0.00312891113892365
GO:BP GO:0043405 regulation of MAP kinase activity 0.0098466500322206 316 33 4 0.121212121212121 0.0126582278481013
GO:BP GO:0071902 positive regulation of protein serine/threonine kinase activity 0.0098466500322206 316 33 4 0.121212121212121 0.0126582278481013
GO:BP GO:0071495 cellular response to endogenous stimulus 0.0100842425647421 1422 19 6 0.315789473684211 0.00421940928270042
GO:BP GO:1900180 regulation of protein localization to nucleus 0.0102281609805118 139 36 3 0.0833333333333333 0.0215827338129496
GO:BP GO:0006259 DNA metabolic process 0.0102552443332847 965 19 5 0.263157894736842 0.00518134715025907
GO:BP GO:0061024 membrane organization 0.0105257666801232 973 19 5 0.263157894736842 0.00513874614594039
GO:BP GO:0006357 regulation of transcription by RNA polymerase II 0.0105257666801232 2555 19 8 0.421052631578947 0.00313111545988258
GO:BP GO:0051239 regulation of multicellular organismal process 0.0110137738716196 2861 21 9 0.428571428571429 0.00314575323313527
GO:BP GO:1903829 positive regulation of cellular protein localization 0.0112677990462173 303 36 4 0.111111111111111 0.0132013201320132
GO:BP GO:0010648 negative regulation of cell communication 0.0113743086442992 1468 19 6 0.315789473684211 0.00408719346049046
GO:BP GO:0023057 negative regulation of signaling 0.0114363029166702 1471 19 6 0.315789473684211 0.00407885791978246
GO:BP GO:0002684 positive regulation of immune system process 0.0117030551514018 1065 18 5 0.277777777777778 0.00469483568075117
GO:BP GO:0032103 positive regulation of response to external stimulus 0.0117030896738909 513 11 3 0.272727272727273 0.00584795321637427
GO:BP GO:0016070 RNA metabolic process 0.0118273560951994 4710 19 11 0.578947368421053 0.00233545647558386
GO:BP GO:0044237 cellular metabolic process 0.0119943411011979 10871 42 34 0.80952380952381 0.00312758715849508
GO:BP GO:0033674 positive regulation of kinase activity 0.012014099107123 608 19 4 0.210526315789474 0.00657894736842105
GO:BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 0.0120966480407036 291 19 3 0.157894736842105 0.0103092783505155
GO:BP GO:0034641 cellular nitrogen compound metabolic process 0.0123856063624489 6563 13 10 0.769230769230769 0.0015236934328813
GO:BP GO:0010647 positive regulation of cell communication 0.012715063522145 1777 4 3 0.75 0.00168823860438942
GO:BP GO:0023056 positive regulation of signaling 0.0127778878873568 1782 4 3 0.75 0.00168350168350168
GO:BP GO:0007417 central nervous system development 0.0127778878873568 1032 19 5 0.263157894736842 0.00484496124031008
GO:BP GO:2001235 positive regulation of apoptotic signaling pathway 0.0129656734947922 129 88 4 0.0454545454545455 0.0310077519379845
GO:BP GO:0031328 positive regulation of cellular biosynthetic process 0.0135058277954159 1967 20 7 0.35 0.00355871886120996
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.0135265847835782 1645 49 11 0.224489795918367 0.00668693009118541
GO:BP GO:0032101 regulation of response to external stimulus 0.0135265847835782 1051 12 4 0.333333333333333 0.00380589914367269
GO:BP GO:0019220 regulation of phosphate metabolic process 0.0135265847835782 1645 49 11 0.224489795918367 0.00668693009118541
GO:BP GO:0050794 regulation of cellular process 0.0138000270302704 11473 22 20 0.909090909090909 0.00174322321973329
GO:BP GO:0018105 peptidyl-serine phosphorylation 0.0142128788829857 313 38 4 0.105263157894737 0.012779552715655
GO:BP GO:0000302 response to reactive oxygen species 0.01434042621825 237 50 4 0.08 0.0168776371308017
GO:BP GO:0006366 transcription by RNA polymerase II 0.0143574494080813 2723 19 8 0.421052631578947 0.00293793609988983
GO:BP GO:0006811 ion transport 0.0150986121088712 3661 21 10 0.476190476190476 0.00273149412728763
GO:BP GO:0048731 system development 0.0155961411829554 5052 21 12 0.571428571428571 0.00237529691211401
GO:BP GO:0006807 nitrogen compound metabolic process 0.0156252956447424 10078 45 34 0.755555555555556 0.00337368525501091
GO:BP GO:0032502 developmental process 0.0165873103036732 6628 21 14 0.666666666666667 0.00211225105612553
GO:BP GO:0044238 primary metabolic process 0.0167239817958252 10584 42 33 0.785714285714286 0.00311791383219955
GO:BP GO:1901019 regulation of calcium ion transmembrane transporter activity 0.0167239817958252 88 71 3 0.0422535211267606 0.0340909090909091
GO:BP GO:0018209 peptidyl-serine modification 0.0174416856755494 336 38 4 0.105263157894737 0.0119047619047619
GO:BP GO:0006469 negative regulation of protein kinase activity 0.017714839842572 251 26 3 0.115384615384615 0.0119521912350598
GO:BP GO:0009966 regulation of signal transduction 0.017714839842572 3165 14 7 0.5 0.00221169036334913
GO:BP GO:0051254 positive regulation of RNA metabolic process 0.0209749771656532 1714 19 6 0.315789473684211 0.00350058343057176
GO:BP GO:0042493 response to drug 0.021109926249536 396 18 3 0.166666666666667 0.00757575757575758
GO:BP GO:0044070 regulation of anion transport 0.0213487227227257 896 16 4 0.25 0.00446428571428571
GO:BP GO:0048585 negative regulation of response to stimulus 0.0219159212483692 1733 19 6 0.315789473684211 0.00346220427005193
GO:BP GO:0033673 negative regulation of kinase activity 0.0220406158292686 275 26 3 0.115384615384615 0.0109090909090909
GO:BP GO:2000106 regulation of leukocyte apoptotic process 0.0232595694138089 82 88 3 0.0340909090909091 0.0365853658536585
GO:BP GO:0007275 multicellular organism development 0.023860361304698 5613 42 21 0.5 0.00374131480491716
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.0242521804209799 549 14 3 0.214285714285714 0.00546448087431694
GO:BP GO:0050789 regulation of biological process 0.0246287065316983 12091 40 34 0.85 0.00281200893226367
GO:BP GO:0042542 response to hydrogen peroxide 0.0248721297761768 150 50 3 0.06 0.02
GO:BP GO:0051052 regulation of DNA metabolic process 0.0248721297761768 363 40 4 0.1 0.0110192837465565
GO:BP GO:0065007 biological regulation 0.0248721297761768 12809 26 24 0.923076923076923 0.00187368256694512
GO:BP GO:0048513 animal organ development 0.0250854863034663 3672 3 3 1 0.000816993464052288
GO:BP GO:0098656 anion transmembrane transport 0.0253643624588356 550 27 4 0.148148148148148 0.00727272727272727
GO:BP GO:0043406 positive regulation of MAP kinase activity 0.0259829434998273 234 33 3 0.0909090909090909 0.0128205128205128
GO:BP GO:0042327 positive regulation of phosphorylation 0.0271365942772393 927 95 11 0.115789473684211 0.011866235167206
GO:BP GO:0031347 regulation of defense response 0.0287182386653792 704 12 3 0.25 0.00426136363636364
GO:BP GO:0032501 multicellular organismal process 0.0288053822058791 7946 21 15 0.714285714285714 0.00188774226025673
GO:BP GO:0001934 positive regulation of protein phosphorylation 0.0294364492088224 840 19 4 0.210526315789474 0.00476190476190476
GO:BP GO:0010646 regulation of cell communication 0.0294942321936029 3543 14 7 0.5 0.00197572678521027
GO:BP GO:0071456 cellular response to hypoxia 0.0303038507722279 212 39 3 0.0769230769230769 0.0141509433962264
GO:BP GO:0023051 regulation of signaling 0.0307452608756204 3578 14 7 0.5 0.0019564002235886
GO:BP GO:0007165 signal transduction 0.0308959166342004 6309 19 12 0.631578947368421 0.0019020446980504
GO:BP GO:0008380 RNA splicing 0.0315761595644907 456 35 4 0.114285714285714 0.0087719298245614
GO:BP GO:0016043 cellular component organization 0.0325159033442539 6566 29 17 0.586206896551724 0.00258909533962839
GO:BP GO:0050778 positive regulation of immune response 0.0331304301713754 753 12 3 0.25 0.00398406374501992
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.0333247230822367 3087 44 14 0.318181818181818 0.00453514739229025
GO:BP GO:0036294 cellular response to decreased oxygen levels 0.0333745342349165 222 39 3 0.0769230769230769 0.0135135135135135
GO:BP GO:0022898 regulation of transmembrane transporter activity 0.0343783746779694 281 89 5 0.0561797752808989 0.0177935943060498
GO:BP GO:0033993 response to lipid 0.0343783746779694 918 50 7 0.14 0.00762527233115468
GO:BP GO:0045861 negative regulation of proteolysis 0.035230334137059 359 25 3 0.12 0.00835654596100279
GO:BP GO:0006793 phosphorus metabolic process 0.0352707330744049 3114 44 14 0.318181818181818 0.00449582530507386
GO:BP GO:0048856 anatomical structure development 0.0352707330744049 6106 4 4 1 0.000655093350802489
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 0.0363774205372711 512 18 3 0.166666666666667 0.005859375
GO:BP GO:0022610 biological adhesion 0.0366442086633996 1499 12 4 0.333333333333333 0.00266844563042028
GO:BP GO:0014070 response to organic cyclic compound 0.0366855071386855 967 18 4 0.222222222222222 0.00413650465356774
GO:BP GO:0002764 immune response-regulating signaling pathway 0.0366855071386855 515 18 3 0.166666666666667 0.0058252427184466
GO:BP GO:0006464 cellular protein modification process 0.0366855071386855 4041 45 17 0.377777777777778 0.00420687948527592
GO:BP GO:0036211 protein modification process 0.0366855071386855 4041 45 17 0.377777777777778 0.00420687948527592
GO:BP GO:0031669 cellular response to nutrient levels 0.0380896539510288 219 42 3 0.0714285714285714 0.0136986301369863
GO:BP GO:0098609 cell-cell adhesion 0.0391269097211424 894 11 3 0.272727272727273 0.00335570469798658
GO:BP GO:0071453 cellular response to oxygen levels 0.0392579688483044 240 39 3 0.0769230769230769 0.0125
GO:BP GO:0050776 regulation of immune response 0.0395478363146546 996 18 4 0.222222222222222 0.00401606425702811
GO:BP GO:0006996 organelle organization 0.0403452003111778 4104 19 9 0.473684210526316 0.00219298245614035
GO:BP GO:0045937 positive regulation of phosphate metabolic process 0.0408862379559769 1001 95 11 0.115789473684211 0.010989010989011
GO:BP GO:0032409 regulation of transporter activity 0.0408862379559769 297 89 5 0.0561797752808989 0.0168350168350168
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 0.0408862379559769 1001 95 11 0.115789473684211 0.010989010989011
GO:BP GO:0071887 leukocyte apoptotic process 0.0410268041180959 108 88 3 0.0340909090909091 0.0277777777777778
GO:BP GO:0001933 negative regulation of protein phosphorylation 0.0410346700258408 373 26 3 0.115384615384615 0.00804289544235925
GO:BP GO:0071840 cellular component organization or biogenesis 0.0411113664543695 6760 29 17 0.586206896551724 0.00251479289940828
GO:BP GO:0034504 protein localization to nucleus 0.0418468967160204 289 61 4 0.0655737704918033 0.013840830449827
GO:BP GO:0051707 response to other organism 0.0424269314949223 1592 12 4 0.333333333333333 0.00251256281407035
GO:BP GO:0043207 response to external biotic stimulus 0.0425604973012657 1594 12 4 0.333333333333333 0.00250941028858218
GO:BP GO:0051049 regulation of transport 0.0430588048435277 1809 16 5 0.3125 0.00276395798783858
GO:BP GO:0000209 protein polyubiquitination 0.0432451563120827 342 29 3 0.103448275862069 0.0087719298245614
GO:BP GO:0043393 regulation of protein binding 0.0437993603052474 199 90 4 0.0444444444444444 0.0201005025125628
GO:BP GO:0009607 response to biotic stimulus 0.0447253164306984 1626 12 4 0.333333333333333 0.002460024600246
GO:BP GO:0009605 response to external stimulus 0.0451846183529595 2944 18 7 0.388888888888889 0.00237771739130435
GO:BP GO:0046777 protein autophosphorylation 0.0451846183529595 240 42 3 0.0714285714285714 0.0125
GO:BP GO:0031668 cellular response to extracellular stimulus 0.0482932933893813 248 42 3 0.0714285714285714 0.0120967741935484
GO:BP GO:0051276 chromosome organization 0.0493487229201444 1258 69 10 0.144927536231884 0.00794912559618442
GO:CC GO:0070062 extracellular exosome 1.22562068523892e-09 2176 14 13 0.928571428571429 0.00597426470588235
GO:CC GO:0043230 extracellular organelle 1.22562068523892e-09 2263 14 13 0.928571428571429 0.00574458683163942
GO:CC GO:1903561 extracellular vesicle 1.22562068523892e-09 2261 14 13 0.928571428571429 0.00574966828836798
GO:CC GO:1904813 ficolin-1-rich granule lumen 8.72988021488313e-09 124 13 6 0.461538461538462 0.0483870967741935
GO:CC GO:0101002 ficolin-1-rich granule 7.61630098477464e-08 184 13 6 0.461538461538462 0.0326086956521739
GO:CC GO:0101031 chaperone complex 1.27914596664368e-07 27 40 5 0.125 0.185185185185185
GO:CC GO:0008180 COP9 signalosome 1.81661025450142e-07 35 12 4 0.333333333333333 0.114285714285714
GO:CC GO:0005615 extracellular space 1.81661025450142e-07 3594 14 13 0.928571428571429 0.00361713967723984
GO:CC GO:0031982 vesicle 7.3403416020524e-07 4055 14 13 0.928571428571429 0.0032059186189889
GO:CC GO:0005576 extracellular region 3.00893223362596e-06 4567 14 13 0.928571428571429 0.00284650755419312
GO:CC GO:0005829 cytosol 4.8677983127933e-06 5303 20 17 0.85 0.00320573260418631
GO:CC GO:0031974 membrane-enclosed lumen 5.66524211726187e-06 5565 45 30 0.666666666666667 0.00539083557951483
GO:CC GO:0043233 organelle lumen 5.66524211726187e-06 5565 45 30 0.666666666666667 0.00539083557951483
GO:CC GO:0016234 inclusion body 9.1117977160996e-06 76 16 4 0.25 0.0526315789473684
GO:CC GO:0048471 perinuclear region of cytoplasm 9.61325099136261e-06 735 35 10 0.285714285714286 0.0136054421768707
GO:CC GO:0030141 secretory granule 9.61325099136261e-06 851 13 7 0.538461538461538 0.0082256169212691
GO:CC GO:0005654 nucleoplasm 9.61325099136261e-06 4102 50 27 0.54 0.00658215504631887
GO:CC GO:0070013 intracellular organelle lumen 9.61325099136261e-06 5402 45 29 0.644444444444444 0.00536838208071085
GO:CC GO:0031981 nuclear lumen 2.01744572870457e-05 4444 73 36 0.493150684931507 0.0081008100810081
GO:CC GO:0099503 secretory vesicle 2.51230252211879e-05 1020 13 7 0.538461538461538 0.00686274509803922
GO:CC GO:0072562 blood microparticle 2.80822731658813e-05 140 13 4 0.307692307692308 0.0285714285714286
GO:CC GO:0005634 nucleus 3.0103548384015e-05 7592 69 47 0.681159420289855 0.00619072708113804
GO:CC GO:0016235 aggresome 4.20943879242738e-05 35 16 3 0.1875 0.0857142857142857
GO:CC GO:0097708 intracellular vesicle 4.8997916861152e-05 2428 13 9 0.692307692307692 0.00370675453047776
GO:CC GO:0031410 cytoplasmic vesicle 4.8997916861152e-05 2424 13 9 0.692307692307692 0.00371287128712871
GO:CC GO:0005739 mitochondrion 7.83788901870643e-05 1673 14 8 0.571428571428571 0.00478182904961148
GO:CC GO:0005737 cytoplasm 0.000100371884779164 11911 25 25 1 0.00209890017630761
GO:CC GO:0005814 centriole 0.000328888754299954 142 9 3 0.333333333333333 0.0211267605633803
GO:CC GO:0043005 neuron projection 0.000406684355762851 1380 20 8 0.4 0.00579710144927536
GO:CC GO:0042470 melanosome 0.000406684355762851 105 13 3 0.230769230769231 0.0285714285714286
GO:CC GO:0048770 pigment granule 0.000406684355762851 105 13 3 0.230769230769231 0.0285714285714286
GO:CC GO:0034774 secretory granule lumen 0.000439928977823486 320 13 4 0.307692307692308 0.0125
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.00044737487555518 324 13 4 0.307692307692308 0.0123456790123457
GO:CC GO:0031983 vesicle lumen 0.00044737487555518 326 13 4 0.307692307692308 0.0122699386503067
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.000742104001690172 5338 65 33 0.507692307692308 0.00618209067066317
GO:CC GO:0043228 non-membrane-bounded organelle 0.00074697419568084 5346 65 33 0.507692307692308 0.00617283950617284
GO:CC GO:0005925 focal adhesion 0.0010773281583195 420 13 4 0.307692307692308 0.00952380952380952
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.00108881642378582 11296 54 45 0.833333333333333 0.00398371104815864
GO:CC GO:0015630 microtubule cytoskeleton 0.00108881642378582 1307 9 5 0.555555555555556 0.00382555470543229
GO:CC GO:0030055 cell-substrate junction 0.00108881642378582 427 13 4 0.307692307692308 0.00936768149882904
GO:CC GO:0030139 endocytic vesicle 0.00141182362792843 306 19 4 0.210526315789474 0.0130718954248366
GO:CC GO:0044297 cell body 0.00198836330469472 592 20 5 0.25 0.00844594594594595
GO:CC GO:0030018 Z disc 0.00214796831033346 126 50 4 0.08 0.0317460317460317
GO:CC GO:0031674 I band 0.00293312367700373 139 50 4 0.08 0.0287769784172662
GO:CC GO:0032991 protein-containing complex 0.00304954712557086 5548 13 10 0.769230769230769 0.00180245133381399
GO:CC GO:0097447 dendritic tree 0.00399765966054778 640 13 4 0.307692307692308 0.00625
GO:CC GO:0030425 dendrite 0.00399765966054778 638 13 4 0.307692307692308 0.00626959247648903
GO:CC GO:0140513 nuclear protein-containing complex 0.00410077330544529 1249 18 6 0.333333333333333 0.00480384307445957
GO:CC GO:0030424 axon 0.00433026407015861 660 13 4 0.307692307692308 0.00606060606060606
GO:CC GO:0043229 intracellular organelle 0.00528873673283573 12491 42 37 0.880952380952381 0.00296213273556961
GO:CC GO:0150034 distal axon 0.00546941126092459 308 13 3 0.230769230769231 0.00974025974025974
GO:CC GO:0120025 plasma membrane bounded cell projection 0.00614181925963596 2229 20 8 0.4 0.00358905338716913
GO:CC GO:0036477 somatodendritic compartment 0.00634078104713944 871 19 5 0.263157894736842 0.00574052812858783
GO:CC GO:0030054 cell junction 0.00634078104713944 2105 3 3 1 0.00142517814726841
GO:CC GO:0043025 neuronal cell body 0.00693220194755093 518 19 4 0.210526315789474 0.00772200772200772
GO:CC GO:0070161 anchoring junction 0.00693220194755093 836 6 3 0.5 0.00358851674641148
GO:CC GO:0042995 cell projection 0.0072761035762231 2330 20 8 0.4 0.00343347639484979
GO:CC GO:0005856 cytoskeleton 0.00764337456308756 2332 16 7 0.4375 0.00300171526586621
GO:CC GO:0012505 endomembrane system 0.0077298485896112 4640 14 9 0.642857142857143 0.00193965517241379
GO:CC GO:0005622 intracellular anatomical structure 0.00803143030314358 14790 25 25 1 0.00169033130493577
GO:CC GO:0043227 membrane-bounded organelle 0.00803143030314358 12858 16 16 1 0.00124436148701198
GO:CC GO:0005886 plasma membrane 0.00811318032214062 5681 23 14 0.608695652173913 0.00246435486710086
GO:CC GO:0030017 sarcomere 0.00854049694292461 208 50 4 0.08 0.0192307692307692
GO:CC GO:0030016 myofibril 0.0114020821133271 231 24 3 0.125 0.012987012987013
GO:CC GO:0043292 contractile fiber 0.0125418840353572 240 24 3 0.125 0.0125
GO:CC GO:0071944 cell periphery 0.0154465946346894 6169 25 15 0.6 0.00243151240071324
GO:CC GO:0005730 nucleolus 0.0160571997145075 955 64 9 0.140625 0.00942408376963351
GO:CC GO:0043226 organelle 0.0238169000688172 14008 16 16 1 0.00114220445459737
GO:CC GO:0140535 intracellular protein-containing complex 0.0238169000688172 767 20 4 0.2 0.00521512385919166
GO:CC GO:0005759 mitochondrial matrix 0.0291046694085456 479 73 6 0.0821917808219178 0.0125260960334029
GO:CC GO:0005783 endoplasmic reticulum 0.0293530371410823 1982 19 6 0.315789473684211 0.00302724520686176
GO:CC GO:0000323 lytic vacuole 0.0301750326069419 712 13 3 0.230769230769231 0.00421348314606742
GO:CC GO:0005764 lysosome 0.0301750326069419 712 13 3 0.230769230769231 0.00421348314606742
GO:CC GO:0016020 membrane 0.0310999110996823 9838 25 19 0.76 0.00193128684692011
GO:CC GO:0005819 spindle 0.0342159802740404 387 69 5 0.072463768115942 0.0129198966408269
GO:CC GO:0018995 host cellular component 0.0343644407849103 198 48 3 0.0625 0.0151515151515152
GO:CC GO:0043657 host cell 0.0343644407849103 198 48 3 0.0625 0.0151515151515152
GO:CC GO:0099512 supramolecular fiber 0.0366395473548522 993 50 7 0.14 0.00704934541792548
GO:CC GO:0005768 endosome 0.0368792017421606 987 19 4 0.210526315789474 0.00405268490374873
GO:CC GO:0099081 supramolecular polymer 0.0372395801000599 1001 50 7 0.14 0.00699300699300699
GO:CC GO:0005773 vacuole 0.0387041396678257 810 13 3 0.230769230769231 0.0037037037037037
GO:CC GO:0009986 cell surface 0.0396402553130134 899 12 3 0.25 0.00333704115684093
GO:CC GO:0098562 cytoplasmic side of membrane 0.0406399623928185 194 54 3 0.0555555555555556 0.0154639175257732
GO:CC GO:0031966 mitochondrial membrane 0.0439771494070154 746 27 4 0.148148148148148 0.00536193029490617
GO:CC GO:0031975 envelope 0.0439771494070154 1237 53 8 0.150943396226415 0.00646725949878739
GO:CC GO:0031967 organelle envelope 0.0439771494070154 1237 53 8 0.150943396226415 0.00646725949878739
GO:CC GO:0099080 supramolecular complex 0.0445752661686537 1323 50 8 0.16 0.00604686318972033
GO:CC GO:0005740 mitochondrial envelope 0.0495666393407339 797 27 4 0.148148148148148 0.00501882057716437
GO:MF GO:0051082 unfolded protein binding 5.59053652470088e-24 112 73 19 0.26027397260274 0.169642857142857
GO:MF GO:0044183 protein folding chaperone 1.54373540813912e-17 35 13 8 0.615384615384615 0.228571428571429
GO:MF GO:0031072 heat shock protein binding 8.20953564631496e-16 127 26 11 0.423076923076923 0.0866141732283465
GO:MF GO:0031625 ubiquitin protein ligase binding 2.12700652393187e-15 296 20 12 0.6 0.0405405405405405
GO:MF GO:0044389 ubiquitin-like protein ligase binding 3.47593633395021e-15 314 20 12 0.6 0.0382165605095541
GO:MF GO:0051087 chaperone binding 2.52672136201115e-13 103 24 9 0.375 0.087378640776699
GO:MF GO:0055131 C3HC4-type RING finger domain binding 1.59022371177077e-10 6 14 4 0.285714285714286 0.666666666666667
GO:MF GO:0060590 ATPase regulator activity 7.34858080738501e-10 44 24 6 0.25 0.136363636363636
GO:MF GO:0030554 adenyl nucleotide binding 2.20198231623459e-08 1578 17 12 0.705882352941177 0.00760456273764259
GO:MF GO:0019899 enzyme binding 3.16936758882917e-08 2074 20 14 0.7 0.00675024108003857
GO:MF GO:0051787 misfolded protein binding 3.47874906600294e-08 28 73 6 0.0821917808219178 0.214285714285714
GO:MF GO:0017076 purine nucleotide binding 1.72623347488682e-07 1933 17 12 0.705882352941177 0.00620796689084325
GO:MF GO:0005524 ATP binding 1.98364602693467e-07 1501 17 11 0.647058823529412 0.00732844770153231
GO:MF GO:0032559 adenyl ribonucleotide binding 2.86139544978809e-07 1565 17 11 0.647058823529412 0.00702875399361022
GO:MF GO:1901265 nucleoside phosphate binding 4.93024690820968e-07 2172 17 12 0.705882352941177 0.00552486187845304
GO:MF GO:0000166 nucleotide binding 4.93024690820968e-07 2171 17 12 0.705882352941177 0.00552740672501152
GO:MF GO:0001671 ATPase activator activity 5.76229471826537e-07 25 24 4 0.166666666666667 0.16
GO:MF GO:0035639 purine ribonucleoside triphosphate binding 1.25894865361044e-06 1847 14 10 0.714285714285714 0.00541418516513265
GO:MF GO:0032555 purine ribonucleotide binding 1.71453030445469e-06 1918 14 10 0.714285714285714 0.00521376433785193
GO:MF GO:0032553 ribonucleotide binding 1.77296564785323e-06 1935 14 10 0.714285714285714 0.00516795865633075
GO:MF GO:0036094 small molecule binding 1.91246442706301e-06 2506 17 12 0.705882352941177 0.00478850758180367
GO:MF GO:0023026 MHC class II protein complex binding 3.04485563964876e-06 17 13 3 0.230769230769231 0.176470588235294
GO:MF GO:0030234 enzyme regulator activity 3.45833703476895e-06 1248 25 11 0.44 0.00881410256410256
GO:MF GO:0019904 protein domain specific binding 5.51712180869348e-06 710 20 8 0.4 0.0112676056338028
GO:MF GO:0097367 carbohydrate derivative binding 6.69080058731584e-06 2285 14 10 0.714285714285714 0.00437636761487965
GO:MF GO:0016887 ATPase activity 6.69080058731584e-06 488 13 6 0.461538461538462 0.0122950819672131
GO:MF GO:0023023 MHC protein complex binding 8.36466210937453e-06 25 13 3 0.230769230769231 0.12
GO:MF GO:0042826 histone deacetylase binding 8.80650805879139e-06 116 12 4 0.333333333333333 0.0344827586206897
GO:MF GO:0003723 RNA binding 8.80650805879139e-06 1943 13 9 0.692307692307692 0.00463201235203294
GO:MF GO:0043168 anion binding 9.92767839449374e-06 2418 14 10 0.714285714285714 0.00413564929693962
GO:MF GO:0097718 disordered domain specific binding 1.45459094294574e-05 34 12 3 0.25 0.0882352941176471
GO:MF GO:0098772 molecular function regulator 2.8599868925256e-05 2363 25 13 0.52 0.00550148116800677
GO:MF GO:0060589 nucleoside-triphosphatase regulator activity 3.69264930835432e-05 530 24 7 0.291666666666667 0.0132075471698113
GO:MF GO:0045296 cadherin binding 7.18799258045758e-05 333 16 5 0.3125 0.015015015015015
GO:MF GO:0070182 DNA polymerase binding 7.80282508082018e-05 18 40 3 0.075 0.166666666666667
GO:MF GO:0017111 nucleoside-triphosphatase activity 0.000133886935355477 872 13 6 0.461538461538462 0.00688073394495413
GO:MF GO:0016462 pyrophosphatase activity 0.000162689231334179 928 13 6 0.461538461538462 0.00646551724137931
GO:MF GO:1901363 heterocyclic compound binding 0.000162689231334179 6228 18 15 0.833333333333333 0.00240847784200385
GO:MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.000162689231334179 930 13 6 0.461538461538462 0.00645161290322581
GO:MF GO:0016817 hydrolase activity, acting on acid anhydrides 0.000162689231334179 930 13 6 0.461538461538462 0.00645161290322581
GO:MF GO:0097159 organic cyclic compound binding 0.000184030225582405 6309 18 15 0.833333333333333 0.00237755587256301
GO:MF GO:0001664 G protein-coupled receptor binding 0.000405649783956886 292 14 4 0.285714285714286 0.0136986301369863
GO:MF GO:0050839 cell adhesion molecule binding 0.000527145643784034 546 16 5 0.3125 0.00915750915750916
GO:MF GO:0003676 nucleic acid binding 0.00335545070125198 4276 13 9 0.692307692307692 0.00210477081384471
GO:MF GO:0008047 enzyme activator activity 0.00358876735190232 540 24 5 0.208333333333333 0.00925925925925926
GO:MF GO:0005515 protein binding 0.0041199555147187 14767 42 41 0.976190476190476 0.00277646102796777
GO:MF GO:0044877 protein-containing complex binding 0.00593923303089951 1287 18 6 0.333333333333333 0.00466200466200466
GO:MF GO:0043167 ion binding 0.0080678600580434 6057 15 11 0.733333333333333 0.00181608056793792
GO:MF GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 0.0121465862036268 281 18 3 0.166666666666667 0.0106761565836299
GO:MF GO:0099106 ion channel regulator activity 0.0132079216134631 120 89 4 0.0449438202247191 0.0333333333333333
GO:MF GO:0042803 protein homodimerization activity 0.0224278571122923 676 20 4 0.2 0.00591715976331361
GO:MF GO:0016787 hydrolase activity 0.0226961217219785 2615 13 6 0.461538461538462 0.00229445506692161
GO:MF GO:0016247 channel regulator activity 0.0237548385182432 149 89 4 0.0449438202247191 0.0268456375838926
GO:MF GO:0005102 signaling receptor binding 0.0240182726777134 1672 14 5 0.357142857142857 0.00299043062200957
GO:MF GO:0140297 DNA-binding transcription factor binding 0.0242438536117223 391 18 3 0.166666666666667 0.00767263427109974
GO:MF GO:0005516 calmodulin binding 0.0294401646134795 204 71 4 0.0563380281690141 0.0196078431372549
GO:MF GO:0019901 protein kinase binding 0.0302065342987639 673 12 3 0.25 0.00445765230312036
GO:MF GO:0019900 kinase binding 0.0377025576915956 752 12 3 0.25 0.00398936170212766
GO:MF GO:0042802 identical protein binding 0.0417974912502383 2067 24 7 0.291666666666667 0.00338655055636188
HPA HPA:0060103 bronchus; respiratory epithelial cells[High] 0.00841155221573575 1890 12 9 0.75 0.00476190476190476
HPA HPA:0330222 oral mucosa; squamous epithelial cells[≥Medium] 0.0204447731560178 4254 27 20 0.740740740740741 0.00470145745181006
HPA HPA:0100123 cerebral cortex; glial cells[High] 0.0204447731560178 683 19 7 0.368421052631579 0.0102489019033675
HPA HPA:0340462 ovary; ovarian stroma cells[≥Medium] 0.0204447731560178 2002 20 11 0.55 0.00549450549450549
HPA HPA:0500113 soft tissue 1; chondrocytes[High] 0.0204447731560178 296 14 4 0.285714285714286 0.0135135135135135
HPA HPA:0470683 skin 2; epidermal cells[High] 0.0204447731560178 1346 20 9 0.45 0.00668647845468053
HPA HPA:0470682 skin 2; epidermal cells[≥Medium] 0.0204447731560178 4735 27 21 0.777777777777778 0.0044350580781415
HPA HPA:0110222 cervix, uterine; squamous epithelial cells[≥Medium] 0.0204447731560178 3617 27 18 0.666666666666667 0.00497649986176389
HPA HPA:0570763 testis; pachytene spermatocytes[High] 0.0204447731560178 822 3 3 1 0.00364963503649635
HPA HPA:0330223 oral mucosa; squamous epithelial cells[High] 0.0208677696335603 1112 20 8 0.4 0.00719424460431655
HPA HPA:0110223 cervix, uterine; squamous epithelial cells[High] 0.0239983195821773 986 3 3 1 0.00304259634888438
HPA HPA:0620222 vagina; squamous epithelial cells[≥Medium] 0.0239983195821773 3945 26 18 0.692307692307692 0.00456273764258555
HPA HPA:0190222 esophagus; squamous epithelial cells[≥Medium] 0.0239983195821773 4937 27 21 0.777777777777778 0.00425359530078995
HPA HPA:0190223 esophagus; squamous epithelial cells[High] 0.0276056960393023 1596 7 5 0.714285714285714 0.0031328320802005
HPA HPA:0210053 fallopian tube; glandular cells[High] 0.0276056960393023 1728 15 8 0.533333333333333 0.00462962962962963
HPA HPA:0460642 skin 1; Langerhans[≥Medium] 0.0276056960393023 3123 16 11 0.6875 0.00352225424271534
HPA HPA:0460672 skin 1; melanocytes[≥Medium] 0.0276056960393023 3700 16 12 0.75 0.00324324324324324
HPA HPA:0610833 urinary bladder; urothelial cells[High] 0.0286860972309174 1969 20 10 0.5 0.00507872016251905
HPA HPA:0210052 fallopian tube; glandular cells[≥Medium] 0.0319673207416114 5023 12 11 0.916666666666667 0.00218992633884133
HPA HPA:0570753 testis; elongated or late spermatids[High] 0.0319673207416114 599 10 4 0.4 0.00667779632721202
HPA HPA:0291162 liver; cholangiocytes[≥Medium] 0.0366321221039604 1910 12 7 0.583333333333333 0.00366492146596859
HPA HPA:0060102 bronchus; respiratory epithelial cells[≥Medium] 0.0394972267485864 5184 12 11 0.916666666666667 0.00212191358024691
HPA HPA:0340461 ovary; ovarian stroma cells[≥Low] 0.0394972267485864 3894 26 17 0.653846153846154 0.00436569080636877
HPA HPA:0510702 soft tissue 2; peripheral nerve[≥Medium] 0.0394972267485864 1477 19 8 0.421052631578947 0.00541638456330399
HPA HPA:0390052 prostate; glandular cells[≥Medium] 0.0403954742036407 4699 16 13 0.8125 0.00276654607363269
HPA HPA:0080121 caudate; glial cells[≥Low] 0.0480641616304187 4464 24 17 0.708333333333333 0.00380824372759857
HPA HPA:0600222 tonsil; squamous epithelial cells[≥Medium] 0.0480641616304187 4851 16 13 0.8125 0.00267985982271697
HPA HPA:0180052 epididymis; glandular cells[≥Medium] 0.0480641616304187 5560 16 14 0.875 0.00251798561151079
HPA HPA:0570781 testis; preleptotene spermatocytes[≥Low] 0.0480641616304187 1636 3 3 1 0.00183374083129584
HPA HPA:0570762 testis; pachytene spermatocytes[≥Medium] 0.0480641616304187 1658 3 3 1 0.00180940892641737
HPA HPA:0390053 prostate; glandular cells[High] 0.0480641616304187 1284 14 6 0.428571428571429 0.00467289719626168
KEGG KEGG:04141 Protein processing in endoplasmic reticulum 1.68455215687722e-10 170 14 9 0.642857142857143 0.0529411764705882
KEGG KEGG:04612 Antigen processing and presentation 3.47932470336806e-08 69 13 6 0.461538461538462 0.0869565217391304
KEGG KEGG:05134 Legionellosis 2.93247436999173e-07 57 22 6 0.272727272727273 0.105263157894737
KEGG KEGG:04915 Estrogen signaling pathway 3.24627646315707e-07 137 18 7 0.388888888888889 0.0510948905109489
KEGG KEGG:04213 Longevity regulating pathway - multiple species 3.34065957122301e-05 62 73 7 0.0958904109589041 0.112903225806452
KEGG KEGG:05162 Measles 0.000226136325197237 139 18 5 0.277777777777778 0.0359712230215827
KEGG KEGG:05145 Toxoplasmosis 0.000390723482181189 109 13 4 0.307692307692308 0.036697247706422
KEGG KEGG:04010 MAPK signaling pathway 0.00048192153185096 294 18 6 0.333333333333333 0.0204081632653061
KEGG KEGG:03040 Spliceosome 0.00106627699982897 150 13 4 0.307692307692308 0.0266666666666667
KEGG KEGG:04144 Endocytosis 0.00643661510251621 252 13 4 0.307692307692308 0.0158730158730159
KEGG KEGG:04137 Mitophagy - animal 0.00643661510251621 68 19 3 0.157894736842105 0.0441176470588235
KEGG KEGG:05020 Prion disease 0.00798666290767033 273 13 4 0.307692307692308 0.0146520146520147
KEGG KEGG:04657 IL-17 signaling pathway 0.010512865367667 92 18 3 0.166666666666667 0.0326086956521739
KEGG KEGG:04659 Th17 cell differentiation 0.01391865719358 104 18 3 0.166666666666667 0.0288461538461538
KEGG KEGG:05418 Fluid shear stress and atherosclerosis 0.0291414227800983 138 18 3 0.166666666666667 0.0217391304347826
MIRNA MIRNA:hsa-miR-106a-5p hsa-miR-106a-5p 0.00257641385219558 709 51 12 0.235294117647059 0.0169252468265162
MIRNA MIRNA:hsa-miR-16-5p hsa-miR-16-5p 0.00257641385219558 1556 18 10 0.555555555555556 0.006426735218509
MIRNA MIRNA:hsa-miR-4796-3p hsa-miR-4796-3p 0.00257641385219558 285 51 8 0.156862745098039 0.0280701754385965
MIRNA MIRNA:hsa-miR-526b-3p hsa-miR-526b-3p 0.00293610852456168 635 51 11 0.215686274509804 0.0173228346456693
MIRNA MIRNA:hsa-miR-3609 hsa-miR-3609 0.00293610852456168 319 51 8 0.156862745098039 0.0250783699059561
MIRNA MIRNA:hsa-miR-548ah-5p hsa-miR-548ah-5p 0.00293610852456168 318 51 8 0.156862745098039 0.0251572327044025
MIRNA MIRNA:hsa-miR-4724-5p hsa-miR-4724-5p 0.00362825200487038 98 24 4 0.166666666666667 0.0408163265306122
MIRNA MIRNA:hsa-miR-365b-3p hsa-miR-365b-3p 0.00413363095133054 86 29 4 0.137931034482759 0.0465116279069767
MIRNA MIRNA:hsa-miR-17-5p hsa-miR-17-5p 0.00458941386778608 1174 51 14 0.274509803921569 0.0119250425894378
MIRNA MIRNA:hsa-miR-548o-5p hsa-miR-548o-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548ak hsa-miR-548ak 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548i hsa-miR-548i 0.0058064371570521 201 60 6 0.1 0.0298507462686567
MIRNA MIRNA:hsa-miR-548w hsa-miR-548w 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548ae-5p hsa-miR-548ae-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-20b-5p hsa-miR-20b-5p 0.0058064371570521 911 51 12 0.235294117647059 0.013172338090011
MIRNA MIRNA:hsa-miR-324-3p hsa-miR-324-3p 0.0058064371570521 336 13 4 0.307692307692308 0.0119047619047619
MIRNA MIRNA:hsa-miR-548y hsa-miR-548y 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548j-5p hsa-miR-548j-5p 0.0058064371570521 199 60 6 0.1 0.0301507537688442
MIRNA MIRNA:hsa-miR-365a-3p hsa-miR-365a-3p 0.0058064371570521 123 29 4 0.137931034482759 0.032520325203252
MIRNA MIRNA:hsa-miR-548ab hsa-miR-548ab 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548c-5p hsa-miR-548c-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-106b-5p hsa-miR-106b-5p 0.0058064371570521 1084 51 13 0.254901960784314 0.0119926199261993
MIRNA MIRNA:hsa-miR-548a-5p hsa-miR-548a-5p 0.0058064371570521 199 60 6 0.1 0.0301507537688442
MIRNA MIRNA:hsa-miR-548d-5p hsa-miR-548d-5p 0.0058064371570521 201 60 6 0.1 0.0298507462686567
MIRNA MIRNA:hsa-miR-548ad-5p hsa-miR-548ad-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548bb-5p hsa-miR-548bb-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548am-5p hsa-miR-548am-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-10a-5p hsa-miR-10a-5p 0.0058064371570521 461 4 3 0.75 0.00650759219088937
MIRNA MIRNA:hsa-miR-548ay-5p hsa-miR-548ay-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-221-3p hsa-miR-221-3p 0.0058064371570521 366 29 6 0.206896551724138 0.0163934426229508
MIRNA MIRNA:hsa-miR-548au-5p hsa-miR-548au-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548ap-5p hsa-miR-548ap-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548as-5p hsa-miR-548as-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-34c-5p hsa-miR-34c-5p 0.0058064371570521 171 8 3 0.375 0.0175438596491228
MIRNA MIRNA:hsa-miR-30a-5p hsa-miR-30a-5p 0.0058064371570521 730 31 8 0.258064516129032 0.010958904109589
MIRNA MIRNA:hsa-miR-548b-5p hsa-miR-548b-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548ar-5p hsa-miR-548ar-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548aq-5p hsa-miR-548aq-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-548h-5p hsa-miR-548h-5p 0.0058064371570521 198 60 6 0.1 0.0303030303030303
MIRNA MIRNA:hsa-miR-519d-3p hsa-miR-519d-3p 0.0058064371570521 900 51 12 0.235294117647059 0.0133333333333333
MIRNA MIRNA:hsa-miR-559 hsa-miR-559 0.00594807686241127 203 60 6 0.1 0.0295566502463054
MIRNA MIRNA:hsa-miR-93-5p hsa-miR-93-5p 0.00605786141882747 1213 51 13 0.254901960784314 0.010717230008244
MIRNA MIRNA:hsa-miR-20a-5p hsa-miR-20a-5p 0.00677946093120424 1064 51 12 0.235294117647059 0.0112781954887218
MIRNA MIRNA:hsa-miR-26b-5p hsa-miR-26b-5p 0.00677946093120424 1852 31 12 0.387096774193548 0.00647948164146868
MIRNA MIRNA:hsa-miR-582-5p hsa-miR-582-5p 0.0107023545231282 149 14 3 0.214285714285714 0.0201342281879195
MIRNA MIRNA:hsa-miR-331-3p hsa-miR-331-3p 0.0118804262885161 403 36 6 0.166666666666667 0.0148883374689826
MIRNA MIRNA:hsa-miR-101-3p hsa-miR-101-3p 0.0139697807977935 391 53 7 0.132075471698113 0.0179028132992327
MIRNA MIRNA:hsa-miR-5581-3p hsa-miR-5581-3p 0.0158868202976467 56 42 3 0.0714285714285714 0.0535714285714286
MIRNA MIRNA:hsa-miR-429 hsa-miR-429 0.0171873043138451 151 38 4 0.105263157894737 0.0264900662251656
MIRNA MIRNA:hsa-miR-548l hsa-miR-548l 0.0179349439764038 171 60 5 0.0833333333333333 0.0292397660818713
MIRNA MIRNA:hsa-miR-633 hsa-miR-633 0.0179349439764038 81 31 3 0.0967741935483871 0.037037037037037
MIRNA MIRNA:hsa-miR-378a-3p hsa-miR-378a-3p 0.0183569325269464 165 36 4 0.111111111111111 0.0242424242424242
MIRNA MIRNA:hsa-miR-1226-3p hsa-miR-1226-3p 0.0186247682634887 226 12 3 0.25 0.0132743362831858
MIRNA MIRNA:hsa-miR-4645-3p hsa-miR-4645-3p 0.0200173641852929 71 38 3 0.0789473684210526 0.0422535211267606
MIRNA MIRNA:hsa-miR-3174 hsa-miR-3174 0.0201460821551422 107 58 4 0.0689655172413793 0.0373831775700935
MIRNA MIRNA:hsa-miR-4309 hsa-miR-4309 0.0210547543993827 118 24 3 0.125 0.0254237288135593
MIRNA MIRNA:hsa-miR-3198 hsa-miR-3198 0.021301062275844 120 24 3 0.125 0.025
MIRNA MIRNA:hsa-miR-3143 hsa-miR-3143 0.021301062275844 92 31 3 0.0967741935483871 0.0326086956521739
MIRNA MIRNA:hsa-miR-296-3p hsa-miR-296-3p 0.0223733513269145 255 12 3 0.25 0.0117647058823529
MIRNA MIRNA:hsa-miR-130b-3p hsa-miR-130b-3p 0.0229410009918831 571 31 6 0.193548387096774 0.010507880910683
MIRNA MIRNA:hsa-miR-153-3p hsa-miR-153-3p 0.0251928452815015 84 81 4 0.0493827160493827 0.0476190476190476
MIRNA MIRNA:hsa-miR-335-3p hsa-miR-335-3p 0.0261379058778533 302 11 3 0.272727272727273 0.00993377483443709
MIRNA MIRNA:hsa-miR-30c-5p hsa-miR-30c-5p 0.0261379058778533 519 35 6 0.171428571428571 0.0115606936416185
MIRNA MIRNA:hsa-miR-4257 hsa-miR-4257 0.0261775463573748 381 9 3 0.333333333333333 0.0078740157480315
MIRNA MIRNA:hsa-miR-200b-3p hsa-miR-200b-3p 0.0261775463573748 185 38 4 0.105263157894737 0.0216216216216216
MIRNA MIRNA:hsa-miR-15a-5p hsa-miR-15a-5p 0.0270125610501187 717 18 5 0.277777777777778 0.00697350069735007
MIRNA MIRNA:hsa-miR-224-5p hsa-miR-224-5p 0.0290779036726052 132 93 5 0.0537634408602151 0.0378787878787879
MIRNA MIRNA:hsa-miR-3591-5p hsa-miR-3591-5p 0.0304224929753139 97 35 3 0.0857142857142857 0.0309278350515464
MIRNA MIRNA:hsa-miR-26a-5p hsa-miR-26a-5p 0.033350548877648 457 42 6 0.142857142857143 0.0131291028446389
MIRNA MIRNA:hsa-miR-5697 hsa-miR-5697 0.0333936836038018 171 21 3 0.142857142857143 0.0175438596491228
MIRNA MIRNA:hsa-miR-100-5p hsa-miR-100-5p 0.0341420601269058 250 52 5 0.0961538461538462 0.02
MIRNA MIRNA:hsa-miR-3974 hsa-miR-3974 0.0350873376287261 67 54 3 0.0555555555555556 0.0447761194029851
MIRNA MIRNA:hsa-miR-378a-5p hsa-miR-378a-5p 0.0359109510086716 382 88 8 0.0909090909090909 0.0209424083769634
MIRNA MIRNA:hsa-miR-340-5p hsa-miR-340-5p 0.0367829178135894 340 58 6 0.103448275862069 0.0176470588235294
MIRNA MIRNA:hsa-miR-944 hsa-miR-944 0.0367829178135894 121 31 3 0.0967741935483871 0.0247933884297521
MIRNA MIRNA:hsa-miR-32-3p hsa-miR-32-3p 0.0367829178135894 123 31 3 0.0967741935483871 0.024390243902439
MIRNA MIRNA:hsa-miR-548n hsa-miR-548n 0.0367829178135894 259 52 5 0.0961538461538462 0.0193050193050193
MIRNA MIRNA:hsa-miR-519b-3p hsa-miR-519b-3p 0.0367829178135894 342 24 4 0.166666666666667 0.0116959064327485
MIRNA MIRNA:hsa-miR-200c-3p hsa-miR-200c-3p 0.0367829178135894 214 38 4 0.105263157894737 0.0186915887850467
MIRNA MIRNA:hsa-miR-519a-3p hsa-miR-519a-3p 0.0370384901877234 347 24 4 0.166666666666667 0.0115273775216138
MIRNA MIRNA:hsa-miR-519c-3p hsa-miR-519c-3p 0.0370384901877234 348 24 4 0.166666666666667 0.0114942528735632
MIRNA MIRNA:hsa-miR-4465 hsa-miR-4465 0.0385147184421702 190 21 3 0.142857142857143 0.0157894736842105
MIRNA MIRNA:hsa-miR-1297 hsa-miR-1297 0.0399652965073706 194 21 3 0.142857142857143 0.0154639175257732
MIRNA MIRNA:hsa-miR-448 hsa-miR-448 0.0405549847228126 97 87 4 0.0459770114942529 0.0412371134020619
MIRNA MIRNA:hsa-miR-3148 hsa-miR-3148 0.0429207386744268 243 36 4 0.111111111111111 0.0164609053497942
MIRNA MIRNA:hsa-miR-8054 hsa-miR-8054 0.0429207386744268 147 60 4 0.0666666666666667 0.0272108843537415
MIRNA MIRNA:hsa-miR-197-3p hsa-miR-197-3p 0.0429207386744268 407 11 3 0.272727272727273 0.00737100737100737
MIRNA MIRNA:hsa-miR-548av-5p hsa-miR-548av-5p 0.0429207386744268 147 60 4 0.0666666666666667 0.0272108843537415
MIRNA MIRNA:hsa-miR-33a-5p hsa-miR-33a-5p 0.0429207386744268 179 49 4 0.0816326530612245 0.0223463687150838
MIRNA MIRNA:hsa-miR-548k hsa-miR-548k 0.0429207386744268 147 60 4 0.0666666666666667 0.0272108843537415
MIRNA MIRNA:hsa-miR-130b-5p hsa-miR-130b-5p 0.0429207386744268 342 13 3 0.230769230769231 0.0087719298245614
MIRNA MIRNA:hsa-miR-205-5p hsa-miR-205-5p 0.0446895060749026 182 81 5 0.0617283950617284 0.0274725274725275
MIRNA MIRNA:hsa-miR-744-5p hsa-miR-744-5p 0.0470272039200607 435 11 3 0.272727272727273 0.00689655172413793
MIRNA MIRNA:hsa-miR-186-5p hsa-miR-186-5p 0.0470272039200607 749 40 7 0.175 0.00934579439252336
MIRNA MIRNA:hsa-miR-1302 hsa-miR-1302 0.0478509962967416 57 81 3 0.037037037037037 0.0526315789473684
MIRNA MIRNA:hsa-miR-4450 hsa-miR-4450 0.0478509962967416 65 71 3 0.0422535211267606 0.0461538461538462
MIRNA MIRNA:hsa-miR-7845-5p hsa-miR-7845-5p 0.0478509962967416 98 96 4 0.0416666666666667 0.0408163265306122
MIRNA MIRNA:hsa-miR-4648 hsa-miR-4648 0.0478509962967416 76 61 3 0.0491803278688525 0.0394736842105263
MIRNA MIRNA:hsa-miR-142-3p hsa-miR-142-3p 0.0478509962967416 386 25 4 0.16 0.0103626943005181
MIRNA MIRNA:hsa-miR-338-5p hsa-miR-338-5p 0.0484311063619295 104 45 3 0.0666666666666667 0.0288461538461538
MIRNA MIRNA:hsa-miR-149-5p hsa-miR-149-5p 0.0498725493093181 394 25 4 0.16 0.0101522842639594
REAC REAC:R-HSA-3371568 Attenuation phase 2.425758207728e-14 14 73 9 0.123287671232877 0.642857142857143
REAC REAC:R-HSA-3371556 Cellular response to heat stress 4.91917341617782e-14 87 87 15 0.172413793103448 0.172413793103448
REAC REAC:R-HSA-3371571 HSF1-dependent transactivation 4.91917341617782e-14 24 73 10 0.136986301369863 0.416666666666667
REAC REAC:R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 1.04466579536185e-12 57 17 8 0.470588235294118 0.140350877192982
REAC REAC:R-HSA-2262752 Cellular responses to stress 1.04466579536185e-12 546 19 14 0.736842105263158 0.0256410256410256
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 1.04466579536185e-12 560 19 14 0.736842105263158 0.025
REAC REAC:R-HSA-3371453 Regulation of HSF1-mediated heat shock response 9.50018862965404e-11 67 24 8 0.333333333333333 0.119402985074627
REAC REAC:R-HSA-9613829 Chaperone Mediated Autophagy 1.9638376846763e-08 22 19 5 0.263157894736842 0.227272727272727
REAC REAC:R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 2.02324707724125e-06 54 19 5 0.263157894736842 0.0925925925925926
REAC REAC:R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 1.93518887220924e-05 86 19 5 0.263157894736842 0.0581395348837209
REAC REAC:R-HSA-5687128 MAPK6/MAPK4 signaling 2.08978833634098e-05 89 19 5 0.263157894736842 0.0561797752808989
REAC REAC:R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 0.000134506619697607 17 19 3 0.157894736842105 0.176470588235294
REAC REAC:R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 0.000134506619697607 17 19 3 0.157894736842105 0.176470588235294
REAC REAC:R-HSA-9612973 Autophagy 0.000197494344252054 149 19 5 0.263157894736842 0.0335570469798658
REAC REAC:R-HSA-1643713 Signaling by EGFR in Cancer 0.000304433872154571 23 19 3 0.157894736842105 0.130434782608696
REAC REAC:R-HSA-6798695 Neutrophil degranulation 0.000309729310215868 474 13 6 0.461538461538462 0.0126582278481013
REAC REAC:R-HSA-9663891 Selective autophagy 0.000309729310215868 80 19 4 0.210526315789474 0.05
REAC REAC:R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 0.000309729310215868 79 19 4 0.210526315789474 0.0506329113924051
REAC REAC:R-HSA-3371511 HSF1 activation 0.000309729310215868 12 40 3 0.075 0.25
REAC REAC:R-HSA-8863795 Downregulation of ERBB2 signaling 0.000381348507292804 27 19 3 0.157894736842105 0.111111111111111
REAC REAC:R-HSA-9615710 Late endosomal microautophagy 0.000677224607987555 34 19 3 0.157894736842105 0.0882352941176471
REAC REAC:R-HSA-168249 Innate Immune System 0.000922110743164946 1073 19 9 0.473684210526316 0.00838769804287046
REAC REAC:R-HSA-9646399 Aggrephagy 0.00134971421808193 44 19 3 0.157894736842105 0.0681818181818182
REAC REAC:R-HSA-1227986 Signaling by ERBB2 0.00145254460231205 46 19 3 0.157894736842105 0.0652173913043478
REAC REAC:R-HSA-1632852 Macroautophagy 0.00161791621351007 134 19 4 0.210526315789474 0.0298507462686567
REAC REAC:R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 0.00188036720506948 55 19 3 0.157894736842105 0.0545454545454545
REAC REAC:R-HSA-5683057 MAPK family signaling cascades 0.00225399017748882 308 19 5 0.263157894736842 0.0162337662337662
REAC REAC:R-HSA-450294 MAP kinase activation 0.00237172229711593 63 19 3 0.157894736842105 0.0476190476190476
REAC REAC:R-HSA-8939211 ESR-mediated signaling 0.00251593617029196 181 18 4 0.222222222222222 0.0220994475138122
REAC REAC:R-HSA-448424 Interleukin-17 signaling 0.00265648279753974 71 19 3 0.157894736842105 0.0422535211267606
REAC REAC:R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 0.00267839430664041 76 19 3 0.157894736842105 0.0394736842105263
REAC REAC:R-HSA-9006931 Signaling by Nuclear Receptors 0.00267839430664041 255 40 6 0.15 0.0235294117647059
REAC REAC:R-HSA-69275 G2/M Transition 0.00267839430664041 196 19 4 0.210526315789474 0.0204081632653061
REAC REAC:R-HSA-453274 Mitotic G2-G2/M phases 0.00272530867326946 198 19 4 0.210526315789474 0.0202020202020202
REAC REAC:R-HSA-975871 MyD88 cascade initiated on plasma membrane 0.00287619496187413 84 19 3 0.157894736842105 0.0357142857142857
REAC REAC:R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 0.00287619496187413 84 19 3 0.157894736842105 0.0357142857142857
REAC REAC:R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 0.00287619496187413 84 19 3 0.157894736842105 0.0357142857142857
REAC REAC:R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 0.00294339940335106 85 19 3 0.157894736842105 0.0352941176470588
REAC REAC:R-HSA-2559580 Oxidative Stress Induced Senescence 0.00311529647129477 87 19 3 0.157894736842105 0.0344827586206897
REAC REAC:R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 0.00318482332371861 90 19 3 0.157894736842105 0.0333333333333333
REAC REAC:R-HSA-975155 MyD88 dependent cascade initiated on endosome 0.00322111346889377 91 19 3 0.157894736842105 0.032967032967033
REAC REAC:R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 0.00322111346889377 91 19 3 0.157894736842105 0.032967032967033
REAC REAC:R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 0.00329161234848237 92 19 3 0.157894736842105 0.0326086956521739
REAC REAC:R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 0.00340030600040643 94 19 3 0.157894736842105 0.0319148936170213
REAC REAC:R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 0.00340030600040643 94 19 3 0.157894736842105 0.0319148936170213
REAC REAC:R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 0.00341151189655918 96 19 3 0.157894736842105 0.03125
REAC REAC:R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 0.00341151189655918 95 19 3 0.157894736842105 0.0315789473684211
REAC REAC:R-HSA-166166 MyD88-independent TLR4 cascade 0.00341151189655918 96 19 3 0.157894736842105 0.03125
REAC REAC:R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 0.00345126437594059 97 19 3 0.157894736842105 0.0309278350515464
REAC REAC:R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 0.00345126437594059 97 19 3 0.157894736842105 0.0309278350515464
REAC REAC:R-HSA-2173788 Downregulation of TGF-beta receptor signaling 0.00372979782579466 24 81 3 0.037037037037037 0.125
REAC REAC:R-HSA-9018519 Estrogen-dependent gene expression 0.00382344305989783 112 40 4 0.1 0.0357142857142857
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.0042344212281446 446 19 5 0.263157894736842 0.0112107623318386
REAC REAC:R-HSA-1169408 ISG15 antiviral mechanism 0.00436511392739488 70 30 3 0.1 0.0428571428571429
REAC REAC:R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 0.0051813788283338 126 19 3 0.157894736842105 0.0238095238095238
REAC REAC:R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 0.0051813788283338 78 30 3 0.1 0.0384615384615385
REAC REAC:R-HSA-6807070 PTEN Regulation 0.00597652686251373 138 19 3 0.157894736842105 0.0217391304347826
REAC REAC:R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 0.00604779417225547 53 49 3 0.0612244897959184 0.0566037735849057
REAC REAC:R-HSA-8856828 Clathrin-mediated endocytosis 0.00651926658160263 144 19 3 0.157894736842105 0.0208333333333333
REAC REAC:R-HSA-422475 Axon guidance 0.00724381019062025 549 19 5 0.263157894736842 0.00910746812386157
REAC REAC:R-HSA-5663205 Infectious disease 0.00724381019062025 815 19 6 0.315789473684211 0.00736196319018405
REAC REAC:R-HSA-168898 Toll-like Receptor Cascades 0.00728623176488131 152 19 3 0.157894736842105 0.0197368421052632
REAC REAC:R-HSA-9609507 Protein localization 0.00788115230978926 158 19 3 0.157894736842105 0.0189873417721519
REAC REAC:R-HSA-2559583 Cellular Senescence 0.00798221311853407 159 19 3 0.157894736842105 0.0188679245283019
REAC REAC:R-HSA-9675108 Nervous system development 0.0083121855327364 574 19 5 0.263157894736842 0.00871080139372822
REAC REAC:R-HSA-1169091 Activation of NF-kappaB in B cells 0.00999915838756331 67 49 3 0.0612244897959184 0.0447761194029851
REAC REAC:R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 0.0102525031878529 182 19 3 0.157894736842105 0.0164835164835165
REAC REAC:R-HSA-8852135 Protein ubiquitination 0.0110803372925831 73 49 3 0.0612244897959184 0.0410958904109589
REAC REAC:R-HSA-157118 Signaling by NOTCH 0.0115081122370885 197 19 3 0.157894736842105 0.0152284263959391
REAC REAC:R-HSA-8953854 Metabolism of RNA 0.0116026517713427 658 35 7 0.2 0.0106382978723404
REAC REAC:R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 0.0128079859916367 80 49 3 0.0612244897959184 0.0375
REAC REAC:R-HSA-168256 Immune System 0.0146172705992256 2139 19 9 0.473684210526316 0.00420757363253857
REAC REAC:R-HSA-5653656 Vesicle-mediated transport 0.0147522989195296 717 19 5 0.263157894736842 0.00697350069735007
REAC REAC:R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 0.0169166464587784 485 10 3 0.3 0.00618556701030928
REAC REAC:R-HSA-1266738 Developmental Biology 0.0169166464587784 1069 19 6 0.315789473684211 0.00561272217025257
REAC REAC:R-HSA-1257604 PIP3 activates AKT signaling 0.0175016792271512 249 19 3 0.157894736842105 0.0120481927710843
REAC REAC:R-HSA-5607764 CLEC7A (Dectin-1) signaling 0.0182653974722582 97 49 3 0.0612244897959184 0.0309278350515464
REAC REAC:R-HSA-202424 Downstream TCR signaling 0.0187061738003809 98 49 3 0.0612244897959184 0.0306122448979592
REAC REAC:R-HSA-69278 Cell Cycle, Mitotic 0.0205861084847169 513 19 4 0.210526315789474 0.00779727095516569
REAC REAC:R-HSA-9006925 Intracellular signaling by second messengers 0.0238610830248931 289 19 3 0.157894736842105 0.0103806228373702
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 0.0241392165359153 842 19 5 0.263157894736842 0.00593824228028504
REAC REAC:R-HSA-913531 Interferon Signaling 0.0272653014278008 191 30 3 0.1 0.0157068062827225
REAC REAC:R-HSA-202403 TCR signaling 0.0293506484492528 120 49 3 0.0612244897959184 0.025
REAC REAC:R-HSA-3700989 Transcriptional Regulation by TP53 0.0390545060180202 360 19 3 0.157894736842105 0.00833333333333333
REAC REAC:R-HSA-1640170 Cell Cycle 0.0390545060180202 642 19 4 0.210526315789474 0.00623052959501558
REAC REAC:R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers 0.04112880133931 371 19 3 0.157894736842105 0.00808625336927224
REAC REAC:R-HSA-68886 M Phase 0.04112880133931 371 19 3 0.157894736842105 0.00808625336927224
REAC REAC:R-HSA-8951664 Neddylation 0.04112880133931 233 52 4 0.0769230769230769 0.0171673819742489
TF TF:M11656_1 Factor: HSF1; motif: RGAANRTTCYRGAAN; match class: 1 1.9536585941303e-22 219 16 14 0.875 0.0639269406392694
TF TF:M11655 Factor: HSF1; motif: NGAANGTTCKRGAAN 5.83863842441779e-20 1207 26 22 0.846153846153846 0.0182270091135046
TF TF:M09950_1 Factor: HSF1; motif: NRGAANNTTCYRGAA; match class: 1 9.94748282671374e-20 266 19 14 0.736842105263158 0.0526315789473684
TF TF:M11655_1 Factor: HSF1; motif: NGAANGTTCKRGAAN; match class: 1 7.71433349684418e-19 93 26 12 0.461538461538462 0.129032258064516
TF TF:M11654 Factor: HSF1; motif: RGAANRTTCYRGAAN 1.737653606093e-17 1353 26 21 0.807692307692308 0.0155210643015521
TF TF:M01023_1 Factor: HSF1; motif: NTTCTRGAAVNTTCTYM; match class: 1 2.32353204232128e-17 254 16 12 0.75 0.047244094488189
TF TF:M11654_1 Factor: HSF1; motif: RGAANRTTCYRGAAN; match class: 1 2.32353204232128e-17 113 14 10 0.714285714285714 0.0884955752212389
TF TF:M07100_1 Factor: HSF1; motif: NTTCTRGAANNTTCY; match class: 1 1.0953429143565e-16 514 26 16 0.615384615384615 0.0311284046692607
TF TF:M11656 Factor: HSF1; motif: RGAANRTTCYRGAAN 3.44277572230692e-16 2033 35 26 0.742857142857143 0.0127889818002951
TF TF:M11657 Factor: HSF1; motif: NGAANRTTCKAGAAN 2.66704151777386e-15 337 70 19 0.271428571428571 0.056379821958457
TF TF:M09950 Factor: HSF1; motif: NRGAANNTTCYRGAA 4.66407526546283e-15 2501 38 28 0.736842105263158 0.0111955217912835
TF TF:M11662 Factor: HSF2; motif: RGAANGTTCYRGAAN 2.68223495306384e-13 272 35 13 0.371428571428571 0.0477941176470588
TF TF:M11659 Factor: HSF4; motif: NGAANRTTCTAGAAN 5.46506688221512e-13 329 70 17 0.242857142857143 0.0516717325227964
TF TF:M07100 Factor: HSF1; motif: NTTCTRGAANNTTCY 5.46506688221512e-13 3350 38 29 0.763157894736842 0.00865671641791045
TF TF:M01023 Factor: HSF1; motif: NTTCTRGAAVNTTCTYM 5.46506688221512e-13 2721 38 27 0.710526315789474 0.00992282249173098
TF TF:M04008 Factor: HSF1; motif: TTCTAGAAYNTTC 2.06928226036725e-12 358 70 17 0.242857142857143 0.0474860335195531
TF TF:M11658 Factor: HSF4; motif: RGAANNTTCYRGAAN 3.3873404733538e-12 400 38 14 0.368421052631579 0.035
TF TF:M00147_1 Factor: HSF2; motif: NGAANNWTCK; match class: 1 1.46534792406654e-11 4404 26 24 0.923076923076923 0.00544959128065395
TF TF:M11662_1 Factor: HSF2; motif: RGAANGTTCYRGAAN; match class: 1 1.95184432582661e-11 12 14 5 0.357142857142857 0.416666666666667
TF TF:M01244 Factor: HSF2; motif: GAANRTTCTAGAA 7.66174241222494e-11 582 83 20 0.240963855421687 0.0343642611683849
TF TF:M11658_1 Factor: HSF4; motif: RGAANNTTCYRGAAN; match class: 1 1.66331276408793e-10 19 13 5 0.384615384615385 0.263157894736842
TF TF:M02017 Factor: HSF1; motif: GAANNTTCTRGNAN 1.94589475545166e-10 4046 39 29 0.743589743589744 0.00716757291151755
TF TF:M00641 Factor: HSF; motif: TTCCMGARGYTTC 1.87893519169952e-09 3599 26 21 0.807692307692308 0.00583495415393165
TF TF:M11657_1 Factor: HSF1; motif: NGAANRTTCKAGAAN; match class: 1 1.9131435435549e-09 15 26 5 0.192307692307692 0.333333333333333
TF TF:M07459_1 Factor: HSF1; motif: GAANNTTCTNGN; match class: 1 2.28398639766697e-09 413 38 12 0.315789473684211 0.0290556900726392
TF TF:M00147 Factor: HSF2; motif: NGAANNWTCK 2.28398639766697e-09 5830 27 25 0.925925925925926 0.00428816466552316
TF TF:M11659_1 Factor: HSF4; motif: NGAANRTTCTAGAAN; match class: 1 2.35534692637027e-08 14 13 4 0.307692307692308 0.285714285714286
TF TF:M04008_1 Factor: HSF1; motif: TTCTAGAAYNTTC; match class: 1 2.35534692637027e-08 14 13 4 0.307692307692308 0.285714285714286
TF TF:M07259_1 Factor: HSF1; motif: TCYAGAANNTTC; match class: 1 5.87699268171394e-08 732 30 12 0.4 0.0163934426229508
TF TF:M04010 Factor: HSF4; motif: TTCTAGAANNTTC 1.15299372134827e-07 185 21 7 0.333333333333333 0.0378378378378378
TF TF:M01244_1 Factor: HSF2; motif: GAANRTTCTAGAA; match class: 1 2.67770199323995e-07 25 13 4 0.307692307692308 0.16
TF TF:M02017_1 Factor: HSF1; motif: GAANNTTCTRGNAN; match class: 1 6.05478849996573e-07 543 16 8 0.5 0.0147329650092081
TF TF:M07358 Factor: HSF2; motif: NGGAATNTTCTNGNRN 1.30927097123153e-06 576 30 10 0.333333333333333 0.0173611111111111
TF TF:M07259 Factor: HSF1; motif: TCYAGAANNTTC 3.56077478991633e-06 4742 39 26 0.666666666666667 0.00548291859974694
TF TF:M07459 Factor: HSF1; motif: GAANNTTCTNGN 4.92222102227297e-06 3422 25 17 0.68 0.00496785505552309
TF TF:M02102 Factor: NRF-1; motif: YGCGCMTGCGC 5.12951363529627e-05 2020 61 21 0.344262295081967 0.0103960396039604
TF TF:M08457_1 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY; match class: 1 8.99339947889643e-05 5591 73 41 0.561643835616438 0.00733321409407977
TF TF:M07250_1 Factor: E2F-1; motif: NNNSSCGCSAANN; match class: 1 0.000115865573915389 5515 33 23 0.696969696969697 0.00417044424297371
TF TF:M04001 Factor: GCM1; motif: NATGCGGGTAC 0.000179889003237298 388 11 5 0.454545454545455 0.0128865979381443
TF TF:M04010_1 Factor: HSF4; motif: TTCTAGAANNTTC; match class: 1 0.000302402219270592 6 94 3 0.0319148936170213 0.5
TF TF:M04694 Factor: NRF-1; motif: CNCTGCGCATGCGC 0.0004076347301078 1548 61 17 0.278688524590164 0.0109819121447028
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.000506659450011161 10253 73 57 0.780821917808219 0.00555934848337072
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.000572621589061309 7045 37 27 0.72972972972973 0.00383250532292406
TF TF:M04950_1 Factor: Egr-1; motif: NGCGTGCGY; match class: 1 0.000664457025196565 5551 42 26 0.619047619047619 0.00468384074941452
TF TF:M11660 Factor: HSF2; motif: RGAAYRTTCYRGAAN 0.000686832903982928 66 35 4 0.114285714285714 0.0606060606060606
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.000686832903982928 10765 20 20 1 0.0018578727357176
TF TF:M10018 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS 0.000689894481189297 1816 61 18 0.295081967213115 0.00991189427312775
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.000699992059449738 11423 22 22 1 0.00192593889521142
TF TF:M09732 Factor: RFX3; motif: NYNCCMTGGCAACM 0.000708708418774287 5207 9 9 1 0.00172844248127521
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.000814748846316825 6033 20 16 0.8 0.00265208022542682
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.000869341280277067 8322 37 29 0.783783783783784 0.00348473924537371
TF TF:M00736_1 Factor: E2F-1:DP-1; motif: TTTCSCGC; match class: 1 0.000891929126585839 4639 66 32 0.484848484848485 0.00689803837033843
TF TF:M08377_1 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1 0.000894692574716057 5051 27 18 0.666666666666667 0.0035636507622253
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.00110067165982521 5332 20 15 0.75 0.00281320330082521
TF TF:M00641_1 Factor: HSF; motif: TTCCMGARGYTTC; match class: 1 0.00123675747286646 387 73 9 0.123287671232877 0.0232558139534884
TF TF:M08213 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN 0.00123675747286646 6273 20 16 0.8 0.00255061374143153
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.00137507407456238 11232 73 59 0.808219178082192 0.005252849002849
TF TF:M00144_1 Factor: Pax-5; motif: RRMSWGANWYCTNRAGCGKRACSRYNSM; match class: 1 0.0014155800970769 7128 22 18 0.818181818181818 0.00252525252525253
TF TF:M09632 Factor: Kaiso; motif: GNTCTCGCGAGRNNNNGGN 0.00149139844738032 3001 42 18 0.428571428571429 0.00599800066644452
TF TF:M05386 Factor: KLF17; motif: NGGGCGG 0.00149938396100406 7900 12 12 1 0.00151898734177215
TF TF:M08884 Factor: GCM; motif: NNNNATGMGGGN 0.00149938396100406 1185 11 6 0.545454545454545 0.00506329113924051
TF TF:M05499 Factor: LKLF; motif: NGGGCGG 0.00149938396100406 7900 12 12 1 0.00151898734177215
TF TF:M09641 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN 0.00167852799436736 3222 40 18 0.45 0.00558659217877095
TF TF:M11880_1 Factor: pax-6; motif: NYACGCWTSANYGMNCN; match class: 1 0.00189966879117437 7046 41 28 0.682926829268293 0.00397388589270508
TF TF:M11400 Factor: Fli-1; motif: NACCGGAARTN 0.00196058535507332 9946 20 19 0.95 0.00191031570480595
TF TF:M12000_1 Factor: AML3; motif: NNAACCGCAAWAACCGCAAN; match class: 1 0.00198773257388474 1586 13 7 0.538461538461538 0.00441361916771753
TF TF:M09832 Factor: RFX1; motif: NGTTGCCATGG 0.00204943783696839 2370 5 5 1 0.00210970464135021
TF TF:M04002 Factor: GCMb; motif: NATGCGGGTN 0.00209926967982926 1282 11 6 0.545454545454545 0.0046801872074883
TF TF:M11596 Factor: GCMb; motif: ATGCGGGYN 0.00219800748946165 737 11 5 0.454545454545455 0.0067842605156038
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.00227145168890538 4024 40 20 0.5 0.00497017892644135
TF TF:M00976_1 Factor: AhR,; motif: NRCGTGNGN; match class: 1 0.00240736380850332 1011 41 10 0.24390243902439 0.00989119683481701
TF TF:M09732_1 Factor: RFX3; motif: NYNCCMTGGCAACM; match class: 1 0.0024158712017185 982 14 6 0.428571428571429 0.00610997963340122
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.00245753251709449 2702 32 14 0.4375 0.00518134715025907
TF TF:M00737_1 Factor: E2F-1:DP-2; motif: TTTSSCGC; match class: 1 0.00267018267638713 2933 45 18 0.4 0.00613706102966246
TF TF:M00634 Factor: GCM; motif: CNNRCCCGCATD 0.00294485360642517 2152 11 7 0.636363636363636 0.00325278810408922
TF TF:M07052 Factor: NRF-1; motif: GCGCMTGCGCN 0.00308782550606014 2130 40 14 0.35 0.00657276995305164
TF TF:M10635_1 Factor: Nkx2-3; motif: GNCGTTRAG; match class: 1 0.00316947357555866 703 3 3 1 0.0042674253200569
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.00322736698529888 8219 18 16 0.888888888888889 0.00194670884535832
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.00326912772527556 12550 22 22 1 0.00175298804780877
TF TF:M00955_1 Factor: GR; motif: NNNNNNNGKACNNNNTGTTCTNNNNNN; match class: 1 0.0034575830528471 754 12 5 0.416666666666667 0.00663129973474801
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00353709112056724 11053 17 17 1 0.00153804396996291
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.00374951022567406 10262 27 24 0.888888888888889 0.00233872539465991
TF TF:M04106_1 Factor: RUNX2; motif: NRACCGCAAACCGCAN; match class: 1 0.00397160770777109 8372 66 44 0.666666666666667 0.00525561395126613
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.00397754365630042 4607 32 18 0.5625 0.00390709789450836
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.00403596652062201 10512 20 19 0.95 0.00180745814307458
TF TF:M03574 Factor: GCMa; motif: CCCGCAT 0.00471982149886368 2362 11 7 0.636363636363636 0.00296359017781541
TF TF:M03824 Factor: GCMb; motif: RCCCKCAT 0.0047826072463916 1550 11 6 0.545454545454545 0.00387096774193548
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.0049311806979917 8318 38 28 0.736842105263158 0.00336619379658572
TF TF:M09608_1 Factor: Erg; motif: NNACCGGAARTSN; match class: 1 0.0049311806979917 2389 52 17 0.326923076923077 0.00711594809543742
TF TF:M00113 Factor: CREB; motif: NNGNTGACGTNN 0.0049311806979917 4801 24 15 0.625 0.00312434909393876
TF TF:M00177 Factor: CREB; motif: NSTGACGTAANN 0.0049311806979917 5221 96 43 0.447916666666667 0.00823597012066654
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.00494237621362086 8273 33 25 0.757575757575758 0.0030218783996132
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.00506512760171571 5745 32 20 0.625 0.00348128807658834
TF TF:M11218_1 Factor: CREB1; motif: NRTGAYGCGTN; match class: 1 0.00513526940686735 2438 11 7 0.636363636363636 0.00287120590648072
TF TF:M02067 Factor: ER71; motif: ACCGGAARYN 0.00516698523421812 5930 27 18 0.666666666666667 0.003035413153457
TF TF:M07313 Factor: ATF-3; motif: SNTGACGYNATN 0.00537041048936771 2894 22 11 0.5 0.00380096751900484
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.00544149538784507 9162 71 49 0.690140845070423 0.0053481772538747
TF TF:M08423 Factor: TEF-3:ER81; motif: ACCGGAAATRCC 0.00556360253096104 3845 32 16 0.5 0.00416124837451235
TF TF:M00737 Factor: E2F-1:DP-2; motif: TTTSSCGC 0.00584583513121726 8771 42 31 0.738095238095238 0.00353437464371223
TF TF:M05439_1 Factor: RREB-1; motif: GGGWCSA; match class: 1 0.00585393732759595 3200 27 13 0.481481481481481 0.0040625
TF TF:M11430 Factor: PEA3; motif: NACCGGAAGTN 0.00598706708321633 10865 20 19 0.95 0.00174873446847676
TF TF:M04710_1 Factor: CHD2; motif: TCTCGCGAG; match class: 1 0.00617342827549367 11477 42 36 0.857142857142857 0.00313670819900671
TF TF:M05327 Factor: WT1; motif: NGCGGGGGGGTSMMCYN 0.00617342827549367 5509 18 13 0.722222222222222 0.00235977491377745
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.00617660299761915 4056 40 19 0.475 0.00468441814595661
TF TF:M01104 Factor: MOVO-B; motif: GNGGGGG 0.00617660299761915 10261 22 20 0.909090909090909 0.00194912776532502
TF TF:M02090_1 Factor: E2F-4; motif: GCGGGAAANA; match class: 1 0.00617660299761915 6378 45 27 0.6 0.00423330197554092
TF TF:M03976_1 Factor: ERG; motif: ACCGGAWATCCGGT; match class: 1 0.00620071577636856 7781 21 17 0.80952380952381 0.00218480915049479
TF TF:M08877 Factor: EGR3; motif: NCMCRCCCACTNMN 0.00620071577636856 6099 15 12 0.8 0.00196753566158387
TF TF:M00146 Factor: HSF1; motif: AGAANRTTCN 0.00623115551080974 2678 24 11 0.458333333333333 0.0041075429424944
TF TF:M03821 Factor: ER-beta; motif: ANNSTGACCYRGNN 0.00634607898758118 6456 20 15 0.75 0.00232342007434944
TF TF:M00986 Factor: Churchill; motif: CGGGNN 0.00663407617033862 14197 27 27 1 0.00190181024160034
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00668662318571892 13184 22 22 1 0.00166868932038835
TF TF:M11448_1 Factor: Elf-1; motif: NANGCGGAAGTN; match class: 1 0.00706749759850245 2324 66 19 0.287878787878788 0.00817555938037866
TF TF:M00243 Factor: Egr-1; motif: WTGCGTGGGCGK 0.00706749759850245 5356 96 43 0.447916666666667 0.00802837938760269
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 0.00710363234172566 13929 73 65 0.89041095890411 0.00466652308134109
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.00725195799691736 8056 38 27 0.710526315789474 0.00335153922542205
TF TF:M01814 Factor: AML2; motif: CCRCACCA 0.00733599856752909 2741 17 9 0.529411764705882 0.00328347318496899
TF TF:M10638 Factor: Nkx2-3; motif: NNCGTTRWS 0.00749631832188067 10804 27 24 0.888888888888889 0.00222139948167345
TF TF:M05444_1 Factor: CPBP; motif: NGGGCGG; match class: 1 0.0075442516599954 3313 76 26 0.342105263157895 0.00784787201931784
TF TF:M05361_1 Factor: Sp6; motif: WGGGCGG; match class: 1 0.0075442516599954 3313 76 26 0.342105263157895 0.00784787201931784
TF TF:M05332_1 Factor: Sp2; motif: WGGGCGG; match class: 1 0.0075442516599954 3313 76 26 0.342105263157895 0.00784787201931784
TF TF:M01217_1 Factor: NUR77; motif: NTGACCTTBN; match class: 1 0.00765460732504088 58 37 3 0.0810810810810811 0.0517241379310345
TF TF:M09826 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC 0.00789902630718245 11467 21 20 0.952380952380952 0.00174413534490276
TF TF:M07084 Factor: E2F-4; motif: NGGCGGGAARN 0.00798261972028207 10834 71 54 0.76056338028169 0.00498430865792874
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.00834254260190286 6892 37 24 0.648648648648649 0.00348229831688915
TF TF:M04823_1 Factor: E2F-4; motif: NNTTCCCGCCNN; match class: 1 0.00834254260190286 7850 64 40 0.625 0.00509554140127389
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.00851053461676504 8690 38 28 0.736842105263158 0.00322209436133487
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.00851053461676504 4592 40 20 0.5 0.00435540069686411
TF TF:M11883 Factor: pax-6; motif: NYACGCNTSRNYGCNYN 0.0088872806634964 13445 22 22 1 0.00163629602082559
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.00892683072516707 8743 20 17 0.85 0.00194441267299554
TF TF:M12227_1 Factor: ZIC4; motif: NNCCNCCCRYNGYGN; match class: 1 0.00921949032246457 5898 64 33 0.515625 0.00559511698880977
TF TF:M11022_1 Factor: IRX2a; motif: ACRYGNNNNACRYGT; match class: 1 0.00926952764472006 6246 73 38 0.520547945205479 0.00608389369196286
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.00961955895255662 12729 19 19 1 0.00149265456830859
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.00992395190617684 10116 27 23 0.851851851851852 0.00227362593910637
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.00995846136895827 10357 21 19 0.904761904761905 0.00183450806218017
TF TF:M06292 Factor: ZNF766; motif: NCGTGAAGGAAA 0.0100723022538062 146 42 4 0.0952380952380952 0.0273972602739726
TF TF:M11696 Factor: MEF-2B1; motif: CCNWATWWRG 0.0102687303395471 2268 39 13 0.333333333333333 0.00573192239858906
TF TF:M11271 Factor: JunD; motif: NRTGACGCAYN 0.0102687303395471 7009 35 23 0.657142857142857 0.00328149522043087
TF TF:M11597 Factor: GCMb; motif: ATGCGGGTN 0.0103528707045544 1192 11 5 0.454545454545455 0.00419463087248322
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.0104798964631122 11728 21 20 0.952380952380952 0.00170532060027285
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.0109311408716807 4963 33 18 0.545454545454545 0.00362683860568205
TF TF:M03989 Factor: FLI1; motif: ACCGGAAATCCGGT 0.0109311408716807 10442 21 19 0.904761904761905 0.00181957479410075
TF TF:M01820_1 Factor: CREM; motif: TGACGTCASYN; match class: 1 0.010954476265086 1879 20 8 0.4 0.00425758382118148
TF TF:M11401_1 Factor: Fli-1; motif: NACCGGATATCCGGTN; match class: 1 0.0113174127368297 11801 21 20 0.952380952380952 0.00169477162952292
TF TF:M01861_1 Factor: ATF-1; motif: TNACGTCAN; match class: 1 0.0113174127368297 1896 20 8 0.4 0.00421940928270042
TF TF:M09607 Factor: SAP-1; motif: ACCGGAAGTNN 0.0113174127368297 4727 40 20 0.5 0.00423101332769198
TF TF:M05432 Factor: ZSCAN18; motif: TRRCGRCGNMCC 0.011413450494293 4117 11 8 0.727272727272727 0.00194316249696381
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.011413450494293 10002 38 30 0.789473684210526 0.002999400119976
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.0115103431095183 10585 41 33 0.804878048780488 0.0031176192725555
TF TF:M00803_1 Factor: E2F; motif: GGCGSG; match class: 1 0.0115103431095183 10230 42 33 0.785714285714286 0.0032258064516129
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.0123159729895395 9474 38 29 0.763157894736842 0.0030610090774752
TF TF:M01165_1 Factor: Elk-1; motif: RACCGGAAGTR; match class: 1 0.0127521801145309 2185 52 15 0.288461538461538 0.0068649885583524
TF TF:M03990 Factor: GABPA; motif: ACCGGAAGTN 0.0127762416896127 5258 37 20 0.540540540540541 0.00380372765310004
TF TF:M11881_1 Factor: pax-6; motif: NYACGCNTSANYGCNYN; match class: 1 0.0128041363475817 7158 41 26 0.634146341463415 0.00363229952500699
TF TF:M11491_1 Factor: LBP9; motif: ACYRGTTNNAACYRGT; match class: 1 0.0131756874304343 4149 55 23 0.418181818181818 0.00554350445890576
TF TF:M11401 Factor: Fli-1; motif: NACCGGATATCCGGTN 0.0132075212519124 11952 21 20 0.952380952380952 0.00167336010709505
TF TF:M01770_1 Factor: XBP-1; motif: WNNGMCACGTC; match class: 1 0.0141302891284224 4554 76 31 0.407894736842105 0.00680720245937637
TF TF:M11397 Factor: Erg; motif: NACCGGATATCCGGTN 0.0141302891284224 12005 21 20 0.952380952380952 0.00166597251145356
TF TF:M08800 Factor: ARNT; motif: YRCGTGNN 0.0141302891284224 914 15 5 0.333333333333333 0.00547045951859956
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.0144213360897503 4639 33 17 0.515151515151515 0.00366458288424229
TF TF:M08205_1 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1 0.0146416164819943 10438 73 53 0.726027397260274 0.00507760107300249
TF TF:M07380_1 Factor: E2F-4; motif: NTTTCSCGCC; match class: 1 0.014742629400433 7965 77 46 0.597402597402597 0.00577526679221595
TF TF:M07395 Factor: Sp1; motif: NGGGGCGGGGN 0.0151394420425434 10640 72 53 0.736111111111111 0.0049812030075188
TF TF:M08344 Factor: HOXB2:ER81; motif: ACCGGAAATGA 0.0151610493305349 101 30 3 0.1 0.0297029702970297
TF TF:M08487 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG 0.0152218636485057 13942 22 22 1 0.00157796585855688
TF TF:M07206_1 Factor: E2F-1; motif: NGGGCGGGARV; match class: 1 0.0156241811340454 10849 71 53 0.746478873239437 0.00488524287952807
TF TF:M04863_1 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG; match class: 1 0.0157514406676014 8573 21 17 0.80952380952381 0.00198296978887204
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.0157514406676014 9423 37 28 0.756756756756757 0.00297145282818635
TF TF:M08759 Factor: c-Ets-2; motif: NCCGGAAGTG 0.0157514406676014 8319 37 26 0.702702702702703 0.00312537564611131
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.0157514406676014 12401 22 21 0.954545454545455 0.00169341182162729
TF TF:M08905_1 Factor: TIEG1; motif: GGSGGKGNNN; match class: 1 0.0158794412294846 1017 4 3 0.75 0.00294985250737463
TF TF:M11733 Factor: PXR; motif: NYGAACTSNNTGAACTC 0.0158794412294846 2983 4 4 1 0.00134093194770365
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.0158794412294846 6749 33 21 0.636363636363636 0.0031115720847533
TF TF:M11595 Factor: GCMa; motif: RTGCGGGTN 0.0163224915672275 12117 42 36 0.857142857142857 0.00297103243377074
TF TF:M11962_1 Factor: rfx1; motif: NGTTRCCATGGYAACN; match class: 1 0.0163224915672275 3181 14 8 0.571428571428571 0.00251493241119145
TF TF:M11280 Factor: FOSB; motif: NATGAYGTCATN 0.0164493691790448 436 8 3 0.375 0.00688073394495413
TF TF:M07387 Factor: LRF; motif: NGKGGGTSNCN 0.016760929790314 5232 8 7 0.875 0.00133792048929664
TF TF:M03981 Factor: ETV3; motif: ACCGGAAGTN 0.0170850192946536 2327 36 12 0.333333333333333 0.00515685431886549
TF TF:M11961_1 Factor: rfx1; motif: NGTTRCCATGGYAACN; match class: 1 0.0173150018921818 4172 14 9 0.642857142857143 0.00215723873441994
TF TF:M08313_1 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR; match class: 1 0.0176622644499059 9721 24 20 0.833333333333333 0.0020574015019031
TF TF:M11962 Factor: rfx1; motif: NGTTRCCATGGYAACN 0.0177328788586529 3235 14 8 0.571428571428571 0.00247295208655332
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.017755166889274 14096 22 22 1 0.00156072644721907
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.0177673642090831 14106 22 22 1 0.00155962001984971
TF TF:M04710 Factor: CHD2; motif: TCTCGCGAG 0.0177673642090831 14109 22 22 1 0.00155928839747679
TF TF:M12140 Factor: Egr-1; motif: NNCRCCCMCGCNN 0.0177673642090831 5360 16 11 0.6875 0.00205223880597015
TF TF:M01972 Factor: EGR-1; motif: TGCGTGGGCGK 0.0177673642090831 5360 16 11 0.6875 0.00205223880597015
TF TF:M11228_1 Factor: ATF-6; motif: GRTGACGTCAYC; match class: 1 0.0179150152126803 2102 20 8 0.4 0.00380589914367269
TF TF:M05361 Factor: Sp6; motif: WGGGCGG 0.018239344389056 8578 77 48 0.623376623376623 0.00559570995570063
TF TF:M05444 Factor: CPBP; motif: NGGGCGG 0.018239344389056 8578 77 48 0.623376623376623 0.00559570995570063
TF TF:M05332 Factor: Sp2; motif: WGGGCGG 0.018239344389056 8578 77 48 0.623376623376623 0.00559570995570063
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.0182880494450897 11275 22 20 0.909090909090909 0.00177383592017738
TF TF:M12158_1 Factor: KLF15; motif: NCCMCGCCCMCN; match class: 1 0.0182880494450897 6004 21 14 0.666666666666667 0.00233177881412392
TF TF:M10024_1 Factor: p63; motif: NRCAWGYCCAGRCWTGYNN; match class: 1 0.0183086329385185 326 11 3 0.272727272727273 0.00920245398773006
TF TF:M08878_1 Factor: EGR; motif: CGCCCCCGCNN; match class: 1 0.0183645345162436 3224 24 11 0.458333333333333 0.00341191066997519
TF TF:M11228 Factor: ATF-6; motif: GRTGACGTCAYC 0.0183645345162436 2123 20 8 0.4 0.00376825247291569
TF TF:M11961 Factor: rfx1; motif: NGTTRCCATGGYAACN 0.0183645345162436 4244 14 9 0.642857142857143 0.00212064090480679
TF TF:M08878 Factor: EGR; motif: CGCCCCCGCNN 0.0183859758532203 7483 18 14 0.777777777777778 0.00187090739008419
TF TF:M07296 Factor: MAF; motif: GCTGAGTCAN 0.0187152369673909 5670 22 14 0.636363636363636 0.00246913580246914
TF TF:M10635 Factor: Nkx2-3; motif: GNCGTTRAG 0.0189555305841301 4594 11 8 0.727272727272727 0.00174140182847192
TF TF:M06948 Factor: Sp2; motif: TGGGCGCGCCCA 0.0190677062744731 8864 77 49 0.636363636363636 0.00552797833935018
TF TF:M11179_1 Factor: ASH-2; motif: ACACGACGCN; match class: 1 0.0195097243334452 165 49 4 0.0816326530612245 0.0242424242424242
TF TF:M06130 Factor: ZNF254; motif: KGGTWCKAAGGM 0.0195097243334452 53 66 3 0.0454545454545455 0.0566037735849057
TF TF:M02072 Factor: Pet-1; motif: ACCGGAWRTN 0.0196343302871744 2395 36 12 0.333333333333333 0.00501043841336117
TF TF:M08231 Factor: Elk-1:T-bet; motif: TCACACCGGAAGNN 0.0200938607633888 6635 32 20 0.625 0.00301431801055011
TF TF:M00244 Factor: NGFI-C; motif: WTGCGTGGGYGG 0.0200938607633888 6184 25 16 0.64 0.00258732212160414
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.0203995838661819 7600 27 19 0.703703703703704 0.0025
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.0203995838661819 5133 29 16 0.551724137931034 0.00311708552503409
TF TF:M10849_1 Factor: Cdx-2; motif: NRTCGTAANNNN; match class: 1 0.0204683905133573 4497 63 26 0.412698412698413 0.00578163219924394
TF TF:M09887 Factor: CREB1; motif: NRRTGACGTMA 0.0204683905133573 5419 23 14 0.608695652173913 0.00258350249123454
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.0204683905133573 10233 72 51 0.708333333333333 0.00498387569627675
TF TF:M00280 Factor: RFX1; motif: NNGTNRCNWRGYAACNN 0.0209495825465459 6402 42 24 0.571428571428571 0.00374882849109653
TF TF:M04106 Factor: RUNX2; motif: NRACCGCAAACCGCAN 0.0209495825465459 13833 39 36 0.923076923076923 0.00260247234873129
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.0210598920155206 10939 12 12 1 0.00109699241246915
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.0210686661675459 10430 71 51 0.71830985915493 0.00488974113135187
TF TF:M10999 Factor: LIM-1; motif: NNCGTTAN 0.0211168938367383 5894 55 28 0.509090909090909 0.00475059382422803
TF TF:M11304 Factor: batf3; motif: NRTGAYGTCAYN 0.0211168938367383 763 12 4 0.333333333333333 0.00524246395806029
TF TF:M04027 Factor: MEIS1; motif: NTGACAN 0.021269734981839 3387 4 4 1 0.00118098612341305
TF TF:M03558_1 Factor: P73; motif: GNNNRRRCNTGCMNNTSASN; match class: 1 0.021623474441013 822 19 5 0.263157894736842 0.00608272506082725
TF TF:M11222 Factor: CREB1; motif: NRTGAYGTCAYN 0.0220846826673418 3688 19 10 0.526315789473684 0.0027114967462039
TF TF:M01241_1 Factor: BEN; motif: CWGCGAYA; match class: 1 0.0221930747060232 2097 21 8 0.380952380952381 0.00381497377205532
TF TF:M03966 Factor: ELF1; motif: AACCCGGAAGTR 0.0223865024033582 6610 20 14 0.7 0.00211800302571861
TF TF:M11831 Factor: LRH-1; motif: TCAAGGTCRTGACCTTGA 0.0223890470975139 3558 40 16 0.4 0.00449690837549185
TF TF:M07250 Factor: E2F-1; motif: NNNSSCGCSAANN 0.0223890470975139 10703 36 29 0.805555555555556 0.00270952069513221
TF TF:M10632_1 Factor: Nkx2-8; motif: STCGTTGAN; match class: 1 0.0223890470975139 831 73 10 0.136986301369863 0.0120336943441637
TF TF:M07204 Factor: AR; motif: ARGAACANNNTGTNC 0.0224436387611289 4906 13 9 0.692307692307692 0.00183448838157358
TF TF:M08281 Factor: Fli-1:C/EBPbeta; motif: RNCGGAWRTTGCGCAAY 0.0228027864538432 7571 76 43 0.565789473684211 0.00567956676793026
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.0229668873087859 15260 27 27 1 0.00176933158584535
TF TF:M00246 Factor: Egr-2; motif: NTGCGTRGGCGK 0.0233951802820022 6212 13 10 0.769230769230769 0.00160978750804894
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.0236725363155124 14873 73 66 0.904109589041096 0.00443757143817656
TF TF:M11218 Factor: CREB1; motif: NRTGAYGCGTN 0.0243925934197865 8461 17 14 0.823529411764706 0.0016546507505023
TF TF:M09893 Factor: E2F-3; motif: NNGGCGGGAAA 0.0247643689690081 6065 77 37 0.480519480519481 0.00610057708161583
TF TF:M12187 Factor: KLF17; motif: NMCCACNCWCCCNTN 0.0252579633787782 2886 20 9 0.45 0.00311850311850312
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.0252579633787782 14473 22 22 1 0.00152007185794238
TF TF:M04109_1 Factor: RUNX3; motif: NRACCGCAAACCGCAN; match class: 1 0.0254258073830874 3878 55 21 0.381818181818182 0.00541516245487365
TF TF:M12052 Factor: OSR2; motif: NGCTACYGNN 0.0254258073830874 1626 27 8 0.296296296296296 0.00492004920049201
TF TF:M12085 Factor: ZNF501; motif: NNNCSACGCGAACAC 0.0254258073830874 8467 45 30 0.666666666666667 0.00354316759182709
TF TF:M05837 Factor: ZFP2; motif: NCCWCGGGRATA 0.0259483364367879 188 22 3 0.136363636363636 0.0159574468085106
TF TF:M03803_1 Factor: Sox-17; motif: TTGTYY; match class: 1 0.0262441937902832 9532 13 12 0.923076923076923 0.00125891733109526
TF TF:M01778 Factor: PLAG1; motif: GRGGCNNHNNNRRGGG 0.0269114721343258 2743 61 18 0.295081967213115 0.00656215822092599
TF TF:M09896 Factor: E2F-7; motif: GRGGCGGGAANNN 0.0276222605616162 9927 73 50 0.684931506849315 0.00503676840938854
TF TF:M11183 Factor: MyoD; motif: CGNCAGSTGTTN 0.0276222605616162 3348 9 6 0.666666666666667 0.0017921146953405
TF TF:M11425 Factor: PEA3; motif: NACCGGAAGTN 0.0276222605616162 7428 38 24 0.631578947368421 0.00323101777059774
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.027728386866319 4201 55 22 0.4 0.00523684836943585
TF TF:M00981_1 Factor: CREB,; motif: NTGACGTNA; match class: 1 0.0277637322369901 2904 24 10 0.416666666666667 0.0034435261707989
TF TF:M11508 Factor: CDP; motif: NNATYGATYN 0.0278725771044724 3768 6 5 0.833333333333333 0.00132696390658174
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.0283805416205394 14593 22 22 1 0.00150757212362091
TF TF:M05386_1 Factor: KLF17; motif: NGGGCGG; match class: 1 0.0291646055522987 2513 15 7 0.466666666666667 0.00278551532033426
TF TF:M05499_1 Factor: LKLF; motif: NGGGCGG; match class: 1 0.0291646055522987 2513 15 7 0.466666666666667 0.00278551532033426
TF TF:M11022 Factor: IRX2a; motif: ACRYGNNNNACRYGT 0.0295331644934183 9487 76 50 0.657894736842105 0.00527036997997259
TF TF:M09867 Factor: ATF-2; motif: RRTGANGTCAY 0.0301319879390289 4328 23 12 0.521739130434783 0.00277264325323475
TF TF:M04486 Factor: RARG; motif: RAGGTCANNNRAGGTCA 0.0305175451679959 1711 11 5 0.454545454545455 0.00292226767971946
TF TF:M02054 Factor: ELF2; motif: CCCGGAARYN 0.0305746409223303 3066 27 11 0.407407407407407 0.00358773646444879
TF TF:M11491 Factor: LBP9; motif: ACYRGTTNNAACYRGT 0.0311456708820474 5146 55 25 0.454545454545455 0.00485814224640497
TF TF:M11298 Factor: jdp2; motif: NRTGACGTCAYN 0.0312017073366016 1597 35 9 0.257142857142857 0.00563556668753914
TF TF:M11533 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN 0.0312036738008667 13105 22 21 0.954545454545455 0.00160244181610072
TF TF:M11399_1 Factor: Fli-1; motif: NACCGGAWWTCCGGTY; match class: 1 0.0312466583229966 11513 21 19 0.904761904761905 0.0016503083470859
TF TF:M11486 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.0317467938028199 3658 37 15 0.405405405405405 0.00410060142154183
TF TF:M04744_1 Factor: ATF-3; motif: GGCGCSSNSNGRTSACGTSA; match class: 1 0.031799162991546 4889 21 12 0.571428571428571 0.0024544896706893
TF TF:M08779 Factor: PXR; motif: AGTTCANNSAGTTC 0.031799162991546 3913 4 4 1 0.00102223358037312
TF TF:M11883_1 Factor: pax-6; motif: NYACGCNTSRNYGCNYN; match class: 1 0.0323054256338921 7768 41 26 0.634146341463415 0.0033470648815654
TF TF:M12086 Factor: ZNF501; motif: NNGCGACGCGAACAN 0.0325315052775876 1830 63 14 0.222222222222222 0.00765027322404372
TF TF:M00938_1 Factor: E2F-1; motif: TTGGCGCGRAANNGNM; match class: 1 0.0325315052775876 2573 61 17 0.278688524590164 0.00660707345511077
TF TF:M08225_1 Factor: Elk-1:Pax-5; motif: ACCGGAACYACGCWTSANYG; match class: 1 0.0325315052775876 7993 78 45 0.576923076923077 0.00562992618541224
TF TF:M00929 Factor: MyoD; motif: CNGNRNCAGGTGNNGNAN 0.0325474020570008 1488 4 3 0.75 0.00201612903225806
TF TF:M04626 Factor: Prop-1; motif: WNCTWATT 0.0325474020570008 764 23 5 0.217391304347826 0.00654450261780105
TF TF:M00736 Factor: E2F-1:DP-1; motif: TTTCSCGC 0.0325965540631761 10390 66 47 0.712121212121212 0.00452358036573629
TF TF:M11221 Factor: CREB1; motif: RTGACGYGTCAN 0.032810459324725 9677 22 18 0.818181818181818 0.00186008060349282
TF TF:M10432 Factor: MAZ; motif: GGGMGGGGS 0.0337873681498189 9259 18 15 0.833333333333333 0.00162004536127012
TF TF:M03982 Factor: ETV4; motif: ACCGGAAGTN 0.0339014949684818 6826 37 22 0.594594594594595 0.00322297099326106
TF TF:M03949 Factor: TFCP2; motif: ACCGGTTNAAACYGGT 0.0339014949684818 502 10 3 0.3 0.00597609561752988
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.0341152981762127 3233 30 12 0.4 0.0037117228580266
TF TF:M11275_1 Factor: XBP-1; motif: SRTGAYGTCAYS; match class: 1 0.0341152981762127 923 12 4 0.333333333333333 0.00433369447453954
TF TF:M03834 Factor: N-Myc; motif: GSSCACGYGS 0.0341468164133914 1414 40 9 0.225 0.00636492220650637
TF TF:M08266_1 Factor: ER71:Pax-5; motif: ACCGGAACYACGCWTSANTG; match class: 1 0.0342139186710703 8979 42 29 0.69047619047619 0.00322975832498051
TF TF:M02090 Factor: E2F-4; motif: GCGGGAAANA 0.0343554680911076 11966 78 60 0.769230769230769 0.00501420691960555
TF TF:M00017 Factor: ATF; motif: CNSTGACGTNNNYC 0.0346229270681015 7226 81 43 0.530864197530864 0.00595073346249654
TF TF:M11434_1 Factor: Elk-1; motif: NRSCGGAAGNN; match class: 1 0.0346229270681015 2935 37 13 0.351351351351351 0.00442930153321976
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.0346229270681015 7600 38 24 0.631578947368421 0.00315789473684211
TF TF:M11288_1 Factor: ATF-3; motif: GATGAYGTCATN; match class: 1 0.0346229270681015 1624 12 5 0.416666666666667 0.00307881773399015
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.0346229270681015 10107 20 17 0.85 0.00168200257247452
TF TF:M11601 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.035220405426415 14823 22 22 1 0.00148417999055522
TF TF:M09608 Factor: Erg; motif: NNACCGGAARTSN 0.035220405426415 8152 36 24 0.666666666666667 0.00294406280667321
TF TF:M02011_1 Factor: HES-1; motif: GSCACGMGMC; match class: 1 0.035220405426415 845 42 7 0.166666666666667 0.00828402366863905
TF TF:M08487_1 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG; match class: 1 0.035220405426415 8790 22 17 0.772727272727273 0.00193401592718999
TF TF:M08510 Factor: TEF-3:Fli-1; motif: ACCGGAAATGCC 0.0354392033537547 7360 35 22 0.628571428571429 0.00298913043478261
TF TF:M11078 Factor: TCFL5; motif: KCACGCGCNC 0.0355147810611422 1471 39 9 0.230769230769231 0.00611828687967369
TF TF:M10098 Factor: DP-1; motif: NRNNGGCGGGAANN 0.0355357186410091 7015 45 26 0.577777777777778 0.00370634354953671
TF TF:M07289 Factor: GKLF; motif: NNNRGGNGNGGSN 0.0355357186410091 14646 21 21 1 0.0014338385907415
TF TF:M01593 Factor: Zfx; motif: SNSCAGGCCKCGSCSS 0.0363429579109296 4163 4 4 1 0.000960845544078789
TF TF:M04698 Factor: GABP-alpha; motif: CACTTCCGG 0.0374476662755253 3196 27 11 0.407407407407407 0.00344180225281602
TF TF:M11397_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.0374476662755253 11731 21 19 0.904761904761905 0.00161964026937175
TF TF:M11296_1 Factor: jdp2; motif: NRTGAYGTCAYN; match class: 1 0.0374976070512247 967 12 4 0.333333333333333 0.00413650465356774
TF TF:M04515 Factor: E2F-1; motif: WWTGGCGCCAAA 0.0374976070512247 13334 42 37 0.880952380952381 0.00277486125693715
TF TF:M08941_1 Factor: C-JUN:FRA-2; motif: NRTGACGTMAT; match class: 1 0.0378659973071572 3353 19 9 0.473684210526316 0.0026841634357292
TF TF:M09641_1 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN; match class: 1 0.0383098893475851 991 37 7 0.189189189189189 0.0070635721493441
TF TF:M00981 Factor: CREB,; motif: NTGACGTNA 0.0383098893475851 8345 96 55 0.572916666666667 0.00659077291791492
TF TF:M01865 Factor: BTEB3; motif: BNRNGGGAGGNGT 0.0383098893475851 9899 25 20 0.8 0.00202040610162643
TF TF:M02014_1 Factor: HNF-3beta; motif: NTRTTTRYT; match class: 1 0.0383098893475851 224 23 3 0.130434782608696 0.0133928571428571
TF TF:M11217 Factor: CREB1; motif: NRTGACGYN 0.0383098893475851 2783 35 12 0.342857142857143 0.00431189363995688
TF TF:M10638_1 Factor: Nkx2-3; motif: NNCGTTRWS; match class: 1 0.0383098893475851 4099 19 10 0.526315789473684 0.00243961941937058
TF TF:M10991 Factor: lmx1b; motif: CTCGTTAA 0.0385720239445516 1589 44 10 0.227272727272727 0.00629326620516048
TF TF:M04110_1 Factor: RUNX3; motif: NRACCGCANWAACCRCAN; match class: 1 0.0386569382152242 3764 63 22 0.349206349206349 0.00584484590860786
TF TF:M11231 Factor: CREBL1; motif: GRTGACGTCAYC 0.0387489676694558 1057 35 7 0.2 0.00662251655629139
TF TF:M11224 Factor: CREM; motif: NRTGATGTCAYN 0.0387489676694558 3382 19 9 0.473684210526316 0.00266114725014784
TF TF:M04926 Factor: REST; motif: AAGGTGCT 0.0387489676694558 6325 40 22 0.55 0.00347826086956522
TF TF:M02036_1 Factor: WT1; motif: CGCCCCCNCN; match class: 1 0.0398382563192458 5290 18 11 0.611111111111111 0.00207939508506616
TF TF:M00956 Factor: AR; motif: NNNNNNRGNACRNNGTGTTCTNNNNNN 0.0398939747966231 2717 23 9 0.391304347826087 0.00331247699668752
TF TF:M10785 Factor: hoxa9; motif: RTCGTWANNN 0.0403185524961367 5632 63 29 0.46031746031746 0.00514914772727273
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.0404418346591445 10488 76 53 0.697368421052632 0.00505339435545385
TF TF:M01864_1 Factor: ATF-4; motif: KACGTCAKS; match class: 1 0.0404418346591445 1239 23 6 0.260869565217391 0.00484261501210654
TF TF:M01047 Factor: AP-2alphaA; motif: ANMGCCTNAGGCKNT 0.0404418346591445 9237 70 45 0.642857142857143 0.0048717115946736
TF TF:M01047_1 Factor: AP-2alphaA; motif: ANMGCCTNAGGCKNT; match class: 1 0.0404418346591445 9237 70 45 0.642857142857143 0.0048717115946736
TF TF:M12147_1 Factor: SP8; motif: RNCACGCCCMCN; match class: 1 0.0404418346591445 331 34 4 0.117647058823529 0.0120845921450151
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 0.0404418346591445 14997 22 22 1 0.0014669600586784
TF TF:M11535_1 Factor: E2F-4; motif: TTTTGGCGCCAWWN; match class: 1 0.0404418346591445 6532 65 33 0.507692307692308 0.0050520514390692
TF TF:M00652 Factor: NRF-1; motif: CGCATGCGCR 0.0404418346591445 1376 68 12 0.176470588235294 0.00872093023255814
TF TF:M04516 Factor: E2F-1; motif: TTTGGCGCCAAA 0.0404418346591445 11383 37 30 0.810810810810811 0.00263550909250637
TF TF:M04714 Factor: Elf-1; motif: ACTTCCGGG 0.0404418346591445 7798 30 20 0.666666666666667 0.00256476019492177
TF TF:M06948_1 Factor: Sp2; motif: TGGGCGCGCCCA; match class: 1 0.0405939812396333 6205 63 31 0.492063492063492 0.00499597099113618
TF TF:M11402 Factor: Fli-1; motif: NACCGGAARTN 0.0409458681455546 3885 40 16 0.4 0.00411840411840412
TF TF:M07265 Factor: Nrf2; motif: NNTGACTCAGCAN 0.0417802778065636 4867 22 12 0.545454545454545 0.00246558454900349
TF TF:M11306_1 Factor: ATF-2; motif: NRTGAYGTMAYN; match class: 1 0.041887951917336 1025 12 4 0.333333333333333 0.00390243902439024
TF TF:M00691_1 Factor: ATF-1; motif: CYYTGACGTCA; match class: 1 0.041887951917336 854 68 9 0.132352941176471 0.0105386416861827
TF TF:M11224_1 Factor: CREM; motif: NRTGATGTCAYN; match class: 1 0.041887951917336 1025 12 4 0.333333333333333 0.00390243902439024
TF TF:M01862 Factor: ATF-2; motif: NNNTGACGTNAN 0.0419302292398459 3230 96 27 0.28125 0.00835913312693498
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.0431400559970881 15072 22 22 1 0.00145966029723991
TF TF:M05755 Factor: ZNF718; motif: GTTAAGGARA 0.0431400559970881 103 53 3 0.0566037735849057 0.029126213592233
TF TF:M08313 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR 0.0432578166427283 15419 24 24 1 0.00155652117517349
TF TF:M03862_1 Factor: YB-1; motif: NNNNCCAATNN; match class: 1 0.0434397681162993 3120 5 4 0.8 0.00128205128205128
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 0.0434397681162993 10494 73 51 0.698630136986301 0.00485991995425958
TF TF:M11450 Factor: Elf-1; motif: NANSCGGAAGTR 0.0435465922011173 5601 27 15 0.555555555555556 0.00267809319764328
TF TF:M00982 Factor: KROX; motif: CCCGCCCCCRCCCC 0.0435465922011173 7815 19 14 0.736842105263158 0.0017914267434421
TF TF:M10088 Factor: TBP; motif: MTATAAAARS 0.0437782692280803 4934 12 8 0.666666666666667 0.0016214025131739
TF TF:M01073_1 Factor: HIC1; motif: NNNGGKTGCCCSNNNNNN; match class: 1 0.0437782692280803 762 8 3 0.375 0.00393700787401575
TF TF:M11254 Factor: AIBZIP; motif: GRTGAYGTCAYC 0.0441006828261485 1132 18 5 0.277777777777778 0.00441696113074205
TF TF:M10529 Factor: Sp1; motif: RGGGMGGRGSNGGGG 0.0445917433982331 6891 25 16 0.64 0.00232186910462923
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.0445917433982331 16244 42 41 0.976190476190476 0.00252400886481162
TF TF:M01299 Factor: MECP2; motif: CCGGNNTTWA 0.0447520162044452 5228 21 12 0.571428571428571 0.00229533282325937
TF TF:M00004_1 Factor: c-Myb; motif: NCNRNNGRCNGTTGGKGG; match class: 1 0.0450006950044383 1883 72 15 0.208333333333333 0.0079660116834838
TF TF:M04595 Factor: SALL2; motif: GGGTGGG 0.0453599823879737 13013 14 14 1 0.00107584722969338
TF TF:M11077 Factor: TCFL5; motif: KCACGCGCMC 0.0453599823879737 990 39 7 0.179487179487179 0.00707070707070707
TF TF:M11452 Factor: Elf-1; motif: NANGCGGAAGTR 0.0454460552967695 6276 27 16 0.592592592592593 0.00254939451880178
TF TF:M03923 Factor: SP8; motif: RCCACGCCCMCY 0.045660593167994 2843 3 3 1 0.00105522335561027
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.0457873655719128 10419 72 50 0.694444444444444 0.00479892504079086
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.0459801925705752 12747 71 57 0.802816901408451 0.00447164038597317
TF TF:M08965_1 Factor: NR1B1:RXR-GAMMA; motif: RRGGTCANNNNNRGGTCA; match class: 1 0.0459801925705752 615 62 7 0.112903225806452 0.0113821138211382
TF TF:M11216 Factor: CREB1; motif: NRTGATGTCAYN 0.0459801925705752 4287 19 10 0.526315789473684 0.00233263354327035
TF TF:M10885 Factor: PRX-2; motif: NKCGTTAN 0.0459801925705752 5715 55 26 0.472727272727273 0.00454943132108486
TF TF:M11018_1 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN; match class: 1 0.0459801925705752 15920 27 27 1 0.00169597989949749
TF TF:M09837 Factor: ZNF449; motif: NNNAGCCCARCC 0.0459801925705752 4264 25 12 0.48 0.00281425891181989
TF TF:M11222_1 Factor: CREB1; motif: NRTGAYGTCAYN; match class: 1 0.0459801925705752 1088 19 5 0.263157894736842 0.00459558823529412
TF TF:M10887 Factor: PRX-2; motif: NNCRTTAN 0.0459801925705752 5715 55 26 0.472727272727273 0.00454943132108486
TF TF:M00322 Factor: c-Myc:Max; motif: GCCAYGYGSN 0.0461805680564189 7873 36 23 0.638888888888889 0.00292137685761463
TF TF:M07426_1 Factor: Nur77; motif: AAAGGTCANNN; match class: 1 0.04683376461441 128 93 4 0.043010752688172 0.03125
TF TF:M04109 Factor: RUNX3; motif: NRACCGCAAACCGCAN 0.04683376461441 9770 21 17 0.80952380952381 0.00174002047082907
TF TF:M11696_1 Factor: MEF-2B1; motif: CCNWATWWRG; match class: 1 0.0476239811363721 898 67 9 0.134328358208955 0.010022271714922
TF TF:M03952_1 Factor: CDP; motif: TRATCRATAN; match class: 1 0.0478329993405562 1126 6 3 0.5 0.00266429840142096
TF TF:M09904 Factor: Elk-1; motif: RCCGGAAGTGN 0.0484136758905785 8164 37 24 0.648648648648649 0.00293973542381186
TF TF:M02036 Factor: WT1; motif: CGCCCCCNCN 0.0484136758905785 9767 18 15 0.833333333333333 0.00153578376164636
TF TF:M04107_1 Factor: RUNX2; motif: WRACCGCANWAACCGCAN; match class: 1 0.0484136758905785 6444 38 21 0.552631578947368 0.00325884543761639
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.0484136758905785 15268 73 66 0.904109589041096 0.00432276657060519
TF TF:M03567 Factor: Sp2; motif: NYSGCCCCGCCCCCY 0.0484136758905785 7710 72 40 0.555555555555556 0.00518806744487678
TF TF:M11385 Factor: ESE-1; motif: NTGTGCGGATGCN 0.0487957721183841 12232 17 16 0.941176470588235 0.0013080444735121
TF TF:M00056 Factor: myogenin; motif: CRSCTGTTBNNTTTGGCACGSNGCCARCH 0.0490818135093461 12374 38 32 0.842105263157895 0.00258606756101503
TF TF:M03896 Factor: EGR1; motif: NACGCCCACGCANW 0.0493734942332635 6129 21 13 0.619047619047619 0.00212106379507261
TF TF:M10086_1 Factor: TAFII250; motif: RARRWGGCGGMGGNGR; match class: 1 0.04952295727374 4153 96 32 0.333333333333333 0.00770527329641223
TF TF:M11828 Factor: LRH-1; motif: TCAAGGTCRYGACCTTGR 0.0495247520004334 10627 41 31 0.75609756097561 0.00291709795803143
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 0.0495247520004334 6334 63 31 0.492063492063492 0.0048942216608778
TF TF:M11289 Factor: ATF-3; motif: NRTGACGTCAYN 0.0495247520004334 4773 23 12 0.521739130434783 0.00251414204902577
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.0495504178632795 11116 18 16 0.888888888888889 0.00143936667866139
TF TF:M09765 Factor: SP1; motif: NRGKGGGCGGGGCN 0.049899073465791 7469 72 39 0.541666666666667 0.00522158254117017
TF TF:M01858 Factor: AP-2beta; motif: GCNNNGGSCNGVGGGN 0.049899073465791 7418 22 15 0.681818181818182 0.00202210838500944
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.0499275811809343 13270 96 77 0.802083333333333 0.00580256217030897
WP WP:WP2359 Parkin-Ubiquitin Proteasomal System pathway 0.000693895306960067 70 13 4 0.307692307692308 0.0571428571428571
WP WP:WP382 MAPK Signaling Pathway 0.00122011440292783 249 18 6 0.333333333333333 0.0240963855421687
WP WP:WP2884 NRF2 pathway 0.00139695545238215 145 4 3 0.75 0.0206896551724138
WP WP:WP2882 Nuclear Receptors Meta-Pathway 0.00673928052674116 321 21 6 0.285714285714286 0.0186915887850467
WP WP:WP3888 VEGFA-VEGFR2 Signaling Pathway 0.00682824390756412 437 23 7 0.304347826086957 0.0160183066361556
WP WP:WP1772 Apoptosis Modulation and Signaling 0.032968103345477 93 18 3 0.166666666666667 0.032258064516129
WP WP:WP2873 Aryl Hydrocarbon Receptor Pathway 0.0442191472851956 48 40 3 0.075 0.0625

pM12 transcription factor target enrichment of top program genes

TF enrichment of pM12
TFs corrosponding to activation of pM12. (Left) pearson correlation of TF expression and gene expression program activatity in Myeloid cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.