pEpiTd27 program activity among Epithelial cells

Activation of pEpiTd27
pEpiTd27 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpiTd27 by different cell subtypes
pEpiTd27 gene program activation among cells of different subtypes (Epithelial cells).

pEpiTd27 top program genes

Top genes of pEpiTd27 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpiTd27 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpiTd27
pEpiTd27 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:7557 LGR4-RSPO supercomplex 0.0200569702655294 10 119 4 0.0336134453781513 0.4
GO:BP GO:0007015 actin filament organization 0.000130298419643825 445 116 15 0.129310344827586 0.0337078651685393
GO:BP GO:1903829 positive regulation of cellular protein localization 0.000130298419643825 303 130 13 0.1 0.0429042904290429
GO:BP GO:0060341 regulation of cellular localization 0.000130298419643825 851 130 22 0.169230769230769 0.0258519388954172
GO:BP GO:0006099 tricarboxylic acid cycle 0.000130298419643825 36 140 6 0.0428571428571429 0.166666666666667
GO:BP GO:0030029 actin filament-based process 0.000130298419643825 808 119 20 0.168067226890756 0.0247524752475248
GO:BP GO:0110053 regulation of actin filament organization 0.000130298419643825 284 116 12 0.103448275862069 0.0422535211267606
GO:BP GO:0032535 regulation of cellular component size 0.000130298419643825 388 116 14 0.120689655172414 0.0360824742268041
GO:BP GO:0032970 regulation of actin filament-based process 0.000130298419643825 406 119 15 0.126050420168067 0.0369458128078818
GO:BP GO:0030832 regulation of actin filament length 0.000147649517277542 194 116 10 0.0862068965517241 0.0515463917525773
GO:BP GO:0008064 regulation of actin polymerization or depolymerization 0.000147649517277542 193 116 10 0.0862068965517241 0.0518134715025907
GO:BP GO:0051493 regulation of cytoskeleton organization 0.000147649517277542 531 119 16 0.134453781512605 0.0301318267419962
GO:BP GO:0032880 regulation of protein localization 0.000178426571013618 922 130 22 0.169230769230769 0.0238611713665944
GO:BP GO:0030036 actin cytoskeleton organization 0.00020694709922671 709 119 18 0.151260504201681 0.0253878702397743
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.00020694709922671 366 119 13 0.109243697478992 0.0355191256830601
GO:BP GO:0097435 supramolecular fiber organization 0.000215231166084335 734 116 18 0.155172413793103 0.0245231607629428
GO:BP GO:0090066 regulation of anatomical structure size 0.000233746623083368 518 116 15 0.129310344827586 0.028957528957529
GO:BP GO:0008154 actin polymerization or depolymerization 0.000321121764739319 223 116 10 0.0862068965517241 0.0448430493273543
GO:BP GO:0045010 actin nucleation 0.000321121764739319 57 116 6 0.0517241379310345 0.105263157894737
GO:BP GO:0006793 phosphorus metabolic process 0.000328302649953851 3114 140 47 0.335714285714286 0.0150931278098908
GO:BP GO:0030833 regulation of actin filament polymerization 0.000348485448152052 177 116 9 0.0775862068965517 0.0508474576271186
GO:BP GO:0051495 positive regulation of cytoskeleton organization 0.000377895779637027 231 116 10 0.0862068965517241 0.0432900432900433
GO:BP GO:0072350 tricarboxylic acid metabolic process 0.000404084544465926 14 133 4 0.0300751879699248 0.285714285714286
GO:BP GO:0044281 small molecule metabolic process 0.00041263021101242 1921 140 34 0.242857142857143 0.0176991150442478
GO:BP GO:1903827 regulation of cellular protein localization 0.000486567862979476 572 130 16 0.123076923076923 0.027972027972028
GO:BP GO:0006101 citrate metabolic process 0.000518439389632436 5 133 3 0.0225563909774436 0.6
GO:BP GO:0030041 actin filament polymerization 0.000574782654815551 196 116 9 0.0775862068965517 0.0459183673469388
GO:BP GO:0030838 positive regulation of actin filament polymerization 0.000574782654815551 104 116 7 0.0603448275862069 0.0673076923076923
GO:BP GO:0007010 cytoskeleton organization 0.000574782654815551 1423 119 25 0.210084033613445 0.0175685172171469
GO:BP GO:0016482 cytosolic transport 0.000620473001713174 168 137 9 0.0656934306569343 0.0535714285714286
GO:BP GO:0009060 aerobic respiration 0.000649384857194752 89 140 7 0.05 0.0786516853932584
GO:BP GO:0034314 Arp2/3 complex-mediated actin nucleation 0.000672081238794698 41 116 5 0.0431034482758621 0.121951219512195
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.000687092795533822 387 116 12 0.103448275862069 0.0310077519379845
GO:BP GO:0055086 nucleobase-containing small molecule metabolic process 0.000687092795533822 629 111 15 0.135135135135135 0.0238473767885533
GO:BP GO:0010638 positive regulation of organelle organization 0.000687092795533822 603 116 15 0.129310344827586 0.0248756218905473
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.000687092795533822 3087 106 37 0.349056603773585 0.0119857466796242
GO:BP GO:0033043 regulation of organelle organization 0.000691780740725109 1203 134 24 0.17910447761194 0.0199501246882793
GO:BP GO:0032528 microvillus organization 0.000691780740725109 24 97 4 0.0412371134020619 0.166666666666667
GO:BP GO:0071702 organic substance transport 0.000805041461851088 2766 132 40 0.303030303030303 0.0144613159797542
GO:BP GO:0071786 endoplasmic reticulum tubular network organization 0.000811168607103074 18 139 4 0.0287769784172662 0.222222222222222
GO:BP GO:1902905 positive regulation of supramolecular fiber organization 0.000819058416985618 214 116 9 0.0775862068965517 0.0420560747663551
GO:BP GO:0006820 anion transport 0.000874678820000844 2889 132 41 0.310606060606061 0.0141917618553133
GO:BP GO:0090407 organophosphate biosynthetic process 0.000875559138432373 598 136 16 0.117647058823529 0.0267558528428094
GO:BP GO:0006996 organelle organization 0.000884534146588954 4104 119 48 0.403361344537815 0.0116959064327485
GO:BP GO:0019637 organophosphate metabolic process 0.00109021768894306 1041 91 17 0.186813186813187 0.0163304514889529
GO:BP GO:0065008 regulation of biological quality 0.00109021768894306 4131 116 47 0.405172413793103 0.0113773904623578
GO:BP GO:0070849 response to epidermal growth factor 0.00125226853376126 49 119 5 0.0420168067226891 0.102040816326531
GO:BP GO:0008104 protein localization 0.00136698665546172 2770 131 39 0.297709923664122 0.0140794223826715
GO:BP GO:0032271 regulation of protein polymerization 0.00148856624921007 236 116 9 0.0775862068965517 0.038135593220339
GO:BP GO:0033036 macromolecule localization 0.00151019351909453 3218 131 43 0.32824427480916 0.0133623368551896
GO:BP GO:0071071 regulation of phospholipid biosynthetic process 0.00156899716638679 20 51 3 0.0588235294117647 0.15
GO:BP GO:1901137 carbohydrate derivative biosynthetic process 0.00179816190031045 686 128 16 0.125 0.0233236151603499
GO:BP GO:0048013 ephrin receptor signaling pathway 0.00218991927941187 88 126 6 0.0476190476190476 0.0681818181818182
GO:BP GO:0032273 positive regulation of protein polymerization 0.00218991927941187 141 116 7 0.0603448275862069 0.049645390070922
GO:BP GO:0032530 regulation of microvillus organization 0.00252045508417407 13 97 3 0.0309278350515464 0.230769230769231
GO:BP GO:0043086 negative regulation of catalytic activity 0.00252045508417407 851 119 17 0.142857142857143 0.0199764982373678
GO:BP GO:0051125 regulation of actin nucleation 0.00265685335744717 31 116 4 0.0344827586206897 0.129032258064516
GO:BP GO:0046907 intracellular transport 0.0028313173694181 1767 137 29 0.211678832116788 0.0164119977362762
GO:BP GO:0006790 sulfur compound metabolic process 0.00285464102770846 386 62 8 0.129032258064516 0.0207253886010363
GO:BP GO:1901135 carbohydrate derivative metabolic process 0.00291405907655354 1145 128 21 0.1640625 0.0183406113537118
GO:BP GO:0034032 purine nucleoside bisphosphate metabolic process 0.00335036052352493 141 128 7 0.0546875 0.049645390070922
GO:BP GO:0033875 ribonucleoside bisphosphate metabolic process 0.00335036052352493 141 128 7 0.0546875 0.049645390070922
GO:BP GO:0033865 nucleoside bisphosphate metabolic process 0.00335036052352493 141 128 7 0.0546875 0.049645390070922
GO:BP GO:0006811 ion transport 0.00335036052352493 3661 132 46 0.348484848484849 0.0125648729855231
GO:BP GO:0010256 endomembrane system organization 0.00335036052352493 484 98 11 0.112244897959184 0.0227272727272727
GO:BP GO:0051128 regulation of cellular component organization 0.00335036052352493 2412 135 35 0.259259259259259 0.0145107794361526
GO:BP GO:0006810 transport 0.00376154393287646 5224 132 59 0.446969696969697 0.0112940275650842
GO:BP GO:0030866 cortical actin cytoskeleton organization 0.00413091609454856 41 102 4 0.0392156862745098 0.0975609756097561
GO:BP GO:0071705 nitrogen compound transport 0.00418867574617864 2322 131 33 0.251908396946565 0.0142118863049096
GO:BP GO:0072659 protein localization to plasma membrane 0.00440767645733811 283 117 9 0.0769230769230769 0.0318021201413428
GO:BP GO:0051641 cellular localization 0.00472588111824681 3541 131 44 0.33587786259542 0.0124258683987574
GO:BP GO:2000117 negative regulation of cysteine-type endopeptidase activity 0.0052097907771836 89 97 5 0.0515463917525773 0.0561797752808989
GO:BP GO:0006879 cellular iron ion homeostasis 0.00535277065711147 69 127 5 0.0393700787401575 0.072463768115942
GO:BP GO:0044092 negative regulation of molecular function 0.00535277065711147 1219 119 20 0.168067226890756 0.0164068908941756
GO:BP GO:0051130 positive regulation of cellular component organization 0.00535277065711147 1153 135 21 0.155555555555556 0.018213356461405
GO:BP GO:0030835 negative regulation of actin filament depolymerization 0.00535277065711147 48 97 4 0.0412371134020619 0.0833333333333333
GO:BP GO:0009150 purine ribonucleotide metabolic process 0.00535277065711147 414 103 10 0.0970873786407767 0.0241545893719807
GO:BP GO:0051258 protein polymerization 0.00636826987061276 305 116 9 0.0775862068965517 0.0295081967213115
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.00648675147077783 263 135 9 0.0666666666666667 0.0342205323193916
GO:BP GO:0002028 regulation of sodium ion transport 0.00648675147077783 87 106 5 0.0471698113207547 0.0574712643678161
GO:BP GO:0050892 intestinal absorption 0.00662099766339919 40 127 4 0.031496062992126 0.1
GO:BP GO:0051179 localization 0.00662099766339919 6901 132 71 0.537878787878788 0.0102883640052166
GO:BP GO:0051234 establishment of localization 0.00662099766339919 5372 132 59 0.446969696969697 0.0109828741623232
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.00662099766339919 460 135 12 0.0888888888888889 0.0260869565217391
GO:BP GO:0048732 gland development 0.00662099766339919 436 102 10 0.0980392156862745 0.0229357798165138
GO:BP GO:0009259 ribonucleotide metabolic process 0.00662099766339919 431 103 10 0.0970873786407767 0.0232018561484919
GO:BP GO:1903725 regulation of phospholipid metabolic process 0.00665529458325619 39 51 3 0.0588235294117647 0.0769230769230769
GO:BP GO:1901615 organic hydroxy compound metabolic process 0.00665529458325619 571 51 8 0.156862745098039 0.0140105078809107
GO:BP GO:0016241 regulation of macroautophagy 0.00735029861298197 161 136 7 0.0514705882352941 0.0434782608695652
GO:BP GO:0019693 ribose phosphate metabolic process 0.00735029861298197 441 103 10 0.0970873786407767 0.0226757369614512
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.00735029861298197 540 135 13 0.0962962962962963 0.0240740740740741
GO:BP GO:0034613 cellular protein localization 0.00735029861298197 2014 131 29 0.221374045801527 0.0143992055610725
GO:BP GO:0051346 negative regulation of hydrolase activity 0.00735029861298197 470 97 10 0.103092783505155 0.0212765957446809
GO:BP GO:0071364 cellular response to epidermal growth factor stimulus 0.00735029861298197 45 119 4 0.0336134453781513 0.0888888888888889
GO:BP GO:0009101 glycoprotein biosynthetic process 0.00735029861298197 347 29 5 0.172413793103448 0.0144092219020173
GO:BP GO:0034330 cell junction organization 0.00735029861298197 722 130 15 0.115384615384615 0.0207756232686981
GO:BP GO:0070727 cellular macromolecule localization 0.00757401894227524 2024 131 29 0.221374045801527 0.0143280632411067
GO:BP GO:0008654 phospholipid biosynthetic process 0.00757401894227524 274 136 9 0.0661764705882353 0.0328467153284672
GO:BP GO:0010765 positive regulation of sodium ion transport 0.00759706636402188 35 62 3 0.0483870967741935 0.0857142857142857
GO:BP GO:0006163 purine nucleotide metabolic process 0.00791598949139606 450 103 10 0.0970873786407767 0.0222222222222222
GO:BP GO:0030834 regulation of actin filament depolymerization 0.00791598949139606 57 97 4 0.0412371134020619 0.0701754385964912
GO:BP GO:0048268 clathrin coat assembly 0.00793457350988943 18 126 3 0.0238095238095238 0.166666666666667
GO:BP GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 0.00811721162671904 760 126 15 0.119047619047619 0.0197368421052632
GO:BP GO:0009117 nucleotide metabolic process 0.00826944941846118 544 103 11 0.106796116504854 0.0202205882352941
GO:BP GO:0016043 cellular component organization 0.00854996425503266 6566 119 62 0.521008403361345 0.00944258300335059
GO:BP GO:0098927 vesicle-mediated transport between endosomal compartments 0.00854996425503266 42 137 4 0.0291970802919708 0.0952380952380952
GO:BP GO:0072583 clathrin-dependent endocytosis 0.00870249235499519 46 126 4 0.0317460317460317 0.0869565217391304
GO:BP GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 0.0091343248198159 21 116 3 0.0258620689655172 0.142857142857143
GO:BP GO:0032879 regulation of localization 0.0091343248198159 2872 119 34 0.285714285714286 0.0118384401114206
GO:BP GO:0006753 nucleoside phosphate metabolic process 0.00913706405617791 555 103 11 0.106796116504854 0.0198198198198198
GO:BP GO:0030042 actin filament depolymerization 0.00957845696696088 62 97 4 0.0412371134020619 0.0645161290322581
GO:BP GO:1990778 protein localization to cell periphery 0.00957845696696088 338 117 9 0.0769230769230769 0.0266272189349112
GO:BP GO:0033673 negative regulation of kinase activity 0.00957845696696088 275 114 8 0.0701754385964912 0.0290909090909091
GO:BP GO:0055072 iron ion homeostasis 0.00957845696696088 86 127 5 0.0393700787401575 0.0581395348837209
GO:BP GO:0072521 purine-containing compound metabolic process 0.00978356677429146 473 103 10 0.0970873786407767 0.0211416490486258
GO:BP GO:0030879 mammary gland development 0.00982219912213641 140 79 5 0.0632911392405063 0.0357142857142857
GO:BP GO:0038127 ERBB signaling pathway 0.0104109043692794 145 119 6 0.0504201680672269 0.0413793103448276
GO:BP GO:1901564 organonitrogen compound metabolic process 0.0104109043692794 6792 130 68 0.523076923076923 0.0100117785630153
GO:BP GO:0061024 membrane organization 0.010768281437457 973 126 17 0.134920634920635 0.0174717368961973
GO:BP GO:0015980 energy derivation by oxidation of organic compounds 0.010768281437457 289 140 9 0.0642857142857143 0.0311418685121107
GO:BP GO:0051261 protein depolymerization 0.010768281437457 117 97 5 0.0515463917525773 0.0427350427350427
GO:BP GO:0150104 transport across blood-brain barrier 0.0110501692167204 87 31 3 0.0967741935483871 0.0344827586206897
GO:BP GO:0030865 cortical cytoskeleton organization 0.0110501692167204 63 102 4 0.0392156862745098 0.0634920634920635
GO:BP GO:0008610 lipid biosynthetic process 0.0112346502090134 740 136 15 0.110294117647059 0.0202702702702703
GO:BP GO:0010232 vascular transport 0.0112346502090134 88 31 3 0.0967741935483871 0.0340909090909091
GO:BP GO:0005975 carbohydrate metabolic process 0.0116408070007866 635 80 10 0.125 0.015748031496063
GO:BP GO:0022607 cellular component assembly 0.0116444507129653 3010 139 39 0.280575539568345 0.0129568106312292
GO:BP GO:0009100 glycoprotein metabolic process 0.0124785410587079 424 29 5 0.172413793103448 0.0117924528301887
GO:BP GO:0043270 positive regulation of ion transport 0.0126560207358946 694 102 12 0.117647058823529 0.0172910662824208
GO:BP GO:0051222 positive regulation of protein transport 0.0129310225856559 329 102 8 0.0784313725490196 0.0243161094224924
GO:BP GO:0010634 positive regulation of epithelial cell migration 0.0132055127049371 181 102 6 0.0588235294117647 0.0331491712707182
GO:BP GO:0050790 regulation of catalytic activity 0.0132338868005762 2545 106 28 0.264150943396226 0.0110019646365422
GO:BP GO:0051017 actin filament bundle assembly 0.0132808550417492 161 115 6 0.0521739130434783 0.0372670807453416
GO:BP GO:0008219 cell death 0.0136089345497465 2292 106 26 0.245283018867925 0.0113438045375218
GO:BP GO:0106027 neuron projection organization 0.0138226054204253 92 76 4 0.0526315789473684 0.0434782608695652
GO:BP GO:0043436 oxoacid metabolic process 0.0139621091624885 1057 51 10 0.196078431372549 0.00946073793755913
GO:BP GO:0061572 actin filament bundle organization 0.0139621091624885 164 115 6 0.0521739130434783 0.0365853658536585
GO:BP GO:0008306 associative learning 0.0141623985315843 78 91 4 0.043956043956044 0.0512820512820513
GO:BP GO:0015748 organophosphate ester transport 0.0143442889656893 136 23 3 0.130434782608696 0.0220588235294118
GO:BP GO:0051050 positive regulation of transport 0.0143442889656893 923 102 14 0.137254901960784 0.0151679306608884
GO:BP GO:1903649 regulation of cytoplasmic transport 0.0145198690964487 27 116 3 0.0258620689655172 0.111111111111111
GO:BP GO:0051649 establishment of localization in cell 0.0146007083166777 2813 131 35 0.267175572519084 0.0124422324920014
GO:BP GO:0071840 cellular component organization or biogenesis 0.0147731704365637 6760 119 62 0.521008403361345 0.00917159763313609
GO:BP GO:1901880 negative regulation of protein depolymerization 0.014852126704289 75 97 4 0.0412371134020619 0.0533333333333333
GO:BP GO:0045333 cellular respiration 0.0151369757281338 192 140 7 0.05 0.0364583333333333
GO:BP GO:1904951 positive regulation of establishment of protein localization 0.0151369757281338 345 102 8 0.0784313725490196 0.0231884057971014
GO:BP GO:0015833 peptide transport 0.0151369757281338 1971 137 28 0.204379562043796 0.0142059868087265
GO:BP GO:0072657 protein localization to membrane 0.0151369757281338 665 126 13 0.103174603174603 0.0195488721804511
GO:BP GO:1905145 cellular response to acetylcholine 0.0152339354249619 31 105 3 0.0285714285714286 0.0967741935483871
GO:BP GO:1905144 response to acetylcholine 0.0152339354249619 31 105 3 0.0285714285714286 0.0967741935483871
GO:BP GO:0090162 establishment of epithelial cell polarity 0.015296155921451 32 102 3 0.0294117647058824 0.09375
GO:BP GO:0051348 negative regulation of transferase activity 0.0153059692892965 310 114 8 0.0701754385964912 0.0258064516129032
GO:BP GO:0019220 regulation of phosphate metabolic process 0.0153788755045362 1645 95 19 0.2 0.0115501519756839
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.0153788755045362 1645 95 19 0.2 0.0115501519756839
GO:BP GO:0006082 organic acid metabolic process 0.0153788755045362 1090 51 10 0.196078431372549 0.00917431192660551
GO:BP GO:1990776 response to angiotensin 0.0154517710104105 28 119 3 0.0252100840336134 0.107142857142857
GO:BP GO:0042982 amyloid precursor protein metabolic process 0.0165370238766198 96 139 5 0.0359712230215827 0.0520833333333333
GO:BP GO:0048522 positive regulation of cellular process 0.0165530837592961 5757 102 48 0.470588235294118 0.00833767587285044
GO:BP GO:0039694 viral RNA genome replication 0.0165530837592961 36 95 3 0.0315789473684211 0.0833333333333333
GO:BP GO:0007030 Golgi organization 0.0165721247406398 147 137 6 0.0437956204379562 0.0408163265306122
GO:BP GO:1901566 organonitrogen compound biosynthetic process 0.0168096555686663 1853 73 17 0.232876712328767 0.00917431192660551
GO:BP GO:0098771 inorganic ion homeostasis 0.0168096555686663 761 127 14 0.110236220472441 0.0183968462549277
GO:BP GO:0120035 regulation of plasma membrane bounded cell projection organization 0.0168419347296122 638 102 11 0.107843137254902 0.0172413793103448
GO:BP GO:0043549 regulation of kinase activity 0.0168419347296122 921 130 16 0.123076923076923 0.0173724212812161
GO:BP GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0169744207832058 81 97 4 0.0412371134020619 0.0493827160493827
GO:BP GO:0006091 generation of precursor metabolites and energy 0.0169809973569952 538 140 12 0.0857142857142857 0.0223048327137546
GO:BP GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 0.0169809973569952 135 101 5 0.0495049504950495 0.037037037037037
GO:BP GO:0042886 amide transport 0.0169809973569952 2007 137 28 0.204379562043796 0.0139511709018435
GO:BP GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 0.0169809973569952 135 101 5 0.0495049504950495 0.037037037037037
GO:BP GO:0009649 entrainment of circadian clock 0.0171690136561328 34 105 3 0.0285714285714286 0.0882352941176471
GO:BP GO:0016192 vesicle-mediated transport 0.0171690136561328 2180 139 30 0.215827338129496 0.0137614678899083
GO:BP GO:0051049 regulation of transport 0.0172197968496112 1809 130 25 0.192307692307692 0.0138197899391929
GO:BP GO:0038094 Fc-gamma receptor signaling pathway 0.0173280466980289 137 101 5 0.0495049504950495 0.0364963503649635
GO:BP GO:1902745 positive regulation of lamellipodium organization 0.0173280466980289 37 97 3 0.0309278350515464 0.0810810810810811
GO:BP GO:0006469 negative regulation of protein kinase activity 0.0176714621685816 251 114 7 0.0614035087719298 0.0278884462151394
GO:BP GO:0051223 regulation of protein transport 0.0176714621685816 586 130 12 0.0923076923076923 0.0204778156996587
GO:BP GO:0050808 synapse organization 0.0176714621685816 428 130 10 0.0769230769230769 0.0233644859813084
GO:BP GO:0032388 positive regulation of intracellular transport 0.018388149131401 229 92 6 0.0652173913043478 0.0262008733624454
GO:BP GO:0044087 regulation of cellular component biogenesis 0.0183903447916348 990 135 17 0.125925925925926 0.0171717171717172
GO:BP GO:0015850 organic hydroxy compound transport 0.0185720285375548 276 14 3 0.214285714285714 0.0108695652173913
GO:BP GO:0019725 cellular homeostasis 0.0186433846462999 981 113 15 0.132743362831858 0.0152905198776758
GO:BP GO:0015031 protein transport 0.0187674463705398 1929 137 27 0.197080291970803 0.0139968895800933
GO:BP GO:0002431 Fc receptor mediated stimulatory signaling pathway 0.0187674463705398 141 101 5 0.0495049504950495 0.0354609929078014
GO:BP GO:0031344 regulation of cell projection organization 0.0187674463705398 656 102 11 0.107843137254902 0.0167682926829268
GO:BP GO:0043242 negative regulation of protein-containing complex disassembly 0.0187855667596386 86 97 4 0.0412371134020619 0.0465116279069767
GO:BP GO:0016310 phosphorylation 0.0187855667596386 2138 106 24 0.226415094339623 0.0112254443405051
GO:BP GO:0043269 regulation of ion transport 0.0187855667596386 1379 116 19 0.163793103448276 0.0137781000725163
GO:BP GO:0043933 protein-containing complex subunit organization 0.0189263010742657 1963 135 27 0.2 0.0137544574630667
GO:BP GO:0065009 regulation of molecular function 0.0192697044347965 3221 106 32 0.30188679245283 0.00993480285625582
GO:BP GO:0034329 cell junction assembly 0.0195736347788375 438 130 10 0.0769230769230769 0.0228310502283105
GO:BP GO:0048666 neuron development 0.0206425720884285 1149 119 17 0.142857142857143 0.0147954743255004
GO:BP GO:0034033 purine nucleoside bisphosphate biosynthetic process 0.0206425720884285 68 128 4 0.03125 0.0588235294117647
GO:BP GO:0042060 wound healing 0.0206425720884285 549 105 10 0.0952380952380952 0.0182149362477231
GO:BP GO:0046916 cellular transition metal ion homeostasis 0.0206425720884285 116 127 5 0.0393700787401575 0.0431034482758621
GO:BP GO:0034030 ribonucleoside bisphosphate biosynthetic process 0.0206425720884285 68 128 4 0.03125 0.0588235294117647
GO:BP GO:0032386 regulation of intracellular transport 0.0206425720884285 367 130 9 0.0692307692307692 0.0245231607629428
GO:BP GO:0033866 nucleoside bisphosphate biosynthetic process 0.0206425720884285 68 128 4 0.03125 0.0588235294117647
GO:BP GO:1901879 regulation of protein depolymerization 0.0207030748024987 90 97 4 0.0412371134020619 0.0444444444444444
GO:BP GO:0060119 inner ear receptor cell development 0.0212079816204002 47 86 3 0.0348837209302326 0.0638297872340425
GO:BP GO:0070201 regulation of establishment of protein localization 0.0217718976622285 611 130 12 0.0923076923076923 0.0196399345335516
GO:BP GO:0030705 cytoskeleton-dependent intracellular transport 0.0217718976622285 202 75 5 0.0666666666666667 0.0247524752475248
GO:BP GO:0008542 visual learning 0.0217718976622285 45 91 3 0.032967032967033 0.0666666666666667
GO:BP GO:0010033 response to organic substance 0.0222725906743512 3412 110 34 0.309090909090909 0.00996483001172333
GO:BP GO:0050801 ion homeostasis 0.022461481298207 808 113 13 0.115044247787611 0.0160891089108911
GO:BP GO:0033572 transferrin transport 0.0228341148255113 36 117 3 0.0256410256410256 0.0833333333333333
GO:BP GO:0090087 regulation of peptide transport 0.0231630133798478 618 130 12 0.0923076923076923 0.0194174757281553
GO:BP GO:0051693 actin filament capping 0.0234248657488154 44 97 3 0.0309278350515464 0.0681818181818182
GO:BP GO:0009152 purine ribonucleotide biosynthetic process 0.0237213524178136 179 128 6 0.046875 0.0335195530726257
GO:BP GO:0007623 circadian rhythm 0.0237957295903602 219 105 6 0.0571428571428571 0.0273972602739726
GO:BP GO:0044070 regulation of anion transport 0.0239923976751135 896 116 14 0.120689655172414 0.015625
GO:BP GO:0032801 receptor catabolic process 0.0244700600647387 35 126 3 0.0238095238095238 0.0857142857142857
GO:BP GO:0061462 protein localization to lysosome 0.0244700600647387 46 95 3 0.0315789473684211 0.0652173913043478
GO:BP GO:0009611 response to wounding 0.0244700600647387 674 105 11 0.104761904761905 0.0163204747774481
GO:BP GO:0015711 organic anion transport 0.0253813765618752 386 42 5 0.119047619047619 0.0129533678756477
GO:BP GO:0051094 positive regulation of developmental process 0.0258392908699976 1341 97 16 0.164948453608247 0.0119313944817301
GO:BP GO:0042306 regulation of protein import into nucleus 0.0259765013257708 62 73 3 0.0410958904109589 0.0483870967741935
GO:BP GO:0030048 actin filament-based movement 0.0259765013257708 152 106 5 0.0471698113207547 0.0328947368421053
GO:BP GO:0007632 visual behavior 0.025989343981172 50 91 3 0.032967032967033 0.06
GO:BP GO:2000249 regulation of actin cytoskeleton reorganization 0.025989343981172 40 114 3 0.0263157894736842 0.075
GO:BP GO:0019752 carboxylic acid metabolic process 0.025989343981172 1024 51 9 0.176470588235294 0.0087890625
GO:BP GO:0051656 establishment of organelle localization 0.0261872801639554 445 93 8 0.0860215053763441 0.0179775280898876
GO:BP GO:0008202 steroid metabolic process 0.0263693154181748 342 14 3 0.214285714285714 0.0087719298245614
GO:BP GO:0042325 regulation of phosphorylation 0.0263693154181748 1431 135 21 0.155555555555556 0.0146750524109015
GO:BP GO:0030641 regulation of cellular pH 0.0264761203065973 95 103 4 0.0388349514563107 0.0421052631578947
GO:BP GO:0060997 dendritic spine morphogenesis 0.0266583238006515 61 76 3 0.0394736842105263 0.0491803278688525
GO:BP GO:1903793 positive regulation of anion transport 0.0266583238006515 504 102 9 0.0882352941176471 0.0178571428571429
GO:BP GO:0006629 lipid metabolic process 0.0266583238006515 1457 18 6 0.333333333333333 0.00411805078929307
GO:BP GO:0042987 amyloid precursor protein catabolic process 0.0266774140117498 71 139 4 0.0287769784172662 0.0563380281690141
GO:BP GO:0045936 negative regulation of phosphate metabolic process 0.0267466722874616 543 114 10 0.087719298245614 0.0184162062615101
GO:BP GO:0044085 cellular component biogenesis 0.0267466722874616 3257 139 39 0.280575539568345 0.0119742093951489
GO:BP GO:0055082 cellular chemical homeostasis 0.0267466722874616 841 113 13 0.115044247787611 0.0154577883472057
GO:BP GO:1905477 positive regulation of protein localization to membrane 0.0267466722874616 131 126 5 0.0396825396825397 0.0381679389312977
GO:BP GO:0051129 negative regulation of cellular component organization 0.0267466722874616 759 7 3 0.428571428571429 0.00395256916996047
GO:BP GO:0090316 positive regulation of intracellular protein transport 0.0267466722874616 186 130 6 0.0461538461538462 0.032258064516129
GO:BP GO:0051640 organelle localization 0.0267466722874616 668 93 10 0.10752688172043 0.0149700598802395
GO:BP GO:0051248 negative regulation of protein metabolic process 0.0267508822560268 1151 114 16 0.140350877192982 0.0139009556907037
GO:BP GO:1904589 regulation of protein import 0.0268619721604913 65 73 3 0.0410958904109589 0.0461538461538462
GO:BP GO:0010563 negative regulation of phosphorus metabolic process 0.0268619721604913 544 114 10 0.087719298245614 0.0183823529411765
GO:BP GO:0051489 regulation of filopodium assembly 0.0269906674691655 47 102 3 0.0294117647058824 0.0638297872340425
GO:BP GO:0042592 homeostatic process 0.0269906674691655 1981 113 23 0.20353982300885 0.0116102978293791
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0270728653397273 253 97 6 0.0618556701030928 0.0237154150197628
GO:BP GO:1900180 regulation of protein localization to nucleus 0.0270728653397273 139 73 4 0.0547945205479452 0.0287769784172662
GO:BP GO:0043244 regulation of protein-containing complex disassembly 0.0270728653397273 125 134 5 0.0373134328358209 0.04
GO:BP GO:0065003 protein-containing complex assembly 0.0270728653397273 1680 117 21 0.179487179487179 0.0125
GO:BP GO:0009260 ribonucleotide biosynthetic process 0.0274640264619239 192 128 6 0.046875 0.03125
GO:BP GO:0060996 dendritic spine development 0.0275393884839484 100 102 4 0.0392156862745098 0.04
GO:BP GO:0016236 macroautophagy 0.0276377719954355 312 136 8 0.0588235294117647 0.0256410256410256
GO:BP GO:0045184 establishment of protein localization 0.0278201492138326 2035 137 27 0.197080291970803 0.0132678132678133
GO:BP GO:0022612 gland morphogenesis 0.0280559105761268 120 86 4 0.0465116279069767 0.0333333333333333
GO:BP GO:0031175 neuron projection development 0.0282892986488659 1012 119 15 0.126050420168067 0.0148221343873518
GO:BP GO:0032922 circadian regulation of gene expression 0.0282949565210088 67 74 3 0.0405405405405405 0.0447761194029851
GO:BP GO:0048518 positive regulation of biological process 0.0284692842306696 6363 102 50 0.490196078431373 0.00785792865000786
GO:BP GO:0050793 regulation of developmental process 0.0287726253777009 2605 130 31 0.238461538461538 0.0119001919385797
GO:BP GO:0012501 programmed cell death 0.0290875194354022 2143 106 23 0.216981132075472 0.0107326178254783
GO:BP GO:0061180 mammary gland epithelium development 0.0290875194354022 69 73 3 0.0410958904109589 0.0434782608695652
GO:BP GO:1905475 regulation of protein localization to membrane 0.0297038858414099 201 126 6 0.0476190476190476 0.0298507462686567
GO:BP GO:0006885 regulation of pH 0.0297038858414099 103 103 4 0.0388349514563107 0.0388349514563107
GO:BP GO:0055076 transition metal ion homeostasis 0.0300458736713003 138 127 5 0.0393700787401575 0.036231884057971
GO:BP GO:0046390 ribose phosphate biosynthetic process 0.0301076041561439 199 128 6 0.046875 0.0301507537688442
GO:BP GO:0006814 sodium ion transport 0.0302348087562816 241 106 6 0.0566037735849057 0.024896265560166
GO:BP GO:0048771 tissue remodeling 0.0304659834043202 186 95 5 0.0526315789473684 0.0268817204301075
GO:BP GO:0009416 response to light stimulus 0.0305481371586169 328 105 7 0.0666666666666667 0.0213414634146341
GO:BP GO:0009165 nucleotide biosynthetic process 0.0307492876560551 269 128 7 0.0546875 0.0260223048327138
GO:BP GO:0051338 regulation of transferase activity 0.0307492876560551 1035 130 16 0.123076923076923 0.0154589371980676
GO:BP GO:0003018 vascular process in circulatory system 0.0310619453366033 256 101 6 0.0594059405940594 0.0234375
GO:BP GO:0043470 regulation of carbohydrate catabolic process 0.0311046660070625 90 59 3 0.0508474576271186 0.0333333333333333
GO:BP GO:1901699 cellular response to nitrogen compound 0.0311046660070625 724 105 11 0.104761904761905 0.0151933701657459
GO:BP GO:0006164 purine nucleotide biosynthetic process 0.0311046660070625 202 128 6 0.046875 0.0297029702970297
GO:BP GO:0045022 early endosome to late endosome transport 0.0311046660070625 39 137 3 0.0218978102189781 0.0769230769230769
GO:BP GO:0010466 negative regulation of peptidase activity 0.0311046660070625 267 97 6 0.0618556701030928 0.0224719101123595
GO:BP GO:1902743 regulation of lamellipodium organization 0.0311442344893864 55 97 3 0.0309278350515464 0.0545454545454545
GO:BP GO:0002064 epithelial cell development 0.0311442344893864 218 119 6 0.0504201680672269 0.0275229357798165
GO:BP GO:0006873 cellular ion homeostasis 0.0314197756482198 687 127 12 0.094488188976378 0.0174672489082969
GO:BP GO:0035337 fatty-acyl-CoA metabolic process 0.0314197756482198 42 128 3 0.0234375 0.0714285714285714
GO:BP GO:1901293 nucleoside phosphate biosynthetic process 0.0316988186533409 273 128 7 0.0546875 0.0256410256410256
GO:BP GO:0060113 inner ear receptor cell differentiation 0.0319545881553893 63 86 3 0.0348837209302326 0.0476190476190476
GO:BP GO:0022411 cellular component disassembly 0.0328629751571388 571 134 11 0.082089552238806 0.0192644483362522
GO:BP GO:0030855 epithelial cell differentiation 0.0333102065105043 798 97 11 0.11340206185567 0.0137844611528822
GO:BP GO:0042147 retrograde transport, endosome to Golgi 0.0333102065105043 92 123 4 0.032520325203252 0.0434782608695652
GO:BP GO:0018209 peptidyl-serine modification 0.0333710791049466 336 106 7 0.0660377358490566 0.0208333333333333
GO:BP GO:2000649 regulation of sodium ion transmembrane transporter activity 0.0338521952346214 53 106 3 0.0283018867924528 0.0566037735849057
GO:BP GO:0007167 enzyme linked receptor protein signaling pathway 0.0349064298207844 1103 103 14 0.135922330097087 0.0126926563916591
GO:BP GO:0010506 regulation of autophagy 0.0352444483558058 336 136 8 0.0588235294117647 0.0238095238095238
GO:BP GO:0048878 chemical homeostasis 0.0355597114074976 1229 113 16 0.141592920353982 0.0130187144019528
GO:BP GO:0048608 reproductive structure development 0.0356116138206161 429 85 7 0.0823529411764706 0.0163170163170163
GO:BP GO:0051494 negative regulation of cytoskeleton organization 0.0356116138206161 166 114 5 0.043859649122807 0.0301204819277108
GO:BP GO:0006979 response to oxidative stress 0.0356116138206161 466 99 8 0.0808080808080808 0.0171673819742489
GO:BP GO:0002224 toll-like receptor signaling pathway 0.0358099457617776 161 118 5 0.0423728813559322 0.031055900621118
GO:BP GO:0072522 purine-containing compound biosynthetic process 0.0358099457617776 213 128 6 0.046875 0.028169014084507
GO:BP GO:0003013 circulatory system process 0.0359977887188481 637 106 10 0.0943396226415094 0.0156985871271586
GO:BP GO:0061458 reproductive system development 0.0361361072201868 432 85 7 0.0823529411764706 0.0162037037037037
GO:BP GO:0030335 positive regulation of cell migration 0.0362348325585144 567 119 10 0.0840336134453782 0.017636684303351
GO:BP GO:0120032 regulation of plasma membrane bounded cell projection assembly 0.0374610677627613 190 102 5 0.0490196078431373 0.0263157894736842
GO:BP GO:1902904 negative regulation of supramolecular fiber organization 0.03746721350027 170 114 5 0.043859649122807 0.0294117647058824
GO:BP GO:0007029 endoplasmic reticulum organization 0.0380451268439642 87 139 4 0.0287769784172662 0.0459770114942529
GO:BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 0.0380451268439642 96 126 4 0.0317460317460317 0.0416666666666667
GO:BP GO:0006997 nucleus organization 0.0380451268439642 130 93 4 0.043010752688172 0.0307692307692308
GO:BP GO:0071417 cellular response to organonitrogen compound 0.0383264233129642 666 103 10 0.0970873786407767 0.015015015015015
GO:BP GO:0009887 animal organ morphogenesis 0.0383264233129642 1073 86 12 0.13953488372093 0.0111835973904939
GO:BP GO:0007602 phototransduction 0.0383264233129642 58 105 3 0.0285714285714286 0.0517241379310345
GO:BP GO:0030004 cellular monovalent inorganic cation homeostasis 0.0383264233129642 118 103 4 0.0388349514563107 0.0338983050847458
GO:BP GO:0070887 cellular response to chemical stimulus 0.0383264233129642 3393 109 32 0.293577981651376 0.00943118184497495
GO:BP GO:0060491 regulation of cell projection assembly 0.0383264233129642 192 102 5 0.0490196078431373 0.0260416666666667
GO:BP GO:0010038 response to metal ion 0.0383264233129642 371 127 8 0.062992125984252 0.0215633423180593
GO:BP GO:0045216 cell-cell junction organization 0.0385106835287675 216 130 6 0.0461538461538462 0.0277777777777778
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.0385106835287675 1227 105 15 0.142857142857143 0.0122249388753056
GO:BP GO:1903076 regulation of protein localization to plasma membrane 0.0389620853930008 105 117 4 0.0341880341880342 0.0380952380952381
GO:BP GO:0032233 positive regulation of actin filament bundle assembly 0.0390618010257993 64 97 3 0.0309278350515464 0.046875
GO:BP GO:0006749 glutathione metabolic process 0.0390618010257993 63 99 3 0.0303030303030303 0.0476190476190476
GO:BP GO:0001738 morphogenesis of a polarized epithelium 0.0390618010257993 152 130 5 0.0384615384615385 0.0328947368421053
GO:BP GO:0048699 generation of neurons 0.0390618010257993 1559 76 14 0.184210526315789 0.00898011545862733
GO:BP GO:0006644 phospholipid metabolic process 0.0390618010257993 427 136 9 0.0661764705882353 0.0210772833723653
GO:BP GO:0030182 neuron differentiation 0.0390618010257993 1412 119 18 0.151260504201681 0.0127478753541076
GO:BP GO:0042326 negative regulation of phosphorylation 0.0393932544127427 420 114 8 0.0701754385964912 0.019047619047619
GO:BP GO:0032412 regulation of ion transmembrane transporter activity 0.0395800491662254 270 106 6 0.0566037735849057 0.0222222222222222
GO:BP GO:0097061 dendritic spine organization 0.0396269577848502 83 76 3 0.0394736842105263 0.036144578313253
GO:BP GO:0016311 dephosphorylation 0.0401818796225782 508 95 8 0.0842105263157895 0.015748031496063
GO:BP GO:0006886 intracellular protein transport 0.0401818796225782 1186 131 17 0.129770992366412 0.0143338954468803
GO:BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 0.0401818796225782 100 126 4 0.0317460317460317 0.04
GO:BP GO:1903078 positive regulation of protein localization to plasma membrane 0.0410031451163357 63 102 3 0.0294117647058824 0.0476190476190476
GO:BP GO:0006869 lipid transport 0.0410903136917566 480 14 3 0.214285714285714 0.00625
GO:BP GO:0045859 regulation of protein kinase activity 0.0411668870060684 809 130 13 0.1 0.0160692212608158
GO:BP GO:0042752 regulation of circadian rhythm 0.0419322242424443 122 105 4 0.0380952380952381 0.0327868852459016
GO:BP GO:2000147 positive regulation of cell motility 0.042148064803814 591 119 10 0.0840336134453782 0.0169204737732657
GO:BP GO:0046847 filopodium assembly 0.0422758750549958 64 102 3 0.0294117647058824 0.046875
GO:BP GO:0006909 phagocytosis 0.0425113731750941 387 76 6 0.0789473684210526 0.0155038759689922
GO:BP GO:0030837 negative regulation of actin filament polymerization 0.042634867848505 68 97 3 0.0309278350515464 0.0441176470588235
GO:BP GO:0022600 digestive system process 0.042634867848505 102 127 4 0.031496062992126 0.0392156862745098
GO:BP GO:1900182 positive regulation of protein localization to nucleus 0.042634867848505 90 73 3 0.0410958904109589 0.0333333333333333
GO:BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 0.042634867848505 103 126 4 0.0317460317460317 0.0388349514563107
GO:BP GO:1902305 regulation of sodium ion transmembrane transport 0.0437523011107476 63 106 3 0.0283018867924528 0.0476190476190476
GO:BP GO:0022898 regulation of transmembrane transporter activity 0.0445263860616106 281 106 6 0.0566037735849057 0.0213523131672598
GO:BP GO:0072665 protein localization to vacuole 0.0445263860616106 71 95 3 0.0315789473684211 0.0422535211267606
GO:BP GO:0007612 learning 0.0451512105262894 146 91 4 0.043956043956044 0.0273972602739726
GO:BP GO:0022604 regulation of cell morphogenesis 0.0452622938661335 309 97 6 0.0618556701030928 0.0194174757281553
GO:BP GO:0055080 cation homeostasis 0.0458394446665714 750 127 12 0.094488188976378 0.016
GO:BP GO:0051272 positive regulation of cellular component movement 0.0459235212797004 604 119 10 0.0840336134453782 0.0165562913907285
GO:BP GO:0060429 epithelium development 0.0459618698854714 1325 130 18 0.138461538461538 0.0135849056603774
GO:BP GO:0040017 positive regulation of locomotion 0.0460624050803627 606 119 10 0.0840336134453782 0.0165016501650165
GO:BP GO:0035383 thioester metabolic process 0.0460624050803627 105 128 4 0.03125 0.0380952380952381
GO:BP GO:0006637 acyl-CoA metabolic process 0.0460624050803627 105 128 4 0.03125 0.0380952380952381
GO:BP GO:0120036 plasma membrane bounded cell projection organization 0.0460624050803627 1569 119 19 0.159663865546218 0.0121096239643085
GO:BP GO:0051270 regulation of cellular component movement 0.0460624050803627 1141 106 14 0.132075471698113 0.0122699386503067
GO:BP GO:1902003 regulation of amyloid-beta formation 0.0461141863854676 50 139 3 0.0215827338129496 0.06
GO:BP GO:0016197 endosomal transport 0.0462811194047294 246 123 6 0.0487804878048781 0.024390243902439
GO:BP GO:0007611 learning or memory 0.0464329000866358 257 118 6 0.0508474576271186 0.0233463035019455
GO:BP GO:1903828 negative regulation of cellular protein localization 0.0465625202972332 116 117 4 0.0341880341880342 0.0344827586206897
GO:BP GO:0046165 alcohol biosynthetic process 0.0466065829458338 158 136 5 0.0367647058823529 0.0316455696202532
GO:BP GO:0006928 movement of cell or subcellular component 0.046976753101422 2311 106 23 0.216981132075472 0.0099524015577672
GO:BP GO:0018210 peptidyl-threonine modification 0.0471087891187392 129 106 4 0.0377358490566038 0.0310077519379845
GO:BP GO:0010876 lipid localization 0.0479638578709256 530 14 3 0.214285714285714 0.00566037735849057
GO:BP GO:0051246 regulation of protein metabolic process 0.0484481657843401 2704 139 32 0.23021582733813 0.0118343195266272
GO:BP GO:1904377 positive regulation of protein localization to cell periphery 0.0484481657843401 70 102 3 0.0294117647058824 0.0428571428571429
GO:BP GO:1902652 secondary alcohol metabolic process 0.0484627290229124 164 133 5 0.037593984962406 0.0304878048780488
GO:BP GO:0043624 cellular protein complex disassembly 0.0487791859440309 226 97 5 0.0515463917525773 0.0221238938053097
GO:BP GO:0043413 macromolecule glycosylation 0.0487791859440309 251 29 3 0.103448275862069 0.0119521912350598
GO:BP GO:0006486 protein glycosylation 0.0487791859440309 251 29 3 0.103448275862069 0.0119521912350598
GO:BP GO:0010632 regulation of epithelial cell migration 0.0492487390250712 306 102 6 0.0588235294117647 0.0196078431372549
GO:BP GO:0019216 regulation of lipid metabolic process 0.0492487390250712 419 18 3 0.166666666666667 0.00715990453460621
GO:BP GO:0040014 regulation of multicellular organism growth 0.0492487390250712 65 113 3 0.0265486725663717 0.0461538461538462
GO:BP GO:0048667 cell morphogenesis involved in neuron differentiation 0.0492487390250712 602 86 8 0.0930232558139535 0.0132890365448505
GO:BP GO:0034599 cellular response to oxidative stress 0.0492487390250712 316 99 6 0.0606060606060606 0.0189873417721519
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.0492487390250712 1042 130 15 0.115384615384615 0.0143953934740883
GO:BP GO:0030003 cellular cation homeostasis 0.0492487390250712 673 127 11 0.0866141732283465 0.0163447251114413
GO:BP GO:0061919 process utilizing autophagic mechanism 0.049407381713666 543 136 10 0.0735294117647059 0.0184162062615101
GO:BP GO:0006914 autophagy 0.049407381713666 543 136 10 0.0735294117647059 0.0184162062615101
GO:BP GO:1903350 response to dopamine 0.049615870484816 87 86 3 0.0348837209302326 0.0344827586206897
GO:BP GO:1901700 response to oxygen-containing compound 0.049615870484816 1739 110 19 0.172727272727273 0.0109258194364577
GO:BP GO:0090596 sensory organ morphogenesis 0.049615870484816 262 86 5 0.0581395348837209 0.0190839694656489
GO:BP GO:0071674 mononuclear cell migration 0.049615870484816 191 75 4 0.0533333333333333 0.0209424083769634
GO:BP GO:1903351 cellular response to dopamine 0.049615870484816 86 86 3 0.0348837209302326 0.0348837209302326
GO:BP GO:0031333 negative regulation of protein-containing complex assembly 0.049615870484816 147 97 4 0.0412371134020619 0.0272108843537415
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.049615870484816 1082 114 14 0.12280701754386 0.0129390018484288
GO:BP GO:0032409 regulation of transporter activity 0.049615870484816 297 106 6 0.0566037735849057 0.0202020202020202
GO:BP GO:0032872 regulation of stress-activated MAPK cascade 0.049615870484816 190 118 5 0.0423728813559322 0.0263157894736842
GO:BP GO:0007163 establishment or maintenance of cell polarity 0.049615870484816 220 102 5 0.0490196078431373 0.0227272727272727
GO:BP GO:0006066 alcohol metabolic process 0.049615870484816 382 136 8 0.0588235294117647 0.0209424083769634
GO:BP GO:0000902 cell morphogenesis 0.049615870484816 1037 119 14 0.117647058823529 0.0135004821600771
GO:BP GO:0060071 Wnt signaling pathway, planar cell polarity pathway 0.049615870484816 110 130 4 0.0307692307692308 0.0363636363636364
GO:BP GO:0046031 ADP metabolic process 0.049615870484816 123 61 3 0.0491803278688525 0.024390243902439
GO:CC GO:0070062 extracellular exosome 4.23845908622518e-10 2176 131 46 0.351145038167939 0.0211397058823529
GO:CC GO:0043230 extracellular organelle 5.68732943261151e-10 2263 131 46 0.351145038167939 0.0203269995581087
GO:CC GO:1903561 extracellular vesicle 5.68732943261151e-10 2261 131 46 0.351145038167939 0.0203449800973021
GO:CC GO:0005737 cytoplasm 7.55882984822027e-09 11911 137 120 0.875912408759124 0.0100747208462766
GO:CC GO:0031982 vesicle 3.0155183232375e-08 4055 134 61 0.455223880597015 0.0150431565967941
GO:CC GO:0098588 bounding membrane of organelle 1.25763760789416e-06 2158 139 40 0.287769784172662 0.0185356811862836
GO:CC GO:0015629 actin cytoskeleton 2.20997450961627e-06 513 123 17 0.138211382113821 0.0331384015594542
GO:CC GO:0031090 organelle membrane 2.84581812191016e-06 3612 140 54 0.385714285714286 0.0149501661129568
GO:CC GO:0005925 focal adhesion 2.84581812191016e-06 420 119 15 0.126050420168067 0.0357142857142857
GO:CC GO:0030055 cell-substrate junction 3.17755850999569e-06 427 119 15 0.126050420168067 0.0351288056206089
GO:CC GO:0012505 endomembrane system 2.81774639945782e-05 4640 132 58 0.439393939393939 0.0125
GO:CC GO:0070161 anchoring junction 3.73694028506936e-05 836 130 20 0.153846153846154 0.0239234449760766
GO:CC GO:0005615 extracellular space 4.1875119759209e-05 3594 105 41 0.39047619047619 0.0114079020589872
GO:CC GO:0005794 Golgi apparatus 4.76275848984875e-05 1623 131 29 0.221374045801527 0.0178681454097351
GO:CC GO:0005856 cytoskeleton 6.67162859325709e-05 2332 137 37 0.27007299270073 0.0158662092624357
GO:CC GO:0098858 actin-based cell projection 7.93777001085395e-05 220 103 9 0.087378640776699 0.0409090909090909
GO:CC GO:0043226 organelle 7.93777001085395e-05 14008 137 123 0.897810218978102 0.0087806967447173
GO:CC GO:0005829 cytosol 0.000102503558185084 5303 107 52 0.485981308411215 0.00980577031868753
GO:CC GO:0043229 intracellular organelle 0.000102503558185084 12491 137 114 0.832116788321168 0.00912657113121448
GO:CC GO:0043227 membrane-bounded organelle 0.000142855499495008 12858 136 115 0.845588235294118 0.00894384818789858
GO:CC GO:0016020 membrane 0.00018746053702086 9838 140 98 0.7 0.0099613742630616
GO:CC GO:0009898 cytoplasmic side of plasma membrane 0.000212472744898869 168 119 8 0.0672268907563025 0.0476190476190476
GO:CC GO:0031252 cell leading edge 0.000260171553597262 422 119 12 0.100840336134454 0.028436018957346
GO:CC GO:0005903 brush border 0.000325250828801203 107 97 6 0.0618556701030928 0.0560747663551402
GO:CC GO:0031984 organelle subcompartment 0.000500479640171687 1773 139 29 0.20863309352518 0.0163564579808235
GO:CC GO:0098562 cytoplasmic side of membrane 0.000508132874157696 194 119 8 0.0672268907563025 0.0412371134020619
GO:CC GO:0005622 intracellular anatomical structure 0.000519456761759682 14790 137 125 0.912408759124088 0.00845165652467884
GO:CC GO:0005783 endoplasmic reticulum 0.000531856259406569 1982 139 31 0.223021582733813 0.0156407669021191
GO:CC GO:0005576 extracellular region 0.00060796407214316 4567 105 44 0.419047619047619 0.00963433326034596
GO:CC GO:0005773 vacuole 0.000906437551329438 810 135 17 0.125925925925926 0.0209876543209877
GO:CC GO:0032432 actin filament bundle 0.00131567805111388 76 115 5 0.0434782608695652 0.0657894736842105
GO:CC GO:0005777 peroxisome 0.0016246781924539 141 107 6 0.0560747663551402 0.0425531914893617
GO:CC GO:0005902 microvillus 0.0016246781924539 91 103 5 0.0485436893203883 0.0549450549450549
GO:CC GO:0042579 microbody 0.0016246781924539 141 107 6 0.0560747663551402 0.0425531914893617
GO:CC GO:0005768 endosome 0.0016246781924539 987 130 18 0.138461538461538 0.0182370820668693
GO:CC GO:0071944 cell periphery 0.0016246781924539 6169 106 53 0.5 0.00859134381585346
GO:CC GO:0005886 plasma membrane 0.0016246781924539 5681 119 55 0.46218487394958 0.00968139412075339
GO:CC GO:0000323 lytic vacuole 0.00176485201071452 712 135 15 0.111111111111111 0.0210674157303371
GO:CC GO:0005764 lysosome 0.00176485201071452 712 135 15 0.111111111111111 0.0210674157303371
GO:CC GO:0030054 cell junction 0.00180347533723594 2105 130 29 0.223076923076923 0.0137767220902613
GO:CC GO:0098862 cluster of actin-based cell projections 0.00183274263406628 162 97 6 0.0618556701030928 0.037037037037037
GO:CC GO:0005769 early endosome 0.00196698582527689 378 102 9 0.0882352941176471 0.0238095238095238
GO:CC GO:0031907 microbody lumen 0.00209045616486762 53 107 4 0.0373831775700935 0.0754716981132075
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.00209045616486762 11296 136 101 0.742647058823529 0.00894121813031161
GO:CC GO:0005782 peroxisomal matrix 0.00209045616486762 53 107 4 0.0373831775700935 0.0754716981132075
GO:CC GO:0030139 endocytic vesicle 0.00225435256793581 306 130 9 0.0692307692307692 0.0294117647058824
GO:CC GO:0098791 Golgi apparatus subcompartment 0.00225435256793581 885 139 17 0.122302158273381 0.0192090395480226
GO:CC GO:0030175 filopodium 0.00234230239434777 107 102 5 0.0490196078431373 0.0467289719626168
GO:CC GO:0030864 cortical actin cytoskeleton 0.00234230239434777 79 76 4 0.0526315789473684 0.0506329113924051
GO:CC GO:0042995 cell projection 0.00304193230949401 2330 106 26 0.245283018867925 0.0111587982832618
GO:CC GO:0005778 peroxisomal membrane 0.00358035882437617 64 107 4 0.0373831775700935 0.0625
GO:CC GO:0031234 extrinsic component of cytoplasmic side of plasma membrane 0.00358035882437617 102 119 5 0.0420168067226891 0.0490196078431373
GO:CC GO:0031903 microbody membrane 0.00358035882437617 64 107 4 0.0373831775700935 0.0625
GO:CC GO:0098552 side of membrane 0.00389158700454081 619 119 12 0.100840336134454 0.0193861066235864
GO:CC GO:0000139 Golgi membrane 0.003987652527727 771 139 15 0.107913669064748 0.0194552529182879
GO:CC GO:0005938 cell cortex 0.00449066742405708 311 115 8 0.0695652173913043 0.0257234726688103
GO:CC GO:0010008 endosome membrane 0.00504743333580557 505 130 11 0.0846153846153846 0.0217821782178218
GO:CC GO:0030125 clathrin vesicle coat 0.00572604889856989 28 126 3 0.0238095238095238 0.107142857142857
GO:CC GO:0019897 extrinsic component of plasma membrane 0.00581234131944411 176 119 6 0.0504201680672269 0.0340909090909091
GO:CC GO:0030863 cortical cytoskeleton 0.00600667818661523 107 76 4 0.0526315789473684 0.0373831775700935
GO:CC GO:0001726 ruffle 0.00614980727507452 179 119 6 0.0504201680672269 0.0335195530726257
GO:CC GO:0120025 plasma membrane bounded cell projection 0.00719304606928112 2229 106 24 0.226415094339623 0.0107671601615074
GO:CC GO:0030665 clathrin-coated vesicle membrane 0.00722571430182321 114 130 5 0.0384615384615385 0.043859649122807
GO:CC GO:0005774 vacuolar membrane 0.00780318637309378 441 135 10 0.0740740740740741 0.0226757369614512
GO:CC GO:0005789 endoplasmic reticulum membrane 0.00842043060588762 1117 139 18 0.129496402877698 0.0161145926589078
GO:CC GO:0098827 endoplasmic reticulum subcompartment 0.00872423655544439 1122 139 18 0.129496402877698 0.0160427807486631
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 0.00998023665100039 1139 139 18 0.129496402877698 0.0158033362598771
GO:CC GO:0005765 lysosomal membrane 0.00998023665100039 383 135 9 0.0666666666666667 0.0234986945169713
GO:CC GO:0098852 lytic vacuole membrane 0.00998023665100039 383 135 9 0.0666666666666667 0.0234986945169713
GO:CC GO:1904813 ficolin-1-rich granule lumen 0.0103505769737672 124 79 4 0.0506329113924051 0.032258064516129
GO:CC GO:0030669 clathrin-coated endocytic vesicle membrane 0.0108521629964442 36 130 3 0.0230769230769231 0.0833333333333333
GO:CC GO:0032420 stereocilium 0.0112023462438565 55 86 3 0.0348837209302326 0.0545454545454545
GO:CC GO:0032421 stereocilium bundle 0.0151857952438074 62 86 3 0.0348837209302326 0.0483870967741935
GO:CC GO:0031410 cytoplasmic vesicle 0.0152863897158073 2424 134 29 0.216417910447761 0.011963696369637
GO:CC GO:0097708 intracellular vesicle 0.0153632343831892 2428 134 29 0.216417910447761 0.0119439868204283
GO:CC GO:0098794 postsynapse 0.0184181660264062 639 126 11 0.0873015873015873 0.0172143974960876
GO:CC GO:0030027 lamellipodium 0.0185803016069986 200 97 5 0.0515463917525773 0.025
GO:CC GO:0030118 clathrin coat 0.0188602533979324 47 126 3 0.0238095238095238 0.0638297872340425
GO:CC GO:0043005 neuron projection 0.0200313807679743 1380 106 16 0.150943396226415 0.0115942028985507
GO:CC GO:0005739 mitochondrion 0.0219982602789279 1673 113 19 0.168141592920354 0.0113568439928273
GO:CC GO:0030666 endocytic vesicle membrane 0.0225688252018949 159 130 5 0.0384615384615385 0.0314465408805031
GO:CC GO:0098590 plasma membrane region 0.0254722413850081 1240 132 17 0.128787878787879 0.0137096774193548
GO:CC GO:0030120 vesicle coat 0.026272143519896 55 126 3 0.0238095238095238 0.0545454545454545
GO:CC GO:0048471 perinuclear region of cytoplasm 0.0264274780639957 735 134 12 0.0895522388059701 0.0163265306122449
GO:CC GO:0045334 clathrin-coated endocytic vesicle 0.0266532169616552 54 130 3 0.0230769230769231 0.0555555555555556
GO:CC GO:0005911 cell-cell junction 0.0274453439171843 494 84 7 0.0833333333333333 0.01417004048583
GO:CC GO:0005759 mitochondrial matrix 0.0286245865856466 479 133 9 0.0676691729323308 0.0187891440501044
GO:CC GO:0099572 postsynaptic specialization 0.0300919942043129 358 118 7 0.0593220338983051 0.0195530726256983
GO:CC GO:0101002 ficolin-1-rich granule 0.0303038647518734 184 79 4 0.0506329113924051 0.0217391304347826
GO:CC GO:0030662 coated vesicle membrane 0.0305427617954414 177 130 5 0.0384615384615385 0.0282485875706215
GO:CC GO:0030496 midbody 0.0313458284004922 196 119 5 0.0420168067226891 0.0255102040816327
GO:CC GO:0016323 basolateral plasma membrane 0.0313458284004922 222 35 3 0.0857142857142857 0.0135135135135135
GO:CC GO:0045177 apical part of cell 0.0351389374843615 431 103 7 0.0679611650485437 0.0162412993039443
GO:CC GO:0031985 Golgi cisterna 0.0361604587648757 115 72 3 0.0416666666666667 0.0260869565217391
GO:CC GO:0044853 plasma membrane raft 0.0376914243600614 116 73 3 0.0410958904109589 0.0258620689655172
GO:CC GO:0009925 basal plasma membrane 0.038045758645441 247 35 3 0.0857142857142857 0.0121457489878543
GO:CC GO:0030136 clathrin-coated vesicle 0.0382966057950038 193 130 5 0.0384615384615385 0.0259067357512953
GO:CC GO:0005905 clathrin-coated pit 0.0405978725577709 71 126 3 0.0238095238095238 0.0422535211267606
GO:CC GO:0045178 basal part of cell 0.0430566367796559 265 35 3 0.0857142857142857 0.0113207547169811
GO:CC GO:0015630 microtubule cytoskeleton 0.0444139070363501 1307 137 17 0.124087591240876 0.0130068859984698
GO:CC GO:0019898 extrinsic component of membrane 0.046474991826682 313 119 6 0.0504201680672269 0.0191693290734824
GO:CC GO:0043025 neuronal cell body 0.0472869249958351 518 94 7 0.074468085106383 0.0135135135135135
GO:MF GO:1901265 nucleoside phosphate binding 3.07209482543944e-05 2172 113 34 0.300884955752212 0.0156537753222836
GO:MF GO:0000166 nucleotide binding 3.07209482543944e-05 2171 113 34 0.300884955752212 0.015660985720866
GO:MF GO:0045296 cadherin binding 4.39176111088279e-05 333 82 11 0.134146341463415 0.033033033033033
GO:MF GO:0050839 cell adhesion molecule binding 0.000103087003850492 546 82 13 0.158536585365854 0.0238095238095238
GO:MF GO:0043168 anion binding 0.00027983159563288 2418 122 35 0.286885245901639 0.0144747725392887
GO:MF GO:0036094 small molecule binding 0.00027983159563288 2506 113 34 0.300884955752212 0.0135674381484437
GO:MF GO:0097367 carbohydrate derivative binding 0.00027983159563288 2285 113 32 0.283185840707965 0.0140043763676149
GO:MF GO:0008092 cytoskeletal protein binding 0.000340594957274081 996 119 20 0.168067226890756 0.0200803212851406
GO:MF GO:0017076 purine nucleotide binding 0.000440109630280931 1933 113 28 0.247787610619469 0.0144852560786342
GO:MF GO:0032555 purine ribonucleotide binding 0.000440109630280931 1918 113 28 0.247787610619469 0.0145985401459854
GO:MF GO:0051015 actin filament binding 0.000440109630280931 212 119 9 0.0756302521008403 0.0424528301886792
GO:MF GO:0032553 ribonucleotide binding 0.000440109630280931 1935 113 28 0.247787610619469 0.0144702842377261
GO:MF GO:0004857 enzyme inhibitor activity 0.00107105789897411 385 135 12 0.0888888888888889 0.0311688311688312
GO:MF GO:0003779 actin binding 0.00111405856919915 448 137 13 0.0948905109489051 0.0290178571428571
GO:MF GO:0035639 purine ribonucleoside triphosphate binding 0.0012925133379496 1847 113 26 0.230088495575221 0.0140768814293449
GO:MF GO:0032559 adenyl ribonucleotide binding 0.00186019975649259 1565 113 23 0.20353982300885 0.0146964856230032
GO:MF GO:0030554 adenyl nucleotide binding 0.00199566551622664 1578 113 23 0.20353982300885 0.014575411913815
GO:MF GO:0019900 kinase binding 0.00206970104511859 752 130 16 0.123076923076923 0.0212765957446809
GO:MF GO:0019901 protein kinase binding 0.00206970104511859 673 130 15 0.115384615384615 0.0222882615156018
GO:MF GO:0004869 cysteine-type endopeptidase inhibitor activity 0.00377183812499756 52 97 4 0.0412371134020619 0.0769230769230769
GO:MF GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 0.00399669650490881 21 97 3 0.0309278350515464 0.142857142857143
GO:MF GO:0003824 catalytic activity 0.0050909637420047 5896 113 54 0.47787610619469 0.00915875169606513
GO:MF GO:0005524 ATP binding 0.00518580902612215 1501 113 21 0.185840707964602 0.0139906728847435
GO:MF GO:0048306 calcium-dependent protein binding 0.00947285546252296 82 35 3 0.0857142857142857 0.0365853658536585
GO:MF GO:0019899 enzyme binding 0.0100795726904037 2074 132 28 0.212121212121212 0.0135004821600771
GO:MF GO:0044877 protein-containing complex binding 0.0102553765134243 1287 130 20 0.153846153846154 0.0155400155400155
GO:MF GO:0004860 protein kinase inhibitor activity 0.0116783713406505 70 47 3 0.0638297872340425 0.0428571428571429
GO:MF GO:0019210 kinase inhibitor activity 0.0126441364118422 74 47 3 0.0638297872340425 0.0405405405405405
GO:MF GO:0042802 identical protein binding 0.0134626255035258 2067 137 28 0.204379562043796 0.0135462022254475
GO:MF GO:1901981 phosphatidylinositol phosphate binding 0.0134626255035258 172 122 6 0.0491803278688525 0.0348837209302326
GO:MF GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 0.0138256475690764 38 97 3 0.0309278350515464 0.0789473684210526
GO:MF GO:0016836 hydro-lyase activity 0.0156457128482853 65 133 4 0.0300751879699248 0.0615384615384615
GO:MF GO:0098632 cell-cell adhesion mediator activity 0.0156990313709388 49 82 3 0.0365853658536585 0.0612244897959184
GO:MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.0156990313709388 125 120 5 0.0416666666666667 0.04
GO:MF GO:0030276 clathrin binding 0.0156990313709388 70 126 4 0.0317460317460317 0.0571428571428571
GO:MF GO:0019887 protein kinase regulator activity 0.0167070932899292 191 119 6 0.0504201680672269 0.031413612565445
GO:MF GO:0035091 phosphatidylinositol binding 0.0167196456879356 255 122 7 0.0573770491803279 0.0274509803921569
GO:MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 0.0182460270901393 137 120 5 0.0416666666666667 0.0364963503649635
GO:MF GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 0.0182460270901393 39 122 3 0.0245901639344262 0.0769230769230769
GO:MF GO:0098631 cell adhesion mediator activity 0.0182460270901393 58 82 3 0.0365853658536585 0.0517241379310345
GO:MF GO:0042803 protein homodimerization activity 0.0182460270901393 676 107 11 0.102803738317757 0.0162721893491124
GO:MF GO:0004866 endopeptidase inhibitor activity 0.0182460270901393 176 97 5 0.0515463917525773 0.0284090909090909
GO:MF GO:0000287 magnesium ion binding 0.0184552935293391 222 78 5 0.0641025641025641 0.0225225225225225
GO:MF GO:0030414 peptidase inhibitor activity 0.0197446930358703 182 97 5 0.0515463917525773 0.0274725274725275
GO:MF GO:0016835 carbon-oxygen lyase activity 0.019752102152428 81 133 4 0.0300751879699248 0.0493827160493827
GO:MF GO:0050661 NADP binding 0.019752102152428 52 99 3 0.0303030303030303 0.0576923076923077
GO:MF GO:0043167 ion binding 0.019752102152428 6057 136 60 0.441176470588235 0.00990589400693413
GO:MF GO:0061135 endopeptidase regulator activity 0.0203550015522346 188 97 5 0.0515463917525773 0.0265957446808511
GO:MF GO:0005543 phospholipid binding 0.0203550015522346 454 122 9 0.0737704918032787 0.0198237885462555
GO:MF GO:0019207 kinase regulator activity 0.0203550015522346 221 119 6 0.0504201680672269 0.0271493212669683
GO:MF GO:0030234 enzyme regulator activity 0.0212071722761595 1248 123 17 0.138211382113821 0.0136217948717949
GO:MF GO:0005509 calcium ion binding 0.0212071722761595 721 27 5 0.185185185185185 0.00693481276005548
GO:MF GO:0008509 anion transmembrane transporter activity 0.0216616270220906 464 42 5 0.119047619047619 0.0107758620689655
GO:MF GO:0051287 NAD binding 0.0234803233303982 55 110 3 0.0272727272727273 0.0545454545454545
GO:MF GO:0008514 organic anion transmembrane transporter activity 0.0252029785512348 187 111 5 0.045045045045045 0.0267379679144385
GO:MF GO:0005525 GTP binding 0.025743712973678 381 131 8 0.0610687022900763 0.020997375328084
GO:MF GO:0032550 purine ribonucleoside binding 0.0273094222119711 386 131 8 0.0610687022900763 0.0207253886010363
GO:MF GO:0061134 peptidase regulator activity 0.0274688792220992 224 97 5 0.0515463917525773 0.0223214285714286
GO:MF GO:0001883 purine nucleoside binding 0.0274688792220992 389 131 8 0.0610687022900763 0.0205655526992288
GO:MF GO:0032549 ribonucleoside binding 0.0274688792220992 389 131 8 0.0610687022900763 0.0205655526992288
GO:MF GO:0017111 nucleoside-triphosphatase activity 0.0281824588917888 872 113 12 0.106194690265487 0.0137614678899083
GO:MF GO:0001882 nucleoside binding 0.0285971818884284 395 131 8 0.0610687022900763 0.020253164556962
GO:MF GO:0016791 phosphatase activity 0.0300872608203531 289 78 5 0.0641025641025641 0.0173010380622837
GO:MF GO:0044325 ion channel binding 0.030424805042181 135 106 4 0.0377358490566038 0.0296296296296296
GO:MF GO:0019001 guanyl nucleotide binding 0.0305750139101271 403 131 8 0.0610687022900763 0.0198511166253102
GO:MF GO:0032561 guanyl ribonucleotide binding 0.0305750139101271 403 131 8 0.0610687022900763 0.0198511166253102
GO:MF GO:0015932 nucleobase-containing compound transmembrane transporter activity 0.0307436835197229 68 111 3 0.027027027027027 0.0441176470588235
GO:MF GO:0030165 PDZ domain binding 0.0317800762433502 89 86 3 0.0348837209302326 0.0337078651685393
GO:MF GO:0016491 oxidoreductase activity 0.0337042454868008 771 11 3 0.272727272727273 0.00389105058365759
GO:MF GO:1901505 carbohydrate derivative transmembrane transporter activity 0.0337042454868008 72 111 3 0.027027027027027 0.0416666666666667
GO:MF GO:0005516 calmodulin binding 0.0351896492376808 204 119 5 0.0420168067226891 0.0245098039215686
GO:MF GO:0016247 channel regulator activity 0.0355647741242026 149 106 4 0.0377358490566038 0.0268456375838926
GO:MF GO:0016817 hydrolase activity, acting on acid anhydrides 0.0355647741242026 930 113 12 0.106194690265487 0.0129032258064516
GO:MF GO:0016462 pyrophosphatase activity 0.0355647741242026 928 113 12 0.106194690265487 0.0129310344827586
GO:MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0355647741242026 930 113 12 0.106194690265487 0.0129032258064516
GO:MF GO:0035591 signaling adaptor activity 0.0355647741242026 70 119 3 0.0252100840336134 0.0428571428571429
GO:MF GO:0005200 structural constituent of cytoskeleton 0.0381098265086936 104 84 3 0.0357142857142857 0.0288461538461538
GO:MF GO:0022853 active ion transmembrane transporter activity 0.038964570767168 213 42 3 0.0714285714285714 0.0140845070422535
GO:MF GO:1901363 heterocyclic compound binding 0.0393314529387698 6228 73 34 0.465753424657534 0.0054592164418754
GO:MF GO:1901681 sulfur compound binding 0.0393314529387698 264 64 4 0.0625 0.0151515151515152
GO:MF GO:0016301 kinase activity 0.0445807185622113 796 106 10 0.0943396226415094 0.0125628140703518
GO:MF GO:0097159 organic cyclic compound binding 0.0452118521546789 6309 73 34 0.465753424657534 0.00538912664447615
GO:MF GO:0005215 transporter activity 0.0452118521546789 1185 42 7 0.166666666666667 0.00590717299578059
GO:MF GO:0015291 secondary active transmembrane transporter activity 0.0460419881108176 237 42 3 0.0714285714285714 0.0126582278481013
GO:MF GO:0016773 phosphotransferase activity, alcohol group as acceptor 0.0474581082850519 692 106 9 0.0849056603773585 0.0130057803468208
HPA HPA:0400053 rectum; glandular cells[High] 0.00205500073395903 2687 97 44 0.45360824742268 0.0163751395608485
HPA HPA:0160053 endometrium 1; glandular cells[High] 0.00205500073395903 1413 138 38 0.27536231884058 0.02689313517339
HPA HPA:0030053 appendix; glandular cells[High] 0.00420214741625627 1986 82 31 0.378048780487805 0.0156092648539778
HPA HPA:0170053 endometrium 2; glandular cells[High] 0.0152025522451359 1282 27 11 0.407407407407407 0.00858034321372855
HPA HPA:0130053 colon; glandular cells[High] 0.0168320896056113 2538 26 15 0.576923076923077 0.00591016548463357
HPA HPA:0030052 appendix; glandular cells[≥Medium] 0.0284602921837479 5767 119 82 0.689075630252101 0.0142188312814288
HPA HPA:0150053 duodenum; glandular cells[High] 0.0284602921837479 2767 14 10 0.714285714285714 0.00361402240693892
HPA HPA:0610833 urinary bladder; urothelial cells[High] 0.0327814990054741 1969 116 36 0.310344827586207 0.0182833925850686
HPA HPA:0180053 epididymis; glandular cells[High] 0.046089774551926 1779 94 28 0.297872340425532 0.0157391793142215
KEGG KEGG:00920 Sulfur metabolism 0.0018848137765491 10 43 3 0.0697674418604651 0.3
KEGG KEGG:00020 Citrate cycle (TCA cycle) 0.0018848137765491 30 140 6 0.0428571428571429 0.2
KEGG KEGG:04520 Adherens junction 0.00455146759382641 71 119 7 0.0588235294117647 0.0985915492957746
KEGG KEGG:05135 Yersinia infection 0.00455146759382641 136 105 9 0.0857142857142857 0.0661764705882353
KEGG KEGG:01210 2-Oxocarboxylic acid metabolism 0.0090375354223619 19 133 4 0.0300751879699248 0.210526315789474
KEGG KEGG:04720 Long-term potentiation 0.0090375354223619 67 106 6 0.0566037735849057 0.0895522388059701
KEGG KEGG:05216 Thyroid cancer 0.0131129525517384 37 77 4 0.051948051948052 0.108108108108108
KEGG KEGG:04144 Endocytosis 0.023320256930167 252 131 12 0.0916030534351145 0.0476190476190476
KEGG KEGG:04912 GnRH signaling pathway 0.0348718292210156 93 106 6 0.0566037735849057 0.0645161290322581
MIRNA MIRNA:hsa-miR-1-3p hsa-miR-1-3p 3.24495577662871e-05 915 138 28 0.202898550724638 0.0306010928961749
MIRNA MIRNA:hsa-miR-3074-3p hsa-miR-3074-3p 0.0065734962777659 59 119 6 0.0504201680672269 0.101694915254237
MIRNA MIRNA:hsa-miR-142-5p hsa-miR-142-5p 0.0103624678285914 225 98 9 0.0918367346938776 0.04
MIRNA MIRNA:hsa-miR-224-5p hsa-miR-224-5p 0.014212993864757 132 101 7 0.0693069306930693 0.053030303030303
MIRNA MIRNA:hsa-miR-877-3p hsa-miR-877-3p 0.0167053683492718 602 3 3 1 0.00498338870431894
MIRNA MIRNA:hsa-miR-30c-5p hsa-miR-30c-5p 0.0167053683492718 519 131 15 0.114503816793893 0.0289017341040462
MIRNA MIRNA:hsa-miR-365a-3p hsa-miR-365a-3p 0.0167053683492718 123 82 6 0.0731707317073171 0.0487804878048781
MIRNA MIRNA:hsa-miR-5590-3p hsa-miR-5590-3p 0.0175181583242015 212 98 8 0.0816326530612245 0.0377358490566038
MIRNA MIRNA:hsa-miR-4799-5p hsa-miR-4799-5p 0.0227225218788771 93 122 6 0.0491803278688525 0.0645161290322581
MIRNA MIRNA:hsa-miR-3185 hsa-miR-3185 0.0230797737020635 164 102 7 0.0686274509803922 0.0426829268292683
MIRNA MIRNA:hsa-miR-9-3p hsa-miR-9-3p 0.0230797737020635 102 73 5 0.0684931506849315 0.0490196078431373
MIRNA MIRNA:hsa-miR-124-3p hsa-miR-124-3p 0.0239469478255423 1442 45 13 0.288888888888889 0.00901525658807212
MIRNA MIRNA:hsa-miR-155-5p hsa-miR-155-5p 0.0239469478255423 900 117 18 0.153846153846154 0.02
MIRNA MIRNA:hsa-miR-4282 hsa-miR-4282 0.0239469478255423 291 82 8 0.0975609756097561 0.0274914089347079
MIRNA MIRNA:hsa-miR-585-3p hsa-miR-585-3p 0.0239469478255423 19 89 3 0.0337078651685393 0.157894736842105
MIRNA MIRNA:hsa-miR-382-5p hsa-miR-382-5p 0.0239469478255423 109 117 6 0.0512820512820513 0.055045871559633
MIRNA MIRNA:hsa-miR-129-5p hsa-miR-129-5p 0.0239469478255423 621 136 16 0.117647058823529 0.0257648953301127
MIRNA MIRNA:hsa-miR-144-3p hsa-miR-144-3p 0.0271178630655205 207 25 4 0.16 0.0193236714975845
MIRNA MIRNA:hsa-miR-646 hsa-miR-646 0.0271178630655205 251 76 7 0.0921052631578947 0.0278884462151394
MIRNA MIRNA:hsa-miR-7111-3p hsa-miR-7111-3p 0.0271178630655205 217 117 8 0.0683760683760684 0.0368663594470046
MIRNA MIRNA:hsa-miR-8076 hsa-miR-8076 0.0271178630655205 79 115 5 0.0434782608695652 0.0632911392405063
MIRNA MIRNA:hsa-miR-636 hsa-miR-636 0.0271178630655205 100 49 4 0.0816326530612245 0.04
MIRNA MIRNA:hsa-miR-320a hsa-miR-320a 0.0305182228331726 584 85 11 0.129411764705882 0.0188356164383562
MIRNA MIRNA:hsa-miR-6865-3p hsa-miR-6865-3p 0.0305182228331726 105 22 3 0.136363636363636 0.0285714285714286
MIRNA MIRNA:hsa-miR-145-5p hsa-miR-145-5p 0.0305182228331726 237 114 8 0.0701754385964912 0.0337552742616034
MIRNA MIRNA:hsa-miR-3668 hsa-miR-3668 0.0305182228331726 70 77 4 0.051948051948052 0.0571428571428571
MIRNA MIRNA:hsa-miR-6864-3p hsa-miR-6864-3p 0.0331624361432482 320 136 10 0.0735294117647059 0.03125
MIRNA MIRNA:hsa-miR-3646 hsa-miR-3646 0.0331624361432482 198 112 7 0.0625 0.0353535353535354
MIRNA MIRNA:hsa-miR-5093 hsa-miR-5093 0.0331624361432482 118 84 5 0.0595238095238095 0.0423728813559322
MIRNA MIRNA:hsa-miR-8055 hsa-miR-8055 0.0331624361432482 317 136 10 0.0735294117647059 0.0315457413249211
MIRNA MIRNA:hsa-miR-6079 hsa-miR-6079 0.0331624361432482 128 47 4 0.0851063829787234 0.03125
MIRNA MIRNA:hsa-miR-497-3p hsa-miR-497-3p 0.0331624361432482 99 59 4 0.0677966101694915 0.0404040404040404
MIRNA MIRNA:hsa-miR-5683 hsa-miR-5683 0.0331624361432482 97 109 5 0.0458715596330275 0.0515463917525773
MIRNA MIRNA:hsa-miR-3672 hsa-miR-3672 0.0331624361432482 320 136 10 0.0735294117647059 0.03125
MIRNA MIRNA:hsa-miR-548at-5p hsa-miR-548at-5p 0.0331624361432482 122 85 5 0.0588235294117647 0.040983606557377
MIRNA MIRNA:hsa-miR-769-5p hsa-miR-769-5p 0.0331624361432482 228 27 4 0.148148148148148 0.0175438596491228
MIRNA MIRNA:hsa-miR-487a-3p hsa-miR-487a-3p 0.0334421632826742 53 117 4 0.0341880341880342 0.0754716981132075
MIRNA MIRNA:hsa-miR-186-5p hsa-miR-186-5p 0.0334421632826742 749 50 9 0.18 0.0120160213618158
MIRNA MIRNA:hsa-miR-21-5p hsa-miR-21-5p 0.033473795612255 607 115 13 0.11304347826087 0.0214168039538715
MIRNA MIRNA:hsa-miR-922 hsa-miR-922 0.033473795612255 160 69 5 0.072463768115942 0.03125
MIRNA MIRNA:hsa-miR-16-5p hsa-miR-16-5p 0.033473795612255 1556 31 10 0.32258064516129 0.006426735218509
MIRNA MIRNA:hsa-miR-3658 hsa-miR-3658 0.033473795612255 148 112 6 0.0535714285714286 0.0405405405405405
MIRNA MIRNA:hsa-miR-218-5p hsa-miR-218-5p 0.0336412195854947 814 77 12 0.155844155844156 0.0147420147420147
MIRNA MIRNA:hsa-miR-100-5p hsa-miR-100-5p 0.03366408165363 250 69 6 0.0869565217391304 0.024
MIRNA MIRNA:hsa-miR-487a-5p hsa-miR-487a-5p 0.03366408165363 38 79 3 0.0379746835443038 0.0789473684210526
MIRNA MIRNA:hsa-miR-30a-5p hsa-miR-30a-5p 0.03366408165363 730 53 9 0.169811320754717 0.0123287671232877
MIRNA MIRNA:hsa-miR-154-3p hsa-miR-154-3p 0.03366408165363 39 76 3 0.0394736842105263 0.0769230769230769
MIRNA MIRNA:hsa-miR-183-5p hsa-miR-183-5p 0.03366408165363 347 131 10 0.0763358778625954 0.0288184438040346
MIRNA MIRNA:hsa-miR-3148 hsa-miR-3148 0.03366408165363 243 70 6 0.0857142857142857 0.0246913580246914
MIRNA MIRNA:hsa-miR-4662b hsa-miR-4662b 0.0337375016361323 97 70 4 0.0571428571428571 0.0412371134020619
MIRNA MIRNA:hsa-miR-4426 hsa-miR-4426 0.0337375016361323 97 70 4 0.0571428571428571 0.0412371134020619
MIRNA MIRNA:hsa-miR-4647 hsa-miR-4647 0.0337375016361323 97 70 4 0.0571428571428571 0.0412371134020619
MIRNA MIRNA:hsa-miR-548ah-5p hsa-miR-548ah-5p 0.0351856654035522 318 76 7 0.0921052631578947 0.0220125786163522
MIRNA MIRNA:hsa-miR-3609 hsa-miR-3609 0.0352419290515657 319 76 7 0.0921052631578947 0.0219435736677116
MIRNA MIRNA:hsa-miR-487b-5p hsa-miR-487b-5p 0.0353397583970319 40 79 3 0.0379746835443038 0.075
MIRNA MIRNA:hsa-miR-4672 hsa-miR-4672 0.0363424406392924 131 136 6 0.0441176470588235 0.0458015267175573
MIRNA MIRNA:hsa-miR-2117 hsa-miR-2117 0.0391794900041879 56 59 3 0.0508474576271186 0.0535714285714286
MIRNA MIRNA:hsa-miR-16-2-3p hsa-miR-16-2-3p 0.0416345688682609 85 40 3 0.075 0.0352941176470588
MIRNA MIRNA:hsa-miR-1299 hsa-miR-1299 0.0445884887947532 89 40 3 0.075 0.0337078651685393
MIRNA MIRNA:hsa-miR-4644 hsa-miR-4644 0.0445884887947532 250 31 4 0.129032258064516 0.016
MIRNA MIRNA:hsa-miR-329-5p hsa-miR-329-5p 0.0445884887947532 103 75 4 0.0533333333333333 0.0388349514563107
MIRNA MIRNA:hsa-miR-1277-5p hsa-miR-1277-5p 0.0445884887947532 621 137 14 0.102189781021898 0.0225442834138486
MIRNA MIRNA:hsa-miR-132-3p hsa-miR-132-3p 0.0445884887947532 252 102 7 0.0686274509803922 0.0277777777777778
MIRNA MIRNA:hsa-miR-4306 hsa-miR-4306 0.0445884887947532 248 31 4 0.129032258064516 0.0161290322580645
MIRNA MIRNA:hsa-miR-1270 hsa-miR-1270 0.0447491313780177 101 36 3 0.0833333333333333 0.0297029702970297
MIRNA MIRNA:hsa-miR-620 hsa-miR-620 0.0454066740068077 102 36 3 0.0833333333333333 0.0294117647058824
MIRNA MIRNA:hsa-miR-3164 hsa-miR-3164 0.0483452338791779 59 64 3 0.046875 0.0508474576271186
MIRNA MIRNA:hsa-miR-195-3p hsa-miR-195-3p 0.0483452338791779 95 40 3 0.075 0.0315789473684211
MIRNA MIRNA:hsa-miR-548m hsa-miR-548m 0.0483452338791779 95 40 3 0.075 0.0315789473684211
MIRNA MIRNA:hsa-miR-191-5p hsa-miR-191-5p 0.0488040352964651 78 49 3 0.0612244897959184 0.0384615384615385
MIRNA MIRNA:hsa-miR-6820-3p hsa-miR-6820-3p 0.0489498042308587 60 64 3 0.046875 0.05
MIRNA MIRNA:hsa-miR-330-3p hsa-miR-330-3p 0.0492357402902652 146 136 6 0.0441176470588235 0.0410958904109589
MIRNA MIRNA:hsa-miR-3125 hsa-miR-3125 0.0492357402902652 183 75 5 0.0666666666666667 0.0273224043715847
MIRNA MIRNA:hsa-miR-6128 hsa-miR-6128 0.0492357402902652 98 40 3 0.075 0.0306122448979592
MIRNA MIRNA:hsa-miR-6859-5p hsa-miR-6859-5p 0.0492357402902652 182 75 5 0.0666666666666667 0.0274725274725275
REAC REAC:R-HSA-399997 Acetylcholine regulates insulin secretion 0.0178991232742605 10 115 3 0.0260869565217391 0.3
REAC REAC:R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 0.0178991232742605 35 76 4 0.0526315789473684 0.114285714285714
REAC REAC:R-HSA-71403 Citric acid cycle (TCA cycle) 0.0178991232742605 22 140 4 0.0285714285714286 0.181818181818182
REAC REAC:R-HSA-2682334 EPH-Ephrin signaling 0.0178991232742605 90 126 7 0.0555555555555556 0.0777777777777778
REAC REAC:R-HSA-3928662 EPHB-mediated forward signaling 0.0178991232742605 40 101 5 0.0495049504950495 0.125
REAC REAC:R-HSA-8863678 Neurodegenerative Diseases 0.022071268527324 21 79 3 0.0379746835443038 0.142857142857143
REAC REAC:R-HSA-5626467 RHO GTPases activate IQGAPs 0.022071268527324 32 119 4 0.0336134453781513 0.125
REAC REAC:R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 0.022071268527324 21 79 3 0.0379746835443038 0.142857142857143
REAC REAC:R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 0.022071268527324 13 130 3 0.0230769230769231 0.230769230769231
REAC REAC:R-HSA-9645723 Diseases of programmed cell death 0.0268378388912149 23 79 3 0.0379746835443038 0.130434782608696
REAC REAC:R-HSA-195258 RHO GTPase Effectors 0.0310258961889106 283 95 9 0.0947368421052632 0.0318021201413428
REAC REAC:R-HSA-9656223 Signaling by RAF1 mutants 0.0310258961889106 40 119 4 0.0336134453781513 0.1
REAC REAC:R-HSA-9649948 Signaling downstream of RAS mutants 0.0363278922874994 45 119 4 0.0336134453781513 0.0888888888888889
REAC REAC:R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 0.0363278922874994 45 119 4 0.0336134453781513 0.0888888888888889
REAC REAC:R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 0.0363278922874994 45 119 4 0.0336134453781513 0.0888888888888889
REAC REAC:R-HSA-6802949 Signaling by RAS mutants 0.0363278922874994 45 119 4 0.0336134453781513 0.0888888888888889
REAC REAC:R-HSA-422356 Regulation of insulin secretion 0.0367046950398255 78 119 5 0.0420168067226891 0.0641025641025641
REAC REAC:R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 0.0388424281394843 140 101 6 0.0594059405940594 0.0428571428571429
REAC REAC:R-HSA-442742 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 0.0388424281394843 26 106 3 0.0283018867924528 0.115384615384615
REAC REAC:R-HSA-6802957 Oncogenic MAPK signaling 0.0389531148596184 82 119 5 0.0420168067226891 0.0609756097560976
REAC REAC:R-HSA-437239 Recycling pathway of L1 0.0401855508317361 48 126 4 0.0317460317460317 0.0833333333333333
REAC REAC:R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 0.0402783764856355 53 57 3 0.0526315789473684 0.0566037735849057
REAC REAC:R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 0.0465755939281936 31 105 3 0.0285714285714286 0.0967741935483871
REAC REAC:R-HSA-5673000 RAF activation 0.048552488749776 33 106 3 0.0283018867924528 0.0909090909090909
REAC REAC:R-HSA-9664407 Parasite infection 0.048552488749776 113 101 5 0.0495049504950495 0.0442477876106195
REAC REAC:R-HSA-9664417 Leishmania phagocytosis 0.048552488749776 113 101 5 0.0495049504950495 0.0442477876106195
REAC REAC:R-HSA-9664422 FCGR3A-mediated phagocytosis 0.048552488749776 113 101 5 0.0495049504950495 0.0442477876106195
REAC REAC:R-HSA-199991 Membrane Trafficking 0.048552488749776 625 131 16 0.122137404580153 0.0256
TF TF:M00695_1 Factor: ETF; motif: GVGGMGG; match class: 1 6.299617898615e-05 7032 140 83 0.592857142857143 0.0118031854379977
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.000181169700537272 10430 140 105 0.75 0.0100671140939597
TF TF:M02036 Factor: WT1; motif: CGCCCCCNCN 0.000219649271673227 9767 135 97 0.718518518518519 0.00993140165864646
TF TF:M12351 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC 0.00034232401297625 12302 137 113 0.824817518248175 0.00918549829296049
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.00034232401297625 14473 140 127 0.907142857142857 0.00877496027084917
TF TF:M07039_1 Factor: ETF; motif: CCCCGCCCCYN; match class: 1 0.000487585649581091 13611 140 122 0.871428571428571 0.00896333847623246
TF TF:M09826 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC 0.000832083469606137 11467 135 105 0.777777777777778 0.00915671056073951
TF TF:M00982 Factor: KROX; motif: CCCGCCCCCRCCCC 0.000832083469606137 7815 137 82 0.598540145985402 0.0104926423544466
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.000832083469606137 10281 140 101 0.721428571428571 0.00982394708685926
TF TF:M07354 Factor: Egr-1; motif: GCGGGGGCGG 0.000832083469606137 7801 137 82 0.598540145985402 0.0105114728880913
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00143967228724431 13184 140 118 0.842857142857143 0.0089502427184466
TF TF:M03806 Factor: ZBTB7C; motif: GKCCCGGGCKG 0.00185676274404142 3031 131 41 0.312977099236641 0.0135268888155724
TF TF:M09723 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS 0.00231579155210015 10156 115 83 0.721739130434783 0.0081725088617566
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.00232207772671093 10419 140 100 0.714285714285714 0.00959785008158173
TF TF:M07380_1 Factor: E2F-4; motif: NTTTCSCGCC; match class: 1 0.00297234587526407 7965 135 80 0.592592592592593 0.0100439422473321
TF TF:M11601 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.00297234587526407 14823 140 126 0.9 0.00850030358227079
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.00398554098620587 8180 135 81 0.6 0.00990220048899755
TF TF:M07395 Factor: Sp1; motif: NGGGGCGGGGN 0.00520781453915762 10640 140 100 0.714285714285714 0.0093984962406015
TF TF:M10086 Factor: TAFII250; motif: RARRWGGCGGMGGNGR 0.00520781453915762 9262 137 89 0.64963503649635 0.00960915568991579
TF TF:M01199 Factor: RNF96; motif: BCCCGCRGCC 0.00520781453915762 8473 140 85 0.607142857142857 0.0100318659270624
TF TF:M04516_1 Factor: E2F-1; motif: TTTGGCGCCAAA; match class: 1 0.00520781453915762 10227 110 79 0.718181818181818 0.00772465043512271
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.00590447359911789 14096 140 121 0.864285714285714 0.00858399545970488
TF TF:M02089_1 Factor: E2F-3; motif: GGCGGGN; match class: 1 0.00590447359911789 9362 140 91 0.65 0.00972014526810511
TF TF:M09973 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN 0.0060478388536117 10853 140 101 0.721428571428571 0.00930618262231641
TF TF:M03893 Factor: WT1; motif: GNGGGGGCGGGG 0.00619193949280832 8290 140 83 0.592857142857143 0.0100120627261761
TF TF:M00933 Factor: Sp1; motif: CCCCGCCCCN 0.00619193949280832 9715 140 93 0.664285714285714 0.00957282552753474
TF TF:M00189 Factor: AP-2; motif: MKCCCSCNGGCG 0.00619193949280832 10621 130 93 0.715384615384615 0.00875623764240655
TF TF:M02089 Factor: E2F-3; motif: GGCGGGN 0.00619193949280832 13173 137 113 0.824817518248175 0.0085781522811812
TF TF:M11533_1 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN; match class: 1 0.00619193949280832 8705 138 85 0.615942028985507 0.00976450315910396
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00619193949280832 11053 140 102 0.728571428571429 0.00922826381977744
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.00619193949280832 9162 109 72 0.660550458715596 0.00785854616895874
TF TF:M04515_1 Factor: E2F-1; motif: WWTGGCGCCAAA; match class: 1 0.00663415639331249 12173 140 109 0.778571428571429 0.00895424299679619
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.00816208638901049 10233 140 96 0.685714285714286 0.00938141307534447
TF TF:M09895_1 Factor: E2F-6; motif: NGGGCGGGARRNN; match class: 1 0.00816208638901049 2711 139 37 0.266187050359712 0.0136481003319808
TF TF:M10026 Factor: PATZ; motif: GGGGNGGGGGMKGGRRNGGNRN 0.00820759214613293 8389 132 79 0.598484848484849 0.00941709381332698
TF TF:M10106_1 Factor: VDR; motif: NRGGTCANNGRGKTCA; match class: 1 0.008279861557655 1628 39 12 0.307692307692308 0.00737100737100737
TF TF:M03558_1 Factor: P73; motif: GNNNRRRCNTGCMNNTSASN; match class: 1 0.0086490107026389 822 86 13 0.151162790697674 0.0158150851581509
TF TF:M07084_1 Factor: E2F-4; motif: NGGCGGGAARN; match class: 1 0.0086490107026389 5437 139 60 0.431654676258993 0.0110354975170131
TF TF:M03895 Factor: CTCF; motif: WGCGCCMYCTAGYGGYN 0.0086490107026389 9251 140 89 0.635714285714286 0.0096205815587504
TF TF:M09826_1 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC; match class: 1 0.0086490107026389 7508 137 75 0.547445255474453 0.00998934469898775
TF TF:M04516 Factor: E2F-1; motif: TTTGGCGCCAAA 0.0086490107026389 11383 138 102 0.739130434782609 0.00896073091452165
TF TF:M04797 Factor: Egr-1; motif: CCGCCCMCG 0.0112925428010398 5116 139 57 0.410071942446043 0.0111415168100078
TF TF:M04515 Factor: E2F-1; motif: WWTGGCGCCAAA 0.0123293452582904 13334 140 115 0.821428571428571 0.00862456877156142
TF TF:M01303 Factor: SP1; motif: GGGGYGGGGNS 0.0137818131547601 7898 133 75 0.56390977443609 0.00949607495568498
TF TF:M00800 Factor: AP-2; motif: GSCCSCRGGCNRNRNN 0.0137818131547601 9119 114 73 0.640350877192982 0.00800526373505867
TF TF:M12085_1 Factor: ZNF501; motif: NNNCSACGCGAACAC; match class: 1 0.0137818131547601 2980 68 23 0.338235294117647 0.00771812080536913
TF TF:M09896_1 Factor: E2F-7; motif: GRGGCGGGAANNN; match class: 1 0.0141546638806067 4525 140 52 0.371428571428571 0.0114917127071823
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.01663958040556 14106 140 119 0.85 0.00843612647100525
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.01663958040556 13270 140 114 0.814285714285714 0.00859080633006782
TF TF:M01873 Factor: Egr-1; motif: GCGGGGGCGG 0.01663958040556 6738 137 68 0.496350364963504 0.0100920154348471
TF TF:M07250 Factor: E2F-1; motif: NNNSSCGCSAANN 0.01663958040556 10703 139 97 0.697841726618705 0.00906287956647669
TF TF:M11394_1 Factor: Erg; motif: NACMGGAARTN; match class: 1 0.0166960774073126 520 31 6 0.193548387096774 0.0115384615384615
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 0.0166960774073126 10494 130 90 0.692307692307692 0.00857632933104631
TF TF:M11530_1 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN; match class: 1 0.0168169746471206 13449 140 115 0.821428571428571 0.00855082162242546
TF TF:M03567 Factor: Sp2; motif: NYSGCCCCGCCCCCY 0.0168603516852815 7710 120 67 0.558333333333333 0.00869001297016861
TF TF:M10071 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG 0.0175639135799179 8495 140 82 0.585714285714286 0.00965273690406121
TF TF:M08523_1 Factor: E2F-1:TBR2; motif: NGGTGNNANGGCGCNNTNNCRNNN; match class: 1 0.0187162896713242 7423 140 74 0.528571428571429 0.00996901522295568
TF TF:M10072_1 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR; match class: 1 0.0187515781418311 6225 130 61 0.469230769230769 0.00979919678714859
TF TF:M07063 Factor: Sp1; motif: GGGGCGGGGC 0.0204530006038482 7696 119 66 0.554621848739496 0.00857588357588358
TF TF:M10435 Factor: Sp2; motif: GGGGCGGGG 0.0204530006038482 7696 119 66 0.554621848739496 0.00857588357588358
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.021206058058089 12401 140 108 0.771428571428571 0.00870897508265463
TF TF:M05444 Factor: CPBP; motif: NGGGCGG 0.0213709067192266 8578 140 82 0.585714285714286 0.00955933784098858
TF TF:M07250_1 Factor: E2F-1; motif: NNNSSCGCSAANN; match class: 1 0.0213709067192266 5515 47 25 0.531914893617021 0.00453309156844968
TF TF:M04202_1 Factor: CEBPD; motif: RTTRCGCAAY; match class: 1 0.0213709067192266 1980 111 24 0.216216216216216 0.0121212121212121
TF TF:M01199_1 Factor: RNF96; motif: BCCCGCRGCC; match class: 1 0.0213709067192266 4322 111 41 0.369369369369369 0.00948634891254049
TF TF:M05361 Factor: Sp6; motif: WGGGCGG 0.0213709067192266 8578 140 82 0.585714285714286 0.00955933784098858
TF TF:M05332 Factor: Sp2; motif: WGGGCGG 0.0213709067192266 8578 140 82 0.585714285714286 0.00955933784098858
TF TF:M04710_1 Factor: CHD2; motif: TCTCGCGAG; match class: 1 0.023050814202767 11477 95 72 0.757894736842105 0.00627341639801342
TF TF:M04184 Factor: NHLH1; motif: CGCAGCTGCK 0.0233646973806248 912 79 12 0.151898734177215 0.0131578947368421
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.0233646973806248 10253 109 75 0.688073394495413 0.00731493221496147
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.0236116664838419 11232 109 80 0.73394495412844 0.00712250712250712
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.0236116664838419 16244 140 130 0.928571428571429 0.00800295493720758
TF TF:M04953 Factor: Sp1; motif: GGNDGGRGGCGGGG 0.0251540131920935 8688 116 70 0.603448275862069 0.00805709023941068
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 0.0253212990749001 16263 140 130 0.928571428571429 0.00799360511590727
TF TF:M09896 Factor: E2F-7; motif: GRGGCGGGAANNN 0.0256869519947451 9927 140 91 0.65 0.00916691850508714
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.025789151911302 10488 137 93 0.678832116788321 0.00886727688787185
TF TF:M11410_1 Factor: etv3; motif: NNCGGAARTGSCAYTTCCGNT; match class: 1 0.0261216660923913 265 69 6 0.0869565217391304 0.0226415094339623
TF TF:M11531_1 Factor: E2F-2; motif: GCGCGCGCGYW; match class: 1 0.0261218281702117 12351 140 107 0.764285714285714 0.00866326613229698
TF TF:M00244 Factor: NGFI-C; motif: WTGCGTGGGYGG 0.0261218281702117 6184 110 52 0.472727272727273 0.00840879689521345
TF TF:M08878 Factor: EGR; motif: CGCCCCCGCNN 0.0261606387342123 7483 137 72 0.525547445255474 0.0096218094347187
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.0267661466819637 12729 120 95 0.791666666666667 0.00746327284154293
TF TF:M05480 Factor: TLX; motif: AAAAATCARK 0.0275445508577772 163 114 6 0.0526315789473684 0.0368098159509202
TF TF:M03807 Factor: SP2; motif: GNNGGGGGCGGGGSN 0.0278306341356852 8415 140 80 0.571428571428571 0.0095068330362448
TF TF:M11320_1 Factor: C/EBPdelta; motif: NRTTGCGYAAYN; match class: 1 0.0278318189020423 2586 116 29 0.25 0.0112142304717711
TF TF:M07380 Factor: E2F-4; motif: NTTTCSCGCC 0.0284682309827639 13022 140 111 0.792857142857143 0.00852403624635233
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.0303746490955764 14873 140 122 0.871428571428571 0.00820278356753849
TF TF:M04203 Factor: CEBPE; motif: NTTRCGCAAY 0.0311168652294401 1058 127 17 0.133858267716535 0.0160680529300567
TF TF:M04823_1 Factor: E2F-4; motif: NNTTCCCGCCNN; match class: 1 0.0311710742914802 7850 109 61 0.559633027522936 0.00777070063694267
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 0.0321425791231716 13929 137 114 0.832116788321168 0.00818436355804437
TF TF:M05467_1 Factor: Sall1; motif: NGGTCCKRGKRA; match class: 1 0.0321425791231716 568 64 8 0.125 0.0140845070422535
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.0321425791231716 13227 140 112 0.8 0.00846752854010736
TF TF:M00915 Factor: AP-2; motif: SNNNCCNCAGGCN 0.0330243256046974 9612 140 88 0.628571428571429 0.00915522263836871
TF TF:M01972 Factor: EGR-1; motif: TGCGTGGGCGK 0.0332541475712874 5360 139 56 0.402877697841727 0.0104477611940299
TF TF:M10093 Factor: TEF-3; motif: RCATTCCWGNNNN 0.0332541475712874 1679 24 8 0.333333333333333 0.00476474091721263
TF TF:M01869_1 Factor: C/EBPgamma; motif: NRTKRSRMAAKN; match class: 1 0.0332541475712874 390 94 8 0.0851063829787234 0.0205128205128205
TF TF:M04201 Factor: CEBPB; motif: ATTRCGCAAY 0.0332541475712874 4048 134 44 0.328358208955224 0.0108695652173913
TF TF:M07206_1 Factor: E2F-1; motif: NGGGCGGGARV; match class: 1 0.0332541475712874 10849 109 77 0.706422018348624 0.0070974283344087
TF TF:M11401_1 Factor: Fli-1; motif: NACCGGATATCCGGTN; match class: 1 0.0332541475712874 11801 90 69 0.766666666666667 0.00584696212185408
TF TF:M07039 Factor: ETF; motif: CCCCGCCCCYN 0.0332541475712874 16384 140 130 0.928571428571429 0.0079345703125
TF TF:M09973_1 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN; match class: 1 0.0332541475712874 6607 140 66 0.471428571428571 0.00998940517632814
TF TF:M11477 Factor: AP-2beta; motif: NSCCYNRGGSN 0.0332541475712874 8252 20 16 0.8 0.00193892389723703
TF TF:M04146 Factor: TFAP2A; motif: YGCCCNNRGGCN 0.0332541475712874 6552 36 22 0.611111111111111 0.00335775335775336
TF TF:M01837 Factor: FKLF; motif: BGGGNGGVMD 0.0332541475712874 5442 111 47 0.423423423423423 0.00863653068724734
TF TF:M06154 Factor: ZNF132; motif: NTTRGAAATGTTYM 0.0335213142654089 66 49 3 0.0612244897959184 0.0454545454545455
TF TF:M07226 Factor: SP1; motif: NCCCCKCCCCC 0.0349616638201449 8292 119 68 0.571428571428571 0.00820067534973468
TF TF:M00938_1 Factor: E2F-1; motif: TTGGCGCGRAANNGNM; match class: 1 0.03578853464836 2573 109 27 0.247706422018349 0.0104935872522347
TF TF:M01219 Factor: SP1:SP3; motif: CCSCCCCCYCC 0.0361990604431978 6812 137 66 0.481751824817518 0.0096887844979448
TF TF:M07208 Factor: EGR1; motif: NCNCCGCCCCCGCN 0.0365330512933056 6183 131 59 0.450381679389313 0.00954229338508815
TF TF:M10084_1 Factor: SF-1; motif: NYYCAAGGYCA; match class: 1 0.0375296447718437 552 7 3 0.428571428571429 0.00543478260869565
TF TF:M07397 Factor: ZBP89; motif: CCCCKCCCCCNN 0.0378755129949369 7143 134 67 0.5 0.00937981240375193
TF TF:M11678 Factor: IRF-7; motif: NNGAAAGTGAAANTR 0.0378755129949369 179 78 5 0.0641025641025641 0.0279329608938547
TF TF:M07277 Factor: BTEB2; motif: RGGGNGKGGN 0.0378755129949369 8492 119 69 0.579831932773109 0.00812529439472445
TF TF:M07087_1 Factor: Elf-1; motif: NRANCMGGAAGTG; match class: 1 0.0389038879834861 155 23 3 0.130434782608696 0.0193548387096774
TF TF:M00483_1 Factor: ATF6; motif: TGACGTGG; match class: 1 0.0389624527478378 246 87 6 0.0689655172413793 0.024390243902439
TF TF:M01253_1 Factor: CNOT3; motif: GGCCGCGSSS; match class: 1 0.0389624527478378 1026 137 17 0.124087591240876 0.0165692007797271
TF TF:M09667_1 Factor: TEF-3; motif: RCATTCCWGNNNN; match class: 1 0.0397829640212488 32 113 3 0.0265486725663717 0.09375
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 0.0416129496183658 14575 137 117 0.854014598540146 0.00802744425385935
TF TF:M01783_1 Factor: SP2; motif: GGGCGGGAC; match class: 1 0.0416129496183658 4333 72 28 0.388888888888889 0.00646203554119548
TF TF:M02036_1 Factor: WT1; motif: CGCCCCCNCN; match class: 1 0.0420330430127724 5290 137 54 0.394160583941606 0.0102079395085066
TF TF:M00938 Factor: E2F-1; motif: TTGGCGCGRAANNGNM 0.0431040554205004 7334 134 68 0.507462686567164 0.0092718843741478
TF TF:M00008 Factor: Sp1; motif: GGGGCGGGGT 0.0431040554205004 10055 119 78 0.65546218487395 0.00775733465937345
TF TF:M10098_1 Factor: DP-1; motif: NRNNGGCGGGAANN; match class: 1 0.0436842967318437 2168 131 27 0.206106870229008 0.0124538745387454
TF TF:M11401 Factor: Fli-1; motif: NACCGGATATCCGGTN 0.0437821425881668 11952 90 69 0.766666666666667 0.00577309236947791
TF TF:M07040_1 Factor: GKLF; motif: NNRRGRRNGNSNNN; match class: 1 0.0444675663708624 8156 118 66 0.559322033898305 0.00809220205983325
TF TF:M07040 Factor: GKLF; motif: NNRRGRRNGNSNNN 0.0445539611241628 12705 118 92 0.779661016949153 0.00724124360487997
TF TF:M08205_1 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1 0.0445539611241628 10438 129 86 0.666666666666667 0.00823912626940027
TF TF:M07329 Factor: Osx; motif: CCNCCCCCNNN 0.0445539611241628 6803 134 64 0.477611940298507 0.0094076142878142
TF TF:M11671 Factor: IRF-5; motif: NCGAAACCGAAACY 0.0445539611241628 389 103 8 0.0776699029126214 0.0205655526992288
TF TF:M07436 Factor: WT1; motif: NNGGGNGGGSGN 0.0445539611241628 6182 117 53 0.452991452991453 0.00857327725655128
TF TF:M07249_1 Factor: ctcf; motif: CCNCNAGRKGGCRSTN; match class: 1 0.0445539611241628 2074 42 12 0.285714285714286 0.00578592092574735
TF TF:M08487 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG 0.0445539611241628 13942 111 93 0.837837837837838 0.00667049203844499
TF TF:M09967_1 Factor: AP-2rep; motif: NGGGGCGGGGC; match class: 1 0.0445539611241628 1379 134 20 0.149253731343284 0.0145032632342277
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.0445539611241628 10357 140 92 0.657142857142857 0.00888288114318818
TF TF:M08910_1 Factor: C/EBPBETA; motif: KRTTGCGYAAY; match class: 1 0.0445539611241628 3194 138 37 0.268115942028986 0.0115842204132749
TF TF:M10530 Factor: sp4; motif: NNNGCYCCGCCCCCY 0.0445539611241628 8227 140 77 0.55 0.00935942627932418
TF TF:M04611_1 Factor: FOXM1; motif: NAGASTGATTA; match class: 1 0.0445539611241628 3507 4 4 1 0.00114057599087539
TF TF:M04152_1 Factor: TFAP2C; motif: NGCCCNNRGGCA; match class: 1 0.0458456032199085 5580 35 19 0.542857142857143 0.00340501792114695
TF TF:M04896 Factor: AP-2alpha; motif: NNNGSCCTGRGGSN 0.0458621250497539 5780 133 56 0.421052631578947 0.00968858131487889
TF TF:M11418_1 Factor: ER81; motif: NRCMGGAWGNN; match class: 1 0.0471730938310407 549 29 5 0.172413793103448 0.00910746812386157
TF TF:M04016 Factor: IRF5; motif: CCGAAACCGAAACY 0.0475584258319182 314 130 8 0.0615384615384615 0.0254777070063694
TF TF:M04635_1 Factor: TEF-5; motif: AAAAATAT; match class: 1 0.0475584258319182 576 41 6 0.146341463414634 0.0104166666666667
TF TF:M11393 Factor: Erg; motif: NACCGGATATCCGGTN 0.0481684971112436 14105 51 46 0.901960784313726 0.0032612548741581
TF TF:M11528 Factor: E2F-2; motif: NTTTTGGCGCCAWWWN 0.0481951015713899 10373 125 83 0.664 0.00800154246601755
TF TF:M09966 Factor: Kaiso; motif: SARNYCTCGCGAGAN 0.0481951015713899 2356 93 22 0.236559139784946 0.00933786078098472
TF TF:M01104 Factor: MOVO-B; motif: GNGGGGG 0.0485233765079529 10261 140 91 0.65 0.00886853133222883
TF TF:M09591 Factor: AP-2gamma; motif: NTGSCCTGRGGSNN 0.0485233765079529 8337 133 74 0.556390977443609 0.0088760945184119
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.0485233765079529 14593 140 119 0.85 0.00815459466867676
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.0485233765079529 14429 140 118 0.842857142857143 0.00817797491163629
TF TF:M08910 Factor: C/EBPBETA; motif: KRTTGCGYAAY 0.0485233765079529 4674 118 43 0.364406779661017 0.00919982884039367
TF TF:M00976_1 Factor: AhR,; motif: NRCGTGNGN; match class: 1 0.0485233765079529 1011 5 3 0.6 0.0029673590504451
TF TF:M09658 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS 0.0485233765079529 5262 115 46 0.4 0.00874192322310908
TF TF:M12227 Factor: ZIC4; motif: NNCCNCCCRYNGYGN 0.0485233765079529 11063 136 94 0.691176470588235 0.00849679110548676
TF TF:M00196_1 Factor: Sp1; motif: NGGGGGCGGGGYN; match class: 1 0.0485233765079529 5919 139 59 0.424460431654676 0.00996789998310525
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.0485500040054565 11423 134 95 0.708955223880597 0.00831655432023111
TF TF:M11490 Factor: LBP-1; motif: NRCCGGTNNNNACCGGYN 0.0485500040054565 6748 92 46 0.5 0.00681683461766449
TF TF:M04748 Factor: GABP-alpha; motif: AACCGGAAR 0.0489443060249256 16027 119 109 0.915966386554622 0.00680102327322643
TF TF:M09603 Factor: Egr-1; motif: NNNNNGYGKGGGNGGGNN 0.0489443060249256 4627 140 49 0.35 0.010590015128593
TF TF:M11397_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.0489443060249256 11731 95 71 0.747368421052632 0.00605233995396812
TF TF:M10003 Factor: NF-kappaB1; motif: AGGGAAAK 0.0489443060249256 1983 6 4 0.666666666666667 0.00201714573877963
TF TF:M03899 Factor: EGR4; motif: NNMCGCCCACGCANNN 0.0489443060249256 2037 81 18 0.222222222222222 0.00883652430044183
WP WP:WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) 0.00197256147364687 16 140 5 0.0357142857142857 0.3125
WP WP:WP524 G13 Signaling Pathway 0.00435179584485668 40 119 6 0.0504201680672269 0.15
WP WP:WP78 TCA Cycle (aka Krebs or citric acid cycle) 0.0185385595926348 18 140 4 0.0285714285714286 0.222222222222222

pEpiTd27 transcription factor target enrichment of top program genes

TF enrichment of pEpiTd27
Possible regulators of activation of pEpiTd27 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.