pEpiTp20 program activity among Epithelial cells

Activation of pEpiTp20
pEpiTp20 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpiTp20 by different cell subtypes
pEpiTp20 gene program activation among cells of different subtypes (Epithelial cells).

pEpiTp20 top program genes

Top genes of pEpiTp20 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpiTp20 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpiTp20
pEpiTp20 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0060341 regulation of cellular localization 0.0021407566344886 851 56 12 0.214285714285714 0.0141010575793184
GO:BP GO:0021762 substantia nigra development 0.0021407566344886 46 50 4 0.08 0.0869565217391304
GO:BP GO:0031346 positive regulation of cell projection organization 0.0021407566344886 359 26 6 0.230769230769231 0.0167130919220056
GO:BP GO:0061024 membrane organization 0.0021407566344886 973 57 13 0.228070175438596 0.013360739979445
GO:BP GO:0065003 protein-containing complex assembly 0.0021407566344886 1680 63 18 0.285714285714286 0.0107142857142857
GO:BP GO:0043933 protein-containing complex subunit organization 0.0021407566344886 1963 63 20 0.317460317460317 0.0101884870096791
GO:BP GO:0051641 cellular localization 0.0021407566344886 3541 60 27 0.45 0.0076249646992375
GO:BP GO:0051130 positive regulation of cellular component organization 0.0021407566344886 1153 26 10 0.384615384615385 0.00867302688638335
GO:BP GO:0006996 organelle organization 0.0021407566344886 4104 58 30 0.517241379310345 0.00730994152046784
GO:BP GO:0051649 establishment of localization in cell 0.0021407566344886 2813 60 24 0.4 0.00853181656594383
GO:BP GO:0032970 regulation of actin filament-based process 0.0021407566344886 406 41 8 0.195121951219512 0.0197044334975369
GO:BP GO:1901019 regulation of calcium ion transmembrane transporter activity 0.00317503175705447 88 11 3 0.272727272727273 0.0340909090909091
GO:BP GO:0032880 regulation of protein localization 0.00317503175705447 922 56 12 0.214285714285714 0.0130151843817787
GO:BP GO:0044403 biological process involved in symbiotic interaction 0.00317503175705447 1001 60 13 0.216666666666667 0.012987012987013
GO:BP GO:0006879 cellular iron ion homeostasis 0.00319704040554508 69 43 4 0.0930232558139535 0.0579710144927536
GO:BP GO:0048857 neural nucleus development 0.00407025138367246 64 50 4 0.08 0.0625
GO:BP GO:0051493 regulation of cytoskeleton organization 0.00421853114674497 531 32 7 0.21875 0.0131826741996234
GO:BP GO:0046907 intracellular transport 0.00446080674624391 1767 60 17 0.283333333333333 0.00962082625919638
GO:BP GO:0051640 organelle localization 0.00446080674624391 668 57 10 0.175438596491228 0.0149700598802395
GO:BP GO:0006875 cellular metal ion homeostasis 0.00446080674624391 593 7 4 0.571428571428571 0.00674536256323777
GO:BP GO:0016032 viral process 0.00476675953412832 942 60 12 0.2 0.0127388535031847
GO:BP GO:0055072 iron ion homeostasis 0.00476675953412832 86 43 4 0.0930232558139535 0.0465116279069767
GO:BP GO:0044237 cellular metabolic process 0.00476675953412832 10871 83 67 0.807228915662651 0.00616318645938736
GO:BP GO:0030003 cellular cation homeostasis 0.00504655206699732 673 7 4 0.571428571428571 0.00594353640416048
GO:BP GO:0045184 establishment of protein localization 0.00504655206699732 2035 70 20 0.285714285714286 0.00982800982800983
GO:BP GO:0055065 metal ion homeostasis 0.00504655206699732 667 7 4 0.571428571428571 0.00599700149925037
GO:BP GO:0006873 cellular ion homeostasis 0.00527494701118554 687 7 4 0.571428571428571 0.00582241630276565
GO:BP GO:0051128 regulation of cellular component organization 0.00547553384323044 2412 39 15 0.384615384615385 0.00621890547263682
GO:BP GO:1903793 positive regulation of anion transport 0.00547553384323044 504 80 10 0.125 0.0198412698412698
GO:BP GO:0010638 positive regulation of organelle organization 0.00567837474781036 603 23 6 0.260869565217391 0.00995024875621891
GO:BP GO:1903169 regulation of calcium ion transmembrane transport 0.00567837474781036 158 11 3 0.272727272727273 0.0189873417721519
GO:BP GO:0015031 protein transport 0.00567837474781036 1929 70 19 0.271428571428571 0.00984966303784344
GO:BP GO:0032386 regulation of intracellular transport 0.00567837474781036 367 54 7 0.12962962962963 0.0190735694822888
GO:BP GO:0051051 negative regulation of transport 0.00567837474781036 474 70 9 0.128571428571429 0.0189873417721519
GO:BP GO:0048193 Golgi vesicle transport 0.00567837474781036 382 69 8 0.115942028985507 0.0209424083769634
GO:BP GO:0034622 cellular protein-containing complex assembly 0.00567837474781036 1107 63 13 0.206349206349206 0.011743450767841
GO:BP GO:0110053 regulation of actin filament organization 0.00567837474781036 284 30 5 0.166666666666667 0.0176056338028169
GO:BP GO:0055080 cation homeostasis 0.00567837474781036 750 7 4 0.571428571428571 0.00533333333333333
GO:BP GO:0098771 inorganic ion homeostasis 0.00567837474781036 761 7 4 0.571428571428571 0.00525624178712221
GO:BP GO:0022607 cellular component assembly 0.00580310467339119 3010 63 23 0.365079365079365 0.00764119601328904
GO:BP GO:0030901 midbrain development 0.00580310467339119 90 50 4 0.08 0.0444444444444444
GO:BP GO:0033157 regulation of intracellular protein transport 0.00599056591266203 264 54 6 0.111111111111111 0.0227272727272727
GO:BP GO:0050801 ion homeostasis 0.00599056591266203 808 7 4 0.571428571428571 0.00495049504950495
GO:BP GO:0044085 cellular component biogenesis 0.00599056591266203 3257 63 24 0.380952380952381 0.00736874424316856
GO:BP GO:0055082 cellular chemical homeostasis 0.00599056591266203 841 12 5 0.416666666666667 0.00594530321046373
GO:BP GO:0008104 protein localization 0.00599056591266203 2770 60 21 0.35 0.0075812274368231
GO:BP GO:0015833 peptide transport 0.00599056591266203 1971 70 19 0.271428571428571 0.00963977676306443
GO:BP GO:0033043 regulation of organelle organization 0.00616565546104968 1203 38 10 0.263157894736842 0.00831255195344971
GO:BP GO:1902905 positive regulation of supramolecular fiber organization 0.00621611504523355 214 23 4 0.173913043478261 0.0186915887850467
GO:BP GO:0071840 cellular component organization or biogenesis 0.00645707525128907 6760 71 42 0.591549295774648 0.00621301775147929
GO:BP GO:0070979 protein K11-linked ubiquitination 0.00655389093698554 29 67 3 0.0447761194029851 0.103448275862069
GO:BP GO:0042886 amide transport 0.00655389093698554 2007 70 19 0.271428571428571 0.00946686596910812
GO:BP GO:0016043 cellular component organization 0.00655389093698554 6566 58 35 0.603448275862069 0.00533049040511727
GO:BP GO:0046916 cellular transition metal ion homeostasis 0.00655389093698554 116 43 4 0.0930232558139535 0.0344827586206897
GO:BP GO:0051495 positive regulation of cytoskeleton organization 0.00720649498635374 231 23 4 0.173913043478261 0.0173160173160173
GO:BP GO:1903827 regulation of cellular protein localization 0.00758924506707605 572 80 10 0.125 0.0174825174825175
GO:BP GO:0022406 membrane docking 0.00758924506707605 183 12 3 0.25 0.0163934426229508
GO:BP GO:0097581 lamellipodium organization 0.00758924506707605 91 23 3 0.130434782608696 0.032967032967033
GO:BP GO:0043270 positive regulation of ion transport 0.00801691257564428 694 80 11 0.1375 0.015850144092219
GO:BP GO:0120035 regulation of plasma membrane bounded cell projection organization 0.00814551012556404 638 26 6 0.230769230769231 0.00940438871473354
GO:BP GO:0051223 regulation of protein transport 0.00852922502479692 586 80 10 0.125 0.0170648464163823
GO:BP GO:0019725 cellular homeostasis 0.00882643909646194 981 7 4 0.571428571428571 0.00407747196738022
GO:BP GO:0030029 actin filament-based process 0.00886553067282396 808 30 7 0.233333333333333 0.00866336633663366
GO:BP GO:0031344 regulation of cell projection organization 0.00886553067282396 656 26 6 0.230769230769231 0.00914634146341463
GO:BP GO:0030832 regulation of actin filament length 0.00886553067282396 194 30 4 0.133333333333333 0.0206185567010309
GO:BP GO:0008064 regulation of actin polymerization or depolymerization 0.00886553067282396 193 30 4 0.133333333333333 0.0207253886010363
GO:BP GO:0051222 positive regulation of protein transport 0.00886553067282396 329 50 6 0.12 0.0182370820668693
GO:BP GO:0055076 transition metal ion homeostasis 0.00939831727560742 138 43 4 0.0930232558139535 0.0289855072463768
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.00939831727560742 460 37 6 0.162162162162162 0.0130434782608696
GO:BP GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 0.00939831727560742 106 23 3 0.130434782608696 0.0283018867924528
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.00939831727560742 366 30 5 0.166666666666667 0.0136612021857923
GO:BP GO:0070201 regulation of establishment of protein localization 0.00993298297706617 611 80 10 0.125 0.016366612111293
GO:BP GO:0006900 vesicle budding from membrane 0.00997151741153548 107 57 4 0.0701754385964912 0.0373831775700935
GO:BP GO:1904951 positive regulation of establishment of protein localization 0.00997151741153548 345 50 6 0.12 0.0173913043478261
GO:BP GO:0016050 vesicle organization 0.0101414301009394 341 71 7 0.0985915492957746 0.0205278592375367
GO:BP GO:0044070 regulation of anion transport 0.0101414301009394 896 56 10 0.178571428571429 0.0111607142857143
GO:BP GO:0090087 regulation of peptide transport 0.0102203945504671 618 80 10 0.125 0.0161812297734628
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.0104345544236614 387 30 5 0.166666666666667 0.0129198966408269
GO:BP GO:0032535 regulation of cellular component size 0.0104345544236614 388 30 5 0.166666666666667 0.0128865979381443
GO:BP GO:0032388 positive regulation of intracellular transport 0.010444250115237 229 50 5 0.1 0.0218340611353712
GO:BP GO:0006812 cation transport 0.010444250115237 1197 11 5 0.454545454545455 0.00417710944026733
GO:BP GO:0051924 regulation of calcium ion transport 0.0109462520663192 259 11 3 0.272727272727273 0.0115830115830116
GO:BP GO:0032412 regulation of ion transmembrane transporter activity 0.0110091608135894 270 11 3 0.272727272727273 0.0111111111111111
GO:BP GO:0051050 positive regulation of transport 0.0110091608135894 923 56 10 0.178571428571429 0.0108342361863489
GO:BP GO:0034766 negative regulation of ion transmembrane transport 0.0110091608135894 131 50 4 0.08 0.0305343511450382
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.0110091608135894 540 23 5 0.217391304347826 0.00925925925925926
GO:BP GO:0010959 regulation of metal ion transport 0.0110091608135894 268 11 3 0.272727272727273 0.0111940298507463
GO:BP GO:0051656 establishment of organelle localization 0.0110091608135894 445 57 7 0.12280701754386 0.0157303370786517
GO:BP GO:0033365 protein localization to organelle 0.0110091608135894 1017 70 12 0.171428571428571 0.0117994100294985
GO:BP GO:0034763 negative regulation of transmembrane transport 0.0110091608135894 132 50 4 0.08 0.0303030303030303
GO:BP GO:0034613 cellular protein localization 0.0110091608135894 2014 70 18 0.257142857142857 0.00893743793445879
GO:BP GO:0008154 actin polymerization or depolymerization 0.0110091608135894 223 30 4 0.133333333333333 0.0179372197309417
GO:BP GO:0051651 maintenance of location in cell 0.0112256162030129 223 54 5 0.0925925925925926 0.0224215246636771
GO:BP GO:0070727 cellular macromolecule localization 0.0112256162030129 2024 70 18 0.257142857142857 0.00889328063241107
GO:BP GO:0006413 translational initiation 0.0112256162030129 201 60 5 0.0833333333333333 0.0248756218905473
GO:BP GO:1903749 positive regulation of establishment of protein localization to mitochondrion 0.0112777030064621 58 50 3 0.06 0.0517241379310345
GO:BP GO:0022898 regulation of transmembrane transporter activity 0.0112777030064621 281 11 3 0.272727272727273 0.0106761565836299
GO:BP GO:0043271 negative regulation of ion transport 0.0115804324558701 349 54 6 0.111111111111111 0.0171919770773639
GO:BP GO:0006811 ion transport 0.0120450688009798 3661 12 8 0.666666666666667 0.0021851953018301
GO:BP GO:0048878 chemical homeostasis 0.0120450688009798 1229 7 4 0.571428571428571 0.0032546786004882
GO:BP GO:0008152 metabolic process 0.0120553393668817 11827 83 68 0.819277108433735 0.00574955610044813
GO:BP GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 0.0120553393668817 135 23 3 0.130434782608696 0.0222222222222222
GO:BP GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 0.0120553393668817 135 23 3 0.130434782608696 0.0222222222222222
GO:BP GO:0032409 regulation of transporter activity 0.0120553393668817 297 11 3 0.272727272727273 0.0101010101010101
GO:BP GO:0006397 mRNA processing 0.0120553393668817 532 82 9 0.109756097560976 0.0169172932330827
GO:BP GO:0038094 Fc-gamma receptor signaling pathway 0.0121026698046371 137 23 3 0.130434782608696 0.0218978102189781
GO:BP GO:0009894 regulation of catabolic process 0.0126751348289593 1033 4 3 0.75 0.00290416263310745
GO:BP GO:0097435 supramolecular fiber organization 0.0128199897842575 734 38 7 0.184210526315789 0.00953678474114441
GO:BP GO:0044087 regulation of cellular component biogenesis 0.0128199897842575 990 37 8 0.216216216216216 0.00808080808080808
GO:BP GO:0002431 Fc receptor mediated stimulatory signaling pathway 0.0128199897842575 141 23 3 0.130434782608696 0.0212765957446809
GO:BP GO:0007015 actin filament organization 0.0130168218934781 445 30 5 0.166666666666667 0.0112359550561798
GO:BP GO:0032413 negative regulation of ion transmembrane transporter activity 0.0137736216729589 81 41 3 0.0731707317073171 0.037037037037037
GO:BP GO:0070588 calcium ion transmembrane transport 0.0137736216729589 320 11 3 0.272727272727273 0.009375
GO:BP GO:0043269 regulation of ion transport 0.0144339708329963 1379 56 12 0.214285714285714 0.00870195794053662
GO:BP GO:0098662 inorganic cation transmembrane transport 0.0152634478727676 794 11 4 0.363636363636364 0.00503778337531486
GO:BP GO:0051049 regulation of transport 0.0153114020664142 1809 56 14 0.25 0.00773908236594804
GO:BP GO:0071705 nitrogen compound transport 0.0153180722693397 2322 70 19 0.271428571428571 0.00818260120585702
GO:BP GO:0072657 protein localization to membrane 0.0153180722693397 665 70 9 0.128571428571429 0.0135338345864662
GO:BP GO:0033036 macromolecule localization 0.0153180722693397 3218 56 20 0.357142857142857 0.00621504039776259
GO:BP GO:1903747 regulation of establishment of protein localization to mitochondrion 0.0153180722693397 72 50 3 0.06 0.0416666666666667
GO:BP GO:0006220 pyrimidine nucleotide metabolic process 0.0153180722693397 50 71 3 0.0422535211267606 0.06
GO:BP GO:0008380 RNA splicing 0.0154198501941601 456 82 8 0.0975609756097561 0.0175438596491228
GO:BP GO:0070647 protein modification by small protein conjugation or removal 0.0154198501941601 1184 4 3 0.75 0.00253378378378378
GO:BP GO:1905475 regulation of protein localization to membrane 0.015469155536714 201 70 5 0.0714285714285714 0.0248756218905473
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.015469155536714 3087 75 24 0.32 0.00777453838678328
GO:BP GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 0.0156104220992748 206 69 5 0.072463768115942 0.0242718446601942
GO:BP GO:1904062 regulation of cation transmembrane transport 0.0156858785639938 360 11 3 0.272727272727273 0.00833333333333333
GO:BP GO:0032410 negative regulation of transporter activity 0.0158697535256377 92 41 3 0.0731707317073171 0.0326086956521739
GO:BP GO:0120036 plasma membrane bounded cell projection organization 0.0158697535256377 1569 26 8 0.307692307692308 0.00509878903760357
GO:BP GO:1903047 mitotic cell cycle process 0.0160698425978718 911 43 8 0.186046511627907 0.00878155872667398
GO:BP GO:0006810 transport 0.0163939053396445 5224 12 9 0.75 0.00172281776416539
GO:BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 0.0163939053396445 361 82 7 0.0853658536585366 0.0193905817174515
GO:BP GO:0000398 mRNA splicing, via spliceosome 0.0163939053396445 361 82 7 0.0853658536585366 0.0193905817174515
GO:BP GO:0006793 phosphorus metabolic process 0.0164034177025739 3114 75 24 0.32 0.00770712909441233
GO:BP GO:1904063 negative regulation of cation transmembrane transport 0.0167403651896047 96 41 3 0.0731707317073171 0.03125
GO:BP GO:0000375 RNA splicing, via transesterification reactions 0.0167403651896047 364 82 7 0.0853658536585366 0.0192307692307692
GO:BP GO:0006909 phagocytosis 0.0167403651896047 387 23 4 0.173913043478261 0.0103359173126615
GO:BP GO:0030030 cell projection organization 0.0172170101135573 1609 26 8 0.307692307692308 0.00497203231821007
GO:BP GO:0046902 regulation of mitochondrial membrane permeability 0.0172170101135573 80 50 3 0.06 0.0375
GO:BP GO:0098660 inorganic ion transmembrane transport 0.0172170101135573 883 11 4 0.363636363636364 0.00453001132502831
GO:BP GO:0090316 positive regulation of intracellular protein transport 0.0172170101135573 186 80 5 0.0625 0.0268817204301075
GO:BP GO:0006412 translation 0.0172213942705746 764 77 10 0.12987012987013 0.0130890052356021
GO:BP GO:0051234 establishment of localization 0.0172213942705746 5372 62 30 0.483870967741935 0.00558451228592703
GO:BP GO:0070936 protein K48-linked ubiquitination 0.0174474004682687 61 67 3 0.0447761194029851 0.0491803278688525
GO:BP GO:0090066 regulation of anatomical structure size 0.0174474004682687 518 30 5 0.166666666666667 0.00965250965250965
GO:BP GO:0042176 regulation of protein catabolic process 0.0179079929665396 401 11 3 0.272727272727273 0.00748129675810474
GO:BP GO:0006886 intracellular protein transport 0.0180183664304731 1186 35 8 0.228571428571429 0.00674536256323777
GO:BP GO:0051248 negative regulation of protein metabolic process 0.0180183664304731 1151 9 4 0.444444444444444 0.00347523892267593
GO:BP GO:0098655 cation transmembrane transport 0.018099975618575 914 11 4 0.363636363636364 0.00437636761487965
GO:BP GO:0120032 regulation of plasma membrane bounded cell projection assembly 0.01914454657258 190 23 3 0.130434782608696 0.0157894736842105
GO:BP GO:0043043 peptide biosynthetic process 0.0193518709319136 790 77 10 0.12987012987013 0.0126582278481013
GO:BP GO:0060491 regulation of cell projection assembly 0.0193518709319136 192 23 3 0.130434782608696 0.015625
GO:BP GO:0032446 protein modification by small protein conjugation 0.0193518709319136 973 43 8 0.186046511627907 0.00822199383350463
GO:BP GO:0043604 amide biosynthetic process 0.0196370717276045 932 77 11 0.142857142857143 0.0118025751072961
GO:BP GO:0016071 mRNA metabolic process 0.0196390325850503 874 82 11 0.134146341463415 0.0125858123569794
GO:BP GO:0006816 calcium ion transport 0.0198236279514748 436 11 3 0.272727272727273 0.00688073394495413
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.0198236279514748 263 37 4 0.108108108108108 0.0152091254752852
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 0.0200701270676225 174 56 4 0.0714285714285714 0.0229885057471264
GO:BP GO:0140056 organelle localization by membrane tethering 0.0200701270676225 174 56 4 0.0714285714285714 0.0229885057471264
GO:BP GO:0048024 regulation of mRNA splicing, via spliceosome 0.020285623639635 119 82 4 0.0487804878048781 0.0336134453781513
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 0.0206570336371518 2255 60 16 0.266666666666667 0.00709534368070953
GO:BP GO:0038093 Fc receptor signaling pathway 0.0209850360490804 238 70 5 0.0714285714285714 0.0210084033613445
GO:BP GO:0090559 regulation of membrane permeability 0.0209850360490804 95 50 3 0.06 0.0315789473684211
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 0.021376814577893 5017 79 34 0.430379746835443 0.00677695834163843
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 0.0215636217673247 182 56 4 0.0714285714285714 0.021978021978022
GO:BP GO:0016192 vesicle-mediated transport 0.0217530215582023 2180 57 15 0.263157894736842 0.00688073394495413
GO:BP GO:0043312 neutrophil degranulation 0.0217845509730338 482 22 4 0.181818181818182 0.00829875518672199
GO:BP GO:0002283 neutrophil activation involved in immune response 0.0221027899124243 485 22 4 0.181818181818182 0.00824742268041237
GO:BP GO:0051246 regulation of protein metabolic process 0.0223766752896087 2704 11 6 0.545454545454545 0.0022189349112426
GO:BP GO:0007163 establishment or maintenance of cell polarity 0.0225988002138275 220 23 3 0.130434782608696 0.0136363636363636
GO:BP GO:0002446 neutrophil mediated immunity 0.0235244470458985 497 22 4 0.181818181818182 0.00804828973843058
GO:BP GO:0042119 neutrophil activation 0.0236068952635364 498 22 4 0.181818181818182 0.00803212851405622
GO:BP GO:0048522 positive regulation of cellular process 0.024263853579186 5757 27 16 0.592592592592593 0.00277922529095015
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 0.024263853579186 192 56 4 0.0714285714285714 0.0208333333333333
GO:BP GO:0036230 granulocyte activation 0.024263853579186 504 22 4 0.181818181818182 0.00793650793650794
GO:BP GO:0044267 cellular protein metabolic process 0.0243315813189227 5229 77 34 0.441558441558442 0.00650219927328361
GO:BP GO:0007005 mitochondrion organization 0.0243315813189227 561 62 7 0.112903225806452 0.0124777183600713
GO:BP GO:0000278 mitotic cell cycle 0.0246153769585093 1059 34 7 0.205882352941176 0.00661000944287063
GO:BP GO:0030833 regulation of actin filament polymerization 0.0246153769585093 177 30 3 0.1 0.0169491525423729
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 0.024686287528683 2518 12 6 0.5 0.00238284352660842
GO:BP GO:0045185 maintenance of protein location 0.024686287528683 98 54 3 0.0555555555555556 0.0306122448979592
GO:BP GO:0030001 metal ion transport 0.02492834377467 514 11 3 0.272727272727273 0.00583657587548638
GO:BP GO:0051235 maintenance of location 0.0253947534291884 337 54 5 0.0925925925925926 0.0148367952522255
GO:BP GO:0019058 viral life cycle 0.0258500518075503 353 32 4 0.125 0.0113314447592068
GO:BP GO:0065008 regulation of biological quality 0.0259322191275723 4131 27 13 0.481481481481481 0.00314693778746066
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 0.0270372793007392 434 43 5 0.116279069767442 0.0115207373271889
GO:BP GO:0043299 leukocyte degranulation 0.0275471670956669 535 22 4 0.181818181818182 0.00747663551401869
GO:BP GO:0019222 regulation of metabolic process 0.0282293446565368 7148 6 6 1 0.000839395635142697
GO:BP GO:0042592 homeostatic process 0.0282293446565368 1981 7 4 0.571428571428571 0.00201918223119637
GO:BP GO:0002444 myeloid leukocyte mediated immunity 0.028577458629041 551 22 4 0.181818181818182 0.00725952813067151
GO:BP GO:0002275 myeloid cell activation involved in immune response 0.028577458629041 547 22 4 0.181818181818182 0.00731261425959781
GO:BP GO:0060047 heart contraction 0.028577458629041 288 41 4 0.0975609756097561 0.0138888888888889
GO:BP GO:0030041 actin filament polymerization 0.0290568502369977 196 30 3 0.1 0.0153061224489796
GO:BP GO:0072527 pyrimidine-containing compound metabolic process 0.0304956923233702 84 71 3 0.0422535211267606 0.0357142857142857
GO:BP GO:0034765 regulation of ion transmembrane transport 0.0310141409897908 583 11 3 0.272727272727273 0.00514579759862779
GO:BP GO:0003015 heart process 0.0310141409897908 298 41 4 0.0975609756097561 0.0134228187919463
GO:BP GO:0051098 regulation of binding 0.0311919093225739 365 54 5 0.0925925925925926 0.0136986301369863
GO:BP GO:0034762 regulation of transmembrane transport 0.0315489435751187 588 11 3 0.272727272727273 0.00510204081632653
GO:BP GO:0042775 mitochondrial ATP synthesis coupled electron transport 0.0319216276719252 99 62 3 0.0483870967741935 0.0303030303030303
GO:BP GO:0010563 negative regulation of phosphorus metabolic process 0.0320984184988463 544 12 3 0.25 0.00551470588235294
GO:BP GO:0045936 negative regulation of phosphate metabolic process 0.0320984184988463 543 12 3 0.25 0.00552486187845304
GO:BP GO:0009142 nucleoside triphosphate biosynthetic process 0.0320984184988463 87 71 3 0.0422535211267606 0.0344827586206897
GO:BP GO:0051701 biological process involved in interaction with host 0.0320984184988463 221 56 4 0.0714285714285714 0.0180995475113122
GO:BP GO:0002252 immune effector process 0.032168732291391 1309 23 6 0.260869565217391 0.00458365164247517
GO:BP GO:0042773 ATP synthesis coupled electron transport 0.032168732291391 100 62 3 0.0483870967741935 0.03
GO:BP GO:0034641 cellular nitrogen compound metabolic process 0.0328792321876006 6563 83 42 0.506024096385542 0.00639951241810148
GO:BP GO:0016197 endosomal transport 0.0328792321876006 246 51 4 0.0784313725490196 0.016260162601626
GO:BP GO:0009628 response to abiotic stimulus 0.0333278998946405 1261 11 4 0.363636363636364 0.00317208564631245
GO:BP GO:0006974 cellular response to DNA damage stimulus 0.0334526587761376 888 67 9 0.134328358208955 0.0101351351351351
GO:BP GO:0045321 leukocyte activation 0.0338515534832787 1332 23 6 0.260869565217391 0.0045045045045045
GO:BP GO:0031323 regulation of cellular metabolic process 0.0341606777234589 6269 51 27 0.529411764705882 0.00430690700271176
GO:BP GO:0009058 biosynthetic process 0.0344415230088306 6340 74 37 0.5 0.00583596214511041
GO:BP GO:0051101 regulation of DNA binding 0.034769967174031 121 54 3 0.0555555555555556 0.0247933884297521
GO:BP GO:0006955 immune response 0.0350819823034226 2311 23 8 0.347826086956522 0.00346170488965816
GO:BP GO:0030036 actin cytoskeleton organization 0.0350819823034226 709 30 5 0.166666666666667 0.00705218617771509
GO:BP GO:0050684 regulation of mRNA processing 0.0350819823034226 158 82 4 0.0487804878048781 0.0253164556962025
GO:BP GO:0019882 antigen processing and presentation 0.035595911967315 234 56 4 0.0714285714285714 0.0170940170940171
GO:BP GO:0010498 proteasomal protein catabolic process 0.035595911967315 491 43 5 0.116279069767442 0.010183299389002
GO:BP GO:0043484 regulation of RNA splicing 0.0358617031760707 160 82 4 0.0487804878048781 0.025
GO:BP GO:0090150 establishment of protein localization to membrane 0.0359837709415543 351 60 5 0.0833333333333333 0.0142450142450142
GO:BP GO:0120031 plasma membrane bounded cell projection assembly 0.0362385755835863 593 23 4 0.173913043478261 0.00674536256323777
GO:BP GO:0044249 cellular biosynthetic process 0.0367014344922689 6154 74 36 0.486486486486487 0.00584985375365616
GO:BP GO:0048523 negative regulation of cellular process 0.0377771808621805 5139 12 8 0.666666666666667 0.00155672309787896
GO:BP GO:0030031 cell projection assembly 0.0381367292242592 607 23 4 0.173913043478261 0.00658978583196046
GO:BP GO:0032271 regulation of protein polymerization 0.0388444704876206 236 30 3 0.1 0.0127118644067797
GO:BP GO:0071702 organic substance transport 0.0393190108215007 2766 60 17 0.283333333333333 0.00614605929139552
GO:BP GO:0006518 peptide metabolic process 0.0394106687860155 955 77 10 0.12987012987013 0.0104712041884817
GO:BP GO:0072655 establishment of protein localization to mitochondrion 0.0395847829723793 143 50 3 0.06 0.020979020979021
GO:BP GO:0051403 stress-activated MAPK cascade 0.0395847829723793 272 80 5 0.0625 0.0183823529411765
GO:BP GO:0050776 regulation of immune response 0.0395867438996088 996 23 5 0.217391304347826 0.00502008032128514
GO:BP GO:0044260 cellular macromolecule metabolic process 0.0397829946467079 8390 83 50 0.602409638554217 0.00595947556615018
GO:BP GO:0034220 ion transmembrane transport 0.0401720835825438 1397 11 4 0.363636363636364 0.00286327845382963
GO:BP GO:0022904 respiratory electron transport chain 0.0403355012804057 117 62 3 0.0483870967741935 0.0256410256410256
GO:BP GO:0070585 protein localization to mitochondrion 0.0407979753940751 147 50 3 0.06 0.0204081632653061
GO:BP GO:0002274 myeloid leukocyte activation 0.0407979753940751 667 22 4 0.181818181818182 0.00599700149925037
GO:BP GO:0006839 mitochondrial transport 0.0407979753940751 284 50 4 0.08 0.0140845070422535
GO:BP GO:0046887 positive regulation of hormone secretion 0.0416855841895808 133 56 3 0.0535714285714286 0.0225563909774436
GO:BP GO:0007010 cytoskeleton organization 0.0427007442498399 1423 38 8 0.210526315789474 0.005621925509487
GO:BP GO:0002181 cytoplasmic translation 0.0427683943164301 103 73 3 0.0410958904109589 0.029126213592233
GO:BP GO:0007006 mitochondrial membrane organization 0.0428385560230968 151 50 3 0.06 0.0198675496688742
GO:BP GO:0043433 negative regulation of DNA-binding transcription factor activity 0.0439508210262561 187 41 3 0.0731707317073171 0.0160427807486631
GO:BP GO:0048518 positive regulation of biological process 0.0443037779667831 6363 27 16 0.592592592592593 0.00251453716800251
GO:BP GO:0031098 stress-activated protein kinase signaling cascade 0.0443109225367527 288 80 5 0.0625 0.0173611111111111
GO:BP GO:0051179 localization 0.0443109225367527 6901 57 31 0.543859649122807 0.00449210259382698
GO:BP GO:0030162 regulation of proteolysis 0.0449899079606807 752 11 3 0.272727272727273 0.00398936170212766
GO:BP GO:0001775 cell activation 0.0451885191110194 1495 23 6 0.260869565217391 0.0040133779264214
GO:BP GO:0046718 viral entry into host cell 0.0452246704437465 141 56 3 0.0535714285714286 0.0212765957446809
GO:BP GO:0019538 protein metabolic process 0.0452246704437465 5808 77 35 0.454545454545455 0.00602617079889807
GO:BP GO:0007265 Ras protein signal transduction 0.0452246704437465 349 23 3 0.130434782608696 0.00859598853868195
GO:BP GO:0007346 regulation of mitotic cell cycle 0.0457561604467524 619 25 4 0.16 0.00646203554119548
GO:BP GO:0009141 nucleoside triphosphate metabolic process 0.046184045571683 113 71 3 0.0422535211267606 0.0265486725663717
GO:BP GO:0002366 leukocyte activation involved in immune response 0.0464819727012834 717 22 4 0.181818181818182 0.00557880055788006
GO:BP GO:0045055 regulated exocytosis 0.0468226119448414 785 56 7 0.125 0.0089171974522293
GO:BP GO:0006807 nitrogen compound metabolic process 0.0468819774590971 10078 83 57 0.686746987951807 0.00565588410398889
GO:BP GO:0002263 cell activation involved in immune response 0.0468819774590971 721 22 4 0.181818181818182 0.00554785020804438
GO:BP GO:0065009 regulation of molecular function 0.0471253809072354 3221 26 10 0.384615384615385 0.00310462589257994
GO:BP GO:0044093 positive regulation of molecular function 0.0472656367663511 1771 26 7 0.269230769230769 0.00395256916996047
GO:BP GO:0006820 anion transport 0.0477630988898688 2889 60 17 0.283333333333333 0.00588438906195916
GO:BP GO:0034504 protein localization to nucleus 0.0477630988898688 289 54 4 0.0740740740740741 0.013840830449827
GO:BP GO:0090407 organophosphate biosynthetic process 0.0482566547945491 598 74 7 0.0945945945945946 0.0117056856187291
GO:BP GO:0051347 positive regulation of transferase activity 0.0482566547945491 689 80 8 0.1 0.011611030478955
GO:BP GO:0032879 regulation of localization 0.0489139393434848 2872 56 16 0.285714285714286 0.00557103064066852
GO:BP GO:0006396 RNA processing 0.0492054623989544 964 82 10 0.121951219512195 0.0103734439834025
GO:BP GO:0044238 primary metabolic process 0.0493249885113052 10584 83 59 0.710843373493976 0.00557445200302343
GO:BP GO:0010564 regulation of cell cycle process 0.0493249885113052 809 43 6 0.13953488372093 0.00741656365883807
GO:BP GO:0007049 cell cycle 0.0497880620380222 1902 43 10 0.232558139534884 0.00525762355415352
GO:BP GO:0044772 mitotic cell cycle phase transition 0.0497880620380222 609 57 6 0.105263157894737 0.00985221674876847
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0497880620380222 2541 11 5 0.454545454545455 0.00196772924045651
GO:BP GO:0044092 negative regulation of molecular function 0.0497880620380222 1219 14 4 0.285714285714286 0.00328137817883511
GO:BP GO:0055085 transmembrane transport 0.0497880620380222 1635 6 3 0.5 0.0018348623853211
GO:BP GO:0044409 entry into host 0.0499227311038257 154 56 3 0.0535714285714286 0.0194805194805195
GO:CC GO:0032991 protein-containing complex 3.91881095773102e-05 5548 82 47 0.573170731707317 0.00847152126892574
GO:CC GO:0005829 cytosol 0.00162671419361344 5303 80 41 0.5125 0.00773147275127286
GO:CC GO:0070062 extracellular exosome 0.00302885168628649 2176 56 18 0.321428571428571 0.00827205882352941
GO:CC GO:0043230 extracellular organelle 0.00302885168628649 2263 56 18 0.321428571428571 0.00795404330534688
GO:CC GO:1903561 extracellular vesicle 0.00302885168628649 2261 56 18 0.321428571428571 0.00796107916850951
GO:CC GO:0101002 ficolin-1-rich granule 0.00302885168628649 184 22 4 0.181818181818182 0.0217391304347826
GO:CC GO:0140513 nuclear protein-containing complex 0.00302885168628649 1249 72 15 0.208333333333333 0.0120096076861489
GO:CC GO:1902494 catalytic complex 0.00306526630563363 1441 71 16 0.225352112676056 0.0111034004163775
GO:CC GO:1990904 ribonucleoprotein complex 0.00586780724612297 688 81 11 0.135802469135802 0.0159883720930233
GO:CC GO:0045335 phagocytic vesicle 0.00586780724612297 137 70 5 0.0714285714285714 0.0364963503649635
GO:CC GO:0043227 membrane-bounded organelle 0.00620709566162393 12858 83 71 0.855421686746988 0.00552185409861565
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.0066832865391438 11296 83 65 0.783132530120482 0.0057542492917847
GO:CC GO:0005622 intracellular anatomical structure 0.00730166294553058 14790 83 77 0.927710843373494 0.00520622041920216
GO:CC GO:1904813 ficolin-1-rich granule lumen 0.00941936179433155 124 22 3 0.136363636363636 0.0241935483870968
GO:CC GO:0005737 cytoplasm 0.0101163333051988 11911 78 63 0.807692307692308 0.00528922844429519
GO:CC GO:0098796 membrane protein complex 0.0101163333051988 1322 16 6 0.375 0.00453857791225416
GO:CC GO:0099503 secretory vesicle 0.0108674784116646 1020 56 10 0.178571428571429 0.00980392156862745
GO:CC GO:0005875 microtubule associated complex 0.0108674784116646 165 20 3 0.15 0.0181818181818182
GO:CC GO:0031982 vesicle 0.0108674784116646 4055 56 23 0.410714285714286 0.00567200986436498
GO:CC GO:0030141 secretory granule 0.0113943551418764 851 56 9 0.160714285714286 0.0105757931844888
GO:CC GO:0043229 intracellular organelle 0.0122978958951144 12491 83 68 0.819277108433735 0.00544391962212793
GO:CC GO:0030426 growth cone 0.0160697200335007 187 22 3 0.136363636363636 0.0160427807486631
GO:CC GO:0030427 site of polarized growth 0.0161658727974069 193 22 3 0.136363636363636 0.0155440414507772
GO:CC GO:0031252 cell leading edge 0.0161658727974069 422 23 4 0.173913043478261 0.00947867298578199
GO:CC GO:0030027 lamellipodium 0.0161658727974069 200 22 3 0.136363636363636 0.015
GO:CC GO:0005925 focal adhesion 0.0196244355854445 420 60 6 0.1 0.0142857142857143
GO:CC GO:0140535 intracellular protein-containing complex 0.0200987617675598 767 71 9 0.126760563380282 0.0117340286831812
GO:CC GO:0030055 cell-substrate junction 0.0202773151718094 427 60 6 0.1 0.0140515222482436
GO:CC GO:0005746 mitochondrial respirasome 0.0237369079106728 89 62 3 0.0483870967741935 0.0337078651685393
GO:CC GO:0005739 mitochondrion 0.0237369079106728 1673 78 15 0.192307692307692 0.00896592946802152
GO:CC GO:0005634 nucleus 0.0241307773439655 7592 83 46 0.55421686746988 0.00605900948366702
GO:CC GO:0035770 ribonucleoprotein granule 0.0241307773439655 248 47 4 0.0851063829787234 0.0161290322580645
GO:CC GO:0005773 vacuole 0.024327476183195 810 8 3 0.375 0.0037037037037037
GO:CC GO:0043226 organelle 0.024327476183195 14008 83 72 0.867469879518072 0.00513992004568818
GO:CC GO:0150034 distal axon 0.025578856065912 308 41 4 0.0975609756097561 0.012987012987013
GO:CC GO:0043197 dendritic spine 0.0256208707323681 183 69 4 0.0579710144927536 0.0218579234972678
GO:CC GO:0044309 neuron spine 0.0256392250404615 185 69 4 0.0579710144927536 0.0216216216216216
GO:CC GO:0070469 respirasome 0.0256392250404615 103 62 3 0.0483870967741935 0.029126213592233
GO:CC GO:0043005 neuron projection 0.0273679528898148 1380 23 6 0.260869565217391 0.00434782608695652
GO:CC GO:0098588 bounding membrane of organelle 0.0286655829701796 2158 4 3 0.75 0.00139017608897127
GO:CC GO:0030139 endocytic vesicle 0.0286655829701796 306 70 5 0.0714285714285714 0.0163398692810458
GO:CC GO:0097708 intracellular vesicle 0.0293152935439294 2428 23 8 0.347826086956522 0.00329489291598023
GO:CC GO:0031410 cytoplasmic vesicle 0.0293152935439294 2424 23 8 0.347826086956522 0.0033003300330033
GO:CC GO:0005654 nucleoplasm 0.029781720368236 4102 82 28 0.341463414634146 0.0068259385665529
GO:CC GO:0030424 axon 0.030855893725067 660 22 4 0.181818181818182 0.00606060606060606
GO:CC GO:0043233 organelle lumen 0.0318609904755537 5565 82 35 0.426829268292683 0.00628930817610063
GO:CC GO:0031974 membrane-enclosed lumen 0.0318609904755537 5565 82 35 0.426829268292683 0.00628930817610063
GO:CC GO:0016604 nuclear body 0.032898295823752 816 29 5 0.172413793103448 0.00612745098039216
GO:CC GO:1990234 transferase complex 0.0345123753022616 804 82 9 0.109756097560976 0.0111940298507463
GO:CC GO:0005615 extracellular space 0.0345123753022616 3594 42 15 0.357142857142857 0.00417362270450751
GO:CC GO:0005681 spliceosomal complex 0.0373863284969985 191 81 4 0.0493827160493827 0.0209424083769634
GO:CC GO:0031981 nuclear lumen 0.0393916013259697 4444 82 29 0.353658536585366 0.00652565256525653
GO:CC GO:0005819 spindle 0.0427531733601123 387 23 3 0.130434782608696 0.00775193798449612
GO:CC GO:0012505 endomembrane system 0.0456103002144214 4640 12 7 0.583333333333333 0.00150862068965517
GO:CC GO:0120025 plasma membrane bounded cell projection 0.0471706764858791 2229 23 7 0.304347826086957 0.00314042171377299
GO:CC GO:0099080 supramolecular complex 0.049224943492143 1323 47 8 0.170212765957447 0.00604686318972033
GO:CC GO:0031090 organelle membrane 0.0494393074719255 3612 12 6 0.5 0.00166112956810631
GO:MF GO:0044877 protein-containing complex binding 0.00122795933980607 1287 31 11 0.354838709677419 0.00854700854700855
GO:MF GO:0003723 RNA binding 0.0122986048524533 1943 61 17 0.278688524590164 0.00874935666495111
GO:MF GO:0003743 translation initiation factor activity 0.0169890159538883 58 48 3 0.0625 0.0517241379310345
GO:MF GO:0044325 ion channel binding 0.0169890159538883 135 50 4 0.08 0.0296296296296296
GO:MF GO:0097110 scaffold protein binding 0.0169890159538883 59 38 3 0.0789473684210526 0.0508474576271186
GO:MF GO:0099106 ion channel regulator activity 0.0169890159538883 120 56 4 0.0714285714285714 0.0333333333333333
GO:MF GO:0090079 translation regulator activity, nucleic acid binding 0.0169890159538883 123 48 4 0.0833333333333333 0.032520325203252
GO:MF GO:0031625 ubiquitin protein ligase binding 0.0192662292758331 296 11 3 0.272727272727273 0.0101351351351351
GO:MF GO:0045182 translation regulator activity 0.0192662292758331 155 48 4 0.0833333333333333 0.0258064516129032
GO:MF GO:0044389 ubiquitin-like protein ligase binding 0.0192662292758331 314 11 3 0.272727272727273 0.00955414012738853
GO:MF GO:0019899 enzyme binding 0.0223178424417317 2074 12 6 0.5 0.00289296046287367
GO:MF GO:0016247 channel regulator activity 0.022714391452923 149 56 4 0.0714285714285714 0.0268456375838926
GO:MF GO:0008135 translation factor activity, RNA binding 0.0265067922697169 99 48 3 0.0625 0.0303030303030303
GO:MF GO:0008134 transcription factor binding 0.0265067922697169 676 18 4 0.222222222222222 0.00591715976331361
GO:MF GO:0005515 protein binding 0.0265067922697169 14767 76 70 0.921052631578947 0.00474029931604253
GO:MF GO:0016651 oxidoreductase activity, acting on NAD(P)H 0.0267685187445156 107 54 3 0.0555555555555556 0.0280373831775701
GO:MF GO:0051015 actin filament binding 0.0289960593464102 212 30 3 0.1 0.0141509433962264
GO:MF GO:0043021 ribonucleoprotein complex binding 0.0301361758170424 137 48 3 0.0625 0.0218978102189781
GO:MF GO:0019904 protein domain specific binding 0.0392290712910611 710 50 6 0.12 0.00845070422535211
GO:MF GO:0047485 protein N-terminus binding 0.0408778736464534 111 80 3 0.0375 0.027027027027027
GO:MF GO:0009055 electron transfer activity 0.0431484719738978 148 62 3 0.0483870967741935 0.0202702702702703
GO:MF GO:0140297 DNA-binding transcription factor binding 0.0444448713738763 391 68 5 0.0735294117647059 0.0127877237851662
GO:MF GO:0001883 purine nucleoside binding 0.0479743937254087 389 70 5 0.0714285714285714 0.012853470437018
KEGG KEGG:03013 RNA transport 0.0101363444089393 180 49 7 0.142857142857143 0.0388888888888889
KEGG KEGG:05132 Salmonella infection 0.0300830316902781 249 23 5 0.217391304347826 0.0200803212851406
MIRNA MIRNA:hsa-miR-4496 hsa-miR-4496 0.000113657706956195 118 15 5 0.333333333333333 0.0423728813559322
MIRNA MIRNA:hsa-miR-4495 hsa-miR-4495 0.0065793351679959 126 37 5 0.135135135135135 0.0396825396825397
MIRNA MIRNA:hsa-miR-32-3p hsa-miR-32-3p 0.0065793351679959 123 6 3 0.5 0.024390243902439
MIRNA MIRNA:hsa-miR-548at-5p hsa-miR-548at-5p 0.0212299371988837 122 83 6 0.072289156626506 0.0491803278688525
MIRNA MIRNA:hsa-miR-2054 hsa-miR-2054 0.0251473724889385 75 47 4 0.0851063829787234 0.0533333333333333
MIRNA MIRNA:hsa-miR-133a-3p hsa-miR-133a-3p 0.0264340131000073 129 34 4 0.117647058823529 0.0310077519379845
MIRNA MIRNA:hsa-miR-513c-3p hsa-miR-513c-3p 0.0264340131000073 185 11 3 0.272727272727273 0.0162162162162162
MIRNA MIRNA:hsa-miR-10b-3p hsa-miR-10b-3p 0.0264340131000073 82 20 3 0.15 0.0365853658536585
MIRNA MIRNA:hsa-miR-653-5p hsa-miR-653-5p 0.0264340131000073 76 24 3 0.125 0.0394736842105263
MIRNA MIRNA:hsa-miR-4445-5p hsa-miR-4445-5p 0.0264340131000073 50 37 3 0.0810810810810811 0.06
MIRNA MIRNA:hsa-miR-3925-5p hsa-miR-3925-5p 0.0264340131000073 115 15 3 0.2 0.0260869565217391
MIRNA MIRNA:hsa-miR-3606-3p hsa-miR-3606-3p 0.0264340131000073 188 11 3 0.272727272727273 0.0159574468085106
MIRNA MIRNA:hsa-miR-3688-3p hsa-miR-3688-3p 0.0264340131000073 114 72 5 0.0694444444444444 0.043859649122807
MIRNA MIRNA:hsa-miR-5093 hsa-miR-5093 0.0264340131000073 118 15 3 0.2 0.0254237288135593
MIRNA MIRNA:hsa-miR-513a-3p hsa-miR-513a-3p 0.0264340131000073 187 11 3 0.272727272727273 0.0160427807486631
MIRNA MIRNA:hsa-miR-1250-3p hsa-miR-1250-3p 0.0280334242005551 204 45 5 0.111111111111111 0.0245098039215686
MIRNA MIRNA:hsa-miR-8071 hsa-miR-8071 0.0280334242005551 87 24 3 0.125 0.0344827586206897
MIRNA MIRNA:hsa-miR-5700 hsa-miR-5700 0.0293191132391906 89 67 4 0.0597014925373134 0.0449438202247191
MIRNA MIRNA:hsa-miR-374a-5p hsa-miR-374a-5p 0.0293191132391906 282 10 3 0.3 0.0106382978723404
MIRNA MIRNA:hsa-miR-4795-5p hsa-miR-4795-5p 0.0293191132391906 151 35 4 0.114285714285714 0.0264900662251656
MIRNA MIRNA:hsa-miR-548n hsa-miR-548n 0.0293191132391906 259 83 7 0.0843373493975904 0.027027027027027
MIRNA MIRNA:hsa-miR-3662 hsa-miR-3662 0.0293191132391906 252 10 3 0.3 0.0119047619047619
MIRNA MIRNA:hsa-miR-423-5p hsa-miR-423-5p 0.0293191132391906 342 47 6 0.127659574468085 0.0175438596491228
MIRNA MIRNA:hsa-miR-26b-5p hsa-miR-26b-5p 0.0293191132391906 1852 40 13 0.325 0.00701943844492441
MIRNA MIRNA:hsa-miR-6878-5p hsa-miR-6878-5p 0.0293191132391906 248 24 4 0.166666666666667 0.0161290322580645
MIRNA MIRNA:hsa-miR-152-5p hsa-miR-152-5p 0.0293191132391906 50 51 3 0.0588235294117647 0.06
MIRNA MIRNA:hsa-miR-4504 hsa-miR-4504 0.0293191132391906 70 82 4 0.0487804878048781 0.0571428571428571
MIRNA MIRNA:hsa-miR-129-5p hsa-miR-129-5p 0.0293191132391906 621 45 8 0.177777777777778 0.0128824476650564
MIRNA MIRNA:hsa-miR-380-3p hsa-miR-380-3p 0.0293191132391906 76 30 3 0.1 0.0394736842105263
MIRNA MIRNA:hsa-miR-889-5p hsa-miR-889-5p 0.029674993340921 51 54 3 0.0555555555555556 0.0588235294117647
MIRNA MIRNA:hsa-miR-133b hsa-miR-133b 0.0299961662495999 83 34 3 0.0882352941176471 0.036144578313253
MIRNA MIRNA:hsa-miR-6825-5p hsa-miR-6825-5p 0.031282167190256 380 18 4 0.222222222222222 0.0105263157894737
MIRNA MIRNA:hsa-miR-374b-5p hsa-miR-374b-5p 0.0317758929590397 234 49 5 0.102040816326531 0.0213675213675214
MIRNA MIRNA:hsa-miR-548o-3p hsa-miR-548o-3p 0.0332744475161841 118 57 4 0.0701754385964912 0.0338983050847458
MIRNA MIRNA:hsa-miR-1323 hsa-miR-1323 0.0339102282652221 120 57 4 0.0701754385964912 0.0333333333333333
MIRNA MIRNA:hsa-miR-548k hsa-miR-548k 0.0375233013117105 147 50 4 0.08 0.0272108843537415
MIRNA MIRNA:hsa-miR-548av-5p hsa-miR-548av-5p 0.0375233013117105 147 50 4 0.08 0.0272108843537415
MIRNA MIRNA:hsa-miR-8054 hsa-miR-8054 0.0375233013117105 147 50 4 0.08 0.0272108843537415
MIRNA MIRNA:hsa-miR-1226-3p hsa-miR-1226-3p 0.0395554292470381 226 83 6 0.072289156626506 0.0265486725663717
MIRNA MIRNA:hsa-miR-484 hsa-miR-484 0.0435625748237124 890 39 8 0.205128205128205 0.00898876404494382
MIRNA MIRNA:hsa-miR-6854-5p hsa-miR-6854-5p 0.0456377673588751 81 47 3 0.0638297872340425 0.037037037037037
MIRNA MIRNA:hsa-miR-4483 hsa-miR-4483 0.0456377673588751 131 30 3 0.1 0.0229007633587786
MIRNA MIRNA:hsa-miR-15b-5p hsa-miR-15b-5p 0.0456377673588751 760 57 9 0.157894736842105 0.0118421052631579
MIRNA MIRNA:hsa-miR-4717-3p hsa-miR-4717-3p 0.0456377673588751 78 50 3 0.06 0.0384615384615385
MIRNA MIRNA:hsa-miR-1293 hsa-miR-1293 0.0473649374425824 134 30 3 0.1 0.0223880597014925
MIRNA MIRNA:hsa-miR-493-3p hsa-miR-493-3p 0.0483057935860298 87 47 3 0.0638297872340425 0.0344827586206897
MIRNA MIRNA:hsa-miR-1303 hsa-miR-1303 0.0483057935860298 199 71 5 0.0704225352112676 0.0251256281407035
MIRNA MIRNA:hsa-miR-6835-3p hsa-miR-6835-3p 0.0483057935860298 137 62 4 0.0645161290322581 0.0291970802919708
MIRNA MIRNA:hsa-miR-544b hsa-miR-544b 0.0487003817873943 202 43 4 0.0930232558139535 0.0198019801980198
REAC REAC:R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 0.00538825170388771 35 23 3 0.130434782608696 0.0857142857142857
REAC REAC:R-HSA-5696398 Nucleotide Excision Repair 0.0113312858420143 109 11 3 0.272727272727273 0.0275229357798165
REAC REAC:R-HSA-5663205 Infectious disease 0.0151122813170274 815 43 11 0.255813953488372 0.0134969325153374
REAC REAC:R-HSA-195258 RHO GTPase Effectors 0.0151122813170274 283 23 5 0.217391304347826 0.0176678445229682
REAC REAC:R-HSA-114452 Activation of BH3-only proteins 0.0160790319244209 30 50 3 0.06 0.1
REAC REAC:R-HSA-199991 Membrane Trafficking 0.0162890730064827 625 75 13 0.173333333333333 0.0208
REAC REAC:R-HSA-5696395 Formation of Incision Complex in GG-NER 0.0162890730064827 43 37 3 0.0810810810810811 0.0697674418604651
REAC REAC:R-HSA-4570464 SUMOylation of RNA binding proteins 0.0165105059864324 43 39 3 0.0769230769230769 0.0697674418604651
REAC REAC:R-HSA-194315 Signaling by Rho GTPases 0.0269559887743398 413 23 5 0.217391304347826 0.0121065375302663
REAC REAC:R-HSA-5628897 TP53 Regulates Metabolic Genes 0.0269559887743398 83 62 4 0.0645161290322581 0.0481927710843374
REAC REAC:R-HSA-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 0.0269559887743398 413 23 5 0.217391304347826 0.0121065375302663
REAC REAC:R-HSA-9664422 FCGR3A-mediated phagocytosis 0.0269559887743398 113 23 3 0.130434782608696 0.0265486725663717
REAC REAC:R-HSA-9664407 Parasite infection 0.0269559887743398 113 23 3 0.130434782608696 0.0265486725663717
REAC REAC:R-HSA-9664417 Leishmania phagocytosis 0.0269559887743398 113 23 3 0.130434782608696 0.0265486725663717
REAC REAC:R-HSA-5653656 Vesicle-mediated transport 0.0269559887743398 717 57 11 0.192982456140351 0.0153417015341702
REAC REAC:R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 0.0281761462881914 116 23 3 0.130434782608696 0.0258620689655172
REAC REAC:R-HSA-199977 ER to Golgi Anterograde Transport 0.0320160410894809 154 69 5 0.072463768115942 0.0324675324675325
REAC REAC:R-HSA-69620 Cell Cycle Checkpoints 0.0320160410894809 271 12 3 0.25 0.011070110701107
REAC REAC:R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 0.0320160410894809 84 37 3 0.0810810810810811 0.0357142857142857
REAC REAC:R-HSA-73894 DNA Repair 0.0320160410894809 303 11 3 0.272727272727273 0.0099009900990099
REAC REAC:R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 0.0320160410894809 140 23 3 0.130434782608696 0.0214285714285714
REAC REAC:R-HSA-168249 Innate Immune System 0.0320160410894809 1073 56 13 0.232142857142857 0.0121155638397018
REAC REAC:R-HSA-170834 Signaling by TGF-beta Receptor Complex 0.0366423606406563 71 49 3 0.0612244897959184 0.0422535211267606
REAC REAC:R-HSA-432722 Golgi Associated Vesicle Biogenesis 0.0483354267620899 54 75 3 0.04 0.0555555555555556
REAC REAC:R-HSA-948021 Transport to the Golgi and subsequent modification 0.0499750070776513 185 69 5 0.072463768115942 0.027027027027027
TF TF:M04694 Factor: NRF-1; motif: CNCTGCGCATGCGC 4.79581294682704e-07 1548 83 27 0.325301204819277 0.0174418604651163
TF TF:M10018 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS 1.6532331339791e-06 1816 83 28 0.337349397590361 0.0154185022026432
TF TF:M07052 Factor: NRF-1; motif: GCGCMTGCGCN 8.75084225057423e-06 2130 83 29 0.349397590361446 0.0136150234741784
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 6.37853894928624e-05 9423 83 64 0.771084337349398 0.00679189217871166
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 6.4238107795896e-05 11728 83 72 0.867469879518072 0.00613915416098226
TF TF:M08390_1 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA; match class: 1 0.000173119341959887 4784 57 32 0.56140350877193 0.00668896321070234
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.000173119341959887 8056 77 54 0.701298701298701 0.00670307845084409
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.000173119341959887 11116 83 69 0.831325301204819 0.00620726880172724
TF TF:M09641 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN 0.000173119341959887 3222 79 32 0.40506329113924 0.00993171942892613
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.000299966107952268 10107 82 64 0.780487804878049 0.00633224497872761
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.000445673349501509 8322 83 57 0.686746987951807 0.00684931506849315
TF TF:M11382 Factor: ESE-1; motif: NWTRCGGAWGCN 0.000445673349501509 10339 83 65 0.783132530120482 0.00628687493954928
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.000445673349501509 7045 82 51 0.621951219512195 0.00723917672107878
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.000466843355956034 6749 83 50 0.602409638554217 0.00740850496369833
TF TF:M11422 Factor: Erm; motif: NRCMGGAAGTN 0.000466843355956034 4669 75 37 0.493333333333333 0.00792460912400942
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.000563614806774337 15268 83 80 0.963855421686747 0.00523971705527901
TF TF:M08457_1 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY; match class: 1 0.000620144803043722 5591 45 28 0.622222222222222 0.00500804864961545
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.000620144803043722 10262 83 64 0.771084337349398 0.00623660105242643
TF TF:M09606 Factor: nerf; motif: NRRNSCGGAAGNRNNNN 0.000620144803043722 6249 69 41 0.594202898550725 0.00656104976796287
TF TF:M04059 Factor: NRF-1; motif: YGCGCATGCGCN 0.000620144803043722 1471 83 20 0.240963855421687 0.0135961930659415
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.000620144803043722 9474 83 61 0.734939759036145 0.00643867426641334
TF TF:M04950 Factor: Egr-1; motif: NGCGTGCGY 0.000620144803043722 10935 55 47 0.854545454545454 0.00429812528577961
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 0.000623388458167146 13929 60 57 0.95 0.00409218177902218
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.000824172962767047 8690 77 54 0.701298701298701 0.00621403912543153
TF TF:M11432 Factor: Elk-1; motif: NACMGGAAGTN 0.000910362017145504 6140 76 43 0.565789473684211 0.00700325732899023
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.00120297620762002 8219 83 55 0.662650602409639 0.00669181165591921
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.00126341110565464 10765 77 61 0.792207792207792 0.00566651184393869
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.00126341110565464 8318 77 52 0.675324675324675 0.00625150276508776
TF TF:M09894 Factor: E2F-4; motif: SNGGGCGGGAANN 0.00126341110565464 16194 61 61 1 0.00376682721995801
TF TF:M02102 Factor: NRF-1; motif: YGCGCMTGCGC 0.00129162273511536 2020 83 23 0.27710843373494 0.0113861386138614
TF TF:M11400 Factor: Fli-1; motif: NACCGGAARTN 0.00129718874191678 9946 77 58 0.753246753246753 0.00583149004624975
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.00130813666687732 15260 46 46 1 0.00301441677588467
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.00130813666687732 14473 83 77 0.927710843373494 0.00532025150279831
TF TF:M09971 Factor: GKLF; motif: WGGGYGKGGC 0.00130813666687732 5546 45 27 0.6 0.00486837360259647
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.00130813666687732 10837 83 65 0.783132530120482 0.00599796991787395
TF TF:M09935 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN 0.00130813666687732 4420 32 19 0.59375 0.00429864253393665
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.00131648766149924 12550 83 71 0.855421686746988 0.00565737051792829
TF TF:M00360 Factor: Pax-3; motif: TCGTCACRCTTHM 0.00135530381263368 12238 71 61 0.859154929577465 0.00498447458735087
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.00141327396655199 2702 74 25 0.337837837837838 0.00925240562546262
TF TF:M04714 Factor: Elf-1; motif: ACTTCCGGG 0.00156350727316948 7798 82 52 0.634146341463415 0.00666837650679661
TF TF:M01163 Factor: Elk-1; motif: AACCGGAAGTR 0.00172057733915543 5260 76 38 0.5 0.00722433460076046
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.00172057733915543 8743 77 53 0.688311688311688 0.00606199245110374
TF TF:M07039_1 Factor: ETF; motif: CCCCGCCCCYN; match class: 1 0.00235015399884027 13611 56 52 0.928571428571429 0.00382043935052531
TF TF:M00678 Factor: Tel-2; motif: YTACTTCCTG 0.0023588903723465 5292 56 30 0.535714285714286 0.00566893424036281
TF TF:M08878 Factor: EGR; motif: CGCCCCCGCNN 0.0023588903723465 7483 58 38 0.655172413793103 0.00507817720165709
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.0023588903723465 15072 60 58 0.966666666666667 0.00384819532908705
TF TF:M11447 Factor: Elf-1; motif: NAMCCGGAAGTN 0.0023588903723465 7703 82 51 0.621951219512195 0.00662079709204206
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 0.0023588903723465 16263 83 81 0.975903614457831 0.00498063087991146
TF TF:M04950_1 Factor: Egr-1; motif: NGCGTGCGY; match class: 1 0.0023588903723465 5551 49 28 0.571428571428571 0.00504413619167718
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.0023588903723465 7600 83 51 0.614457831325301 0.00671052631578947
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.0023588903723465 10116 76 57 0.75 0.00563463819691578
TF TF:M03967 Factor: ELF3; motif: WACCCGGAAGTAN 0.00236161967606711 7610 83 51 0.614457831325301 0.00670170827858081
TF TF:M08759_1 Factor: c-Ets-2; motif: NCCGGAAGTG; match class: 1 0.00240904847169344 2915 40 17 0.425 0.00583190394511149
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.00240904847169344 5332 74 37 0.5 0.00693923480870218
TF TF:M09608 Factor: Erg; motif: NNACCGGAARTSN 0.00258759572089028 8152 77 50 0.649350649350649 0.00613346418056919
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.00258759572089028 10002 77 57 0.74025974025974 0.00569886022795441
TF TF:M11433 Factor: Elk-1; motif: NRCCGGAAGTN 0.00258759572089028 7679 65 42 0.646153846153846 0.00546946216955333
TF TF:M07206_1 Factor: E2F-1; motif: NGGGCGGGARV; match class: 1 0.00258759572089028 10849 52 43 0.826923076923077 0.00396349893999447
TF TF:M11485 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.00264877276524433 6977 16 14 0.875 0.00200659309158664
TF TF:M11425 Factor: PEA3; motif: NACCGGAAGTN 0.00285335589060048 7428 65 41 0.630769230769231 0.00551965535810447
TF TF:M03966 Factor: ELF1; motif: AACCCGGAAGTR 0.0028572382374251 6610 67 39 0.582089552238806 0.00590015128593041
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.00304298742562768 7600 82 50 0.609756097560976 0.00657894736842105
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.00304298742562768 14873 55 53 0.963636363636364 0.00356350433671754
TF TF:M02044_1 Factor: YY1; motif: GCCGCCATTTTG; match class: 1 0.00310877234317638 1198 83 16 0.192771084337349 0.013355592654424
TF TF:M08759 Factor: c-Ets-2; motif: NCCGGAAGTG 0.00310877234317638 8319 82 53 0.646341463414634 0.00637095804784229
TF TF:M04810_1 Factor: USF2; motif: AAGTCACG; match class: 1 0.00310877234317638 987 79 14 0.177215189873418 0.0141843971631206
TF TF:M06260 Factor: ZNF91; motif: GTKAAGCCRM 0.0032376160909149 20 64 3 0.046875 0.15
TF TF:M02089 Factor: E2F-3; motif: GGCGGGN 0.00357329799560959 13173 54 49 0.907407407407407 0.00371972975024672
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.00361209747475275 4592 80 35 0.4375 0.00762195121951219
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.00369776435832824 11275 83 65 0.783132530120482 0.0057649667405765
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.00369776435832824 4607 83 36 0.433734939759036 0.00781419578901671
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.00375836041717659 12401 83 69 0.831325301204819 0.00556406741391823
TF TF:M09613 Factor: Fli-1; motif: RCMGGAAGYGNNN 0.00375836041717659 5169 59 30 0.508474576271186 0.00580383052814858
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 0.00378677726683342 14997 55 53 0.963636363636364 0.00353404014136161
TF TF:M08390 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA 0.00378677726683342 11072 65 52 0.8 0.00469653179190751
TF TF:M09904 Factor: Elk-1; motif: RCCGGAAGTGN 0.0038046697648463 8164 65 43 0.661538461538462 0.00526702596766291
TF TF:M05439 Factor: RREB-1; motif: GGGWCSA 0.00389746244041264 8635 12 12 1 0.00138969310943833
TF TF:M02070_1 Factor: TEL1; motif: CNCGGAANNN; match class: 1 0.00402074405677534 4841 83 37 0.44578313253012 0.0076430489568271
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.00440222928057974 8273 74 48 0.648648648648649 0.00580200652725734
TF TF:M11480_1 Factor: AP-2alpha; motif: NGCCTSAGGCN; match class: 1 0.00448468896680161 5842 8 8 1 0.00136939404313591
TF TF:M09918_1 Factor: Pet-1; motif: GCNGGAAGYG; match class: 1 0.00452843920440345 7159 54 34 0.62962962962963 0.00474926665735438
TF TF:M12273_1 Factor: YY1; motif: GGCSGCCATTTTGN; match class: 1 0.00462675014814386 1261 83 16 0.192771084337349 0.0126883425852498
TF TF:M09900 Factor: Elf-1; motif: NNANCCGGAAGTGS 0.00490918317305854 5219 65 32 0.492307692307692 0.00613144280513508
TF TF:M03969 Factor: ELF5; motif: ANSMGGAAGTN 0.00490918317305854 3339 76 27 0.355263157894737 0.00808625336927224
TF TF:M03982 Factor: ETV4; motif: ACCGGAAGTN 0.00490918317305854 6826 76 43 0.565789473684211 0.00629944330501025
TF TF:M11430 Factor: PEA3; motif: NACCGGAAGTN 0.00490918317305854 10865 83 63 0.759036144578313 0.00579843534284399
TF TF:M03921 Factor: SP3; motif: NCCACGCCCMC 0.00490918317305854 3856 81 31 0.382716049382716 0.00803941908713693
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.00490918317305854 4639 32 18 0.5625 0.00388014658331537
TF TF:M11450 Factor: Elf-1; motif: NANSCGGAAGTR 0.00493907979097133 5601 82 40 0.48780487804878 0.00714158186038207
TF TF:M00803_1 Factor: E2F; motif: GGCGSG; match class: 1 0.00524372056397078 10230 54 42 0.777777777777778 0.00410557184750733
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.00529234492533186 10512 76 57 0.75 0.00542237442922374
TF TF:M11530_1 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN; match class: 1 0.00529234492533186 13449 83 72 0.867469879518072 0.00535355788534464
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 0.00529234492533186 14575 55 52 0.945454545454545 0.00356775300171527
TF TF:M11427_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00529234492533186 4606 82 35 0.426829268292683 0.00759878419452888
TF TF:M08225_1 Factor: Elk-1:Pax-5; motif: ACCGGAACYACGCWTSANYG; match class: 1 0.00534856741785819 7993 73 46 0.63013698630137 0.00575503565619917
TF TF:M09892 Factor: E2F-1; motif: NNNNGGCGGGAARN 0.00534856741785819 13528 55 50 0.909090909090909 0.00369603784742756
TF TF:M11880 Factor: pax-6; motif: NYACGCWTSANYGMNCN 0.00534856741785819 13087 82 70 0.853658536585366 0.00534881943913808
TF TF:M11451 Factor: Elf-1; motif: NANCCGGAAGTN 0.0055428603853466 6886 76 43 0.565789473684211 0.00624455416787685
TF TF:M07380_1 Factor: E2F-4; motif: NTTTCSCGCC; match class: 1 0.00561195460303409 7965 43 30 0.697674418604651 0.00376647834274953
TF TF:M11428 Factor: PEA3; motif: NACCGGAAGTN 0.00561569735207325 7186 65 39 0.6 0.00542721959365433
TF TF:M11480 Factor: AP-2alpha; motif: NGCCTSAGGCN 0.00561569735207325 6186 8 8 1 0.00129324280633689
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.0057242616876653 12747 52 46 0.884615384615385 0.00360869224131168
TF TF:M03970 Factor: ELK1; motif: ACCGGAAGTN 0.00584239710489465 4782 74 33 0.445945945945946 0.006900878293601
TF TF:M02067 Factor: ER71; motif: ACCGGAARYN 0.0059051545440664 5930 74 38 0.513513513513513 0.00640809443507589
TF TF:M04710_1 Factor: CHD2; motif: TCTCGCGAG; match class: 1 0.00604090022516016 11477 53 44 0.830188679245283 0.00383375446545264
TF TF:M09723_1 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS; match class: 1 0.00642706235490509 6113 58 32 0.551724137931034 0.00523474562407983
TF TF:M02073 Factor: Fli-1; motif: ACCGGAAGYN 0.00652713368757489 5839 83 41 0.493975903614458 0.00702175029970885
TF TF:M12165 Factor: BTEB2; motif: NCCACRCCCN 0.00671952793257118 4901 76 34 0.447368421052632 0.00693735972250561
TF TF:M03971 Factor: ELK1; motif: NACTTCCGSCGGAAGYN 0.00671952793257118 11293 83 64 0.771084337349398 0.00566722748605331
TF TF:M11452 Factor: Elf-1; motif: NANGCGGAAGTR 0.00671952793257118 6276 83 43 0.518072289156627 0.0068514977692798
TF TF:M03981 Factor: ETV3; motif: ACCGGAAGTN 0.00671952793257118 2327 65 19 0.292307692307692 0.0081650193382037
TF TF:M12173 Factor: GKLF; motif: NNCCMCRCCCN 0.00688598652022421 10023 43 34 0.790697674418605 0.00339219794472713
TF TF:M04698 Factor: GABP-alpha; motif: CACTTCCGG 0.0069908136142237 3196 65 23 0.353846153846154 0.00719649561952441
TF TF:M11379 Factor: ESE-1; motif: ACCCGGAAGTRNNNNNNNNWWWW 0.00712345645251131 3200 61 22 0.360655737704918 0.006875
TF TF:M08894 Factor: OVOL; motif: ANRTAACGG 0.00717888428617061 8109 77 48 0.623376623376623 0.00591934887162412
TF TF:M09607 Factor: SAP-1; motif: ACCGGAAGTNN 0.00741931052380232 4727 82 35 0.426829268292683 0.00740427332346097
TF TF:M08525 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM 0.00750593531606068 17065 61 61 1 0.00357456782888954
TF TF:M10849 Factor: Cdx-2; motif: NRTCGTAANNNN 0.00767479951512602 11163 53 43 0.811320754716981 0.00385201110812506
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.00770845922719271 6033 74 38 0.513513513513513 0.0062986905353887
TF TF:M11882 Factor: pax-6; motif: NYACGCNYSANYGMNCN 0.00803876814094137 15490 65 62 0.953846153846154 0.0040025823111685
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.00806092769180875 10253 58 44 0.758620689655172 0.00429142689944407
TF TF:M11531_1 Factor: E2F-2; motif: GCGCGCGCGYW; match class: 1 0.00852954829915627 12351 55 47 0.854545454545454 0.00380535988988746
TF TF:M00652 Factor: NRF-1; motif: CGCATGCGCR 0.00852954829915627 1376 83 16 0.192771084337349 0.0116279069767442
TF TF:M04710 Factor: CHD2; motif: TCTCGCGAG 0.00852954829915627 14109 53 49 0.924528301886792 0.00347296052165285
TF TF:M08526 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN 0.00882522984972688 16867 55 55 1 0.00326080512242841
TF TF:M09904_1 Factor: Elk-1; motif: RCCGGAAGTGN; match class: 1 0.00886985232826916 2743 32 13 0.40625 0.004739336492891
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.00886985232826916 5745 83 40 0.481927710843373 0.00696257615317668
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.00901664843879402 3759 83 30 0.36144578313253 0.00798084596967279
TF TF:M01752_1 Factor: ERG; motif: ACCGGAART; match class: 1 0.00924721457545088 3705 73 27 0.36986301369863 0.00728744939271255
TF TF:M08207_1 Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT; match class: 1 0.00924721457545088 15466 55 53 0.963636363636364 0.00342687184792448
TF TF:M11479_1 Factor: AP-2alpha; motif: NGCCTNAGGCN; match class: 1 0.00950873005864804 3649 35 16 0.457142857142857 0.00438476294875308
TF TF:M01035_1 Factor: YY1; motif: NYNKCCATNTT; match class: 1 0.00956541408547527 1112 83 14 0.168674698795181 0.012589928057554
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.00959257710262729 4963 74 33 0.445945945945946 0.00664920411041709
TF TF:M09973 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN 0.00959257710262729 10853 56 44 0.785714285714286 0.00405417856813784
TF TF:M00430_1 Factor: E2F-1; motif: NTTSGCGG; match class: 1 0.00994059978979508 2524 58 18 0.310344827586207 0.00713153724247227
TF TF:M10018_1 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS; match class: 1 0.00994059978979508 851 83 12 0.144578313253012 0.0141010575793184
TF TF:M02090_1 Factor: E2F-4; motif: GCGGGAAANA; match class: 1 0.0101106490789764 6378 53 30 0.566037735849057 0.00470366886171214
TF TF:M10785 Factor: hoxa9; motif: RTCGTWANNN 0.0102322345653156 5632 64 32 0.5 0.00568181818181818
TF TF:M11449 Factor: Elf-1; motif: NANCCGGAAGTN 0.0103383667157761 4305 81 32 0.395061728395062 0.00743321718931475
TF TF:M11883 Factor: pax-6; motif: NYACGCNTSRNYGCNYN 0.0103383667157761 13445 83 71 0.855421686746988 0.0052807735217553
TF TF:M03925_1 Factor: YY2; motif: NCCGCCATNTY; match class: 1 0.0104278478929297 765 9 4 0.444444444444444 0.00522875816993464
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.0110294740608777 11423 60 48 0.8 0.00420204849864309
TF TF:M11877 Factor: pax-2; motif: NCGTCACGCNYSRNYGCNYN 0.0111629931812971 11523 80 62 0.775 0.00538054326130348
TF TF:M03990 Factor: GABPA; motif: ACCGGAAGTN 0.0116075952605202 5258 74 34 0.459459459459459 0.00646633701027006
TF TF:M01240 Factor: BEN; motif: CAGCGRNV 0.0116501383937559 16498 60 59 0.983333333333333 0.00357619105346103
TF TF:M08451 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA 0.0118336678401181 8421 82 51 0.621951219512195 0.00605628785179907
TF TF:M08206 Factor: E2F-3:Prrxl1; motif: SGCGCTAATTNN 0.0120003652767776 11802 30 27 0.9 0.00228774783934926
TF TF:M04147 Factor: TFAP2A; motif: NGCCYSAGGCN 0.0120130005097249 5095 6 6 1 0.00117762512266928
TF TF:M01258 Factor: GABP; motif: CACTTCCGGNNN 0.0120130005097249 2838 76 23 0.302631578947368 0.00810429880197322
TF TF:M03983 Factor: ETV5; motif: NCCGGAWGYN 0.0120148200513766 3129 74 24 0.324324324324324 0.00767018216682646
TF TF:M02061 Factor: ERF; motif: ACCGGAARYN 0.0120148200513766 2579 73 21 0.287671232876712 0.0081426909654905
TF TF:M09901 Factor: nerf; motif: NNNCCGGAAGTGN 0.0120148200513766 5352 76 35 0.460526315789474 0.00653961136023916
TF TF:M11485_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.0120148200513766 6203 7 7 1 0.00112848621634693
TF TF:M12186 Factor: BTEB4; motif: NCCACGCCCM 0.0120148200513766 9135 61 42 0.688524590163934 0.00459770114942529
TF TF:M11987 Factor: NFATc3; motif: NAYGGAAANW 0.0120148200513766 2409 83 22 0.265060240963855 0.0091324200913242
TF TF:M00737_1 Factor: E2F-1:DP-2; motif: TTTSSCGC; match class: 1 0.0120148200513766 2933 11 7 0.636363636363636 0.00238663484486874
TF TF:M00793_1 Factor: YY1; motif: GCCATNTTN; match class: 1 0.0120944205199288 819 9 4 0.444444444444444 0.00488400488400488
TF TF:M00360_1 Factor: Pax-3; motif: TCGTCACRCTTHM; match class: 1 0.012148583549602 5491 69 33 0.478260869565217 0.00600983427426698
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.012148583549602 13270 75 64 0.853333333333333 0.00482290881688018
TF TF:M02063_1 Factor: c-ets-1; motif: ACCGGAWGTN; match class: 1 0.0121988014703387 2396 73 20 0.273972602739726 0.00834724540901502
TF TF:M00981 Factor: CREB,; motif: NTGACGTNA 0.0122002983323478 8345 81 50 0.617283950617284 0.00599161174355902
TF TF:M02036 Factor: WT1; motif: CGCCCCCNCN 0.0122002983323478 9767 58 42 0.724137931034483 0.00430019453260981
TF TF:M09913 Factor: ER81; motif: NNCCGGAAGYG 0.0129364999259435 2871 76 23 0.302631578947368 0.00801114594218042
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.0129364999259435 11053 53 42 0.792452830188679 0.00379987333755541
TF TF:M08208_1 Factor: E2F-3:FOXI1; motif: NGACACCGCGCCCAC; match class: 1 0.0129364999259435 7127 33 22 0.666666666666667 0.0030868528132454
TF TF:M11077 Factor: TCFL5; motif: KCACGCGCMC 0.0130011976670017 990 65 11 0.169230769230769 0.0111111111111111
TF TF:M01165 Factor: Elk-1; motif: RACCGGAAGTR 0.0133751262180743 7773 76 45 0.592105263157895 0.00578927055191046
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 0.0135158959302013 6334 43 25 0.581395348837209 0.00394695295232081
TF TF:M12188 Factor: KLF17; motif: NGMCMCRCCCTN 0.0135158959302013 3673 80 28 0.35 0.00762319629730466
TF TF:M08415 Factor: TEF-3:Elf-1; motif: RGAATGCGGAAGTN 0.0135158959302013 9334 76 51 0.671052631578947 0.00546389543604028
TF TF:M09603 Factor: Egr-1; motif: NNNNNGYGKGGGNGGGNN 0.0135158959302013 4627 53 24 0.452830188679245 0.00518694618543333
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.0135158959302013 10585 83 60 0.72289156626506 0.00566839867737364
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0138252244884198 4902 83 35 0.421686746987952 0.00713994288045696
TF TF:M08423 Factor: TEF-3:ER81; motif: ACCGGAAATRCC 0.0138812847207745 3845 77 28 0.363636363636364 0.00728218465539662
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.0139023746958288 4677 74 31 0.418918918918919 0.00662818045755826
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.0141658101177557 14429 59 54 0.915254237288136 0.00374246309515559
TF TF:M12148 Factor: SP8; motif: NCCACGCCCMCN 0.0141658101177557 2907 76 23 0.302631578947368 0.00791193670450636
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.0141658101177557 10939 81 60 0.740740740740741 0.00548496206234574
TF TF:M11603 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0141658101177557 16361 55 54 0.981818181818182 0.00330053175233788
TF TF:M10086 Factor: TAFII250; motif: RARRWGGCGGMGGNGR 0.0141982495347843 9262 82 54 0.658536585365854 0.00583027423882531
TF TF:M12184 Factor: KLF14; motif: NRCCACGCCCMCN 0.0143167450761382 2532 76 21 0.276315789473684 0.00829383886255924
TF TF:M08760 Factor: ETV7; motif: NNSCGGAAGTR 0.0143167450761382 2349 65 18 0.276923076923077 0.00766283524904215
TF TF:M12150 Factor: SP9; motif: NCCACGCCCMCN 0.0147510609728249 2353 76 20 0.263157894736842 0.00849978750531237
TF TF:M11420 Factor: ER81; motif: NACCGGAAGTN 0.0147510609728249 3210 74 24 0.324324324324324 0.00747663551401869
TF TF:M01894_1 Factor: YY1; motif: CCATNTT; match class: 1 0.0147650321856575 1711 9 5 0.555555555555556 0.00292226767971946
TF TF:M02107 Factor: NF-YC; motif: NRGCCAATYAGMGC 0.0152060178549448 1001 21 6 0.285714285714286 0.00599400599400599
TF TF:M03971_1 Factor: ELK1; motif: NACTTCCGSCGGAAGYN; match class: 1 0.0155197304858963 7157 20 15 0.75 0.00209585021657119
TF TF:M08344 Factor: HOXB2:ER81; motif: ACCGGAAATGA 0.0161661970060051 101 72 4 0.0555555555555556 0.0396039603960396
TF TF:M08457 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY 0.0161661970060051 12052 60 49 0.816666666666667 0.00406571523398606
TF TF:M02068 Factor: etv3; motif: ACCGGAAGYN 0.0162195232969193 3443 74 25 0.337837837837838 0.00726110949753122
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.0162775882011039 14593 54 50 0.925925925925926 0.00342630028095662
TF TF:M03925 Factor: YY2; motif: NCCGCCATNTY 0.0166628727382049 4641 63 27 0.428571428571429 0.00581771170006464
TF TF:M09893_1 Factor: E2F-3; motif: NNGGCGGGAAA; match class: 1 0.0166628727382049 1322 44 10 0.227272727272727 0.0075642965204236
TF TF:M03895 Factor: CTCF; motif: WGCGCCMYCTAGYGGYN 0.0172279270916958 9251 46 33 0.717391304347826 0.00356718192627824
TF TF:M08345 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN 0.0172421583790558 8027 79 47 0.594936708860759 0.00585523856982683
TF TF:M03865 Factor: Blimp-1; motif: NRGRAAGKGAAAGK 0.0175407921809192 1048 4 3 0.75 0.00286259541984733
TF TF:M03876 Factor: Kaiso; motif: GCMGGGRGCRGS 0.0176194072306591 13622 54 48 0.888888888888889 0.00352371164293055
TF TF:M11394 Factor: Erg; motif: NACMGGAARTN 0.0177305487158204 4051 75 28 0.373333333333333 0.00691187361145396
TF TF:M09605 Factor: Elf-1; motif: NAANCMGGAAGTGN 0.0177305487158204 5778 81 38 0.469135802469136 0.006576670128072
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.0177305487158204 11232 83 62 0.746987951807229 0.00551994301994302
TF TF:M08020 Factor: YY2; motif: NNCCGCCATTW 0.0181495916606985 1331 7 4 0.571428571428571 0.00300525920360631
TF TF:M11488_1 Factor: CP2; motif: WACCGGTTNNAACCGGWT; match class: 1 0.0182136309656941 635 6 3 0.5 0.0047244094488189
TF TF:M08222_1 Factor: Elk-1:HOXB13; motif: ACCGGAAGTNGTAAAN; match class: 1 0.0185533153290375 2063 25 9 0.36 0.00436257876878332
TF TF:M08523 Factor: E2F-1:TBR2; motif: NGGTGNNANGGCGCNNTNNCRNNN 0.0188862878527 12160 53 44 0.830188679245283 0.00361842105263158
TF TF:M11818_1 Factor: T3R-beta; motif: NTGACCTYRNYRAGGTCAN; match class: 1 0.0189112602679164 11261 22 20 0.909090909090909 0.00177604120415594
TF TF:M11993 Factor: NFATc4; motif: NAYGGAAANW 0.0192177568084978 944 73 11 0.150684931506849 0.0116525423728814
TF TF:M06623 Factor: ZNF778; motif: NTMAGWTTGCGC 0.0199938442260745 119 29 3 0.103448275862069 0.0252100840336134
TF TF:M07415 Factor: Elf-1; motif: AWCCCGGAAGTN 0.0204102450599781 7978 76 45 0.592105263157895 0.00564051140636751
TF TF:M09935_1 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN; match class: 1 0.0204102450599781 1047 38 8 0.210526315789474 0.00764087870105062
TF TF:M06292 Factor: ZNF766; motif: NCGTGAAGGAAA 0.0204102450599781 146 24 3 0.125 0.0205479452054795
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 0.020574636109815 1657 10 5 0.5 0.00301750150875075
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.0209205054387467 13227 18 18 1 0.00136085280108868
TF TF:M11384 Factor: ESE-1; motif: ACCCGGAAGTRNNNNNNNWWWWW 0.0209205054387467 3272 75 24 0.32 0.00733496332518337
TF TF:M09642_1 Factor: p53; motif: RGRCATGTCTGGRCATGYCN; match class: 1 0.0215693475517723 246 15 3 0.2 0.0121951219512195
TF TF:M08220_1 Factor: Elk-1:HOXA3; motif: ACCGGWAATKRNNTNWCNNATTAN; match class: 1 0.0215693475517723 5350 82 36 0.439024390243902 0.00672897196261682
TF TF:M02116 Factor: Sox-10; motif: NACAAWG 0.0225367792591983 14212 36 34 0.944444444444444 0.00239234449760766
TF TF:M11424 Factor: Erm; motif: NNSCGGAWGYN 0.0226708613863733 8149 83 49 0.590361445783133 0.00601300773100994
TF TF:M01035 Factor: YY1; motif: NYNKCCATNTT 0.0226708613863733 5924 83 39 0.469879518072289 0.00658338960162053
TF TF:M09895_1 Factor: E2F-6; motif: NGGGCGGGARRNN; match class: 1 0.0232274237138372 2711 10 6 0.6 0.00221320545924013
TF TF:M11179_1 Factor: ASH-2; motif: ACACGACGCN; match class: 1 0.0234591458674364 165 51 4 0.0784313725490196 0.0242424242424242
TF TF:M11479 Factor: AP-2alpha; motif: NGCCTNAGGCN 0.0235209316213357 4568 35 17 0.485714285714286 0.0037215411558669
TF TF:M09970 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN 0.0236552520856558 7728 56 34 0.607142857142857 0.00439958592132505
TF TF:M10104_1 Factor: YY1; motif: CAARATGGCGGC; match class: 1 0.0236552520856558 1138 83 13 0.156626506024096 0.0114235500878735
TF TF:M04696_1 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN; match class: 1 0.0236552520856558 1973 9 5 0.555555555555556 0.00253421186011151
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.0236552520856558 14096 52 47 0.903846153846154 0.00333427922814983
TF TF:M11402 Factor: Fli-1; motif: NACCGGAARTN 0.0238638612212233 3885 76 27 0.355263157894737 0.00694980694980695
TF TF:M07354 Factor: Egr-1; motif: GCGGGGGCGG 0.0250598276486836 7801 72 42 0.583333333333333 0.00538392513780285
TF TF:M11486_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.0250827262117301 2952 43 15 0.348837209302326 0.00508130081300813
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.0252559025764956 5133 32 17 0.53125 0.00331190337034872
TF TF:M10086_1 Factor: TAFII250; motif: RARRWGGCGGMGGNGR; match class: 1 0.0254959410800702 4153 79 29 0.367088607594937 0.00698290392487359
TF TF:M00325 Factor: NRSE; motif: TTYAGCWCCDCGGASAGYRCC 0.0254959410800702 1578 11 5 0.454545454545455 0.00316856780735108
TF TF:M11415 Factor: GABP-alpha; motif: NRCCGGAAGTN 0.0254959410800702 3257 81 25 0.308641975308642 0.00767577525330058
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.0260270699470036 4201 61 24 0.39344262295082 0.00571292549393002
TF TF:M08313 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR 0.0262693391578087 15419 83 76 0.91566265060241 0.00492898372138271
TF TF:M07084 Factor: E2F-4; motif: NGGCGGGAARN 0.0267212183231256 10834 60 45 0.75 0.00415359054827395
TF TF:M11018 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN 0.0267531384415682 16955 61 60 0.983606557377049 0.00353877912120318
TF TF:M08401_1 Factor: POU2F1:ER81; motif: ACCGGATATGCAN; match class: 1 0.0272647232354541 1700 58 13 0.224137931034483 0.00764705882352941
TF TF:M11670 Factor: IRF-5; motif: NYGAAACCGAAACY 0.0272647232354541 871 48 8 0.166666666666667 0.00918484500574053
TF TF:M11337 Factor: ATF-4; motif: GGATGACGTCATCC 0.0272850118881482 2911 62 19 0.306451612903226 0.00652696667811749
TF TF:M10063 Factor: SNF2H; motif: GAATNGAATGGAAWC 0.0272850118881482 734 70 9 0.128571428571429 0.0122615803814714
TF TF:M12158 Factor: KLF15; motif: NCCMCGCCCMCN 0.0272850118881482 11088 56 43 0.767857142857143 0.00387806637806638
TF TF:M11477_1 Factor: AP-2beta; motif: NSCCYNRGGSN; match class: 1 0.0273421270309477 6950 42 25 0.595238095238095 0.00359712230215827
TF TF:M12273 Factor: YY1; motif: GGCSGCCATTTTGN 0.0275679363369662 6229 83 40 0.481927710843373 0.00642157649703002
TF TF:M08220 Factor: Elk-1:HOXA3; motif: ACCGGWAATKRNNTNWCNNATTAN 0.0275679363369662 12140 65 52 0.8 0.0042833607907743
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.0277035740543905 6892 76 40 0.526315789473684 0.00580383052814858
TF TF:M07370 Factor: YY1; motif: NNNNAARATGGNNNN 0.0283371989421376 5811 83 38 0.457831325301205 0.00653932197556359
TF TF:M00032_1 Factor: c-Ets-1(p54); motif: NCMGGAWGYN; match class: 1 0.0283371989421376 2161 36 11 0.305555555555556 0.00509023600185099
TF TF:M11179 Factor: ASH-2; motif: ACACGACGCN 0.0283550542430166 2162 64 16 0.25 0.00740055504162812
TF TF:M12166 Factor: CPBP; motif: NGCCACGCCCN 0.0288622808705546 1328 74 13 0.175675675675676 0.00978915662650602
TF TF:M07234_1 Factor: YY1; motif: CAARATGGCNGC; match class: 1 0.0288622808705546 1177 83 13 0.156626506024096 0.0110450297366185
TF TF:M00024 Factor: E2F-1; motif: TWSGCGCGAAAAYKR 0.0288622808705546 8919 76 48 0.631578947368421 0.00538176925664312
TF TF:M11436 Factor: SAP-1; motif: NRNCGGAWRYN 0.0289061317673865 1431 69 13 0.188405797101449 0.00908455625436757
TF TF:M04810 Factor: USF2; motif: AAGTCACG 0.0292701743587959 5496 79 35 0.443037974683544 0.00636826783114993
TF TF:M12151 Factor: Sp1; motif: NWRGCCMCGCCCMCN 0.0292701743587959 6821 54 30 0.555555555555556 0.00439818208473831
TF TF:M07039 Factor: ETF; motif: CCCCGCCCCYN 0.0292701743587959 16384 60 58 0.966666666666667 0.0035400390625
TF TF:M00177 Factor: CREB; motif: NSTGACGTAANN 0.0292860391160097 5221 27 15 0.555555555555556 0.00287301283279065
TF TF:M11018_1 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN; match class: 1 0.0292860391160097 15920 61 58 0.950819672131147 0.00364321608040201
TF TF:M04826 Factor: p300; motif: ACNTCCG 0.0294159997267943 17806 65 65 1 0.00365045490284174
TF TF:M11451_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.0308651722494918 2112 32 10 0.3125 0.00473484848484848
TF TF:M04694_1 Factor: NRF-1; motif: CNCTGCGCATGCGC; match class: 1 0.0308651722494918 466 52 6 0.115384615384615 0.0128755364806867
TF TF:M08757 Factor: nerf; motif: AAMCCGGAAGTN 0.0309301818485625 715 74 9 0.121621621621622 0.0125874125874126
TF TF:M00736_1 Factor: E2F-1:DP-1; motif: TTTCSCGC; match class: 1 0.0309301818485625 4639 60 25 0.416666666666667 0.0053890924768269
TF TF:M09898 Factor: Egr-2; motif: GNGRRNGWGKGGGNGGRG 0.0309301818485625 6484 71 36 0.507042253521127 0.00555212831585441
TF TF:M11419 Factor: ER81; motif: NNCCGGAWGYN 0.0317842107223209 5699 40 21 0.525 0.00368485699245482
TF TF:M11725_1 Factor: B-Myb; motif: NTAACSGTYRN; match class: 1 0.0319887481367948 169 57 4 0.0701754385964912 0.0236686390532544
TF TF:M08209_1 Factor: E2F-3:FOXO6; motif: NAATGACACGCGCCCMC; match class: 1 0.0321080487245132 7798 69 40 0.579710144927536 0.00512952038984355
TF TF:M11457 Factor: nerf; motif: NANGCGGAAGTR 0.0321080487245132 1082 81 12 0.148148148148148 0.011090573012939
TF TF:M07222 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR 0.0321080487245132 714 7 3 0.428571428571429 0.00420168067226891
TF TF:M07100_1 Factor: HSF1; motif: NTTCTRGAANNTTCY; match class: 1 0.0321080487245132 514 48 6 0.125 0.0116731517509728
TF TF:M01118_1 Factor: WT1; motif: SMCNCCNSC; match class: 1 0.0321080487245132 2766 52 16 0.307692307692308 0.00578452639190166
TF TF:M00032 Factor: c-Ets-1(p54); motif: NCMGGAWGYN 0.0321080487245132 7858 81 46 0.567901234567901 0.00585390684652583
TF TF:M03791 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY 0.0322788191831315 2969 81 23 0.283950617283951 0.00774671606601549
TF TF:M11818 Factor: T3R-beta; motif: NTGACCTYRNYRAGGTCAN 0.0324613082874142 11824 22 20 0.909090909090909 0.0016914749661705
TF TF:M09723 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS 0.0324613082874142 10156 54 39 0.722222222222222 0.0038400945254037
TF TF:M11335 Factor: ATF-4; motif: GGATGACGTCATCC 0.0324613082874142 2292 62 16 0.258064516129032 0.00698080279232112
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.0327589658928037 4024 76 27 0.355263157894737 0.00670974155069582
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.0327589658928037 14106 55 49 0.890909090909091 0.00347369913511981
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.0327589658928037 7544 44 27 0.613636363636364 0.00357900318133616
TF TF:M12180 Factor: BTEB3; motif: NRCCACGCCCMCN 0.0327589658928037 2088 74 17 0.22972972972973 0.00814176245210728
TF TF:M04517 Factor: E2F2; motif: AAAATGGCGCCATTTT 0.0334969921660742 9190 26 20 0.769230769230769 0.00217627856365615
TF TF:M02062_1 Factor: Erg; motif: ACCGGAAGTN; match class: 1 0.0335674763010848 2718 73 20 0.273972602739726 0.00735835172921266
TF TF:M01203 Factor: SPI1; motif: NNAAWGNGGAASTNNNN 0.033911642115364 2643 75 20 0.266666666666667 0.00756715853197124
TF TF:M09905_1 Factor: SAP-1; motif: NNCCGGAAGTGN; match class: 1 0.034082782783842 2989 32 12 0.375 0.0040147206423553
TF TF:M05439_1 Factor: RREB-1; motif: GGGWCSA; match class: 1 0.034082782783842 3200 34 13 0.382352941176471 0.0040625
TF TF:M01214 Factor: ESE-1; motif: NSMGGAARTN 0.0341497907059046 7559 82 45 0.548780487804878 0.00595316840851965
TF TF:M02055 Factor: ESE-1; motif: NSMGGAARTN 0.0341497907059046 7559 82 45 0.548780487804878 0.00595316840851965
TF TF:M10438 Factor: ZF5; motif: GGSGCGCGS 0.0342980939318019 16228 83 78 0.939759036144578 0.0048065072713828
TF TF:M11490_1 Factor: LBP-1; motif: NRCCGGTNNNNACCGGYN; match class: 1 0.0349927438928312 5988 16 11 0.6875 0.00183700734802939
TF TF:M07370_1 Factor: YY1; motif: NNNNAARATGGNNNN; match class: 1 0.0352269660235698 1076 83 12 0.144578313253012 0.0111524163568773
TF TF:M00982 Factor: KROX; motif: CCCGCCCCCRCCCC 0.0352269660235698 7815 55 33 0.6 0.00422264875239923
TF TF:M02053_1 Factor: ELF1; motif: NCCGGAARTN; match class: 1 0.0353232774622867 1559 74 14 0.189189189189189 0.00898011545862733
TF TF:M07261 Factor: LKLF; motif: GGGGTGGKSN 0.035607913302321 9774 73 49 0.671232876712329 0.00501330059341109
TF TF:M01073 Factor: HIC1; motif: NNNGGKTGCCCSNNNNNN 0.0362392386105278 4088 4 4 1 0.000978473581213307
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.0362392386105278 10233 54 39 0.722222222222222 0.00381119906185869
TF TF:M00113 Factor: CREB; motif: NNGNTGACGTNN 0.0362392386105278 4801 78 31 0.397435897435897 0.00645698812747344
TF TF:M08213 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN 0.0370101074304624 6273 8 7 0.875 0.0011158935118763
TF TF:M11005_1 Factor: LHX4; motif: NNCRTTAN; match class: 1 0.0370101074304624 4203 81 29 0.358024691358025 0.00689983345229598
TF TF:M12275 Factor: YY1; motif: NGCCGCCATYTTGN 0.0370101074304624 7043 83 43 0.518072289156627 0.00610535283259974
TF TF:M11337_1 Factor: ATF-4; motif: GGATGACGTCATCC; match class: 1 0.0372853517655282 2806 62 18 0.290322580645161 0.00641482537419815
TF TF:M08993 Factor: ZNF777; motif: GTCCGYCCCGTCSAACAAT 0.0376911343715017 10617 70 50 0.714285714285714 0.00470942827540737
TF TF:M11433_1 Factor: Elk-1; motif: NRCCGGAAGTN; match class: 1 0.0380593238598989 2261 76 18 0.236842105263158 0.00796107916850951
TF TF:M07611 Factor: p54NRB; motif: GRNNNMGGATGRMNNCGGA 0.0380593238598989 6991 6 6 1 0.000858246316692891
TF TF:M00243 Factor: Egr-1; motif: WTGCGTGGGCGK 0.0380593238598989 5356 54 25 0.462962962962963 0.00466766243465273
TF TF:M01078_1 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN; match class: 1 0.0382665796220715 2448 44 13 0.295454545454545 0.00531045751633987
TF TF:M00803 Factor: E2F; motif: GGCGSG 0.0384825165747437 13190 54 46 0.851851851851852 0.00348749052312358
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.0389389276767279 10281 54 39 0.722222222222222 0.00379340531076743
TF TF:M11487 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.0390083031183043 4329 8 6 0.75 0.00138600138600139
TF TF:M11432_1 Factor: Elk-1; motif: NACMGGAAGTN; match class: 1 0.0393444360126961 1525 13 5 0.384615384615385 0.00327868852459016
TF TF:M00341 Factor: GABP; motif: VCCGGAAGNGCR 0.0393444360126961 8224 57 35 0.614035087719298 0.00425583657587549
TF TF:M11421 Factor: ER81; motif: NACCGGAAGTN 0.0399667835261711 2341 74 18 0.243243243243243 0.00768902178556173
TF TF:M11795 Factor: NR1B1; motif: NRGGTCANNRGGTCAN 0.0400801598635261 7962 22 16 0.727272727272727 0.00200954534036674
TF TF:M09611 Factor: ER81; motif: NNNGRCMGGAAGYRNNNNNNNS 0.0405155059702278 2666 76 20 0.263157894736842 0.00750187546886722
TF TF:M11876 Factor: pax-2; motif: NSGTCACGCWTSANYGMNYN 0.0410118444464547 6198 78 37 0.474358974358974 0.00596966763472088
TF TF:M04714_1 Factor: Elf-1; motif: ACTTCCGGG; match class: 1 0.0410118444464547 2659 32 11 0.34375 0.00413689356901091
TF TF:M11382_1 Factor: ESE-1; motif: NWTRCGGAWGCN; match class: 1 0.0411607996973114 4112 25 12 0.48 0.00291828793774319
TF TF:M00932_1 Factor: Sp1; motif: NNGGGGCGGGGNN; match class: 1 0.0414961295686671 6047 54 27 0.5 0.00446502397883248
TF TF:M12164 Factor: BTEB2; motif: NMCACGCCCN 0.0414961295686671 2984 64 19 0.296875 0.00636729222520107
TF TF:M03827 Factor: HNF-3alpha; motif: RYAAACAN 0.0414961295686671 1226 16 5 0.3125 0.00407830342577488
TF TF:M01047 Factor: AP-2alphaA; motif: ANMGCCTNAGGCKNT 0.0420335974525538 9237 8 8 1 0.000866082061275306
TF TF:M01047_1 Factor: AP-2alphaA; motif: ANMGCCTNAGGCKNT; match class: 1 0.0420335974525538 9237 8 8 1 0.000866082061275306
TF TF:M00976 Factor: AhR,; motif: NRCGTGNGN 0.0428986941426813 4351 4 4 1 0.000919328889910365
TF TF:M04064_1 Factor: Pax-5; motif: NGTCACGCWTSANTGMNY; match class: 1 0.0432612053939996 3538 55 19 0.345454545454545 0.00537026568682872
TF TF:M03982_1 Factor: ETV4; motif: ACCGGAAGTN; match class: 1 0.0432612053939996 2009 73 16 0.219178082191781 0.0079641612742658
TF TF:M10112_1 Factor: Miz-1; motif: NNRGGWGGGGGAGGGGMRR; match class: 1 0.0434991687399285 4075 59 22 0.372881355932203 0.00539877300613497
TF TF:M11725 Factor: B-Myb; motif: NTAACSGTYRN 0.0436483709925213 863 43 7 0.162790697674419 0.00811123986095017
TF TF:M11455 Factor: ELFR; motif: NANSCGGAAGTN 0.0441434128961447 631 74 8 0.108108108108108 0.0126782884310618
TF TF:M11671 Factor: IRF-5; motif: NCGAAACCGAAACY 0.0442165891913182 389 48 5 0.104166666666667 0.012853470437018
TF TF:M10098_1 Factor: DP-1; motif: NRNNGGCGGGAANN; match class: 1 0.0444238612961235 2168 10 5 0.5 0.00230627306273063
TF TF:M09930 Factor: foxm1; motif: TGTTTRCTYWNN 0.044438318177732 6816 25 16 0.64 0.00234741784037559
TF TF:M07089 Factor: Fli-1; motif: RCAGGAAGTGR 0.044438318177732 4928 59 25 0.423728813559322 0.00507305194805195
TF TF:M00793 Factor: YY1; motif: GCCATNTTN 0.044438318177732 5186 83 34 0.409638554216867 0.00655611261087543
TF TF:M12149 Factor: SP9; motif: RCCACGCCCMCY 0.044438318177732 2379 74 18 0.243243243243243 0.00756620428751576
TF TF:M08266_1 Factor: ER71:Pax-5; motif: ACCGGAACYACGCWTSANTG; match class: 1 0.044438318177732 8979 48 32 0.666666666666667 0.00356387125515091
TF TF:M09896 Factor: E2F-7; motif: GRGGCGGGAANNN 0.044438318177732 9927 33 25 0.757575757575758 0.00251838420469427
TF TF:M03920 Factor: SP1; motif: RCCMCRCCCMC 0.0445227896753199 7283 55 31 0.563636363636364 0.00425648771110806
TF TF:M11877_1 Factor: pax-2; motif: NCGTCACGCNYSRNYGCNYN; match class: 1 0.0445227896753199 5304 61 27 0.442622950819672 0.00509049773755656
TF TF:M08523_1 Factor: E2F-1:TBR2; motif: NGGTGNNANGGCGCNNTNNCRNNN; match class: 1 0.0445570137136093 7423 52 30 0.576923076923077 0.004041492657955
TF TF:M07234 Factor: YY1; motif: CAARATGGCNGC 0.0447506512651841 6045 83 38 0.457831325301205 0.00628618693134822
TF TF:M12154 Factor: Sp3; motif: NGCCACGCCCMCN 0.0450696090935085 2190 74 17 0.22972972972973 0.00776255707762557
TF TF:M10849_1 Factor: Cdx-2; motif: NRTCGTAANNNN; match class: 1 0.0450696090935085 4497 81 30 0.37037037037037 0.0066711140760507
TF TF:M03924 Factor: YY1; motif: NNCGCCATTNN 0.0452088211573537 10084 72 49 0.680555555555556 0.00485918286394288
TF TF:M12147 Factor: SP8; motif: RNCACGCCCMCN 0.0452509227440377 2465 45 13 0.288888888888889 0.00527383367139959
TF TF:M11218 Factor: CREB1; motif: NRTGAYGCGTN 0.0452509227440377 8461 62 38 0.612903225806452 0.00449119489422054
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.0460218901695177 10430 75 52 0.693333333333333 0.0049856184084372
TF TF:M09972 Factor: BTEB2; motif: WGGGTGKGGCNGGN 0.0460218901695177 9217 56 37 0.660714285714286 0.00401432136269936
TF TF:M09789 Factor: TFDP1; motif: NSGCGGGAANN 0.0464777578978635 2026 20 7 0.35 0.00345508390918065
TF TF:M11078 Factor: TCFL5; motif: KCACGCGCNC 0.0465636037056767 1471 65 12 0.184615384615385 0.00815771583956492
TF TF:M11481_1 Factor: AP-2gamma; motif: NSCCYNRGGSN; match class: 1 0.0465636037056767 4662 56 23 0.410714285714286 0.00493350493350493
TF TF:M11601 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0465636037056767 14823 61 55 0.901639344262295 0.00371044997638805
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.0465636037056767 10419 54 39 0.722222222222222 0.00374316153181687
TF TF:M01588 Factor: GKLF; motif: GCCMCRCCCNNN 0.0465636037056767 8944 52 34 0.653846153846154 0.00380143112701252
TF TF:M03558 Factor: P73; motif: GNNNRRRCNTGCMNNTSASN 0.0465636037056767 4679 59 24 0.406779661016949 0.00512930113272067
TF TF:M08806 Factor: Egr-2; motif: NGTGGGNGGG 0.0465636037056767 1080 55 9 0.163636363636364 0.00833333333333333
TF TF:M08887 Factor: IRF; motif: NNGAAANTGAAANN 0.046578006458247 1267 75 12 0.16 0.00947119179163378
TF TF:M11486 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.046578006458247 3658 39 15 0.384615384615385 0.00410060142154183
TF TF:M02090 Factor: E2F-4; motif: GCGGGAAANA 0.0468176778991667 11966 60 47 0.783333333333333 0.00392779542035768
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.0469286790061537 4056 82 28 0.341463414634146 0.00690335305719921
TF TF:M12153 Factor: Sp3; motif: NGCCACGCCCMCN 0.0469776205912948 6205 56 28 0.5 0.00451248992747784
TF TF:M01592 Factor: LBP9; motif: CCRGNNNNARCCRGYYN 0.0470236035001306 1422 35 8 0.228571428571429 0.00562587904360056
TF TF:M07308 Factor: Sox-2; motif: NNNANAACAAWGRNN 0.0470236035001306 2054 25 8 0.32 0.00389483933787731
TF TF:M04106_1 Factor: RUNX2; motif: NRACCGCAAACCGCAN; match class: 1 0.0471282278994637 8372 55 34 0.618181818181818 0.00406115623506928
TF TF:M02056_1 Factor: ELF4; motif: NCCGGAARTN; match class: 1 0.0474244866817125 1291 74 12 0.162162162162162 0.00929512006196747
TF TF:M09605_1 Factor: Elf-1; motif: NAANCMGGAAGTGN; match class: 1 0.047543652423222 1306 38 8 0.210526315789474 0.00612557427258806
TF TF:M00933_1 Factor: Sp1; motif: CCCCGCCCCN; match class: 1 0.0486258360571058 5166 14 9 0.642857142857143 0.00174216027874564
TF TF:M01208 Factor: FLI-1; motif: CMGGAWGTSAN 0.0493364921070061 6232 56 28 0.5 0.00449293966623877
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.0493368065318086 12729 56 46 0.821428571428571 0.00361379527064184
TF TF:M10851 Factor: Cdx-2; motif: NRTYRTAAAN 0.0495946994482971 2334 65 16 0.246153846153846 0.00685518423307626
TF TF:M09896_1 Factor: E2F-7; motif: GRGGCGGGAANNN; match class: 1 0.0496190531484807 4525 21 11 0.523809523809524 0.00243093922651934

pEpiTp20 transcription factor target enrichment of top program genes

TF enrichment of pEpiTp20
Possible regulators of activation of pEpiTp20 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.