CORUM
|
CORUM:178
|
Respiratory chain complex I (holoenzyme), mitochondrial
|
8.8964168320516e-05
|
44
|
93
|
9
|
0.0967741935483871
|
0.204545454545455
|
CORUM
|
CORUM:2914
|
Respiratory chain complex I (beta subunit) mitochondrial
|
0.00140801234522495
|
16
|
93
|
5
|
0.0537634408602151
|
0.3125
|
GO:BP
|
GO:0022900
|
electron transport chain
|
2.57908179407903e-12
|
180
|
93
|
16
|
0.172043010752688
|
0.0888888888888889
|
GO:BP
|
GO:0006120
|
mitochondrial electron transport, NADH to ubiquinone
|
3.13200016476847e-12
|
56
|
93
|
11
|
0.118279569892473
|
0.196428571428571
|
GO:BP
|
GO:0042773
|
ATP synthesis coupled electron transport
|
3.13200016476847e-12
|
100
|
93
|
13
|
0.139784946236559
|
0.13
|
GO:BP
|
GO:0042775
|
mitochondrial ATP synthesis coupled electron transport
|
3.13200016476847e-12
|
99
|
93
|
13
|
0.139784946236559
|
0.131313131313131
|
GO:BP
|
GO:0022904
|
respiratory electron transport chain
|
1.65858071863079e-11
|
117
|
93
|
13
|
0.139784946236559
|
0.111111111111111
|
GO:BP
|
GO:0006119
|
oxidative phosphorylation
|
1.70670378597217e-11
|
151
|
93
|
14
|
0.150537634408602
|
0.0927152317880795
|
GO:BP
|
GO:0045333
|
cellular respiration
|
7.17231061399271e-09
|
192
|
93
|
13
|
0.139784946236559
|
0.0677083333333333
|
GO:BP
|
GO:0010257
|
NADH dehydrogenase complex assembly
|
1.77847577137459e-08
|
67
|
93
|
9
|
0.0967741935483871
|
0.134328358208955
|
GO:BP
|
GO:0032981
|
mitochondrial respiratory chain complex I assembly
|
1.77847577137459e-08
|
67
|
93
|
9
|
0.0967741935483871
|
0.134328358208955
|
GO:BP
|
GO:0046034
|
ATP metabolic process
|
1.81852876250017e-08
|
314
|
93
|
15
|
0.161290322580645
|
0.0477707006369427
|
GO:BP
|
GO:0006091
|
generation of precursor metabolites and energy
|
4.70932810959878e-07
|
538
|
93
|
17
|
0.182795698924731
|
0.0315985130111524
|
GO:BP
|
GO:0015980
|
energy derivation by oxidation of organic compounds
|
6.2160368440914e-07
|
289
|
93
|
13
|
0.139784946236559
|
0.0449826989619377
|
GO:BP
|
GO:0033108
|
mitochondrial respiratory chain complex assembly
|
6.2160368440914e-07
|
103
|
93
|
9
|
0.0967741935483871
|
0.087378640776699
|
GO:BP
|
GO:0055114
|
obsolete oxidation-reduction process
|
7.22483278905077e-06
|
745
|
103
|
19
|
0.184466019417476
|
0.025503355704698
|
GO:BP
|
GO:0050871
|
positive regulation of B cell activation
|
1.31337370660429e-05
|
151
|
6
|
4
|
0.666666666666667
|
0.0264900662251656
|
GO:BP
|
GO:0050864
|
regulation of B cell activation
|
3.37190662913005e-05
|
194
|
6
|
4
|
0.666666666666667
|
0.0206185567010309
|
GO:BP
|
GO:0007005
|
mitochondrion organization
|
0.000167471539736411
|
561
|
93
|
14
|
0.150537634408602
|
0.0249554367201426
|
GO:BP
|
GO:0030449
|
regulation of complement activation
|
0.000179804773075944
|
110
|
31
|
5
|
0.161290322580645
|
0.0454545454545455
|
GO:BP
|
GO:0042113
|
B cell activation
|
0.000237905578987279
|
330
|
6
|
4
|
0.666666666666667
|
0.0121212121212121
|
GO:BP
|
GO:0051251
|
positive regulation of lymphocyte activation
|
0.00033778760115098
|
365
|
6
|
4
|
0.666666666666667
|
0.010958904109589
|
GO:BP
|
GO:0002920
|
regulation of humoral immune response
|
0.000370723826911661
|
133
|
31
|
5
|
0.161290322580645
|
0.037593984962406
|
GO:BP
|
GO:0006910
|
phagocytosis, recognition
|
0.000370723826911661
|
98
|
6
|
3
|
0.5
|
0.0306122448979592
|
GO:BP
|
GO:0002433
|
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
|
0.000370723826911661
|
135
|
31
|
5
|
0.161290322580645
|
0.037037037037037
|
GO:BP
|
GO:0038096
|
Fc-gamma receptor signaling pathway involved in phagocytosis
|
0.000370723826911661
|
135
|
31
|
5
|
0.161290322580645
|
0.037037037037037
|
GO:BP
|
GO:0038094
|
Fc-gamma receptor signaling pathway
|
0.000382555660236357
|
137
|
31
|
5
|
0.161290322580645
|
0.0364963503649635
|
GO:BP
|
GO:0002431
|
Fc receptor mediated stimulatory signaling pathway
|
0.000407242250082653
|
141
|
31
|
5
|
0.161290322580645
|
0.0354609929078014
|
GO:BP
|
GO:0006958
|
complement activation, classical pathway
|
0.000407242250082653
|
142
|
31
|
5
|
0.161290322580645
|
0.0352112676056338
|
GO:BP
|
GO:0002696
|
positive regulation of leukocyte activation
|
0.000407242250082653
|
412
|
6
|
4
|
0.666666666666667
|
0.00970873786407767
|
GO:BP
|
GO:0050867
|
positive regulation of cell activation
|
0.000422927126081477
|
424
|
6
|
4
|
0.666666666666667
|
0.00943396226415094
|
GO:BP
|
GO:0002697
|
regulation of immune effector process
|
0.000570075196993565
|
461
|
6
|
4
|
0.666666666666667
|
0.00867678958785249
|
GO:BP
|
GO:0002455
|
humoral immune response mediated by circulating immunoglobulin
|
0.000582560858827606
|
156
|
31
|
5
|
0.161290322580645
|
0.032051282051282
|
GO:BP
|
GO:0006911
|
phagocytosis, engulfment
|
0.000594023323897947
|
127
|
6
|
3
|
0.5
|
0.0236220472440945
|
GO:BP
|
GO:0050853
|
B cell receptor signaling pathway
|
0.000686878590976101
|
135
|
6
|
3
|
0.5
|
0.0222222222222222
|
GO:BP
|
GO:0099024
|
plasma membrane invagination
|
0.000686878590976101
|
136
|
6
|
3
|
0.5
|
0.0220588235294118
|
GO:BP
|
GO:1903069
|
regulation of ER-associated ubiquitin-dependent protein catabolic process
|
0.000710719254763076
|
10
|
77
|
3
|
0.038961038961039
|
0.3
|
GO:BP
|
GO:0051249
|
regulation of lymphocyte activation
|
0.000749433084846653
|
518
|
6
|
4
|
0.666666666666667
|
0.00772200772200772
|
GO:BP
|
GO:0010324
|
membrane invagination
|
0.000749433084846653
|
144
|
6
|
3
|
0.5
|
0.0208333333333333
|
GO:BP
|
GO:0006956
|
complement activation
|
0.000928233297655374
|
180
|
31
|
5
|
0.161290322580645
|
0.0277777777777778
|
GO:BP
|
GO:0002694
|
regulation of leukocyte activation
|
0.00129732330598383
|
610
|
6
|
4
|
0.666666666666667
|
0.00655737704918033
|
GO:BP
|
GO:0002252
|
immune effector process
|
0.00148678275462793
|
1309
|
140
|
25
|
0.178571428571429
|
0.0190985485103132
|
GO:BP
|
GO:0044764
|
multi-organism cellular process
|
0.00148678275462793
|
17
|
59
|
3
|
0.0508474576271186
|
0.176470588235294
|
GO:BP
|
GO:0050865
|
regulation of cell activation
|
0.00159884618015841
|
655
|
6
|
4
|
0.666666666666667
|
0.00610687022900763
|
GO:BP
|
GO:0002443
|
leukocyte mediated immunity
|
0.00173737768719628
|
877
|
80
|
14
|
0.175
|
0.015963511972634
|
GO:BP
|
GO:1903034
|
regulation of response to wounding
|
0.00173737768719628
|
169
|
64
|
6
|
0.09375
|
0.0355029585798817
|
GO:BP
|
GO:0016310
|
phosphorylation
|
0.00190023926798509
|
2138
|
96
|
26
|
0.270833333333333
|
0.0121608980355472
|
GO:BP
|
GO:0016064
|
immunoglobulin mediated immune response
|
0.00195073688725818
|
223
|
31
|
5
|
0.161290322580645
|
0.0224215246636771
|
GO:BP
|
GO:0030433
|
ubiquitin-dependent ERAD pathway
|
0.00195073688725818
|
82
|
82
|
5
|
0.0609756097560976
|
0.0609756097560976
|
GO:BP
|
GO:0019724
|
B cell mediated immunity
|
0.00201724235786438
|
226
|
6
|
3
|
0.5
|
0.0132743362831858
|
GO:BP
|
GO:0009617
|
response to bacterium
|
0.00209346638314878
|
743
|
6
|
4
|
0.666666666666667
|
0.0053835800807537
|
GO:BP
|
GO:0008037
|
cell recognition
|
0.00214514705628213
|
235
|
6
|
3
|
0.5
|
0.0127659574468085
|
GO:BP
|
GO:0050778
|
positive regulation of immune response
|
0.00214514705628213
|
753
|
6
|
4
|
0.666666666666667
|
0.00531208499335989
|
GO:BP
|
GO:0006909
|
phagocytosis
|
0.00215105522780648
|
387
|
31
|
6
|
0.193548387096774
|
0.0155038759689922
|
GO:BP
|
GO:0038093
|
Fc receptor signaling pathway
|
0.00215105522780648
|
238
|
6
|
3
|
0.5
|
0.0126050420168067
|
GO:BP
|
GO:0046649
|
lymphocyte activation
|
0.00221660473349302
|
771
|
6
|
4
|
0.666666666666667
|
0.00518806744487678
|
GO:BP
|
GO:1904292
|
regulation of ERAD pathway
|
0.0037049826800935
|
20
|
77
|
3
|
0.038961038961039
|
0.15
|
GO:BP
|
GO:0061041
|
regulation of wound healing
|
0.0037049826800935
|
136
|
59
|
5
|
0.0847457627118644
|
0.0367647058823529
|
GO:BP
|
GO:0002679
|
respiratory burst involved in defense response
|
0.00378456404545635
|
13
|
123
|
3
|
0.024390243902439
|
0.230769230769231
|
GO:BP
|
GO:0045730
|
respiratory burst
|
0.00397272647330756
|
35
|
123
|
4
|
0.032520325203252
|
0.114285714285714
|
GO:BP
|
GO:0051707
|
response to other organism
|
0.00405069823797311
|
1592
|
7
|
5
|
0.714285714285714
|
0.00314070351758794
|
GO:BP
|
GO:0043207
|
response to external biotic stimulus
|
0.00405069823797311
|
1594
|
7
|
5
|
0.714285714285714
|
0.00313676286072773
|
GO:BP
|
GO:0036503
|
ERAD pathway
|
0.00433104799964489
|
103
|
82
|
5
|
0.0609756097560976
|
0.0485436893203883
|
GO:BP
|
GO:0009607
|
response to biotic stimulus
|
0.00433104799964489
|
1626
|
7
|
5
|
0.714285714285714
|
0.0030750307503075
|
GO:BP
|
GO:0050851
|
antigen receptor-mediated signaling pathway
|
0.00442258382772313
|
323
|
6
|
3
|
0.5
|
0.00928792569659443
|
GO:BP
|
GO:0045321
|
leukocyte activation
|
0.00445349430472247
|
1332
|
84
|
17
|
0.202380952380952
|
0.0127627627627628
|
GO:BP
|
GO:0050776
|
regulation of immune response
|
0.00496395759285807
|
996
|
6
|
4
|
0.666666666666667
|
0.00401606425702811
|
GO:BP
|
GO:0042742
|
defense response to bacterium
|
0.00526372945738432
|
349
|
6
|
3
|
0.5
|
0.00859598853868195
|
GO:BP
|
GO:1903036
|
positive regulation of response to wounding
|
0.00526372945738432
|
74
|
64
|
4
|
0.0625
|
0.0540540540540541
|
GO:BP
|
GO:0002449
|
lymphocyte mediated immunity
|
0.00541723102576824
|
354
|
6
|
3
|
0.5
|
0.00847457627118644
|
GO:BP
|
GO:0002460
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
0.00575883998389413
|
363
|
6
|
3
|
0.5
|
0.00826446280991736
|
GO:BP
|
GO:0002684
|
positive regulation of immune system process
|
0.00603161638903793
|
1065
|
6
|
4
|
0.666666666666667
|
0.00375586854460094
|
GO:BP
|
GO:0002407
|
dendritic cell chemotaxis
|
0.00658742486314146
|
24
|
84
|
3
|
0.0357142857142857
|
0.125
|
GO:BP
|
GO:0006959
|
humoral immune response
|
0.00658742486314146
|
384
|
6
|
3
|
0.5
|
0.0078125
|
GO:BP
|
GO:0032434
|
regulation of proteasomal ubiquitin-dependent protein catabolic process
|
0.00900642353033484
|
134
|
77
|
5
|
0.0649350649350649
|
0.0373134328358209
|
GO:BP
|
GO:0006487
|
protein N-linked glycosylation
|
0.00900642353033484
|
76
|
136
|
5
|
0.0367647058823529
|
0.0657894736842105
|
GO:BP
|
GO:0043312
|
neutrophil degranulation
|
0.00900642353033484
|
482
|
135
|
12
|
0.0888888888888889
|
0.024896265560166
|
GO:BP
|
GO:0002283
|
neutrophil activation involved in immune response
|
0.00928193198707055
|
485
|
135
|
12
|
0.0888888888888889
|
0.0247422680412371
|
GO:BP
|
GO:0090316
|
positive regulation of intracellular protein transport
|
0.00957430997462582
|
186
|
57
|
5
|
0.087719298245614
|
0.0268817204301075
|
GO:BP
|
GO:0030512
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
0.0100545887077109
|
88
|
67
|
4
|
0.0597014925373134
|
0.0454545454545455
|
GO:BP
|
GO:0036336
|
dendritic cell migration
|
0.0101530203600341
|
29
|
84
|
3
|
0.0357142857142857
|
0.103448275862069
|
GO:BP
|
GO:0031647
|
regulation of protein stability
|
0.0102374618694186
|
300
|
9
|
3
|
0.333333333333333
|
0.01
|
GO:BP
|
GO:0042119
|
neutrophil activation
|
0.0102374618694186
|
498
|
135
|
12
|
0.0888888888888889
|
0.0240963855421687
|
GO:BP
|
GO:1990748
|
cellular detoxification
|
0.0102374618694186
|
113
|
54
|
4
|
0.0740740740740741
|
0.0353982300884956
|
GO:BP
|
GO:0032436
|
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
|
0.0102374618694186
|
90
|
67
|
4
|
0.0597014925373134
|
0.0444444444444444
|
GO:BP
|
GO:0001959
|
regulation of cytokine-mediated signaling pathway
|
0.0102374618694186
|
184
|
59
|
5
|
0.0847457627118644
|
0.0271739130434783
|
GO:BP
|
GO:0002429
|
immune response-activating cell surface receptor signaling pathway
|
0.0102374618694186
|
477
|
6
|
3
|
0.5
|
0.00628930817610063
|
GO:BP
|
GO:0002446
|
neutrophil mediated immunity
|
0.0102374618694186
|
497
|
135
|
12
|
0.0888888888888889
|
0.0241448692152917
|
GO:BP
|
GO:0002757
|
immune response-activating signal transduction
|
0.0102374618694186
|
477
|
6
|
3
|
0.5
|
0.00628930817610063
|
GO:BP
|
GO:0061024
|
membrane organization
|
0.0102374618694186
|
973
|
19
|
6
|
0.315789473684211
|
0.00616649537512847
|
GO:BP
|
GO:0008219
|
cell death
|
0.0107904689986758
|
2292
|
66
|
19
|
0.287878787878788
|
0.00828970331588133
|
GO:BP
|
GO:0036230
|
granulocyte activation
|
0.0110680786605418
|
504
|
135
|
12
|
0.0888888888888889
|
0.0238095238095238
|
GO:BP
|
GO:0002768
|
immune response-regulating cell surface receptor signaling pathway
|
0.0113976763482991
|
512
|
6
|
3
|
0.5
|
0.005859375
|
GO:BP
|
GO:0002764
|
immune response-regulating signaling pathway
|
0.0114079319362122
|
515
|
6
|
3
|
0.5
|
0.0058252427184466
|
GO:BP
|
GO:0060759
|
regulation of response to cytokine stimulus
|
0.0114079319362122
|
197
|
59
|
5
|
0.0847457627118644
|
0.0253807106598985
|
GO:BP
|
GO:0001775
|
cell activation
|
0.0114079319362122
|
1495
|
84
|
17
|
0.202380952380952
|
0.011371237458194
|
GO:BP
|
GO:0006796
|
phosphate-containing compound metabolic process
|
0.0114079319362122
|
3087
|
96
|
30
|
0.3125
|
0.00971817298347911
|
GO:BP
|
GO:0097237
|
cellular response to toxic substance
|
0.0114079319362122
|
120
|
54
|
4
|
0.0740740740740741
|
0.0333333333333333
|
GO:BP
|
GO:0012501
|
programmed cell death
|
0.0121996876395589
|
2143
|
66
|
18
|
0.272727272727273
|
0.00839944003733084
|
GO:BP
|
GO:0044419
|
biological process involved in interspecies interaction between organisms
|
0.0125345205489196
|
2255
|
7
|
5
|
0.714285714285714
|
0.00221729490022173
|
GO:BP
|
GO:0006793
|
phosphorus metabolic process
|
0.0128165040709198
|
3114
|
71
|
24
|
0.338028169014085
|
0.00770712909441233
|
GO:BP
|
GO:0002253
|
activation of immune response
|
0.0137715193032403
|
568
|
6
|
3
|
0.5
|
0.00528169014084507
|
GO:BP
|
GO:0019725
|
cellular homeostasis
|
0.0140658904923675
|
981
|
64
|
11
|
0.171875
|
0.0112130479102956
|
GO:BP
|
GO:0006915
|
apoptotic process
|
0.0141987897088124
|
1990
|
66
|
17
|
0.257575757575758
|
0.0085427135678392
|
GO:BP
|
GO:0048584
|
positive regulation of response to stimulus
|
0.0142106047076148
|
2344
|
7
|
5
|
0.714285714285714
|
0.00213310580204778
|
GO:BP
|
GO:2000060
|
positive regulation of ubiquitin-dependent protein catabolic process
|
0.0149611018616832
|
107
|
67
|
4
|
0.0597014925373134
|
0.0373831775700935
|
GO:BP
|
GO:0043299
|
leukocyte degranulation
|
0.0149650224523306
|
535
|
135
|
12
|
0.0888888888888889
|
0.0224299065420561
|
GO:BP
|
GO:0032388
|
positive regulation of intracellular transport
|
0.0149966935259567
|
229
|
32
|
4
|
0.125
|
0.0174672489082969
|
GO:BP
|
GO:0098754
|
detoxification
|
0.0149966935259567
|
134
|
54
|
4
|
0.0740740740740741
|
0.0298507462686567
|
GO:BP
|
GO:2000058
|
regulation of ubiquitin-dependent protein catabolic process
|
0.0150181623155044
|
165
|
77
|
5
|
0.0649350649350649
|
0.0303030303030303
|
GO:BP
|
GO:0097190
|
apoptotic signaling pathway
|
0.0150181623155044
|
600
|
59
|
8
|
0.135593220338983
|
0.0133333333333333
|
GO:BP
|
GO:0090303
|
positive regulation of wound healing
|
0.016385569044724
|
60
|
54
|
3
|
0.0555555555555556
|
0.05
|
GO:BP
|
GO:1901800
|
positive regulation of proteasomal protein catabolic process
|
0.0168309116133641
|
112
|
67
|
4
|
0.0597014925373134
|
0.0357142857142857
|
GO:BP
|
GO:0002275
|
myeloid cell activation involved in immune response
|
0.0171023765153472
|
547
|
135
|
12
|
0.0888888888888889
|
0.0219378427787934
|
GO:BP
|
GO:0002682
|
regulation of immune system process
|
0.0171410647076109
|
1617
|
6
|
4
|
0.666666666666667
|
0.00247371675943105
|
GO:BP
|
GO:0009896
|
positive regulation of catabolic process
|
0.0176543354789911
|
464
|
8
|
3
|
0.375
|
0.00646551724137931
|
GO:BP
|
GO:0002444
|
myeloid leukocyte mediated immunity
|
0.017810015366997
|
551
|
135
|
12
|
0.0888888888888889
|
0.0217785843920145
|
GO:BP
|
GO:0033157
|
regulation of intracellular protein transport
|
0.0183748371119084
|
264
|
77
|
6
|
0.0779220779220779
|
0.0227272727272727
|
GO:BP
|
GO:0071345
|
cellular response to cytokine stimulus
|
0.0184391258947826
|
1132
|
4
|
3
|
0.75
|
0.00265017667844523
|
GO:BP
|
GO:0002366
|
leukocyte activation involved in immune response
|
0.0184391258947826
|
717
|
135
|
14
|
0.103703703703704
|
0.0195258019525802
|
GO:BP
|
GO:0002263
|
cell activation involved in immune response
|
0.0188116780133055
|
721
|
135
|
14
|
0.103703703703704
|
0.0194174757281553
|
GO:BP
|
GO:0018279
|
protein N-linked glycosylation via asparagine
|
0.0188116780133055
|
30
|
120
|
3
|
0.025
|
0.1
|
GO:BP
|
GO:0002250
|
adaptive immune response
|
0.0188116780133055
|
689
|
6
|
3
|
0.5
|
0.00435413642960813
|
GO:BP
|
GO:0006897
|
endocytosis
|
0.0191575025451254
|
696
|
6
|
3
|
0.5
|
0.00431034482758621
|
GO:BP
|
GO:0048878
|
chemical homeostasis
|
0.0199128439090372
|
1229
|
64
|
12
|
0.1875
|
0.00976403580146461
|
GO:BP
|
GO:0018196
|
peptidyl-asparagine modification
|
0.0199498337895034
|
31
|
120
|
3
|
0.025
|
0.0967741935483871
|
GO:BP
|
GO:2001233
|
regulation of apoptotic signaling pathway
|
0.0203751775414576
|
363
|
59
|
6
|
0.101694915254237
|
0.0165289256198347
|
GO:BP
|
GO:0034097
|
response to cytokine
|
0.0206785089386244
|
1226
|
4
|
3
|
0.75
|
0.00244698205546493
|
GO:BP
|
GO:0061136
|
regulation of proteasomal protein catabolic process
|
0.0206785089386244
|
186
|
77
|
5
|
0.0649350649350649
|
0.0268817204301075
|
GO:BP
|
GO:0033344
|
cholesterol efflux
|
0.0221607723011007
|
66
|
59
|
3
|
0.0508474576271186
|
0.0454545454545455
|
GO:BP
|
GO:0017015
|
regulation of transforming growth factor beta receptor signaling pathway
|
0.0224381067798864
|
129
|
67
|
4
|
0.0597014925373134
|
0.0310077519379845
|
GO:BP
|
GO:0030193
|
regulation of blood coagulation
|
0.0232715255433993
|
68
|
59
|
3
|
0.0508474576271186
|
0.0441176470588235
|
GO:BP
|
GO:1903362
|
regulation of cellular protein catabolic process
|
0.0232715255433993
|
257
|
86
|
6
|
0.0697674418604651
|
0.0233463035019455
|
GO:BP
|
GO:1903052
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
0.0232715255433993
|
131
|
67
|
4
|
0.0597014925373134
|
0.0305343511450382
|
GO:BP
|
GO:0030162
|
regulation of proteolysis
|
0.0232715255433993
|
752
|
78
|
10
|
0.128205128205128
|
0.0132978723404255
|
GO:BP
|
GO:1903844
|
regulation of cellular response to transforming growth factor beta stimulus
|
0.0235901854933287
|
132
|
67
|
4
|
0.0597014925373134
|
0.0303030303030303
|
GO:BP
|
GO:0006383
|
transcription by RNA polymerase III
|
0.0237817037367305
|
48
|
85
|
3
|
0.0352941176470588
|
0.0625
|
GO:BP
|
GO:1900046
|
regulation of hemostasis
|
0.0237817037367305
|
69
|
59
|
3
|
0.0508474576271186
|
0.0434782608695652
|
GO:BP
|
GO:2001236
|
regulation of extrinsic apoptotic signaling pathway
|
0.0237817037367305
|
159
|
140
|
6
|
0.0428571428571429
|
0.0377358490566038
|
GO:BP
|
GO:0048145
|
regulation of fibroblast proliferation
|
0.0248126592991004
|
87
|
48
|
3
|
0.0625
|
0.0344827586206897
|
GO:BP
|
GO:0090101
|
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
|
0.0250455507902649
|
136
|
67
|
4
|
0.0597014925373134
|
0.0294117647058824
|
GO:BP
|
GO:0048144
|
fibroblast proliferation
|
0.0252273106224078
|
88
|
48
|
3
|
0.0625
|
0.0340909090909091
|
GO:BP
|
GO:0009605
|
response to external stimulus
|
0.0270970126671973
|
2944
|
7
|
5
|
0.714285714285714
|
0.00169836956521739
|
GO:BP
|
GO:0045732
|
positive regulation of protein catabolic process
|
0.0278439661954812
|
237
|
67
|
5
|
0.0746268656716418
|
0.0210970464135021
|
GO:BP
|
GO:0050818
|
regulation of coagulation
|
0.0280304536209854
|
75
|
59
|
3
|
0.0508474576271186
|
0.04
|
GO:BP
|
GO:1904951
|
positive regulation of establishment of protein localization
|
0.0285017774981913
|
345
|
69
|
6
|
0.0869565217391304
|
0.0173913043478261
|
GO:BP
|
GO:0048147
|
negative regulation of fibroblast proliferation
|
0.0291974437042975
|
34
|
136
|
3
|
0.0220588235294118
|
0.0882352941176471
|
GO:BP
|
GO:0006040
|
amino sugar metabolic process
|
0.0299814924022288
|
42
|
112
|
3
|
0.0267857142857143
|
0.0714285714285714
|
GO:BP
|
GO:0045055
|
regulated exocytosis
|
0.0299814924022288
|
785
|
135
|
14
|
0.103703703703704
|
0.0178343949044586
|
GO:BP
|
GO:0001960
|
negative regulation of cytokine-mediated signaling pathway
|
0.0319360222626535
|
82
|
59
|
3
|
0.0508474576271186
|
0.0365853658536585
|
GO:BP
|
GO:1903050
|
regulation of proteolysis involved in cellular protein catabolic process
|
0.0327746081799893
|
221
|
77
|
5
|
0.0649350649350649
|
0.0226244343891403
|
GO:BP
|
GO:1903364
|
positive regulation of cellular protein catabolic process
|
0.0329736642774117
|
154
|
67
|
4
|
0.0597014925373134
|
0.025974025974026
|
GO:BP
|
GO:0051222
|
positive regulation of protein transport
|
0.0332198337696762
|
329
|
32
|
4
|
0.125
|
0.0121580547112462
|
GO:BP
|
GO:0055082
|
cellular chemical homeostasis
|
0.0340149434022918
|
841
|
64
|
9
|
0.140625
|
0.0107015457788347
|
GO:BP
|
GO:0045862
|
positive regulation of proteolysis
|
0.034408463504419
|
378
|
67
|
6
|
0.0895522388059701
|
0.0158730158730159
|
GO:BP
|
GO:0000041
|
transition metal ion transport
|
0.034514261290211
|
129
|
135
|
5
|
0.037037037037037
|
0.0387596899224806
|
GO:BP
|
GO:0042176
|
regulation of protein catabolic process
|
0.0358382635172338
|
401
|
86
|
7
|
0.0813953488372093
|
0.0174563591022444
|
GO:BP
|
GO:0060761
|
negative regulation of response to cytokine stimulus
|
0.0358382635172338
|
88
|
59
|
3
|
0.0508474576271186
|
0.0340909090909091
|
GO:BP
|
GO:0045087
|
innate immune response
|
0.0358382635172338
|
998
|
6
|
3
|
0.5
|
0.0030060120240481
|
GO:BP
|
GO:0006826
|
iron ion transport
|
0.036144340207961
|
80
|
135
|
4
|
0.0296296296296296
|
0.05
|
GO:BP
|
GO:0006955
|
immune response
|
0.036475708221407
|
2311
|
135
|
29
|
0.214814814814815
|
0.0125486802250108
|
GO:BP
|
GO:0010941
|
regulation of cell death
|
0.0366558970627764
|
1720
|
66
|
14
|
0.212121212121212
|
0.00813953488372093
|
GO:BP
|
GO:0032101
|
regulation of response to external stimulus
|
0.0370530769576663
|
1051
|
84
|
12
|
0.142857142857143
|
0.0114176974310181
|
GO:BP
|
GO:0042592
|
homeostatic process
|
0.0370530769576663
|
1981
|
64
|
15
|
0.234375
|
0.00757193336698637
|
GO:BP
|
GO:0060548
|
negative regulation of cell death
|
0.0370725163610056
|
1038
|
64
|
10
|
0.15625
|
0.00963391136801541
|
GO:BP
|
GO:2001235
|
positive regulation of apoptotic signaling pathway
|
0.0370725163610056
|
129
|
140
|
5
|
0.0357142857142857
|
0.0387596899224806
|
GO:BP
|
GO:0098869
|
cellular oxidant detoxification
|
0.0370725163610056
|
100
|
54
|
3
|
0.0555555555555556
|
0.03
|
GO:BP
|
GO:0019221
|
cytokine-mediated signaling pathway
|
0.0395898879505443
|
810
|
24
|
5
|
0.208333333333333
|
0.00617283950617284
|
GO:BP
|
GO:0032386
|
regulation of intracellular transport
|
0.040135864502397
|
367
|
32
|
4
|
0.125
|
0.0108991825613079
|
GO:BP
|
GO:0120162
|
positive regulation of cold-induced thermogenesis
|
0.0409156367086982
|
97
|
59
|
3
|
0.0508474576271186
|
0.0309278350515464
|
GO:BP
|
GO:0002274
|
myeloid leukocyte activation
|
0.0421926833521312
|
667
|
135
|
12
|
0.0888888888888889
|
0.0179910044977511
|
GO:BP
|
GO:0043067
|
regulation of programmed cell death
|
0.0421926833521312
|
1582
|
66
|
13
|
0.196969696969697
|
0.00821744627054362
|
GO:BP
|
GO:0009615
|
response to virus
|
0.0421926833521312
|
364
|
33
|
4
|
0.121212121212121
|
0.010989010989011
|
GO:BP
|
GO:1905897
|
regulation of response to endoplasmic reticulum stress
|
0.0421926833521312
|
84
|
140
|
4
|
0.0285714285714286
|
0.0476190476190476
|
GO:BP
|
GO:0055092
|
sterol homeostasis
|
0.0421926833521312
|
100
|
59
|
3
|
0.0508474576271186
|
0.03
|
GO:BP
|
GO:0042632
|
cholesterol homeostasis
|
0.0421926833521312
|
99
|
59
|
3
|
0.0508474576271186
|
0.0303030303030303
|
GO:BP
|
GO:0045454
|
cell redox homeostasis
|
0.0430232888017289
|
58
|
103
|
3
|
0.029126213592233
|
0.0517241379310345
|
GO:BP
|
GO:0002532
|
production of molecular mediator involved in inflammatory response
|
0.0436030697629886
|
94
|
64
|
3
|
0.046875
|
0.0319148936170213
|
GO:BP
|
GO:0043933
|
protein-containing complex subunit organization
|
0.0447550856219708
|
1963
|
93
|
19
|
0.204301075268817
|
0.00967906265919511
|
GO:BP
|
GO:0043066
|
negative regulation of apoptotic process
|
0.0458623635890617
|
921
|
64
|
9
|
0.140625
|
0.00977198697068404
|
GO:BP
|
GO:0044409
|
entry into host
|
0.0458623635890617
|
154
|
80
|
4
|
0.05
|
0.025974025974026
|
GO:BP
|
GO:0065003
|
protein-containing complex assembly
|
0.0460558008950708
|
1680
|
93
|
17
|
0.182795698924731
|
0.0101190476190476
|
GO:BP
|
GO:0006979
|
response to oxidative stress
|
0.0473103997384636
|
466
|
103
|
8
|
0.0776699029126214
|
0.0171673819742489
|
GO:BP
|
GO:0098542
|
defense response to other organism
|
0.0476944390017553
|
1218
|
6
|
3
|
0.5
|
0.00246305418719212
|
GO:BP
|
GO:2001238
|
positive regulation of extrinsic apoptotic signaling pathway
|
0.0482197399352134
|
48
|
134
|
3
|
0.0223880597014925
|
0.0625
|
GO:BP
|
GO:1903573
|
negative regulation of response to endoplasmic reticulum stress
|
0.0482197399352134
|
46
|
140
|
3
|
0.0214285714285714
|
0.0652173913043478
|
GO:BP
|
GO:0031668
|
cellular response to extracellular stimulus
|
0.0497413477659744
|
248
|
83
|
5
|
0.0602409638554217
|
0.0201612903225806
|
GO:BP
|
GO:0043069
|
negative regulation of programmed cell death
|
0.0498064933527588
|
943
|
64
|
9
|
0.140625
|
0.0095440084835631
|
GO:CC
|
GO:0070469
|
respirasome
|
1.1294043367694e-12
|
103
|
93
|
13
|
0.139784946236559
|
0.12621359223301
|
GO:CC
|
GO:0005746
|
mitochondrial respirasome
|
1.08804750799117e-10
|
89
|
93
|
11
|
0.118279569892473
|
0.123595505617978
|
GO:CC
|
GO:0005747
|
mitochondrial respiratory chain complex I
|
2.15325498246428e-10
|
51
|
93
|
9
|
0.0967741935483871
|
0.176470588235294
|
GO:CC
|
GO:0045271
|
respiratory chain complex I
|
2.15325498246428e-10
|
51
|
93
|
9
|
0.0967741935483871
|
0.176470588235294
|
GO:CC
|
GO:0030964
|
NADH dehydrogenase complex
|
2.15325498246428e-10
|
51
|
93
|
9
|
0.0967741935483871
|
0.176470588235294
|
GO:CC
|
GO:0098800
|
inner mitochondrial membrane protein complex
|
4.24331223593943e-10
|
146
|
93
|
12
|
0.129032258064516
|
0.0821917808219178
|
GO:CC
|
GO:0098803
|
respiratory chain complex
|
6.92926653238166e-10
|
86
|
93
|
10
|
0.10752688172043
|
0.116279069767442
|
GO:CC
|
GO:1990204
|
oxidoreductase complex
|
1.22541731246872e-09
|
113
|
103
|
11
|
0.106796116504854
|
0.0973451327433628
|
GO:CC
|
GO:0005743
|
mitochondrial inner membrane
|
2.22224910931282e-09
|
503
|
95
|
18
|
0.189473684210526
|
0.0357852882703777
|
GO:CC
|
GO:0019866
|
organelle inner membrane
|
1.27696876917141e-08
|
564
|
95
|
18
|
0.189473684210526
|
0.0319148936170213
|
GO:CC
|
GO:0031966
|
mitochondrial membrane
|
1.90585588666551e-08
|
746
|
104
|
21
|
0.201923076923077
|
0.0281501340482574
|
GO:CC
|
GO:0098798
|
mitochondrial protein-containing complex
|
2.20709926525832e-08
|
270
|
93
|
13
|
0.139784946236559
|
0.0481481481481481
|
GO:CC
|
GO:0005740
|
mitochondrial envelope
|
5.28295991517828e-08
|
797
|
104
|
21
|
0.201923076923077
|
0.0263488080301129
|
GO:CC
|
GO:0005739
|
mitochondrion
|
2.93669220137055e-07
|
1673
|
97
|
28
|
0.288659793814433
|
0.0167364016736402
|
GO:CC
|
GO:0031090
|
organelle membrane
|
1.39746888421845e-06
|
3612
|
140
|
54
|
0.385714285714286
|
0.0149501661129568
|
GO:CC
|
GO:0031975
|
envelope
|
3.18841665292344e-06
|
1237
|
95
|
22
|
0.231578947368421
|
0.0177849636216653
|
GO:CC
|
GO:0031967
|
organelle envelope
|
3.18841665292344e-06
|
1237
|
95
|
22
|
0.231578947368421
|
0.0177849636216653
|
GO:CC
|
GO:0042571
|
immunoglobulin complex, circulating
|
2.68841662428241e-05
|
77
|
6
|
3
|
0.5
|
0.038961038961039
|
GO:CC
|
GO:0005773
|
vacuole
|
9.4821911142348e-05
|
810
|
135
|
19
|
0.140740740740741
|
0.0234567901234568
|
GO:CC
|
GO:0019814
|
immunoglobulin complex
|
0.000133556248048331
|
167
|
31
|
5
|
0.161290322580645
|
0.029940119760479
|
GO:CC
|
GO:0072562
|
blood microparticle
|
0.000139941585580747
|
140
|
6
|
3
|
0.5
|
0.0214285714285714
|
GO:CC
|
GO:0070062
|
extracellular exosome
|
0.000174751114311278
|
2176
|
82
|
24
|
0.292682926829268
|
0.0110294117647059
|
GO:CC
|
GO:0005766
|
primary lysosome
|
0.000231029923231246
|
154
|
135
|
8
|
0.0592592592592593
|
0.051948051948052
|
GO:CC
|
GO:0042582
|
azurophil granule
|
0.000231029923231246
|
154
|
135
|
8
|
0.0592592592592593
|
0.051948051948052
|
GO:CC
|
GO:0043230
|
extracellular organelle
|
0.000286767063571186
|
2263
|
82
|
24
|
0.292682926829268
|
0.0106053910737958
|
GO:CC
|
GO:1903561
|
extracellular vesicle
|
0.000286767063571186
|
2261
|
82
|
24
|
0.292682926829268
|
0.0106147722246793
|
GO:CC
|
GO:0016020
|
membrane
|
0.000596038123739369
|
9838
|
140
|
96
|
0.685714285714286
|
0.00975808091075422
|
GO:CC
|
GO:0000323
|
lytic vacuole
|
0.000596038123739369
|
712
|
135
|
16
|
0.118518518518519
|
0.0224719101123595
|
GO:CC
|
GO:0005764
|
lysosome
|
0.000596038123739369
|
712
|
135
|
16
|
0.118518518518519
|
0.0224719101123595
|
GO:CC
|
GO:0035578
|
azurophil granule lumen
|
0.000596038123739369
|
91
|
135
|
6
|
0.0444444444444444
|
0.0659340659340659
|
GO:CC
|
GO:1902494
|
catalytic complex
|
0.000961952149030021
|
1441
|
103
|
20
|
0.194174757281553
|
0.0138792505204719
|
GO:CC
|
GO:0098796
|
membrane protein complex
|
0.00185844972307777
|
1322
|
83
|
16
|
0.192771084337349
|
0.0121028744326778
|
GO:CC
|
GO:0031300
|
intrinsic component of organelle membrane
|
0.00185844972307777
|
413
|
112
|
10
|
0.0892857142857143
|
0.0242130750605327
|
GO:CC
|
GO:0009897
|
external side of plasma membrane
|
0.00193098402993405
|
408
|
6
|
3
|
0.5
|
0.00735294117647059
|
GO:CC
|
GO:0005767
|
secondary lysosome
|
0.00193098402993405
|
16
|
135
|
3
|
0.0222222222222222
|
0.1875
|
GO:CC
|
GO:0005783
|
endoplasmic reticulum
|
0.00241458331293561
|
1982
|
140
|
29
|
0.207142857142857
|
0.0146316851664985
|
GO:CC
|
GO:0005775
|
vacuolar lumen
|
0.00243932539559835
|
174
|
135
|
7
|
0.0518518518518519
|
0.0402298850574713
|
GO:CC
|
GO:0031224
|
intrinsic component of membrane
|
0.00258671158334884
|
5868
|
108
|
51
|
0.472222222222222
|
0.00869120654396728
|
GO:CC
|
GO:0016021
|
integral component of membrane
|
0.00258671158334884
|
5711
|
108
|
50
|
0.462962962962963
|
0.00875503414463316
|
GO:CC
|
GO:0005615
|
extracellular space
|
0.00300474452376226
|
3594
|
82
|
29
|
0.353658536585366
|
0.00806900389538119
|
GO:CC
|
GO:0031227
|
intrinsic component of endoplasmic reticulum membrane
|
0.00300474452376226
|
166
|
106
|
6
|
0.0566037735849057
|
0.036144578313253
|
GO:CC
|
GO:0005737
|
cytoplasm
|
0.00402251443142639
|
11911
|
126
|
97
|
0.76984126984127
|
0.00814373268407355
|
GO:CC
|
GO:0034774
|
secretory granule lumen
|
0.00407009907035496
|
320
|
135
|
9
|
0.0666666666666667
|
0.028125
|
GO:CC
|
GO:0060205
|
cytoplasmic vesicle lumen
|
0.0043539473411422
|
324
|
135
|
9
|
0.0666666666666667
|
0.0277777777777778
|
GO:CC
|
GO:0031983
|
vesicle lumen
|
0.00445374619842401
|
326
|
135
|
9
|
0.0666666666666667
|
0.0276073619631902
|
GO:CC
|
GO:0098552
|
side of membrane
|
0.00507987577584083
|
619
|
6
|
3
|
0.5
|
0.00484652665589661
|
GO:CC
|
GO:0009986
|
cell surface
|
0.006896152168397
|
899
|
17
|
5
|
0.294117647058824
|
0.00556173526140156
|
GO:CC
|
GO:0031301
|
integral component of organelle membrane
|
0.00792072667762207
|
382
|
102
|
8
|
0.0784313725490196
|
0.0209424083769634
|
GO:CC
|
GO:0031982
|
vesicle
|
0.00833554110579703
|
4055
|
82
|
30
|
0.365853658536585
|
0.00739827373612824
|
GO:CC
|
GO:0043227
|
membrane-bounded organelle
|
0.0100621069188846
|
12858
|
126
|
101
|
0.801587301587302
|
0.0078550318867631
|
GO:CC
|
GO:0030176
|
integral component of endoplasmic reticulum membrane
|
0.0115150336846944
|
158
|
102
|
5
|
0.0490196078431373
|
0.0316455696202532
|
GO:CC
|
GO:0012505
|
endomembrane system
|
0.0128618512026517
|
4640
|
140
|
50
|
0.357142857142857
|
0.0107758620689655
|
GO:CC
|
GO:0031984
|
organelle subcompartment
|
0.0130331639195375
|
1773
|
137
|
24
|
0.175182481751825
|
0.0135363790186125
|
GO:CC
|
GO:0030141
|
secretory granule
|
0.0193433011513139
|
851
|
135
|
14
|
0.103703703703704
|
0.0164512338425382
|
GO:CC
|
GO:0005576
|
extracellular region
|
0.0229860665684325
|
4567
|
56
|
23
|
0.410714285714286
|
0.0050361287497263
|
GO:CC
|
GO:0070820
|
tertiary granule
|
0.028482873920101
|
163
|
78
|
4
|
0.0512820512820513
|
0.0245398773006135
|
GO:CC
|
GO:0005776
|
autophagosome
|
0.0318781332151241
|
98
|
135
|
4
|
0.0296296296296296
|
0.0408163265306122
|
GO:CC
|
GO:0005789
|
endoplasmic reticulum membrane
|
0.0344602100935179
|
1117
|
123
|
15
|
0.121951219512195
|
0.0134288272157565
|
GO:CC
|
GO:0043231
|
intracellular membrane-bounded organelle
|
0.0347836798318765
|
11296
|
112
|
80
|
0.714285714285714
|
0.00708215297450425
|
GO:CC
|
GO:0098827
|
endoplasmic reticulum subcompartment
|
0.0347836798318765
|
1122
|
123
|
15
|
0.121951219512195
|
0.0133689839572193
|
GO:CC
|
GO:0042175
|
nuclear outer membrane-endoplasmic reticulum membrane network
|
0.0384922799521658
|
1139
|
123
|
15
|
0.121951219512195
|
0.0131694468832309
|
GO:CC
|
GO:0101002
|
ficolin-1-rich granule
|
0.0384922799521658
|
184
|
78
|
4
|
0.0512820512820513
|
0.0217391304347826
|
GO:CC
|
GO:0005759
|
mitochondrial matrix
|
0.0395553177934489
|
479
|
89
|
7
|
0.0786516853932584
|
0.0146137787056367
|
GO:CC
|
GO:0099503
|
secretory vesicle
|
0.0449714606523493
|
1020
|
140
|
15
|
0.107142857142857
|
0.0147058823529412
|
GO:MF
|
GO:0009055
|
electron transfer activity
|
4.10263971171753e-09
|
148
|
93
|
12
|
0.129032258064516
|
0.0810810810810811
|
GO:MF
|
GO:0003954
|
NADH dehydrogenase activity
|
3.01326557266887e-07
|
46
|
93
|
7
|
0.0752688172043011
|
0.152173913043478
|
GO:MF
|
GO:0008137
|
NADH dehydrogenase (ubiquinone) activity
|
3.01326557266887e-07
|
46
|
93
|
7
|
0.0752688172043011
|
0.152173913043478
|
GO:MF
|
GO:0050136
|
NADH dehydrogenase (quinone) activity
|
3.01326557266887e-07
|
46
|
93
|
7
|
0.0752688172043011
|
0.152173913043478
|
GO:MF
|
GO:0003955
|
NAD(P)H dehydrogenase (quinone) activity
|
3.82217859567753e-07
|
49
|
93
|
7
|
0.0752688172043011
|
0.142857142857143
|
GO:MF
|
GO:0016655
|
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
|
1.54119980709345e-06
|
61
|
93
|
7
|
0.0752688172043011
|
0.114754098360656
|
GO:MF
|
GO:0016651
|
oxidoreductase activity, acting on NAD(P)H
|
8.42843200055265e-06
|
107
|
103
|
8
|
0.0776699029126214
|
0.0747663551401869
|
GO:MF
|
GO:0016491
|
oxidoreductase activity
|
1.10401278062329e-05
|
771
|
103
|
18
|
0.174757281553398
|
0.0233463035019455
|
GO:MF
|
GO:0034987
|
immunoglobulin receptor binding
|
7.00998316771496e-05
|
79
|
6
|
3
|
0.5
|
0.0379746835443038
|
GO:MF
|
GO:0003823
|
antigen binding
|
0.000294314589774927
|
163
|
31
|
5
|
0.161290322580645
|
0.0306748466257669
|
GO:MF
|
GO:0032934
|
sterol binding
|
0.0102264642020725
|
60
|
106
|
4
|
0.0377358490566038
|
0.0666666666666667
|
GO:MF
|
GO:0004601
|
peroxidase activity
|
0.0118134499653497
|
53
|
54
|
3
|
0.0555555555555556
|
0.0566037735849057
|
GO:MF
|
GO:0016684
|
oxidoreductase activity, acting on peroxide as acceptor
|
0.0137697724978345
|
57
|
54
|
3
|
0.0555555555555556
|
0.0526315789473684
|
GO:MF
|
GO:0008198
|
ferrous iron binding
|
0.0168898761846873
|
26
|
135
|
3
|
0.0222222222222222
|
0.115384615384615
|
GO:MF
|
GO:0005102
|
signaling receptor binding
|
0.0168898761846873
|
1672
|
6
|
4
|
0.666666666666667
|
0.00239234449760766
|
GO:MF
|
GO:0004869
|
cysteine-type endopeptidase inhibitor activity
|
0.0213939427730924
|
52
|
78
|
3
|
0.0384615384615385
|
0.0576923076923077
|
GO:MF
|
GO:0016209
|
antioxidant activity
|
0.0254733106672568
|
87
|
54
|
3
|
0.0555555555555556
|
0.0344827586206897
|
GO:MF
|
GO:0005496
|
steroid binding
|
0.0270286480781038
|
100
|
106
|
4
|
0.0377358490566038
|
0.04
|
GO:MF
|
GO:0043028
|
cysteine-type endopeptidase regulator activity involved in apoptotic process
|
0.0270286480781038
|
38
|
134
|
3
|
0.0223880597014925
|
0.0789473684210526
|
GO:MF
|
GO:0015485
|
cholesterol binding
|
0.0298594610517934
|
50
|
106
|
3
|
0.0283018867924528
|
0.06
|
GO:MF
|
GO:0051536
|
iron-sulfur cluster binding
|
0.0402698434535775
|
70
|
87
|
3
|
0.0344827586206897
|
0.0428571428571429
|
GO:MF
|
GO:0051540
|
metal cluster binding
|
0.0402698434535775
|
70
|
87
|
3
|
0.0344827586206897
|
0.0428571428571429
|
GO:MF
|
GO:0019901
|
protein kinase binding
|
0.043982572510103
|
673
|
59
|
7
|
0.11864406779661
|
0.0104011887072808
|
GO:MF
|
GO:0019900
|
kinase binding
|
0.0441854645640512
|
752
|
96
|
10
|
0.104166666666667
|
0.0132978723404255
|
KEGG
|
KEGG:04932
|
Non-alcoholic fatty liver disease
|
2.23002028649881e-07
|
150
|
93
|
14
|
0.150537634408602
|
0.0933333333333333
|
KEGG
|
KEGG:00190
|
Oxidative phosphorylation
|
1.83907511997201e-06
|
133
|
109
|
13
|
0.119266055045872
|
0.0977443609022556
|
KEGG
|
KEGG:04714
|
Thermogenesis
|
1.93322879891432e-05
|
232
|
93
|
14
|
0.150537634408602
|
0.0603448275862069
|
KEGG
|
KEGG:05415
|
Diabetic cardiomyopathy
|
6.58441594663412e-05
|
203
|
103
|
13
|
0.12621359223301
|
0.0640394088669951
|
KEGG
|
KEGG:05012
|
Parkinson disease
|
0.000151627817485038
|
249
|
79
|
12
|
0.151898734177215
|
0.0481927710843374
|
KEGG
|
KEGG:04723
|
Retrograde endocannabinoid signaling
|
0.000186783202341015
|
148
|
93
|
10
|
0.10752688172043
|
0.0675675675675676
|
KEGG
|
KEGG:05020
|
Prion disease
|
0.000199496796828369
|
273
|
103
|
14
|
0.135922330097087
|
0.0512820512820513
|
KEGG
|
KEGG:05016
|
Huntington disease
|
0.000754112064173294
|
306
|
79
|
12
|
0.151898734177215
|
0.0392156862745098
|
KEGG
|
KEGG:05014
|
Amyotrophic lateral sclerosis
|
0.000799238075189995
|
363
|
79
|
13
|
0.164556962025316
|
0.0358126721763085
|
KEGG
|
KEGG:05010
|
Alzheimer disease
|
0.003595733740519
|
369
|
79
|
12
|
0.151898734177215
|
0.032520325203252
|
KEGG
|
KEGG:05022
|
Pathways of neurodegeneration - multiple diseases
|
0.0303445040537227
|
475
|
79
|
12
|
0.151898734177215
|
0.0252631578947368
|
MIRNA
|
MIRNA:hsa-miR-4763-3p
|
hsa-miR-4763-3p
|
0.0360797078105338
|
282
|
36
|
6
|
0.166666666666667
|
0.0212765957446809
|
MIRNA
|
MIRNA:hsa-miR-1207-5p
|
hsa-miR-1207-5p
|
0.0360797078105338
|
287
|
36
|
6
|
0.166666666666667
|
0.0209059233449477
|
REAC
|
REAC:R-HSA-611105
|
Respiratory electron transport
|
2.79225632309801e-08
|
100
|
93
|
12
|
0.129032258064516
|
0.12
|
REAC
|
REAC:R-HSA-6799198
|
Complex I biogenesis
|
1.54957575719896e-07
|
55
|
93
|
9
|
0.0967741935483871
|
0.163636363636364
|
REAC
|
REAC:R-HSA-163200
|
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
|
1.54957575719896e-07
|
124
|
93
|
12
|
0.129032258064516
|
0.0967741935483871
|
REAC
|
REAC:R-HSA-1428517
|
The citric acid (TCA) cycle and respiratory electron transport
|
4.26668731511239e-06
|
174
|
93
|
12
|
0.129032258064516
|
0.0689655172413793
|
REAC
|
REAC:R-HSA-173623
|
Classical antibody-mediated complement activation
|
7.77389313188802e-05
|
61
|
31
|
5
|
0.161290322580645
|
0.0819672131147541
|
REAC
|
REAC:R-HSA-2029481
|
FCGR activation
|
9.59026718543789e-05
|
67
|
31
|
5
|
0.161290322580645
|
0.0746268656716418
|
REAC
|
REAC:R-HSA-166786
|
Creation of C4 and C2 activators
|
9.59026718543789e-05
|
68
|
31
|
5
|
0.161290322580645
|
0.0735294117647059
|
REAC
|
REAC:R-HSA-166663
|
Initial triggering of complement
|
0.000146291397982498
|
76
|
31
|
5
|
0.161290322580645
|
0.0657894736842105
|
REAC
|
REAC:R-HSA-2029485
|
Role of phospholipids in phagocytosis
|
0.000178490705990469
|
81
|
31
|
5
|
0.161290322580645
|
0.0617283950617284
|
REAC
|
REAC:R-HSA-9664323
|
FCGR3A-mediated IL10 synthesis
|
0.000317885575757101
|
93
|
31
|
5
|
0.161290322580645
|
0.0537634408602151
|
REAC
|
REAC:R-HSA-977606
|
Regulation of Complement cascade
|
0.000433234882591754
|
101
|
31
|
5
|
0.161290322580645
|
0.0495049504950495
|
REAC
|
REAC:R-HSA-9664417
|
Leishmania phagocytosis
|
0.000549237840685757
|
113
|
31
|
5
|
0.161290322580645
|
0.0442477876106195
|
REAC
|
REAC:R-HSA-9664407
|
Parasite infection
|
0.000549237840685757
|
113
|
31
|
5
|
0.161290322580645
|
0.0442477876106195
|
REAC
|
REAC:R-HSA-9664422
|
FCGR3A-mediated phagocytosis
|
0.000549237840685757
|
113
|
31
|
5
|
0.161290322580645
|
0.0442477876106195
|
REAC
|
REAC:R-HSA-166658
|
Complement cascade
|
0.000549237840685757
|
111
|
31
|
5
|
0.161290322580645
|
0.045045045045045
|
REAC
|
REAC:R-HSA-2029482
|
Regulation of actin dynamics for phagocytic cup formation
|
0.000584739878301132
|
116
|
31
|
5
|
0.161290322580645
|
0.0431034482758621
|
REAC
|
REAC:R-HSA-2029480
|
Fcgamma receptor (FCGR) dependent phagocytosis
|
0.00122552929830946
|
140
|
6
|
3
|
0.5
|
0.0214285714285714
|
REAC
|
REAC:R-HSA-9662851
|
Anti-inflammatory response favouring Leishmania parasite infection
|
0.00427231401780351
|
221
|
6
|
3
|
0.5
|
0.0135746606334842
|
REAC
|
REAC:R-HSA-9664433
|
Leishmania parasite growth and survival
|
0.00427231401780351
|
221
|
6
|
3
|
0.5
|
0.0135746606334842
|
REAC
|
REAC:R-HSA-3299685
|
Detoxification of Reactive Oxygen Species
|
0.00758204353157462
|
35
|
103
|
4
|
0.0388349514563107
|
0.114285714285714
|
REAC
|
REAC:R-HSA-9711123
|
Cellular response to chemical stress
|
0.00758204353157462
|
35
|
103
|
4
|
0.0388349514563107
|
0.114285714285714
|
REAC
|
REAC:R-HSA-9658195
|
Leishmania infection
|
0.00896850735181939
|
303
|
6
|
3
|
0.5
|
0.0099009900990099
|
TF
|
TF:M10435_1
|
Factor: Sp2; motif: GGGGCGGGG; match class: 1
|
0.00878435847323308
|
3495
|
125
|
43
|
0.344
|
0.0123032904148784
|
TF
|
TF:M03920_1
|
Factor: SP1; motif: RCCMCRCCCMC; match class: 1
|
0.00878435847323308
|
3020
|
125
|
40
|
0.32
|
0.0132450331125828
|
TF
|
TF:M07063_1
|
Factor: Sp1; motif: GGGGCGGGGC; match class: 1
|
0.00878435847323308
|
3495
|
125
|
43
|
0.344
|
0.0123032904148784
|
TF
|
TF:M08205_1
|
Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1
|
0.00878435847323308
|
10438
|
126
|
92
|
0.73015873015873
|
0.00881394903238168
|
TF
|
TF:M03913_1
|
Factor: KLF14; motif: NRCCACGCCCMCYN; match class: 1
|
0.008988417810869
|
64
|
12
|
3
|
0.25
|
0.046875
|
TF
|
TF:M03807_1
|
Factor: SP2; motif: GNNGGGGGCGGGGSN; match class: 1
|
0.00973877563221033
|
4199
|
125
|
48
|
0.384
|
0.0114312931650393
|
TF
|
TF:M10530_1
|
Factor: sp4; motif: NNNGCYCCGCCCCCY; match class: 1
|
0.00973877563221033
|
3780
|
138
|
48
|
0.347826086956522
|
0.0126984126984127
|
TF
|
TF:M07395_1
|
Factor: Sp1; motif: NGGGGCGGGGN; match class: 1
|
0.0109295393011681
|
6334
|
125
|
63
|
0.504
|
0.00994632143984844
|
TF
|
TF:M00932_1
|
Factor: Sp1; motif: NNGGGGCGGGGNN; match class: 1
|
0.0109295393011681
|
6047
|
125
|
61
|
0.488
|
0.0100876467669919
|
TF
|
TF:M00196_1
|
Factor: Sp1; motif: NGGGGGCGGGGYN; match class: 1
|
0.0109295393011681
|
5919
|
125
|
60
|
0.48
|
0.010136847440446
|
TF
|
TF:M03920
|
Factor: SP1; motif: RCCMCRCCCMC
|
0.0118734780452907
|
7283
|
138
|
75
|
0.543478260869565
|
0.0102979541397776
|
TF
|
TF:M00933_1
|
Factor: Sp1; motif: CCCCGCCCCN; match class: 1
|
0.0118734780452907
|
5166
|
139
|
59
|
0.424460431654676
|
0.0114208284939992
|
TF
|
TF:M12173_1
|
Factor: GKLF; motif: NNCCMCRCCCN; match class: 1
|
0.013154512257189
|
4965
|
139
|
57
|
0.410071942446043
|
0.0114803625377644
|
TF
|
TF:M12186_1
|
Factor: BTEB4; motif: NCCACGCCCM; match class: 1
|
0.013154512257189
|
3958
|
130
|
46
|
0.353846153846154
|
0.011622031328954
|
TF
|
TF:M07277_1
|
Factor: BTEB2; motif: RGGGNGKGGN; match class: 1
|
0.013154512257189
|
4149
|
138
|
50
|
0.36231884057971
|
0.0120510966497951
|
TF
|
TF:M03567_1
|
Factor: Sp2; motif: NYSGCCCCGCCCCCY; match class: 1
|
0.013154512257189
|
3614
|
125
|
42
|
0.336
|
0.0116214720531267
|
TF
|
TF:M00716_1
|
Factor: ZF5; motif: GSGCGCGR; match class: 1
|
0.0140740969017658
|
14106
|
137
|
118
|
0.861313868613139
|
0.00836523465192117
|
TF
|
TF:M00803
|
Factor: E2F; motif: GGCGSG
|
0.0140740969017658
|
13190
|
140
|
115
|
0.821428571428571
|
0.00871872630780895
|
TF
|
TF:M09765
|
Factor: SP1; motif: NRGKGGGCGGGGCN
|
0.0177318832133775
|
7469
|
125
|
69
|
0.552
|
0.00923818449591646
|
TF
|
TF:M12156_1
|
Factor: Sp2; motif: NTAAGYCCCGCCCMCTN; match class: 1
|
0.0177318832133775
|
1002
|
125
|
18
|
0.144
|
0.0179640718562874
|
TF
|
TF:M00244_1
|
Factor: NGFI-C; motif: WTGCGTGGGYGG; match class: 1
|
0.0177318832133775
|
1772
|
135
|
27
|
0.2
|
0.0152370203160271
|
TF
|
TF:M00803_1
|
Factor: E2F; motif: GGCGSG; match class: 1
|
0.0177318832133775
|
10230
|
139
|
95
|
0.683453237410072
|
0.00928641251221896
|
TF
|
TF:M10072_1
|
Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR; match class: 1
|
0.0202270952804606
|
6225
|
125
|
60
|
0.48
|
0.00963855421686747
|
TF
|
TF:M10435
|
Factor: Sp2; motif: GGGGCGGGG
|
0.0202270952804606
|
7696
|
140
|
77
|
0.55
|
0.0100051975051975
|
TF
|
TF:M08377_1
|
Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1
|
0.0202270952804606
|
5051
|
129
|
53
|
0.410852713178295
|
0.0104929716887745
|
TF
|
TF:M00931_1
|
Factor: Sp1; motif: GGGGCGGGGC; match class: 1
|
0.0202270952804606
|
5905
|
125
|
58
|
0.464
|
0.00982218458933107
|
TF
|
TF:M07063
|
Factor: Sp1; motif: GGGGCGGGGC
|
0.0202270952804606
|
7696
|
140
|
77
|
0.55
|
0.0100051975051975
|
TF
|
TF:M11531_1
|
Factor: E2F-2; motif: GCGCGCGCGYW; match class: 1
|
0.0202270952804606
|
12351
|
126
|
99
|
0.785714285714286
|
0.00801554529997571
|
TF
|
TF:M11821_1
|
Factor: T3R-beta; motif: NTGACCTNACGTGACCTYA; match class: 1
|
0.02181991967259
|
211
|
134
|
8
|
0.0597014925373134
|
0.037914691943128
|
TF
|
TF:M12186
|
Factor: BTEB4; motif: NCCACGCCCM
|
0.0220543504842967
|
9135
|
125
|
79
|
0.632
|
0.00864805692391899
|
TF
|
TF:M03922
|
Factor: SP4; motif: NWRGCCACGCCCMCTYN
|
0.0250727179978204
|
6046
|
140
|
64
|
0.457142857142857
|
0.0105855110817069
|
TF
|
TF:M09970_1
|
Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN; match class: 1
|
0.0273502466827163
|
3783
|
123
|
41
|
0.333333333333333
|
0.0108379592915675
|
TF
|
TF:M10072
|
Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR
|
0.0286992700939165
|
10494
|
140
|
96
|
0.685714285714286
|
0.00914808461978273
|
TF
|
TF:M04826_1
|
Factor: p300; motif: ACNTCCG; match class: 1
|
0.0289054621481084
|
15260
|
136
|
122
|
0.897058823529412
|
0.00799475753604194
|
TF
|
TF:M12151_1
|
Factor: Sp1; motif: NWRGCCMCGCCCMCN; match class: 1
|
0.0294380488316607
|
2548
|
123
|
31
|
0.252032520325203
|
0.0121664050235479
|
TF
|
TF:M02089_1
|
Factor: E2F-3; motif: GGCGGGN; match class: 1
|
0.0296659652818211
|
9362
|
140
|
88
|
0.628571428571429
|
0.00939970091860714
|
TF
|
TF:M12157_1
|
Factor: KLF15; motif: RCCACGCCCCCC; match class: 1
|
0.0296659652818211
|
816
|
123
|
15
|
0.121951219512195
|
0.0183823529411765
|
TF
|
TF:M03807
|
Factor: SP2; motif: GNNGGGGGCGGGGSN
|
0.0315410597403698
|
8415
|
140
|
81
|
0.578571428571429
|
0.00962566844919786
|
TF
|
TF:M11765
|
Factor: TR2; motif: NRGGTCRYGACCYN
|
0.0315410597403698
|
3058
|
65
|
22
|
0.338461538461538
|
0.00719424460431655
|
TF
|
TF:M11052
|
Factor: Hey2; motif: NNCACGYGNN
|
0.0315410597403698
|
12502
|
139
|
108
|
0.776978417266187
|
0.00863861782114862
|
TF
|
TF:M03582_1
|
Factor: TWIST; motif: CACCTGG; match class: 1
|
0.0315410597403698
|
2579
|
112
|
29
|
0.258928571428571
|
0.0112446684761535
|
TF
|
TF:M00933
|
Factor: Sp1; motif: CCCCGCCCCN
|
0.0327440179360369
|
9715
|
140
|
90
|
0.642857142857143
|
0.00926402470406588
|
TF
|
TF:M05332
|
Factor: Sp2; motif: WGGGCGG
|
0.0327440179360369
|
8578
|
140
|
82
|
0.585714285714286
|
0.00955933784098858
|
TF
|
TF:M05444
|
Factor: CPBP; motif: NGGGCGG
|
0.0327440179360369
|
8578
|
140
|
82
|
0.585714285714286
|
0.00955933784098858
|
TF
|
TF:M05361
|
Factor: Sp6; motif: WGGGCGG
|
0.0327440179360369
|
8578
|
140
|
82
|
0.585714285714286
|
0.00955933784098858
|
TF
|
TF:M01200_1
|
Factor: CTCF; motif: NNNGCCASCAGRKGGCRSNN; match class: 1
|
0.0334804978341912
|
554
|
21
|
5
|
0.238095238095238
|
0.00902527075812274
|
TF
|
TF:M09765_1
|
Factor: SP1; motif: NRGKGGGCGGGGCN; match class: 1
|
0.0345508415935135
|
3318
|
138
|
40
|
0.289855072463768
|
0.0120554550934298
|
TF
|
TF:M04710
|
Factor: CHD2; motif: TCTCGCGAG
|
0.035535506327139
|
14109
|
136
|
115
|
0.845588235294118
|
0.00815082571408321
|
TF
|
TF:M03922_1
|
Factor: SP4; motif: NWRGCCACGCCCMCTYN; match class: 1
|
0.035535506327139
|
2143
|
123
|
27
|
0.219512195121951
|
0.0125991600559963
|
TF
|
TF:M04012
|
Factor: HSFY1; motif: TTTCGAACG
|
0.0360611758175871
|
1013
|
128
|
17
|
0.1328125
|
0.016781836130306
|
TF
|
TF:M04869_1
|
Factor: Egr-1; motif: GCGCATGCG; match class: 1
|
0.0360611758175871
|
10253
|
136
|
91
|
0.669117647058823
|
0.00887545108748659
|
TF
|
TF:M09969
|
Factor: EKLF; motif: NGGGYGKGGCNNGG
|
0.0360611758175871
|
4589
|
123
|
46
|
0.373983739837398
|
0.0100239703639137
|
TF
|
TF:M11603_1
|
Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1
|
0.0360611758175871
|
13184
|
134
|
108
|
0.805970149253731
|
0.00819174757281553
|
TF
|
TF:M00982_1
|
Factor: KROX; motif: CCCGCCCCCRCCCC; match class: 1
|
0.0377947944703973
|
3518
|
132
|
40
|
0.303030303030303
|
0.0113700966458215
|
TF
|
TF:M01259
|
Factor: CTCF; motif: NNNNNNCCASNAGRKGGCRS
|
0.0383372918548717
|
1968
|
75
|
18
|
0.24
|
0.00914634146341463
|
TF
|
TF:M12152_1
|
Factor: Sp1; motif: NWRGCCACGCCCMCN; match class: 1
|
0.0391114569594121
|
2859
|
125
|
33
|
0.264
|
0.0115424973767051
|
TF
|
TF:M01588
|
Factor: GKLF; motif: GCCMCRCCCNNN
|
0.0391114569594121
|
8944
|
123
|
75
|
0.609756097560976
|
0.00838550983899821
|
TF
|
TF:M02071
|
Factor: ETV7; motif: NCCGGAANNN
|
0.0415612180684141
|
10116
|
140
|
92
|
0.657142857142857
|
0.00909450375642546
|
TF
|
TF:M09970
|
Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN
|
0.0423025425842266
|
7728
|
125
|
68
|
0.544
|
0.0087991718426501
|
TF
|
TF:M12156
|
Factor: Sp2; motif: NTAAGYCCCGCCCMCTN
|
0.0423611043572132
|
4320
|
128
|
45
|
0.3515625
|
0.0104166666666667
|
TF
|
TF:M09723_1
|
Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS; match class: 1
|
0.0423786823797751
|
6113
|
125
|
57
|
0.456
|
0.0093243906428922
|
TF
|
TF:M07615
|
Factor: Sp3; motif: GGGGCGGGGSNN
|
0.0423786823797751
|
6807
|
140
|
68
|
0.485714285714286
|
0.00998971646834141
|
TF
|
TF:M09748
|
Factor: RAD21; motif: NCCASYAGRKGGCRSNN
|
0.0423851597186875
|
2016
|
75
|
18
|
0.24
|
0.00892857142857143
|
TF
|
TF:M11531
|
Factor: E2F-2; motif: GCGCGCGCGYW
|
0.0423851597186875
|
13270
|
126
|
102
|
0.80952380952381
|
0.00768651092690279
|
TF
|
TF:M12147_1
|
Factor: SP8; motif: RNCACGCCCMCN; match class: 1
|
0.0423851597186875
|
331
|
22
|
4
|
0.181818181818182
|
0.0120845921450151
|
TF
|
TF:M00333_1
|
Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1
|
0.0423851597186875
|
12401
|
140
|
107
|
0.764285714285714
|
0.0086283364244819
|
TF
|
TF:M01873_1
|
Factor: Egr-1; motif: GCGGGGGCGG; match class: 1
|
0.0423851597186875
|
2672
|
124
|
31
|
0.25
|
0.0116017964071856
|
TF
|
TF:M11434
|
Factor: Elk-1; motif: NRSCGGAAGNN
|
0.0423851597186875
|
8219
|
129
|
73
|
0.565891472868217
|
0.00888185910694732
|
TF
|
TF:M03914_1
|
Factor: KLF16; motif: GMCACGCCCCC; match class: 1
|
0.0458204889556757
|
710
|
123
|
13
|
0.105691056910569
|
0.0183098591549296
|
TF
|
TF:M12153
|
Factor: Sp3; motif: NGCCACGCCCMCN
|
0.045991636798741
|
6205
|
132
|
60
|
0.454545454545455
|
0.0096696212731668
|
WP
|
WP:WP4396
|
Nonalcoholic fatty liver disease
|
8.84794425917076e-07
|
159
|
93
|
14
|
0.150537634408602
|
0.0880503144654088
|
WP
|
WP:WP111
|
Electron Transport Chain (OXPHOS system in mitochondria)
|
3.63649460313045e-05
|
105
|
93
|
10
|
0.10752688172043
|
0.0952380952380952
|
WP
|
WP:WP4324
|
Mitochondrial complex I assembly model OXPHOS system
|
0.00021930618348669
|
56
|
93
|
7
|
0.0752688172043011
|
0.125
|
WP
|
WP:WP623
|
Oxidative phosphorylation
|
0.000328559753723149
|
62
|
93
|
7
|
0.0752688172043011
|
0.112903225806452
|