pMA06 program activity among Mast cells

Activation of pMA06
pMA06 gene program activation in Mast cells.
Gene program activation of pMA06 by different cell subtypes
pMA06 gene program activation among cells of different subtypes (Mast cells).

pMA06 top program genes

Top genes of pMA06 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pMA06 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pMA06
pMA06 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0006518 peptide metabolic process 0.00255625779955862 955 103 19 0.184466019417476 0.0198952879581152
GO:BP GO:0043603 cellular amide metabolic process 0.00255625779955862 1241 103 22 0.213592233009709 0.0177276390008058
GO:BP GO:0048523 negative regulation of cellular process 0.00718411630624657 5139 47 28 0.595744680851064 0.00544853084257638
GO:BP GO:0051248 negative regulation of protein metabolic process 0.00718411630624657 1151 114 21 0.184210526315789 0.0182450043440487
GO:BP GO:0006446 regulation of translational initiation 0.0112654938202555 80 134 6 0.0447761194029851 0.075
GO:BP GO:0046456 icosanoid biosynthetic process 0.0112654938202555 56 19 3 0.157894736842105 0.0535714285714286
GO:BP GO:0048519 negative regulation of biological process 0.0112654938202555 5757 47 29 0.617021276595745 0.00503734583984714
GO:BP GO:0051246 regulation of protein metabolic process 0.0112654938202555 2704 115 35 0.304347826086957 0.0129437869822485
GO:BP GO:0002183 cytoplasmic translational initiation 0.012188574650236 35 96 4 0.0416666666666667 0.114285714285714
GO:BP GO:0034248 regulation of cellular amide metabolic process 0.0147748589430726 535 103 12 0.116504854368932 0.0224299065420561
GO:BP GO:0031329 regulation of cellular catabolic process 0.0147748589430726 866 46 10 0.217391304347826 0.0115473441108545
GO:BP GO:0045727 positive regulation of translation 0.0147748589430726 140 54 5 0.0925925925925926 0.0357142857142857
GO:BP GO:0016485 protein processing 0.0147748589430726 235 103 8 0.0776699029126214 0.0340425531914894
GO:BP GO:0006950 response to stress 0.0149186276067442 4170 38 20 0.526315789473684 0.00479616306954436
GO:BP GO:0006465 signal peptide processing 0.0149186276067442 11 139 3 0.0215827338129496 0.272727272727273
GO:BP GO:0006413 translational initiation 0.0201731792353717 201 134 8 0.0597014925373134 0.0398009950248756
GO:BP GO:0034250 positive regulation of cellular amide metabolic process 0.021954026833828 171 54 5 0.0925925925925926 0.0292397660818713
GO:BP GO:0009892 negative regulation of metabolic process 0.021954026833828 3479 43 19 0.441860465116279 0.00546133946536361
GO:BP GO:1901698 response to nitrogen compound 0.0224416220483446 1172 40 10 0.25 0.00853242320819113
GO:BP GO:1905517 macrophage migration 0.0224416220483446 56 101 4 0.0396039603960396 0.0714285714285714
GO:BP GO:0009894 regulation of catabolic process 0.0224416220483446 1033 46 10 0.217391304347826 0.00968054211035818
GO:BP GO:0045861 negative regulation of proteolysis 0.0224416220483446 359 103 9 0.087378640776699 0.0250696378830084
GO:BP GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 0.0224416220483446 55 40 3 0.075 0.0545454545454545
GO:BP GO:0031324 negative regulation of cellular metabolic process 0.0224416220483446 2719 55 19 0.345454545454545 0.00698786318499448
GO:BP GO:0010561 negative regulation of glycoprotein biosynthetic process 0.0224416220483446 25 92 3 0.0326086956521739 0.12
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0224416220483446 2541 115 31 0.269565217391304 0.0121999212908304
GO:BP GO:0002181 cytoplasmic translation 0.0224416220483446 103 96 5 0.0520833333333333 0.0485436893203883
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 0.0224416220483446 3241 43 18 0.418604651162791 0.00555384140697316
GO:BP GO:0065008 regulation of biological quality 0.0224416220483446 4131 53 24 0.452830188679245 0.00580973129992738
GO:BP GO:0043086 negative regulation of catalytic activity 0.0224416220483446 851 114 15 0.131578947368421 0.0176263219741481
GO:BP GO:0001975 response to amphetamine 0.0224416220483446 31 75 3 0.04 0.0967741935483871
GO:BP GO:0006690 icosanoid metabolic process 0.0224416220483446 124 19 3 0.157894736842105 0.0241935483870968
GO:BP GO:0006508 proteolysis 0.0224416220483446 1836 67 17 0.253731343283582 0.00925925925925926
GO:BP GO:0006417 regulation of translation 0.0224416220483446 462 63 8 0.126984126984127 0.0173160173160173
GO:BP GO:1901685 glutathione derivative metabolic process 0.0225367485160106 21 117 3 0.0256410256410256 0.142857142857143
GO:BP GO:1901687 glutathione derivative biosynthetic process 0.0225367485160106 21 117 3 0.0256410256410256 0.142857142857143
GO:BP GO:0009056 catabolic process 0.0225367485160106 2744 69 22 0.318840579710145 0.00801749271137026
GO:BP GO:0008277 regulation of G protein-coupled receptor signaling pathway 0.0225367485160106 149 40 4 0.1 0.0268456375838926
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 0.0225367485160106 2518 55 18 0.327272727272727 0.00714853057982526
GO:BP GO:0051604 protein maturation 0.0225367485160106 306 103 8 0.0776699029126214 0.0261437908496732
GO:BP GO:0044092 negative regulation of molecular function 0.0225367485160106 1219 119 19 0.159663865546218 0.0155865463494668
GO:BP GO:1903019 negative regulation of glycoprotein metabolic process 0.0226241962115879 28 92 3 0.0326086956521739 0.107142857142857
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 0.0226241962115879 2255 67 19 0.283582089552239 0.00842572062084257
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.0246525282146112 1082 114 17 0.149122807017544 0.0157116451016636
GO:BP GO:0044248 cellular catabolic process 0.0258300667028361 2347 46 15 0.326086956521739 0.0063911376224968
GO:BP GO:0042773 ATP synthesis coupled electron transport 0.0265718005940161 100 121 5 0.0413223140495868 0.05
GO:BP GO:0050896 response to stimulus 0.0265718005940161 9407 41 32 0.780487804878049 0.00340172212182417
GO:BP GO:0009607 response to biotic stimulus 0.0265718005940161 1626 79 17 0.215189873417722 0.0104551045510455
GO:BP GO:0010243 response to organonitrogen compound 0.0265718005940161 1085 40 9 0.225 0.00829493087557604
GO:BP GO:0042775 mitochondrial ATP synthesis coupled electron transport 0.0265718005940161 99 121 5 0.0413223140495868 0.0505050505050505
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0277311288409888 253 103 7 0.0679611650485437 0.0276679841897233
GO:BP GO:0009628 response to abiotic stimulus 0.028091844887349 1261 36 9 0.25 0.00713719270420301
GO:BP GO:0010033 response to organic substance 0.028091844887349 3412 34 15 0.441176470588235 0.00439624853458382
GO:BP GO:1901564 organonitrogen compound metabolic process 0.0281283098173333 6792 47 29 0.617021276595745 0.00426972909305065
GO:BP GO:0010955 negative regulation of protein processing 0.0286899009180496 31 103 3 0.029126213592233 0.0967741935483871
GO:BP GO:1903318 negative regulation of protein maturation 0.0286899009180496 31 103 3 0.029126213592233 0.0967741935483871
GO:BP GO:0006631 fatty acid metabolic process 0.0286899009180496 404 19 4 0.210526315789474 0.0099009900990099
GO:BP GO:0043604 amide biosynthetic process 0.0286899009180496 932 102 14 0.137254901960784 0.0150214592274678
GO:BP GO:0016241 regulation of macroautophagy 0.0287014409005166 161 46 4 0.0869565217391304 0.0248447204968944
GO:BP GO:0007035 vacuolar acidification 0.0300190696378829 24 139 3 0.0215827338129496 0.125
GO:BP GO:0010466 negative regulation of peptidase activity 0.030417340879308 267 103 7 0.0679611650485437 0.0262172284644195
GO:BP GO:0051452 intracellular pH reduction 0.0322659989566558 56 139 4 0.0287769784172662 0.0714285714285714
GO:BP GO:0014075 response to amine 0.0324633567270076 46 75 3 0.04 0.0652173913043478
GO:BP GO:0043207 response to external biotic stimulus 0.0359657304861472 1594 79 16 0.20253164556962 0.0100376411543287
GO:BP GO:0043488 regulation of mRNA stability 0.0359657304861472 191 20 3 0.15 0.0157068062827225
GO:BP GO:0051707 response to other organism 0.0359657304861472 1592 79 16 0.20253164556962 0.0100502512562814
GO:BP GO:0045851 pH reduction 0.0359657304861472 59 139 4 0.0287769784172662 0.0677966101694915
GO:BP GO:0010506 regulation of autophagy 0.0359657304861472 336 65 6 0.0923076923076923 0.0178571428571429
GO:BP GO:0006412 translation 0.0359657304861472 764 102 12 0.117647058823529 0.0157068062827225
GO:BP GO:0031323 regulation of cellular metabolic process 0.0359657304861472 6269 65 35 0.538461538461538 0.00558302759610783
GO:BP GO:0022904 respiratory electron transport chain 0.0359657304861472 117 121 5 0.0413223140495868 0.0427350427350427
GO:BP GO:0019222 regulation of metabolic process 0.0359657304861472 7148 48 30 0.625 0.00419697817571349
GO:BP GO:0016236 macroautophagy 0.0359657304861472 312 46 5 0.108695652173913 0.016025641025641
GO:BP GO:0015837 amine transport 0.0360106345126339 99 40 3 0.075 0.0303030303030303
GO:BP GO:0022900 electron transport chain 0.0360106345126339 180 121 6 0.0495867768595041 0.0333333333333333
GO:BP GO:0043487 regulation of RNA stability 0.0360106345126339 201 20 3 0.15 0.0149253731343284
GO:BP GO:1901700 response to oxygen-containing compound 0.0360106345126339 1739 60 14 0.233333333333333 0.00805060379528465
GO:BP GO:1901566 organonitrogen compound biosynthetic process 0.0360106345126339 1853 102 21 0.205882352941176 0.011332973556395
GO:BP GO:0009617 response to bacterium 0.0362734091919526 743 79 10 0.126582278481013 0.0134589502018843
GO:BP GO:0032940 secretion by cell 0.0362734091919526 1364 110 18 0.163636363636364 0.0131964809384164
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0362734091919526 470 103 9 0.087378640776699 0.0191489361702128
GO:BP GO:0006812 cation transport 0.037259570963687 1197 59 11 0.186440677966102 0.00918964076858814
GO:BP GO:0061013 regulation of mRNA catabolic process 0.0391781902663978 213 20 3 0.15 0.0140845070422535
GO:BP GO:0043043 peptide biosynthetic process 0.0391781902663978 790 102 12 0.117647058823529 0.0151898734177215
GO:BP GO:1902600 proton transmembrane transport 0.0393737005758856 157 59 4 0.0677966101694915 0.0254777070063694
GO:BP GO:1903792 negative regulation of anion transport 0.0393737005758856 235 67 5 0.0746268656716418 0.0212765957446809
GO:BP GO:0065003 protein-containing complex assembly 0.0393737005758856 1680 114 21 0.184210526315789 0.0125
GO:BP GO:1905521 regulation of macrophage migration 0.0393737005758856 42 101 3 0.0297029702970297 0.0714285714285714
GO:BP GO:0043271 negative regulation of ion transport 0.0393737005758856 349 45 5 0.111111111111111 0.0143266475644699
GO:BP GO:0009890 negative regulation of biosynthetic process 0.0393737005758856 1740 43 11 0.255813953488372 0.00632183908045977
GO:BP GO:0010035 response to inorganic substance 0.0393737005758856 575 41 6 0.146341463414634 0.0104347826086957
GO:BP GO:0042221 response to chemical 0.0393737005758856 4781 41 20 0.48780487804878 0.00418322526668061
GO:BP GO:0043933 protein-containing complex subunit organization 0.0393737005758856 1963 79 18 0.227848101265823 0.00916963830871116
GO:BP GO:0048640 negative regulation of developmental growth 0.0393737005758856 112 40 3 0.075 0.0267857142857143
GO:BP GO:1901652 response to peptide 0.0395879106206344 551 59 7 0.11864406779661 0.0127041742286751
GO:BP GO:0050900 leukocyte migration 0.0404986634494805 511 48 6 0.125 0.0117416829745597
GO:BP GO:0050790 regulation of catalytic activity 0.0404986634494805 2545 115 28 0.243478260869565 0.0110019646365422
GO:BP GO:0046006 regulation of activated T cell proliferation 0.0404986634494805 45 103 3 0.029126213592233 0.0666666666666667
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.0404986634494805 1477 30 8 0.266666666666667 0.00541638456330399
GO:BP GO:0140352 export from cell 0.0404986634494805 1418 110 18 0.163636363636364 0.0126939351198872
GO:BP GO:0042982 amyloid precursor protein metabolic process 0.0404986634494805 96 103 4 0.0388349514563107 0.0416666666666667
GO:BP GO:0019538 protein metabolic process 0.0404986634494805 5808 47 25 0.531914893617021 0.00430440771349862
GO:BP GO:0055088 lipid homeostasis 0.0413497570718509 167 60 4 0.0666666666666667 0.0239520958083832
GO:BP GO:0042542 response to hydrogen peroxide 0.0413497570718509 150 32 3 0.09375 0.02
GO:BP GO:0016032 viral process 0.0413497570718509 942 67 10 0.149253731343284 0.0106157112526539
GO:BP GO:0009636 response to toxic substance 0.0413497570718509 243 69 5 0.072463768115942 0.0205761316872428
GO:BP GO:0019731 antibacterial humoral response 0.0413497570718509 62 77 3 0.038961038961039 0.0483870967741935
GO:BP GO:0006914 autophagy 0.0414266748278875 543 46 6 0.130434782608696 0.0110497237569061
GO:BP GO:0080134 regulation of response to stress 0.0414266748278875 1443 31 8 0.258064516129032 0.00554400554400554
GO:BP GO:0061919 process utilizing autophagic mechanism 0.0414266748278875 543 46 6 0.130434782608696 0.0110497237569061
GO:BP GO:0009057 macromolecule catabolic process 0.0420823605636512 1468 67 13 0.194029850746269 0.00885558583106267
GO:BP GO:0051336 regulation of hydrolase activity 0.0420823605636512 1321 110 17 0.154545454545455 0.0128690386071158
GO:BP GO:0006955 immune response 0.0435031017362894 2311 65 17 0.261538461538462 0.00735612289052358
GO:BP GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 0.0439258199650687 77 65 3 0.0461538461538462 0.038961038961039
GO:BP GO:0050798 activated T cell proliferation 0.0443150372953538 49 103 3 0.029126213592233 0.0612244897959184
GO:BP GO:0010559 regulation of glycoprotein biosynthetic process 0.0445180031636878 55 92 3 0.0326086956521739 0.0545454545454545
GO:BP GO:0061024 membrane organization 0.0446747163525484 973 56 9 0.160714285714286 0.0092497430626927
GO:BP GO:1903311 regulation of mRNA metabolic process 0.0458596530606716 356 31 4 0.129032258064516 0.0112359550561798
GO:BP GO:0042063 gliogenesis 0.0458596530606716 308 36 4 0.111111111111111 0.012987012987013
GO:BP GO:1901361 organic cyclic compound catabolic process 0.0458596530606716 651 54 7 0.12962962962963 0.010752688172043
GO:BP GO:0051247 positive regulation of protein metabolic process 0.0458596530606716 1564 30 8 0.266666666666667 0.0051150895140665
GO:BP GO:0010608 posttranscriptional regulation of gene expression 0.0458596530606716 896 40 7 0.175 0.0078125
GO:BP GO:0044265 cellular macromolecule catabolic process 0.0458596530606716 1231 54 10 0.185185185185185 0.00812347684809098
GO:BP GO:0009719 response to endogenous stimulus 0.0458596530606716 1683 34 9 0.264705882352941 0.0053475935828877
GO:BP GO:0006887 exocytosis 0.0470017265974964 904 110 13 0.118181818181818 0.0143805309734513
GO:BP GO:0030162 regulation of proteolysis 0.0477522157917264 752 74 9 0.121621621621622 0.011968085106383
GO:BP GO:0006119 oxidative phosphorylation 0.0477522157917264 151 121 5 0.0413223140495868 0.033112582781457
GO:BP GO:0052548 regulation of endopeptidase activity 0.0478198490124187 437 103 8 0.0776699029126214 0.0183066361556064
GO:BP GO:0070972 protein localization to endoplasmic reticulum 0.0482124409067983 146 38 3 0.0789473684210526 0.0205479452054795
GO:BP GO:0044403 biological process involved in symbiotic interaction 0.0485394862661136 1001 67 10 0.149253731343284 0.00999000999000999
GO:BP GO:0034763 negative regulation of transmembrane transport 0.0493354522288341 132 45 3 0.0666666666666667 0.0227272727272727
GO:BP GO:0034766 negative regulation of ion transmembrane transport 0.0493354522288341 131 45 3 0.0666666666666667 0.0229007633587786
GO:BP GO:1901575 organic substance catabolic process 0.0493354522288341 2267 69 17 0.246376811594203 0.00749889722099691
GO:BP GO:0051716 cellular response to stimulus 0.0493354522288341 7781 38 25 0.657894736842105 0.00321295463308058
GO:BP GO:0042129 regulation of T cell proliferation 0.0493354522288341 176 110 5 0.0454545454545455 0.0284090909090909
GO:BP GO:0046903 secretion 0.0493354522288341 1501 110 18 0.163636363636364 0.0119920053297801
GO:BP GO:1903018 regulation of glycoprotein metabolic process 0.0493354522288341 62 92 3 0.0326086956521739 0.0483870967741935
GO:BP GO:0070887 cellular response to chemical stimulus 0.0493354522288341 3393 36 14 0.388888888888889 0.00412614205717654
GO:BP GO:0042632 cholesterol homeostasis 0.0493354522288341 99 60 3 0.05 0.0303030303030303
GO:BP GO:0006402 mRNA catabolic process 0.0493354522288341 384 31 4 0.129032258064516 0.0104166666666667
GO:BP GO:0006810 transport 0.0493354522288341 5224 56 26 0.464285714285714 0.00497702909647779
GO:BP GO:0009605 response to external stimulus 0.0493354522288341 2944 67 20 0.298507462686567 0.00679347826086957
GO:BP GO:0010508 positive regulation of autophagy 0.0493354522288341 124 46 3 0.0652173913043478 0.0241935483870968
GO:BP GO:0010558 negative regulation of macromolecule biosynthetic process 0.0493354522288341 1639 43 10 0.232558139534884 0.0061012812690665
GO:BP GO:0010629 negative regulation of gene expression 0.0493354522288341 1460 55 11 0.2 0.00753424657534247
GO:BP GO:0032787 monocarboxylic acid metabolic process 0.0493354522288341 658 19 4 0.210526315789474 0.0060790273556231
GO:BP GO:0022618 ribonucleoprotein complex assembly 0.0493354522288341 197 140 6 0.0428571428571429 0.0304568527918782
GO:BP GO:0055092 sterol homeostasis 0.0495551839156798 100 60 3 0.05 0.03
GO:CC GO:0031410 cytoplasmic vesicle 0.000466593903102615 2424 84 27 0.321428571428571 0.0111386138613861
GO:CC GO:0005737 cytoplasm 0.000466593903102615 11911 79 68 0.860759493670886 0.00570900847955671
GO:CC GO:0031982 vesicle 0.000466593903102615 4055 127 51 0.401574803149606 0.012577065351418
GO:CC GO:0097708 intracellular vesicle 0.000466593903102615 2428 84 27 0.321428571428571 0.0111202635914333
GO:CC GO:0070062 extracellular exosome 0.000895704203336597 2176 143 35 0.244755244755245 0.0160845588235294
GO:CC GO:0043230 extracellular organelle 0.000910357547355856 2263 143 35 0.244755244755245 0.0154661953159523
GO:CC GO:0016282 eukaryotic 43S preinitiation complex 0.000910357547355856 17 64 3 0.046875 0.176470588235294
GO:CC GO:0043227 membrane-bounded organelle 0.000910357547355856 12858 131 110 0.83969465648855 0.00855498522320734
GO:CC GO:1903561 extracellular vesicle 0.000910357547355856 2261 143 35 0.244755244755245 0.0154798761609907
GO:CC GO:0012505 endomembrane system 0.000910357547355856 4640 106 46 0.433962264150943 0.00991379310344828
GO:CC GO:0070993 translation preinitiation complex 0.00100596651736006 18 64 3 0.046875 0.166666666666667
GO:CC GO:0031090 organelle membrane 0.00204049673739622 3612 59 24 0.406779661016949 0.00664451827242525
GO:CC GO:0005773 vacuole 0.00263064820431526 810 57 10 0.175438596491228 0.0123456790123457
GO:CC GO:0030662 coated vesicle membrane 0.00303358628383011 177 56 5 0.0892857142857143 0.0282485875706215
GO:CC GO:0005764 lysosome 0.00303358628383011 712 106 13 0.122641509433962 0.0182584269662921
GO:CC GO:0000323 lytic vacuole 0.00303358628383011 712 106 13 0.122641509433962 0.0182584269662921
GO:CC GO:0030665 clathrin-coated vesicle membrane 0.0035652994229152 114 51 4 0.0784313725490196 0.0350877192982456
GO:CC GO:0005925 focal adhesion 0.0035652994229152 420 26 5 0.192307692307692 0.0119047619047619
GO:CC GO:0030055 cell-substrate junction 0.0035652994229152 427 26 5 0.192307692307692 0.0117096018735363
GO:CC GO:0098803 respiratory chain complex 0.0035652994229152 86 121 5 0.0413223140495868 0.0581395348837209
GO:CC GO:0098588 bounding membrane of organelle 0.0035652994229152 2158 76 20 0.263157894736842 0.0092678405931418
GO:CC GO:0005746 mitochondrial respirasome 0.00361939452500495 89 121 5 0.0413223140495868 0.0561797752808989
GO:CC GO:0010008 endosome membrane 0.00524336973101723 505 67 8 0.119402985074627 0.0158415841584158
GO:CC GO:0070469 respirasome 0.00651860312467758 103 121 5 0.0413223140495868 0.0485436893203883
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.00684938350344257 779 110 13 0.118181818181818 0.0166880616174583
GO:CC GO:0030136 clathrin-coated vesicle 0.00684938350344257 193 67 5 0.0746268656716418 0.0259067357512953
GO:CC GO:0030135 coated vesicle 0.00684938350344257 295 67 6 0.0895522388059701 0.0203389830508475
GO:CC GO:0005829 cytosol 0.00684938350344257 5303 142 58 0.408450704225352 0.0109372053554592
GO:CC GO:0005794 Golgi apparatus 0.00684938350344257 1623 106 20 0.188679245283019 0.0123228589032656
GO:CC GO:0012506 vesicle membrane 0.00798989704874739 800 110 13 0.118181818181818 0.01625
GO:CC GO:1990204 oxidoreductase complex 0.00826783153310933 113 121 5 0.0413223140495868 0.0442477876106195
GO:CC GO:0099503 secretory vesicle 0.00826783153310933 1020 110 15 0.136363636363636 0.0147058823529412
GO:CC GO:0032991 protein-containing complex 0.0102668419417939 5548 34 19 0.558823529411765 0.00342465753424658
GO:CC GO:0030141 secretory granule 0.0120267151332016 851 110 13 0.118181818181818 0.0152761457109283
GO:CC GO:0005622 intracellular anatomical structure 0.0143992691016048 14790 79 72 0.911392405063291 0.00486815415821501
GO:CC GO:0005615 extracellular space 0.014829768659973 3594 127 38 0.299212598425197 0.0105731775180857
GO:CC GO:0016324 apical plasma membrane 0.0177856491987781 361 30 4 0.133333333333333 0.0110803324099723
GO:CC GO:0098800 inner mitochondrial membrane protein complex 0.0179547868874315 146 121 5 0.0413223140495868 0.0342465753424658
GO:CC GO:0043226 organelle 0.0188086935390838 14008 79 69 0.873417721518987 0.00492575671045117
GO:CC GO:0031301 integral component of organelle membrane 0.0188086935390838 382 70 6 0.0857142857142857 0.0157068062827225
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 0.0214441245262894 158 36 3 0.0833333333333333 0.0189873417721519
GO:CC GO:0031300 intrinsic component of organelle membrane 0.0239510219669342 413 141 9 0.0638297872340425 0.0217917675544794
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 0.0239510219669342 166 36 3 0.0833333333333333 0.0180722891566265
GO:CC GO:0005768 endosome 0.0254480660694366 987 84 11 0.130952380952381 0.011144883485309
GO:CC GO:1902494 catalytic complex 0.0259443799141244 1441 121 18 0.148760330578512 0.0124913254684247
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.0259443799141244 11296 47 37 0.787234042553192 0.00327549575070822
GO:CC GO:0045177 apical part of cell 0.0259443799141244 431 30 4 0.133333333333333 0.00928074245939675
GO:CC GO:0070161 anchoring junction 0.0276431382937372 836 26 5 0.192307692307692 0.00598086124401914
GO:CC GO:0031461 cullin-RING ubiquitin ligase complex 0.0305021816417397 166 81 4 0.0493827160493827 0.0240963855421687
GO:CC GO:0030667 secretory granule membrane 0.031848179820718 303 135 7 0.0518518518518519 0.0231023102310231
GO:CC GO:1990904 ribonucleoprotein complex 0.0364685802873349 688 94 9 0.0957446808510638 0.0130813953488372
GO:CC GO:0030658 transport vesicle membrane 0.0369030547996949 209 70 4 0.0571428571428571 0.0191387559808612
GO:CC GO:0044306 neuron projection terminus 0.0373752337019463 144 103 4 0.0388349514563107 0.0277777777777778
GO:CC GO:0030672 synaptic vesicle membrane 0.0373752337019463 111 70 3 0.0428571428571429 0.027027027027027
GO:CC GO:0062023 collagen-containing extracellular matrix 0.0373752337019463 421 19 3 0.157894736842105 0.00712589073634204
GO:CC GO:0099501 exocytic vesicle membrane 0.0373752337019463 111 70 3 0.0428571428571429 0.027027027027027
GO:CC GO:0031902 late endosome membrane 0.0382831025789269 140 57 3 0.0526315789473684 0.0214285714285714
GO:CC GO:0031967 organelle envelope 0.0388875602101165 1237 46 8 0.173913043478261 0.00646725949878739
GO:CC GO:0031975 envelope 0.0388875602101165 1237 46 8 0.173913043478261 0.00646725949878739
GO:CC GO:0098552 side of membrane 0.0395531316539591 619 40 5 0.125 0.00807754442649435
GO:CC GO:0030139 endocytic vesicle 0.0412921427201689 306 28 3 0.107142857142857 0.00980392156862745
GO:CC GO:0005774 vacuolar membrane 0.0418103747058064 441 57 5 0.087719298245614 0.0113378684807256
GO:CC GO:0043202 lysosomal lumen 0.0424640151395534 97 90 3 0.0333333333333333 0.0309278350515464
GO:CC GO:0016607 nuclear speck 0.0436114068940593 412 140 8 0.0571428571428571 0.0194174757281553
GO:CC GO:0005740 mitochondrial envelope 0.0436114068940593 797 59 7 0.11864406779661 0.00878293601003764
GO:CC GO:0098793 presynapse 0.0457805951396473 521 135 9 0.0666666666666667 0.017274472168906
GO:CC GO:0045335 phagocytic vesicle 0.0465033595174651 137 67 3 0.0447761194029851 0.0218978102189781
GO:MF GO:0045182 translation regulator activity 0.00372976982162137 155 64 6 0.09375 0.0387096774193548
GO:MF GO:0003743 translation initiation factor activity 0.00372976982162137 58 96 5 0.0520833333333333 0.0862068965517241
GO:MF GO:0019865 immunoglobulin binding 0.00576584099258122 23 52 3 0.0576923076923077 0.130434782608696
GO:MF GO:0001540 amyloid-beta binding 0.0095330844293649 83 103 5 0.0485436893203883 0.0602409638554217
GO:MF GO:0001965 G-protein alpha-subunit binding 0.00990873303163454 27 75 3 0.04 0.111111111111111
GO:MF GO:0044877 protein-containing complex binding 0.00990873303163454 1287 31 9 0.290322580645161 0.00699300699300699
GO:MF GO:0008135 translation factor activity, RNA binding 0.00990873303163454 99 96 5 0.0520833333333333 0.0505050505050505
GO:MF GO:0003723 RNA binding 0.0101243170779919 1943 140 29 0.207142857142857 0.0149253731343284
GO:MF GO:0005521 lamin binding 0.0101243170779919 17 133 3 0.0225563909774436 0.176470588235294
GO:MF GO:0090079 translation regulator activity, nucleic acid binding 0.0107133016756248 123 134 6 0.0447761194029851 0.0487804878048781
GO:MF GO:0004857 enzyme inhibitor activity 0.0107133016756248 385 103 9 0.087378640776699 0.0233766233766234
GO:MF GO:0005515 protein binding 0.0221571308038271 14767 111 101 0.90990990990991 0.00683957472743279
GO:MF GO:0009055 electron transfer activity 0.0266604676333683 148 59 4 0.0677966101694915 0.027027027027027
GO:MF GO:0004386 helicase activity 0.0266604676333683 162 86 5 0.0581395348837209 0.0308641975308642
GO:MF GO:0043021 ribonucleoprotein complex binding 0.0266604676333683 137 63 4 0.0634920634920635 0.0291970802919708
GO:MF GO:0016790 thiolester hydrolase activity 0.0266604676333683 43 91 3 0.032967032967033 0.0697674418604651
GO:MF GO:0003724 RNA helicase activity 0.0281465214436631 76 61 3 0.0491803278688525 0.0394736842105263
GO:MF GO:0048306 calcium-dependent protein binding 0.0281465214436631 82 51 3 0.0588235294117647 0.0365853658536585
GO:MF GO:0005516 calmodulin binding 0.0281465214436631 204 51 4 0.0784313725490196 0.0196078431372549
GO:MF GO:0019899 enzyme binding 0.0281465214436631 2074 38 11 0.289473684210526 0.00530376084860174
GO:MF GO:0017111 nucleoside-triphosphatase activity 0.0281465214436631 872 40 7 0.175 0.00802752293577982
GO:MF GO:0003697 single-stranded DNA binding 0.0318241197043994 119 48 3 0.0625 0.0252100840336134
GO:MF GO:0004866 endopeptidase inhibitor activity 0.0318241197043994 176 103 5 0.0485436893203883 0.0284090909090909
GO:MF GO:0033218 amide binding 0.0318241197043994 389 120 8 0.0666666666666667 0.0205655526992288
GO:MF GO:0061135 endopeptidase regulator activity 0.0318241197043994 188 103 5 0.0485436893203883 0.0265957446808511
GO:MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0318241197043994 930 40 7 0.175 0.00752688172043011
GO:MF GO:0016817 hydrolase activity, acting on acid anhydrides 0.0318241197043994 930 40 7 0.175 0.00752688172043011
GO:MF GO:0031625 ubiquitin protein ligase binding 0.0318241197043994 296 38 4 0.105263157894737 0.0135135135135135
GO:MF GO:0030414 peptidase inhibitor activity 0.0318241197043994 182 103 5 0.0485436893203883 0.0274725274725275
GO:MF GO:0016462 pyrophosphatase activity 0.0318241197043994 928 40 7 0.175 0.00754310344827586
GO:MF GO:0047485 protein N-terminus binding 0.0318241197043994 111 54 3 0.0555555555555556 0.027027027027027
GO:MF GO:0044389 ubiquitin-like protein ligase binding 0.0318241197043994 314 38 4 0.105263157894737 0.0127388535031847
GO:MF GO:0030234 enzyme regulator activity 0.0318241197043994 1248 115 16 0.139130434782609 0.0128205128205128
GO:MF GO:0042277 peptide binding 0.0318601828281598 314 120 7 0.0583333333333333 0.0222929936305732
GO:MF GO:0016787 hydrolase activity 0.0333285533340778 2615 6 4 0.666666666666667 0.00152963671128107
GO:MF GO:0045296 cadherin binding 0.0463356861646096 333 125 7 0.056 0.021021021021021
GO:MF GO:0042803 protein homodimerization activity 0.0471051573612859 676 48 6 0.125 0.00887573964497041
GO:MF GO:0061134 peptidase regulator activity 0.0471633154940534 224 103 5 0.0485436893203883 0.0223214285714286
TF TF:M10727_1 Factor: HOXB8; motif: RTCRTTAN; match class: 1 0.00840311325513785 1379 139 26 0.18705035971223 0.018854242204496
TF TF:M01489 Factor: NKX6A; motif: NNNAATTAATTAMYNNG 0.00840311325513785 971 130 21 0.161538461538462 0.0216271884654995
TF TF:M08894 Factor: OVOL; motif: ANRTAACGG 0.00840311325513785 8109 112 70 0.625 0.00863238377111851
TF TF:M10948_1 Factor: rax; motif: NNCRTTAN; match class: 1 0.0123596829807859 5245 106 49 0.462264150943396 0.00934223069590086
TF TF:M07286 Factor: FOXO1A; motif: TTGTTTWN 0.0123596829807859 4891 115 49 0.426086956521739 0.0100184011449601
TF TF:M04556 Factor: SRY; motif: AACAATNNNCATTGTT 0.0123596829807859 7857 123 72 0.585365853658537 0.00916380297823597
TF TF:M00347_1 Factor: GATA-1; motif: MNAGATAANR; match class: 1 0.0123596829807859 772 23 7 0.304347826086957 0.00906735751295337
TF TF:M00260 Factor: HLF; motif: GTTACRYAAT 0.0123596829807859 2816 136 39 0.286764705882353 0.0138494318181818
TF TF:M01420_1 Factor: Ncx; motif: NAATNAATTAATAANWW; match class: 1 0.0123596829807859 2151 111 28 0.252252252252252 0.0130172013017201
TF TF:M01452_1 Factor: HOXA5; motif: ANGNTAATTANCNNAN; match class: 1 0.0123596829807859 1429 135 25 0.185185185185185 0.0174947515745276
TF TF:M12070 Factor: CIZ; motif: TTTTNNNNNNNNNNNNNAAAAA 0.0123596829807859 2624 112 32 0.285714285714286 0.0121951219512195
TF TF:M03559 Factor: Pit-1; motif: NNWWATTCAT 0.014746683952348 5334 86 41 0.476744186046512 0.00768653918260217
TF TF:M10758 Factor: HOXB1; motif: NTCRTTAN 0.014746683952348 2781 21 11 0.523809523809524 0.00395541172240201
TF TF:M03823_1 Factor: FOXO1A; motif: AAACAA; match class: 1 0.014746683952348 9098 116 75 0.646551724137931 0.008243570015388
TF TF:M01883 Factor: IRF-4; motif: GAAARTA 0.014746683952348 8317 105 65 0.619047619047619 0.00781531802332572
TF TF:M10041 Factor: PRDM6; motif: NRRARGAAAAANA 0.014746683952348 2852 98 30 0.306122448979592 0.0105189340813464
TF TF:M00672_1 Factor: TEF; motif: ATGTTWAYATAA; match class: 1 0.014746683952348 1824 136 28 0.205882352941176 0.0153508771929825
TF TF:M12070_1 Factor: CIZ; motif: TTTTNNNNNNNNNNNNNAAAAA; match class: 1 0.014746683952348 2585 112 31 0.276785714285714 0.0119922630560928
TF TF:M03854_1 Factor: SRY; motif: TTGTTT; match class: 1 0.014746683952348 9098 116 75 0.646551724137931 0.008243570015388
TF TF:M02097 Factor: LHX3; motif: ATTAAW 0.0147603243199975 11840 103 81 0.786407766990291 0.00684121621621622
TF TF:M00347 Factor: GATA-1; motif: MNAGATAANR 0.0147603243199975 4571 132 51 0.386363636363636 0.0111572959964997
TF TF:M00489 Factor: Nkx6-2; motif: NWADTAAWTANN 0.0171814740760954 1779 120 25 0.208333333333333 0.014052838673412
TF TF:M07213_1 Factor: GATA2; motif: NNNTTCTTATCTSN; match class: 1 0.0178493700937544 482 10 4 0.4 0.00829875518672199
TF TF:M00346 Factor: GATA-1; motif: NCWGATAACA 0.0178493700937544 4376 98 39 0.397959183673469 0.00891224862888483
TF TF:M11005_1 Factor: LHX4; motif: NNCRTTAN; match class: 1 0.0179383351105719 4203 109 41 0.376146788990826 0.00975493694979776
TF TF:M08220 Factor: Elk-1:HOXA3; motif: ACCGGWAATKRNNTNWCNNATTAN 0.0179383351105719 12140 116 91 0.78448275862069 0.00749588138385502
TF TF:M10591 Factor: BSX; motif: NNCGTTAN 0.0179383351105719 7760 132 74 0.560606060606061 0.0095360824742268
TF TF:M11725_1 Factor: B-Myb; motif: NTAACSGTYRN; match class: 1 0.0183845535049862 169 120 7 0.0583333333333333 0.0414201183431953
TF TF:M01971 Factor: LHX3b; motif: AATTAATTWN 0.0189487357785067 862 135 17 0.125925925925926 0.0197215777262181
TF TF:M01412 Factor: Msx-1; motif: NNNNANTAATTANTNN 0.0192080681111897 3098 136 39 0.286764705882353 0.012588766946417
TF TF:M10695_1 Factor: HOXA6; motif: RTCRTTAN; match class: 1 0.0222199408438607 1493 139 24 0.172661870503597 0.0160750167448091
TF TF:M10706 Factor: HoxA5; motif: NYMATTAN 0.0222199408438607 3532 114 37 0.324561403508772 0.010475651189128
TF TF:M10705_1 Factor: HoxA5; motif: GYMATTAS; match class: 1 0.0222199408438607 3532 114 37 0.324561403508772 0.010475651189128
TF TF:M10705 Factor: HoxA5; motif: GYMATTAS 0.0222199408438607 3532 114 37 0.324561403508772 0.010475651189128
TF TF:M00485 Factor: Nkx2-2; motif: TTAAGTRSTT 0.0222199408438607 2603 135 34 0.251851851851852 0.0130618517095659
TF TF:M10586 Factor: Barx-2; motif: NWWAAYCATTAN 0.0222199408438607 1016 97 15 0.154639175257732 0.0147637795275591
TF TF:M10703 Factor: HoxA5; motif: NYAATTAN 0.0222199408438607 3532 114 37 0.324561403508772 0.010475651189128
TF TF:M11913 Factor: POU3F2; motif: TAATTANNNNNNTAATTA 0.0242057570170106 4085 20 12 0.6 0.002937576499388
TF TF:M01431_1 Factor: Barx-2; motif: TAANTAATTANTKNTN; match class: 1 0.0242057570170106 1466 101 19 0.188118811881188 0.0129604365620737
TF TF:M01321_1 Factor: HOXC-8; motif: NNNNNGTAATTANNNT; match class: 1 0.0244797171126517 4392 136 49 0.360294117647059 0.0111566484517304
TF TF:M10727 Factor: HOXB8; motif: RTCRTTAN 0.0244797171126517 6289 116 56 0.482758620689655 0.00890443631737955
TF TF:M09938 Factor: GATA-3; motif: NNAGATAANAN 0.0244797171126517 3184 132 38 0.287878787878788 0.0119346733668342
TF TF:M00465 Factor: POU6F1; motif: GCATAAWTTAT 0.0244797171126517 1511 140 24 0.171428571428571 0.0158835208471211
TF TF:M01383 Factor: Nkx3A; motif: NNNNAAGTACTTAAANN 0.0244797171126517 2745 136 35 0.257352941176471 0.0127504553734062
TF TF:M01859 Factor: AP-2; motif: NNGCCTK 0.0244797171126517 7799 23 18 0.782608695652174 0.00230798820361585
TF TF:M01124_1 Factor: Oct-4; motif: ATTGWSWTGCWAAWN; match class: 1 0.0244797171126517 1757 114 23 0.201754385964912 0.0130904951622083
TF TF:M00137 Factor: Oct-1; motif: NNNRTAATNANNN 0.0244797171126517 6851 117 60 0.512820512820513 0.00875784556998978
TF TF:M11932 Factor: Oct3; motif: NNTTATGYWAATKARN 0.0244797171126517 4744 140 53 0.378571428571429 0.0111720067453626
TF TF:M01878_1 Factor: GATA-3; motif: AGATAA; match class: 1 0.0261836527067186 4168 136 47 0.345588235294118 0.0112763915547025
TF TF:M03559_1 Factor: Pit-1; motif: NNWWATTCAT; match class: 1 0.0277776241809882 1384 101 18 0.178217821782178 0.0130057803468208
TF TF:M04393 Factor: LMX1B; motif: NYAATTAN 0.028808202150899 2301 85 22 0.258823529411765 0.00956106040851804
TF TF:M10685 Factor: HOXB7; motif: NGYAATTANN 0.0295327967713337 3549 121 38 0.31404958677686 0.0107072414764722
TF TF:M08220_1 Factor: Elk-1:HOXA3; motif: ACCGGWAATKRNNTNWCNNATTAN; match class: 1 0.0295327967713337 5350 115 49 0.426086956521739 0.0091588785046729
TF TF:M01872 Factor: DBP; motif: TTWTGYAA 0.0295734656366116 2691 141 35 0.24822695035461 0.0130063173541434
TF TF:M04443 Factor: UNCX; motif: NYAATTAN 0.0295734656366116 3248 114 34 0.298245614035088 0.0104679802955665
TF TF:M08918 Factor: GATA-3; motif: WGATAASN 0.0295734656366116 4301 137 48 0.35036496350365 0.0111601953034178
TF TF:M11272 Factor: JunB; motif: NATGASTCAYN 0.0295734656366116 799 116 14 0.120689655172414 0.0175219023779725
TF TF:M03997 Factor: GATA3; motif: NGATAANN 0.0295734656366116 4301 137 48 0.35036496350365 0.0111601953034178
TF TF:M11554_1 Factor: HFH2; motif: NYWAYRTAAACA; match class: 1 0.0295734656366116 789 9 4 0.444444444444444 0.00506970849176172
TF TF:M04392 Factor: LMX1A; motif: NTAATTAA 0.0295734656366116 2581 114 29 0.254385964912281 0.0112359550561798
TF TF:M01452 Factor: HOXA5; motif: ANGNTAATTANCNNAN 0.02980069909928 3709 109 36 0.330275229357798 0.00970612024804529
TF TF:M10801 Factor: HOXA10; motif: NRTCGTAAANN 0.0311112363064649 3886 5 5 1 0.00128667009778693
TF TF:M08692 Factor: ERF:pitx1; motif: NNCGGAWGNNNRGNTTA 0.0326953559383041 5359 65 31 0.476923076923077 0.00578466131740996
TF TF:M04399 Factor: MEOX2; motif: NSTAATTANN 0.0326953559383041 3837 114 38 0.333333333333333 0.00990357049778473
TF TF:M00423_1 Factor: FOXJ2; motif: AYMATAATATTTKN; match class: 1 0.0330339358756988 2755 114 30 0.263157894736842 0.0108892921960073
TF TF:M10591_1 Factor: BSX; motif: NNCGTTAN; match class: 1 0.0330339358756988 2259 113 26 0.230088495575221 0.0115095174856131
TF TF:M10956_1 Factor: isx; motif: NTCRTTAA; match class: 1 0.0330339358756988 3336 113 34 0.300884955752212 0.0101918465227818
TF TF:M00040_1 Factor: ATF-2; motif: TTACGTAA; match class: 1 0.0330339358756988 6460 136 64 0.470588235294118 0.00990712074303406
TF TF:M08190_1 Factor: AR; motif: GGAACGGWACATGTTCT; match class: 1 0.0330339358756988 2001 15 7 0.466666666666667 0.00349825087456272
TF TF:M08836 Factor: OCT-2; motif: ATGMATATGCWAAT 0.0330339358756988 3691 12 8 0.666666666666667 0.00216743429964779
TF TF:M02027 Factor: PARP; motif: TTTCYN 0.0330339358756988 16377 117 110 0.94017094017094 0.00671673688709776
TF TF:M04711 Factor: PU.1; motif: ACTTCCTCT 0.0330339358756988 1712 131 24 0.183206106870229 0.014018691588785
TF TF:M03872_1 Factor: HNF-1beta; motif: GTTAATYATTAACY; match class: 1 0.0333899005581957 729 117 13 0.111111111111111 0.0178326474622771
TF TF:M01471 Factor: Lhx3; motif: NNAATTAATTAAWWNNN 0.0333899005581957 981 135 17 0.125925925925926 0.017329255861366
TF TF:M01438 Factor: ipf1; motif: NNRNTAATTAGYNCAN 0.0337130543729286 3325 136 39 0.286764705882353 0.0117293233082707
TF TF:M04052 Factor: NFATc1; motif: TTTCCAYWRTGGAAA 0.0344625236647643 6663 143 68 0.475524475524476 0.010205613087198
TF TF:M01383_1 Factor: Nkx3A; motif: NNNNAAGTACTTAAANN; match class: 1 0.0344625236647643 1216 131 19 0.145038167938931 0.015625
TF TF:M04556_1 Factor: SRY; motif: AACAATNNNCATTGTT; match class: 1 0.0344625236647643 6127 86 42 0.488372093023256 0.00685490452097274
TF TF:M08775_1 Factor: IRF-2; motif: NAANYGAAASYR; match class: 1 0.0344625236647643 2761 70 21 0.3 0.00760593987685621
TF TF:M10690 Factor: HOXA7; motif: GYMATTAN 0.0344625236647643 10748 114 80 0.701754385964912 0.00744324525493115
TF TF:M10615_1 Factor: Dlx-5; motif: NTCRTTAN; match class: 1 0.0407582466365689 730 136 14 0.102941176470588 0.0191780821917808
TF TF:M04557_1 Factor: SRY; motif: TCAATAMCATTGA; match class: 1 0.0421615412335361 5015 19 12 0.631578947368421 0.00239282153539382
TF TF:M04327_1 Factor: GSX1; motif: NNYMATTANN; match class: 1 0.0421615412335361 5540 115 49 0.426086956521739 0.00884476534296029
TF TF:M09976 Factor: LHX2; motif: NNYTAATTRNNN 0.0421615412335361 2364 135 30 0.222222222222222 0.0126903553299492
TF TF:M10785_1 Factor: hoxa9; motif: RTCGTWANNN; match class: 1 0.0421615412335361 1160 140 19 0.135714285714286 0.0163793103448276
TF TF:M11724_1 Factor: B-Myb; motif: NTRACSGTYNN; match class: 1 0.0421615412335361 1158 88 14 0.159090909090909 0.0120898100172712
TF TF:M11724 Factor: B-Myb; motif: NTRACSGTYNN 0.0421615412335361 1158 88 14 0.159090909090909 0.0120898100172712
TF TF:M04327 Factor: GSX1; motif: NNYMATTANN 0.0430276751541855 5709 115 50 0.434782608695652 0.00875810124365038
TF TF:M11276 Factor: XBP-1; motif: NNMCACGTCANN 0.0430276751541855 551 103 10 0.0970873786407767 0.0181488203266788
TF TF:M03962_1 Factor: E2F-3; motif: NNTTTTGGCGCCAAAACT; match class: 1 0.0430276751541855 6518 73 38 0.520547945205479 0.00583000920527769
TF TF:M06160 Factor: ZNF92; motif: NGWTGMGGWWGM 0.0430650929032702 122 63 4 0.0634920634920635 0.0327868852459016
TF TF:M10880_1 Factor: Alx-4; motif: NNCRTTAN; match class: 1 0.0430650929032702 2683 32 12 0.375 0.00447260529258293
TF TF:M04402 Factor: MIXL1; motif: NNYAATTANN 0.0446635366631174 2460 114 27 0.236842105263158 0.0109756097560976
TF TF:M10683 Factor: HOXB7; motif: GTCRTTAN 0.0446635366631174 1643 25 8 0.32 0.00486914181375533
TF TF:M01412_1 Factor: Msx-1; motif: NNNNANTAATTANTNN; match class: 1 0.0446635366631174 1264 101 16 0.158415841584158 0.0126582278481013
TF TF:M04328_1 Factor: GSX2; motif: NNYMATTANN; match class: 1 0.0446635366631174 3836 114 37 0.324561403508772 0.00964546402502607
TF TF:M11586 Factor: foxj3; motif: ACGTAAACAN 0.0447907623423853 1252 32 8 0.25 0.00638977635782748
TF TF:M11330 Factor: Hlf; motif: NGTTRYGYAANN 0.0448663477868579 1046 38 8 0.210526315789474 0.00764818355640535
TF TF:M03216_1 Factor: GATA-6; motif: AGATAAN; match class: 1 0.0448663477868579 378 10 3 0.3 0.00793650793650794
TF TF:M11894 Factor: Oct-2; motif: NNNATTATGCAW 0.0448663477868579 3739 41 17 0.414634146341463 0.00454667023268254
TF TF:M10690_1 Factor: HOXA7; motif: GYMATTAN; match class: 1 0.0448663477868579 6126 114 52 0.456140350877193 0.00848841005550114
TF TF:M00789_1 Factor: GATA; motif: WGATARN; match class: 1 0.0448663477868579 378 10 3 0.3 0.00793650793650794
TF TF:M07425_1 Factor: Msx-2; motif: TAATTAN; match class: 1 0.0448663477868579 1333 135 20 0.148148148148148 0.0150037509377344
TF TF:M09770 Factor: FOXK2; motif: NNGTAAACANN 0.0448663477868579 958 32 7 0.21875 0.00730688935281837
TF TF:M07214_1 Factor: GATA3; motif: AGATAAGA; match class: 1 0.0448663477868579 378 10 3 0.3 0.00793650793650794
TF TF:M10692_1 Factor: HOXB6; motif: GTCGTTAN; match class: 1 0.0448663477868579 1009 139 17 0.122302158273381 0.0168483647175421
TF TF:M08765_1 Factor: GATA-1; motif: NGATAAN; match class: 1 0.0448663477868579 378 10 3 0.3 0.00793650793650794
TF TF:M10716 Factor: HOXA4; motif: RTMATTAN 0.0457802718323647 4050 113 38 0.336283185840708 0.00938271604938272
TF TF:M04713_1 Factor: GATA-1; motif: CCTTATCTS; match class: 1 0.0457802718323647 383 10 3 0.3 0.00783289817232376
TF TF:M00095_1 Factor: CDP; motif: CCAATAATCGAT; match class: 1 0.0463580274391035 2983 101 28 0.277227722772277 0.00938652363392558
TF TF:M08800 Factor: ARNT; motif: YRCGTGNN 0.0472521254826455 914 44 8 0.181818181818182 0.0087527352297593
TF TF:M04555 Factor: SRY; motif: AACAATANCATTGTT 0.0480244407963747 7098 89 47 0.528089887640449 0.00662158354466047
TF TF:M01431 Factor: Barx-2; motif: TAANTAATTANTKNTN 0.0480244407963747 2185 136 28 0.205882352941176 0.0128146453089245
TF TF:M03962 Factor: E2F-3; motif: NNTTTTGGCGCCAAAACT 0.0480244407963747 11119 63 48 0.761904761904762 0.00431693497616692
TF TF:M10625 Factor: Nkx3-2; motif: NTCGTTAN 0.0490789912613549 6062 132 58 0.439393939393939 0.00956779940613659
TF TF:M10638_1 Factor: Nkx2-3; motif: NNCGTTRWS; match class: 1 0.0490789912613549 4099 120 40 0.333333333333333 0.00975847767748231
TF TF:M08822 Factor: Msx-1; motif: WNGNAATTANV 0.0490789912613549 6821 90 46 0.511111111111111 0.00674387919659874
TF TF:M10750_1 Factor: gsh-1; motif: NTMATNRN; match class: 1 0.0494369225157067 3954 136 43 0.316176470588235 0.0108750632271118
TF TF:M11588 Factor: FOXK1; motif: NWYGTAAAYAR 0.0494776409863407 5352 142 56 0.394366197183099 0.0104633781763827
TF TF:M10625_1 Factor: Nkx3-2; motif: NTCGTTAN; match class: 1 0.0494776409863407 1314 32 8 0.25 0.0060882800608828
TF TF:M10824 Factor: HOXD11; motif: NRTCGTAAANNKTWAN 0.0494776409863407 277 54 5 0.0925925925925926 0.0180505415162455
TF TF:M01235 Factor: ipf1; motif: NVSTAATTAC 0.0495706346233988 3518 113 34 0.300884955752212 0.00966458214894827
TF TF:M08394 Factor: PBX4:HOXA1; motif: NYNATMAATCA 0.0495706346233988 1502 7 4 0.571428571428571 0.00266311584553928
TF TF:M04303 Factor: Dlx-5; motif: NYAATTAN 0.0495706346233988 937 127 15 0.118110236220472 0.016008537886873
TF TF:M10619 Factor: Dlx-2; motif: NYAATTAN 0.0495706346233988 937 127 15 0.118110236220472 0.016008537886873
TF TF:M00148 Factor: SRY; motif: AAACWAM 0.0495706346233988 9455 72 48 0.666666666666667 0.00507667900581703
TF TF:M10620 Factor: Dlx-2; motif: NYAATTAN 0.0495706346233988 937 127 15 0.118110236220472 0.016008537886873
TF TF:M10602 Factor: Dlx-7; motif: NYAATTAN 0.0495706346233988 937 127 15 0.118110236220472 0.016008537886873
TF TF:M10604 Factor: Dlx-7; motif: NYAATTAN 0.0495706346233988 937 127 15 0.118110236220472 0.016008537886873
TF TF:M10963 Factor: RHOXF1; motif: NGGATCAN 0.0495706346233988 2641 104 26 0.25 0.00984475577432791
TF TF:M03549 Factor: GATA-4; motif: AGATAAN 0.0495706346233988 4870 84 34 0.404761904761905 0.00698151950718686

pMA06 transcription factor target enrichment of top program genes

TF enrichment of pMA06
TFs corrosponding to activation of pMA06. (Left) pearson correlation of TF expression and gene expression program activatity in Mast cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.