pEpi27 program activity among Epithelial cells

Activation of pEpi27
pEpi27 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpi27 by different cell subtypes
pEpi27 gene program activation among cells of different subtypes (Epithelial cells).

pEpi27 top program genes

Top genes of pEpi27 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpi27 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpi27
pEpi27 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0032970 regulation of actin filament-based process 0.0126938804605901 406 38 7 0.184210526315789 0.0172413793103448
GO:BP GO:0010498 proteasomal protein catabolic process 0.0126938804605901 491 34 7 0.205882352941176 0.0142566191446029
GO:BP GO:0043412 macromolecule modification 0.0126938804605901 4257 28 17 0.607142857142857 0.00399342259807376
GO:BP GO:0010592 positive regulation of lamellipodium assembly 0.0126938804605901 29 37 3 0.0810810810810811 0.103448275862069
GO:BP GO:1902745 positive regulation of lamellipodium organization 0.0167597213764731 37 37 3 0.0810810810810811 0.0810810810810811
GO:BP GO:0036211 protein modification process 0.0167597213764731 4041 28 16 0.571428571428571 0.00395941598614204
GO:BP GO:0006464 cellular protein modification process 0.0167597213764731 4041 28 16 0.571428571428571 0.00395941598614204
GO:BP GO:0010591 regulation of lamellipodium assembly 0.0175930831973519 43 37 3 0.0810810810810811 0.0697674418604651
GO:BP GO:0043933 protein-containing complex subunit organization 0.0175930831973519 1963 47 15 0.319148936170213 0.0076413652572593
GO:BP GO:0044267 cellular protein metabolic process 0.0177607660911108 5229 28 18 0.642857142857143 0.00344234079173838
GO:BP GO:0006900 vesicle budding from membrane 0.0177607660911108 107 46 4 0.0869565217391304 0.0373831775700935
GO:BP GO:0042176 regulation of protein catabolic process 0.0177607660911108 401 6 3 0.5 0.00748129675810474
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 0.0177607660911108 434 34 6 0.176470588235294 0.0138248847926267
GO:BP GO:0070647 protein modification by small protein conjugation or removal 0.0177607660911108 1184 10 5 0.5 0.00422297297297297
GO:BP GO:1902743 regulation of lamellipodium organization 0.0177607660911108 55 37 3 0.0810810810810811 0.0545454545454545
GO:BP GO:0065003 protein-containing complex assembly 0.01869560915867 1680 47 13 0.276595744680851 0.00773809523809524
GO:BP GO:0110053 regulation of actin filament organization 0.0190494037712727 284 37 5 0.135135135135135 0.0176056338028169
GO:BP GO:0044237 cellular metabolic process 0.020149603157174 10871 25 23 0.92 0.00211572072486432
GO:BP GO:0019538 protein metabolic process 0.020149603157174 5808 28 18 0.642857142857143 0.00309917355371901
GO:BP GO:0051130 positive regulation of cellular component organization 0.020149603157174 1153 7 4 0.571428571428571 0.00346921075455334
GO:BP GO:0048193 Golgi vesicle transport 0.020149603157174 382 46 6 0.130434782608696 0.0157068062827225
GO:BP GO:0051603 proteolysis involved in cellular protein catabolic process 0.020149603157174 750 34 7 0.205882352941176 0.00933333333333333
GO:BP GO:0030163 protein catabolic process 0.020149603157174 974 34 8 0.235294117647059 0.0082135523613963
GO:BP GO:0030032 lamellipodium assembly 0.020149603157174 74 37 3 0.0810810810810811 0.0405405405405405
GO:BP GO:0044260 cellular macromolecule metabolic process 0.0202133214840232 8390 28 22 0.785714285714286 0.00262216924910608
GO:BP GO:0120032 regulation of plasma membrane bounded cell projection assembly 0.0221045040808686 190 37 4 0.108108108108108 0.0210526315789474
GO:BP GO:0008064 regulation of actin polymerization or depolymerization 0.0221045040808686 193 37 4 0.108108108108108 0.0207253886010363
GO:BP GO:0030832 regulation of actin filament length 0.0221045040808686 194 37 4 0.108108108108108 0.0206185567010309
GO:BP GO:0032446 protein modification by small protein conjugation 0.0221045040808686 973 55 10 0.181818181818182 0.0102774922918808
GO:BP GO:0060491 regulation of cell projection assembly 0.0221045040808686 192 37 4 0.108108108108108 0.0208333333333333
GO:BP GO:0044257 cellular protein catabolic process 0.0221045040808686 813 34 7 0.205882352941176 0.00861008610086101
GO:BP GO:0008154 actin polymerization or depolymerization 0.0231174270600615 223 37 4 0.108108108108108 0.0179372197309417
GO:BP GO:0072384 organelle transport along microtubule 0.0231174270600615 86 46 3 0.0652173913043478 0.0348837209302326
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.0231174270600615 366 37 5 0.135135135135135 0.0136612021857923
GO:BP GO:0090114 COPII-coated vesicle budding 0.0231174270600615 72 46 3 0.0652173913043478 0.0416666666666667
GO:BP GO:0070936 protein K48-linked ubiquitination 0.0231174270600615 61 55 3 0.0545454545454545 0.0491803278688525
GO:BP GO:0033036 macromolecule localization 0.0231174270600615 3218 61 21 0.344262295081967 0.00652579241765072
GO:BP GO:0097581 lamellipodium organization 0.0231174270600615 91 37 3 0.0810810810810811 0.032967032967033
GO:BP GO:1902905 positive regulation of supramolecular fiber organization 0.0231174270600615 214 37 4 0.108108108108108 0.0186915887850467
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 0.0231174270600615 655 34 6 0.176470588235294 0.00916030534351145
GO:BP GO:0032535 regulation of cellular component size 0.0231174270600615 388 37 5 0.135135135135135 0.0128865979381443
GO:BP GO:1901564 organonitrogen compound metabolic process 0.0231174270600615 6792 28 19 0.678571428571429 0.00279740871613663
GO:BP GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 0.0231174270600615 106 37 3 0.0810810810810811 0.0283018867924528
GO:BP GO:0008104 protein localization 0.0231174270600615 2770 61 19 0.311475409836066 0.00685920577617329
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.0231174270600615 387 37 5 0.135135135135135 0.0129198966408269
GO:BP GO:0051495 positive regulation of cytoskeleton organization 0.0231174270600615 231 37 4 0.108108108108108 0.0173160173160173
GO:BP GO:0038093 Fc receptor signaling pathway 0.0231174270600615 238 37 4 0.108108108108108 0.0168067226890756
GO:BP GO:0031346 positive regulation of cell projection organization 0.0231174270600615 359 37 5 0.135135135135135 0.0139275766016713
GO:BP GO:0009057 macromolecule catabolic process 0.0231174270600615 1468 16 6 0.375 0.00408719346049046
GO:BP GO:0015980 energy derivation by oxidation of organic compounds 0.0231174270600615 289 27 4 0.148148148148148 0.013840830449827
GO:BP GO:0030029 actin filament-based process 0.0231174270600615 808 38 7 0.184210526315789 0.00866336633663366
GO:BP GO:0019941 modification-dependent protein catabolic process 0.0231174270600615 662 34 6 0.176470588235294 0.00906344410876133
GO:BP GO:0018193 peptidyl-amino acid modification 0.0233851735370169 1303 4 3 0.75 0.00230237912509593
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 0.0234180437059917 673 34 6 0.176470588235294 0.00891530460624071
GO:BP GO:0120035 regulation of plasma membrane bounded cell projection organization 0.0255337433121456 638 37 6 0.162162162162162 0.00940438871473354
GO:BP GO:0034645 cellular macromolecule biosynthetic process 0.0255337433121456 5051 24 14 0.583333333333333 0.00277172837061968
GO:BP GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 0.0265583900472294 206 46 4 0.0869565217391304 0.0194174757281553
GO:BP GO:0046907 intracellular transport 0.0265583900472294 1767 61 14 0.229508196721311 0.00792303338992643
GO:BP GO:0006996 organelle organization 0.0265583900472294 4104 47 20 0.425531914893617 0.00487329434697856
GO:BP GO:0009059 macromolecule biosynthetic process 0.0267350575481723 5114 24 14 0.583333333333333 0.00273758310520141
GO:BP GO:0007015 actin filament organization 0.0267430009575558 445 37 5 0.135135135135135 0.0112359550561798
GO:BP GO:0031344 regulation of cell projection organization 0.0267430009575558 656 37 6 0.162162162162162 0.00914634146341463
GO:BP GO:0018205 peptidyl-lysine modification 0.0277387771196004 405 12 3 0.25 0.00740740740740741
GO:BP GO:0051650 establishment of vesicle localization 0.0277387771196004 214 46 4 0.0869565217391304 0.0186915887850467
GO:BP GO:0042775 mitochondrial ATP synthesis coupled electron transport 0.0282716126246913 99 47 3 0.0638297872340425 0.0303030303030303
GO:BP GO:0042773 ATP synthesis coupled electron transport 0.0284467892994686 100 47 3 0.0638297872340425 0.03
GO:BP GO:0008152 metabolic process 0.0291934893689573 11827 25 23 0.92 0.00194470279868098
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.0291934893689573 460 37 5 0.135135135135135 0.0108695652173913
GO:BP GO:0022900 electron transport chain 0.0304663618458598 180 57 4 0.0701754385964912 0.0222222222222222
GO:BP GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 0.0309534327459906 135 37 3 0.0810810810810811 0.0222222222222222
GO:BP GO:0038094 Fc-gamma receptor signaling pathway 0.0309534327459906 137 37 3 0.0810810810810811 0.0218978102189781
GO:BP GO:0034446 substrate adhesion-dependent cell spreading 0.0309534327459906 109 46 3 0.0652173913043478 0.0275229357798165
GO:BP GO:0051648 vesicle localization 0.0309534327459906 230 46 4 0.0869565217391304 0.0173913043478261
GO:BP GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 0.0309534327459906 135 37 3 0.0810810810810811 0.0222222222222222
GO:BP GO:0006807 nitrogen compound metabolic process 0.0311579130857428 10078 25 21 0.84 0.0020837467751538
GO:BP GO:0002431 Fc receptor mediated stimulatory signaling pathway 0.0329938044117581 141 37 3 0.0810810810810811 0.0212765957446809
GO:BP GO:1901565 organonitrogen compound catabolic process 0.0336123006750796 1358 34 8 0.235294117647059 0.00589101620029455
GO:BP GO:0009894 regulation of catabolic process 0.034047258039781 1033 6 3 0.5 0.00290416263310745
GO:BP GO:0010720 positive regulation of cell development 0.034047258039781 302 37 4 0.108108108108108 0.0132450331125828
GO:BP GO:0032880 regulation of protein localization 0.0343372306772026 922 13 4 0.307692307692308 0.00433839479392625
GO:BP GO:0022904 respiratory electron transport chain 0.0347007323581459 117 47 3 0.0638297872340425 0.0256410256410256
GO:BP GO:0034622 cellular protein-containing complex assembly 0.0353691160305035 1107 61 10 0.163934426229508 0.00903342366757001
GO:BP GO:0043413 macromolecule glycosylation 0.0360950858087588 251 23 3 0.130434782608696 0.0119521912350598
GO:BP GO:0006486 protein glycosylation 0.0360950858087588 251 23 3 0.130434782608696 0.0119521912350598
GO:BP GO:0090066 regulation of anatomical structure size 0.036296122602282 518 37 5 0.135135135135135 0.00965250965250965
GO:BP GO:0044249 cellular biosynthetic process 0.0371549788841663 6154 24 15 0.625 0.0024374390640234
GO:BP GO:0015031 protein transport 0.0387702829704347 1929 61 14 0.229508196721311 0.00725764644893727
GO:BP GO:0016032 viral process 0.0387702829704347 942 7 3 0.428571428571429 0.00318471337579618
GO:BP GO:0045927 positive regulation of growth 0.0388391381646369 274 22 3 0.136363636363636 0.0109489051094891
GO:BP GO:0051493 regulation of cytoskeleton organization 0.0388391381646369 531 37 5 0.135135135135135 0.00941619585687382
GO:BP GO:0070085 glycosylation 0.0391301056859916 264 23 3 0.130434782608696 0.0113636363636364
GO:BP GO:0070972 protein localization to endoplasmic reticulum 0.0391301056859916 146 41 3 0.0731707317073171 0.0205479452054795
GO:BP GO:0010256 endomembrane system organization 0.039145876532816 484 13 3 0.230769230769231 0.00619834710743802
GO:BP GO:0034613 cellular protein localization 0.0391828464624444 2014 59 14 0.23728813559322 0.00695134061569017
GO:BP GO:1901576 organic substance biosynthetic process 0.0397623690466357 6248 24 15 0.625 0.00240076824583867
GO:BP GO:0070727 cellular macromolecule localization 0.0397623690466357 2024 59 14 0.23728813559322 0.00691699604743083
GO:BP GO:0044403 biological process involved in symbiotic interaction 0.0411569066846211 1001 7 3 0.428571428571429 0.002997002997003
GO:BP GO:0016567 protein ubiquitination 0.0413795766915683 892 55 8 0.145454545454545 0.00896860986547085
GO:BP GO:0030833 regulation of actin filament polymerization 0.0413795766915683 177 37 3 0.0810810810810811 0.0169491525423729
GO:BP GO:0040007 growth 0.0413795766915683 967 22 5 0.227272727272727 0.00517063081695967
GO:BP GO:0042886 amide transport 0.0413795766915683 2007 61 14 0.229508196721311 0.00697558545092177
GO:BP GO:0016050 vesicle organization 0.0413795766915683 341 61 5 0.0819672131147541 0.0146627565982405
GO:BP GO:0015833 peptide transport 0.0413795766915683 1971 61 14 0.229508196721311 0.00710299340436327
GO:BP GO:0006281 DNA repair 0.0413795766915683 576 12 3 0.25 0.00520833333333333
GO:BP GO:0007030 Golgi organization 0.0413795766915683 147 46 3 0.0652173913043478 0.0204081632653061
GO:BP GO:0009058 biosynthetic process 0.0413795766915683 6340 24 15 0.625 0.00236593059936909
GO:BP GO:0044085 cellular component biogenesis 0.0413795766915683 3257 47 16 0.340425531914894 0.00491249616211237
GO:BP GO:0033554 cellular response to stress 0.0413795766915683 2111 25 8 0.32 0.00378967314069162
GO:BP GO:0044238 primary metabolic process 0.0413795766915683 10584 25 21 0.84 0.00198412698412698
GO:BP GO:0048522 positive regulation of cellular process 0.0413795766915683 5757 7 6 0.857142857142857 0.00104220948410631
GO:BP GO:0051656 establishment of organelle localization 0.0413795766915683 445 46 5 0.108695652173913 0.0112359550561798
GO:BP GO:0043170 macromolecule metabolic process 0.0428845437710901 9796 28 22 0.785714285714286 0.00224581461821152
GO:BP GO:0019058 viral life cycle 0.0431403095311154 353 61 5 0.0819672131147541 0.0141643059490085
GO:BP GO:0045184 establishment of protein localization 0.0431433078146311 2035 61 14 0.229508196721311 0.00687960687960688
GO:BP GO:0006091 generation of precursor metabolites and energy 0.0431433078146311 538 57 6 0.105263157894737 0.0111524163568773
GO:BP GO:0007005 mitochondrion organization 0.0436171918181958 561 55 6 0.109090909090909 0.0106951871657754
GO:BP GO:0044265 cellular macromolecule catabolic process 0.0439754261159434 1231 34 7 0.205882352941176 0.00568643379366369
GO:BP GO:1901575 organic substance catabolic process 0.0440508026307637 2267 34 10 0.294117647058824 0.00441111601235112
GO:BP GO:0022607 cellular component assembly 0.0450565919908241 3010 47 15 0.319148936170213 0.00498338870431894
GO:BP GO:0030041 actin filament polymerization 0.0453831281873522 196 37 3 0.0810810810810811 0.0153061224489796
GO:BP GO:0051223 regulation of protein transport 0.0460566793570157 586 13 3 0.230769230769231 0.00511945392491468
GO:BP GO:0006909 phagocytosis 0.0466538476830637 387 37 4 0.108108108108108 0.0103359173126615
GO:BP GO:0032386 regulation of intracellular transport 0.0467674569619967 367 61 5 0.0819672131147541 0.0136239782016349
GO:BP GO:0051128 regulation of cellular component organization 0.0468066604040881 2412 7 4 0.571428571428571 0.00165837479270315
GO:BP GO:0040008 regulation of growth 0.0476480946174152 681 22 4 0.181818181818182 0.00587371512481645
GO:BP GO:0070201 regulation of establishment of protein localization 0.0476480946174152 611 13 3 0.230769230769231 0.00490998363338789
GO:BP GO:0010970 transport along microtubule 0.0476480946174152 164 46 3 0.0652173913043478 0.0182926829268293
GO:BP GO:0090087 regulation of peptide transport 0.0482343722209416 618 13 3 0.230769230769231 0.00485436893203883
GO:BP GO:0071705 nitrogen compound transport 0.0482343722209416 2322 61 15 0.245901639344262 0.00645994832041344
GO:BP GO:0009101 glycoprotein biosynthetic process 0.0493348994720226 347 23 3 0.130434782608696 0.00864553314121038
GO:BP GO:0048518 positive regulation of biological process 0.0493348994720226 6363 7 6 0.857142857142857 0.000942951438000943
GO:CC GO:0043227 membrane-bounded organelle 0.000772074531508408 12858 47 45 0.957446808510638 0.00349976668222119
GO:CC GO:0043229 intracellular organelle 0.000772074531508408 12491 47 44 0.936170212765957 0.00352253622608278
GO:CC GO:1902494 catalytic complex 0.000772074531508408 1441 54 15 0.277777777777778 0.0104094378903539
GO:CC GO:0005654 nucleoplasm 0.00078962329315413 4102 45 23 0.511111111111111 0.00560702096538274
GO:CC GO:0031981 nuclear lumen 0.00078962329315413 4444 37 21 0.567567567567568 0.00472547254725473
GO:CC GO:0031090 organelle membrane 0.0012572341363953 3612 55 24 0.436363636363636 0.00664451827242525
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.00129668356885131 11296 47 41 0.872340425531915 0.00362960339943343
GO:CC GO:0032991 protein-containing complex 0.00129668356885131 5548 37 23 0.621621621621622 0.00414563806777217
GO:CC GO:0005737 cytoplasm 0.00251328085863966 11911 57 49 0.859649122807018 0.00411384434556292
GO:CC GO:0043226 organelle 0.00251328085863966 14008 47 45 0.957446808510638 0.00321245002855511
GO:CC GO:0005622 intracellular anatomical structure 0.00251328085863966 14790 48 47 0.979166666666667 0.00317782285327924
GO:CC GO:0070469 respirasome 0.00262347835672078 103 47 4 0.0851063829787234 0.0388349514563107
GO:CC GO:0043228 non-membrane-bounded organelle 0.00303816546109382 5346 34 20 0.588235294117647 0.00374111485222596
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.00303816546109382 5338 34 20 0.588235294117647 0.00374672161858374
GO:CC GO:0070013 intracellular organelle lumen 0.00437272484982004 5402 37 21 0.567567567567568 0.00388744909292854
GO:CC GO:1990234 transferase complex 0.00579516091031873 804 54 9 0.166666666666667 0.0111940298507463
GO:CC GO:0043233 organelle lumen 0.0059491132949304 5565 37 21 0.567567567567568 0.00377358490566038
GO:CC GO:0031974 membrane-enclosed lumen 0.0059491132949304 5565 37 21 0.567567567567568 0.00377358490566038
GO:CC GO:0140534 endoplasmic reticulum protein-containing complex 0.00602732215922521 128 23 3 0.130434782608696 0.0234375
GO:CC GO:0098796 membrane protein complex 0.00635341036658414 1322 11 5 0.454545454545455 0.0037821482602118
GO:CC GO:0005829 cytosol 0.0065760680017888 5303 34 19 0.558823529411765 0.00358287761644352
GO:CC GO:0005730 nucleolus 0.00782395548315231 955 31 7 0.225806451612903 0.00732984293193717
GO:CC GO:0031984 organelle subcompartment 0.00850249679110522 1773 46 12 0.260869565217391 0.00676818950930626
GO:CC GO:0016604 nuclear body 0.0102863870773636 816 28 6 0.214285714285714 0.00735294117647059
GO:CC GO:0098791 Golgi apparatus subcompartment 0.0106829177796056 885 46 8 0.173913043478261 0.00903954802259887
GO:CC GO:0012505 endomembrane system 0.0117836867804342 4640 55 24 0.436363636363636 0.00517241379310345
GO:CC GO:0005746 mitochondrial respirasome 0.0117836867804342 89 47 3 0.0638297872340425 0.0337078651685393
GO:CC GO:0031975 envelope 0.0153804428194161 1237 53 10 0.188679245283019 0.00808407437348424
GO:CC GO:0031967 organelle envelope 0.0153804428194161 1237 53 10 0.188679245283019 0.00808407437348424
GO:CC GO:0005783 endoplasmic reticulum 0.0162632593736224 1982 46 12 0.260869565217391 0.00605449041372351
GO:CC GO:0000139 Golgi membrane 0.0165324046420566 771 46 7 0.152173913043478 0.00907911802853437
GO:CC GO:0005789 endoplasmic reticulum membrane 0.0174189689383732 1117 25 6 0.24 0.0053715308863026
GO:CC GO:0098827 endoplasmic reticulum subcompartment 0.0174189689383732 1122 25 6 0.24 0.0053475935828877
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 0.0183523458603629 1139 25 6 0.24 0.00526777875329236
GO:CC GO:0031461 cullin-RING ubiquitin ligase complex 0.0190086381130992 166 34 3 0.0882352941176471 0.0180722891566265
GO:CC GO:0005794 Golgi apparatus 0.0244513840946893 1623 46 10 0.217391304347826 0.00616142945163278
GO:CC GO:0098800 inner mitochondrial membrane protein complex 0.0254529642060418 146 47 3 0.0638297872340425 0.0205479452054795
GO:CC GO:0140513 nuclear protein-containing complex 0.0288176820123899 1249 19 5 0.263157894736842 0.00400320256204964
GO:CC GO:0005743 mitochondrial inner membrane 0.0312928729858273 503 47 5 0.106382978723404 0.0099403578528827
GO:CC GO:0070062 extracellular exosome 0.0318009428056295 2176 8 4 0.5 0.00183823529411765
GO:CC GO:0016607 nuclear speck 0.0320247272658606 412 58 5 0.0862068965517241 0.0121359223300971
GO:CC GO:0005925 focal adhesion 0.0330052195239004 420 37 4 0.108108108108108 0.00952380952380952
GO:CC GO:1903561 extracellular vesicle 0.0337848222863487 2261 8 4 0.5 0.00176912870411322
GO:CC GO:0043230 extracellular organelle 0.0337848222863487 2263 8 4 0.5 0.00176756517896597
GO:CC GO:0030055 cell-substrate junction 0.0337848222863487 427 37 4 0.108108108108108 0.00936768149882904
GO:CC GO:0031965 nuclear membrane 0.0337848222863487 298 53 4 0.0754716981132075 0.0134228187919463
GO:CC GO:0031966 mitochondrial membrane 0.0341594535880912 746 47 6 0.127659574468085 0.00804289544235925
GO:CC GO:0099080 supramolecular complex 0.0341594535880912 1323 13 4 0.307692307692308 0.00302343159486017
GO:CC GO:0140535 intracellular protein-containing complex 0.0370588002663442 767 34 5 0.147058823529412 0.00651890482398957
GO:CC GO:0005634 nucleus 0.039365167322193 7592 45 26 0.577777777777778 0.00342465753424658
GO:CC GO:0019866 organelle inner membrane 0.0397537181334403 564 47 5 0.106382978723404 0.00886524822695036
GO:CC GO:0005740 mitochondrial envelope 0.0401686497043475 797 47 6 0.127659574468085 0.00752823086574655
GO:CC GO:0005768 endosome 0.0401686497043475 987 61 8 0.131147540983607 0.00810536980749747
GO:CC GO:0005769 early endosome 0.0401686497043475 378 46 4 0.0869565217391304 0.0105820105820106
GO:CC GO:0098687 chromosomal region 0.0402342578684783 354 27 3 0.111111111111111 0.00847457627118644
GO:CC GO:0000151 ubiquitin ligase complex 0.0455396017236964 297 34 3 0.0882352941176471 0.0101010101010101
GO:CC GO:0030133 transport vesicle 0.0490284193509709 414 46 4 0.0869565217391304 0.00966183574879227
GO:CC GO:0005694 chromosome 0.0495859794564089 2071 15 5 0.333333333333333 0.00241429261226461
GO:MF GO:0009055 electron transfer activity 0.0281333672464589 148 57 4 0.0701754385964912 0.027027027027027
GO:MF GO:0019899 enzyme binding 0.0281333672464589 2074 30 10 0.333333333333333 0.00482160077145612
GO:MF GO:0004721 phosphoprotein phosphatase activity 0.0295329158977198 188 27 3 0.111111111111111 0.0159574468085106
GO:MF GO:0044877 protein-containing complex binding 0.0322860666619837 1287 37 8 0.216216216216216 0.00621600621600622
GO:MF GO:0016791 phosphatase activity 0.0410905462441619 289 27 3 0.111111111111111 0.0103806228373702
GO:MF GO:0051015 actin filament binding 0.0412793127029823 212 37 3 0.0810810810810811 0.0141509433962264
HPA HPA:0170053 endometrium 2; glandular cells[High] 0.0257171461496309 1282 11 7 0.636363636363636 0.00546021840873635
HPA HPA:0170253 endometrium 2; cells in endometrial stroma[High] 0.030772822076203 326 5 3 0.6 0.00920245398773006
HPA HPA:0510653 soft tissue 2; fibroblasts[High] 0.030772822076203 481 4 3 0.75 0.00623700623700624
HPA HPA:0380513 placenta; decidual cells[High] 0.030772822076203 1144 10 6 0.6 0.00524475524475524
MIRNA MIRNA:hsa-miR-380-3p hsa-miR-380-3p 0.0111261262409732 76 56 5 0.0892857142857143 0.0657894736842105
MIRNA MIRNA:hsa-miR-466 hsa-miR-466 0.0121330779752509 169 50 6 0.12 0.0355029585798817
MIRNA MIRNA:hsa-miR-494-3p hsa-miR-494-3p 0.0197391851270966 135 28 4 0.142857142857143 0.0296296296296296
MIRNA MIRNA:hsa-miR-32-3p hsa-miR-32-3p 0.0197391851270966 123 31 4 0.129032258064516 0.032520325203252
MIRNA MIRNA:hsa-miR-5692a hsa-miR-5692a 0.0197391851270966 289 40 6 0.15 0.0207612456747405
MIRNA MIRNA:hsa-miR-8076 hsa-miR-8076 0.0197391851270966 79 17 3 0.176470588235294 0.0379746835443038
MIRNA MIRNA:hsa-miR-3688-3p hsa-miR-3688-3p 0.0197391851270966 114 13 3 0.230769230769231 0.0263157894736842
MIRNA MIRNA:hsa-miR-5683 hsa-miR-5683 0.0249192792352736 97 17 3 0.176470588235294 0.0309278350515464
MIRNA MIRNA:hsa-miR-379-3p hsa-miR-379-3p 0.0281868258629108 83 56 4 0.0714285714285714 0.0481927710843374
MIRNA MIRNA:hsa-miR-888-5p hsa-miR-888-5p 0.0281868258629108 76 61 4 0.0655737704918033 0.0526315789473684
MIRNA MIRNA:hsa-miR-330-3p hsa-miR-330-3p 0.0302466955211822 146 14 3 0.214285714285714 0.0205479452054795
MIRNA MIRNA:hsa-miR-6878-5p hsa-miR-6878-5p 0.0308705195721834 248 39 5 0.128205128205128 0.0201612903225806
MIRNA MIRNA:hsa-miR-580-5p hsa-miR-580-5p 0.0308705195721834 89 59 4 0.0677966101694915 0.0449438202247191
MIRNA MIRNA:hsa-miR-5681a hsa-miR-5681a 0.0308705195721834 137 39 4 0.102564102564103 0.0291970802919708
MIRNA MIRNA:hsa-miR-7856-5p hsa-miR-7856-5p 0.0308705195721834 135 39 4 0.102564102564103 0.0296296296296296
MIRNA MIRNA:hsa-miR-3074-3p hsa-miR-3074-3p 0.0308705195721834 59 36 3 0.0833333333333333 0.0508474576271186
MIRNA MIRNA:hsa-miR-4503 hsa-miR-4503 0.0318582678929664 70 33 3 0.0909090909090909 0.0428571428571429
MIRNA MIRNA:hsa-miR-4717-3p hsa-miR-4717-3p 0.0326804252780449 78 31 3 0.0967741935483871 0.0384615384615385
MIRNA MIRNA:hsa-miR-497-3p hsa-miR-497-3p 0.0326804252780449 99 57 4 0.0701754385964912 0.0404040404040404
MIRNA MIRNA:hsa-miR-7850-5p hsa-miR-7850-5p 0.0343914214690775 98 61 4 0.0655737704918033 0.0408163265306122
MIRNA MIRNA:hsa-miR-484 hsa-miR-484 0.0343914214690775 890 8 4 0.5 0.00449438202247191
MIRNA MIRNA:hsa-miR-15b-5p hsa-miR-15b-5p 0.0343914214690775 760 49 9 0.183673469387755 0.0118421052631579
MIRNA MIRNA:hsa-miR-3065-5p hsa-miR-3065-5p 0.0343914214690775 126 48 4 0.0833333333333333 0.0317460317460317
MIRNA MIRNA:hsa-miR-488-3p hsa-miR-488-3p 0.0358227830526408 131 48 4 0.0833333333333333 0.0305343511450382
MIRNA MIRNA:hsa-miR-877-5p hsa-miR-877-5p 0.0373466503922957 233 48 5 0.104166666666667 0.0214592274678112
MIRNA MIRNA:hsa-miR-4735-5p hsa-miR-4735-5p 0.037795484745056 179 37 4 0.108108108108108 0.0223463687150838
MIRNA MIRNA:hsa-miR-3129-3p hsa-miR-3129-3p 0.037795484745056 55 54 3 0.0555555555555556 0.0545454545454545
MIRNA MIRNA:hsa-miR-4672 hsa-miR-4672 0.037795484745056 131 50 4 0.08 0.0305343511450382
MIRNA MIRNA:hsa-miR-5583-5p hsa-miR-5583-5p 0.037795484745056 56 54 3 0.0555555555555556 0.0535714285714286
MIRNA MIRNA:hsa-miR-548as-3p hsa-miR-548as-3p 0.037795484745056 171 18 3 0.166666666666667 0.0175438596491228
REAC REAC:R-HSA-5696398 Nucleotide Excision Repair 0.000363051766576294 109 4 3 0.75 0.0275229357798165
REAC REAC:R-HSA-73894 DNA Repair 0.00279032696013831 303 4 3 0.75 0.0099009900990099
REAC REAC:R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 0.00563438511352496 35 37 3 0.0810810810810811 0.0857142857142857
REAC REAC:R-HSA-400253 Circadian Clock 0.019149417468145 67 34 3 0.0882352941176471 0.0447761194029851
REAC REAC:R-HSA-195258 RHO GTPase Effectors 0.0349891925588643 283 37 5 0.135135135135135 0.0176678445229682
REAC REAC:R-HSA-199991 Membrane Trafficking 0.0492519128975244 625 46 8 0.173913043478261 0.0128
TF TF:M08451_1 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA; match class: 1 7.96717409599335e-06 2584 60 27 0.45 0.0104489164086687
TF TF:M08231_1 Factor: Elk-1:T-bet; motif: TCACACCGGAAGNN; match class: 1 0.000524791158849275 1581 45 16 0.355555555555556 0.0101201771030993
TF TF:M03970 Factor: ELK1; motif: ACCGGAAGTN 0.000886795649231822 4782 59 32 0.542372881355932 0.00669176076955249
TF TF:M03791 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY 0.000886795649231822 2969 61 25 0.409836065573771 0.00842034355001684
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.000886795649231822 7045 61 41 0.672131147540984 0.00581973030518098
TF TF:M08213_1 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN; match class: 1 0.000886795649231822 1417 55 16 0.290909090909091 0.0112914608327452
TF TF:M03983 Factor: ETV5; motif: NCCGGAWGYN 0.000889382352005651 3129 59 25 0.423728813559322 0.00798977309044423
TF TF:M08451 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA 0.000903198023159051 8421 60 44 0.733333333333333 0.0052250326564541
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.000903198023159051 8219 61 44 0.721311475409836 0.00535344932473537
TF TF:M08213 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN 0.00117298827746622 6273 57 35 0.614035087719298 0.00557946755938148
TF TF:M03981 Factor: ETV3; motif: ACCGGAAGTN 0.00117298827746622 2327 40 16 0.4 0.00687580575848732
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.00117298827746622 8056 61 43 0.704918032786885 0.00533763654419067
TF TF:M02062_1 Factor: Erg; motif: ACCGGAAGTN; match class: 1 0.00117298827746622 2718 61 23 0.377049180327869 0.00846210448859456
TF TF:M09608_1 Factor: Erg; motif: NNACCGGAARTSN; match class: 1 0.00117298827746622 2389 61 21 0.344262295081967 0.00879028882377564
TF TF:M11415 Factor: GABP-alpha; motif: NRCCGGAAGTN 0.00117298827746622 3257 61 25 0.409836065573771 0.00767577525330058
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.00117298827746622 12747 61 55 0.901639344262295 0.00431474072330745
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.00117298827746622 4592 61 31 0.508196721311475 0.00675087108013937
TF TF:M01876 Factor: GABP-beta; motif: ASMGGAAGKGN 0.00117298827746622 2138 56 19 0.339285714285714 0.00888681010289991
TF TF:M09935 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN 0.00117298827746622 4420 61 30 0.491803278688525 0.00678733031674208
TF TF:M02055_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.00117298827746622 2176 51 18 0.352941176470588 0.00827205882352941
TF TF:M01163 Factor: Elk-1; motif: AACCGGAAGTR 0.00117298827746622 5260 56 31 0.553571428571429 0.005893536121673
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.00117298827746622 9423 61 47 0.770491803278688 0.00498779581874138
TF TF:M01214_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.00117298827746622 2176 51 18 0.352941176470588 0.00827205882352941
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.00117298827746622 4677 61 31 0.508196721311475 0.00662818045755826
TF TF:M11422 Factor: Erm; motif: NRCMGGAAGTN 0.00117298827746622 4669 61 31 0.508196721311475 0.00663953737417006
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.0012413158581269 3759 61 27 0.442622950819672 0.00718276137270551
TF TF:M03970_1 Factor: ELK1; motif: ACCGGAAGTN; match class: 1 0.0012413158581269 1097 39 11 0.282051282051282 0.0100273473108478
TF TF:M11432 Factor: Elk-1; motif: NACMGGAAGTN 0.0012413158581269 6140 61 36 0.590163934426229 0.00586319218241042
TF TF:M02068 Factor: etv3; motif: ACCGGAAGYN 0.00128278573444161 3443 59 25 0.423728813559322 0.00726110949753122
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.00131893690860769 8318 61 43 0.704918032786885 0.0051695119018995
TF TF:M04714_1 Factor: Elf-1; motif: ACTTCCGGG; match class: 1 0.00131893690860769 2659 61 22 0.360655737704918 0.00827378713802181
TF TF:M03982 Factor: ETV4; motif: ACCGGAAGTN 0.00159412581675336 6826 61 38 0.622950819672131 0.00556694989745092
TF TF:M09606 Factor: nerf; motif: NRRNSCGGAAGNRNNNN 0.00159412581675336 6249 61 36 0.590163934426229 0.0057609217474796
TF TF:M11427_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00159412581675336 4606 61 30 0.491803278688525 0.00651324359531046
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00174406748494958 4902 61 31 0.508196721311475 0.00632394940840473
TF TF:M04714 Factor: Elf-1; motif: ACTTCCGGG 0.00174406748494958 7798 61 41 0.672131147540984 0.00525775839958964
TF TF:M11433_1 Factor: Elk-1; motif: NRCCGGAAGTN; match class: 1 0.00192914447257372 2261 39 15 0.384615384615385 0.00663423264042459
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.00195159425894943 4963 45 25 0.555555555555556 0.00503727584122507
TF TF:M01752_1 Factor: ERG; motif: ACCGGAART; match class: 1 0.00207478183997038 3705 61 26 0.426229508196721 0.00701754385964912
TF TF:M09892 Factor: E2F-1; motif: NNNNGGCGGGAARN 0.00207478183997038 13528 61 56 0.918032786885246 0.00413956238911887
TF TF:M11218_1 Factor: CREB1; motif: NRTGAYGCGTN; match class: 1 0.00207478183997038 2438 59 20 0.338983050847458 0.00820344544708778
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.0020790363855522 2702 50 19 0.38 0.00703182827535159
TF TF:M08231 Factor: Elk-1:T-bet; motif: TCACACCGGAAGNN 0.0020790363855522 6635 57 35 0.614035087719298 0.0052750565184627
TF TF:M03990 Factor: GABPA; motif: ACCGGAAGTN 0.0020790363855522 5258 61 32 0.524590163934426 0.00608596424496006
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.00213476499104267 7600 61 40 0.655737704918033 0.00526315789473684
TF TF:M11447_1 Factor: Elf-1; motif: NAMCCGGAAGTN; match class: 1 0.00219834042472457 2593 61 21 0.344262295081967 0.00809872734284612
TF TF:M00074 Factor: c-Ets-1(p54); motif: NNACMGGAWRTNN 0.0022378391762457 3484 44 20 0.454545454545455 0.00574052812858783
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.00226471980439355 8273 61 42 0.688524590163934 0.00507675571135018
TF TF:M11382 Factor: ESE-1; motif: NWTRCGGAWGCN 0.00226471980439355 10339 61 48 0.786885245901639 0.00464261533997485
TF TF:M02073 Factor: Fli-1; motif: ACCGGAAGYN 0.00234550296535823 5839 59 33 0.559322033898305 0.00565165268025347
TF TF:M11455 Factor: ELFR; motif: NANSCGGAAGTN 0.00234550296535823 631 49 9 0.183673469387755 0.0142630744849445
TF TF:M01258 Factor: GABP; motif: CACTTCCGGNNN 0.00234550296535823 2838 61 22 0.360655737704918 0.00775193798449612
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.00234550296535823 4639 57 28 0.491228070175439 0.00603578357404613
TF TF:M09901 Factor: nerf; motif: NNNCCGGAAGTGN 0.00241300631437052 5352 61 32 0.524590163934426 0.00597907324364723
TF TF:M03982_1 Factor: ETV4; motif: ACCGGAAGTN; match class: 1 0.00241300631437052 2009 61 18 0.295081967213115 0.00895968143354903
TF TF:M11420 Factor: ER81; motif: NACCGGAAGTN 0.00241300631437052 3210 59 23 0.389830508474576 0.00716510903426791
TF TF:M02061 Factor: ERF; motif: ACCGGAARYN 0.00250891044315491 2579 58 20 0.344827586206897 0.00775494377665762
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.00257513204973302 8690 61 43 0.704918032786885 0.0049482163406214
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.0029430361363444 8743 61 43 0.704918032786885 0.00491822029051813
TF TF:M03971_1 Factor: ELK1; motif: NACTTCCGSCGGAAGYN; match class: 1 0.0029430361363444 7157 61 38 0.622950819672131 0.00530948721531368
TF TF:M08759_1 Factor: c-Ets-2; motif: NCCGGAAGTG; match class: 1 0.0029430361363444 2915 61 22 0.360655737704918 0.00754716981132075
TF TF:M11428 Factor: PEA3; motif: NACCGGAAGTN 0.00297810311256043 7186 61 38 0.622950819672131 0.00528806011689396
TF TF:M02066_1 Factor: PEA3; motif: RCCGGAAGYN; match class: 1 0.00297810311256043 2283 61 19 0.311475409836066 0.00832238282961016
TF TF:M09905_1 Factor: SAP-1; motif: NNCCGGAAGTGN; match class: 1 0.00297810311256043 2989 52 20 0.384615384615385 0.00669120107059217
TF TF:M08952_1 Factor: NF-KAPPAB1; motif: NGGKRNTTYCCCN; match class: 1 0.00297810311256043 3457 8 7 0.875 0.00202487706103558
TF TF:M12273 Factor: YY1; motif: GGCSGCCATTTTGN 0.00297810311256043 6229 48 29 0.604166666666667 0.00465564296034677
TF TF:M11451 Factor: Elf-1; motif: NANCCGGAAGTN 0.00297810311256043 6886 61 37 0.60655737704918 0.0053732210281731
TF TF:M02071_1 Factor: ETV7; motif: NCCGGAANNN; match class: 1 0.00297810311256043 4465 57 27 0.473684210526316 0.00604703247480403
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.00297810311256043 5332 57 30 0.526315789473684 0.00562640660165041
TF TF:M03988_1 Factor: FLI1; motif: ACCGGAARTN; match class: 1 0.0030678130118648 2950 61 22 0.360655737704918 0.00745762711864407
TF TF:M11424 Factor: Erm; motif: NNSCGGAWGYN 0.0030678130118648 8149 61 41 0.672131147540984 0.00503129218308995
TF TF:M02067_1 Factor: ER71; motif: ACCGGAARYN; match class: 1 0.00308085358135029 1619 57 15 0.263157894736842 0.00926497838171711
TF TF:M11436 Factor: SAP-1; motif: NRNCGGAWRYN 0.00317642676558219 1431 50 13 0.26 0.00908455625436757
TF TF:M12275 Factor: YY1; motif: NGCCGCCATYTTGN 0.00326592007605536 7043 48 31 0.645833333333333 0.00440153343745563
TF TF:M01035 Factor: YY1; motif: NYNKCCATNTT 0.00326592007605536 5924 48 28 0.583333333333333 0.00472653612424038
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.00326592007605536 10585 61 48 0.786885245901639 0.00453471894189891
TF TF:M12273_1 Factor: YY1; motif: GGCSGCCATTTTGN; match class: 1 0.00344366818249818 1261 42 11 0.261904761904762 0.00872323552735924
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.00344366818249818 4201 61 27 0.442622950819672 0.00642704118067127
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.00344366818249818 3233 57 22 0.385964912280702 0.00680482523971543
TF TF:M03985_1 Factor: ETV6; motif: NSCGGAAGTR; match class: 1 0.00381643913478326 105 39 4 0.102564102564103 0.0380952380952381
TF TF:M11414 Factor: GABP-alpha; motif: NACCGGAAGTN 0.00396453262662414 2907 59 21 0.355932203389831 0.00722394220846233
TF TF:M08757 Factor: nerf; motif: AAMCCGGAAGTN 0.00396453262662414 715 49 9 0.183673469387755 0.0125874125874126
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.00400985066472917 5133 60 30 0.5 0.00584453535943892
TF TF:M11454 Factor: ELFR; motif: NANGMGGAAGTN 0.00412361114169422 1072 50 11 0.22 0.0102611940298507
TF TF:M11432_1 Factor: Elk-1; motif: NACMGGAAGTN; match class: 1 0.00414946498483671 1525 49 13 0.26530612244898 0.00852459016393443
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.00414946498483671 6749 61 36 0.590163934426229 0.00533412357386279
TF TF:M01167 Factor: SAP-1a; motif: NACCGGAAGTV 0.00415906791729554 1948 56 16 0.285714285714286 0.0082135523613963
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.00415906791729554 8322 61 41 0.672131147540984 0.0049267003124249
TF TF:M11457 Factor: nerf; motif: NANGCGGAAGTR 0.00415906791729554 1082 50 11 0.22 0.0101663585951941
TF TF:M11433 Factor: Elk-1; motif: NRCCGGAAGTN 0.00415906791729554 7679 61 39 0.639344262295082 0.00507878630029952
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.00415906791729554 4024 61 26 0.426229508196721 0.00646123260437376
TF TF:M04698 Factor: GABP-alpha; motif: CACTTCCGG 0.00415906791729554 3196 51 20 0.392156862745098 0.00625782227784731
TF TF:M11419_1 Factor: ER81; motif: NNCCGGAWGYN; match class: 1 0.00415906791729554 1427 39 11 0.282051282051282 0.00770847932725999
TF TF:M11384 Factor: ESE-1; motif: ACCCGGAAGTRNNNNNNNWWWWW 0.00415906791729554 3272 50 20 0.4 0.00611246943765281
TF TF:M02063_1 Factor: c-ets-1; motif: ACCGGAWGTN; match class: 1 0.00418391825173939 2396 61 19 0.311475409836066 0.00792988313856427
TF TF:M11447 Factor: Elf-1; motif: NAMCCGGAAGTN 0.00419410460832398 7703 61 39 0.639344262295082 0.00506296248214981
TF TF:M11460 Factor: nerf; motif: NANSCGGAAGTN 0.00419410460832398 736 49 9 0.183673469387755 0.0122282608695652
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.00419410460832398 11116 61 49 0.80327868852459 0.0044080604534005
TF TF:M04696_1 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN; match class: 1 0.00460118503195205 1973 56 16 0.285714285714286 0.00810947795235682
TF TF:M11425 Factor: PEA3; motif: NACCGGAAGTN 0.00460658836305514 7428 61 38 0.622950819672131 0.00511577813677975
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.00502580343328088 4607 61 28 0.459016393442623 0.00607770783590189
TF TF:M11419 Factor: ER81; motif: NNCCGGAWGYN 0.00509978461865485 5699 61 32 0.524590163934426 0.00561502017897877
TF TF:M11425_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00538284927960557 2330 59 18 0.305084745762712 0.00772532188841202
TF TF:M11451_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.00538284927960557 2112 59 17 0.288135593220339 0.00804924242424242
TF TF:M04710 Factor: CHD2; motif: TCTCGCGAG 0.00538284927960557 14109 61 56 0.918032786885246 0.00396909773903182
TF TF:M03974 Factor: ERF; motif: ACCGGAAGTR 0.00538284927960557 956 40 9 0.225 0.00941422594142259
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.00542354131695868 6892 61 36 0.590163934426229 0.00522344747533372
TF TF:M11430 Factor: PEA3; motif: NACCGGAAGTN 0.00546136665534448 10865 61 48 0.786885245901639 0.00441785549930971
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.0055569410263356 10512 61 47 0.770491803278688 0.00447108066971081
TF TF:M03966 Factor: ELF1; motif: AACCCGGAAGTR 0.0055569410263356 6610 61 35 0.573770491803279 0.00529500756429652
TF TF:M05439_1 Factor: RREB-1; motif: GGGWCSA; match class: 1 0.00565632301443242 3200 5 5 1 0.0015625
TF TF:M11404_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.00582043065255182 3171 57 21 0.368421052631579 0.00662251655629139
TF TF:M10098 Factor: DP-1; motif: NRNNGGCGGGAANN 0.00586942707143031 7015 52 32 0.615384615384615 0.00456165359942979
TF TF:M02074_1 Factor: GABPalpha; motif: RCCGGAWRYN; match class: 1 0.00586942707143031 1005 39 9 0.230769230769231 0.00895522388059702
TF TF:M00793 Factor: YY1; motif: GCCATNTTN 0.00593808444502918 5186 48 25 0.520833333333333 0.00482067103740841
TF TF:M09605 Factor: Elf-1; motif: NAANCMGGAAGTGN 0.00593808444502918 5778 61 32 0.524590163934426 0.00553824852890273
TF TF:M09789 Factor: TFDP1; motif: NSGCGGGAANN 0.00600986380300453 2026 51 15 0.294117647058824 0.00740375123395854
TF TF:M08523_1 Factor: E2F-1:TBR2; motif: NGGTGNNANGGCGCNNTNNCRNNN; match class: 1 0.00634469541347358 7423 60 37 0.616666666666667 0.00498450761147784
TF TF:M02090_1 Factor: E2F-4; motif: GCGGGAAANA; match class: 1 0.00634469541347358 6378 61 34 0.557377049180328 0.00533082470994042
TF TF:M02060 Factor: Net; motif: ACCGGAARTN 0.00644001712408335 574 40 7 0.175 0.0121951219512195
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.00682784509332939 11728 61 50 0.819672131147541 0.00426330150068213
TF TF:M10948_1 Factor: rax; motif: NNCRTTAN; match class: 1 0.00727327765571543 5245 43 23 0.534883720930233 0.00438512869399428
TF TF:M02044_1 Factor: YY1; motif: GCCGCCATTTTG; match class: 1 0.00727327765571543 1198 42 10 0.238095238095238 0.00834724540901502
TF TF:M09935_1 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN; match class: 1 0.00727327765571543 1047 39 9 0.230769230769231 0.00859598853868195
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.00727327765571543 12550 61 52 0.852459016393443 0.00414342629482072
TF TF:M11400 Factor: Fli-1; motif: NACCGGAARTN 0.00737843621579518 9946 61 45 0.737704918032787 0.00452443193243515
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.0074167757773374 15260 61 58 0.950819672131147 0.00380078636959371
TF TF:M11603 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.00771969109942473 16361 60 59 0.983333333333333 0.00360613654422101
TF TF:M11438 Factor: SAP-1; motif: NTCGTAAATGCN 0.00789584687396093 5901 44 25 0.568181818181818 0.00423657007286901
TF TF:M11005_1 Factor: LHX4; motif: NNCRTTAN; match class: 1 0.00790612049748479 4203 49 22 0.448979591836735 0.00523435641208661
TF TF:M08759 Factor: c-Ets-2; motif: NCCGGAAGTG 0.00803328520237524 8319 61 40 0.655737704918033 0.00480827022478663
TF TF:M08423 Factor: TEF-3:ER81; motif: ACCGGAAATRCC 0.00803328520237524 3845 53 22 0.415094339622642 0.00572171651495449
TF TF:M11428_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0083008896119837 2146 45 14 0.311111111111111 0.0065237651444548
TF TF:M07234 Factor: YY1; motif: CAARATGGCNGC 0.0083008896119837 6045 48 27 0.5625 0.00446650124069479
TF TF:M08913_1 Factor: FLI-1; motif: NAYTTCCGGT; match class: 1 0.00833044644610588 3055 61 21 0.344262295081967 0.00687397708674304
TF TF:M11424_1 Factor: Erm; motif: NNSCGGAWGYN; match class: 1 0.0083435684515729 2835 52 18 0.346153846153846 0.00634920634920635
TF TF:M02067 Factor: ER71; motif: ACCGGAARYN 0.00839603476106913 5930 61 32 0.524590163934426 0.00539629005059022
TF TF:M04710_1 Factor: CHD2; motif: TCTCGCGAG; match class: 1 0.00857685451995299 11477 61 49 0.80327868852459 0.00426940838198135
TF TF:M11446 Factor: Elf-1; motif: RANSMGGAAGTR 0.00881534661227475 2915 51 18 0.352941176470588 0.00617495711835334
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.00901866807295876 10765 61 47 0.770491803278688 0.00436600092893637
TF TF:M11402 Factor: Fli-1; motif: NACCGGAARTN 0.00978432606836391 3885 50 21 0.42 0.00540540540540541
TF TF:M09913 Factor: ER81; motif: NNCCGGAAGYG 0.00989579332202305 2871 61 20 0.327868852459016 0.00696621386276559
TF TF:M02073_1 Factor: Fli-1; motif: ACCGGAAGYN; match class: 1 0.00989579332202305 1488 57 13 0.228070175438596 0.00873655913978495
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00995585813993189 11053 60 47 0.783333333333333 0.00425223921107392
TF TF:M02056_1 Factor: ELF4; motif: NCCGGAARTN; match class: 1 0.00998659085979783 1291 57 12 0.210526315789474 0.00929512006196747
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.00998659085979783 10107 61 45 0.737704918032787 0.00445235975066785
TF TF:M11440 Factor: Net; motif: NRCCGGAAGTN 0.00998659085979783 449 40 6 0.15 0.0133630289532294
TF TF:M03823_1 Factor: FOXO1A; motif: AAACAA; match class: 1 0.0100556442240727 9098 61 42 0.688524590163934 0.00461639920861728
TF TF:M03854_1 Factor: SRY; motif: TTGTTT; match class: 1 0.0100556442240727 9098 61 42 0.688524590163934 0.00461639920861728
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.0100556442240727 10116 61 45 0.737704918032787 0.00444839857651246
TF TF:M09608 Factor: Erg; motif: NNACCGGAARTSN 0.0100556442240727 8152 57 37 0.649122807017544 0.0045387634936212
TF TF:M07141 Factor: FPM315; motif: GGAGGAGGRRGRGGRGGRRGR 0.0101285533113867 2175 7 5 0.714285714285714 0.00229885057471264
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.0101900603702047 10837 61 47 0.770491803278688 0.00433699363292424
TF TF:M00740_1 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC; match class: 1 0.010191546872962 4583 27 15 0.555555555555556 0.00327296530656775
TF TF:M07370 Factor: YY1; motif: NNNNAARATGGNNNN 0.0103458109593307 5811 48 26 0.541666666666667 0.00447427293064877
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.0103458109593307 5745 61 31 0.508196721311475 0.00539599651871192
TF TF:M09904 Factor: Elk-1; motif: RCCGGAAGTGN 0.0108561856524029 8164 61 39 0.639344262295082 0.00477707006369427
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.0108561856524029 9474 61 43 0.704918032786885 0.00453873759763563
TF TF:M11434_1 Factor: Elk-1; motif: NRSCGGAAGNN; match class: 1 0.0109941412212467 2935 52 18 0.346153846153846 0.00613287904599659
TF TF:M11437 Factor: SAP-1; motif: NRCCGGAWGYN 0.0109941412212467 2788 50 17 0.34 0.00609756097560976
TF TF:M11375_1 Factor: Spi-B; motif: NAWGCGGAAGTN; match class: 1 0.0115431583531375 234 51 5 0.0980392156862745 0.0213675213675214
TF TF:M01592 Factor: LBP9; motif: CCRGNNNNARCCRGYYN 0.0116266877885792 1422 26 8 0.307692307692308 0.00562587904360056
TF TF:M09605_1 Factor: Elf-1; motif: NAANCMGGAAGTGN; match class: 1 0.0116266877885792 1306 50 11 0.22 0.00842266462480858
TF TF:M11439 Factor: Net; motif: NRCCGGAAGTN 0.0116266877885792 2568 59 18 0.305084745762712 0.00700934579439252
TF TF:M04953_1 Factor: Sp1; motif: GGNDGGRGGCGGGG; match class: 1 0.0122630362004491 4065 5 5 1 0.001230012300123
TF TF:M09895 Factor: E2F-6; motif: NGGGCGGGARRNN 0.0123097431899847 7765 52 33 0.634615384615385 0.0042498390212492
TF TF:M08233 Factor: ERF:C/EBPdelta; motif: NNCGGAWRTTGCGCAAY 0.0124773964182597 5782 23 15 0.652173913043478 0.00259425804219993
TF TF:M02116 Factor: Sox-10; motif: NACAAWG 0.0124773964182597 14212 24 24 1 0.00168871376301717
TF TF:M00245 Factor: Egr-3; motif: NTGCGTGGGCGK 0.0129876376339106 7313 61 36 0.590163934426229 0.00492274032544783
TF TF:M05439 Factor: RREB-1; motif: GGGWCSA 0.013084960980781 8635 57 38 0.666666666666667 0.00440069484655472
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.0132289364593624 13184 60 52 0.866666666666667 0.00394417475728155
TF TF:M09901_1 Factor: nerf; motif: NNNCCGGAAGTGN; match class: 1 0.0138194653075822 1363 57 12 0.210526315789474 0.00880410858400587
TF TF:M00032_1 Factor: c-Ets-1(p54); motif: NCMGGAWGYN; match class: 1 0.0142380748748844 2161 59 16 0.271186440677966 0.00740397963905599
TF TF:M03973 Factor: ELK4; motif: ACCGGAARTN 0.014373827217951 700 40 7 0.175 0.01
TF TF:M03990_1 Factor: GABPA; motif: ACCGGAAGTN; match class: 1 0.014373827217951 1206 39 9 0.230769230769231 0.00746268656716418
TF TF:M08246 Factor: ER71:C/EBPdelta; motif: NNCGGAWRTTRCGYAAN 0.014373827217951 8387 42 29 0.69047619047619 0.00345773220460236
TF TF:M11450 Factor: Elf-1; motif: NANSCGGAAGTR 0.0144148235405968 5601 61 30 0.491803278688525 0.00535618639528656
TF TF:M03812 Factor: arnt; motif: CACGYA 0.0145126304056729 4330 60 25 0.416666666666667 0.00577367205542725
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.016086580794002 10002 61 44 0.721311475409836 0.00439912017596481
TF TF:M00325 Factor: NRSE; motif: TTYAGCWCCDCGGASAGYRCC 0.0161322910930904 1578 6 4 0.666666666666667 0.00253485424588086
TF TF:M09607_1 Factor: SAP-1; motif: ACCGGAAGTNN; match class: 1 0.0164419596351565 977 39 8 0.205128205128205 0.00818833162743091
TF TF:M00491_1 Factor: MAZR; motif: NSGGGGGGGGMCN; match class: 1 0.016500589056681 368 21 4 0.19047619047619 0.0108695652173913
TF TF:M11413 Factor: ER71; motif: NACCGGAARTN 0.0166047327847777 2111 50 14 0.28 0.00663192799621033
TF TF:M12277 Factor: YY2; motif: NKCSGCCATTTTGN 0.0170418271205977 135 56 4 0.0714285714285714 0.0296296296296296
TF TF:M00737 Factor: E2F-1:DP-2; motif: TTTSSCGC 0.0170418271205977 8771 48 33 0.6875 0.00376239881427431
TF TF:M03972 Factor: ELK3; motif: ACCGGAAGTN 0.0170418271205977 1211 40 9 0.225 0.0074318744838976
TF TF:M08800 Factor: ARNT; motif: YRCGTGNN 0.0173263976344751 914 42 8 0.19047619047619 0.0087527352297593
TF TF:M11270_1 Factor: JunD; motif: NRTGACGTCATS; match class: 1 0.0174933382293217 4298 30 15 0.5 0.00348999534667287
TF TF:M11375 Factor: Spi-B; motif: NAWGCGGAAGTN 0.0176165033071205 2608 51 16 0.313725490196078 0.00613496932515337
TF TF:M10104 Factor: YY1; motif: CAARATGGCGGC 0.0178155973319191 6071 48 26 0.541666666666667 0.00428265524625268
TF TF:M01165 Factor: Elk-1; motif: RACCGGAAGTR 0.0178172873861635 7773 61 37 0.60655737704918 0.00476006689823749
TF TF:M08760 Factor: ETV7; motif: NNSCGGAAGTR 0.017865446337171 2349 51 15 0.294117647058824 0.00638569604086846
TF TF:M11415_1 Factor: GABP-alpha; motif: NRCCGGAAGTN; match class: 1 0.0183699041058011 546 39 6 0.153846153846154 0.010989010989011
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.0184807870476012 10430 61 45 0.737704918032787 0.00431447746883989
TF TF:M09723_1 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS; match class: 1 0.0184807870476012 6113 60 31 0.516666666666667 0.00507115982332734
TF TF:M01471 Factor: Lhx3; motif: NNAATTAATTAAWWNNN 0.0186300138495306 981 40 8 0.2 0.00815494393476045
TF TF:M01118_1 Factor: WT1; motif: SMCNCCNSC; match class: 1 0.0186490832997036 2766 58 18 0.310344827586207 0.00650759219088937
TF TF:M02044 Factor: YY1; motif: GCCGCCATTTTG 0.0186490832997036 6102 48 26 0.541666666666667 0.0042608980662078
TF TF:M01597 Factor: Zfp281; motif: TGGGGGAGGGG 0.0186490832997036 1016 58 10 0.172413793103448 0.00984251968503937
TF TF:M11418 Factor: ER81; motif: NRCMGGAWGNN 0.0186490832997036 3978 59 23 0.389830508474576 0.00578179989944696
TF TF:M04950 Factor: Egr-1; motif: NGCGTGCGY 0.0188448925209009 10935 28 24 0.857142857142857 0.00219478737997257
TF TF:M02061_1 Factor: ERF; motif: ACCGGAARYN; match class: 1 0.0188448925209009 363 39 5 0.128205128205128 0.0137741046831956
TF TF:M03969 Factor: ELF5; motif: ANSMGGAAGTN 0.0188448925209009 3339 61 21 0.344262295081967 0.00628930817610063
TF TF:M07415_1 Factor: Elf-1; motif: AWCCCGGAAGTN; match class: 1 0.0188881745003863 2397 61 17 0.278688524590164 0.00709219858156028
TF TF:M11379 Factor: ESE-1; motif: ACCCGGAAGTRNNNNNNNNWWWW 0.0188881745003863 3200 51 18 0.352941176470588 0.005625
TF TF:M02069_1 Factor: Erm; motif: ACCGGAAGTN; match class: 1 0.0188881745003863 1955 61 15 0.245901639344262 0.00767263427109974
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.0194922997695233 6033 61 31 0.508196721311475 0.00513840543676446
TF TF:M09607 Factor: SAP-1; motif: ACCGGAAGTNN 0.0194922997695233 4727 51 23 0.450980392156863 0.00486566532684578
TF TF:M11228_1 Factor: ATF-6; motif: GRTGACGTCAYC; match class: 1 0.0194922997695233 2102 30 10 0.333333333333333 0.00475737392959087
TF TF:M11078_1 Factor: TCFL5; motif: KCACGCGCNC; match class: 1 0.0199181126579664 172 21 3 0.142857142857143 0.0174418604651163
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.0204404198703807 7544 61 36 0.590163934426229 0.00477200424178155
TF TF:M11228 Factor: ATF-6; motif: GRTGACGTCAYC 0.0204617221397939 2123 30 10 0.333333333333333 0.00471031559114461
TF TF:M02086 Factor: Cdx-1; motif: TTTATK 0.0204617221397939 14414 56 51 0.910714285714286 0.00353822672401832
TF TF:M00447 Factor: AR; motif: AGWACATNWTGTTCT 0.0204617221397939 4183 57 23 0.403508771929825 0.00549844609132202
TF TF:M11849 Factor: MR; motif: NGNACRNNNYGTNCN 0.0207920972325996 4324 49 21 0.428571428571429 0.00485661424606846
TF TF:M11407 Factor: Pet-1; motif: NACCGGAAGTN 0.0207920972325996 772 40 7 0.175 0.00906735751295337
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.021198536374089 10488 58 43 0.741379310344828 0.00409992372234935
TF TF:M07611 Factor: p54NRB; motif: GRNNNMGGATGRMNNCGGA 0.021198536374089 6991 21 15 0.714285714285714 0.00214561579173223
TF TF:M04698_1 Factor: GABP-alpha; motif: CACTTCCGG; match class: 1 0.0215133569816123 576 39 6 0.153846153846154 0.0104166666666667
TF TF:M11498_1 Factor: OC-2; motif: NNATCGATYN; match class: 1 0.0216228714930682 396 56 6 0.107142857142857 0.0151515151515152
TF TF:M12186_1 Factor: BTEB4; motif: NCCACGCCCM; match class: 1 0.0216228714930682 3958 10 7 0.7 0.00176856998484083
TF TF:M04690 Factor: C/EBPbeta; motif: RTTGCGCAA 0.0221246739757309 3915 24 12 0.5 0.00306513409961686
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.0227274113576751 7600 61 36 0.590163934426229 0.00473684210526316
TF TF:M11877_1 Factor: pax-2; motif: NCGTCACGCNYSRNYGCNYN; match class: 1 0.0230292356094233 5304 55 26 0.472727272727273 0.00490196078431373
TF TF:M09971 Factor: GKLF; motif: WGGGYGKGGC 0.0230783437729856 5546 30 17 0.566666666666667 0.00306527226830148
TF TF:M03967 Factor: ELF3; motif: WACCCGGAAGTAN 0.0230783437729856 7610 61 36 0.590163934426229 0.00473061760840999
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.0231488660363457 14429 61 55 0.901639344262295 0.0038117679672881
TF TF:M09972 Factor: BTEB2; motif: WGGGTGKGGCNGGN 0.0234805738364144 9217 61 41 0.672131147540984 0.00444830205055875
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.0239442731749833 10939 61 46 0.754098360655738 0.00420513758113173
TF TF:M11601 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0243346400279653 14823 60 55 0.916666666666667 0.00371044997638805
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.0250256438752139 10262 61 44 0.721311475409836 0.00428766322354317
TF TF:M03987 Factor: FEV; motif: ACCGGAAGTN 0.0250256438752139 1318 40 9 0.225 0.00682852807283763
TF TF:M00130 Factor: FOXD3; motif: NAWTGTTTRTTT 0.0250256438752139 4211 51 21 0.411764705882353 0.00498693896936595
TF TF:M11446_1 Factor: Elf-1; motif: RANSMGGAAGTR; match class: 1 0.0250692270105385 309 50 5 0.1 0.0161812297734628
TF TF:M07380_1 Factor: E2F-4; motif: NTTTCSCGCC; match class: 1 0.0250692270105385 7965 61 37 0.60655737704918 0.00464532328939109
TF TF:M03899 Factor: EGR4; motif: NNMCGCCCACGCANNN 0.0251741977888209 2037 61 15 0.245901639344262 0.00736377025036819
TF TF:M08225_1 Factor: Elk-1:Pax-5; motif: ACCGGAACYACGCWTSANYG; match class: 1 0.02635810649438 7993 32 22 0.6875 0.00275240835731265
TF TF:M10990 Factor: lmx1b; motif: NNNNTAATTAN 0.0264122698876901 1336 56 11 0.196428571428571 0.00823353293413174
TF TF:M10914 Factor: pitx1; motif: NTAATCCN 0.0267436630804306 182 23 3 0.130434782608696 0.0164835164835165
TF TF:M08206_1 Factor: E2F-3:Prrxl1; motif: SGCGCTAATTNN; match class: 1 0.0267436630804306 5052 61 27 0.442622950819672 0.00534441805225653
TF TF:M10900 Factor: Otx1; motif: NTAATCCN 0.0267436630804306 182 23 3 0.130434782608696 0.0164835164835165
TF TF:M02068_1 Factor: etv3; motif: ACCGGAAGYN; match class: 1 0.0267436630804306 613 39 6 0.153846153846154 0.00978792822185971
TF TF:M09904_1 Factor: Elk-1; motif: RCCGGAAGTGN; match class: 1 0.0267990495209317 2743 61 18 0.295081967213115 0.00656215822092599
TF TF:M01118 Factor: WT1; motif: SMCNCCNSC 0.0273567335436708 6808 18 13 0.722222222222222 0.00190951821386604
TF TF:M04744_1 Factor: ATF-3; motif: GGCGCSSNSNGRTSACGTSA; match class: 1 0.027698129807698 4889 54 24 0.444444444444444 0.00490897934137861
TF TF:M08223_1 Factor: Elk-1:OC-2; motif: RCCGGAASCGATCGATNN; match class: 1 0.0277967031323021 5853 59 29 0.491525423728814 0.00495472407312489
TF TF:M00491 Factor: MAZR; motif: NSGGGGGGGGMCN 0.0277967031323021 1207 21 6 0.285714285714286 0.00497100248550124
TF TF:M00084 Factor: MZF-1; motif: KNGNKAGGGGNAA 0.0288720681748293 6543 6 6 1 0.000917010545621275
TF TF:M02058 Factor: SAP1A; motif: NCCGGAARYN 0.0288720681748293 842 40 7 0.175 0.00831353919239905
TF TF:M10098_1 Factor: DP-1; motif: NRNNGGCGGGAANN; match class: 1 0.0288720681748293 2168 9 5 0.555555555555556 0.00230627306273063
TF TF:M04744 Factor: ATF-3; motif: GGCGCSSNSNGRTSACGTSA 0.0288720681748293 10089 59 42 0.711864406779661 0.00416294974724948
TF TF:M00074_1 Factor: c-Ets-1(p54); motif: NNACMGGAWRTNN; match class: 1 0.0288720681748293 421 39 5 0.128205128205128 0.0118764845605701
TF TF:M11452_1 Factor: Elf-1; motif: NANGCGGAAGTR; match class: 1 0.0288720681748293 1696 39 10 0.256410256410256 0.00589622641509434
TF TF:M12231 Factor: LRF; motif: NCGACCACCGN 0.0288720681748293 11477 25 22 0.88 0.00191687723272632
TF TF:M00024_1 Factor: E2F-1; motif: TWSGCGCGAAAAYKR; match class: 1 0.0288720681748293 2681 58 17 0.293103448275862 0.00634091756807161
TF TF:M08232_1 Factor: Elk-1:TEF; motif: RCCGGAAGTTACGTAAN; match class: 1 0.0288720681748293 1294 42 9 0.214285714285714 0.00695517774343122
TF TF:M00430_1 Factor: E2F-1; motif: NTTSGCGG; match class: 1 0.0288720681748293 2524 23 9 0.391304347826087 0.00356576862123613
TF TF:M08220 Factor: Elk-1:HOXA3; motif: ACCGGWAATKRNNTNWCNNATTAN 0.0288720681748293 12140 61 49 0.80327868852459 0.00403624382207578
TF TF:M00360_1 Factor: Pax-3; motif: TCGTCACRCTTHM; match class: 1 0.0290459578990312 5491 31 17 0.548387096774194 0.00309597523219814
TF TF:M08220_1 Factor: Elk-1:HOXA3; motif: ACCGGWAATKRNNTNWCNNATTAN; match class: 1 0.029285011881787 5350 53 25 0.471698113207547 0.00467289719626168
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.0293212463511059 13227 60 51 0.85 0.0038557496030846
TF TF:M02053_1 Factor: ELF1; motif: NCCGGAARTN; match class: 1 0.0294967809305756 1559 57 12 0.210526315789474 0.00769724182168056
TF TF:M02070_1 Factor: TEL1; motif: CNCGGAANNN; match class: 1 0.0296841061536098 4841 61 26 0.426229508196721 0.00537079115885148
TF TF:M11421 Factor: ER81; motif: NACCGGAAGTN 0.0296841061536098 2341 55 15 0.272727272727273 0.00640751815463477
TF TF:M12310 Factor: ZNF597; motif: NGCCGCCATTTTGN 0.0296841061536098 437 56 6 0.107142857142857 0.0137299771167048
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 0.0296841061536098 14575 61 55 0.901639344262295 0.00377358490566038
TF TF:M11449 Factor: Elf-1; motif: NANCCGGAAGTN 0.0296971717956193 4305 61 24 0.39344262295082 0.00557491289198606
TF TF:M10107_1 Factor: DB1; motif: GGRRRRGRRGGAGGGGGNGRRR; match class: 1 0.0296971717956193 2657 5 4 0.8 0.0015054572826496
TF TF:M05327_1 Factor: WT1; motif: NGCGGGGGGGTSMMCYN; match class: 1 0.030003148961339 1757 58 13 0.224137931034483 0.00739897552646557
TF TF:M11179 Factor: ASH-2; motif: ACACGACGCN 0.0300126421945064 2162 13 6 0.461538461538462 0.00277520814061055
TF TF:M09918_1 Factor: Pet-1; motif: GCNGGAAGYG; match class: 1 0.0301410565965604 7159 61 34 0.557377049180328 0.00474926665735438
TF TF:M00716 Factor: ZF5; motif: GSGCGCGR 0.0302160354331253 16103 32 32 1 0.0019872073526672
TF TF:M11389 Factor: elf5; motif: GAMCCGGAAGTN 0.0305128504396107 1308 59 11 0.186440677966102 0.00840978593272171
TF TF:M04690_1 Factor: C/EBPbeta; motif: RTTGCGCAA; match class: 1 0.0305653991158062 3547 24 11 0.458333333333333 0.00310121229207781
TF TF:M10529_1 Factor: Sp1; motif: RGGGMGGRGSNGGGG; match class: 1 0.0305653991158062 2816 56 17 0.303571428571429 0.00603693181818182
TF TF:M11452 Factor: Elf-1; motif: NANGCGGAAGTR 0.0305653991158062 6276 61 31 0.508196721311475 0.00493945188017846
TF TF:M00736_1 Factor: E2F-1:DP-1; motif: TTTCSCGC; match class: 1 0.0307000898936454 4639 48 21 0.4375 0.0045268376805346
TF TF:M11450_1 Factor: Elf-1; motif: NANSCGGAAGTR; match class: 1 0.0311865332154402 1315 59 11 0.186440677966102 0.00836501901140684
TF TF:M00360 Factor: Pax-3; motif: TCGTCACRCTTHM 0.0311865332154402 12238 47 39 0.829787234042553 0.00318679522797843
TF TF:M11313 Factor: CREBPA; motif: NRTGACGTMANN 0.0312262372439127 3680 30 13 0.433333333333333 0.00353260869565217
TF TF:M10086 Factor: TAFII250; motif: RARRWGGCGGMGGNGR 0.0312640597500425 9262 60 40 0.666666666666667 0.00431872165838912
TF TF:M03924 Factor: YY1; motif: NNCGCCATTNN 0.0315247100314213 10084 61 43 0.704918032786885 0.00426418088060294
TF TF:M08458_1 Factor: Erm:C/EBPdelta; motif: RSCGGAWRTTGCGYAAY; match class: 1 0.0322075502729586 3168 7 5 0.714285714285714 0.00157828282828283
TF TF:M07052 Factor: NRF-1; motif: GCGCMTGCGCN 0.0328858063074269 2130 61 15 0.245901639344262 0.00704225352112676
TF TF:M00117 Factor: C/EBPbeta; motif: NKNTTGCNYAAYNN 0.033362303956423 4147 40 17 0.425 0.00409934892693513
TF TF:M08941_1 Factor: C-JUN:FRA-2; motif: NRTGACGTMAT; match class: 1 0.0334263550802008 3353 22 10 0.454545454545455 0.00298240381747689
TF TF:M08392_1 Factor: A-Myb:TBR2; motif: NNGTGNNNAACGG; match class: 1 0.0342221179604912 111 43 3 0.0697674418604651 0.027027027027027
TF TF:M09896 Factor: E2F-7; motif: GRGGCGGGAANNN 0.034432349032684 9927 52 37 0.711538461538462 0.00372720862294752
TF TF:M01816 Factor: ZBP89; motif: YCCYCCCCCM 0.0345711045905785 2194 27 9 0.333333333333333 0.004102096627165
TF TF:M11849_1 Factor: MR; motif: NGNACRNNNYGTNCN; match class: 1 0.0346818046566 4264 49 20 0.408163265306122 0.00469043151969981
TF TF:M11306 Factor: ATF-2; motif: NRTGAYGTMAYN 0.0346818046566 3378 22 10 0.454545454545455 0.0029603315571344
TF TF:M07084 Factor: E2F-4; motif: NGGCGGGAARN 0.0351058751227781 10834 61 45 0.737704918032787 0.00415359054827395
TF TF:M09611 Factor: ER81; motif: NNNGRCMGGAAGYRNNNNNNNS 0.0355063630236026 2666 60 17 0.283333333333333 0.00637659414853713
TF TF:M04826 Factor: p300; motif: ACNTCCG 0.0355063630236026 17806 61 61 1 0.00342581152420532
TF TF:M11437_1 Factor: SAP-1; motif: NRCCGGAWGYN; match class: 1 0.0355063630236026 456 39 5 0.128205128205128 0.0109649122807018
TF TF:M02072 Factor: Pet-1; motif: ACCGGAWRTN 0.0355063630236026 2395 50 14 0.28 0.0058455114822547
TF TF:M10108_1 Factor: WT1; motif: RGGNGGGGGAGGRGGNGGRG; match class: 1 0.0356327213710365 2864 5 4 0.8 0.00139664804469274
TF TF:M09834_1 Factor: ZNF148; motif: NNNNNNCCNNCCCCTCCCCCACCCN; match class: 1 0.0356448746124286 2869 5 4 0.8 0.00139421401185082
TF TF:M01471_1 Factor: Lhx3; motif: NNAATTAATTAAWWNNN; match class: 1 0.0356448746124286 897 40 7 0.175 0.00780379041248606
TF TF:M11009 Factor: LHX4; motif: NTAATTAN 0.0356513916088264 902 40 7 0.175 0.00776053215077605
TF TF:M01078_1 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN; match class: 1 0.0356513916088264 2448 39 12 0.307692307692308 0.00490196078431373
TF TF:M11007 Factor: LHX4; motif: NTAATTAN 0.0356513916088264 902 40 7 0.175 0.00776053215077605
TF TF:M10119 Factor: REX-1; motif: GGCMGCCATTTT 0.0356513916088264 1888 56 13 0.232142857142857 0.00688559322033898
TF TF:M10998 Factor: LMX1A; motif: TTAATTAN 0.0356513916088264 902 40 7 0.175 0.00776053215077605
TF TF:M09900 Factor: Elf-1; motif: NNANCCGGAAGTGS 0.0356513916088264 5219 61 27 0.442622950819672 0.00517340486683273
TF TF:M10992 Factor: lmx1b; motif: NNNTTAATTAN 0.0356513916088264 447 40 5 0.125 0.0111856823266219
TF TF:M08982 Factor: YY1; motif: NAANATGGCGNNN 0.0356513916088264 7125 51 29 0.568627450980392 0.00407017543859649
TF TF:M11007_1 Factor: LHX4; motif: NTAATTAN; match class: 1 0.0356513916088264 902 40 7 0.175 0.00776053215077605
TF TF:M00427_1 Factor: E2F; motif: TTTSGCGS; match class: 1 0.0360150967315268 3831 47 18 0.382978723404255 0.00469851213782302
TF TF:M08982_1 Factor: YY1; motif: NAANATGGCGNNN; match class: 1 0.0368740971113351 1662 42 10 0.238095238095238 0.00601684717208183
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.0369245137603696 11232 61 46 0.754098360655738 0.0040954415954416
TF TF:M01865 Factor: BTEB3; motif: BNRNGGGAGGNGT 0.0371751032641805 9899 25 20 0.8 0.00202040610162643
TF TF:M08229 Factor: Elk-1:SREBP-2; motif: RTCACGTGACCGGAAGN 0.0371751032641805 9535 54 37 0.685185185185185 0.00388044048243314
TF TF:M07258 Factor: HOXD10; motif: ARGAATAAWAA 0.037350313664333 849 32 6 0.1875 0.00706713780918728
TF TF:M04691 Factor: Kaiso; motif: TCTCGCGAG 0.0375138792329829 15113 23 23 1 0.00152186858995567
TF TF:M01714_1 Factor: KLF15; motif: GAGNNGGGGNGTDG; match class: 1 0.0381490455745711 209 52 4 0.0769230769230769 0.0191387559808612
TF TF:M12313 Factor: ZNF460; motif: NNACNCCCCCCNN 0.0383059319952994 5825 5 5 1 0.000858369098712446
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.0386471313058981 4056 59 22 0.372881355932203 0.00542406311637081
TF TF:M07986 Factor: DMRT3; motif: NATGTATCAAN 0.0386471313058981 195 56 4 0.0714285714285714 0.0205128205128205
TF TF:M09632 Factor: Kaiso; motif: GNTCTCGCGAGRNNNNGGN 0.0397499823361679 3001 5 4 0.8 0.00133288903698767
TF TF:M08281 Factor: Fli-1:C/EBPbeta; motif: RNCGGAWRTTGCGCAAY 0.0405584960294867 7571 23 16 0.695652173913043 0.00211332716946242
TF TF:M11485_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.0410031460069825 6203 12 9 0.75 0.00145091084958891
TF TF:M03971 Factor: ELK1; motif: NACTTCCGSCGGAAGYN 0.0412190057876186 11293 61 46 0.754098360655738 0.00407331975560081
TF TF:M12142 Factor: Egr-2; motif: NMCGCCCACGCNN 0.0415259626607059 953 61 9 0.147540983606557 0.00944386149003148
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.0415259626607059 10253 61 43 0.704918032786885 0.00419389446991125
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.0417793743257897 11423 59 45 0.76271186440678 0.0039394204674779
TF TF:M00040_1 Factor: ATF-2; motif: TTACGTAA; match class: 1 0.0417793743257897 6460 35 20 0.571428571428571 0.00309597523219814
TF TF:M00228 Factor: VBP; motif: GTTACRTMAT 0.0426881501207949 2565 29 10 0.344827586206897 0.00389863547758285
TF TF:M04110 Factor: RUNX3; motif: NRACCGCANWAACCRCAN 0.042766412500882 9266 61 40 0.655737704918033 0.00431685732786531
TF TF:M11486_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.042874729999092 2952 11 6 0.545454545454545 0.00203252032520325
TF TF:M10948 Factor: rax; motif: NNCRTTAN 0.0429900612441957 11816 59 46 0.779661016949153 0.00389302640487475
TF TF:M03925 Factor: YY2; motif: NCCGCCATNTY 0.0430359599165741 4641 56 23 0.410714285714286 0.00495582848524025
TF TF:M04950_1 Factor: Egr-1; motif: NGCGTGCGY; match class: 1 0.0432918839916458 5551 11 8 0.727272727272727 0.00144118176905062
TF TF:M11077_1 Factor: TCFL5; motif: KCACGCGCMC; match class: 1 0.0432918839916458 100 55 3 0.0545454545454545 0.03
TF TF:M03965 Factor: EHF; motif: NACCCGGAAGTA 0.0432918839916458 389 49 5 0.102040816326531 0.012853470437018
TF TF:M11382_1 Factor: ESE-1; motif: NWTRCGGAWGCN; match class: 1 0.0432918839916458 4112 59 22 0.372881355932203 0.00535019455252918
TF TF:M08290 Factor: FOXJ2:Elf-1; motif: NNAAACMGGAAGTN 0.0432918839916458 1598 45 10 0.222222222222222 0.00625782227784731
TF TF:M08423_1 Factor: TEF-3:ER81; motif: ACCGGAAATRCC; match class: 1 0.043661144307447 654 43 6 0.13953488372093 0.00917431192660551
TF TF:M00738_1 Factor: E2F-4:DP-1; motif: TTTSGCGC; match class: 1 0.043661144307447 3999 23 11 0.478260869565217 0.00275068767191798
TF TF:M00024 Factor: E2F-1; motif: TWSGCGCGAAAAYKR 0.043661144307447 8919 29 21 0.724137931034483 0.00235452404978137
TF TF:M11381 Factor: ESE-1; motif: SATKGCGGATGCN 0.0442049368338267 15720 61 57 0.934426229508197 0.00362595419847328
TF TF:M08470_1 Factor: Fli-1:Dlx-2; motif: RNCGGAARYAATTA; match class: 1 0.0445040253467838 1207 59 10 0.169491525423729 0.00828500414250207
TF TF:M04696 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN 0.0445040253467838 7819 48 29 0.604166666666667 0.00370891418339941
TF TF:M07234_1 Factor: YY1; motif: CAARATGGCNGC; match class: 1 0.0445155533756363 1177 33 7 0.212121212121212 0.00594732370433305
TF TF:M11296 Factor: jdp2; motif: NRTGAYGTCAYN 0.044579998643012 2950 22 9 0.409090909090909 0.00305084745762712
TF TF:M02102 Factor: NRF-1; motif: YGCGCMTGCGC 0.045254571744463 2020 61 14 0.229508196721311 0.00693069306930693
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.0460798947748012 14593 52 47 0.903846153846154 0.00322072226409923
TF TF:M00033 Factor: p300; motif: NNNGGGAGTNNNNS 0.0463254031983748 8577 30 21 0.7 0.00244840853445261
TF TF:M11398 Factor: Fli-1; motif: NACMGGAARTN 0.0463434657893566 2389 22 8 0.363636363636364 0.00334868145667643
TF TF:M11312 Factor: CREBPA; motif: NRTGAYGTCATN 0.0472449475263516 260 46 4 0.0869565217391304 0.0153846153846154
TF TF:M08867_1 Factor: AP2; motif: GCCYGSGGSN; match class: 1 0.0472449475263516 5186 60 26 0.433333333333333 0.00501349787890474
TF TF:M00744_1 Factor: POU1F1; motif: ATGAATAAWT; match class: 1 0.0476859852786322 351 17 3 0.176470588235294 0.00854700854700855
TF TF:M11231 Factor: CREBL1; motif: GRTGACGTCAYC 0.047839175172683 1057 28 6 0.214285714285714 0.00567644276253548
TF TF:M00291 Factor: Freac-3; motif: NNNNNGTAAATAAACA 0.047839175172683 5278 34 17 0.5 0.00322091701402046
TF TF:M03924_1 Factor: YY1; motif: NNCGCCATTNN; match class: 1 0.047839175172683 3700 54 19 0.351851851851852 0.00513513513513513
TF TF:M11422_1 Factor: Erm; motif: NRCMGGAAGTN; match class: 1 0.047839175172683 934 7 3 0.428571428571429 0.00321199143468951
TF TF:M03995 Factor: SPIB; motif: NAAAAGMGGAAGTN 0.0479029411291251 759 51 7 0.137254901960784 0.00922266139657444
TF TF:M00940_1 Factor: E2F-1; motif: NTTTCGCGCS; match class: 1 0.048030274553168 2643 48 14 0.291666666666667 0.00529701097237987
TF TF:M11478 Factor: AP-2beta; motif: NSCCNNNGGSN 0.048030274553168 9942 48 34 0.708333333333333 0.00341983504325086
TF TF:M10749 Factor: gsh-1; motif: NTCRTTAN 0.0481972160336963 5576 51 24 0.470588235294118 0.00430416068866571
TF TF:M01298 Factor: MECP2; motif: CCGGSNNNANNAWWT 0.0481972160336963 1290 31 7 0.225806451612903 0.00542635658914729
TF TF:M10566 Factor: Msx-1; motif: NTCRTTAN 0.0481972160336963 5576 51 24 0.470588235294118 0.00430416068866571
TF TF:M11485 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.0481972160336963 6977 60 32 0.533333333333333 0.00458649849505518
TF TF:M10572 Factor: Gbx2; motif: NTCRTTAN 0.0481972160336963 5576 51 24 0.470588235294118 0.00430416068866571
TF TF:M08239 Factor: ERF:FOXI1; motif: RNAAACMGGAARTN 0.048714473104225 2246 56 14 0.25 0.006233303650935
TF TF:M08390 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA 0.0489100362398357 11072 61 45 0.737704918032787 0.0040643063583815
TF TF:M09895_1 Factor: E2F-6; motif: NGGGCGGGARRNN; match class: 1 0.0490167876542524 2711 52 15 0.288461538461538 0.00553301364810033
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 0.0490472460206917 16263 61 58 0.950819672131147 0.00356637766709709
TF TF:M10849 Factor: Cdx-2; motif: NRTCGTAANNNN 0.049167901298554 11163 38 30 0.789473684210526 0.00268744961031981
TF TF:M01035_1 Factor: YY1; motif: NYNKCCATNTT; match class: 1 0.0493879095101723 1112 12 4 0.333333333333333 0.00359712230215827
TF TF:M00736 Factor: E2F-1:DP-1; motif: TTTCSCGC 0.0494658113062088 10390 61 43 0.704918032786885 0.0041385948026949
TF TF:M11993 Factor: NFATc4; motif: NAYGGAAANW 0.0498088954232897 944 42 7 0.166666666666667 0.00741525423728814
WP WP:WP138 Androgen receptor signaling pathway 0.00399472208682243 90 7 3 0.428571428571429 0.0333333333333333

pEpi27 transcription factor target enrichment of top program genes

TF enrichment of pEpi27
Possible regulators of activation of pEpi27 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.