pTNI06 program activity among T/NK/ILC cells

Activation of pTNI06
pTNI06 gene program activation in T/NK/ILC cells.
Gene program activation of pTNI06 by different cell subtypes
pTNI06 gene program activation among cells of different subtypes (T/NK/ILC cells).

pTNI06 top program genes

Top genes of pTNI06 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pTNI06 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pTNI06
pTNI06 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.32106643247611e-14 103 20 10 0.5 0.0970873786407767
GO:BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 5.82724963291623e-13 96 20 9 0.45 0.09375
GO:BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 5.82724963291623e-13 100 20 9 0.45 0.09
GO:BP GO:0042110 T cell activation 8.11287116347066e-13 489 69 20 0.289855072463768 0.0408997955010225
GO:BP GO:0002250 adaptive immune response 2.27273302584139e-12 689 15 12 0.8 0.0174165457184325
GO:BP GO:0006955 immune response 9.08879464790181e-12 2311 90 41 0.455555555555556 0.0177412375594981
GO:BP GO:0019882 antigen processing and presentation 9.08879464790181e-12 234 20 10 0.5 0.0427350427350427
GO:BP GO:0050863 regulation of T cell activation 1.70150835922005e-11 337 65 16 0.246153846153846 0.0474777448071217
GO:BP GO:0050776 regulation of immune response 2.84609079220773e-11 996 63 23 0.365079365079365 0.0230923694779116
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 2.84609079220773e-11 174 20 9 0.45 0.0517241379310345
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 2.84609079220773e-11 88 13 7 0.538461538461538 0.0795454545454545
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 3.61539469925053e-11 182 20 9 0.45 0.0494505494505494
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 5.04078493713708e-11 192 20 9 0.45 0.046875
GO:BP GO:0034341 response to interferon-gamma 5.04078493713708e-11 196 13 8 0.615384615384615 0.0408163265306122
GO:BP GO:0046649 lymphocyte activation 2.00625063108179e-10 771 71 21 0.295774647887324 0.0272373540856031
GO:BP GO:0002503 peptide antigen assembly with MHC class II protein complex 2.11240432734687e-10 4 20 4 0.2 1
GO:BP GO:0002399 MHC class II protein complex assembly 2.11240432734687e-10 4 20 4 0.2 1
GO:BP GO:0050778 positive regulation of immune response 2.55044297687593e-10 753 90 23 0.255555555555556 0.0305444887118194
GO:BP GO:0007159 leukocyte cell-cell adhesion 2.70360152341421e-10 375 42 13 0.30952380952381 0.0346666666666667
GO:BP GO:1903037 regulation of leukocyte cell-cell adhesion 1.62979165558731e-09 338 42 12 0.285714285714286 0.0355029585798817
GO:BP GO:0051249 regulation of lymphocyte activation 1.71860768451588e-09 518 71 17 0.23943661971831 0.0328185328185328
GO:BP GO:0071346 cellular response to interferon-gamma 1.71860768451588e-09 175 13 7 0.538461538461538 0.04
GO:BP GO:0045321 leukocyte activation 1.84776962357295e-09 1332 125 34 0.272 0.0255255255255255
GO:BP GO:0030217 T cell differentiation 2.12765922449381e-09 260 69 13 0.188405797101449 0.05
GO:BP GO:0002501 peptide antigen assembly with MHC protein complex 2.15160818777093e-09 6 20 4 0.2 0.666666666666667
GO:BP GO:0050870 positive regulation of T cell activation 2.58318174901715e-09 219 7 6 0.857142857142857 0.0273972602739726
GO:BP GO:0002376 immune system process 2.99064310903807e-09 3278 90 44 0.488888888888889 0.0134228187919463
GO:BP GO:0001775 cell activation 2.99064310903807e-09 1495 71 26 0.366197183098592 0.0173913043478261
GO:BP GO:0002684 positive regulation of immune system process 3.46862046422023e-09 1065 15 11 0.733333333333333 0.0103286384976526
GO:BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 3.99712002644356e-09 241 7 6 0.857142857142857 0.024896265560166
GO:BP GO:0002396 MHC protein complex assembly 4.045863858067e-09 7 20 4 0.2 0.571428571428571
GO:BP GO:0050865 regulation of cell activation 4.61698120488592e-09 655 71 18 0.253521126760563 0.0274809160305344
GO:BP GO:0030098 lymphocyte differentiation 4.61698120488592e-09 376 90 16 0.177777777777778 0.0425531914893617
GO:BP GO:0050852 T cell receptor signaling pathway 6.28102839039257e-09 203 14 7 0.5 0.0344827586206897
GO:BP GO:0002682 regulation of immune system process 8.93214925063962e-09 1617 65 25 0.384615384615385 0.015460729746444
GO:BP GO:0022409 positive regulation of cell-cell adhesion 8.98732009631403e-09 284 7 6 0.857142857142857 0.0211267605633803
GO:BP GO:0002694 regulation of leukocyte activation 1.26359997959635e-08 610 71 17 0.23943661971831 0.0278688524590164
GO:BP GO:0007155 cell adhesion 1.45905469430575e-08 1492 56 22 0.392857142857143 0.014745308310992
GO:BP GO:0022610 biological adhesion 1.5557375926516e-08 1499 56 22 0.392857142857143 0.0146764509673115
GO:BP GO:0022407 regulation of cell-cell adhesion 1.96316120715178e-08 445 42 12 0.285714285714286 0.0269662921348315
GO:BP GO:1903131 mononuclear cell differentiation 2.43905499491063e-08 430 27 10 0.37037037037037 0.0232558139534884
GO:BP GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 2.73112942467374e-08 5 7 3 0.428571428571429 0.6
GO:BP GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 2.73112942467374e-08 5 7 3 0.428571428571429 0.6
GO:BP GO:0002468 dendritic cell antigen processing and presentation 2.75013900603012e-08 14 3 3 1 0.214285714285714
GO:BP GO:0030155 regulation of cell adhesion 2.75013900603012e-08 748 28 12 0.428571428571429 0.0160427807486631
GO:BP GO:0051251 positive regulation of lymphocyte activation 3.19507631538399e-08 365 7 6 0.857142857142857 0.0164383561643836
GO:BP GO:0045087 innate immune response 4.0631886364785e-08 998 15 10 0.666666666666667 0.0100200400801603
GO:BP GO:0006952 defense response 4.60808081407852e-08 1818 124 37 0.298387096774194 0.0203520352035204
GO:BP GO:0002696 positive regulation of leukocyte activation 6.21928945942671e-08 412 7 6 0.857142857142857 0.0145631067961165
GO:BP GO:0045580 regulation of T cell differentiation 6.89070646624877e-08 152 57 9 0.157894736842105 0.0592105263157895
GO:BP GO:0050867 positive regulation of cell activation 7.10196342161863e-08 424 7 6 0.857142857142857 0.0141509433962264
GO:BP GO:0045785 positive regulation of cell adhesion 8.35270331875041e-08 437 7 6 0.857142857142857 0.0137299771167048
GO:BP GO:0002521 leukocyte differentiation 9.3080653079554e-08 550 90 17 0.188888888888889 0.0309090909090909
GO:BP GO:0050851 antigen receptor-mediated signaling pathway 1.01910915370843e-07 323 14 7 0.5 0.021671826625387
GO:BP GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 1.19514405200786e-07 8 7 3 0.428571428571429 0.375
GO:BP GO:0019883 antigen processing and presentation of endogenous antigen 1.55837467359742e-07 26 3 3 1 0.115384615384615
GO:BP GO:0098609 cell-cell adhesion 1.6778069649465e-07 894 53 16 0.30188679245283 0.0178970917225951
GO:BP GO:0048584 positive regulation of response to stimulus 2.2548322284484e-07 2344 28 17 0.607142857142857 0.00725255972696246
GO:BP GO:0098542 defense response to other organism 2.25685475115346e-07 1218 15 10 0.666666666666667 0.00821018062397373
GO:BP GO:0045619 regulation of lymphocyte differentiation 2.27919800079115e-07 180 15 6 0.4 0.0333333333333333
GO:BP GO:0051707 response to other organism 2.58679070735214e-07 1592 124 33 0.266129032258065 0.0207286432160804
GO:BP GO:0043207 response to external biotic stimulus 2.62591237213812e-07 1594 124 33 0.266129032258065 0.020702634880803
GO:BP GO:0009607 response to biotic stimulus 4.23126539382471e-07 1626 124 33 0.266129032258065 0.0202952029520295
GO:BP GO:0050670 regulation of lymphocyte proliferation 4.51839229714721e-07 230 65 10 0.153846153846154 0.0434782608695652
GO:BP GO:0032944 regulation of mononuclear cell proliferation 4.83269616381688e-07 232 65 10 0.153846153846154 0.0431034482758621
GO:BP GO:0042129 regulation of T cell proliferation 6.12533323972381e-07 176 87 10 0.114942528735632 0.0568181818181818
GO:BP GO:0007166 cell surface receptor signaling pathway 6.76310096578193e-07 3210 90 39 0.433333333333333 0.0121495327102804
GO:BP GO:0045589 regulation of regulatory T cell differentiation 7.67380110201241e-07 35 15 4 0.266666666666667 0.114285714285714
GO:BP GO:0019221 cytokine-mediated signaling pathway 7.8401645754686e-07 810 13 8 0.615384615384615 0.00987654320987654
GO:BP GO:0050866 negative regulation of cell activation 8.32329358023726e-07 211 121 12 0.0991735537190083 0.0568720379146919
GO:BP GO:0070663 regulation of leukocyte proliferation 9.10396662241378e-07 251 65 10 0.153846153846154 0.0398406374501992
GO:BP GO:0002683 negative regulation of immune system process 9.10897433148667e-07 420 121 16 0.132231404958678 0.0380952380952381
GO:BP GO:0045582 positive regulation of T cell differentiation 9.13837245960479e-07 91 7 4 0.571428571428571 0.043956043956044
GO:BP GO:0002699 positive regulation of immune effector process 9.53981704568166e-07 215 27 7 0.259259259259259 0.0325581395348837
GO:BP GO:0045066 regulatory T cell differentiation 9.53981704568166e-07 38 15 4 0.266666666666667 0.105263157894737
GO:BP GO:0046651 lymphocyte proliferation 9.9539225343669e-07 294 90 12 0.133333333333333 0.0408163265306122
GO:BP GO:0031343 positive regulation of cell killing 9.9539225343669e-07 59 27 5 0.185185185185185 0.0847457627118644
GO:BP GO:0002757 immune response-activating signal transduction 9.95895641580543e-07 477 14 7 0.5 0.0146750524109015
GO:BP GO:0002429 immune response-activating cell surface receptor signaling pathway 9.95895641580543e-07 477 14 7 0.5 0.0146750524109015
GO:BP GO:0045591 positive regulation of regulatory T cell differentiation 9.95895641580543e-07 17 7 3 0.428571428571429 0.176470588235294
GO:BP GO:0032943 mononuclear cell proliferation 1.05982629792325e-06 297 90 12 0.133333333333333 0.0404040404040404
GO:BP GO:0002697 regulation of immune effector process 1.16607265789454e-06 461 99 15 0.151515151515152 0.0325379609544469
GO:BP GO:0045621 positive regulation of lymphocyte differentiation 1.38482777307173e-06 104 7 4 0.571428571428571 0.0384615384615385
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 1.54474117373984e-06 512 14 7 0.5 0.013671875
GO:BP GO:0002764 immune response-regulating signaling pathway 1.58946069584192e-06 515 14 7 0.5 0.0135922330097087
GO:BP GO:0002285 lymphocyte activation involved in immune response 1.59379774921137e-06 190 20 6 0.3 0.0315789473684211
GO:BP GO:0042098 T cell proliferation 1.74595914379152e-06 205 65 9 0.138461538461538 0.0439024390243902
GO:BP GO:0030097 hemopoiesis 1.74595914379152e-06 928 69 17 0.246376811594203 0.0183189655172414
GO:BP GO:0002286 T cell activation involved in immune response 1.74595914379152e-06 112 7 4 0.571428571428571 0.0357142857142857
GO:BP GO:0002695 negative regulation of leukocyte activation 1.9168686168433e-06 188 121 11 0.0909090909090909 0.0585106382978723
GO:BP GO:1902105 regulation of leukocyte differentiation 1.9168686168433e-06 288 63 10 0.158730158730159 0.0347222222222222
GO:BP GO:0051250 negative regulation of lymphocyte activation 2.11255358475532e-06 156 87 9 0.103448275862069 0.0576923076923077
GO:BP GO:0002253 activation of immune response 2.14708546387446e-06 568 63 13 0.206349206349206 0.022887323943662
GO:BP GO:0034097 response to cytokine 2.15969370216197e-06 1226 88 22 0.25 0.0179445350734095
GO:BP GO:0070661 leukocyte proliferation 2.43650706539649e-06 325 90 12 0.133333333333333 0.0369230769230769
GO:BP GO:0071345 cellular response to cytokine stimulus 2.58178018489801e-06 1132 88 21 0.238636363636364 0.0185512367491166
GO:BP GO:0001817 regulation of cytokine production 2.68022104696495e-06 806 121 21 0.173553719008264 0.0260545905707196
GO:BP GO:0048534 hematopoietic or lymphoid organ development 2.83942169907273e-06 966 69 17 0.246376811594203 0.0175983436853002
GO:BP GO:0046637 regulation of alpha-beta T cell differentiation 2.89210068004339e-06 68 12 4 0.333333333333333 0.0588235294117647
GO:BP GO:0006954 inflammatory response 3.12666763746639e-06 794 124 21 0.169354838709677 0.026448362720403
GO:BP GO:0046634 regulation of alpha-beta T cell activation 3.94598699192755e-06 102 42 6 0.142857142857143 0.0588235294117647
GO:BP GO:0050868 negative regulation of T cell activation 4.28346696723802e-06 123 87 8 0.0919540229885057 0.0650406504065041
GO:BP GO:0001816 cytokine production 5.46819444365197e-06 844 121 21 0.173553719008264 0.0248815165876777
GO:BP GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 5.47070625403552e-06 32 7 3 0.428571428571429 0.09375
GO:BP GO:0002520 immune system development 5.68076797827154e-06 1020 69 17 0.246376811594203 0.0166666666666667
GO:BP GO:1902107 positive regulation of leukocyte differentiation 5.68076797827154e-06 157 7 4 0.571428571428571 0.0254777070063694
GO:BP GO:1903708 positive regulation of hemopoiesis 5.68076797827154e-06 157 7 4 0.571428571428571 0.0254777070063694
GO:BP GO:0032649 regulation of interferon-gamma production 5.79743490607044e-06 110 42 6 0.142857142857143 0.0545454545454545
GO:BP GO:0009605 response to external stimulus 6.03660388582838e-06 2944 75 31 0.413333333333333 0.0105298913043478
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 6.1355906049011e-06 2255 90 30 0.333333333333333 0.0133037694013304
GO:BP GO:0007162 negative regulation of cell adhesion 6.5828069546403e-06 304 87 11 0.126436781609195 0.0361842105263158
GO:BP GO:0031341 regulation of cell killing 6.88763747392707e-06 93 27 5 0.185185185185185 0.0537634408602151
GO:BP GO:0032609 interferon-gamma production 7.22297523598348e-06 115 42 6 0.142857142857143 0.0521739130434783
GO:BP GO:0006950 response to stress 7.68003630692277e-06 4170 79 39 0.493670886075949 0.00935251798561151
GO:BP GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 8.42143782745819e-06 38 7 3 0.428571428571429 0.0789473684210526
GO:BP GO:0050671 positive regulation of lymphocyte proliferation 1.04890521682154e-05 141 20 5 0.25 0.0354609929078014
GO:BP GO:0032946 positive regulation of mononuclear cell proliferation 1.07737970273922e-05 142 20 5 0.25 0.0352112676056338
GO:BP GO:0050896 response to stimulus 1.08685407544058e-05 9407 81 64 0.790123456790123 0.00680344424364835
GO:BP GO:1903038 negative regulation of leukocyte cell-cell adhesion 1.08685407544058e-05 142 87 8 0.0919540229885057 0.0563380281690141
GO:BP GO:0070665 positive regulation of leukocyte proliferation 1.59794547345173e-05 155 20 5 0.25 0.032258064516129
GO:BP GO:1903706 regulation of hemopoiesis 1.73839435015132e-05 424 15 6 0.4 0.0141509433962264
GO:BP GO:0046638 positive regulation of alpha-beta T cell differentiation 1.77107741791717e-05 50 7 3 0.428571428571429 0.06
GO:BP GO:0046632 alpha-beta T cell differentiation 1.77107741791717e-05 113 12 4 0.333333333333333 0.0353982300884956
GO:BP GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 1.8669848655911e-05 51 7 3 0.428571428571429 0.0588235294117647
GO:BP GO:0046631 alpha-beta T cell activation 2.00526798862215e-05 155 87 8 0.0919540229885057 0.0516129032258065
GO:BP GO:0048583 regulation of response to stimulus 2.14509812827547e-05 4278 28 19 0.678571428571429 0.00444132772323516
GO:BP GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 2.22041737621903e-05 68 87 6 0.0689655172413793 0.0882352941176471
GO:BP GO:0001912 positive regulation of leukocyte mediated cytotoxicity 2.31272149784229e-05 51 27 4 0.148148148148148 0.0784313725490196
GO:BP GO:0002293 alpha-beta T cell differentiation involved in immune response 2.3691434742469e-05 69 87 6 0.0689655172413793 0.0869565217391304
GO:BP GO:0002287 alpha-beta T cell activation involved in immune response 2.3691434742469e-05 69 87 6 0.0689655172413793 0.0869565217391304
GO:BP GO:0002449 lymphocyte mediated immunity 2.75988295094487e-05 354 71 10 0.140845070422535 0.0282485875706215
GO:BP GO:0002763 positive regulation of myeloid leukocyte differentiation 2.75988295094487e-05 59 7 3 0.428571428571429 0.0508474576271186
GO:BP GO:0070887 cellular response to chemical stimulus 3.65748826738258e-05 3393 89 36 0.404494382022472 0.0106100795755968
GO:BP GO:0002292 T cell differentiation involved in immune response 3.69864800910442e-05 75 87 6 0.0689655172413793 0.08
GO:BP GO:0046635 positive regulation of alpha-beta T cell activation 3.81394200654648e-05 67 7 3 0.428571428571429 0.0447761194029851
GO:BP GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 3.81394200654648e-05 67 7 3 0.428571428571429 0.0447761194029851
GO:BP GO:0051240 positive regulation of multicellular organismal process 3.9209094091887e-05 1455 7 6 0.857142857142857 0.00412371134020619
GO:BP GO:0002252 immune effector process 4.49698027658212e-05 1309 123 25 0.203252032520325 0.0190985485103132
GO:BP GO:0051716 cellular response to stimulus 5.90498914671276e-05 7781 42 33 0.785714285714286 0.00424110011566637
GO:BP GO:0002708 positive regulation of lymphocyte mediated immunity 7.16687924947042e-05 104 71 6 0.0845070422535211 0.0576923076923077
GO:BP GO:0043367 CD4-positive, alpha-beta T cell differentiation 7.22619808243411e-05 85 87 6 0.0689655172413793 0.0705882352941176
GO:BP GO:0042102 positive regulation of T cell proliferation 8.72374439175466e-05 104 42 5 0.119047619047619 0.0480769230769231
GO:BP GO:0002366 leukocyte activation involved in immune response 8.79965932841419e-05 717 42 10 0.238095238095238 0.0139470013947001
GO:BP GO:0001910 regulation of leukocyte mediated cytotoxicity 8.87855575770681e-05 74 27 4 0.148148148148148 0.0540540540540541
GO:BP GO:0022408 negative regulation of cell-cell adhesion 8.93326296510487e-05 194 87 8 0.0919540229885057 0.0412371134020619
GO:BP GO:0002263 cell activation involved in immune response 9.01402619962034e-05 721 42 10 0.238095238095238 0.013869625520111
GO:BP GO:0001906 cell killing 0.000111484484320249 175 27 5 0.185185185185185 0.0285714285714286
GO:BP GO:0001819 positive regulation of cytokine production 0.000120387294220779 452 115 13 0.11304347826087 0.0287610619469027
GO:BP GO:0045639 positive regulation of myeloid cell differentiation 0.000123843463272257 103 7 3 0.428571428571429 0.029126213592233
GO:BP GO:0035710 CD4-positive, alpha-beta T cell activation 0.00012673271493915 104 7 3 0.428571428571429 0.0288461538461538
GO:BP GO:0098883 synapse pruning 0.000129100104046742 11 63 3 0.0476190476190476 0.272727272727273
GO:BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.000157025795788361 363 3 3 1 0.00826446280991736
GO:BP GO:0002705 positive regulation of leukocyte mediated immunity 0.000161510752374933 122 71 6 0.0845070422535211 0.0491803278688525
GO:BP GO:0002761 regulation of myeloid leukocyte differentiation 0.000203802064589324 123 7 3 0.428571428571429 0.024390243902439
GO:BP GO:0010033 response to organic substance 0.000224091006400097 3412 18 12 0.666666666666667 0.00351699882766706
GO:BP GO:0071310 cellular response to organic substance 0.000228407649395785 2776 18 11 0.611111111111111 0.00396253602305476
GO:BP GO:0034205 amyloid-beta formation 0.000296742781772427 59 97 5 0.0515463917525773 0.0847457627118644
GO:BP GO:0032729 positive regulation of interferon-gamma production 0.000301020985602993 66 42 4 0.0952380952380952 0.0606060606060606
GO:BP GO:0042093 T-helper cell differentiation 0.000301020985602993 66 87 5 0.0574712643678161 0.0757575757575758
GO:BP GO:0001909 leukocyte mediated cytotoxicity 0.000335866271805444 107 27 4 0.148148148148148 0.0373831775700935
GO:BP GO:0043368 positive T cell selection 0.000391244055120838 38 26 3 0.115384615384615 0.0789473684210526
GO:BP GO:0042130 negative regulation of T cell proliferation 0.000391271373327867 70 87 5 0.0574712643678161 0.0714285714285714
GO:BP GO:0046007 negative regulation of activated T cell proliferation 0.000431557479246668 16 65 3 0.0461538461538462 0.1875
GO:BP GO:0010038 response to metal ion 0.000437096907461717 371 115 11 0.0956521739130435 0.0296495956873315
GO:BP GO:1901214 regulation of neuron death 0.000437549929827647 323 67 8 0.119402985074627 0.0247678018575851
GO:BP GO:0002706 regulation of lymphocyte mediated immunity 0.000441725531515662 151 42 5 0.119047619047619 0.033112582781457
GO:BP GO:0002443 leukocyte mediated immunity 0.000550920459961873 877 52 11 0.211538461538462 0.0125427594070696
GO:BP GO:0050435 amyloid-beta metabolic process 0.000554128124479701 68 97 5 0.0515463917525773 0.0735294117647059
GO:BP GO:0048518 positive regulation of biological process 0.000647341954787937 6363 18 15 0.833333333333333 0.00235737859500236
GO:BP GO:0042987 amyloid precursor protein catabolic process 0.000672784143423737 71 97 5 0.0515463917525773 0.0704225352112676
GO:BP GO:1901700 response to oxygen-containing compound 0.000771987534976659 1739 125 27 0.216 0.0155261644623347
GO:BP GO:0150146 cell junction disassembly 0.000860515429607269 21 63 3 0.0476190476190476 0.142857142857143
GO:BP GO:0010872 regulation of cholesterol esterification 0.000871623586506934 14 97 3 0.0309278350515464 0.214285714285714
GO:BP GO:0045058 T cell selection 0.000872448480288342 51 26 3 0.115384615384615 0.0588235294117647
GO:BP GO:0033993 response to lipid 0.000873873523174917 918 124 18 0.145161290322581 0.0196078431372549
GO:BP GO:0002573 myeloid leukocyte differentiation 0.000896286592665145 213 7 3 0.428571428571429 0.0140845070422535
GO:BP GO:0050672 negative regulation of lymphocyte proliferation 0.000907964592153739 85 87 5 0.0574712643678161 0.0588235294117647
GO:BP GO:0008284 positive regulation of cell population proliferation 0.000916336712926694 982 20 7 0.35 0.00712830957230143
GO:BP GO:0002830 positive regulation of type 2 immune response 0.000933430370564746 16 87 3 0.0344827586206897 0.1875
GO:BP GO:0032945 negative regulation of mononuclear cell proliferation 0.000941745273488638 86 87 5 0.0574712643678161 0.0581395348837209
GO:BP GO:0070997 neuron death 0.000941745273488638 365 67 8 0.119402985074627 0.0219178082191781
GO:BP GO:0042221 response to chemical 0.0010080945054049 4781 18 13 0.722222222222222 0.0027190964233424
GO:BP GO:0051241 negative regulation of multicellular organismal process 0.00106527621278117 1160 101 18 0.178217821782178 0.0155172413793103
GO:BP GO:0051239 regulation of multicellular organismal process 0.00112419140929886 2861 125 37 0.296 0.0129325410695561
GO:BP GO:0023052 signaling 0.00115319771733028 6810 92 53 0.576086956521739 0.00778267254038179
GO:BP GO:0007154 cell communication 0.00117902360267342 6829 71 43 0.605633802816901 0.00629667594084053
GO:BP GO:0070664 negative regulation of leukocyte proliferation 0.00124572490987147 92 87 5 0.0574712643678161 0.0543478260869565
GO:BP GO:0065003 protein-containing complex assembly 0.00143407916790449 1680 10 6 0.6 0.00357142857142857
GO:BP GO:0045637 regulation of myeloid cell differentiation 0.00151902496594363 263 7 3 0.428571428571429 0.0114068441064639
GO:BP GO:0002703 regulation of leukocyte mediated immunity 0.00158753423530089 205 42 5 0.119047619047619 0.024390243902439
GO:BP GO:0032496 response to lipopolysaccharide 0.00163712706115554 338 124 10 0.0806451612903226 0.029585798816568
GO:BP GO:0034433 steroid esterification 0.00164897904590369 18 97 3 0.0309278350515464 0.166666666666667
GO:BP GO:0034434 sterol esterification 0.00164897904590369 18 97 3 0.0309278350515464 0.166666666666667
GO:BP GO:0034435 cholesterol esterification 0.00164897904590369 18 97 3 0.0309278350515464 0.166666666666667
GO:BP GO:0045597 positive regulation of cell differentiation 0.00164897904590369 879 3 3 1 0.00341296928327645
GO:BP GO:0001818 negative regulation of cytokine production 0.00165384845804913 381 53 7 0.132075471698113 0.0183727034120735
GO:BP GO:0016064 immunoglobulin mediated immune response 0.00174907088970787 223 63 6 0.0952380952380952 0.0269058295964126
GO:BP GO:2000026 regulation of multicellular organismal development 0.00174907088970787 1447 16 7 0.4375 0.00483759502418798
GO:BP GO:0019724 B cell mediated immunity 0.00184991626189231 226 63 6 0.0952380952380952 0.0265486725663717
GO:BP GO:0032689 negative regulation of interferon-gamma production 0.00186527145107257 43 42 3 0.0714285714285714 0.0697674418604651
GO:BP GO:0032675 regulation of interleukin-6 production 0.00187615783166609 168 121 7 0.0578512396694215 0.0416666666666667
GO:BP GO:0016032 viral process 0.00192668411090036 942 3 3 1 0.00318471337579618
GO:BP GO:0071277 cellular response to calcium ion 0.00197732634737444 84 108 5 0.0462962962962963 0.0595238095238095
GO:BP GO:1902003 regulation of amyloid-beta formation 0.00199060481226544 50 97 4 0.0412371134020619 0.08
GO:BP GO:0032635 interleukin-6 production 0.00209213998029535 172 121 7 0.0578512396694215 0.0406976744186047
GO:BP GO:0002791 regulation of peptide secretion 0.00209213998029535 325 16 4 0.25 0.0123076923076923
GO:BP GO:0042127 regulation of cell population proliferation 0.00210374171025014 1774 7 5 0.714285714285714 0.0028184892897407
GO:BP GO:1902004 positive regulation of amyloid-beta formation 0.00210374171025014 20 97 3 0.0309278350515464 0.15
GO:BP GO:0042982 amyloid precursor protein metabolic process 0.00217703971052906 96 97 5 0.0515463917525773 0.0520833333333333
GO:BP GO:0044403 biological process involved in symbiotic interaction 0.002193788196392 1001 3 3 1 0.002997002997003
GO:BP GO:0045346 regulation of MHC class II biosynthetic process 0.002193788196392 16 125 3 0.024 0.1875
GO:BP GO:0009617 response to bacterium 0.00220522417207806 743 124 15 0.120967741935484 0.0201884253028264
GO:BP GO:0019058 viral life cycle 0.00229721572322499 353 61 7 0.114754098360656 0.0198300283286119
GO:BP GO:0002237 response to molecule of bacterial origin 0.00245003873285697 361 124 10 0.0806451612903226 0.0277008310249307
GO:BP GO:0045581 negative regulation of T cell differentiation 0.00251578039001544 49 42 3 0.0714285714285714 0.0612244897959184
GO:BP GO:0045342 MHC class II biosynthetic process 0.00256917745596217 17 125 3 0.024 0.176470588235294
GO:BP GO:0016477 cell migration 0.00267178178831827 1649 114 23 0.201754385964912 0.0139478471801092
GO:BP GO:0002720 positive regulation of cytokine production involved in immune response 0.00269010336938382 54 99 4 0.0404040404040404 0.0740740740740741
GO:BP GO:0002717 positive regulation of natural killer cell mediated immunity 0.0027036915456951 30 71 3 0.0422535211267606 0.1
GO:BP GO:0031589 cell-substrate adhesion 0.00274762244349253 367 28 5 0.178571428571429 0.0136239782016349
GO:BP GO:0043933 protein-containing complex subunit organization 0.00282187524842344 1963 10 6 0.6 0.00305654610290372
GO:BP GO:1902991 regulation of amyloid precursor protein catabolic process 0.00301184255633407 57 97 4 0.0412371134020619 0.0701754385964912
GO:BP GO:0010035 response to inorganic substance 0.00308878691781552 575 67 9 0.134328358208955 0.0156521739130435
GO:BP GO:1904064 positive regulation of cation transmembrane transport 0.00334456649991702 150 108 6 0.0555555555555556 0.04
GO:BP GO:0045833 negative regulation of lipid metabolic process 0.00340799074510139 108 97 5 0.0515463917525773 0.0462962962962963
GO:BP GO:0045620 negative regulation of lymphocyte differentiation 0.00366453258429644 57 42 3 0.0714285714285714 0.0526315789473684
GO:BP GO:1902993 positive regulation of amyloid precursor protein catabolic process 0.00369207129788473 25 97 3 0.0309278350515464 0.12
GO:BP GO:0008283 cell population proliferation 0.00376394507434132 2054 7 5 0.714285714285714 0.00243427458617332
GO:BP GO:0019725 cellular homeostasis 0.00391925325929151 981 112 16 0.142857142857143 0.0163098878695209
GO:BP GO:0002577 regulation of antigen processing and presentation 0.00392156529431565 21 120 3 0.025 0.142857142857143
GO:BP GO:0071887 leukocyte apoptotic process 0.00408424148007695 108 102 5 0.0490196078431373 0.0462962962962963
GO:BP GO:0007165 signal transduction 0.00410727235284755 6309 26 18 0.692307692307692 0.00285306704707561
GO:BP GO:0051055 negative regulation of lipid biosynthetic process 0.00425526937306378 64 97 4 0.0412371134020619 0.0625
GO:BP GO:0001774 microglial cell activation 0.00434703721792276 55 114 4 0.0350877192982456 0.0727272727272727
GO:BP GO:0002790 peptide secretion 0.00438243640292758 421 7 3 0.428571428571429 0.00712589073634204
GO:BP GO:0006695 cholesterol biosynthetic process 0.00438243640292758 74 85 4 0.0470588235294118 0.0540540540540541
GO:BP GO:0048259 regulation of receptor-mediated endocytosis 0.00438243640292758 112 101 5 0.0495049504950495 0.0446428571428571
GO:BP GO:1902653 secondary alcohol biosynthetic process 0.00438243640292758 74 85 4 0.0470588235294118 0.0540540540540541
GO:BP GO:0030100 regulation of endocytosis 0.00438243640292758 212 115 7 0.0608695652173913 0.0330188679245283
GO:BP GO:0051094 positive regulation of developmental process 0.00438243640292758 1341 3 3 1 0.00223713646532438
GO:BP GO:1901216 positive regulation of neuron death 0.00448351032811053 98 65 4 0.0615384615384615 0.0408163265306122
GO:BP GO:0030099 myeloid cell differentiation 0.00450803007712758 428 7 3 0.428571428571429 0.00700934579439252
GO:BP GO:0032673 regulation of interleukin-4 production 0.00457704116036085 31 87 3 0.0344827586206897 0.0967741935483871
GO:BP GO:0002828 regulation of type 2 immune response 0.00457704116036085 31 87 3 0.0344827586206897 0.0967741935483871
GO:BP GO:0032602 chemokine production 0.00462806067501411 101 114 5 0.043859649122807 0.0495049504950495
GO:BP GO:0071222 cellular response to lipopolysaccharide 0.00475157006695121 200 124 7 0.0564516129032258 0.035
GO:BP GO:0032633 interleukin-4 production 0.00497033961345551 32 87 3 0.0344827586206897 0.09375
GO:BP GO:1902106 negative regulation of leukocyte differentiation 0.00502463544388425 105 63 4 0.0634920634920635 0.0380952380952381
GO:BP GO:0032414 positive regulation of ion transmembrane transporter activity 0.00502989801411621 109 108 5 0.0462962962962963 0.0458715596330275
GO:BP GO:0045940 positive regulation of steroid metabolic process 0.00507755467728983 31 91 3 0.032967032967033 0.0967741935483871
GO:BP GO:0010628 positive regulation of gene expression 0.00508978195848232 1160 7 4 0.571428571428571 0.00344827586206897
GO:BP GO:0006509 membrane protein ectodomain proteolysis 0.00520706317423663 43 66 3 0.0454545454545455 0.0697674418604651
GO:BP GO:0042304 regulation of fatty acid biosynthetic process 0.00523218117682128 57 118 4 0.0338983050847458 0.0701754385964912
GO:BP GO:0046890 regulation of lipid biosynthetic process 0.00524748729982378 215 118 7 0.0593220338983051 0.0325581395348837
GO:BP GO:0016126 sterol biosynthetic process 0.00545064038809511 80 85 4 0.0470588235294118 0.05
GO:BP GO:0031347 regulation of defense response 0.00545064038809511 704 101 12 0.118811881188119 0.0170454545454545
GO:BP GO:1903707 negative regulation of hemopoiesis 0.0055469662214346 109 63 4 0.0634920634920635 0.036697247706422
GO:BP GO:0046006 regulation of activated T cell proliferation 0.0055469662214346 45 65 3 0.0461538461538462 0.0666666666666667
GO:BP GO:0050796 regulation of insulin secretion 0.00557115469807725 189 16 3 0.1875 0.0158730158730159
GO:BP GO:0070227 lymphocyte apoptotic process 0.00568857853136761 74 40 3 0.075 0.0405405405405405
GO:BP GO:0045939 negative regulation of steroid metabolic process 0.00581747345638738 31 97 3 0.0309278350515464 0.0967741935483871
GO:BP GO:0042088 T-helper 1 type immune response 0.00581747345638738 44 68 3 0.0441176470588235 0.0681818181818182
GO:BP GO:0034113 heterotypic cell-cell adhesion 0.00605959928275653 62 49 3 0.0612244897959184 0.0483870967741935
GO:BP GO:0042116 macrophage activation 0.00628470798031975 110 114 5 0.043859649122807 0.0454545454545455
GO:BP GO:0019218 regulation of steroid metabolic process 0.00641761981348277 130 97 5 0.0515463917525773 0.0384615384615385
GO:BP GO:0055082 cellular chemical homeostasis 0.0064368202048201 841 112 14 0.125 0.0166468489892985
GO:BP GO:0032103 positive regulation of response to external stimulus 0.0064368202048201 513 15 4 0.266666666666667 0.00779727095516569
GO:BP GO:0071219 cellular response to molecule of bacterial origin 0.0064368202048201 214 124 7 0.0564516129032258 0.0327102803738318
GO:BP GO:0032411 positive regulation of transporter activity 0.00659028319414306 118 108 5 0.0462962962962963 0.0423728813559322
GO:BP GO:0002274 myeloid leukocyte activation 0.00660772606068291 667 125 13 0.104 0.0194902548725637
GO:BP GO:0050798 activated T cell proliferation 0.00668741926407664 49 65 3 0.0461538461538462 0.0612244897959184
GO:BP GO:0002715 regulation of natural killer cell mediated immunity 0.00671965224862103 45 71 3 0.0422535211267606 0.0666666666666667
GO:BP GO:0042092 type 2 immune response 0.00680460400919484 37 87 3 0.0344827586206897 0.0810810810810811
GO:BP GO:0007160 cell-matrix adhesion 0.00700692295165729 235 84 6 0.0714285714285714 0.025531914893617
GO:BP GO:0045595 regulation of cell differentiation 0.00708628772007539 1679 3 3 1 0.00178677784395473
GO:BP GO:0010941 regulation of cell death 0.00743121692486568 1720 71 16 0.225352112676056 0.00930232558139535
GO:BP GO:0030073 insulin secretion 0.00758213980722128 218 16 3 0.1875 0.0137614678899083
GO:BP GO:0090276 regulation of peptide hormone secretion 0.00782576717437277 221 16 3 0.1875 0.0135746606334842
GO:BP GO:0051674 localization of cell 0.00798521996728884 1828 114 23 0.201754385964912 0.012582056892779
GO:BP GO:0048870 cell motility 0.00798521996728884 1828 114 23 0.201754385964912 0.012582056892779
GO:BP GO:0030003 cellular cation homeostasis 0.00809835273448314 673 112 12 0.107142857142857 0.0178306092124814
GO:BP GO:0002576 platelet degranulation 0.00820759065816694 126 28 3 0.107142857142857 0.0238095238095238
GO:BP GO:0098754 detoxification 0.00821104608746027 134 59 4 0.0677966101694915 0.0298507462686567
GO:BP GO:0048261 negative regulation of receptor-mediated endocytosis 0.00833126882422181 35 101 3 0.0297029702970297 0.0857142857142857
GO:BP GO:0050727 regulation of inflammatory response 0.00849303593876179 381 10 3 0.3 0.0078740157480315
GO:BP GO:0071248 cellular response to metal ion 0.00871483954318517 192 108 6 0.0555555555555556 0.03125
GO:BP GO:0008219 cell death 0.00871483954318517 2292 71 19 0.267605633802817 0.00828970331588133
GO:BP GO:0007229 integrin-mediated signaling pathway 0.00901744979555168 111 33 3 0.0909090909090909 0.027027027027027
GO:BP GO:0008202 steroid metabolic process 0.00909659082980449 342 109 8 0.073394495412844 0.0233918128654971
GO:BP GO:0006873 cellular ion homeostasis 0.00927793576192867 687 112 12 0.107142857142857 0.0174672489082969
GO:BP GO:0006875 cellular metal ion homeostasis 0.00927822336693335 593 112 11 0.0982142857142857 0.0185497470489039
GO:BP GO:0034612 response to tumor necrosis factor 0.0094460718303744 331 88 7 0.0795454545454545 0.0211480362537764
GO:BP GO:0002718 regulation of cytokine production involved in immune response 0.0096994912287636 85 99 4 0.0404040404040404 0.0470588235294118
GO:BP GO:0043523 regulation of neuron apoptotic process 0.0096994912287636 216 67 5 0.0746268656716418 0.0231481481481481
GO:BP GO:0032101 regulation of response to external stimulus 0.0096994912287636 1051 15 5 0.333333333333333 0.00475737392959087
GO:BP GO:0071216 cellular response to biotic stimulus 0.0100502809970742 238 124 7 0.0564516129032258 0.0294117647058824
GO:BP GO:0045596 negative regulation of cell differentiation 0.0106212586210681 697 113 12 0.106194690265487 0.0172166427546628
GO:BP GO:0015914 phospholipid transport 0.0108892115894994 94 93 4 0.043010752688172 0.0425531914893617
GO:BP GO:0033619 membrane protein proteolysis 0.0110803010081251 61 66 3 0.0454545454545455 0.0491803278688525
GO:BP GO:0031349 positive regulation of defense response 0.0110803010081251 362 42 5 0.119047619047619 0.0138121546961326
GO:BP GO:0030072 peptide hormone secretion 0.0110803010081251 260 16 3 0.1875 0.0115384615384615
GO:BP GO:0080134 regulation of response to stress 0.0111464957507766 1443 17 6 0.352941176470588 0.00415800415800416
GO:BP GO:0046165 alcohol biosynthetic process 0.0119398787093333 158 97 5 0.0515463917525773 0.0316455696202532
GO:BP GO:0040011 locomotion 0.0120813872930214 2028 114 24 0.210526315789474 0.0118343195266272
GO:BP GO:0046883 regulation of hormone secretion 0.0122858688219173 275 16 3 0.1875 0.0109090909090909
GO:BP GO:0015031 protein transport 0.0123692892087882 1929 18 7 0.388888888888889 0.00362882322446864
GO:BP GO:0097352 autophagosome maturation 0.0125215325264734 41 105 3 0.0285714285714286 0.0731707317073171
GO:BP GO:0045732 positive regulation of protein catabolic process 0.0125307139336761 237 97 6 0.0618556701030928 0.0253164556962025
GO:BP GO:0002367 cytokine production involved in immune response 0.0127105437184781 94 99 4 0.0404040404040404 0.0425531914893617
GO:BP GO:1903532 positive regulation of secretion by cell 0.0131429278436175 285 16 3 0.1875 0.0105263157894737
GO:BP GO:0030154 cell differentiation 0.0131429278436175 4350 79 31 0.392405063291139 0.0071264367816092
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.0132479808602444 1227 125 18 0.144 0.0146699266503667
GO:BP GO:0034767 positive regulation of ion transmembrane transport 0.0133627527595506 217 108 6 0.0555555555555556 0.0276497695852535
GO:BP GO:0034764 positive regulation of transmembrane transport 0.0133627527595506 217 108 6 0.0555555555555556 0.0276497695852535
GO:BP GO:0015833 peptide transport 0.0133724370463354 1971 18 7 0.388888888888889 0.00355149670218163
GO:BP GO:0097305 response to alcohol 0.0135890618792358 255 125 7 0.056 0.0274509803921569
GO:BP GO:0007257 activation of JUN kinase activity 0.0135890618792358 41 110 3 0.0272727272727273 0.0731707317073171
GO:BP GO:0006915 apoptotic process 0.0138373437245966 1990 67 16 0.238805970149254 0.00804020100502513
GO:BP GO:1903792 negative regulation of anion transport 0.0138373437245966 235 101 6 0.0594059405940594 0.025531914893617
GO:BP GO:0050708 regulation of protein secretion 0.0138802907853799 295 16 3 0.1875 0.0101694915254237
GO:BP GO:0071241 cellular response to inorganic substance 0.0138802907853799 220 108 6 0.0555555555555556 0.0272727272727273
GO:BP GO:0071396 cellular response to lipid 0.0140066907850878 578 124 11 0.0887096774193548 0.0190311418685121
GO:BP GO:0051592 response to calcium ion 0.014187501868642 151 108 5 0.0462962962962963 0.033112582781457
GO:BP GO:0002228 natural killer cell mediated immunity 0.0141959767861001 65 71 3 0.0422535211267606 0.0461538461538462
GO:BP GO:0002455 humoral immune response mediated by circulating immunoglobulin 0.0142122871116005 156 63 4 0.0634920634920635 0.0256410256410256
GO:BP GO:0042886 amide transport 0.0142429914518762 2007 18 7 0.388888888888889 0.00348779272546089
GO:BP GO:0046903 secretion 0.0144108622127029 1501 36 9 0.25 0.00599600266489007
GO:BP GO:0002702 positive regulation of production of molecular mediator of immune response 0.0145991633134341 100 99 4 0.0404040404040404 0.04
GO:BP GO:0002831 regulation of response to biotic stimulus 0.0146846733262496 415 124 9 0.0725806451612903 0.0216867469879518
GO:BP GO:0006694 steroid biosynthetic process 0.0149270747721947 196 85 5 0.0588235294117647 0.0255102040816327
GO:BP GO:0055080 cation homeostasis 0.0149270747721947 750 112 12 0.107142857142857 0.016
GO:BP GO:0045184 establishment of protein localization 0.0149270747721947 2035 18 7 0.388888888888889 0.00343980343980344
GO:BP GO:0051402 neuron apoptotic process 0.0149270747721947 250 67 5 0.0746268656716418 0.02
GO:BP GO:0071356 cellular response to tumor necrosis factor 0.0149270747721947 306 55 5 0.0909090909090909 0.0163398692810458
GO:BP GO:0002526 acute inflammatory response 0.0149597817707883 114 42 3 0.0714285714285714 0.0263157894736842
GO:BP GO:0022607 cellular component assembly 0.0152867882444113 3010 10 6 0.6 0.00199335548172757
GO:BP GO:0051047 positive regulation of secretion 0.0154496608183045 314 16 3 0.1875 0.00955414012738853
GO:BP GO:1901617 organic hydroxy compound biosynthetic process 0.0154496608183045 254 97 6 0.0618556701030928 0.0236220472440945
GO:BP GO:0048869 cellular developmental process 0.0155785862992376 4428 79 31 0.392405063291139 0.00700090334236676
GO:BP GO:0046879 hormone secretion 0.0156800771431968 317 16 3 0.1875 0.00946372239747634
GO:BP GO:0034204 lipid translocation 0.0159607269496953 51 97 3 0.0309278350515464 0.0588235294117647
GO:BP GO:0051050 positive regulation of transport 0.0161137431047304 923 81 11 0.135802469135802 0.0119176598049837
GO:BP GO:0098771 inorganic ion homeostasis 0.0161137431047304 761 112 12 0.107142857142857 0.0157687253613666
GO:BP GO:0031295 T cell costimulation 0.0165254152128276 58 87 3 0.0344827586206897 0.0517241379310345
GO:BP GO:0009914 hormone transport 0.0165714286234392 327 16 3 0.1875 0.00917431192660551
GO:BP GO:0071702 organic substance transport 0.016716340110682 2766 108 28 0.259259259259259 0.0101229211858279
GO:BP GO:0051222 positive regulation of protein transport 0.016768630440648 329 16 3 0.1875 0.00911854103343465
GO:BP GO:0055065 metal ion homeostasis 0.0168315413244795 667 112 11 0.0982142857142857 0.0164917541229385
GO:BP GO:0046394 carboxylic acid biosynthetic process 0.0168523930278606 330 16 3 0.1875 0.00909090909090909
GO:BP GO:0044283 small molecule biosynthetic process 0.0169369221996437 704 16 4 0.25 0.00568181818181818
GO:BP GO:0150076 neuroinflammatory response 0.0171620958022873 51 101 3 0.0297029702970297 0.0588235294117647
GO:BP GO:0072503 cellular divalent inorganic cation homeostasis 0.0172357692361722 497 108 9 0.0833333333333333 0.0181086519114688
GO:BP GO:0051602 response to electrical stimulus 0.0172634056074274 45 115 3 0.0260869565217391 0.0666666666666667
GO:BP GO:0050793 regulation of developmental process 0.0175448553085491 2605 3 3 1 0.00115163147792706
GO:BP GO:0031294 lymphocyte costimulation 0.0176833883080799 60 87 3 0.0344827586206897 0.05
GO:BP GO:0016053 organic acid biosynthetic process 0.0176833883080799 338 16 3 0.1875 0.00887573964497041
GO:BP GO:0045088 regulation of innate immune response 0.018194862203745 309 84 6 0.0714285714285714 0.0194174757281553
GO:BP GO:1904951 positive regulation of establishment of protein localization 0.0183815667416427 345 16 3 0.1875 0.00869565217391304
GO:BP GO:0045806 negative regulation of endocytosis 0.0183815667416427 53 101 3 0.0297029702970297 0.0566037735849057
GO:BP GO:0048522 positive regulation of cellular process 0.0183815667416427 5757 5 5 1 0.000868507903421921
GO:BP GO:0048731 system development 0.018424126767757 5052 118 47 0.398305084745763 0.00930324623911322
GO:BP GO:0097035 regulation of membrane lipid distribution 0.019191490073897 57 97 3 0.0309278350515464 0.0526315789473684
GO:BP GO:0044085 cellular component biogenesis 0.019191490073897 3257 16 8 0.5 0.00245624808105619
GO:BP GO:0048878 chemical homeostasis 0.019562972944518 1229 112 16 0.142857142857143 0.0130187144019528
GO:BP GO:0072507 divalent inorganic cation homeostasis 0.0199992057621282 516 108 9 0.0833333333333333 0.0174418604651163
GO:BP GO:0016125 sterol metabolic process 0.0201042901270099 171 109 5 0.0458715596330275 0.0292397660818713
GO:BP GO:0043270 positive regulation of ion transport 0.0201283387144237 694 81 9 0.111111111111111 0.0129682997118156
GO:BP GO:0070839 metal ion export 0.0203155908553442 51 112 3 0.0267857142857143 0.0588235294117647
GO:BP GO:0040013 negative regulation of locomotion 0.0203155908553442 401 114 8 0.0701754385964912 0.0199501246882793
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.0203886918067741 3483 7 5 0.714285714285714 0.00143554407120299
GO:BP GO:0072676 lymphocyte migration 0.0204061128867496 117 49 3 0.0612244897959184 0.0256410256410256
GO:BP GO:0045807 positive regulation of endocytosis 0.0205007510060964 101 115 4 0.0347826086956522 0.0396039603960396
GO:BP GO:0042981 regulation of apoptotic process 0.0206615082989586 1549 67 13 0.194029850746269 0.00839251129761136
GO:BP GO:0010812 negative regulation of cell-substrate adhesion 0.0209056921382642 69 84 3 0.0357142857142857 0.0434782608695652
GO:BP GO:0032102 negative regulation of response to external stimulus 0.0213120108412636 406 114 8 0.0701754385964912 0.0197044334975369
GO:BP GO:0050801 ion homeostasis 0.021645115158599 808 112 12 0.107142857142857 0.0148514851485149
GO:BP GO:0098869 cellular oxidant detoxification 0.021645115158599 100 59 3 0.0508474576271186 0.03
GO:BP GO:0050890 cognition 0.0218809521317079 298 65 5 0.0769230769230769 0.0167785234899329
GO:BP GO:0012501 programmed cell death 0.0218809521317079 2143 67 16 0.238805970149254 0.00746616892207186
GO:BP GO:0009306 protein secretion 0.0218809521317079 384 16 3 0.1875 0.0078125
GO:BP GO:0035592 establishment of protein localization to extracellular region 0.0220072930497897 385 16 3 0.1875 0.00779220779220779
GO:BP GO:0006928 movement of cell or subcellular component 0.0220122934594893 2311 114 25 0.219298245614035 0.0108178277801817
GO:BP GO:0042592 homeostatic process 0.0227846608237139 1981 112 22 0.196428571428571 0.01110550227158
GO:BP GO:0032940 secretion by cell 0.0228525122844569 1364 36 8 0.222222222222222 0.00586510263929619
GO:BP GO:0071692 protein localization to extracellular region 0.0228525122844569 392 16 3 0.1875 0.0076530612244898
GO:BP GO:0030001 metal ion transport 0.0228799647002695 514 112 9 0.0803571428571429 0.0175097276264591
GO:BP GO:0050803 regulation of synapse structure or activity 0.0228799647002695 223 88 5 0.0568181818181818 0.0224215246636771
GO:BP GO:0048513 animal organ development 0.0228799647002695 3672 125 38 0.304 0.0103485838779956
GO:BP GO:0051179 localization 0.0228799647002695 6901 115 58 0.504347826086956 0.008404579046515
GO:BP GO:0034446 substrate adhesion-dependent cell spreading 0.0229556600232766 109 56 3 0.0535714285714286 0.0275229357798165
GO:BP GO:0032787 monocarboxylic acid metabolic process 0.0232222593382675 658 10 3 0.3 0.00455927051671732
GO:BP GO:0050789 regulation of biological process 0.0232252775653889 12091 122 95 0.778688524590164 0.00785708378132495
GO:BP GO:0043067 regulation of programmed cell death 0.0233309330976847 1582 67 13 0.194029850746269 0.00821744627054362
GO:BP GO:1904645 response to amyloid-beta 0.0233314550687765 55 112 3 0.0267857142857143 0.0545454545454545
GO:BP GO:0050808 synapse organization 0.0234258224290767 428 88 7 0.0795454545454545 0.0163551401869159
GO:BP GO:0021700 developmental maturation 0.0236161082437792 275 103 6 0.058252427184466 0.0218181818181818
GO:BP GO:0042157 lipoprotein metabolic process 0.0237812723454996 136 91 4 0.043956043956044 0.0294117647058824
GO:BP GO:0022411 cellular component disassembly 0.0238475984031884 571 84 8 0.0952380952380952 0.0140105078809107
GO:BP GO:0071705 nitrogen compound transport 0.0238475984031884 2322 18 7 0.388888888888889 0.00301464254952627
GO:BP GO:0019217 regulation of fatty acid metabolic process 0.0238475984031884 105 118 4 0.0338983050847458 0.0380952380952381
GO:BP GO:0060401 cytosolic calcium ion transport 0.0245241373949533 186 108 5 0.0462962962962963 0.0268817204301075
GO:BP GO:0006820 anion transport 0.0247031588059265 2889 108 28 0.259259259259259 0.00969193492557979
GO:BP GO:0060326 cell chemotaxis 0.0249853455373966 310 21 3 0.142857142857143 0.00967741935483871
GO:BP GO:0015748 organophosphate ester transport 0.0251695856530622 136 93 4 0.043010752688172 0.0294117647058824
GO:BP GO:0034394 protein localization to cell surface 0.025275004873049 66 97 3 0.0309278350515464 0.0454545454545455
GO:BP GO:0033344 cholesterol efflux 0.025275004873049 66 97 3 0.0309278350515464 0.0454545454545455
GO:BP GO:0006898 receptor-mediated endocytosis 0.0253595132314351 333 115 7 0.0608695652173913 0.021021021021021
GO:BP GO:1904062 regulation of cation transmembrane transport 0.0257856821113896 360 81 6 0.0740740740740741 0.0166666666666667
GO:BP GO:0065007 biological regulation 0.0257857859613892 12809 97 80 0.824742268041237 0.00624560855648372
GO:BP GO:0097190 apoptotic signaling pathway 0.0258966932197054 600 65 7 0.107692307692308 0.0116666666666667
GO:BP GO:0140352 export from cell 0.0259688492274768 1418 120 18 0.15 0.0126939351198872
GO:BP GO:0009893 positive regulation of metabolic process 0.0261538053978483 3783 7 5 0.714285714285714 0.00132170235263019
GO:BP GO:1903779 regulation of cardiac conduction 0.0266397365089249 59 112 3 0.0267857142857143 0.0508474576271186
GO:BP GO:0002833 positive regulation of response to biotic stimulus 0.0270205323960949 250 27 3 0.111111111111111 0.012
GO:BP GO:0008203 cholesterol metabolic process 0.0270331901030526 154 85 4 0.0470588235294118 0.025974025974026
GO:BP GO:1990748 cellular detoxification 0.0270331901030526 113 59 3 0.0508474576271186 0.0265486725663717
GO:BP GO:0034330 cell junction organization 0.0271161324343528 722 69 8 0.115942028985507 0.0110803324099723
GO:BP GO:0042113 B cell activation 0.0272041216029382 330 90 6 0.0666666666666667 0.0181818181818182
GO:BP GO:0019216 regulation of lipid metabolic process 0.0275376356007415 419 118 8 0.0677966101694915 0.0190930787589499
GO:BP GO:0030004 cellular monovalent inorganic cation homeostasis 0.0275939994453205 118 112 4 0.0357142857142857 0.0338983050847458
GO:BP GO:0008610 lipid biosynthetic process 0.0277234785681157 740 97 10 0.103092783505155 0.0135135135135135
GO:BP GO:0006874 cellular calcium ion homeostasis 0.0277870290406821 460 108 8 0.0740740740740741 0.0173913043478261
GO:BP GO:0033036 macromolecule localization 0.028595586006514 3218 108 30 0.277777777777778 0.00932256059664388
GO:BP GO:0050900 leukocyte migration 0.0286642769549274 511 27 4 0.148148148148148 0.00782778864970646
GO:BP GO:0140115 export across plasma membrane 0.0290595012302473 62 112 3 0.0267857142857143 0.0483870967741935
GO:BP GO:0051453 regulation of intracellular pH 0.0290660114126227 89 78 3 0.0384615384615385 0.0337078651685393
GO:BP GO:0032374 regulation of cholesterol transport 0.0293259223658038 72 97 3 0.0309278350515464 0.0416666666666667
GO:BP GO:0032371 regulation of sterol transport 0.0293259223658038 72 97 3 0.0309278350515464 0.0416666666666667
GO:BP GO:0051093 negative regulation of developmental process 0.0296432112565977 977 99 12 0.121212121212121 0.0122824974411464
GO:BP GO:0006811 ion transport 0.0296432112565977 3661 112 34 0.303571428571429 0.00928708003277793
GO:BP GO:0097237 cellular response to toxic substance 0.0299626842606275 120 59 3 0.0508474576271186 0.025
GO:BP GO:0055074 calcium ion homeostasis 0.0307448021329382 472 108 8 0.0740740740740741 0.0169491525423729
GO:BP GO:1902652 secondary alcohol metabolic process 0.0311438686473231 164 85 4 0.0470588235294118 0.024390243902439
GO:BP GO:0045862 positive regulation of proteolysis 0.0312986417738556 378 108 7 0.0648148148148148 0.0185185185185185
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 0.0328540301235008 177 42 3 0.0714285714285714 0.0169491525423729
GO:BP GO:0050922 negative regulation of chemotaxis 0.0328701183883566 65 114 3 0.0263157894736842 0.0461538461538462
GO:BP GO:0030641 regulation of cellular pH 0.0328896939848645 95 78 3 0.0384615384615385 0.0315789473684211
GO:BP GO:0000904 cell morphogenesis involved in differentiation 0.032979599082137 749 70 8 0.114285714285714 0.0106809078771696
GO:BP GO:0009636 response to toxic substance 0.032979599082137 243 59 4 0.0677966101694915 0.0164609053497942
GO:BP GO:0006887 exocytosis 0.0333041418472621 904 36 6 0.166666666666667 0.00663716814159292
GO:BP GO:0008104 protein localization 0.0339912126949694 2770 29 10 0.344827586206897 0.0036101083032491
GO:BP GO:0034381 plasma lipoprotein particle clearance 0.0343537105490253 70 109 3 0.0275229357798165 0.0428571428571429
GO:BP GO:0072678 T cell migration 0.0343636631366226 67 114 3 0.0263157894736842 0.0447761194029851
GO:BP GO:0050810 regulation of steroid biosynthetic process 0.0344387604136254 97 79 3 0.0379746835443038 0.0309278350515464
GO:BP GO:0051649 establishment of localization in cell 0.0344387604136254 2813 120 29 0.241666666666667 0.0103092783505155
GO:BP GO:0023061 signal release 0.0344387604136254 496 16 3 0.1875 0.00604838709677419
GO:BP GO:0002700 regulation of production of molecular mediator of immune response 0.0344843405179383 148 99 4 0.0404040404040404 0.027027027027027
GO:BP GO:0098662 inorganic cation transmembrane transport 0.0345114919334697 794 81 9 0.111111111111111 0.0113350125944584
GO:BP GO:0050794 regulation of cellular process 0.0345832993924539 11473 77 59 0.766233766233766 0.0051425084982132
GO:BP GO:1903793 positive regulation of anion transport 0.0352997387749035 504 16 3 0.1875 0.00595238095238095
GO:BP GO:0043507 positive regulation of JUN kinase activity 0.0353712816152864 71 110 3 0.0272727272727273 0.0422535211267606
GO:BP GO:1901224 positive regulation of NIK/NF-kappaB signaling 0.035384901186807 68 115 3 0.0260869565217391 0.0441176470588235
GO:BP GO:1903364 positive regulation of cellular protein catabolic process 0.035851710467507 154 97 4 0.0412371134020619 0.025974025974026
GO:BP GO:0042058 regulation of epidermal growth factor receptor signaling pathway 0.0361957562448578 90 88 3 0.0340909090909091 0.0333333333333333
GO:BP GO:0006885 regulation of pH 0.0370665400547386 103 78 3 0.0384615384615385 0.029126213592233
GO:BP GO:0034622 cellular protein-containing complex assembly 0.0373672830604618 1107 8 3 0.375 0.002710027100271
GO:BP GO:2001259 positive regulation of cation channel activity 0.0386281371487504 76 108 3 0.0277777777777778 0.0394736842105263
GO:BP GO:0019752 carboxylic acid metabolic process 0.0390281261994663 1024 16 4 0.25 0.00390625
GO:BP GO:0010817 regulation of hormone levels 0.0392857614123295 536 16 3 0.1875 0.00559701492537313
GO:BP GO:0051651 maintenance of location in cell 0.0392857614123295 223 108 5 0.0462962962962963 0.0224215246636771
GO:BP GO:0009896 positive regulation of catabolic process 0.0396338917510164 464 118 8 0.0677966101694915 0.0172413793103448
GO:BP GO:0008285 negative regulation of cell population proliferation 0.0397084892917834 790 114 11 0.0964912280701754 0.0139240506329114
GO:BP GO:0032501 multicellular organismal process 0.0414269181713989 7946 16 12 0.75 0.00151019380820539
GO:BP GO:1901184 regulation of ERBB signaling pathway 0.0414269181713989 97 88 3 0.0340909090909091 0.0309278350515464
GO:BP GO:0043436 oxoacid metabolic process 0.0415243521587288 1057 16 4 0.25 0.00378429517502365
GO:BP GO:0031668 cellular response to extracellular stimulus 0.0417852159286884 248 35 3 0.0857142857142857 0.0120967741935484
GO:BP GO:0040008 regulation of growth 0.042196946629166 681 99 9 0.0909090909090909 0.013215859030837
GO:BP GO:0031348 negative regulation of defense response 0.0422841147750566 246 101 5 0.0495049504950495 0.0203252032520325
GO:BP GO:0070588 calcium ion transmembrane transport 0.042543930557383 320 108 6 0.0555555555555556 0.01875
GO:BP GO:0032368 regulation of lipid transport 0.0428430579777599 167 97 4 0.0412371134020619 0.0239520958083832
GO:BP GO:0007163 establishment or maintenance of cell polarity 0.043146998773572 220 74 4 0.0540540540540541 0.0181818181818182
GO:BP GO:0032715 negative regulation of interleukin-6 production 0.0441422840098288 73 121 3 0.0247933884297521 0.0410958904109589
GO:BP GO:0045926 negative regulation of growth 0.0443604663360202 255 99 5 0.0505050505050505 0.0196078431372549
GO:BP GO:0048468 cell development 0.0443604663360202 2100 70 15 0.214285714285714 0.00714285714285714
GO:BP GO:0006082 organic acid metabolic process 0.0447276867531488 1090 16 4 0.25 0.0036697247706422
GO:BP GO:0006958 complement activation, classical pathway 0.0448037870697687 142 63 3 0.0476190476190476 0.0211267605633803
GO:BP GO:0050806 positive regulation of synaptic transmission 0.0448391361128158 152 59 3 0.0508474576271186 0.0197368421052632
GO:BP GO:0043271 negative regulation of ion transport 0.0449053417418584 349 101 6 0.0594059405940594 0.0171919770773639
GO:BP GO:0051223 regulation of protein transport 0.0456569512357532 586 16 3 0.1875 0.00511945392491468
GO:BP GO:1903530 regulation of secretion by cell 0.0456794795051926 588 16 3 0.1875 0.00510204081632653
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 0.0468209503006926 294 88 5 0.0568181818181818 0.0170068027210884
GO:BP GO:0060191 regulation of lipase activity 0.0468675748121115 101 91 3 0.032967032967033 0.0297029702970297
GO:BP GO:0031331 positive regulation of cellular catabolic process 0.0472471145023844 393 118 7 0.0593220338983051 0.0178117048346056
GO:BP GO:0071674 mononuclear cell migration 0.0482889929380558 191 49 3 0.0612244897959184 0.0157068062827225
GO:BP GO:0000187 activation of MAPK activity 0.0486107266951545 156 110 4 0.0363636363636364 0.0256410256410256
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.0486301364392462 236 40 3 0.075 0.0127118644067797
GO:BP GO:0070201 regulation of establishment of protein localization 0.0493002326132685 611 16 3 0.1875 0.00490998363338789
GO:BP GO:0006816 calcium ion transport 0.0495495683367803 436 108 7 0.0648148148148148 0.0160550458715596
GO:BP GO:0016192 vesicle-mediated transport 0.0497525001978352 2180 120 23 0.191666666666667 0.0105504587155963
GO:BP GO:0006812 cation transport 0.0498008143638658 1197 112 14 0.125 0.0116959064327485
GO:CC GO:0042613 MHC class II protein complex 8.46343460101562e-22 16 20 9 0.45 0.5625
GO:CC GO:0042611 MHC protein complex 4.81634243565764e-20 24 20 9 0.45 0.375
GO:CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 1.21630000147933e-13 25 11 6 0.545454545454545 0.24
GO:CC GO:0098553 lumenal side of endoplasmic reticulum membrane 1.21630000147933e-13 25 11 6 0.545454545454545 0.24
GO:CC GO:0098576 lumenal side of membrane 6.0742983478082e-13 33 11 6 0.545454545454545 0.181818181818182
GO:CC GO:0030669 clathrin-coated endocytic vesicle membrane 8.89594478888784e-13 36 11 6 0.545454545454545 0.166666666666667
GO:CC GO:0045334 clathrin-coated endocytic vesicle 8.52340753969918e-12 54 5 5 1 0.0925925925925926
GO:CC GO:0012507 ER to Golgi transport vesicle membrane 9.87423264864923e-12 57 5 5 1 0.087719298245614
GO:CC GO:0030665 clathrin-coated vesicle membrane 3.34266048123548e-11 114 14 7 0.5 0.0614035087719298
GO:CC GO:0005765 lysosomal membrane 5.08719575890733e-11 383 20 10 0.5 0.0261096605744125
GO:CC GO:0005773 vacuole 5.08719575890733e-11 810 123 27 0.219512195121951 0.0333333333333333
GO:CC GO:0098852 lytic vacuole membrane 5.08719575890733e-11 383 20 10 0.5 0.0261096605744125
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 6.37804649239961e-11 90 5 5 1 0.0555555555555556
GO:CC GO:0032588 trans-Golgi network membrane 7.3969492062154e-11 94 5 5 1 0.0531914893617021
GO:CC GO:0005774 vacuolar membrane 8.44639446258763e-11 441 105 19 0.180952380952381 0.0430839002267574
GO:CC GO:0098797 plasma membrane protein complex 8.44639446258763e-11 694 14 10 0.714285714285714 0.0144092219020173
GO:CC GO:0005764 lysosome 8.44639446258763e-11 712 123 25 0.203252032520325 0.0351123595505618
GO:CC GO:0000323 lytic vacuole 8.44639446258763e-11 712 123 25 0.203252032520325 0.0351123595505618
GO:CC GO:0010008 endosome membrane 1.40744215162552e-10 505 120 21 0.175 0.0415841584158416
GO:CC GO:0009986 cell surface 3.2100658693208e-10 899 53 18 0.339622641509434 0.0200222469410456
GO:CC GO:0030662 coated vesicle membrane 3.26661108333285e-10 177 14 7 0.5 0.0395480225988701
GO:CC GO:0030136 clathrin-coated vesicle 5.74241004788137e-10 193 14 7 0.5 0.0362694300518135
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 6.24736757792238e-10 158 5 5 1 0.0316455696202532
GO:CC GO:0030666 endocytic vesicle membrane 6.24736757792238e-10 159 5 5 1 0.0314465408805031
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 7.45927522244392e-10 166 5 5 1 0.0301204819277108
GO:CC GO:0030658 transport vesicle membrane 2.2978720405646e-09 209 5 5 1 0.0239234449760766
GO:CC GO:0098552 side of membrane 2.38270010929465e-09 619 15 9 0.6 0.0145395799676898
GO:CC GO:0005802 trans-Golgi network 5.26699864352082e-09 250 5 5 1 0.02
GO:CC GO:0005768 endosome 5.69132175197335e-09 987 120 26 0.216666666666667 0.0263424518743668
GO:CC GO:0030135 coated vesicle 8.24967550917051e-09 295 14 7 0.5 0.023728813559322
GO:CC GO:0030139 endocytic vesicle 1.31668190744443e-08 306 5 5 1 0.0163398692810458
GO:CC GO:0031902 late endosome membrane 1.68281130884463e-08 140 120 11 0.0916666666666667 0.0785714285714286
GO:CC GO:0071944 cell periphery 1.96502639903611e-08 6169 94 59 0.627659574468085 0.00956394877613876
GO:CC GO:0098796 membrane protein complex 2.29994680316435e-08 1322 14 10 0.714285714285714 0.0075642965204236
GO:CC GO:0031410 cytoplasmic vesicle 3.3415694102454e-08 2424 105 37 0.352380952380952 0.0152640264026403
GO:CC GO:0031301 integral component of organelle membrane 3.3666607966173e-08 382 5 5 1 0.0130890052356021
GO:CC GO:0097708 intracellular vesicle 3.3666607966173e-08 2428 105 37 0.352380952380952 0.0152388797364086
GO:CC GO:0030133 transport vesicle 4.78527412319418e-08 414 5 5 1 0.0120772946859903
GO:CC GO:0031300 intrinsic component of organelle membrane 4.78527412319418e-08 413 5 5 1 0.0121065375302663
GO:CC GO:0005770 late endosome 7.94516105791664e-08 275 20 7 0.35 0.0254545454545455
GO:CC GO:0005886 plasma membrane 2.40793412959269e-07 5681 101 57 0.564356435643564 0.0100334448160535
GO:CC GO:0009897 external side of plasma membrane 2.40793412959269e-07 408 115 15 0.130434782608696 0.0367647058823529
GO:CC GO:0016020 membrane 2.40793412959269e-07 9838 99 78 0.787878787878788 0.0079284407399878
GO:CC GO:0098588 bounding membrane of organelle 2.4168285098623e-07 2158 120 36 0.3 0.0166821130676552
GO:CC GO:0031982 vesicle 5.84693152338611e-07 4055 105 47 0.447619047619048 0.0115906288532676
GO:CC GO:0000139 Golgi membrane 9.19111788139321e-07 771 5 5 1 0.00648508430609598
GO:CC GO:0030659 cytoplasmic vesicle membrane 9.47331067632513e-07 779 5 5 1 0.00641848523748395
GO:CC GO:0012506 vesicle membrane 1.05990746348025e-06 800 5 5 1 0.00625
GO:CC GO:0098791 Golgi apparatus subcompartment 1.72227617441996e-06 885 5 5 1 0.00564971751412429
GO:CC GO:0005789 endoplasmic reticulum membrane 4.98355999423574e-06 1117 11 7 0.636363636363636 0.0062667860340197
GO:CC GO:0098827 endoplasmic reticulum subcompartment 5.03653957152557e-06 1122 11 7 0.636363636363636 0.00623885918003565
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 5.47145507616076e-06 1139 11 7 0.636363636363636 0.00614574187884109
GO:CC GO:0005887 integral component of plasma membrane 8.57578189365252e-06 1645 101 25 0.247524752475248 0.0151975683890578
GO:CC GO:0005783 endoplasmic reticulum 1.05785860293201e-05 1982 17 10 0.588235294117647 0.00504540867810293
GO:CC GO:0031090 organelle membrane 1.19854762293245e-05 3612 120 45 0.375 0.0124584717607973
GO:CC GO:0016021 integral component of membrane 1.24043987901884e-05 5711 103 54 0.524271844660194 0.00945543687620382
GO:CC GO:0031226 intrinsic component of plasma membrane 1.90935140267291e-05 1726 101 25 0.247524752475248 0.0144843568945539
GO:CC GO:0012505 endomembrane system 2.86734181699539e-05 4640 108 48 0.444444444444444 0.0103448275862069
GO:CC GO:0031224 intrinsic component of membrane 2.92323217360358e-05 5868 103 54 0.524271844660194 0.00920245398773006
GO:CC GO:0005794 Golgi apparatus 2.93265610161943e-05 1623 5 5 1 0.00308071472581639
GO:CC GO:0031984 organelle subcompartment 4.49014555436225e-05 1773 5 5 1 0.00282007896221094
GO:CC GO:0070062 extracellular exosome 0.000111866903132593 2176 40 15 0.375 0.00689338235294118
GO:CC GO:1903561 extracellular vesicle 0.000173624824487553 2261 40 15 0.375 0.00663423264042459
GO:CC GO:0043230 extracellular organelle 0.000173624824487553 2263 40 15 0.375 0.0066283694211224
GO:CC GO:0005615 extracellular space 0.000173890509090551 3594 91 34 0.373626373626374 0.00946021146355036
GO:CC GO:0005576 extracellular region 0.000829134688850302 4567 91 38 0.417582417582418 0.00832056054302606
GO:CC GO:0098533 ATPase dependent transmembrane transport complex 0.000856415918818174 18 112 3 0.0267857142857143 0.166666666666667
GO:CC GO:0032991 protein-containing complex 0.00339750525872802 5548 6 6 1 0.00108147080028839
GO:CC GO:0030054 cell junction 0.00530850908157417 2105 74 18 0.243243243243243 0.00855106888361045
GO:CC GO:0005775 vacuolar lumen 0.00985673931418448 174 58 4 0.0689655172413793 0.0229885057471264
GO:CC GO:0043202 lysosomal lumen 0.0114347709574641 97 109 4 0.036697247706422 0.0412371134020619
GO:CC GO:0044297 cell body 0.013902820814672 592 114 10 0.087719298245614 0.0168918918918919
GO:CC GO:1904949 ATPase complex 0.0172786275132351 108 112 4 0.0357142857142857 0.037037037037037
GO:CC GO:0055037 recycling endosome 0.0174568947116229 188 105 5 0.0476190476190476 0.0265957446808511
GO:CC GO:0043025 neuronal cell body 0.0177755177220957 518 114 9 0.0789473684210526 0.0173745173745174
GO:CC GO:0070161 anchoring junction 0.0191574896028274 836 36 6 0.166666666666667 0.00717703349282297
GO:CC GO:0008021 synaptic vesicle 0.0214026216936244 209 101 5 0.0495049504950495 0.0239234449760766
GO:CC GO:0036477 somatodendritic compartment 0.0244391175058694 871 114 12 0.105263157894737 0.0137772675086108
GO:CC GO:0070382 exocytic vesicle 0.0296632912200472 229 101 5 0.0495049504950495 0.0218340611353712
GO:CC GO:0005925 focal adhesion 0.0303342593788568 420 56 5 0.0892857142857143 0.0119047619047619
GO:CC GO:0030055 cell-substrate junction 0.0317828833913403 427 56 5 0.0892857142857143 0.0117096018735363
GO:CC GO:0055038 recycling endosome membrane 0.0364872370118248 84 101 3 0.0297029702970297 0.0357142857142857
GO:CC GO:0043235 receptor complex 0.0382349906760936 522 49 5 0.102040816326531 0.00957854406130268
GO:CC GO:0034451 centriolar satellite 0.0431132610542185 107 87 3 0.0344827586206897 0.0280373831775701
GO:CC GO:0098802 plasma membrane signaling receptor complex 0.0467961347738788 300 33 3 0.0909090909090909 0.01
GO:MF GO:0023026 MHC class II protein complex binding 4.11966482095426e-10 17 90 7 0.0777777777777778 0.411764705882353
GO:MF GO:0042605 peptide antigen binding 8.00039314135701e-10 30 11 5 0.454545454545455 0.166666666666667
GO:MF GO:0023023 MHC protein complex binding 3.29003426652294e-09 25 90 7 0.0777777777777778 0.28
GO:MF GO:0032395 MHC class II receptor activity 2.3880928721947e-08 8 4 3 0.75 0.375
GO:MF GO:0042277 peptide binding 1.20552128570931e-07 314 5 5 1 0.0159235668789809
GO:MF GO:0003823 antigen binding 1.45854190749979e-07 163 15 6 0.4 0.0368098159509202
GO:MF GO:0140375 immune receptor activity 1.62602509420884e-07 133 4 4 1 0.0300751879699248
GO:MF GO:0033218 amide binding 2.21230277461066e-07 389 5 5 1 0.012853470437018
GO:MF GO:0042608 T cell receptor binding 2.83633678993611e-06 11 14 3 0.214285714285714 0.272727272727273
GO:MF GO:0044877 protein-containing complex binding 0.000315315250503702 1287 105 21 0.2 0.0163170163170163
GO:MF GO:0005102 signaling receptor binding 0.000317352193342094 1672 42 14 0.333333333333333 0.00837320574162679
GO:MF GO:0004888 transmembrane signaling receptor activity 0.000655065912491426 1269 4 4 1 0.00315208825847124
GO:MF GO:0038023 signaling receptor activity 0.00100780750059859 1458 4 4 1 0.00274348422496571
GO:MF GO:0060089 molecular transducer activity 0.00100780750059859 1458 4 4 1 0.00274348422496571
GO:MF GO:0032813 tumor necrosis factor receptor superfamily binding 0.00213313777145317 49 88 4 0.0454545454545455 0.0816326530612245
GO:MF GO:0005123 death receptor binding 0.00251746422331292 20 88 3 0.0340909090909091 0.15
GO:MF GO:0001540 amyloid-beta binding 0.0030213142274251 83 59 4 0.0677966101694915 0.0481927710843374
GO:MF GO:0005544 calcium-dependent phospholipid binding 0.00390514701172007 54 39 3 0.0769230769230769 0.0555555555555556
GO:MF GO:0008289 lipid binding 0.0141634102442366 776 115 13 0.11304347826087 0.0167525773195876
GO:MF GO:0008047 enzyme activator activity 0.0167210036160373 540 91 9 0.0989010989010989 0.0166666666666667
GO:MF GO:0005178 integrin binding 0.0174246900377791 147 28 3 0.107142857142857 0.0204081632653061
GO:MF GO:0048487 beta-tubulin binding 0.0176398178506251 41 101 3 0.0297029702970297 0.0731707317073171
GO:MF GO:0016209 antioxidant activity 0.0275192121846961 87 59 3 0.0508474576271186 0.0344827586206897
GO:MF GO:0005543 phospholipid binding 0.0311281677262383 454 101 8 0.0792079207920792 0.0176211453744493
GO:MF GO:0098772 molecular function regulator 0.040925115673455 2363 99 22 0.222222222222222 0.00931019889970377
HP HP:0001701 Pericarditis 0.00182771546202353 34 5 3 0.6 0.0882352941176471
HP HP:0100749 Chest pain 0.00182771546202353 93 6 4 0.666666666666667 0.043010752688172
HP HP:0011227 Elevated C-reactive protein level 0.00182771546202353 51 5 3 0.6 0.0588235294117647
HP HP:0002113 Pulmonary infiltrates 0.00182771546202353 53 5 3 0.6 0.0566037735849057
HP HP:0045073 Serositis 0.00182771546202353 40 5 3 0.6 0.075
HP HP:0002524 Cataplexy 0.00182771546202353 12 42 4 0.0952380952380952 0.333333333333333
HP HP:0000988 Skin rash 0.00182771546202353 114 7 4 0.571428571428571 0.0350877192982456
HP HP:0032436 Abnormal C-reactive protein level 0.00182771546202353 52 5 3 0.6 0.0576923076923077
HP HP:0003565 Elevated erythrocyte sedimentation rate 0.00182771546202353 48 5 3 0.6 0.0625
HP HP:0025021 Abnormal erythrocyte sedimentation rate 0.00182771546202353 49 5 3 0.6 0.0612244897959184
HP HP:0012735 Cough 0.00182771546202353 128 6 4 0.666666666666667 0.03125
HP HP:0011122 Abnormality of skin physiology 0.00182771546202353 430 7 6 0.857142857142857 0.013953488372093
HP HP:0000873 Diabetes insipidus 0.00205664241316691 57 5 3 0.6 0.0526315789473684
HP HP:0002105 Hemoptysis 0.00205664241316691 59 5 3 0.6 0.0508474576271186
HP HP:0033331 Acute phase response 0.00232233421325449 65 5 3 0.6 0.0461538461538462
HP HP:0002960 Autoimmunity 0.00232233421325449 170 6 4 0.666666666666667 0.0235294117647059
HP HP:0001697 Abnormal pericardium morphology 0.00250434979296275 68 5 3 0.6 0.0441176470588235
HP HP:0000763 Sensory neuropathy 0.00250434979296275 182 6 4 0.666666666666667 0.021978021978022
HP HP:0002206 Pulmonary fibrosis 0.00250434979296275 69 5 3 0.6 0.0434782608695652
HP HP:0031983 Abnormal pulmonary thoracic imaging finding 0.00250434979296275 71 5 3 0.6 0.0422535211267606
HP HP:0001287 Meningitis 0.00250434979296275 72 5 3 0.6 0.0416666666666667
HP HP:0002091 Restrictive ventilatory defect 0.0031759998019941 80 5 3 0.6 0.0375
HP HP:0002103 Abnormal pleura morphology 0.00354210506348175 84 5 3 0.6 0.0357142857142857
HP HP:0011123 Inflammatory abnormality of the skin 0.00361197543660278 367 7 5 0.714285714285714 0.0136239782016349
HP HP:0011450 Unusual CNS infection 0.0036648081037568 87 5 3 0.6 0.0344827586206897
HP HP:0032158 Unusual infection by anatomical site 0.00405486546763435 91 5 3 0.6 0.032967032967033
HP HP:0005356 Decreased serum complement factor I 0.0043030047515076 7 63 3 0.0476190476190476 0.428571428571429
HP HP:0000793 Membranoproliferative glomerulonephritis 0.0043030047515076 7 63 3 0.0476190476190476 0.428571428571429
HP HP:0032016 Abnormal sputum 0.00565277922992065 106 5 3 0.6 0.0283018867924528
HP HP:0200042 Skin ulcer 0.00700642042373791 115 5 3 0.6 0.0260869565217391
HP HP:0001824 Weight loss 0.00786355095605311 273 6 4 0.666666666666667 0.0146520146520147
HP HP:0000421 Epistaxis 0.00895871654863632 86 7 3 0.428571428571429 0.0348837209302326
HP HP:0030878 Abnormality on pulmonary function testing 0.00895871654863632 128 5 3 0.6 0.0234375
HP HP:0010876 Abnormal circulating protein concentration 0.00930667322226539 480 7 5 0.714285714285714 0.0104166666666667
HP HP:0011276 Vascular skin abnormality 0.0102502394382546 493 7 5 0.714285714285714 0.0101419878296146
HP HP:0006530 Abnormal pulmonary Interstitial morphology 0.0102502394382546 140 5 3 0.6 0.0214285714285714
HP HP:0031263 Abnormal renal corpuscle morphology 0.0103306071262145 158 63 9 0.142857142857143 0.0569620253164557
HP HP:0000095 Abnormal renal glomerulus morphology 0.0103306071262145 158 63 9 0.142857142857143 0.0569620253164557
HP HP:0000979 Purpura 0.0125341364178285 104 7 3 0.428571428571429 0.0288461538461538
HP HP:0012733 Macule 0.0125883472731356 106 7 3 0.428571428571429 0.0283018867924528
HP HP:0002829 Arthralgia 0.0125883472731356 161 5 3 0.6 0.0186335403726708
HP HP:0012575 Abnormal nephron morphology 0.0137607817939768 208 63 10 0.158730158730159 0.0480769230769231
HP HP:0001945 Fever 0.0137607817939768 294 7 4 0.571428571428571 0.0136054421768707
HP HP:0001426 Multifactorial inheritance 0.0162459051275938 84 10 3 0.3 0.0357142857142857
HP HP:0010974 Abnormal myeloid leukocyte morphology 0.0162459051275938 312 7 4 0.571428571428571 0.0128205128205128
HP HP:0100533 Inflammatory abnormality of the eye 0.017025479629582 193 5 3 0.6 0.0155440414507772
HP HP:0002725 Systemic lupus erythematosus 0.0206550726288706 32 63 4 0.0634920634920635 0.125
HP HP:0000099 Glomerulonephritis 0.0226213857536274 33 63 4 0.0634920634920635 0.121212121212121
HP HP:0011035 Abnormal renal cortex morphology 0.0226213857536274 187 63 9 0.142857142857143 0.0481283422459893
HP HP:0004374 Hemiplegia/hemiparesis 0.0270589607834553 199 6 3 0.5 0.0150753768844221
HP HP:0011675 Arrhythmia 0.0270589607834553 381 7 4 0.571428571428571 0.010498687664042
HP HP:0030163 Abnormal vascular physiology 0.0270589607834553 248 5 3 0.6 0.0120967741935484
HP HP:0002027 Abdominal pain 0.0271227309712497 251 5 3 0.6 0.0119521912350598
HP HP:0002633 Vasculitis 0.0272014407360488 65 60 5 0.0833333333333333 0.0769230769230769
HP HP:0004370 Abnormality of temperature regulation 0.0280605231324145 398 7 4 0.571428571428571 0.0100502512562814
HP HP:0002719 Recurrent infections 0.0305452544127471 745 7 5 0.714285714285714 0.00671140939597315
HP HP:0011799 Abnormality of facial soft tissue 0.0305452544127471 413 7 4 0.571428571428571 0.00968523002421308
HP HP:0030956 Abnormality of cardiovascular system electrophysiology 0.032873551717188 424 7 4 0.571428571428571 0.00943396226415094
HP HP:0006824 Cranial nerve paralysis 0.0341049086460497 287 5 3 0.6 0.0104529616724739
HP HP:0031910 Abnormal cranial nerve physiology 0.0341328530386901 288 5 3 0.6 0.0104166666666667
HP HP:0032101 Unusual infection 0.036282720196746 792 7 5 0.714285714285714 0.00631313131313131
HP HP:0011355 Localized skin lesion 0.0377850373334595 805 7 5 0.714285714285714 0.0062111801242236
HP HP:0000822 Hypertension 0.03781793403483 306 5 3 0.6 0.00980392156862745
HP HP:0001933 Subcutaneous hemorrhage 0.039698967639022 211 7 3 0.428571428571429 0.014218009478673
HP HP:0009830 Peripheral neuropathy 0.0422814717570915 588 6 4 0.666666666666667 0.00680272108843537
HP HP:0012378 Fatigue 0.0432960201748155 335 5 3 0.6 0.00895522388059702
HP HP:0000083 Renal insufficiency 0.0437162037583336 337 5 3 0.6 0.00890207715133531
HP HP:0032263 Increased blood pressure 0.0459981416528826 350 5 3 0.6 0.00857142857142857
HP HP:0011354 Generalized abnormality of skin 0.0459981416528826 876 7 5 0.714285714285714 0.00570776255707763
HP HP:0001881 Abnormal leukocyte morphology 0.0460112060141409 510 7 4 0.571428571428571 0.00784313725490196
HP HP:0010987 Abnormal cellular immune system morphology 0.0460112060141409 510 7 4 0.571428571428571 0.00784313725490196
HP HP:0012531 Pain 0.0461576356961696 636 6 4 0.666666666666667 0.00628930817610063
HP HP:0012647 Abnormal inflammatory response 0.0485495710381476 914 7 5 0.714285714285714 0.00547045951859956
HP HP:0012649 Increased inflammatory response 0.0485495710381476 914 7 5 0.714285714285714 0.00547045951859956
HP HP:0032251 Abnormal immune system morphology 0.0485495710381476 532 7 4 0.571428571428571 0.0075187969924812
HPA HPA:0310443 lymph node; non-germinal center cells[High] 0.0342950703399682 1169 10 6 0.6 0.00513259195893926
HPA HPA:0310433 lymph node; germinal center cells[High] 0.0342950703399682 908 8 5 0.625 0.00550660792951542
HPA HPA:0090973 cerebellum; granular cells - cytoplasm/membrane[High] 0.0342950703399682 132 10 3 0.3 0.0227272727272727
HPA HPA:0600443 tonsil; non-germinal center cells[High] 0.0410392917431426 1271 10 6 0.6 0.004720692368214
HPA HPA:0090972 cerebellum; granular cells - cytoplasm/membrane[≥Medium] 0.0424728399422818 231 115 9 0.0782608695652174 0.038961038961039
HPA HPA:0091003 cerebellum; molecular layer cells - cytoplasm/membrane[High] 0.0424728399422818 182 10 3 0.3 0.0164835164835165
HPA HPA:0300413 lung; macrophages[High] 0.0424728399422818 1224 8 5 0.625 0.00408496732026144
HPA HPA:0530722 spleen; cells in white pulp[≥Medium] 0.0424728399422818 2645 13 9 0.692307692307692 0.00340264650283554
HPA HPA:0600433 tonsil; germinal center cells[High] 0.0424728399422818 1179 8 5 0.625 0.00424088210347752
KEGG KEGG:05330 Allograft rejection 6.54835081678895e-16 34 11 8 0.727272727272727 0.235294117647059
KEGG KEGG:04612 Antigen processing and presentation 6.54835081678895e-16 69 11 9 0.818181818181818 0.130434782608696
KEGG KEGG:05332 Graft-versus-host disease 7.95458627646843e-16 37 11 8 0.727272727272727 0.216216216216216
KEGG KEGG:04940 Type I diabetes mellitus 1.18718380056483e-15 40 11 8 0.727272727272727 0.2
KEGG KEGG:05310 Asthma 2.06263537023353e-14 27 20 8 0.4 0.296296296296296
KEGG KEGG:05321 Inflammatory bowel disease 3.45405163590927e-14 62 11 8 0.727272727272727 0.129032258064516
KEGG KEGG:04672 Intestinal immune network for IgA production 5.80375150791158e-14 45 24 9 0.375 0.2
KEGG KEGG:04658 Th1 and Th2 cell differentiation 5.80375150791158e-14 89 20 10 0.5 0.112359550561798
KEGG KEGG:05140 Leishmaniasis 8.12418472381186e-14 72 11 8 0.727272727272727 0.111111111111111
KEGG KEGG:04659 Th17 cell differentiation 2.22003701868227e-13 104 14 9 0.642857142857143 0.0865384615384615
KEGG KEGG:05323 Rheumatoid arthritis 3.55049916095848e-13 88 11 8 0.727272727272727 0.0909090909090909
KEGG KEGG:05152 Tuberculosis 5.84638516975229e-13 175 8 8 1 0.0457142857142857
KEGG KEGG:05320 Autoimmune thyroid disease 8.09137204276784e-13 49 11 7 0.636363636363636 0.142857142857143
KEGG KEGG:05145 Toxoplasmosis 1.63721315416027e-12 109 11 8 0.727272727272727 0.073394495412844
KEGG KEGG:05416 Viral myocarditis 1.88744319803969e-12 56 11 7 0.636363636363636 0.125
KEGG KEGG:04640 Hematopoietic cell lineage 4.72003315189099e-12 95 20 9 0.45 0.0947368421052632
KEGG KEGG:05322 Systemic lupus erythematosus 6.48459589358598e-12 132 11 8 0.727272727272727 0.0606060606060606
KEGG KEGG:05150 Staphylococcus aureus infection 1.85722267203843e-11 87 63 12 0.19047619047619 0.137931034482759
KEGG KEGG:04514 Cell adhesion molecules 3.91340588865451e-11 146 24 10 0.416666666666667 0.0684931506849315
KEGG KEGG:05164 Influenza A 4.123201416243e-11 169 11 8 0.727272727272727 0.0473372781065089
KEGG KEGG:04145 Phagosome 1.42150285275837e-09 147 11 7 0.636363636363636 0.0476190476190476
KEGG KEGG:05168 Herpes simplex virus 1 infection 1.42862192056543e-09 494 8 8 1 0.0161943319838057
KEGG KEGG:05169 Epstein-Barr virus infection 2.20588345121767e-09 198 14 8 0.571428571428571 0.0404040404040404
KEGG KEGG:05166 Human T-cell leukemia virus 1 infection 4.23960124887129e-09 216 14 8 0.571428571428571 0.037037037037037
KEGG KEGG:05142 Chagas disease 8.96810396252497e-05 101 64 7 0.109375 0.0693069306930693
KEGG KEGG:05143 African trypanosomiasis 0.00445203461757387 36 40 3 0.075 0.0833333333333333
KEGG KEGG:05133 Pertussis 0.0184180462049249 76 65 4 0.0615384615384615 0.0526315789473684
REAC REAC:R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 2.02251148413235e-11 20 14 6 0.428571428571429 0.3
REAC REAC:R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 2.33499545630777e-11 23 14 6 0.428571428571429 0.260869565217391
REAC REAC:R-HSA-389948 PD-1 signaling 2.33499545630777e-11 24 14 6 0.428571428571429 0.25
REAC REAC:R-HSA-2132295 MHC class II antigen presentation 3.74925849093427e-11 123 20 9 0.45 0.0731707317073171
REAC REAC:R-HSA-202433 Generation of second messenger molecules 1.67745780932241e-10 35 14 6 0.428571428571429 0.171428571428571
REAC REAC:R-HSA-877300 Interferon gamma signaling 1.87047509679107e-10 87 13 7 0.538461538461538 0.0804597701149425
REAC REAC:R-HSA-388841 Costimulation by the CD28 family 7.21438093673052e-09 67 14 6 0.428571428571429 0.0895522388059701
REAC REAC:R-HSA-913531 Interferon Signaling 3.75070575534171e-08 191 13 7 0.538461538461538 0.0366492146596859
REAC REAC:R-HSA-202424 Downstream TCR signaling 5.79966711283103e-08 98 14 6 0.428571428571429 0.0612244897959184
REAC REAC:R-HSA-202403 TCR signaling 1.78537622424739e-07 120 14 6 0.428571428571429 0.05
REAC REAC:R-HSA-1280218 Adaptive Immune System 3.84869985861711e-07 800 15 10 0.666666666666667 0.0125
REAC REAC:R-HSA-168256 Immune System 0.000394072282158719 2139 15 11 0.733333333333333 0.00514258999532492
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 0.000580811950897556 842 13 7 0.538461538461538 0.00831353919239905
REAC REAC:R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 0.0258311618264571 181 27 4 0.148148148148148 0.0220994475138122
REAC REAC:R-HSA-216083 Integrin cell surface interactions 0.0498845718366493 84 33 3 0.0909090909090909 0.0357142857142857
TF TF:M02162_1 Factor: HNF1A; motif: GGTTAATNATTAMC; match class: 1 0.0437393008790747 70 11 3 0.272727272727273 0.0428571428571429
TF TF:M03810 Factor: RXR:PXR; motif: NNNTGAMCTYNNNTGAMCYN 0.0467906206217402 1360 24 8 0.333333333333333 0.00588235294117647
TF TF:M02078 Factor: SPI1; motif: NGRGGAAGTN 0.0467906206217402 3506 96 33 0.34375 0.0094124358243012
TF TF:M03881 Factor: NFAT5; motif: ANTGGAAARTYMCN 0.0467906206217402 38 104 4 0.0384615384615385 0.105263157894737
TF TF:M11208 Factor: AP-4; motif: AWCAGCTGWT 0.0467906206217402 4183 32 17 0.53125 0.00406406885010758
TF TF:M11268 Factor: JunD; motif: NATGASTCATS 0.0467906206217402 2941 22 11 0.5 0.00374022441346481
TF TF:M11210_1 Factor: AP-4; motif: AWCAGCTGWT; match class: 1 0.0467906206217402 4621 53 25 0.471698113207547 0.0054100843973166
TF TF:M04498_1 Factor: VDR; motif: GRGTTCATYGRGTTCA; match class: 1 0.0467906206217402 876 19 6 0.315789473684211 0.00684931506849315
TF TF:M10161_1 Factor: ZNF667; motif: GNGSCYTNMARAGCTCMNC; match class: 1 0.0467906206217402 394 95 9 0.0947368421052632 0.0228426395939086
TF TF:M00790_1 Factor: HNF-1; motif: WRGTTAATNATTAACNNN; match class: 1 0.0467906206217402 372 11 4 0.363636363636364 0.010752688172043
TF TF:M07044_1 Factor: HNF-1alpha; motif: NGNNAAWNATTAACNN; match class: 1 0.0467906206217402 147 11 3 0.272727272727273 0.0204081632653061
TF TF:M12212 Factor: gli3; motif: RGACCACCCACRNWG 0.0467906206217402 647 103 12 0.116504854368932 0.0185471406491499
TF TF:M07222 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR 0.0467906206217402 714 11 5 0.454545454545455 0.00700280112044818
TF TF:M01968 Factor: FOXO1; motif: TGTTKAC 0.0467906206217402 2612 68 21 0.308823529411765 0.00803981623277182
TF TF:M09839 Factor: ATF4; motif: ATTGCATCAT 0.0467906206217402 2145 4 4 1 0.00186480186480186
TF TF:M11210 Factor: AP-4; motif: AWCAGCTGWT 0.0467906206217402 4621 53 25 0.471698113207547 0.0054100843973166
TF TF:M00185 Factor: NF-Y; motif: TRRCCAATSRN 0.0467906206217402 870 11 5 0.454545454545455 0.00574712643678161
TF TF:M04192_1 Factor: TFAP4; motif: AWCAGCTGWT; match class: 1 0.0473190657997382 4111 53 23 0.433962264150943 0.00559474580394065
TF TF:M04192 Factor: TFAP4; motif: AWCAGCTGWT 0.0473190657997382 5299 53 27 0.509433962264151 0.00509530100018871
TF TF:M00172 Factor: AP-1; motif: RSTGACTNMNW 0.0473190657997382 2280 52 16 0.307692307692308 0.00701754385964912
TF TF:M11208_1 Factor: AP-4; motif: AWCAGCTGWT; match class: 1 0.0473190657997382 3864 27 14 0.518518518518518 0.0036231884057971
TF TF:M07292 Factor: GLI; motif: NTGGGTGGTN 0.0473190657997382 5763 98 46 0.469387755102041 0.0079819538434843
TF TF:M01202 Factor: VDR:RXR; motif: GGGTCAWNGRGTTCA 0.0485749783157134 3938 124 42 0.338709677419355 0.01066531234129
WP WP:WP2328 Allograft Rejection 6.37970538811511e-14 88 65 15 0.230769230769231 0.170454545454545
WP WP:WP4217 Ebola Virus Pathway on Host 1.04633708434689e-08 130 11 7 0.636363636363636 0.0538461538461538
WP WP:WP4884 Pathogenesis of SARS-CoV-2 Mediated by nsp9-nsp10 Complex 2.5816726685614e-06 21 14 4 0.285714285714286 0.19047619047619
WP WP:WP530 Cytokines and Inflammatory Response 5.62140665210504e-05 26 7 3 0.428571428571429 0.115384615384615
WP WP:WP4146 Macrophage markers 0.000256197845436491 9 120 4 0.0333333333333333 0.444444444444444
WP WP:WP4585 Cancer immunotherapy by PD-1 blockade 0.000262136009994023 23 14 3 0.214285714285714 0.130434782608696
WP WP:WP3941 Oxidative Damage 0.0101580234180419 41 65 4 0.0615384615384615 0.0975609756097561
WP WP:WP545 Complement Activation 0.0170274442520191 22 63 3 0.0476190476190476 0.136363636363636

pTNI06 transcription factor target enrichment of top program genes

TF enrichment of pTNI06
TFs corrosponding to activation of pTNI06. (Left) pearson correlation of TF expression and gene expression program activatity in T/NK/ILC cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.