pMA02 program activity among Mast cells

Activation of pMA02
pMA02 gene program activation in Mast cells.
Gene program activation of pMA02 by different cell subtypes
pMA02 gene program activation among cells of different subtypes (Mast cells).

pMA02 top program genes

Top genes of pMA02 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pMA02 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pMA02
pMA02 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0002376 immune system process 3.1907033302534e-20 3278 128 74 0.578125 0.0225747406955461
GO:BP GO:0001775 cell activation 1.8935322324004e-19 1495 76 39 0.513157894736842 0.0260869565217391
GO:BP GO:0002252 immune effector process 1.8935322324004e-19 1309 76 37 0.486842105263158 0.0282658517952636
GO:BP GO:0006955 immune response 1.99815286864672e-19 2311 86 49 0.569767441860465 0.0212029424491562
GO:BP GO:0019221 cytokine-mediated signaling pathway 3.41503875636819e-19 810 51 26 0.509803921568627 0.0320987654320988
GO:BP GO:0071345 cellular response to cytokine stimulus 7.46257394147191e-19 1132 70 33 0.471428571428571 0.0291519434628975
GO:BP GO:0045321 leukocyte activation 9.41770141321585e-19 1332 128 47 0.3671875 0.0352852852852853
GO:BP GO:0034097 response to cytokine 6.61845695885787e-18 1226 70 33 0.471428571428571 0.0269168026101142
GO:BP GO:0034341 response to interferon-gamma 3.00822740558587e-17 196 32 14 0.4375 0.0714285714285714
GO:BP GO:0001817 regulation of cytokine production 5.91815541856933e-17 806 73 28 0.383561643835616 0.0347394540942928
GO:BP GO:0002443 leukocyte mediated immunity 6.10328287764995e-17 877 86 31 0.36046511627907 0.0353477765108324
GO:BP GO:0001816 cytokine production 1.66436297164198e-16 844 73 28 0.383561643835616 0.033175355450237
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.79350427646764e-16 174 63 16 0.253968253968254 0.0919540229885057
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 3.46174114688087e-16 182 63 16 0.253968253968254 0.0879120879120879
GO:BP GO:0019882 antigen processing and presentation 3.74802539760088e-16 234 131 22 0.16793893129771 0.094017094017094
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 7.21220491660876e-16 192 63 16 0.253968253968254 0.0833333333333333
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 1.23074847804822e-15 2255 87 44 0.505747126436782 0.0195121951219512
GO:BP GO:0060337 type I interferon signaling pathway 1.73836592546079e-15 95 83 14 0.168674698795181 0.147368421052632
GO:BP GO:0002366 leukocyte activation involved in immune response 1.91453613958283e-15 717 100 29 0.29 0.0404463040446304
GO:BP GO:0071357 cellular response to type I interferon 1.91453613958283e-15 96 83 14 0.168674698795181 0.145833333333333
GO:BP GO:0002263 cell activation involved in immune response 2.11596677399249e-15 721 100 29 0.29 0.0402219140083218
GO:BP GO:0034340 response to type I interferon 3.49377377661942e-15 101 83 14 0.168674698795181 0.138613861386139
GO:BP GO:0070887 cellular response to chemical stimulus 3.66856444176004e-15 3393 79 49 0.620253164556962 0.0144414972001179
GO:BP GO:0045087 innate immune response 1.32019799166295e-14 998 69 27 0.391304347826087 0.0270541082164329
GO:BP GO:0043299 leukocyte degranulation 1.46785596941229e-14 535 100 25 0.25 0.0467289719626168
GO:BP GO:0098542 defense response to other organism 1.74614034580198e-14 1218 69 29 0.420289855072464 0.0238095238095238
GO:BP GO:0002444 myeloid leukocyte mediated immunity 2.70430634446962e-14 551 100 25 0.25 0.0453720508166969
GO:BP GO:0016032 viral process 2.76377277543744e-14 942 87 29 0.333333333333333 0.0307855626326964
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 3.1299827064934e-14 88 32 10 0.3125 0.113636363636364
GO:BP GO:0006952 defense response 3.1299827064934e-14 1818 74 35 0.472972972972973 0.0192519251925193
GO:BP GO:0009607 response to biotic stimulus 4.81703374379521e-14 1626 69 32 0.463768115942029 0.019680196801968
GO:BP GO:0002682 regulation of immune system process 7.65147051544076e-14 1617 58 29 0.5 0.0179344465058751
GO:BP GO:0044403 biological process involved in symbiotic interaction 1.1562942503756e-13 1001 87 29 0.333333333333333 0.028971028971029
GO:BP GO:0045055 regulated exocytosis 1.15828561302913e-13 785 100 28 0.28 0.0356687898089172
GO:BP GO:0071310 cellular response to organic substance 1.63789811141802e-13 2776 27 23 0.851851851851852 0.00828530259365994
GO:BP GO:0002274 myeloid leukocyte activation 1.74566789573808e-13 667 100 26 0.26 0.0389805097451274
GO:BP GO:0002275 myeloid cell activation involved in immune response 1.84180656392913e-13 547 100 24 0.24 0.0438756855575868
GO:BP GO:0051707 response to other organism 1.9138496012317e-13 1592 69 31 0.449275362318841 0.0194723618090452
GO:BP GO:0043207 response to external biotic stimulus 1.93093268370771e-13 1594 69 31 0.449275362318841 0.0194479297365119
GO:BP GO:0019883 antigen processing and presentation of endogenous antigen 2.1394963583741e-13 26 49 8 0.163265306122449 0.307692307692308
GO:BP GO:0006950 response to stress 3.23426675131178e-13 4170 79 51 0.645569620253165 0.0122302158273381
GO:BP GO:0043312 neutrophil degranulation 1.28846460558127e-12 482 100 22 0.22 0.045643153526971
GO:BP GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent 1.3132520837144e-12 8 4 4 1 0.5
GO:BP GO:0002283 neutrophil activation involved in immune response 1.39631677515713e-12 485 100 22 0.22 0.045360824742268
GO:BP GO:0002446 neutrophil mediated immunity 2.24854863521589e-12 497 100 22 0.22 0.0442655935613682
GO:BP GO:0042119 neutrophil activation 2.29163998262185e-12 498 100 22 0.22 0.0441767068273092
GO:BP GO:0002483 antigen processing and presentation of endogenous peptide antigen 2.5625754060248e-12 19 49 7 0.142857142857143 0.368421052631579
GO:BP GO:0010033 response to organic substance 2.59520285518743e-12 3412 28 24 0.857142857142857 0.00703399765533412
GO:BP GO:0006887 exocytosis 2.7145217283346e-12 904 100 28 0.28 0.0309734513274336
GO:BP GO:0036230 granulocyte activation 2.7145217283346e-12 504 100 22 0.22 0.0436507936507936
GO:BP GO:0019058 viral life cycle 4.28357799082428e-12 353 87 18 0.206896551724138 0.0509915014164306
GO:BP GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 1.5116850655679e-11 75 131 12 0.0916030534351145 0.16
GO:BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.97177623760698e-11 99 131 13 0.099236641221374 0.131313131313131
GO:BP GO:0071346 cellular response to interferon-gamma 1.97177623760698e-11 175 32 10 0.3125 0.0571428571428571
GO:BP GO:0001819 positive regulation of cytokine production 2.33129573235006e-11 452 26 12 0.461538461538462 0.0265486725663717
GO:BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 3.14011014299439e-11 80 131 12 0.0916030534351145 0.15
GO:BP GO:0050776 regulation of immune response 3.86308598306504e-11 996 56 21 0.375 0.0210843373493976
GO:BP GO:0007166 cell surface receptor signaling pathway 5.40847821365093e-11 3210 70 39 0.557142857142857 0.0121495327102804
GO:BP GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent 6.08865877684114e-11 3 3 3 1 1
GO:BP GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway 6.08865877684114e-11 3 3 3 1 1
GO:BP GO:0042221 response to chemical 7.14474287348163e-11 4781 79 51 0.645569620253165 0.0106672244300356
GO:BP GO:0048584 positive regulation of response to stimulus 8.008932209358e-11 2344 58 30 0.517241379310345 0.0127986348122867
GO:BP GO:0032940 secretion by cell 8.008932209358e-11 1364 102 32 0.313725490196078 0.0234604105571848
GO:BP GO:0046903 secretion 1.85908483277414e-10 1501 102 33 0.323529411764706 0.0219853431045969
GO:BP GO:0046649 lymphocyte activation 2.14825805011248e-10 771 128 27 0.2109375 0.0350194552529183
GO:BP GO:0140352 export from cell 2.14825805011248e-10 1418 102 32 0.313725490196078 0.0225669957686883
GO:BP GO:0042110 T cell activation 2.19875324356449e-10 489 128 22 0.171875 0.0449897750511247
GO:BP GO:0051649 establishment of localization in cell 3.01505188796494e-10 2813 102 45 0.441176470588235 0.0159971560611447
GO:BP GO:0002684 positive regulation of immune system process 5.17409063658235e-10 1065 144 33 0.229166666666667 0.0309859154929577
GO:BP GO:0051249 regulation of lymphocyte activation 6.50505528138528e-10 518 128 22 0.171875 0.0424710424710425
GO:BP GO:0002520 immune system development 6.71553252515094e-10 1020 127 30 0.236220472440945 0.0294117647058824
GO:BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 7.30292076112759e-10 241 128 16 0.125 0.0663900414937759
GO:BP GO:0048583 regulation of response to stimulus 7.70858550371915e-10 4278 70 43 0.614285714285714 0.0100514258999532
GO:BP GO:0007159 leukocyte cell-cell adhesion 8.78288773300306e-10 375 128 19 0.1484375 0.0506666666666667
GO:BP GO:0009605 response to external stimulus 1.0152441162475e-09 2944 91 42 0.461538461538462 0.0142663043478261
GO:BP GO:0007165 signal transduction 1.0152441162475e-09 6309 27 26 0.962962962962963 0.00412109684577588
GO:BP GO:1903037 regulation of leukocyte cell-cell adhesion 1.32620496542883e-09 338 128 18 0.140625 0.0532544378698225
GO:BP GO:0050778 positive regulation of immune response 1.37986764175411e-09 753 69 19 0.27536231884058 0.0252324037184595
GO:BP GO:0030097 hemopoiesis 1.84513773102859e-09 928 127 28 0.220472440944882 0.0301724137931034
GO:BP GO:0002694 regulation of leukocyte activation 2.0229047793354e-09 610 128 23 0.1796875 0.0377049180327869
GO:BP GO:0002711 positive regulation of T cell mediated immunity 2.74987192185951e-09 48 51 7 0.137254901960784 0.145833333333333
GO:BP GO:0001916 positive regulation of T cell mediated cytotoxicity 2.78074636816996e-09 26 49 6 0.122448979591837 0.230769230769231
GO:BP GO:0042270 protection from natural killer cell mediated cytotoxicity 3.52071468974256e-09 6 4 3 0.75 0.5
GO:BP GO:0002697 regulation of immune effector process 3.6952543924145e-09 461 56 14 0.25 0.0303687635574837
GO:BP GO:0051251 positive regulation of lymphocyte activation 4.23641115596514e-09 365 128 18 0.140625 0.0493150684931507
GO:BP GO:0048534 hematopoietic or lymphoid organ development 4.2954228747408e-09 966 127 28 0.220472440944882 0.0289855072463768
GO:BP GO:0051240 positive regulation of multicellular organismal process 4.73345640656975e-09 1455 26 15 0.576923076923077 0.0103092783505155
GO:BP GO:0051716 cellular response to stimulus 4.73345640656975e-09 7781 79 62 0.784810126582278 0.00796812749003984
GO:BP GO:0051239 regulation of multicellular organismal process 4.77880520237425e-09 2861 127 50 0.393700787401575 0.0174764068507515
GO:BP GO:1903706 regulation of hemopoiesis 5.14427366345104e-09 424 127 19 0.149606299212598 0.044811320754717
GO:BP GO:0023052 signaling 5.95778193755587e-09 6810 27 26 0.962962962962963 0.00381791483113069
GO:BP GO:0007154 cell communication 6.3265651161007e-09 6829 27 26 0.962962962962963 0.00380729242934544
GO:BP GO:0022409 positive regulation of cell-cell adhesion 6.56728256560399e-09 284 128 16 0.125 0.0563380281690141
GO:BP GO:0050865 regulation of cell activation 7.04298329552825e-09 655 128 23 0.1796875 0.0351145038167939
GO:BP GO:0030155 regulation of cell adhesion 7.41025292641873e-09 748 144 26 0.180555555555556 0.0347593582887701
GO:BP GO:0050863 regulation of T cell activation 9.14221914155202e-09 337 128 17 0.1328125 0.0504451038575668
GO:BP GO:0070661 leukocyte proliferation 1.02046553947497e-08 325 25 9 0.36 0.0276923076923077
GO:BP GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 1.06613657765913e-08 13 3 3 1 0.230769230769231
GO:BP GO:0022407 regulation of cell-cell adhesion 1.21522801909712e-08 445 128 19 0.1484375 0.0426966292134831
GO:BP GO:0080134 regulation of response to stress 1.2439154978654e-08 1443 70 24 0.342857142857143 0.0166320166320166
GO:BP GO:0002699 positive regulation of immune effector process 1.30987721316482e-08 215 67 11 0.164179104477612 0.0511627906976744
GO:BP GO:0061077 chaperone-mediated protein folding 1.42861422816127e-08 61 28 6 0.214285714285714 0.0983606557377049
GO:BP GO:0001914 regulation of T cell mediated cytotoxicity 1.53240613539194e-08 35 49 6 0.122448979591837 0.171428571428571
GO:BP GO:0050852 T cell receptor signaling pathway 1.64055393472115e-08 203 55 10 0.181818181818182 0.0492610837438424
GO:BP GO:0050870 positive regulation of T cell activation 1.66966311765664e-08 219 128 14 0.109375 0.0639269406392694
GO:BP GO:0050896 response to stimulus 1.74878319387737e-08 9407 102 83 0.813725490196078 0.00882321675348145
GO:BP GO:0002456 T cell mediated immunity 1.83177335162536e-08 98 55 8 0.145454545454545 0.0816326530612245
GO:BP GO:0048525 negative regulation of viral process 1.83987767910343e-08 94 85 9 0.105882352941176 0.0957446808510638
GO:BP GO:0002696 positive regulation of leukocyte activation 2.3329223602214e-08 412 128 18 0.140625 0.0436893203883495
GO:BP GO:0002718 regulation of cytokine production involved in immune response 2.87445257191104e-08 85 67 8 0.119402985074627 0.0941176470588235
GO:BP GO:0016192 vesicle-mediated transport 2.91978317097149e-08 2180 102 36 0.352941176470588 0.0165137614678899
GO:BP GO:0070663 regulation of leukocyte proliferation 3.46307663333502e-08 251 25 8 0.32 0.0318725099601594
GO:BP GO:0050867 positive regulation of cell activation 3.55524858250398e-08 424 128 18 0.140625 0.0424528301886792
GO:BP GO:0070665 positive regulation of leukocyte proliferation 3.92781073933059e-08 155 25 7 0.28 0.0451612903225806
GO:BP GO:0001913 T cell mediated cytotoxicity 4.37288826168812e-08 42 49 6 0.122448979591837 0.142857142857143
GO:BP GO:0002709 regulation of T cell mediated immunity 4.40234137923466e-08 74 51 7 0.137254901960784 0.0945945945945946
GO:BP GO:0046718 viral entry into host cell 4.40234137923466e-08 141 87 10 0.114942528735632 0.0709219858156028
GO:BP GO:0050792 regulation of viral process 4.66143121192553e-08 192 85 11 0.129411764705882 0.0572916666666667
GO:BP GO:0002367 cytokine production involved in immune response 4.66143121192553e-08 94 11 5 0.454545454545455 0.0531914893617021
GO:BP GO:0032101 regulation of response to external stimulus 4.74210584239185e-08 1051 70 20 0.285714285714286 0.0190294957183635
GO:BP GO:0002440 production of molecular mediator of immune response 5.32982095527299e-08 189 67 10 0.149253731343284 0.0529100529100529
GO:BP GO:0002704 negative regulation of leukocyte mediated immunity 5.7475887137192e-08 51 7 4 0.571428571428571 0.0784313725490196
GO:BP GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 6.64939247852497e-08 16 4 3 0.75 0.1875
GO:BP GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.80514377567258e-08 96 67 8 0.119402985074627 0.0833333333333333
GO:BP GO:1903900 regulation of viral life cycle 7.23266618017372e-08 153 85 10 0.117647058823529 0.065359477124183
GO:BP GO:0048585 negative regulation of response to stimulus 7.83049008133117e-08 1733 27 15 0.555555555555556 0.00865551067512983
GO:BP GO:0002716 negative regulation of natural killer cell mediated immunity 7.83049008133117e-08 17 4 3 0.75 0.176470588235294
GO:BP GO:0043903 regulation of biological process involved in symbiotic interaction 7.83049008133117e-08 203 85 11 0.129411764705882 0.0541871921182266
GO:BP GO:0002250 adaptive immune response 8.3232870097799e-08 689 67 16 0.238805970149254 0.02322206095791
GO:BP GO:0002683 negative regulation of immune system process 9.00842582055262e-08 420 122 17 0.139344262295082 0.0404761904761905
GO:BP GO:0044409 entry into host 9.26552173011299e-08 154 87 10 0.114942528735632 0.0649350649350649
GO:BP GO:0002821 positive regulation of adaptive immune response 9.60262389179519e-08 101 67 8 0.119402985074627 0.0792079207920792
GO:BP GO:0051641 cellular localization 1.04369744271384e-07 3541 102 46 0.450980392156863 0.0129906805987009
GO:BP GO:0002703 regulation of leukocyte mediated immunity 1.05595283931459e-07 205 67 10 0.149253731343284 0.0487804878048781
GO:BP GO:0002708 positive regulation of lymphocyte mediated immunity 1.18630142969722e-07 104 67 8 0.119402985074627 0.0769230769230769
GO:BP GO:0010941 regulation of cell death 1.20516266035376e-07 1720 127 35 0.275590551181102 0.0203488372093023
GO:BP GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1.21509816456937e-07 20 4 3 0.75 0.15
GO:BP GO:0001912 positive regulation of leukocyte mediated cytotoxicity 1.22832435116815e-07 51 49 6 0.122448979591837 0.117647058823529
GO:BP GO:0050670 regulation of lymphocyte proliferation 1.33675238900548e-07 230 122 13 0.10655737704918 0.0565217391304348
GO:BP GO:0032944 regulation of mononuclear cell proliferation 1.47314691138927e-07 232 122 13 0.10655737704918 0.0560344827586207
GO:BP GO:0045639 positive regulation of myeloid cell differentiation 1.57096059134766e-07 103 26 6 0.230769230769231 0.058252427184466
GO:BP GO:0050790 regulation of catalytic activity 1.76659072157694e-07 2545 138 46 0.333333333333333 0.0180746561886051
GO:BP GO:0032649 regulation of interferon-gamma production 1.78180582823622e-07 110 25 6 0.24 0.0545454545454545
GO:BP GO:0031342 negative regulation of cell killing 2.05212170204374e-07 24 4 3 0.75 0.125
GO:BP GO:0002831 regulation of response to biotic stimulus 2.09051420361657e-07 415 100 15 0.15 0.036144578313253
GO:BP GO:0002720 positive regulation of cytokine production involved in immune response 2.11093814710442e-07 54 51 6 0.117647058823529 0.111111111111111
GO:BP GO:1903131 mononuclear cell differentiation 2.11093814710442e-07 430 127 17 0.133858267716535 0.0395348837209302
GO:BP GO:1902105 regulation of leukocyte differentiation 2.16175163945194e-07 288 122 14 0.114754098360656 0.0486111111111111
GO:BP GO:0032609 interferon-gamma production 2.23636916299419e-07 115 25 6 0.24 0.0521739130434783
GO:BP GO:0090083 regulation of inclusion body assembly 2.56776072386912e-07 17 28 4 0.142857142857143 0.235294117647059
GO:BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.56776072386912e-07 103 108 9 0.0833333333333333 0.087378640776699
GO:BP GO:0065009 regulation of molecular function 2.67245357082734e-07 3221 143 54 0.377622377622378 0.0167649798199317
GO:BP GO:0031343 positive regulation of cell killing 2.72701353123647e-07 59 49 6 0.122448979591837 0.101694915254237
GO:BP GO:0045785 positive regulation of cell adhesion 2.8471778421227e-07 437 144 18 0.125 0.0411899313501144
GO:BP GO:0031347 regulation of defense response 2.85046702531187e-07 704 124 21 0.169354838709677 0.0298295454545455
GO:BP GO:0009615 response to virus 2.85046702531187e-07 364 56 11 0.196428571428571 0.0302197802197802
GO:BP GO:0045088 regulation of innate immune response 2.94017312566929e-07 309 137 15 0.109489051094891 0.0485436893203883
GO:BP GO:0052126 movement in host environment 2.94017312566929e-07 177 87 10 0.114942528735632 0.0564971751412429
GO:BP GO:0046631 alpha-beta T cell activation 2.95190792967211e-07 155 128 11 0.0859375 0.0709677419354839
GO:BP GO:0002700 regulation of production of molecular mediator of immune response 3.41590910646295e-07 148 11 5 0.454545454545455 0.0337837837837838
GO:BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 3.44513169140229e-07 96 32 6 0.1875 0.0625
GO:BP GO:0002705 positive regulation of leukocyte mediated immunity 3.50739532881877e-07 122 67 8 0.119402985074627 0.0655737704918033
GO:BP GO:0010628 positive regulation of gene expression 4.15668528271893e-07 1160 26 12 0.461538461538462 0.0103448275862069
GO:BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 4.32750470536717e-07 100 32 6 0.1875 0.06
GO:BP GO:0002253 activation of immune response 5.24378165162116e-07 568 69 14 0.202898550724638 0.0246478873239437
GO:BP GO:0002429 immune response-activating cell surface receptor signaling pathway 5.42634699228082e-07 477 69 13 0.188405797101449 0.0272536687631027
GO:BP GO:0002757 immune response-activating signal transduction 5.42634699228082e-07 477 69 13 0.188405797101449 0.0272536687631027
GO:BP GO:0050851 antigen receptor-mediated signaling pathway 5.55438864996119e-07 323 67 11 0.164179104477612 0.0340557275541796
GO:BP GO:0006810 transport 6.4283676940365e-07 5224 102 56 0.549019607843137 0.0107197549770291
GO:BP GO:0050671 positive regulation of lymphocyte proliferation 6.66763882413974e-07 141 25 6 0.24 0.0425531914893617
GO:BP GO:0032946 positive regulation of mononuclear cell proliferation 6.91483887956828e-07 142 25 6 0.24 0.0422535211267606
GO:BP GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 8.72188778059383e-07 111 83 8 0.0963855421686747 0.0720720720720721
GO:BP GO:0042269 regulation of natural killer cell mediated cytotoxicity 8.99000918934802e-07 41 4 3 0.75 0.0731707317073171
GO:BP GO:0031341 regulation of cell killing 9.33861350042296e-07 93 100 8 0.08 0.0860215053763441
GO:BP GO:0001910 regulation of leukocyte mediated cytotoxicity 9.50733926567433e-07 74 49 6 0.122448979591837 0.0810810810810811
GO:BP GO:0046596 regulation of viral entry into host cell 9.70793344546167e-07 43 85 6 0.0705882352941176 0.13953488372093
GO:BP GO:0070841 inclusion body assembly 9.70793344546167e-07 24 28 4 0.142857142857143 0.166666666666667
GO:BP GO:0002707 negative regulation of lymphocyte mediated immunity 1.01144754008061e-06 43 4 3 0.75 0.0697674418604651
GO:BP GO:0002521 leukocyte differentiation 1.11476983601937e-06 550 127 18 0.141732283464567 0.0327272727272727
GO:BP GO:0031329 regulation of cellular catabolic process 1.12716779712505e-06 866 83 18 0.216867469879518 0.0207852193995381
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 1.12716779712505e-06 512 69 13 0.188405797101449 0.025390625
GO:BP GO:0043067 regulation of programmed cell death 1.12716779712505e-06 1582 124 31 0.25 0.0195954487989886
GO:BP GO:0002695 negative regulation of leukocyte activation 1.12716779712505e-06 188 122 11 0.0901639344262295 0.0585106382978723
GO:BP GO:0098609 cell-cell adhesion 1.12716779712505e-06 894 137 24 0.175182481751825 0.0268456375838926
GO:BP GO:0022610 biological adhesion 1.12716779712505e-06 1499 144 33 0.229166666666667 0.0220146764509673
GO:BP GO:0002715 regulation of natural killer cell mediated immunity 1.12716779712505e-06 45 4 3 0.75 0.0666666666666667
GO:BP GO:0002764 immune response-regulating signaling pathway 1.1889952153187e-06 515 69 13 0.188405797101449 0.0252427184466019
GO:BP GO:0043620 regulation of DNA-templated transcription in response to stress 1.20545034771662e-06 117 83 8 0.0963855421686747 0.0683760683760684
GO:BP GO:0002449 lymphocyte mediated immunity 1.25692556595831e-06 354 67 11 0.164179104477612 0.0310734463276836
GO:BP GO:0045071 negative regulation of viral genome replication 1.34835973768335e-06 54 72 6 0.0833333333333333 0.111111111111111
GO:BP GO:0002698 negative regulation of immune effector process 1.40980243955492e-06 125 7 4 0.571428571428571 0.032
GO:BP GO:0048522 positive regulation of cellular process 1.47017269805016e-06 5757 72 45 0.625 0.00781657113079729
GO:BP GO:0002706 regulation of lymphocyte mediated immunity 1.56019546818364e-06 151 67 8 0.119402985074627 0.0529801324503311
GO:BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.57907061697639e-06 363 67 11 0.164179104477612 0.0303030303030303
GO:BP GO:0002221 pattern recognition receptor signaling pathway 1.59408272686246e-06 213 67 9 0.134328358208955 0.0422535211267606
GO:BP GO:0051234 establishment of localization 1.59878788667492e-06 5372 102 56 0.549019607843137 0.0104244229337305
GO:BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.6087535054789e-06 152 67 8 0.119402985074627 0.0526315789473684
GO:BP GO:0035456 response to interferon-beta 1.62759520113492e-06 30 26 4 0.153846153846154 0.133333333333333
GO:BP GO:0046651 lymphocyte proliferation 1.70926077939957e-06 294 122 13 0.10655737704918 0.0442176870748299
GO:BP GO:0006457 protein folding 1.71069627175408e-06 225 132 12 0.0909090909090909 0.0533333333333333
GO:BP GO:0051250 negative regulation of lymphocyte activation 1.81427955758595e-06 156 122 10 0.0819672131147541 0.0641025641025641
GO:BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 1.81427955758595e-06 291 124 13 0.104838709677419 0.0446735395189003
GO:BP GO:0051701 biological process involved in interaction with host 1.87154315941946e-06 221 87 10 0.114942528735632 0.0452488687782805
GO:BP GO:0032943 mononuclear cell proliferation 1.87587226088057e-06 297 122 13 0.10655737704918 0.0437710437710438
GO:BP GO:0046635 positive regulation of alpha-beta T cell activation 1.9558750501317e-06 67 32 5 0.15625 0.0746268656716418
GO:BP GO:0030162 regulation of proteolysis 1.97351278545606e-06 752 43 12 0.27906976744186 0.0159574468085106
GO:BP GO:0045648 positive regulation of erythrocyte differentiation 2.03885623964858e-06 32 26 4 0.153846153846154 0.125
GO:BP GO:0140546 defense response to symbiont 2.05393391575735e-06 267 56 9 0.160714285714286 0.0337078651685393
GO:BP GO:0051607 defense response to virus 2.05393391575735e-06 267 56 9 0.160714285714286 0.0337078651685393
GO:BP GO:0052372 modulation by symbiont of entry into host 2.07065430765951e-06 50 85 6 0.0705882352941176 0.12
GO:BP GO:1903901 negative regulation of viral life cycle 2.10761753301222e-06 26 85 5 0.0588235294117647 0.192307692307692
GO:BP GO:0072593 reactive oxygen species metabolic process 2.20631877238261e-06 290 127 13 0.102362204724409 0.0448275862068966
GO:BP GO:0042981 regulation of apoptotic process 2.20751223700584e-06 1549 124 30 0.241935483870968 0.0193673337637185
GO:BP GO:0051085 chaperone cofactor-dependent protein refolding 2.36004279227353e-06 31 28 4 0.142857142857143 0.129032258064516
GO:BP GO:0042267 natural killer cell mediated cytotoxicity 2.56421078650682e-06 62 4 3 0.75 0.0483870967741935
GO:BP GO:0009894 regulation of catabolic process 2.58698829267743e-06 1033 83 19 0.228915662650602 0.0183930300096805
GO:BP GO:0031396 regulation of protein ubiquitination 2.90636457542537e-06 211 96 10 0.104166666666667 0.0473933649289099
GO:BP GO:0007155 cell adhesion 2.90636457542537e-06 1492 144 32 0.222222222222222 0.0214477211796247
GO:BP GO:0002228 natural killer cell mediated immunity 2.90706734259354e-06 65 4 3 0.75 0.0461538461538462
GO:BP GO:0002819 regulation of adaptive immune response 2.97857906325519e-06 167 67 8 0.119402985074627 0.0479041916167665
GO:BP GO:0001909 leukocyte mediated cytotoxicity 2.98667874334088e-06 107 144 9 0.0625 0.0841121495327103
GO:BP GO:0045824 negative regulation of innate immune response 3.00421901397409e-06 66 4 3 0.75 0.0454545454545455
GO:BP GO:0048519 negative regulation of biological process 3.02005320924957e-06 5757 29 23 0.793103448275862 0.00399513635574084
GO:BP GO:0050866 negative regulation of cell activation 3.02005320924957e-06 211 122 11 0.0901639344262295 0.0521327014218009
GO:BP GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway 3.0369162331096e-06 11 20 3 0.15 0.272727272727273
GO:BP GO:0001959 regulation of cytokine-mediated signaling pathway 3.15034409741312e-06 184 26 6 0.230769230769231 0.0326086956521739
GO:BP GO:0035556 intracellular signal transduction 3.17307497881944e-06 2772 46 22 0.478260869565217 0.00793650793650794
GO:BP GO:0008219 cell death 3.27610000649717e-06 2292 127 38 0.299212598425197 0.0165794066317627
GO:BP GO:0009057 macromolecule catabolic process 3.46786595785842e-06 1468 56 18 0.321428571428571 0.0122615803814714
GO:BP GO:0042127 regulation of cell population proliferation 3.49387924853457e-06 1774 26 13 0.5 0.00732807215332582
GO:BP GO:0048872 homeostasis of number of cells 3.62887919158035e-06 261 31 7 0.225806451612903 0.0268199233716475
GO:BP GO:0001961 positive regulation of cytokine-mediated signaling pathway 3.73957692135852e-06 50 20 4 0.2 0.08
GO:BP GO:0002468 dendritic cell antigen processing and presentation 3.84971066631788e-06 14 74 4 0.0540540540540541 0.285714285714286
GO:BP GO:0051084 'de novo' posttranslational protein folding 4.00209230495411e-06 36 28 4 0.142857142857143 0.111111111111111
GO:BP GO:0009968 negative regulation of signal transduction 4.06207996328064e-06 1364 43 15 0.348837209302326 0.0109970674486804
GO:BP GO:0051241 negative regulation of multicellular organismal process 4.2018644271756e-06 1160 70 18 0.257142857142857 0.0155172413793103
GO:BP GO:0002702 positive regulation of production of molecular mediator of immune response 4.25760106031649e-06 100 11 4 0.363636363636364 0.04
GO:BP GO:0060759 regulation of response to cytokine stimulus 4.45622365452364e-06 197 26 6 0.230769230769231 0.0304568527918782
GO:BP GO:2001185 regulation of CD8-positive, alpha-beta T cell activation 4.4904021948831e-06 18 14 3 0.214285714285714 0.166666666666667
GO:BP GO:0006915 apoptotic process 4.59696058968123e-06 1990 124 34 0.274193548387097 0.0170854271356784
GO:BP GO:0006301 postreplication repair 4.59696058968123e-06 52 50 5 0.1 0.0961538461538462
GO:BP GO:0051179 localization 4.8586021887172e-06 6901 128 77 0.6015625 0.0111578032169251
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 5.01972183869148e-06 3483 26 17 0.653846153846154 0.00488084984209015
GO:BP GO:0006401 RNA catabolic process 5.19823356347294e-06 424 53 10 0.188679245283019 0.0235849056603774
GO:BP GO:0045619 regulation of lymphocyte differentiation 5.66420726905297e-06 180 122 10 0.0819672131147541 0.0555555555555556
GO:BP GO:0006458 'de novo' protein folding 5.85878146991768e-06 40 28 4 0.142857142857143 0.1
GO:BP GO:0030098 lymphocyte differentiation 5.85878146991768e-06 376 127 14 0.110236220472441 0.0372340425531915
GO:BP GO:0060760 positive regulation of response to cytokine stimulus 5.97231050766216e-06 57 20 4 0.2 0.0701754385964912
GO:BP GO:0006402 mRNA catabolic process 6.27167242837202e-06 384 46 9 0.195652173913043 0.0234375
GO:BP GO:0030099 myeloid cell differentiation 6.39287868178249e-06 428 31 8 0.258064516129032 0.0186915887850467
GO:BP GO:0045621 positive regulation of lymphocyte differentiation 6.39287868178249e-06 104 120 8 0.0666666666666667 0.0769230769230769
GO:BP GO:0043085 positive regulation of catalytic activity 6.73017952474905e-06 1418 28 12 0.428571428571429 0.00846262341325811
GO:BP GO:1903708 positive regulation of hemopoiesis 6.77102348106501e-06 157 143 10 0.0699300699300699 0.0636942675159236
GO:BP GO:1902107 positive regulation of leukocyte differentiation 6.77102348106501e-06 157 143 10 0.0699300699300699 0.0636942675159236
GO:BP GO:0043488 regulation of mRNA stability 6.93240830657001e-06 191 46 7 0.152173913043478 0.0366492146596859
GO:BP GO:0044265 cellular macromolecule catabolic process 7.01542192451958e-06 1231 62 17 0.274193548387097 0.0138099106417547
GO:BP GO:0090084 negative regulation of inclusion body assembly 7.59072269248596e-06 11 28 3 0.107142857142857 0.272727272727273
GO:BP GO:0030163 protein catabolic process 7.80513783182947e-06 974 69 16 0.231884057971014 0.0164271047227926
GO:BP GO:0012501 programmed cell death 7.92880872002921e-06 2143 124 35 0.282258064516129 0.0163322445170322
GO:BP GO:0045646 regulation of erythrocyte differentiation 7.92880872002921e-06 47 26 4 0.153846153846154 0.0851063829787234
GO:BP GO:0048518 positive regulation of biological process 8.3215092660352e-06 6363 72 46 0.638888888888889 0.00722929435800723
GO:BP GO:1902531 regulation of intracellular signal transduction 8.34185629689757e-06 1842 27 13 0.481481481481481 0.00705754614549403
GO:BP GO:0046634 regulation of alpha-beta T cell activation 8.59038146502344e-06 102 128 8 0.0625 0.0784313725490196
GO:BP GO:0007041 lysosomal transport 8.68926370581515e-06 111 12 4 0.333333333333333 0.036036036036036
GO:BP GO:1903320 regulation of protein modification by small protein conjugation or removal 8.75849666269173e-06 243 96 10 0.104166666666667 0.0411522633744856
GO:BP GO:0044093 positive regulation of molecular function 8.7715873504163e-06 1771 24 12 0.5 0.00677583286278938
GO:BP GO:0002832 negative regulation of response to biotic stimulus 8.7813313447656e-06 100 4 3 0.75 0.03
GO:BP GO:0010648 negative regulation of cell communication 9.18330391521755e-06 1468 43 15 0.348837209302326 0.0102179836512262
GO:BP GO:0043487 regulation of RNA stability 9.27064311914849e-06 201 46 7 0.152173913043478 0.0348258706467662
GO:BP GO:0023057 negative regulation of signaling 9.35667581531078e-06 1471 43 15 0.348837209302326 0.0101971447994562
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 9.45955305564025e-06 177 33 6 0.181818181818182 0.0338983050847458
GO:BP GO:0044257 cellular protein catabolic process 1.09302342116956e-05 813 115 19 0.165217391304348 0.023370233702337
GO:BP GO:0032103 positive regulation of response to external stimulus 1.1151977167421e-05 513 100 14 0.14 0.0272904483430799
GO:BP GO:0016567 protein ubiquitination 1.1570698182955e-05 892 96 18 0.1875 0.0201793721973094
GO:BP GO:0071356 cellular response to tumor necrosis factor 1.18005446583592e-05 306 46 8 0.173913043478261 0.0261437908496732
GO:BP GO:0035455 response to interferon-alpha 1.28931135668198e-05 23 16 3 0.1875 0.130434782608696
GO:BP GO:0045069 regulation of viral genome replication 1.31358544102041e-05 84 72 6 0.0833333333333333 0.0714285714285714
GO:BP GO:0061013 regulation of mRNA catabolic process 1.31358544102041e-05 213 46 7 0.152173913043478 0.0328638497652582
GO:BP GO:0036037 CD8-positive, alpha-beta T cell activation 1.35466775813065e-05 27 14 3 0.214285714285714 0.111111111111111
GO:BP GO:0048523 negative regulation of cellular process 1.38500975076862e-05 5139 29 21 0.724137931034483 0.00408639813193228
GO:BP GO:0009628 response to abiotic stimulus 1.38500975076862e-05 1261 85 20 0.235294117647059 0.0158604282315623
GO:BP GO:0051131 chaperone-mediated protein complex assembly 1.38500975076862e-05 21 69 4 0.0579710144927536 0.19047619047619
GO:BP GO:0051603 proteolysis involved in cellular protein catabolic process 1.43211779959309e-05 750 115 18 0.156521739130435 0.024
GO:BP GO:0009893 positive regulation of metabolic process 1.45771262702104e-05 3783 26 17 0.653846153846154 0.00449378799894264
GO:BP GO:0032760 positive regulation of tumor necrosis factor production 1.47107279795185e-05 88 17 4 0.235294117647059 0.0454545454545455
GO:BP GO:0002833 positive regulation of response to biotic stimulus 1.51680067496224e-05 250 100 10 0.1 0.04
GO:BP GO:0008283 cell population proliferation 1.5219341395135e-05 2054 26 13 0.5 0.00632911392405063
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 1.55509702478391e-05 236 43 7 0.162790697674419 0.0296610169491525
GO:BP GO:0009966 regulation of signal transduction 1.64434319407568e-05 3165 27 16 0.592592592592593 0.00505529225908373
GO:BP GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 1.64902804798375e-05 91 17 4 0.235294117647059 0.043956043956044
GO:BP GO:0001906 cell killing 1.67689978679043e-05 175 144 10 0.0694444444444444 0.0571428571428571
GO:BP GO:0042129 regulation of T cell proliferation 1.74340493725594e-05 176 58 7 0.120689655172414 0.0397727272727273
GO:BP GO:0030218 erythrocyte differentiation 1.77697740971392e-05 116 31 5 0.161290322580645 0.0431034482758621
GO:BP GO:0045637 regulation of myeloid cell differentiation 1.92442989851558e-05 263 26 6 0.230769230769231 0.0228136882129278
GO:BP GO:0052547 regulation of peptidase activity 1.9312097140112e-05 467 132 15 0.113636363636364 0.0321199143468951
GO:BP GO:0034612 response to tumor necrosis factor 1.9491689593723e-05 331 46 8 0.173913043478261 0.0241691842900302
GO:BP GO:0050794 regulation of cellular process 2.07167605929871e-05 11473 29 29 1 0.00252767366861327
GO:BP GO:0001818 negative regulation of cytokine production 2.11226445502848e-05 381 122 13 0.10655737704918 0.0341207349081365
GO:BP GO:2001233 regulation of apoptotic signaling pathway 2.23614811131643e-05 363 43 8 0.186046511627907 0.0220385674931129
GO:BP GO:0035966 response to topologically incorrect protein 2.31310903462377e-05 205 128 10 0.078125 0.0487804878048781
GO:BP GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 2.31310903462377e-05 100 17 4 0.235294117647059 0.04
GO:BP GO:0034101 erythrocyte homeostasis 2.39070552696174e-05 124 31 5 0.161290322580645 0.0403225806451613
GO:BP GO:0009967 positive regulation of signal transduction 2.39995794207525e-05 1598 24 11 0.458333333333333 0.00688360450563204
GO:BP GO:0046597 negative regulation of viral entry into host cell 2.40295957637358e-05 20 85 4 0.0470588235294118 0.2
GO:BP GO:0002224 toll-like receptor signaling pathway 2.4693136862624e-05 161 67 7 0.104477611940299 0.0434782608695652
GO:BP GO:0032501 multicellular organismal process 2.4693136862624e-05 7946 56 42 0.75 0.00528567832871885
GO:BP GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 2.4739042761701e-05 40 42 4 0.0952380952380952 0.1
GO:BP GO:0006508 proteolysis 2.48746251484639e-05 1836 132 32 0.242424242424242 0.0174291938997821
GO:BP GO:0030217 T cell differentiation 2.52762826592248e-05 260 127 11 0.0866141732283465 0.0423076923076923
GO:BP GO:0032680 regulation of tumor necrosis factor production 2.53105168017919e-05 163 127 9 0.0708661417322835 0.0552147239263804
GO:BP GO:0007034 vacuolar transport 2.68313464236268e-05 154 12 4 0.333333333333333 0.025974025974026
GO:BP GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 2.69386065342339e-05 41 42 4 0.0952380952380952 0.0975609756097561
GO:BP GO:0045582 positive regulation of T cell differentiation 2.71080443587277e-05 91 120 7 0.0583333333333333 0.0769230769230769
GO:BP GO:0032640 tumor necrosis factor production 2.76458032477905e-05 165 127 9 0.0708661417322835 0.0545454545454545
GO:BP GO:0050777 negative regulation of immune response 2.85301236152693e-05 157 4 3 0.75 0.0191082802547771
GO:BP GO:0045591 positive regulation of regulatory T cell differentiation 2.89117096648645e-05 17 107 4 0.0373831775700935 0.235294117647059
GO:BP GO:0010942 positive regulation of cell death 2.97166465218615e-05 684 120 17 0.141666666666667 0.0248538011695906
GO:BP GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 3.01593089885552e-05 167 127 9 0.0708661417322835 0.0538922155688623
GO:BP GO:0051246 regulation of protein metabolic process 3.04020634283933e-05 2704 98 33 0.336734693877551 0.0122041420118343
GO:BP GO:0010629 negative regulation of gene expression 3.05962332784233e-05 1460 72 19 0.263888888888889 0.013013698630137
GO:BP GO:1902949 positive regulation of tau-protein kinase activity 3.22350379514091e-05 8 69 3 0.0434782608695652 0.375
GO:BP GO:0032446 protein modification by small protein conjugation 3.2589680658726e-05 973 69 15 0.217391304347826 0.0154162384378212
GO:BP GO:0071706 tumor necrosis factor superfamily cytokine production 3.41840099688954e-05 170 127 9 0.0708661417322835 0.0529411764705882
GO:BP GO:0032268 regulation of cellular protein metabolic process 3.57903092183542e-05 2541 69 25 0.36231884057971 0.00983864620228257
GO:BP GO:0030154 cell differentiation 3.58566116783714e-05 4350 100 45 0.45 0.0103448275862069
GO:BP GO:0010468 regulation of gene expression 3.67058902086897e-05 5196 28 20 0.714285714285714 0.00384911470361817
GO:BP GO:0043068 positive regulation of programmed cell death 3.67058902086897e-05 621 120 16 0.133333333333333 0.0257648953301127
GO:BP GO:0006605 protein targeting 3.89947635761312e-05 441 80 11 0.1375 0.0249433106575964
GO:BP GO:0031349 positive regulation of defense response 4.01255061012879e-05 362 137 13 0.0948905109489051 0.0359116022099447
GO:BP GO:0045730 respiratory burst 4.20030160244835e-05 35 125 5 0.04 0.142857142857143
GO:BP GO:0042098 T cell proliferation 4.20030160244835e-05 205 58 7 0.120689655172414 0.0341463414634146
GO:BP GO:0002347 response to tumor cell 4.20030160244835e-05 26 22 3 0.136363636363636 0.115384615384615
GO:BP GO:0043367 CD4-positive, alpha-beta T cell differentiation 4.22301103108586e-05 85 51 5 0.0980392156862745 0.0588235294117647
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 4.36310394834884e-05 294 58 8 0.137931034482759 0.0272108843537415
GO:BP GO:1903426 regulation of reactive oxygen species biosynthetic process 4.61775096587058e-05 111 70 6 0.0857142857142857 0.0540540540540541
GO:BP GO:0019222 regulation of metabolic process 4.86350662570498e-05 7148 28 23 0.821428571428571 0.00321768326804701
GO:BP GO:0034655 nucleobase-containing compound catabolic process 5.03962829429154e-05 567 53 10 0.188679245283019 0.017636684303351
GO:BP GO:0032020 ISG15-protein conjugation 5.11209871000442e-05 6 115 3 0.0260869565217391 0.5
GO:BP GO:0033554 cellular response to stress 5.13332951225333e-05 2111 83 25 0.301204819277108 0.0118427285646613
GO:BP GO:0019730 antimicrobial humoral response 5.13332951225333e-05 145 5 3 0.6 0.0206896551724138
GO:BP GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 5.34266009969426e-05 107 20 4 0.2 0.0373831775700935
GO:BP GO:0008284 positive regulation of cell population proliferation 5.4145850868356e-05 982 26 9 0.346153846153846 0.00916496945010183
GO:BP GO:0019985 translesion synthesis 5.45312325244267e-05 42 50 4 0.08 0.0952380952380952
GO:BP GO:0002262 myeloid cell homeostasis 5.49038923270594e-05 151 31 5 0.161290322580645 0.033112582781457
GO:BP GO:0006979 response to oxidative stress 5.5231041790536e-05 466 79 11 0.139240506329114 0.0236051502145923
GO:BP GO:0048869 cellular developmental process 5.56974673439045e-05 4428 100 45 0.45 0.0101626016260163
GO:BP GO:1903362 regulation of cellular protein catabolic process 5.90189120007711e-05 257 69 8 0.115942028985507 0.0311284046692607
GO:BP GO:0010647 positive regulation of cell communication 5.90189120007711e-05 1777 24 11 0.458333333333333 0.00619020821609454
GO:BP GO:0023056 positive regulation of signaling 6.04902896353686e-05 1782 24 11 0.458333333333333 0.00617283950617284
GO:BP GO:0010646 regulation of cell communication 6.34866316371429e-05 3543 27 16 0.592592592592593 0.00451594693762348
GO:BP GO:0062208 positive regulation of pattern recognition receptor signaling pathway 6.3556397182998e-05 43 51 4 0.0784313725490196 0.0930232558139535
GO:BP GO:0006986 response to unfolded protein 6.38293130793195e-05 184 128 9 0.0703125 0.0489130434782609
GO:BP GO:0060255 regulation of macromolecule metabolic process 6.47255792432883e-05 6603 28 22 0.785714285714286 0.00333181887021051
GO:BP GO:2001198 regulation of dendritic cell differentiation 6.67462040677818e-05 12 58 3 0.0517241379310345 0.25
GO:BP GO:1901575 organic substance catabolic process 7.08398695818797e-05 2267 56 20 0.357142857142857 0.00882223202470225
GO:BP GO:0023051 regulation of signaling 7.13521082051895e-05 3578 27 16 0.592592592592593 0.00447177193963108
GO:BP GO:0019079 viral genome replication 7.28481611299504e-05 131 18 4 0.222222222222222 0.0305343511450382
GO:BP GO:0052548 regulation of endopeptidase activity 7.30936409665421e-05 437 43 8 0.186046511627907 0.0183066361556064
GO:BP GO:0045862 positive regulation of proteolysis 7.5954626934221e-05 378 24 6 0.25 0.0158730158730159
GO:BP GO:0050789 regulation of biological process 7.78717465518716e-05 12091 29 29 1 0.00239847820693077
GO:BP GO:0097190 apoptotic signaling pathway 7.80994418594491e-05 600 77 12 0.155844155844156 0.02
GO:BP GO:0046700 heterocycle catabolic process 7.93867305622619e-05 602 53 10 0.188679245283019 0.0166112956810631
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 8.22159062801329e-05 1477 24 10 0.416666666666667 0.00677048070412999
GO:BP GO:0035710 CD4-positive, alpha-beta T cell activation 8.22159062801329e-05 104 127 7 0.0551181102362205 0.0673076923076923
GO:BP GO:0043069 negative regulation of programmed cell death 8.54280970084059e-05 943 43 11 0.255813953488372 0.0116648992576882
GO:BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 8.54329072192356e-05 251 124 10 0.0806451612903226 0.0398406374501992
GO:BP GO:0044270 cellular nitrogen compound catabolic process 8.54329072192356e-05 608 53 10 0.188679245283019 0.0164473684210526
GO:BP GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 8.67457450453904e-05 221 24 5 0.208333333333333 0.0226244343891403
GO:BP GO:0072594 establishment of protein localization to organelle 8.71052047736746e-05 584 80 12 0.15 0.0205479452054795
GO:BP GO:1901565 organonitrogen compound catabolic process 8.71052047736746e-05 1358 62 16 0.258064516129032 0.0117820324005891
GO:BP GO:0031348 negative regulation of defense response 9.28148771233681e-05 246 4 3 0.75 0.0121951219512195
GO:BP GO:0065007 biological regulation 0.000100325711760159 12809 33 33 1 0.00257631352954954
GO:BP GO:0019941 modification-dependent protein catabolic process 0.00010229827898212 662 50 10 0.2 0.0151057401812689
GO:BP GO:0043065 positive regulation of apoptotic process 0.000102974799257782 604 120 15 0.125 0.0248344370860927
GO:BP GO:0019439 aromatic compound catabolic process 0.000103470401735504 623 53 10 0.188679245283019 0.0160513643659711
GO:BP GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 0.000107055262011819 131 20 4 0.2 0.0305343511450382
GO:BP GO:0050821 protein stabilization 0.000107055262011819 193 100 8 0.08 0.0414507772020725
GO:BP GO:0042102 positive regulation of T cell proliferation 0.000109091294136387 104 25 4 0.16 0.0384615384615385
GO:BP GO:1900034 regulation of cellular response to heat 0.00011483548434401 79 69 5 0.072463768115942 0.0632911392405063
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 0.00011483548434401 673 50 10 0.2 0.0148588410104012
GO:BP GO:0031399 regulation of protein modification process 0.000117495660487463 1671 27 11 0.407407407407407 0.00658288450029922
GO:BP GO:2000377 regulation of reactive oxygen species metabolic process 0.000120270144733666 203 70 7 0.1 0.0344827586206897
GO:BP GO:0045595 regulation of cell differentiation 0.000121927515831856 1679 70 19 0.271428571428571 0.01131625967838
GO:BP GO:0050868 negative regulation of T cell activation 0.000122136853801129 123 22 4 0.181818181818182 0.032520325203252
GO:BP GO:1903409 reactive oxygen species biosynthetic process 0.000122873956924178 135 70 6 0.0857142857142857 0.0444444444444444
GO:BP GO:0051247 positive regulation of protein metabolic process 0.000127809015385956 1564 24 10 0.416666666666667 0.00639386189258312
GO:BP GO:0010952 positive regulation of peptidase activity 0.000128681284705331 205 127 9 0.0708661417322835 0.0439024390243902
GO:BP GO:1902947 regulation of tau-protein kinase activity 0.000131519064996911 13 69 3 0.0434782608695652 0.230769230769231
GO:BP GO:0046632 alpha-beta T cell differentiation 0.000131519064996911 113 127 7 0.0551181102362205 0.0619469026548673
GO:BP GO:0000731 DNA synthesis involved in DNA repair 0.000131519064996911 54 50 4 0.08 0.0740740740740741
GO:BP GO:0060548 negative regulation of cell death 0.000133920511496713 1038 49 12 0.244897959183673 0.0115606936416185
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 0.000133920511496713 167 17 4 0.235294117647059 0.0239520958083832
GO:BP GO:1901361 organic cyclic compound catabolic process 0.000142951285913336 651 53 10 0.188679245283019 0.0153609831029186
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 0.000148200858548271 3241 50 22 0.44 0.00678802838630052
GO:BP GO:0070555 response to interleukin-1 0.000163164448364234 215 96 8 0.0833333333333333 0.0372093023255814
GO:BP GO:0009056 catabolic process 0.000168090670117083 2744 83 28 0.337349397590361 0.0102040816326531
GO:BP GO:0001666 response to hypoxia 0.000168090670117083 367 42 7 0.166666666666667 0.0190735694822888
GO:BP GO:0070498 interleukin-1-mediated signaling pathway 0.000172713295310017 105 96 6 0.0625 0.0571428571428571
GO:BP GO:0042176 regulation of protein catabolic process 0.000176517061701368 401 69 9 0.130434782608696 0.0224438902743142
GO:BP GO:2000026 regulation of multicellular organismal development 0.000179370051515178 1447 127 25 0.196850393700787 0.0172771250863856
GO:BP GO:0045597 positive regulation of cell differentiation 0.000183490414435321 879 144 20 0.138888888888889 0.0227531285551763
GO:BP GO:1903364 positive regulation of cellular protein catabolic process 0.000186792886798019 154 20 4 0.2 0.025974025974026
GO:BP GO:0050672 negative regulation of lymphocyte proliferation 0.000198875286169814 85 122 6 0.0491803278688525 0.0705882352941176
GO:BP GO:1903038 negative regulation of leukocyte cell-cell adhesion 0.00020149104889666 142 22 4 0.181818181818182 0.028169014084507
GO:BP GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 0.00020327517748824 32 32 3 0.09375 0.09375
GO:BP GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 0.000204516383540843 73 42 4 0.0952380952380952 0.0547945205479452
GO:BP GO:0032945 negative regulation of mononuclear cell proliferation 0.000210641441902076 86 122 6 0.0491803278688525 0.0697674418604651
GO:BP GO:0036293 response to decreased oxygen levels 0.000210800819578152 382 42 7 0.166666666666667 0.0183246073298429
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.000213343950790545 1037 23 8 0.347826086956522 0.0077145612343298
GO:BP GO:0007162 negative regulation of cell adhesion 0.000223653794376851 304 22 5 0.227272727272727 0.0164473684210526
GO:BP GO:2000379 positive regulation of reactive oxygen species metabolic process 0.000233132580186771 107 100 6 0.06 0.0560747663551402
GO:BP GO:2000058 regulation of ubiquitin-dependent protein catabolic process 0.000238150726802194 165 20 4 0.2 0.0242424242424242
GO:BP GO:0048731 system development 0.000239594572283194 5052 94 45 0.478723404255319 0.00890736342042755
GO:BP GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 0.000239830228007467 78 83 5 0.0602409638554217 0.0641025641025641
GO:BP GO:1903311 regulation of mRNA metabolic process 0.000242298990299546 356 46 7 0.152173913043478 0.0196629213483146
GO:BP GO:0062197 cellular response to chemical stress 0.000242298990299546 365 79 9 0.113924050632911 0.0246575342465753
GO:BP GO:0051092 positive regulation of NF-kappaB transcription factor activity 0.000242659977559695 162 67 6 0.0895522388059701 0.037037037037037
GO:BP GO:0070647 protein modification by small protein conjugation or removal 0.000251462212890639 1184 69 15 0.217391304347826 0.0126689189189189
GO:BP GO:0044248 cellular catabolic process 0.000255046161638677 2347 83 25 0.301204819277108 0.0106518960374947
GO:BP GO:0045589 regulation of regulatory T cell differentiation 0.000255046161638677 35 32 3 0.09375 0.0857142857142857
GO:BP GO:0031397 negative regulation of protein ubiquitination 0.000256541858561706 83 132 6 0.0454545454545455 0.072289156626506
GO:BP GO:0032757 positive regulation of interleukin-8 production 0.000273502615535523 58 20 3 0.15 0.0517241379310345
GO:BP GO:0022408 negative regulation of cell-cell adhesion 0.000284096660470586 194 58 6 0.103448275862069 0.0309278350515464
GO:BP GO:0070664 negative regulation of leukocyte proliferation 0.000292130334011187 92 122 6 0.0491803278688525 0.0652173913043478
GO:BP GO:0070482 response to oxygen levels 0.000303239475162071 408 42 7 0.166666666666667 0.017156862745098
GO:BP GO:0051094 positive regulation of developmental process 0.000319653142204166 1341 70 16 0.228571428571429 0.0119313944817301
GO:BP GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 0.000320018102951683 38 32 3 0.09375 0.0789473684210526
GO:BP GO:0045066 regulatory T cell differentiation 0.000320018102951683 38 32 3 0.09375 0.0789473684210526
GO:BP GO:0031647 regulation of protein stability 0.000333277438020957 300 100 9 0.09 0.03
GO:BP GO:0048513 animal organ development 0.000333359097762701 3672 94 36 0.382978723404255 0.00980392156862745
GO:BP GO:0002286 T cell activation involved in immune response 0.000341951935096056 112 32 4 0.125 0.0357142857142857
GO:BP GO:0032102 negative regulation of response to external stimulus 0.000343054323122044 406 4 3 0.75 0.00738916256157635
GO:BP GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 0.000343054323122044 63 20 3 0.15 0.0476190476190476
GO:BP GO:0031145 anaphase-promoting complex-dependent catabolic process 0.000343054323122044 85 83 5 0.0602409638554217 0.0588235294117647
GO:BP GO:0043066 negative regulation of apoptotic process 0.000352212366647633 921 43 10 0.232558139534884 0.01085776330076
GO:BP GO:0042026 protein refolding 0.000366754930056285 23 56 3 0.0535714285714286 0.130434782608696
GO:BP GO:0032879 regulation of localization 0.000371719723808728 2872 127 38 0.299212598425197 0.0132311977715877
GO:BP GO:0008285 negative regulation of cell population proliferation 0.000393805381053913 790 143 18 0.125874125874126 0.0227848101265823
GO:BP GO:0002532 production of molecular mediator involved in inflammatory response 0.000398366963410723 94 127 6 0.047244094488189 0.0638297872340425
GO:BP GO:0010950 positive regulation of endopeptidase activity 0.000400446895375531 187 127 8 0.062992125984252 0.0427807486631016
GO:BP GO:0009892 negative regulation of metabolic process 0.000402845074113142 3479 50 22 0.44 0.0063236562230526
GO:BP GO:0070106 interleukin-27-mediated signaling pathway 0.000406004939561147 11 127 3 0.0236220472440945 0.272727272727273
GO:BP GO:0070757 interleukin-35-mediated signaling pathway 0.000406004939561147 11 127 3 0.0236220472440945 0.272727272727273
GO:BP GO:0090594 inflammatory response to wounding 0.000406890839174225 14 98 3 0.0306122448979592 0.214285714285714
GO:BP GO:0016071 mRNA metabolic process 0.000411553485931385 874 46 10 0.217391304347826 0.011441647597254
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 0.000426823147491163 434 42 7 0.166666666666667 0.0161290322580645
GO:BP GO:0010467 gene expression 0.000426823147491163 6179 26 19 0.730769230769231 0.00307493121864379
GO:BP GO:0071347 cellular response to interleukin-1 0.000432004071709282 185 96 7 0.0729166666666667 0.0378378378378378
GO:BP GO:0031116 positive regulation of microtubule polymerization 0.00045666003929253 31 126 4 0.0317460317460317 0.129032258064516
GO:BP GO:0007275 multicellular organism development 0.000458395477589559 5613 43 26 0.604651162790698 0.00463210404418315
GO:BP GO:0046456 icosanoid biosynthetic process 0.000482397605462982 56 70 4 0.0571428571428571 0.0714285714285714
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 0.000495104723136429 655 50 9 0.18 0.0137404580152672
GO:BP GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.000497678246020081 35 41 3 0.0731707317073171 0.0857142857142857
GO:BP GO:1901099 negative regulation of signal transduction in absence of ligand 0.000497678246020081 35 41 3 0.0731707317073171 0.0857142857142857
GO:BP GO:0042592 homeostatic process 0.000500130373152783 1981 78 21 0.269230769230769 0.0106007067137809
GO:BP GO:0061136 regulation of proteasomal protein catabolic process 0.000500144150842365 186 42 5 0.119047619047619 0.0268817204301075
GO:BP GO:0002886 regulation of myeloid leukocyte mediated immunity 0.000505378393370195 54 144 5 0.0347222222222222 0.0925925925925926
GO:BP GO:0045580 regulation of T cell differentiation 0.000506176230793214 152 120 7 0.0583333333333333 0.0460526315789474
GO:BP GO:0034599 cellular response to oxidative stress 0.000512665993866077 316 79 8 0.10126582278481 0.0253164556962025
GO:BP GO:1903321 negative regulation of protein modification by small protein conjugation or removal 0.00052906983868185 96 132 6 0.0454545454545455 0.0625
GO:BP GO:0032613 interleukin-10 production 0.000536456111449936 62 127 5 0.0393700787401575 0.0806451612903226
GO:BP GO:1901214 regulation of neuron death 0.00054281337984491 323 100 9 0.09 0.0278637770897833
GO:BP GO:0048856 anatomical structure development 0.000551419334313102 6106 94 50 0.531914893617021 0.00818866688503112
GO:BP GO:0006959 humoral immune response 0.000588994256382654 384 22 5 0.227272727272727 0.0130208333333333
GO:BP GO:0065008 regulation of biological quality 0.000611633412503832 4131 100 40 0.4 0.00968288549987896
GO:BP GO:0034605 cellular response to heat 0.000621816086314054 118 69 5 0.072463768115942 0.0423728813559322
GO:BP GO:1903428 positive regulation of reactive oxygen species biosynthetic process 0.000649722425549254 62 69 4 0.0579710144927536 0.0645161290322581
GO:BP GO:0046638 positive regulation of alpha-beta T cell differentiation 0.00065688075383996 50 32 3 0.09375 0.06
GO:BP GO:0051248 negative regulation of protein metabolic process 0.00065688075383996 1151 69 14 0.202898550724638 0.0121633362293658
GO:BP GO:0009611 response to wounding 0.000661761716572884 674 101 13 0.128712871287129 0.0192878338278932
GO:BP GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 0.000690656823769288 51 32 3 0.09375 0.0588235294117647
GO:BP GO:0071897 DNA biosynthetic process 0.000690656823769288 195 69 6 0.0869565217391304 0.0307692307692308
GO:BP GO:0080135 regulation of cellular response to stress 0.000690656823769288 725 70 11 0.157142857142857 0.0151724137931034
GO:BP GO:0016064 immunoglobulin mediated immune response 0.000690656823769288 223 8 3 0.375 0.0134529147982063
GO:BP GO:0031112 positive regulation of microtubule polymerization or depolymerization 0.000691963063746328 35 126 4 0.0317460317460317 0.114285714285714
GO:BP GO:0032729 positive regulation of interferon-gamma production 0.000700867882431796 66 25 3 0.12 0.0454545454545455
GO:BP GO:0019724 B cell mediated immunity 0.00071443372791998 226 8 3 0.375 0.0132743362831858
GO:BP GO:0002724 regulation of T cell cytokine production 0.000747965321798758 33 51 3 0.0588235294117647 0.0909090909090909
GO:BP GO:0038093 Fc receptor signaling pathway 0.000759266622386462 238 83 7 0.0843373493975904 0.0294117647058824
GO:BP GO:0045732 positive regulation of protein catabolic process 0.000805875141983062 237 20 4 0.2 0.0168776371308017
GO:BP GO:0032502 developmental process 0.000822173717584584 6628 102 56 0.549019607843137 0.00844900422450211
GO:BP GO:0010498 proteasomal protein catabolic process 0.000834769591191366 491 42 7 0.166666666666667 0.0142566191446029
GO:BP GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 0.000841639991724419 108 43 4 0.0930232558139535 0.037037037037037
GO:BP GO:0002888 positive regulation of myeloid leukocyte mediated immunity 0.00085468094206442 18 100 3 0.03 0.166666666666667
GO:BP GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 0.000865026411810388 90 20 3 0.15 0.0333333333333333
GO:BP GO:0060334 regulation of interferon-gamma-mediated signaling pathway 0.000875175085119798 26 69 3 0.0434782608695652 0.115384615384615
GO:BP GO:0060330 regulation of response to interferon-gamma 0.000875175085119798 26 69 3 0.0434782608695652 0.115384615384615
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.00087667850148812 549 27 6 0.222222222222222 0.0109289617486339
GO:BP GO:0045428 regulation of nitric oxide biosynthetic process 0.000881922868021664 68 69 4 0.0579710144927536 0.0588235294117647
GO:BP GO:0032673 regulation of interleukin-4 production 0.000885289516174653 31 58 3 0.0517241379310345 0.0967741935483871
GO:BP GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.000898401279390212 44 41 3 0.0731707317073171 0.0681818181818182
GO:BP GO:0051881 regulation of mitochondrial membrane potential 0.000907415238957196 74 64 4 0.0625 0.0540540540540541
GO:BP GO:0002369 T cell cytokine production 0.000938612430172117 36 51 3 0.0588235294117647 0.0833333333333333
GO:BP GO:0002437 inflammatory response to antigenic stimulus 0.000958618330276971 65 74 4 0.0540540540540541 0.0615384615384615
GO:BP GO:0032633 interleukin-4 production 0.00096173026175302 32 58 3 0.0517241379310345 0.09375
GO:BP GO:0080164 regulation of nitric oxide metabolic process 0.000969187587098133 70 69 4 0.0579710144927536 0.0571428571428571
GO:BP GO:0045184 establishment of protein localization 0.000975583698388073 2035 80 21 0.2625 0.0103194103194103
GO:BP GO:0002285 lymphocyte activation involved in immune response 0.00104080706835577 190 49 5 0.102040816326531 0.0263157894736842
GO:BP GO:0032677 regulation of interleukin-8 production 0.0011083913945345 99 20 3 0.15 0.0303030303030303
GO:BP GO:0030574 collagen catabolic process 0.0011083913945345 47 107 4 0.0373831775700935 0.0851063829787234
GO:BP GO:0031400 negative regulation of protein modification process 0.00112533281584209 578 27 6 0.222222222222222 0.0103806228373702
GO:BP GO:0032675 regulation of interleukin-6 production 0.00119518499871191 168 127 7 0.0551181102362205 0.0416666666666667
GO:BP GO:0070997 neuron death 0.00122151503656514 365 100 9 0.09 0.0246575342465753
GO:BP GO:0006886 intracellular protein transport 0.00122151503656514 1186 80 15 0.1875 0.0126475548060708
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.00125658480668488 1082 69 13 0.188405797101449 0.0120147874306839
GO:BP GO:0051336 regulation of hydrolase activity 0.00125658480668488 1321 43 11 0.255813953488372 0.00832702498107494
GO:BP GO:0045089 positive regulation of innate immune response 0.00125798606879528 216 100 7 0.07 0.0324074074074074
GO:BP GO:0032637 interleukin-8 production 0.00125908168965612 104 20 3 0.15 0.0288461538461538
GO:BP GO:0009617 response to bacterium 0.00127029165090363 743 22 6 0.272727272727273 0.00807537012113055
GO:BP GO:0032635 interleukin-6 production 0.00135190009114527 172 127 7 0.0551181102362205 0.0406976744186047
GO:BP GO:0042093 T-helper cell differentiation 0.00135349711820519 66 32 3 0.09375 0.0454545454545455
GO:BP GO:0050793 regulation of developmental process 0.00137464805368236 2605 70 22 0.314285714285714 0.00844529750479846
GO:BP GO:0062207 regulation of pattern recognition receptor signaling pathway 0.00138535739806825 108 20 3 0.15 0.0277777777777778
GO:BP GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 0.00140045140695175 67 32 3 0.09375 0.0447761194029851
GO:BP GO:0008637 apoptotic mitochondrial changes 0.00140476824456581 126 43 4 0.0930232558139535 0.0317460317460317
GO:BP GO:0009719 response to endogenous stimulus 0.00143640563888274 1683 78 18 0.230769230769231 0.0106951871657754
GO:BP GO:0046637 regulation of alpha-beta T cell differentiation 0.00145069590675883 68 32 3 0.09375 0.0441176470588235
GO:BP GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 0.00145069590675883 68 32 3 0.09375 0.0441176470588235
GO:BP GO:0002287 alpha-beta T cell activation involved in immune response 0.00150701160476112 69 32 3 0.09375 0.0434782608695652
GO:BP GO:0002293 alpha-beta T cell differentiation involved in immune response 0.00150701160476112 69 32 3 0.09375 0.0434782608695652
GO:BP GO:1901800 positive regulation of proteasomal protein catabolic process 0.00150787621213875 112 20 3 0.15 0.0267857142857143
GO:BP GO:0002861 regulation of inflammatory response to antigenic stimulus 0.00151012164771435 33 67 3 0.0447761194029851 0.0909090909090909
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 0.00154581584606467 240 43 5 0.116279069767442 0.0208333333333333
GO:BP GO:0032816 positive regulation of natural killer cell activation 0.0016363268042712 23 100 3 0.03 0.130434782608696
GO:BP GO:0006809 nitric oxide biosynthetic process 0.0016504338453931 82 69 4 0.0579710144927536 0.0487804878048781
GO:BP GO:0006909 phagocytosis 0.00165693093360784 387 144 11 0.0763888888888889 0.0284237726098191
GO:BP GO:0002292 T cell differentiation involved in immune response 0.00186115518643685 75 32 3 0.09375 0.04
GO:BP GO:0075733 intracellular transport of virus 0.00186216038364858 57 42 3 0.0714285714285714 0.0526315789473684
GO:BP GO:0042742 defense response to bacterium 0.00199462852300454 349 18 4 0.222222222222222 0.0114613180515759
GO:BP GO:0071705 nitrogen compound transport 0.00200588667068011 2322 80 22 0.275 0.00947459086993971
GO:BP GO:0042113 B cell activation 0.00200588667068011 330 19 4 0.210526315789474 0.0121212121212121
GO:BP GO:0046209 nitric oxide metabolic process 0.00200609610599732 87 69 4 0.0579710144927536 0.0459770114942529
GO:BP GO:0051091 positive regulation of DNA-binding transcription factor activity 0.00201884179419985 270 23 4 0.173913043478261 0.0148148148148148
GO:BP GO:0002755 MyD88-dependent toll-like receptor signaling pathway 0.00202401293652385 37 67 3 0.0447761194029851 0.0810810810810811
GO:BP GO:0050864 regulation of B cell activation 0.00202405867622742 194 122 7 0.0573770491803279 0.0360824742268041
GO:BP GO:1903573 negative regulation of response to endoplasmic reticulum stress 0.0020336848880501 46 132 4 0.0303030303030303 0.0869565217391304
GO:BP GO:0009408 response to heat 0.00204657592465573 159 69 5 0.072463768115942 0.0314465408805031
GO:BP GO:0042886 amide transport 0.00206182962229183 2007 80 20 0.25 0.00996512207274539
GO:BP GO:2001057 reactive nitrogen species metabolic process 0.00206182962229183 88 69 4 0.0579710144927536 0.0454545454545455
GO:BP GO:0001836 release of cytochrome c from mitochondria 0.00215128407198673 59 43 3 0.0697674418604651 0.0508474576271186
GO:BP GO:0048010 vascular endothelial growth factor receptor signaling pathway 0.00217832262254545 98 63 4 0.0634920634920635 0.0408163265306122
GO:BP GO:0030888 regulation of B cell proliferation 0.00231766759840336 63 100 4 0.04 0.0634920634920635
GO:BP GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 0.0023412575781106 134 20 3 0.15 0.0223880597014925
GO:BP GO:0019538 protein metabolic process 0.0023412575781106 5808 69 36 0.521739130434783 0.00619834710743802
GO:BP GO:0016477 cell migration 0.00247042703618917 1649 127 24 0.188976377952756 0.0145542753183748
GO:BP GO:0046794 transport of virus 0.00247042703618917 64 42 3 0.0714285714285714 0.046875
GO:BP GO:0006954 inflammatory response 0.00250251876180276 794 127 15 0.118110236220472 0.0188916876574307
GO:BP GO:0031110 regulation of microtubule polymerization or depolymerization 0.00250396774475124 85 136 5 0.0367647058823529 0.0588235294117647
GO:BP GO:0032273 positive regulation of protein polymerization 0.0025490534919928 141 126 6 0.0476190476190476 0.0425531914893617
GO:BP GO:0040007 growth 0.00257034453770895 967 20 6 0.3 0.0062047569803516
GO:BP GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 0.00262440140819236 103 27 3 0.111111111111111 0.029126213592233
GO:BP GO:1902579 multi-organism localization 0.00264282957194494 66 42 3 0.0714285714285714 0.0454545454545455
GO:BP GO:0044766 multi-organism transport 0.00264282957194494 66 42 3 0.0714285714285714 0.0454545454545455
GO:BP GO:0033674 positive regulation of kinase activity 0.00264282957194494 608 69 9 0.130434782608696 0.0148026315789474
GO:BP GO:0097028 dendritic cell differentiation 0.00267882801223984 48 58 3 0.0517241379310345 0.0625
GO:BP GO:0000165 MAPK cascade 0.00269643124898 935 46 9 0.195652173913043 0.00962566844919786
GO:BP GO:0002377 immunoglobulin production 0.00270896133892192 99 67 4 0.0597014925373134 0.0404040404040404
GO:BP GO:0043410 positive regulation of MAPK cascade 0.00270896133892192 539 23 5 0.217391304347826 0.00927643784786642
GO:BP GO:0051882 mitochondrial depolarization 0.00274409056089983 23 124 3 0.0241935483870968 0.130434782608696
GO:BP GO:0031113 regulation of microtubule polymerization 0.00274409056089983 53 126 4 0.0317460317460317 0.0754716981132075
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 0.00294418733794582 159 43 4 0.0930232558139535 0.0251572327044025
GO:BP GO:0038034 signal transduction in absence of ligand 0.00296330316826497 71 41 3 0.0731707317073171 0.0422535211267606
GO:BP GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 0.00296330316826497 71 41 3 0.0731707317073171 0.0422535211267606
GO:BP GO:0006820 anion transport 0.00312065875990449 2889 81 25 0.308641975308642 0.00865351332641052
GO:BP GO:0015031 protein transport 0.0031617756562041 1929 80 19 0.2375 0.00984966303784344
GO:BP GO:1902106 negative regulation of leukocyte differentiation 0.00328310858446621 105 29 3 0.103448275862069 0.0285714285714286
GO:BP GO:0032731 positive regulation of interleukin-1 beta production 0.00337547340732141 56 127 4 0.031496062992126 0.0714285714285714
GO:BP GO:0044267 cellular protein metabolic process 0.00342958732610764 5229 69 33 0.478260869565217 0.00631095811818703
GO:BP GO:0045429 positive regulation of nitric oxide biosynthetic process 0.00348151599605605 45 69 3 0.0434782608695652 0.0666666666666667
GO:BP GO:0071704 organic substance metabolic process 0.00348151599605605 11326 58 48 0.827586206896552 0.0042380363764789
GO:BP GO:0051493 regulation of cytoskeleton organization 0.00348151599605605 531 136 12 0.0882352941176471 0.0225988700564972
GO:BP GO:0043549 regulation of kinase activity 0.00349227103682118 921 69 11 0.159420289855072 0.011943539630836
GO:BP GO:0045454 cell redox homeostasis 0.00356315272721997 58 125 4 0.032 0.0689655172413793
GO:BP GO:1903707 negative regulation of hemopoiesis 0.00357715281799637 109 29 3 0.103448275862069 0.0275229357798165
GO:BP GO:0032479 regulation of type I interferon production 0.00360211707202927 130 56 4 0.0714285714285714 0.0307692307692308
GO:BP GO:0032606 type I interferon production 0.00367926388453021 131 56 4 0.0714285714285714 0.0305343511450382
GO:BP GO:1904407 positive regulation of nitric oxide metabolic process 0.00367926388453021 46 69 3 0.0434782608695652 0.0652173913043478
GO:BP GO:0040008 regulation of growth 0.00367926388453021 681 20 5 0.25 0.00734214390602056
GO:BP GO:0019068 virion assembly 0.00372309215016152 40 80 3 0.0375 0.075
GO:BP GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 0.00384033563914841 77 42 3 0.0714285714285714 0.038961038961039
GO:BP GO:0007005 mitochondrion organization 0.00392492893683635 561 64 8 0.125 0.0142602495543672
GO:BP GO:0015833 peptide transport 0.00392570840401545 1971 80 19 0.2375 0.00963977676306443
GO:BP GO:0070169 positive regulation of biomineral tissue development 0.00400923756395327 47 70 3 0.0428571428571429 0.0638297872340425
GO:BP GO:0002218 activation of innate immune response 0.00401559998157245 144 137 6 0.0437956204379562 0.0416666666666667
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 0.00403693635723173 2518 28 11 0.392857142857143 0.00436854646544877
GO:BP GO:0031331 positive regulation of cellular catabolic process 0.00403833922399873 393 20 4 0.2 0.0101781170483461
GO:BP GO:0007167 enzyme linked receptor protein signaling pathway 0.0040402942206382 1103 78 13 0.166666666666667 0.0117860380779692
GO:BP GO:1901564 organonitrogen compound metabolic process 0.00408830509668559 6792 99 53 0.535353535353535 0.00780329799764429
GO:BP GO:0032653 regulation of interleukin-10 production 0.0041397291126008 60 127 4 0.031496062992126 0.0666666666666667
GO:BP GO:0110151 positive regulation of biomineralization 0.00420020379463058 48 70 3 0.0428571428571429 0.0625
GO:BP GO:0050869 negative regulation of B cell activation 0.00428793842637012 34 100 3 0.03 0.0882352941176471
GO:BP GO:0010243 response to organonitrogen compound 0.00440820506897575 1085 132 18 0.136363636363636 0.0165898617511521
GO:BP GO:0031325 positive regulation of cellular metabolic process 0.0045437842132652 3274 26 12 0.461538461538462 0.00366524129505192
GO:BP GO:0045859 regulation of protein kinase activity 0.00456834896918875 809 69 10 0.144927536231884 0.0123609394313968
GO:BP GO:0045860 positive regulation of protein kinase activity 0.00457063760026664 534 69 8 0.115942028985507 0.0149812734082397
GO:BP GO:0032814 regulation of natural killer cell activation 0.00459548093430664 35 100 3 0.03 0.0857142857142857
GO:BP GO:0042554 superoxide anion generation 0.00459548093430664 35 100 3 0.03 0.0857142857142857
GO:BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 0.00464919258516956 185 43 4 0.0930232558139535 0.0216216216216216
GO:BP GO:0045577 regulation of B cell differentiation 0.00467349808111109 29 122 3 0.0245901639344262 0.103448275862069
GO:BP GO:1901700 response to oxygen-containing compound 0.004922800064922 1739 85 18 0.211764705882353 0.0103507763082231
GO:BP GO:0038095 Fc-epsilon receptor signaling pathway 0.00492701575098859 167 83 5 0.0602409638554217 0.029940119760479
GO:BP GO:0051345 positive regulation of hydrolase activity 0.00513127858156694 783 28 6 0.214285714285714 0.00766283524904215
GO:BP GO:1903579 negative regulation of ATP metabolic process 0.00517223546847475 29 127 3 0.0236220472440945 0.103448275862069
GO:BP GO:0001558 regulation of cell growth 0.00519938582388972 426 20 4 0.2 0.00938967136150235
GO:BP GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 0.00529420669903643 88 42 3 0.0714285714285714 0.0340909090909091
GO:BP GO:0032732 positive regulation of interleukin-1 production 0.00534429045209344 65 127 4 0.031496062992126 0.0615384615384615
GO:BP GO:0051347 positive regulation of transferase activity 0.00553015195083733 689 69 9 0.130434782608696 0.0130624092888244
GO:BP GO:0030308 negative regulation of cell growth 0.00554899663942812 192 20 3 0.15 0.015625
GO:BP GO:0006801 superoxide metabolic process 0.00559245384477234 67 125 4 0.032 0.0597014925373134
GO:BP GO:0002763 positive regulation of myeloid leukocyte differentiation 0.00570196891566551 59 143 4 0.027972027972028 0.0677966101694915
GO:BP GO:0051049 regulation of transport 0.00574147837242033 1809 70 16 0.228571428571429 0.00884466556108347
GO:BP GO:0042130 negative regulation of T cell proliferation 0.00595737113330025 70 122 4 0.0327868852459016 0.0571428571428571
GO:BP GO:0031323 regulation of cellular metabolic process 0.0059884253520926 6269 28 18 0.642857142857143 0.00287127133514117
GO:BP GO:2000736 regulation of stem cell differentiation 0.00603769403495984 115 127 5 0.0393700787401575 0.0434782608695652
GO:BP GO:0043170 macromolecule metabolic process 0.00612510139214245 9796 58 43 0.741379310344828 0.00438954675377705
GO:BP GO:0006690 icosanoid metabolic process 0.00621379573037997 124 70 4 0.0571428571428571 0.032258064516129
GO:BP GO:0009725 response to hormone 0.00626543595448446 921 64 10 0.15625 0.01085776330076
GO:BP GO:0008347 glial cell migration 0.00629647253243548 56 71 3 0.0422535211267606 0.0535714285714286
GO:BP GO:0042063 gliogenesis 0.00645963694613741 308 98 7 0.0714285714285714 0.0227272727272727
GO:BP GO:0071456 cellular response to hypoxia 0.00652487373052039 212 42 4 0.0952380952380952 0.0188679245283019
GO:BP GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 0.00671180135350063 129 69 4 0.0579710144927536 0.0310077519379845
GO:BP GO:0009896 positive regulation of catabolic process 0.00671251143317934 464 20 4 0.2 0.00862068965517241
GO:BP GO:0051338 regulation of transferase activity 0.00673379972142857 1035 23 6 0.260869565217391 0.00579710144927536
GO:BP GO:0045576 mast cell activation 0.00673379972142857 62 144 4 0.0277777777777778 0.0645161290322581
GO:BP GO:0010821 regulation of mitochondrion organization 0.00686993423426263 158 96 5 0.0520833333333333 0.0316455696202532
GO:BP GO:0031324 negative regulation of cellular metabolic process 0.00689076970833371 2719 28 11 0.392857142857143 0.00404560500183891
GO:BP GO:0034976 response to endoplasmic reticulum stress 0.0069131494174267 298 132 8 0.0606060606060606 0.0268456375838926
GO:BP GO:0007265 Ras protein signal transduction 0.00707381153925669 349 140 9 0.0642857142857143 0.0257879656160458
GO:BP GO:0014009 glial cell proliferation 0.00710243786385694 55 76 3 0.0394736842105263 0.0545454545454545
GO:BP GO:1902905 positive regulation of supramolecular fiber organization 0.00712036248045829 214 20 3 0.15 0.014018691588785
GO:BP GO:0050920 regulation of chemotaxis 0.00713051002872978 226 19 3 0.157894736842105 0.0132743362831858
GO:BP GO:0033365 protein localization to organelle 0.00715476691687995 1017 80 12 0.15 0.0117994100294985
GO:BP GO:0048863 stem cell differentiation 0.00715476691687995 258 88 6 0.0681818181818182 0.0232558139534884
GO:BP GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 0.00715476691687995 132 69 4 0.0579710144927536 0.0303030303030303
GO:BP GO:0002223 stimulatory C-type lectin receptor signaling pathway 0.00715476691687995 112 137 5 0.0364963503649635 0.0446428571428571
GO:BP GO:0033043 regulation of organelle organization 0.0072468284738644 1203 136 19 0.139705882352941 0.0157938487115544
GO:BP GO:1900015 regulation of cytokine production involved in inflammatory response 0.00724776008010789 72 127 4 0.031496062992126 0.0555555555555556
GO:BP GO:0030334 regulation of cell migration 0.00735925431447501 999 127 16 0.125984251968504 0.016016016016016
GO:BP GO:0036294 cellular response to decreased oxygen levels 0.00747335422310617 222 42 4 0.0952380952380952 0.018018018018018
GO:BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.00750110915253255 217 43 4 0.0930232558139535 0.0184331797235023
GO:BP GO:0002534 cytokine production involved in inflammatory response 0.00754390864490165 73 127 4 0.031496062992126 0.0547945205479452
GO:BP GO:0009266 response to temperature stimulus 0.007680636372078 228 69 5 0.072463768115942 0.0219298245614035
GO:BP GO:0006811 ion transport 0.00777417312132745 3661 81 28 0.345679012345679 0.00764818355640535
GO:BP GO:0006633 fatty acid biosynthetic process 0.00779573354788581 170 136 6 0.0441176470588235 0.0352941176470588
GO:BP GO:0031401 positive regulation of protein modification process 0.00781563537569014 1074 23 6 0.260869565217391 0.00558659217877095
GO:BP GO:0002220 innate immune response activating cell surface receptor signaling pathway 0.00784047545249073 115 137 5 0.0364963503649635 0.0434782608695652
GO:BP GO:0071702 organic substance transport 0.00784047545249073 2766 81 23 0.283950617283951 0.00831525668835864
GO:BP GO:0001932 regulation of protein phosphorylation 0.00785599982543972 1240 27 7 0.259259259259259 0.00564516129032258
GO:BP GO:0048870 cell motility 0.00792143029540141 1828 127 24 0.188976377952756 0.0131291028446389
GO:BP GO:0051674 localization of cell 0.00792143029540141 1828 127 24 0.188976377952756 0.0131291028446389
GO:BP GO:0016049 cell growth 0.00806159000959049 495 20 4 0.2 0.00808080808080808
GO:BP GO:0002758 innate immune response-activating signal transduction 0.00806159000959049 116 137 5 0.0364963503649635 0.0431034482758621
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 0.00809080307753421 223 43 4 0.0930232558139535 0.0179372197309417
GO:BP GO:0043408 regulation of MAPK cascade 0.00820846335060904 730 23 5 0.217391304347826 0.00684931506849315
GO:BP GO:0031109 microtubule polymerization or depolymerization 0.00837566407352711 118 136 5 0.0367647058823529 0.0423728813559322
GO:BP GO:0002573 myeloid leukocyte differentiation 0.0088348037851404 213 22 3 0.136363636363636 0.0140845070422535
GO:BP GO:0034622 cellular protein-containing complex assembly 0.00886754011906135 1107 23 6 0.260869565217391 0.00542005420054201
GO:BP GO:1901698 response to nitrogen compound 0.00889094336506841 1172 132 18 0.136363636363636 0.015358361774744
GO:BP GO:0042100 B cell proliferation 0.00889320835575031 98 100 4 0.04 0.0408163265306122
GO:BP GO:1901216 positive regulation of neuron death 0.00889320835575031 98 100 4 0.04 0.0408163265306122
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.00895117252521125 3083 26 11 0.423076923076923 0.00356795329224781
GO:BP GO:0070374 positive regulation of ERK1 and ERK2 cascade 0.00895117252521125 215 22 3 0.136363636363636 0.013953488372093
GO:BP GO:0051258 protein polymerization 0.00896191310914436 305 136 8 0.0588235294117647 0.0262295081967213
GO:BP GO:0007009 plasma membrane organization 0.00899992875670319 116 85 4 0.0470588235294118 0.0344827586206897
GO:BP GO:0046785 microtubule polymerization 0.00925055925472055 79 126 4 0.0317460317460317 0.0506329113924051
GO:BP GO:0071453 cellular response to oxygen levels 0.00932787258761719 240 42 4 0.0952380952380952 0.0166666666666667
GO:BP GO:0050729 positive regulation of inflammatory response 0.0094103237446867 142 117 5 0.0427350427350427 0.0352112676056338
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.00973911370288374 1227 79 13 0.164556962025316 0.0105949470252649
GO:BP GO:0046907 intracellular transport 0.00974818641376165 1767 97 19 0.195876288659794 0.010752688172043
GO:BP GO:0051090 regulation of DNA-binding transcription factor activity 0.00983367516178026 456 23 4 0.173913043478261 0.0087719298245614
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.00998086538611409 263 126 7 0.0555555555555556 0.026615969581749
GO:BP GO:0000209 protein polyubiquitination 0.0100240092196481 342 50 5 0.1 0.0146198830409357
GO:BP GO:1902622 regulation of neutrophil migration 0.0101409914739008 43 114 3 0.0263157894736842 0.0697674418604651
GO:BP GO:0051270 regulation of cellular component movement 0.0104014868778244 1141 127 17 0.133858267716535 0.0148992112182296
GO:BP GO:0030183 B cell differentiation 0.0104600500924919 140 122 5 0.040983606557377 0.0357142857142857
GO:BP GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0105344685056766 138 124 5 0.0403225806451613 0.036231884057971
GO:BP GO:0045926 negative regulation of growth 0.0106313992117583 255 20 3 0.15 0.0117647058823529
GO:BP GO:0006464 cellular protein modification process 0.0106331072342937 4041 24 12 0.5 0.00296956198960653
GO:BP GO:0036211 protein modification process 0.0106331072342937 4041 24 12 0.5 0.00296956198960653
GO:BP GO:0008152 metabolic process 0.0106331072342937 11827 58 48 0.827586206896552 0.00405851018855162
GO:BP GO:0007163 establishment or maintenance of cell polarity 0.0107713947055469 220 114 6 0.0526315789473684 0.0272727272727273
GO:BP GO:0080090 regulation of primary metabolic process 0.0110211348220368 6053 28 17 0.607142857142857 0.00280852469849661
GO:BP GO:0071495 cellular response to endogenous stimulus 0.0110395823162473 1422 78 14 0.179487179487179 0.00984528832630099
GO:BP GO:0006974 cellular response to DNA damage stimulus 0.0110504965939069 888 50 8 0.16 0.00900900900900901
GO:BP GO:0030336 negative regulation of cell migration 0.0111419898555046 353 15 3 0.2 0.0084985835694051
GO:BP GO:0071560 cellular response to transforming growth factor beta stimulus 0.0115147050359477 256 69 5 0.072463768115942 0.01953125
GO:BP GO:0072663 establishment of protein localization to peroxisome 0.0115352037912137 69 75 3 0.04 0.0434782608695652
GO:BP GO:0002761 regulation of myeloid leukocyte differentiation 0.0115352037912137 123 143 5 0.034965034965035 0.040650406504065
GO:BP GO:0072662 protein localization to peroxisome 0.0115352037912137 69 75 3 0.04 0.0434782608695652
GO:BP GO:0006625 protein targeting to peroxisome 0.0115352037912137 69 75 3 0.04 0.0434782608695652
GO:BP GO:2000145 regulation of cell motility 0.0119329604236139 1061 127 16 0.125984251968504 0.0150801131008483
GO:BP GO:0032480 negative regulation of type I interferon production 0.0120694303591737 46 115 3 0.0260869565217391 0.0652173913043478
GO:BP GO:0006521 regulation of cellular amino acid metabolic process 0.0122741173734469 64 83 3 0.036144578313253 0.046875
GO:BP GO:0098761 cellular response to interleukin-7 0.0122741173734469 42 127 3 0.0236220472440945 0.0714285714285714
GO:BP GO:0098760 response to interleukin-7 0.0122741173734469 42 127 3 0.0236220472440945 0.0714285714285714
GO:BP GO:2000146 negative regulation of cell motility 0.0123192609412755 369 15 3 0.2 0.00813008130081301
GO:BP GO:0071559 response to transforming growth factor beta 0.0124714110045523 262 69 5 0.072463768115942 0.0190839694656489
GO:BP GO:0010389 regulation of G2/M transition of mitotic cell cycle 0.0126663113226789 207 126 6 0.0476190476190476 0.0289855072463768
GO:BP GO:0051271 negative regulation of cellular component movement 0.01296304993943 377 15 3 0.2 0.00795755968169761
GO:BP GO:0043574 peroxisomal transport 0.0131748183792405 73 75 3 0.04 0.0410958904109589
GO:BP GO:0040011 locomotion 0.01318348477673 2028 127 25 0.196850393700787 0.01232741617357
GO:BP GO:0001774 microglial cell activation 0.0132632109323524 55 100 3 0.03 0.0545454545454545
GO:BP GO:0044106 cellular amine metabolic process 0.0132856021258883 163 34 3 0.0882352941176471 0.0184049079754601
GO:BP GO:0001934 positive regulation of protein phosphorylation 0.0134711322599924 840 23 5 0.217391304347826 0.00595238095238095
GO:BP GO:0019752 carboxylic acid metabolic process 0.0135031595944966 1024 36 7 0.194444444444444 0.0068359375
GO:BP GO:0065003 protein-containing complex assembly 0.014045021231152 1680 23 7 0.304347826086957 0.00416666666666667
GO:BP GO:0000302 response to reactive oxygen species 0.0140507215454764 237 79 5 0.0632911392405063 0.0210970464135021
GO:BP GO:0009308 amine metabolic process 0.0141053059929977 168 34 3 0.0882352941176471 0.0178571428571429
GO:BP GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.0142396196890485 136 42 3 0.0714285714285714 0.0220588235294118
GO:BP GO:1901215 negative regulation of neuron death 0.0145094628357448 213 127 6 0.047244094488189 0.028169014084507
GO:BP GO:0060326 cell chemotaxis 0.0145224429053777 310 19 3 0.157894736842105 0.00967741935483871
GO:BP GO:0051056 regulation of small GTPase mediated signal transduction 0.014793907926097 328 140 8 0.0571428571428571 0.024390243902439
GO:BP GO:0009888 tissue development 0.014793907926097 2107 92 20 0.217391304347826 0.0094921689606075
GO:BP GO:0040013 negative regulation of locomotion 0.014793907926097 401 15 3 0.2 0.00748129675810474
GO:BP GO:0051651 maintenance of location in cell 0.0147941694565325 223 122 6 0.0491803278688525 0.0269058295964126
GO:BP GO:0045444 fat cell differentiation 0.0148180107394144 229 83 5 0.0602409638554217 0.0218340611353712
GO:BP GO:0021954 central nervous system neuron development 0.0148383268838154 84 69 3 0.0434782608695652 0.0357142857142857
GO:BP GO:0008104 protein localization 0.0149373423407268 2770 131 32 0.244274809160305 0.0115523465703971
GO:BP GO:0042325 regulation of phosphorylation 0.0150385183108758 1431 27 7 0.259259259259259 0.00489168413696716
GO:BP GO:0030522 intracellular receptor signaling pathway 0.0151344158284202 284 42 4 0.0952380952380952 0.0140845070422535
GO:BP GO:0045778 positive regulation of ossification 0.0152622436582651 49 120 3 0.025 0.0612244897959184
GO:BP GO:0043412 macromolecule modification 0.0152737155733704 4257 24 12 0.5 0.00281888653981677
GO:BP GO:0043436 oxoacid metabolic process 0.0154129136281201 1057 36 7 0.194444444444444 0.00662251655629139
GO:BP GO:0043277 apoptotic cell clearance 0.0155359148103422 52 114 3 0.0263157894736842 0.0576923076923077
GO:BP GO:0040012 regulation of locomotion 0.0160724947273494 1104 127 16 0.125984251968504 0.0144927536231884
GO:BP GO:0030101 natural killer cell activation 0.0161421267141164 84 144 4 0.0277777777777778 0.0476190476190476
GO:BP GO:0016579 protein deubiquitination 0.0163120492205359 292 42 4 0.0952380952380952 0.0136986301369863
GO:BP GO:0043434 response to peptide hormone 0.0163120492205359 462 43 5 0.116279069767442 0.0108225108225108
GO:BP GO:0051452 intracellular pH reduction 0.0165690998115615 56 109 3 0.0275229357798165 0.0535714285714286
GO:BP GO:0032963 collagen metabolic process 0.0165788247447386 114 107 4 0.0373831775700935 0.0350877192982456
GO:BP GO:1902749 regulation of cell cycle G2/M phase transition 0.0166535243299503 223 126 6 0.0476190476190476 0.0269058295964126
GO:BP GO:0050727 regulation of inflammatory response 0.016676569064257 381 124 8 0.0645161290322581 0.020997375328084
GO:BP GO:0070507 regulation of microtubule cytoskeleton organization 0.0168314715453598 145 136 5 0.0367647058823529 0.0344827586206897
GO:BP GO:0006928 movement of cell or subcellular component 0.0171482548319602 2311 127 27 0.21259842519685 0.0116832540025963
GO:BP GO:0061919 process utilizing autophagic mechanism 0.0172069773922186 543 127 10 0.078740157480315 0.0184162062615101
GO:BP GO:0006914 autophagy 0.0172069773922186 543 127 10 0.078740157480315 0.0184162062615101
GO:BP GO:1902036 regulation of hematopoietic stem cell differentiation 0.017238935304566 75 83 3 0.036144578313253 0.04
GO:BP GO:0006082 organic acid metabolic process 0.0174191796996077 1090 36 7 0.194444444444444 0.00642201834862385
GO:BP GO:0038061 NIK/NF-kappaB signaling 0.0180058437777235 194 33 3 0.0909090909090909 0.0154639175257732
GO:BP GO:0010565 regulation of cellular ketone metabolic process 0.0180058437777235 194 33 3 0.0909090909090909 0.0154639175257732
GO:BP GO:0007031 peroxisome organization 0.0181756176303817 85 75 3 0.04 0.0352941176470588
GO:BP GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 0.0181756176303817 760 78 9 0.115384615384615 0.0118421052631579
GO:BP GO:0042327 positive regulation of phosphorylation 0.0184487422662521 927 23 5 0.217391304347826 0.00539374325782093
GO:BP GO:0045851 pH reduction 0.0184487422662521 59 109 3 0.0275229357798165 0.0508474576271186
GO:BP GO:0043300 regulation of leukocyte degranulation 0.018618215684707 45 144 3 0.0208333333333333 0.0666666666666667
GO:BP GO:0006626 protein targeting to mitochondrion 0.0186354582339244 101 64 3 0.046875 0.0297029702970297
GO:BP GO:0042060 wound healing 0.018842733722144 549 89 8 0.0898876404494382 0.0145719489981785
GO:BP GO:0043933 protein-containing complex subunit organization 0.0188867577057447 1963 32 9 0.28125 0.00458481915435558
GO:BP GO:0070167 regulation of biomineral tissue development 0.0188867577057447 93 70 3 0.0428571428571429 0.032258064516129
GO:BP GO:0000187 activation of MAPK activity 0.0189671316798903 156 42 3 0.0714285714285714 0.0192307692307692
GO:BP GO:0070646 protein modification by small protein removal 0.0190109267201255 310 42 4 0.0952380952380952 0.0129032258064516
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 0.0192191890083762 5848 28 16 0.571428571428571 0.0027359781121751
GO:BP GO:0002712 regulation of B cell mediated immunity 0.0192728912339787 54 122 3 0.0245901639344262 0.0555555555555556
GO:BP GO:0002889 regulation of immunoglobulin mediated immune response 0.0192728912339787 54 122 3 0.0245901639344262 0.0555555555555556
GO:BP GO:0032651 regulation of interleukin-1 beta production 0.019295278763428 102 127 4 0.031496062992126 0.0392156862745098
GO:BP GO:0048608 reproductive structure development 0.0193922930479741 429 69 6 0.0869565217391304 0.013986013986014
GO:BP GO:0032970 regulation of actin filament-based process 0.0197179834797195 406 121 8 0.0661157024793388 0.0197044334975369
GO:BP GO:0110149 regulation of biomineralization 0.0197186638661275 95 70 3 0.0428571428571429 0.0315789473684211
GO:BP GO:0070372 regulation of ERK1 and ERK2 cascade 0.0197260919665824 309 22 3 0.136363636363636 0.00970873786407767
GO:BP GO:0061458 reproductive system development 0.0198817220783667 432 69 6 0.0869565217391304 0.0138888888888889
GO:BP GO:0032271 regulation of protein polymerization 0.0203305113992137 236 126 6 0.0476190476190476 0.0254237288135593
GO:BP GO:0002244 hematopoietic progenitor cell differentiation 0.0203358501514867 172 122 5 0.040983606557377 0.0290697674418605
GO:BP GO:0043269 regulation of ion transport 0.0203383729536746 1379 70 12 0.171428571428571 0.00870195794053662
GO:BP GO:0033238 regulation of cellular amine metabolic process 0.020688332959901 82 83 3 0.036144578313253 0.0365853658536585
GO:BP GO:0032870 cellular response to hormone stimulus 0.020688332959901 645 62 7 0.112903225806452 0.0108527131782946
GO:BP GO:0034613 cellular protein localization 0.0210462327159283 2014 100 20 0.2 0.0099304865938431
GO:BP GO:0043303 mast cell degranulation 0.0213600107353921 48 144 3 0.0208333333333333 0.0625
GO:BP GO:0007264 small GTPase mediated signal transduction 0.0218155341804371 515 140 10 0.0714285714285714 0.0194174757281553
GO:BP GO:0042743 hydrogen peroxide metabolic process 0.0218904569231345 55 127 3 0.0236220472440945 0.0545454545454545
GO:BP GO:0070727 cellular macromolecule localization 0.0219587463915952 2024 100 20 0.2 0.00988142292490119
GO:BP GO:0032611 interleukin-1 beta production 0.0219816264507628 107 127 4 0.031496062992126 0.0373831775700935
GO:BP GO:0071407 cellular response to organic cyclic compound 0.0221343678119354 587 69 7 0.101449275362319 0.0119250425894378
GO:BP GO:0002448 mast cell mediated immunity 0.0222416636921419 49 144 3 0.0208333333333333 0.0612244897959184
GO:BP GO:0002279 mast cell activation involved in immune response 0.0222416636921419 49 144 3 0.0208333333333333 0.0612244897959184
GO:BP GO:0010608 posttranscriptional regulation of gene expression 0.022443750729427 896 46 7 0.152173913043478 0.0078125
GO:BP GO:0070371 ERK1 and ERK2 cascade 0.0226243070429688 329 22 3 0.136363636363636 0.00911854103343465
GO:BP GO:0032147 activation of protein kinase activity 0.0226561406495291 331 42 4 0.0952380952380952 0.0120845921450151
GO:BP GO:0072330 monocarboxylic acid biosynthetic process 0.0229032056952728 226 136 6 0.0441176470588235 0.0265486725663717
GO:BP GO:0030865 cortical cytoskeleton organization 0.0230803041173757 63 114 3 0.0263157894736842 0.0476190476190476
GO:BP GO:0061024 membrane organization 0.023121634152524 973 88 11 0.125 0.0113052415210689
GO:BP GO:0044070 regulation of anion transport 0.023121634152524 896 70 9 0.128571428571429 0.0100446428571429
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 0.023240216841339 1001 23 5 0.217391304347826 0.004995004995005
GO:BP GO:0045937 positive regulation of phosphate metabolic process 0.023240216841339 1001 23 5 0.217391304347826 0.004995004995005
GO:BP GO:0050900 leukocyte migration 0.0238432564820019 511 122 9 0.0737704918032787 0.0176125244618395
GO:BP GO:0007179 transforming growth factor beta receptor signaling pathway 0.0242380515379855 206 69 4 0.0579710144927536 0.0194174757281553
GO:BP GO:0060218 hematopoietic stem cell differentiation 0.0242979286892131 89 83 3 0.036144578313253 0.0337078651685393
GO:BP GO:1901532 regulation of hematopoietic progenitor cell differentiation 0.0242979286892131 89 83 3 0.036144578313253 0.0337078651685393
GO:BP GO:0051050 positive regulation of transport 0.0246952829973088 923 69 9 0.130434782608696 0.00975081256771398
GO:BP GO:0098869 cellular oxidant detoxification 0.0251901543269723 100 75 3 0.04 0.03
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.0255615159387637 387 20 3 0.15 0.00775193798449612
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.0255900944412407 366 114 7 0.0614035087719298 0.0191256830601093
GO:BP GO:0031960 response to corticosteroid 0.0256286201695115 165 46 3 0.0652173913043478 0.0181818181818182
GO:BP GO:0002526 acute inflammatory response 0.02571066183981 114 127 4 0.031496062992126 0.0350877192982456
GO:BP GO:0062012 regulation of small molecule metabolic process 0.02571066183981 447 33 4 0.121212121212121 0.00894854586129754
GO:BP GO:0007568 aging 0.0258026222671703 329 127 7 0.0551181102362205 0.0212765957446809
GO:BP GO:0019220 regulation of phosphate metabolic process 0.0264750073483223 1645 27 7 0.259259259259259 0.00425531914893617
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.0264750073483223 1645 27 7 0.259259259259259 0.00425531914893617
GO:BP GO:0009895 negative regulation of catabolic process 0.0276488254831448 321 132 7 0.053030303030303 0.0218068535825545
GO:BP GO:0070527 platelet aggregation 0.0276488254831448 64 122 3 0.0245901639344262 0.046875
GO:BP GO:0097435 supramolecular fiber organization 0.0278140784630263 734 136 12 0.0882352941176471 0.0163487738419619
GO:BP GO:0001676 long-chain fatty acid metabolic process 0.0278695270401366 112 70 3 0.0428571428571429 0.0267857142857143
GO:BP GO:0006468 protein phosphorylation 0.0281337396413452 1668 27 7 0.259259259259259 0.00419664268585132
GO:BP GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0.0281438488898616 95 83 3 0.036144578313253 0.0315789473684211
GO:BP GO:1901652 response to peptide 0.0281438488898616 551 43 5 0.116279069767442 0.00907441016333938
GO:BP GO:0010506 regulation of autophagy 0.0282289576076629 336 127 7 0.0551181102362205 0.0208333333333333
GO:BP GO:0032652 regulation of interleukin-1 production 0.0289681678102851 119 127 4 0.031496062992126 0.0336134453781513
GO:BP GO:0048678 response to axon injury 0.0290000684534947 80 100 3 0.03 0.0375
GO:BP GO:0033036 macromolecule localization 0.0291713601170153 3218 102 28 0.274509803921569 0.00870105655686762
GO:BP GO:0071363 cellular response to growth factor stimulus 0.0293294561173156 731 46 6 0.130434782608696 0.00820793433652531
GO:BP GO:1901570 fatty acid derivative biosynthetic process 0.0298537371333128 61 133 3 0.0225563909774436 0.0491803278688525
GO:BP GO:0051046 regulation of secretion 0.0298710401772607 647 52 6 0.115384615384615 0.00927357032457496
GO:BP GO:0033559 unsaturated fatty acid metabolic process 0.0299037879812317 116 70 3 0.0428571428571429 0.0258620689655172
GO:BP GO:0061515 myeloid cell development 0.0303181253191181 67 122 3 0.0245901639344262 0.0447761194029851
GO:BP GO:0000086 G2/M transition of mitotic cell cycle 0.0306779429360293 265 126 6 0.0476190476190476 0.0226415094339623
GO:BP GO:0007584 response to nutrient 0.0306806348511613 182 85 4 0.0470588235294118 0.021978021978022
GO:BP GO:0033273 response to vitamin 0.0317303129767276 98 85 3 0.0352941176470588 0.0306122448979592
GO:BP GO:0046034 ATP metabolic process 0.0319282767104839 314 27 3 0.111111111111111 0.00955414012738853
GO:BP GO:0030595 leukocyte chemotaxis 0.0327415554710356 227 70 4 0.0571428571428571 0.0176211453744493
GO:BP GO:1990748 cellular detoxification 0.0327415554710356 113 75 3 0.04 0.0265486725663717
GO:BP GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 0.0327415554710356 102 83 3 0.036144578313253 0.0294117647058824
GO:BP GO:0045861 negative regulation of proteolysis 0.0335428077937285 359 69 5 0.072463768115942 0.0139275766016713
GO:BP GO:0070848 response to growth factor 0.0336250299443826 759 46 6 0.130434782608696 0.00790513833992095
GO:BP GO:0032612 interleukin-1 production 0.0337261726161035 126 127 4 0.031496062992126 0.0317460317460317
GO:BP GO:0002685 regulation of leukocyte migration 0.0337271782576131 211 117 5 0.0427350427350427 0.023696682464455
GO:BP GO:0046394 carboxylic acid biosynthetic process 0.0345730722126137 330 136 7 0.0514705882352941 0.0212121212121212
GO:BP GO:0071375 cellular response to peptide hormone stimulus 0.0345730722126137 340 26 3 0.115384615384615 0.00882352941176471
GO:BP GO:0031330 negative regulation of cellular catabolic process 0.0347767621251977 262 132 6 0.0454545454545455 0.0229007633587786
GO:BP GO:1902115 regulation of organelle assembly 0.0354331400909262 192 85 4 0.0470588235294118 0.0208333333333333
GO:BP GO:0032880 regulation of protein localization 0.0354331400909262 922 100 11 0.11 0.0119305856832972
GO:BP GO:0042180 cellular ketone metabolic process 0.0360873715860966 271 33 3 0.0909090909090909 0.011070110701107
GO:BP GO:0010324 membrane invagination 0.0361876062012794 144 114 4 0.0350877192982456 0.0277777777777778
GO:BP GO:0032720 negative regulation of tumor necrosis factor production 0.0364792367513031 73 122 3 0.0245901639344262 0.0410958904109589
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.0364900061654052 540 126 9 0.0714285714285714 0.0166666666666667
GO:BP GO:0051048 negative regulation of secretion 0.036897837641062 176 51 3 0.0588235294117647 0.0170454545454545
GO:BP GO:1903034 regulation of response to wounding 0.0369806062070851 169 98 4 0.0408163265306122 0.0236686390532544
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.0370024901043095 460 20 3 0.15 0.00652173913043478
GO:BP GO:0097237 cellular response to toxic substance 0.0371880369681342 120 75 3 0.04 0.025
GO:BP GO:1901990 regulation of mitotic cell cycle phase transition 0.0372381945870569 451 126 8 0.0634920634920635 0.0177383592017738
GO:BP GO:0010035 response to inorganic substance 0.0372381945870569 575 119 9 0.0756302521008403 0.0156521739130435
GO:BP GO:0045598 regulation of fat cell differentiation 0.0376012725133277 139 120 4 0.0333333333333333 0.0287769784172662
GO:BP GO:0016053 organic acid biosynthetic process 0.0380434411311225 338 136 7 0.0514705882352941 0.0207100591715976
GO:BP GO:0038127 ERBB signaling pathway 0.0381071392745037 145 63 3 0.0476190476190476 0.0206896551724138
GO:BP GO:0060071 Wnt signaling pathway, planar cell polarity pathway 0.0381520031790784 110 83 3 0.036144578313253 0.0272727272727273
GO:BP GO:0072655 establishment of protein localization to mitochondrion 0.0382502515512567 143 64 3 0.046875 0.020979020979021
GO:BP GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 0.0382856489598266 75 122 3 0.0245901639344262 0.04
GO:BP GO:0044839 cell cycle G2/M phase transition 0.0384684000109322 283 126 6 0.0476190476190476 0.0212014134275618
GO:BP GO:0014070 response to organic cyclic compound 0.0398551066594948 967 85 10 0.117647058823529 0.0103412616339193
GO:BP GO:1902750 negative regulation of cell cycle G2/M phase transition 0.0403836985715134 113 83 3 0.036144578313253 0.0265486725663717
GO:BP GO:0006259 DNA metabolic process 0.0404157224827845 965 73 9 0.123287671232877 0.00932642487046632
GO:BP GO:0070585 protein localization to mitochondrion 0.0404977727839338 147 64 3 0.046875 0.0204081632653061
GO:BP GO:0090175 regulation of establishment of planar polarity 0.0410680489578513 114 83 3 0.036144578313253 0.0263157894736842
GO:BP GO:0043270 positive regulation of ion transport 0.0426308228610784 694 69 7 0.101449275362319 0.0100864553314121
GO:BP GO:0071216 cellular response to biotic stimulus 0.0428128086635255 238 74 4 0.0540540540540541 0.0168067226890756
GO:BP GO:0051453 regulation of intracellular pH 0.0432594409499682 89 109 3 0.0275229357798165 0.0337078651685393
GO:BP GO:0033135 regulation of peptidyl-serine phosphorylation 0.0434200552723214 146 121 4 0.0330578512396694 0.0273972602739726
GO:BP GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.0434200552723214 257 69 4 0.0579710144927536 0.0155642023346304
GO:BP GO:0043406 positive regulation of MAP kinase activity 0.0437575617490656 234 42 3 0.0714285714285714 0.0128205128205128
GO:BP GO:0030316 osteoclast differentiation 0.0440339595997262 98 100 3 0.03 0.0306122448979592
GO:BP GO:0001933 negative regulation of protein phosphorylation 0.0452789688839128 373 27 3 0.111111111111111 0.00804289544235925
GO:BP GO:0055085 transmembrane transport 0.0455901790301253 1635 143 21 0.146853146853147 0.0128440366972477
GO:BP GO:0006839 mitochondrial transport 0.0461713646457155 284 64 4 0.0625 0.0140845070422535
GO:BP GO:0098754 detoxification 0.0464853943806827 134 75 3 0.04 0.0223880597014925
GO:BP GO:0030335 positive regulation of cell migration 0.0470713695690148 567 127 9 0.0708661417322835 0.0158730158730159
GO:BP GO:0001890 placenta development 0.0473374603504828 147 69 3 0.0434782608695652 0.0204081632653061
GO:BP GO:0046578 regulation of Ras protein signal transduction 0.0487047234298204 199 140 5 0.0357142857142857 0.0251256281407035
GO:BP GO:0010639 negative regulation of organelle organization 0.0487482108510873 361 136 7 0.0514705882352941 0.0193905817174515
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0490186730291087 253 41 3 0.0731707317073171 0.0118577075098814
GO:BP GO:0030641 regulation of cellular pH 0.0494218120561467 95 109 3 0.0275229357798165 0.0315789473684211
GO:CC GO:0031410 cytoplasmic vesicle 6.5113366212955e-21 2424 102 55 0.53921568627451 0.0226897689768977
GO:CC GO:0097708 intracellular vesicle 6.5113366212955e-21 2428 102 55 0.53921568627451 0.0226523887973641
GO:CC GO:0031982 vesicle 6.4164004677443e-20 4055 131 79 0.603053435114504 0.019482120838471
GO:CC GO:0042611 MHC protein complex 1.08684895102203e-18 24 49 10 0.204081632653061 0.416666666666667
GO:CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 1.20534952994803e-18 25 49 10 0.204081632653061 0.4
GO:CC GO:0098553 lumenal side of endoplasmic reticulum membrane 1.20534952994803e-18 25 49 10 0.204081632653061 0.4
GO:CC GO:0098576 lumenal side of membrane 6.35594725642308e-18 33 102 12 0.117647058823529 0.363636363636364
GO:CC GO:0070062 extracellular exosome 1.2663460320219e-17 2176 129 55 0.426356589147287 0.0252757352941176
GO:CC GO:1903561 extracellular vesicle 5.75818878133419e-17 2261 98 47 0.479591836734694 0.0207872622733304
GO:CC GO:0043230 extracellular organelle 5.75818878133419e-17 2263 98 47 0.479591836734694 0.0207688908528502
GO:CC GO:0030666 endocytic vesicle membrane 2.65398947356479e-16 159 52 14 0.269230769230769 0.0880503144654088
GO:CC GO:0030139 endocytic vesicle 4.99156538897237e-16 306 131 23 0.175572519083969 0.0751633986928105
GO:CC GO:0005773 vacuole 4.99156538897237e-16 810 125 33 0.264 0.0407407407407407
GO:CC GO:0005764 lysosome 7.8502698906721e-16 712 125 31 0.248 0.0435393258426966
GO:CC GO:0000323 lytic vacuole 7.8502698906721e-16 712 125 31 0.248 0.0435393258426966
GO:CC GO:0012507 ER to Golgi transport vesicle membrane 5.62370465318312e-15 57 49 10 0.204081632653061 0.175438596491228
GO:CC GO:0012505 endomembrane system 2.04799553938803e-14 4640 133 76 0.571428571428571 0.0163793103448276
GO:CC GO:0005768 endosome 2.45957310612604e-14 987 98 30 0.306122448979592 0.0303951367781155
GO:CC GO:0042612 MHC class I protein complex 3.1279225588699e-13 8 4 4 1 0.5
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 4.75664814933701e-13 90 32 9 0.28125 0.1
GO:CC GO:0005774 vacuolar membrane 8.09735562449142e-13 441 118 22 0.186440677966102 0.0498866213151927
GO:CC GO:0010008 endosome membrane 1.0236539606407e-12 505 84 20 0.238095238095238 0.0396039603960396
GO:CC GO:0098588 bounding membrane of organelle 2.05030185892148e-12 2158 125 46 0.368 0.0213160333642261
GO:CC GO:0030141 secretory granule 3.48323536050113e-12 851 100 26 0.26 0.0305522914218566
GO:CC GO:0005615 extracellular space 3.49550766072871e-12 3594 104 53 0.509615384615385 0.0147468002225932
GO:CC GO:0005765 lysosomal membrane 4.43430222968306e-12 383 118 20 0.169491525423729 0.0522193211488251
GO:CC GO:0098852 lytic vacuole membrane 4.43430222968306e-12 383 118 20 0.169491525423729 0.0522193211488251
GO:CC GO:0045335 phagocytic vesicle 1.04788139923429e-11 137 131 14 0.106870229007634 0.102189781021898
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 5.7800990302058e-11 158 32 9 0.28125 0.0569620253164557
GO:CC GO:0030659 cytoplasmic vesicle membrane 8.41078521492482e-11 779 88 22 0.25 0.0282413350449294
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 8.45580003954327e-11 166 32 9 0.28125 0.0542168674698795
GO:CC GO:0012506 vesicle membrane 1.32710811721208e-10 800 88 22 0.25 0.0275
GO:CC GO:0030662 coated vesicle membrane 1.41772234513878e-10 177 32 9 0.28125 0.0508474576271186
GO:CC GO:0099503 secretory vesicle 1.49842585444977e-10 1020 100 26 0.26 0.0254901960784314
GO:CC GO:0005576 extracellular region 2.03619478958339e-10 4567 104 57 0.548076923076923 0.0124808408145391
GO:CC GO:0031090 organelle membrane 2.51097650678089e-10 3612 133 59 0.443609022556391 0.0163344407530454
GO:CC GO:0042613 MHC class II protein complex 5.25471418437354e-10 16 32 5 0.15625 0.3125
GO:CC GO:0030658 transport vesicle membrane 5.4767818850714e-10 209 32 9 0.28125 0.0430622009569378
GO:CC GO:0005770 late endosome 1.68825979820543e-09 275 98 14 0.142857142857143 0.0509090909090909
GO:CC GO:1904813 ficolin-1-rich granule lumen 2.34273167299309e-09 124 85 10 0.117647058823529 0.0806451612903226
GO:CC GO:0030670 phagocytic vesicle membrane 2.65672064300891e-09 76 4 4 1 0.0526315789473684
GO:CC GO:0055038 recycling endosome membrane 3.90038314285641e-09 84 4 4 1 0.0476190476190476
GO:CC GO:0071944 cell periphery 7.16640596875514e-09 6169 127 75 0.590551181102362 0.0121575620035662
GO:CC GO:0030133 transport vesicle 9.64779669949166e-09 414 32 10 0.3125 0.0241545893719807
GO:CC GO:0030135 coated vesicle 9.84738239902565e-09 295 32 9 0.28125 0.0305084745762712
GO:CC GO:0009986 cell surface 2.15436925956188e-08 899 69 18 0.260869565217391 0.0200222469410456
GO:CC GO:0031301 integral component of organelle membrane 2.74447345537643e-08 382 49 11 0.224489795918367 0.0287958115183246
GO:CC GO:0043202 lysosomal lumen 3.344147518287e-08 97 73 8 0.10958904109589 0.0824742268041237
GO:CC GO:0030669 clathrin-coated endocytic vesicle membrane 3.344147518287e-08 36 32 5 0.15625 0.138888888888889
GO:CC GO:0031901 early endosome membrane 4.35320149035351e-08 159 4 4 1 0.0251572327044025
GO:CC GO:0031300 intrinsic component of organelle membrane 5.69387223336881e-08 413 49 11 0.224489795918367 0.026634382566586
GO:CC GO:0055037 recycling endosome 8.22964489951092e-08 188 4 4 1 0.0212765957446809
GO:CC GO:0101002 ficolin-1-rich granule 8.33718036503489e-08 184 85 10 0.117647058823529 0.0543478260869565
GO:CC GO:0016020 membrane 8.9953557167181e-08 9838 127 97 0.763779527559055 0.00985972758690791
GO:CC GO:0005783 endoplasmic reticulum 1.40185843186516e-07 1982 111 33 0.297297297297297 0.0166498486377397
GO:CC GO:0005789 endoplasmic reticulum membrane 1.56402658502133e-07 1117 51 16 0.313725490196078 0.0143240823634736
GO:CC GO:0098827 endoplasmic reticulum subcompartment 1.63619704672469e-07 1122 51 16 0.313725490196078 0.0142602495543672
GO:CC GO:0005775 vacuolar lumen 1.73410034214124e-07 174 73 9 0.123287671232877 0.0517241379310345
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 1.95235786468213e-07 1139 51 16 0.313725490196078 0.0140474100087796
GO:CC GO:0045334 clathrin-coated endocytic vesicle 2.24254500134783e-07 54 32 5 0.15625 0.0925925925925926
GO:CC GO:0005737 cytoplasm 2.48887330105693e-07 11911 134 113 0.843283582089552 0.00948702879691042
GO:CC GO:0005886 plasma membrane 4.68470705594698e-07 5681 127 67 0.52755905511811 0.0117936982925541
GO:CC GO:0034774 secretory granule lumen 7.85153937957484e-07 320 99 12 0.121212121212121 0.0375
GO:CC GO:0043227 membrane-bounded organelle 8.34294906871694e-07 12858 144 125 0.868055555555556 0.00972157411728107
GO:CC GO:0060205 cytoplasmic vesicle lumen 8.70620406198119e-07 324 99 12 0.121212121212121 0.037037037037037
GO:CC GO:0098797 plasma membrane protein complex 8.71006607350805e-07 694 32 10 0.3125 0.0144092219020173
GO:CC GO:0031983 vesicle lumen 8.99826552595132e-07 326 99 12 0.121212121212121 0.0368098159509202
GO:CC GO:0031902 late endosome membrane 8.99826552595132e-07 140 80 8 0.1 0.0571428571428571
GO:CC GO:0005769 early endosome 1.03015715536144e-06 378 4 4 1 0.0105820105820106
GO:CC GO:0098552 side of membrane 1.04547084193286e-06 619 55 12 0.218181818181818 0.0193861066235864
GO:CC GO:0005794 Golgi apparatus 1.58595271666475e-06 1623 8 7 0.875 0.00431300061614294
GO:CC GO:0042470 melanosome 1.99593264518307e-06 105 119 8 0.0672268907563025 0.0761904761904762
GO:CC GO:0048770 pigment granule 1.99593264518307e-06 105 119 8 0.0672268907563025 0.0761904761904762
GO:CC GO:0048471 perinuclear region of cytoplasm 2.7514524434881e-06 735 92 16 0.173913043478261 0.0217687074829932
GO:CC GO:0032588 trans-Golgi network membrane 2.9692876849332e-06 94 32 5 0.15625 0.0531914893617021
GO:CC GO:0032991 protein-containing complex 4.07552471130386e-06 5548 26 20 0.769230769230769 0.00360490266762797
GO:CC GO:0098791 Golgi apparatus subcompartment 6.11531433659365e-06 885 123 20 0.16260162601626 0.0225988700564972
GO:CC GO:0043231 intracellular membrane-bounded organelle 6.57674228137957e-06 11296 144 113 0.784722222222222 0.0100035410764873
GO:CC GO:0030667 secretory granule membrane 6.76003318479993e-06 303 13 5 0.384615384615385 0.0165016501650165
GO:CC GO:0030665 clathrin-coated vesicle membrane 7.26993785515091e-06 114 32 5 0.15625 0.043859649122807
GO:CC GO:0031984 organelle subcompartment 7.85895616012514e-06 1773 133 31 0.233082706766917 0.0174844895657078
GO:CC GO:0098796 membrane protein complex 7.85895616012514e-06 1322 133 26 0.195488721804511 0.0196671709531014
GO:CC GO:0000139 Golgi membrane 9.61569166433268e-06 771 97 16 0.164948453608247 0.0207522697795071
GO:CC GO:0016234 inclusion body 1.28607193487053e-05 76 96 6 0.0625 0.0789473684210526
GO:CC GO:0001772 immunological synapse 3.10285218779666e-05 43 114 5 0.043859649122807 0.116279069767442
GO:CC GO:0030136 clathrin-coated vesicle 8.77969394676779e-05 193 32 5 0.15625 0.0259067357512953
GO:CC GO:0005766 primary lysosome 0.000119989529853931 154 144 8 0.0555555555555556 0.051948051948052
GO:CC GO:0042582 azurophil granule 0.000119989529853931 154 144 8 0.0555555555555556 0.051948051948052
GO:CC GO:0016235 aggresome 0.00014547317880689 35 96 4 0.0416666666666667 0.114285714285714
GO:CC GO:0043226 organelle 0.000226887883061444 14008 89 81 0.910112359550562 0.0057824100513992
GO:CC GO:0005802 trans-Golgi network 0.000286326584060702 250 32 5 0.15625 0.02
GO:CC GO:0043020 NADPH oxidase complex 0.000289571788951853 12 125 3 0.024 0.25
GO:CC GO:0005829 cytosol 0.000342342615392701 5303 144 62 0.430555555555556 0.0116914953799736
GO:CC GO:0043229 intracellular organelle 0.000376033997621835 12491 81 69 0.851851851851852 0.00552397726362981
GO:CC GO:0005767 secondary lysosome 0.000686117285889296 16 125 3 0.024 0.1875
GO:CC GO:0031968 organelle outer membrane 0.000749937256959939 227 68 6 0.0882352941176471 0.026431718061674
GO:CC GO:0019867 outer membrane 0.000778651548819509 229 68 6 0.0882352941176471 0.0262008733624454
GO:CC GO:0000502 proteasome complex 0.000896767487216427 66 83 4 0.0481927710843374 0.0606060606060606
GO:CC GO:1905369 endopeptidase complex 0.00115999880207186 72 33 3 0.0909090909090909 0.0416666666666667
GO:CC GO:0008180 COP9 signalosome 0.00120882227922057 35 69 3 0.0434782608695652 0.0857142857142857
GO:CC GO:0072562 blood microparticle 0.00131280680822573 140 44 4 0.0909090909090909 0.0285714285714286
GO:CC GO:0005739 mitochondrion 0.00136544086490497 1673 77 17 0.220779220779221 0.0101613867304244
GO:CC GO:0005887 integral component of plasma membrane 0.00175882275479057 1645 102 20 0.196078431372549 0.0121580547112462
GO:CC GO:0005925 focal adhesion 0.00202889452642636 420 126 10 0.0793650793650794 0.0238095238095238
GO:CC GO:0031967 organelle envelope 0.00209919601756459 1237 70 13 0.185714285714286 0.0105092966855295
GO:CC GO:0031975 envelope 0.00209919601756459 1237 70 13 0.185714285714286 0.0105092966855295
GO:CC GO:0042581 specific granule 0.00218906880715307 158 122 6 0.0491803278688525 0.0379746835443038
GO:CC GO:0030055 cell-substrate junction 0.00222746642226157 427 126 10 0.0793650793650794 0.0234192037470726
GO:CC GO:1905368 peptidase complex 0.00238068819801843 96 33 3 0.0909090909090909 0.03125
GO:CC GO:0070820 tertiary granule 0.00249300769678413 163 122 6 0.0491803278688525 0.0368098159509202
GO:CC GO:0005622 intracellular anatomical structure 0.00260287274246884 14790 136 121 0.889705882352941 0.00818120351588911
GO:CC GO:0031226 intrinsic component of plasma membrane 0.00282148173486574 1726 3 3 1 0.00173812282734647
GO:CC GO:0005741 mitochondrial outer membrane 0.00293613939292166 202 68 5 0.0735294117647059 0.0247524752475248
GO:CC GO:0016021 integral component of membrane 0.0034155056918121 5711 110 49 0.445454545454545 0.0085799334617405
GO:CC GO:0031224 intrinsic component of membrane 0.0034155056918121 5868 110 50 0.454545454545455 0.00852079072937969
GO:CC GO:0009897 external side of plasma membrane 0.00400366145306645 408 55 6 0.109090909090909 0.0147058823529412
GO:CC GO:0062023 collagen-containing extracellular matrix 0.00402062996385445 421 10 3 0.3 0.00712589073634204
GO:CC GO:0140534 endoplasmic reticulum protein-containing complex 0.00708349543633452 128 133 5 0.037593984962406 0.0390625
GO:CC GO:0070013 intracellular organelle lumen 0.00864521097186149 5402 58 27 0.46551724137931 0.00499814883376527
GO:CC GO:0031012 extracellular matrix 0.00879101382496381 562 10 3 0.3 0.00533807829181495
GO:CC GO:0030312 external encapsulating structure 0.00879101382496381 563 10 3 0.3 0.00532859680284192
GO:CC GO:0031974 membrane-enclosed lumen 0.0100316395858708 5565 76 34 0.447368421052632 0.00610961365678347
GO:CC GO:0043233 organelle lumen 0.0100316395858708 5565 76 34 0.447368421052632 0.00610961365678347
GO:CC GO:0070821 tertiary granule membrane 0.0132431050360348 72 86 3 0.0348837209302326 0.0416666666666667
GO:CC GO:0035578 azurophil granule lumen 0.0152871498999781 91 144 4 0.0277777777777778 0.043956043956044
GO:CC GO:1904724 tertiary granule lumen 0.0158615295619569 55 122 3 0.0245901639344262 0.0545454545454545
GO:CC GO:0070161 anchoring junction 0.019183449439831 836 135 13 0.0962962962962963 0.0155502392344498
GO:CC GO:0005740 mitochondrial envelope 0.0210336429880864 797 68 8 0.117647058823529 0.0100376411543287
GO:CC GO:0035579 specific granule membrane 0.0219395357313179 90 86 3 0.0348837209302326 0.0333333333333333
GO:CC GO:0030425 dendrite 0.0229664412432944 638 69 7 0.101449275362319 0.0109717868338558
GO:CC GO:0097447 dendritic tree 0.0232052650646619 640 69 7 0.101449275362319 0.0109375
GO:CC GO:0031965 nuclear membrane 0.0243168942085253 298 81 5 0.0617283950617284 0.0167785234899329
GO:CC GO:0005788 endoplasmic reticulum lumen 0.0252969590435298 307 111 6 0.0540540540540541 0.0195439739413681
GO:CC GO:0043025 neuronal cell body 0.0267209095098777 518 132 9 0.0681818181818182 0.0173745173745174
GO:CC GO:0045177 apical part of cell 0.0267209095098777 431 81 6 0.0740740740740741 0.0139211136890951
GO:CC GO:0005791 rough endoplasmic reticulum 0.028289064473205 86 102 3 0.0294117647058824 0.0348837209302326
GO:CC GO:1990904 ribonucleoprotein complex 0.0319607277251467 688 39 5 0.128205128205128 0.00726744186046512
GO:CC GO:0005856 cytoskeleton 0.0330066155195166 2332 22 7 0.318181818181818 0.00300171526586621
GO:CC GO:0036477 somatodendritic compartment 0.0330066155195166 871 69 8 0.115942028985507 0.00918484500574053
GO:CC GO:0005635 nuclear envelope 0.0357152772628411 467 81 6 0.0740740740740741 0.012847965738758
GO:CC GO:0005795 Golgi stack 0.0366614487262419 149 121 4 0.0330578512396694 0.0268456375838926
GO:CC GO:0031966 mitochondrial membrane 0.040982790352443 746 68 7 0.102941176470588 0.00938337801608579
GO:CC GO:0005938 cell cortex 0.0419631040056686 311 126 6 0.0476190476190476 0.0192926045016077
GO:CC GO:0016324 apical plasma membrane 0.0440889365856206 361 81 5 0.0617283950617284 0.0138504155124654
GO:CC GO:0044297 cell body 0.0463505951817372 592 69 6 0.0869565217391304 0.0101351351351351
GO:MF GO:0042605 peptide antigen binding 2.13477709868433e-14 30 49 9 0.183673469387755 0.3
GO:MF GO:0033218 amide binding 6.9693986336436e-09 389 32 11 0.34375 0.0282776349614396
GO:MF GO:0044183 protein folding chaperone 8.16077845722089e-09 35 69 7 0.101449275362319 0.2
GO:MF GO:0046977 TAP binding 8.8991094171755e-09 9 3 3 1 0.333333333333333
GO:MF GO:0042277 peptide binding 8.8991094171755e-09 314 32 10 0.3125 0.0318471337579618
GO:MF GO:0003823 antigen binding 2.39000150950721e-08 163 32 8 0.25 0.049079754601227
GO:MF GO:0023026 MHC class II protein complex binding 5.65758272333362e-08 17 119 6 0.0504201680672269 0.352941176470588
GO:MF GO:0044389 ubiquitin-like protein ligase binding 1.11327104135772e-07 314 69 12 0.173913043478261 0.0382165605095541
GO:MF GO:0042608 T cell receptor binding 1.48362830842063e-07 11 32 4 0.125 0.363636363636364
GO:MF GO:0023023 MHC protein complex binding 5.43641167524293e-07 25 119 6 0.0504201680672269 0.24
GO:MF GO:0031625 ubiquitin protein ligase binding 6.6916541018874e-06 296 69 10 0.144927536231884 0.0337837837837838
GO:MF GO:0032395 MHC class II receptor activity 1.21897593015882e-05 8 32 3 0.09375 0.375
GO:MF GO:0030881 beta-2-microglobulin binding 2.60815690077919e-05 7 49 3 0.0612244897959184 0.428571428571429
GO:MF GO:0019899 enzyme binding 2.66269452700376e-05 2074 132 35 0.265151515151515 0.0168756027000964
GO:MF GO:0051082 unfolded protein binding 0.00010226473242954 112 102 7 0.0686274509803922 0.0625
GO:MF GO:0031386 protein tag 0.000107008638098228 13 42 3 0.0714285714285714 0.230769230769231
GO:MF GO:0051787 misfolded protein binding 0.000114398770159348 28 20 3 0.15 0.107142857142857
GO:MF GO:0005102 signaling receptor binding 0.000199025644972306 1672 26 11 0.423076923076923 0.00657894736842105
GO:MF GO:0030234 enzyme regulator activity 0.000255609531968138 1248 143 25 0.174825174825175 0.0200320512820513
GO:MF GO:0042802 identical protein binding 0.000825674202350417 2067 143 33 0.230769230769231 0.0159651669085631
GO:MF GO:0016175 superoxide-generating NAD(P)H oxidase activity 0.00118623008666552 11 125 3 0.024 0.272727272727273
GO:MF GO:0042826 histone deacetylase binding 0.00166237141706862 116 69 5 0.072463768115942 0.0431034482758621
GO:MF GO:0140375 immune receptor activity 0.00174168255415608 133 32 4 0.125 0.0300751879699248
GO:MF GO:0098772 molecular function regulator 0.0022262218235441 2363 128 32 0.25 0.0135421074904782
GO:MF GO:0019900 kinase binding 0.00287341481609174 752 138 16 0.115942028985507 0.0212765957446809
GO:MF GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 0.00294784214696749 16 125 3 0.024 0.1875
GO:MF GO:0046983 protein dimerization activity 0.00310497781596962 1069 131 19 0.145038167938931 0.0177736202057998
GO:MF GO:0042803 protein homodimerization activity 0.00375693555227763 676 143 15 0.104895104895105 0.022189349112426
GO:MF GO:0097718 disordered domain specific binding 0.00449953601332675 34 69 3 0.0434782608695652 0.0882352941176471
GO:MF GO:0045296 cadherin binding 0.00631552355690186 333 76 7 0.0921052631578947 0.021021021021021
GO:MF GO:0005515 protein binding 0.00671236469423807 14767 139 125 0.899280575539568 0.0084648202072188
GO:MF GO:0048156 tau protein binding 0.00749758540780332 45 69 3 0.0434782608695652 0.0666666666666667
GO:MF GO:0004175 endopeptidase activity 0.00965722576709865 450 124 10 0.0806451612903226 0.0222222222222222
GO:MF GO:0031072 heat shock protein binding 0.0097742957557354 127 28 3 0.107142857142857 0.0236220472440945
GO:MF GO:0004601 peroxidase activity 0.0127254803123282 53 75 3 0.04 0.0566037735849057
GO:MF GO:0044877 protein-containing complex binding 0.0127254803123282 1287 8 4 0.5 0.00310800310800311
GO:MF GO:0001046 core promoter sequence-specific DNA binding 0.0134614872788178 43 95 3 0.0315789473684211 0.0697674418604651
GO:MF GO:0019901 protein kinase binding 0.0142561353117403 673 138 13 0.0942028985507246 0.0193164933135215
GO:MF GO:0008047 enzyme activator activity 0.014425003960738 540 30 5 0.166666666666667 0.00925925925925926
GO:MF GO:0019207 kinase regulator activity 0.014425003960738 221 143 7 0.048951048951049 0.0316742081447964
GO:MF GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 0.014425003960738 57 75 3 0.04 0.0526315789473684
GO:MF GO:0050839 cell adhesion molecule binding 0.0144782048128841 546 76 8 0.105263157894737 0.0146520146520147
GO:MF GO:0032934 sterol binding 0.0155539933724613 60 77 3 0.038961038961039 0.05
GO:MF GO:0002020 protease binding 0.017579117614267 133 37 3 0.0810810810810811 0.0225563909774436
GO:MF GO:0016504 peptidase activator activity 0.0186768109753409 42 124 3 0.0241935483870968 0.0714285714285714
GO:MF GO:0043130 ubiquitin binding 0.0192592863608287 83 132 4 0.0303030303030303 0.0481927710843374
GO:MF GO:0019887 protein kinase regulator activity 0.0219644909347698 191 143 6 0.041958041958042 0.031413612565445
GO:MF GO:0008233 peptidase activity 0.0228316648851272 646 124 11 0.0887096774193548 0.0170278637770898
GO:MF GO:0004857 enzyme inhibitor activity 0.0269206215107567 385 17 3 0.176470588235294 0.00779220779220779
GO:MF GO:0016209 antioxidant activity 0.0278248906275197 87 75 3 0.04 0.0344827586206897
GO:MF GO:0140030 modification-dependent protein binding 0.0291897822393038 160 132 5 0.0378787878787879 0.03125
GO:MF GO:0032182 ubiquitin-like protein binding 0.0291897822393038 100 132 4 0.0303030303030303 0.04
GO:MF GO:0008289 lipid binding 0.029857461934532 776 125 12 0.096 0.0154639175257732
GO:MF GO:0061135 endopeptidase regulator activity 0.0304820903147833 188 37 3 0.0810810810810811 0.0159574468085106
GO:MF GO:0001664 G protein-coupled receptor binding 0.0315725833011413 292 26 3 0.115384615384615 0.0102739726027397
GO:MF GO:0005496 steroid binding 0.0333672142739558 100 77 3 0.038961038961039 0.03
GO:MF GO:0004197 cysteine-type endopeptidase activity 0.0345792616201029 121 124 4 0.032258064516129 0.0330578512396694
GO:MF GO:0005525 GTP binding 0.0352103514727712 381 114 7 0.0614035087719298 0.0183727034120735
GO:MF GO:0032550 purine ribonucleoside binding 0.0363728051953731 386 114 7 0.0614035087719298 0.0181347150259067
GO:MF GO:0061134 peptidase regulator activity 0.0366645438791241 224 37 3 0.0810810810810811 0.0133928571428571
GO:MF GO:0001883 purine nucleoside binding 0.0366645438791241 389 114 7 0.0614035087719298 0.0179948586118252
GO:MF GO:0032549 ribonucleoside binding 0.0366645438791241 389 114 7 0.0614035087719298 0.0179948586118252
GO:MF GO:0001882 nucleoside binding 0.0391498050556336 395 114 7 0.0614035087719298 0.0177215189873418
GO:MF GO:0060589 nucleoside-triphosphatase regulator activity 0.0393434120127473 530 128 9 0.0703125 0.0169811320754717
GO:MF GO:0019001 guanyl nucleotide binding 0.0415797175769851 403 114 7 0.0614035087719298 0.0173697270471464
GO:MF GO:0032561 guanyl ribonucleotide binding 0.0415797175769851 403 114 7 0.0614035087719298 0.0173697270471464
GO:MF GO:0005518 collagen binding 0.0462071442089537 70 133 3 0.0225563909774436 0.0428571428571429
HP HP:0011450 Unusual CNS infection 0.00615678348370365 87 26 6 0.230769230769231 0.0689655172413793
HP HP:0032158 Unusual infection by anatomical site 0.00615678348370365 91 26 6 0.230769230769231 0.0659340659340659
HP HP:0002955 Granulomatosis 0.00615678348370365 10 63 4 0.0634920634920635 0.4
HP HP:0002724 Recurrent Aspergillus infections 0.0117323298351926 5 63 3 0.0476190476190476 0.6
HP HP:0001701 Pericarditis 0.0117323298351926 34 25 4 0.16 0.117647058823529
HP HP:0001287 Meningitis 0.0120364323007233 72 25 5 0.2 0.0694444444444444
HP HP:0003203 Impaired oxidative burst 0.0138165027360588 6 63 3 0.0476190476190476 0.5
HP HP:0045073 Serositis 0.0141280566220037 40 25 4 0.16 0.1
HP HP:0006510 Chronic pulmonary obstruction 0.0178309537207507 34 63 5 0.0793650793650794 0.147058823529412
HP HP:0000024 Prostatitis 0.0183260104497205 7 67 3 0.0447761194029851 0.428571428571429
HP HP:0005224 Rectal abscess 0.0221172626188446 8 63 3 0.0476190476190476 0.375
HP HP:0002113 Pulmonary infiltrates 0.0246345085825479 53 25 4 0.16 0.0754716981132075
HP HP:0011993 Impaired neutrophil bactericidal activity 0.0262751477712578 9 63 3 0.0476190476190476 0.333333333333333
HP HP:0002105 Hemoptysis 0.0308287213625018 59 25 4 0.16 0.0677966101694915
HP HP:0025021 Abnormal erythrocyte sedimentation rate 0.0334118577466255 49 33 4 0.121212121212121 0.0816326530612245
HP HP:0000763 Sensory neuropathy 0.0334118577466255 182 25 6 0.24 0.032967032967033
HP HP:0100533 Inflammatory abnormality of the eye 0.0334118577466255 193 33 7 0.212121212121212 0.0362694300518135
HP HP:0002102 Pleuritis 0.0334118577466255 25 25 3 0.12 0.12
HP HP:0003565 Elevated erythrocyte sedimentation rate 0.0334118577466255 48 33 4 0.121212121212121 0.0833333333333333
HP HP:0200042 Skin ulcer 0.0334118577466255 115 25 5 0.2 0.0434782608695652
HP HP:0001697 Abnormal pericardium morphology 0.0348691062047068 68 25 4 0.16 0.0588235294117647
HP HP:0031983 Abnormal pulmonary thoracic imaging finding 0.0396120382047326 71 25 4 0.16 0.0563380281690141
HP HP:0002840 Lymphadenitis 0.0444506184928266 13 63 3 0.0476190476190476 0.230769230769231
HP HP:0004311 Abnormal macrophage morphology 0.0470116073182307 33 25 3 0.12 0.0909090909090909
HP HP:0011990 Abnormality of neutrophil physiology 0.0490925583229196 15 63 3 0.0476190476190476 0.2
HP HP:0000246 Sinusitis 0.0490925583229196 125 131 11 0.083969465648855 0.088
HP HP:0002091 Restrictive ventilatory defect 0.0490925583229196 80 25 4 0.16 0.05
HP HP:0002103 Abnormal pleura morphology 0.0490925583229196 84 25 4 0.16 0.0476190476190476
HPA HPA:0530722 spleen; cells in white pulp[≥Medium] 3.34434421026105e-05 2645 83 43 0.518072289156627 0.0162570888468809
HPA HPA:0310443 lymph node; non-germinal center cells[High] 0.000329831209817904 1169 113 30 0.265486725663717 0.0256629597946963
HPA HPA:0530712 spleen; cells in red pulp[≥Medium] 0.000329831209817904 3049 127 61 0.480314960629921 0.020006559527714
HPA HPA:0600443 tonsil; non-germinal center cells[High] 0.000506964108744109 1271 82 25 0.304878048780488 0.019669551534225
HPA HPA:0310442 lymph node; non-germinal center cells[≥Medium] 0.000740713889643721 3875 86 51 0.593023255813954 0.0131612903225806
HPA HPA:0530721 spleen; cells in white pulp[≥Low] 0.00183781180939497 4249 92 56 0.608695652173913 0.0131795716639209
HPA HPA:0091003 cerebellum; molecular layer cells - cytoplasm/membrane[High] 0.00212882222440261 182 121 10 0.0826446280991736 0.0549450549450549
HPA HPA:0300413 lung; macrophages[High] 0.00212882222440261 1224 112 28 0.25 0.0228758169934641
HPA HPA:0600442 tonsil; non-germinal center cells[≥Medium] 0.00404612763434744 4079 137 74 0.54014598540146 0.0181417013974013
HPA HPA:0091033 cerebellum; processes in molecular layer[High] 0.00801955053613179 108 121 7 0.0578512396694215 0.0648148148148148
HPA HPA:0530711 spleen; cells in red pulp[≥Low] 0.00801955053613179 5195 133 85 0.639097744360902 0.0163618864292589
HPA HPA:0530713 spleen; cells in red pulp[High] 0.0338876523861478 778 102 17 0.166666666666667 0.0218508997429306
HPA HPA:0310433 lymph node; germinal center cells[High] 0.0339902165184661 908 81 16 0.197530864197531 0.0176211453744493
HPA HPA:0310441 lymph node; non-germinal center cells[≥Low] 0.0346868426319418 5915 87 62 0.71264367816092 0.0104818258664413
HPA HPA:0460643 skin 1; Langerhans[High] 0.0346868426319418 734 58 11 0.189655172413793 0.0149863760217984
HPA HPA:0600441 tonsil; non-germinal center cells[≥Low] 0.0346868426319418 5966 90 64 0.711111111111111 0.0107274555816292
HPA HPA:0090972 cerebellum; granular cells - cytoplasm/membrane[≥Medium] 0.0346868426319418 231 121 9 0.0743801652892562 0.038961038961039
HPA HPA:0091032 cerebellum; processes in molecular layer[≥Medium] 0.0346868426319418 192 121 8 0.0661157024793388 0.0416666666666667
HPA HPA:0040082 bone marrow; hematopoietic cells[≥Medium] 0.0346868426319418 4126 92 50 0.543478260869565 0.0121182743577315
HPA HPA:0310432 lymph node; germinal center cells[≥Medium] 0.0346868426319418 3209 83 38 0.457831325301205 0.0118416952321596
HPA HPA:0090971 cerebellum; granular cells - cytoplasm/membrane[≥Low] 0.0377807033015462 297 121 10 0.0826446280991736 0.0336700336700337
HPA HPA:0091002 cerebellum; molecular layer cells - cytoplasm/membrane[≥Medium] 0.040173572410698 309 100 9 0.09 0.029126213592233
HPA HPA:0091031 cerebellum; processes in molecular layer[≥Low] 0.040173572410698 204 121 8 0.0661157024793388 0.0392156862745098
HPA HPA:0090973 cerebellum; granular cells - cytoplasm/membrane[High] 0.040173572410698 132 109 6 0.055045871559633 0.0454545454545455
KEGG KEGG:04612 Antigen processing and presentation 7.23641171139899e-19 69 69 17 0.246376811594203 0.246376811594203
KEGG KEGG:05330 Allograft rejection 2.28466552370155e-11 34 49 9 0.183673469387755 0.264705882352941
KEGG KEGG:05332 Graft-versus-host disease 3.56382224210409e-11 37 49 9 0.183673469387755 0.243243243243243
KEGG KEGG:05416 Viral myocarditis 5.36699586748101e-11 56 52 10 0.192307692307692 0.178571428571429
KEGG KEGG:04940 Type I diabetes mellitus 5.36699586748101e-11 40 49 9 0.183673469387755 0.225
KEGG KEGG:05320 Autoimmune thyroid disease 2.78719977995233e-10 49 49 9 0.183673469387755 0.183673469387755
KEGG KEGG:04145 Phagosome 5.04800651807658e-10 147 131 18 0.137404580152672 0.122448979591837
KEGG KEGG:05169 Epstein-Barr virus infection 6.0327430972494e-08 198 32 10 0.3125 0.0505050505050505
KEGG KEGG:05145 Toxoplasmosis 1.42763031752144e-07 109 32 8 0.25 0.073394495412844
KEGG KEGG:04650 Natural killer cell mediated cytotoxicity 9.31147010282479e-07 123 4 4 1 0.032520325203252
KEGG KEGG:04514 Cell adhesion molecules 1.17216384528645e-06 146 32 8 0.25 0.0547945205479452
KEGG KEGG:04218 Cellular senescence 1.92079639406901e-06 156 4 4 1 0.0256410256410256
KEGG KEGG:05140 Leishmaniasis 1.92079639406901e-06 72 125 10 0.08 0.138888888888889
KEGG KEGG:05170 Human immunodeficiency virus 1 infection 2.98857296087628e-06 210 7 5 0.714285714285714 0.0238095238095238
KEGG KEGG:05167 Kaposi sarcoma-associated herpesvirus infection 3.83125396709015e-06 193 4 4 1 0.0207253886010363
KEGG KEGG:05203 Viral carcinogenesis 4.31615677385289e-06 202 4 4 1 0.0198019801980198
KEGG KEGG:05166 Human T-cell leukemia virus 1 infection 5.3213688272166e-06 216 4 4 1 0.0185185185185185
KEGG KEGG:05163 Human cytomegalovirus infection 5.71461506302127e-06 223 4 4 1 0.0179372197309417
KEGG KEGG:04144 Endocytosis 8.85618564600069e-06 252 4 4 1 0.0158730158730159
KEGG KEGG:05168 Herpes simplex virus 1 infection 1.18465014212136e-05 494 8 6 0.75 0.0121457489878543
KEGG KEGG:05165 Human papillomavirus infection 2.39871734375966e-05 331 4 4 1 0.0120845921450151
KEGG KEGG:05310 Asthma 2.74234746539503e-05 27 32 4 0.125 0.148148148148148
KEGG KEGG:04142 Lysosome 2.74234746539503e-05 128 99 10 0.101010101010101 0.078125
KEGG KEGG:05321 Inflammatory bowel disease 2.96485579530624e-05 62 32 5 0.15625 0.0806451612903226
KEGG KEGG:05152 Tuberculosis 3.15341685979772e-05 175 32 7 0.21875 0.04
KEGG KEGG:05164 Influenza A 6.63702254482286e-05 169 51 8 0.156862745098039 0.0473372781065089
KEGG KEGG:05323 Rheumatoid arthritis 0.000151048094631094 88 109 8 0.073394495412844 0.0909090909090909
KEGG KEGG:04658 Th1 and Th2 cell differentiation 0.000151048094631094 89 32 5 0.15625 0.0561797752808989
KEGG KEGG:04659 Th17 cell differentiation 0.000166288042923661 104 69 7 0.101449275362319 0.0673076923076923
KEGG KEGG:04672 Intestinal immune network for IgA production 0.000166288042923661 45 32 4 0.125 0.0888888888888889
KEGG KEGG:04380 Osteoclast differentiation 0.000781222564218075 125 125 9 0.072 0.072
KEGG KEGG:05150 Staphylococcus aureus infection 0.00203296057356477 87 32 4 0.125 0.0459770114942529
KEGG KEGG:04640 Hematopoietic cell lineage 0.00275702574134222 95 32 4 0.125 0.0421052631578947
KEGG KEGG:05418 Fluid shear stress and atherosclerosis 0.00597401734411128 138 69 6 0.0869565217391304 0.0434782608695652
KEGG KEGG:05322 Systemic lupus erythematosus 0.00889537282681701 132 32 4 0.125 0.0303030303030303
KEGG KEGG:04217 Necroptosis 0.0180043321775718 159 127 8 0.062992125984252 0.050314465408805
KEGG KEGG:04621 NOD-like receptor signaling pathway 0.0192698694247139 177 69 6 0.0869565217391304 0.0338983050847458
KEGG KEGG:04915 Estrogen signaling pathway 0.0208303152387169 137 20 3 0.15 0.0218978102189781
KEGG KEGG:04141 Protein processing in endoplasmic reticulum 0.0312408604609671 170 132 8 0.0606060606060606 0.0470588235294118
KEGG KEGG:05162 Measles 0.0425082815566016 139 26 3 0.115384615384615 0.0215827338129496
KEGG KEGG:04120 Ubiquitin mediated proteolysis 0.0440737566812382 139 50 4 0.08 0.0287769784172662
KEGG KEGG:03050 Proteasome 0.0471609737087318 46 83 3 0.036144578313253 0.0652173913043478
MIRNA MIRNA:hsa-miR-4656 hsa-miR-4656 0.0160917839768956 71 11 3 0.272727272727273 0.0422535211267606
MIRNA MIRNA:hsa-miR-146a-5p hsa-miR-146a-5p 0.0160917839768956 200 141 10 0.0709219858156028 0.05
MIRNA MIRNA:hsa-miR-324-3p hsa-miR-324-3p 0.0232844319174673 336 87 9 0.103448275862069 0.0267857142857143
MIRNA MIRNA:hsa-miR-339-5p hsa-miR-339-5p 0.030881058165128 235 20 4 0.2 0.0170212765957447
MIRNA MIRNA:hsa-miR-6798-5p hsa-miR-6798-5p 0.0351081141161364 120 118 6 0.0508474576271186 0.05
MIRNA MIRNA:hsa-miR-330-5p hsa-miR-330-5p 0.0436558968392037 121 20 3 0.15 0.0247933884297521
MIRNA MIRNA:hsa-miR-3674 hsa-miR-3674 0.0486998643884799 107 56 4 0.0714285714285714 0.0373831775700935
MIRNA MIRNA:hsa-miR-221-3p hsa-miR-221-3p 0.0486998643884799 366 44 6 0.136363636363636 0.0163934426229508
MIRNA MIRNA:hsa-miR-326 hsa-miR-326 0.0494823781219897 136 20 3 0.15 0.0220588235294118
MIRNA MIRNA:hsa-miR-6876-3p hsa-miR-6876-3p 0.0494823781219897 39 69 3 0.0434782608695652 0.0769230769230769
REAC REAC:R-HSA-913531 Interferon Signaling 1.86824370444693e-19 191 51 20 0.392156862745098 0.104712041884817
REAC REAC:R-HSA-909733 Interferon alpha/beta signaling 6.15674053602782e-14 66 51 12 0.235294117647059 0.181818181818182
REAC REAC:R-HSA-168249 Innate Immune System 2.81436717007505e-12 1073 86 36 0.418604651162791 0.0335507921714818
REAC REAC:R-HSA-168256 Immune System 2.81436717007505e-12 2139 78 47 0.602564102564103 0.0219728845254792
REAC REAC:R-HSA-1236975 Antigen processing-Cross presentation 3.70860610823384e-12 99 83 14 0.168674698795181 0.141414141414141
REAC REAC:R-HSA-1236977 Endosomal/Vacuolar pathway 7.93173496205851e-11 11 4 4 1 0.363636363636364
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 1.02318803372785e-10 842 51 23 0.450980392156863 0.0273159144893112
REAC REAC:R-HSA-877300 Interferon gamma signaling 2.58845803687866e-10 87 32 9 0.28125 0.103448275862069
REAC REAC:R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 2.02699893474828e-09 25 4 4 1 0.16
REAC REAC:R-HSA-1236974 ER-Phagosome pathway 2.68974143747783e-09 83 83 11 0.132530120481928 0.132530120481928
REAC REAC:R-HSA-1280218 Adaptive Immune System 2.68974143747783e-09 800 67 24 0.358208955223881 0.03
REAC REAC:R-HSA-6798695 Neutrophil degranulation 2.46267456654055e-08 474 100 22 0.22 0.0464135021097046
REAC REAC:R-HSA-202403 TCR signaling 8.49153119687588e-08 120 45 9 0.2 0.075
REAC REAC:R-HSA-202424 Downstream TCR signaling 2.01190138802343e-07 98 42 8 0.19047619047619 0.0816326530612245
REAC REAC:R-HSA-983169 Class I MHC mediated antigen processing & presentation 2.41107988832867e-07 370 131 21 0.16030534351145 0.0567567567567568
REAC REAC:R-HSA-3371568 Attenuation phase 9.19183205541438e-07 14 69 5 0.072463768115942 0.357142857142857
REAC REAC:R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 2.6967496675693e-06 54 42 6 0.142857142857143 0.111111111111111
REAC REAC:R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 3.46534015336066e-06 181 4 4 1 0.0220994475138122
REAC REAC:R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 1.2338191796404e-05 20 32 4 0.125 0.2
REAC REAC:R-HSA-202433 Generation of second messenger molecules 1.2338191796404e-05 35 45 5 0.111111111111111 0.142857142857143
REAC REAC:R-HSA-3371571 HSF1-dependent transactivation 1.41335847904699e-05 24 69 5 0.072463768115942 0.208333333333333
REAC REAC:R-HSA-2132295 MHC class II antigen presentation 1.83809300675072e-05 123 62 8 0.129032258064516 0.0650406504065041
REAC REAC:R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 1.91747886142361e-05 23 32 4 0.125 0.173913043478261
REAC REAC:R-HSA-389948 PD-1 signaling 2.20041480013283e-05 24 32 4 0.125 0.166666666666667
REAC REAC:R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 3.03881048884731e-05 86 42 6 0.142857142857143 0.0697674418604651
REAC REAC:R-HSA-5687128 MAPK6/MAPK4 signaling 3.57979403781721e-05 89 42 6 0.142857142857143 0.0674157303370786
REAC REAC:R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 7.3147579484054e-05 79 83 7 0.0843373493975904 0.0886075949367089
REAC REAC:R-HSA-1222556 ROS and RNS production in phagocytes 9.49903269676221e-05 36 125 6 0.048 0.166666666666667
REAC REAC:R-HSA-446652 Interleukin-1 family signaling 0.000155020870378191 138 127 10 0.078740157480315 0.072463768115942
REAC REAC:R-HSA-5336415 Uptake and function of diphtheria toxin 0.000175334177587358 6 76 3 0.0394736842105263 0.5
REAC REAC:R-HSA-8939902 Regulation of RUNX2 expression and activity 0.000201466958271399 71 42 5 0.119047619047619 0.0704225352112676
REAC REAC:R-HSA-388841 Costimulation by the CD28 family 0.000207302675719254 67 45 5 0.111111111111111 0.0746268656716418
REAC REAC:R-HSA-9613829 Chaperone Mediated Autophagy 0.000252841000281231 22 69 4 0.0579710144927536 0.181818181818182
REAC REAC:R-HSA-5656169 Termination of translesion DNA synthesis 0.000318525472555134 32 50 4 0.08 0.125
REAC REAC:R-HSA-1169408 ISG15 antiviral mechanism 0.000386624135849597 70 50 5 0.1 0.0714285714285714
REAC REAC:R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 0.000386624135849597 34 50 4 0.08 0.117647058823529
REAC REAC:R-HSA-2262752 Cellular responses to stress 0.000395213839931883 546 83 15 0.180722891566265 0.0274725274725275
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 0.000517806649545966 560 83 15 0.180722891566265 0.0267857142857143
REAC REAC:R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 0.000603430193160066 57 69 5 0.072463768115942 0.087719298245614
REAC REAC:R-HSA-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 0.000603430193160066 39 50 4 0.08 0.102564102564103
REAC REAC:R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 0.000603430193160066 78 50 5 0.1 0.0641025641025641
REAC REAC:R-HSA-5675482 Regulation of necroptotic cell death 0.000729589481906564 17 43 3 0.0697674418604651 0.176470588235294
REAC REAC:R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 0.000741396417029966 50 83 5 0.0602409638554217 0.1
REAC REAC:R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 0.000776475013065108 52 42 4 0.0952380952380952 0.0769230769230769
REAC REAC:R-HSA-69610 p53-Independent DNA Damage Response 0.000776475013065108 52 42 4 0.0952380952380952 0.0769230769230769
REAC REAC:R-HSA-180534 Vpu mediated degradation of CD4 0.000776475013065108 52 42 4 0.0952380952380952 0.0769230769230769
REAC REAC:R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 0.000776475013065108 52 42 4 0.0952380952380952 0.0769230769230769
REAC REAC:R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 0.000776475013065108 52 42 4 0.0952380952380952 0.0769230769230769
REAC REAC:R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 0.000776475013065108 52 42 4 0.0952380952380952 0.0769230769230769
REAC REAC:R-HSA-9604323 Negative regulation of NOTCH4 signaling 0.000789129229983252 53 42 4 0.0952380952380952 0.0754716981132075
REAC REAC:R-HSA-180585 Vif-mediated degradation of APOBEC3G 0.000789129229983252 53 42 4 0.0952380952380952 0.0754716981132075
REAC REAC:R-HSA-169911 Regulation of Apoptosis 0.000789129229983252 53 42 4 0.0952380952380952 0.0754716981132075
REAC REAC:R-HSA-5218859 Regulated Necrosis 0.000803453447394238 19 43 3 0.0697674418604651 0.157894736842105
REAC REAC:R-HSA-5213460 RIPK1-mediated regulated necrosis 0.000803453447394238 19 43 3 0.0697674418604651 0.157894736842105
REAC REAC:R-HSA-8941858 Regulation of RUNX3 expression and activity 0.000803453447394238 54 42 4 0.0952380952380952 0.0740740740740741
REAC REAC:R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 0.000819287192082524 55 42 4 0.0952380952380952 0.0727272727272727
REAC REAC:R-HSA-4641257 Degradation of AXIN 0.000819287192082524 55 42 4 0.0952380952380952 0.0727272727272727
REAC REAC:R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 0.000819287192082524 55 42 4 0.0952380952380952 0.0727272727272727
REAC REAC:R-HSA-5362768 Hh mutants are degraded by ERAD 0.000864858638951732 56 42 4 0.0952380952380952 0.0714285714285714
REAC REAC:R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 0.00089127245741741 17 56 3 0.0535714285714286 0.176470588235294
REAC REAC:R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 0.00089127245741741 59 42 4 0.0952380952380952 0.0677966101694915
REAC REAC:R-HSA-4086400 PCP/CE pathway 0.00089127245741741 92 83 6 0.072289156626506 0.0652173913043478
REAC REAC:R-HSA-5676590 NIK-->noncanonical NF-kB signaling 0.00089127245741741 59 42 4 0.0952380952380952 0.0677966101694915
REAC REAC:R-HSA-2424491 DAP12 signaling 0.00089127245741741 25 100 4 0.04 0.16
REAC REAC:R-HSA-1236973 Cross-presentation of particulate exogenous antigens (phagosomes) 0.00089127245741741 8 125 3 0.024 0.375
REAC REAC:R-HSA-5387390 Hh mutants abrogate ligand secretion 0.00089127245741741 59 42 4 0.0952380952380952 0.0677966101694915
REAC REAC:R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 0.00089127245741741 17 56 3 0.0535714285714286 0.176470588235294
REAC REAC:R-HSA-73893 DNA Damage Bypass 0.00089127245741741 48 50 4 0.08 0.0833333333333333
REAC REAC:R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 0.00089127245741741 60 42 4 0.0952380952380952 0.0666666666666667
REAC REAC:R-HSA-4641258 Degradation of DVL 0.00089127245741741 57 42 4 0.0952380952380952 0.0701754385964912
REAC REAC:R-HSA-5610780 Degradation of GLI1 by the proteasome 0.00089127245741741 60 42 4 0.0952380952380952 0.0666666666666667
REAC REAC:R-HSA-5610783 Degradation of GLI2 by the proteasome 0.00089127245741741 60 42 4 0.0952380952380952 0.0666666666666667
REAC REAC:R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 0.00089127245741741 60 42 4 0.0952380952380952 0.0666666666666667
REAC REAC:R-HSA-69541 Stabilization of p53 0.00089127245741741 57 42 4 0.0952380952380952 0.0701754385964912
REAC REAC:R-HSA-1433557 Signaling by SCF-KIT 0.00089127245741741 38 127 5 0.0393700787401575 0.131578947368421
REAC REAC:R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 0.00089127245741741 60 42 4 0.0952380952380952 0.0666666666666667
REAC REAC:R-HSA-5678895 Defective CFTR causes cystic fibrosis 0.000916190239335059 61 42 4 0.0952380952380952 0.0655737704918033
REAC REAC:R-HSA-8878166 Transcriptional regulation by RUNX2 0.000925759409525603 118 42 5 0.119047619047619 0.0423728813559322
REAC REAC:R-HSA-9678108 SARS-CoV-1 Infection 0.00103927211904314 50 102 5 0.0490196078431373 0.1
REAC REAC:R-HSA-4608870 Asymmetric localization of PCP proteins 0.00103927211904314 64 42 4 0.0952380952380952 0.0625
REAC REAC:R-HSA-9664873 Pexophagy 0.00103927211904314 11 96 3 0.03125 0.272727272727273
REAC REAC:R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 0.00103927211904314 64 42 4 0.0952380952380952 0.0625
REAC REAC:R-HSA-5358346 Hedgehog ligand biogenesis 0.0010910896633255 65 42 4 0.0952380952380952 0.0615384615384615
REAC REAC:R-HSA-69563 p53-Dependent G1 DNA Damage Response 0.00111820548607505 66 42 4 0.0952380952380952 0.0606060606060606
REAC REAC:R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 0.00111820548607505 66 42 4 0.0952380952380952 0.0606060606060606
REAC REAC:R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 0.00111820548607505 66 42 4 0.0952380952380952 0.0606060606060606
REAC REAC:R-HSA-1169091 Activation of NF-kappaB in B cells 0.00115913515202418 67 42 4 0.0952380952380952 0.0597014925373134
REAC REAC:R-HSA-5658442 Regulation of RAS by GAPs 0.00115913515202418 67 42 4 0.0952380952380952 0.0597014925373134
REAC REAC:R-HSA-9683701 Translation of structural proteins 0.00116605410380031 28 102 4 0.0392156862745098 0.142857142857143
REAC REAC:R-HSA-69615 G1/S DNA Damage Checkpoints 0.00117521978142603 68 42 4 0.0952380952380952 0.0588235294117647
REAC REAC:R-HSA-68867 Assembly of the pre-replicative complex 0.00117521978142603 68 42 4 0.0952380952380952 0.0588235294117647
REAC REAC:R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 0.00117521978142603 68 42 4 0.0952380952380952 0.0588235294117647
REAC REAC:R-HSA-982772 Growth hormone receptor signaling 0.00117538278010717 23 127 4 0.031496062992126 0.173913043478261
REAC REAC:R-HSA-8948751 Regulation of PTEN stability and activity 0.00121776433642444 69 42 4 0.0952380952380952 0.0579710144927536
REAC REAC:R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 0.00128700678909503 24 125 4 0.032 0.166666666666667
REAC REAC:R-HSA-68949 Orc1 removal from chromatin 0.00133275744842324 71 42 4 0.0952380952380952 0.0563380281690141
REAC REAC:R-HSA-209543 p75NTR recruits signalling complexes 0.0014388478517455 13 96 3 0.03125 0.230769230769231
REAC REAC:R-HSA-209560 NF-kB is activated and signals survival 0.0014388478517455 13 96 3 0.03125 0.230769230769231
REAC REAC:R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 0.0014388478517455 73 42 4 0.0952380952380952 0.0547945205479452
REAC REAC:R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 0.0014388478517455 73 42 4 0.0952380952380952 0.0547945205479452
REAC REAC:R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 0.00147354920280875 74 42 4 0.0952380952380952 0.0540540540540541
REAC REAC:R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 0.00147354920280875 74 42 4 0.0952380952380952 0.0540540540540541
REAC REAC:R-HSA-1234174 Cellular response to hypoxia 0.00153716643511141 75 42 4 0.0952380952380952 0.0533333333333333
REAC REAC:R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 0.00159896133309042 485 127 16 0.125984251968504 0.0329896907216495
REAC REAC:R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 0.00159896133309042 76 42 4 0.0952380952380952 0.0526315789473684
REAC REAC:R-HSA-1643713 Signaling by EGFR in Cancer 0.00161677807389554 23 56 3 0.0535714285714286 0.130434782608696
REAC REAC:R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 0.00162358781665483 77 42 4 0.0952380952380952 0.051948051948052
REAC REAC:R-HSA-5619084 ABC transporter disorders 0.00162358781665483 77 42 4 0.0952380952380952 0.051948051948052
REAC REAC:R-HSA-3371556 Cellular response to heat stress 0.00169040904865826 87 69 5 0.072463768115942 0.0574712643678161
REAC REAC:R-HSA-2172127 DAP12 interactions 0.00169040904865826 33 100 4 0.04 0.121212121212121
REAC REAC:R-HSA-9020956 Interleukin-27 signaling 0.00173879865264741 11 127 3 0.0236220472440945 0.272727272727273
REAC REAC:R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 0.00181458804717092 80 42 4 0.0952380952380952 0.05
REAC REAC:R-HSA-9013694 Signaling by NOTCH4 0.001870263374117 81 42 4 0.0952380952380952 0.0493827160493827
REAC REAC:R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 0.001870263374117 81 42 4 0.0952380952380952 0.0493827160493827
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.00188987810569343 446 127 15 0.118110236220472 0.0336322869955157
REAC REAC:R-HSA-9020702 Interleukin-1 signaling 0.00195139513366877 101 96 6 0.0625 0.0594059405940594
REAC REAC:R-HSA-69202 Cyclin E associated events during G1/S transition 0.00198483194434991 83 42 4 0.0952380952380952 0.0481927710843374
REAC REAC:R-HSA-195253 Degradation of beta-catenin by the destruction complex 0.00198483194434991 83 42 4 0.0952380952380952 0.0481927710843374
REAC REAC:R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 0.00208675911332445 85 42 4 0.0952380952380952 0.0470588235294118
REAC REAC:R-HSA-8984722 Interleukin-35 Signalling 0.00208675911332445 12 127 3 0.0236220472440945 0.25
REAC REAC:R-HSA-69002 DNA Replication Pre-Initiation 0.00208675911332445 85 42 4 0.0952380952380952 0.0470588235294118
REAC REAC:R-HSA-5632684 Hedgehog 'on' state 0.00208675911332445 85 42 4 0.0952380952380952 0.0470588235294118
REAC REAC:R-HSA-205043 NRIF signals cell death from the nucleus 0.0022139743129885 16 96 3 0.03125 0.1875
REAC REAC:R-HSA-193639 p75NTR signals via NF-kB 0.0022139743129885 16 96 3 0.03125 0.1875
REAC REAC:R-HSA-8863795 Downregulation of ERBB2 signaling 0.00221615068301748 27 56 3 0.0535714285714286 0.111111111111111
REAC REAC:R-HSA-168898 Toll-like Receptor Cascades 0.00227263880811712 152 67 6 0.0895522388059701 0.0394736842105263
REAC REAC:R-HSA-453276 Regulation of mitotic cell cycle 0.00227263880811712 88 42 4 0.0952380952380952 0.0454545454545455
REAC REAC:R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 0.00227263880811712 88 42 4 0.0952380952380952 0.0454545454545455
REAC REAC:R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 0.00251097300214959 76 50 4 0.08 0.0526315789473684
REAC REAC:R-HSA-69052 Switching of origins to a post-replicative state 0.00252412354268889 91 42 4 0.0952380952380952 0.043956043956044
REAC REAC:R-HSA-5689603 UCH proteinases 0.00261163893120796 92 42 4 0.0952380952380952 0.0434782608695652
REAC REAC:R-HSA-109581 Apoptosis 0.00271684810431599 174 85 7 0.0823529411764706 0.0402298850574713
REAC REAC:R-HSA-8878159 Transcriptional regulation by RUNX3 0.00277189581470145 94 42 4 0.0952380952380952 0.0425531914893617
REAC REAC:R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 0.00277189581470145 94 42 4 0.0952380952380952 0.0425531914893617
REAC REAC:R-HSA-5357801 Programmed Cell Death 0.00284329218789588 177 85 7 0.0823529411764706 0.0395480225988701
REAC REAC:R-HSA-9010553 Regulation of expression of SLITs and ROBOs 0.0028447254232227 171 42 5 0.119047619047619 0.0292397660818713
REAC REAC:R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 0.0028447254232227 182 83 7 0.0843373493975904 0.0384615384615385
REAC REAC:R-HSA-69275 G2/M Transition 0.0028447254232227 196 126 9 0.0714285714285714 0.0459183673469388
REAC REAC:R-HSA-5607764 CLEC7A (Dectin-1) signaling 0.00290995923382567 97 42 4 0.0952380952380952 0.0412371134020619
REAC REAC:R-HSA-453274 Mitotic G2-G2/M phases 0.00301313257095154 198 126 9 0.0714285714285714 0.0454545454545455
REAC REAC:R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 0.00319966502207645 100 42 4 0.0952380952380952 0.04
REAC REAC:R-HSA-3858494 Beta-catenin independent WNT signaling 0.00327419634842124 143 52 5 0.0961538461538462 0.034965034965035
REAC REAC:R-HSA-3371453 Regulation of HSF1-mediated heat shock response 0.00347856175613459 67 28 3 0.107142857142857 0.0447761194029851
REAC REAC:R-HSA-382556 ABC-family proteins mediated transport 0.00348380923313266 103 42 4 0.0952380952380952 0.0388349514563107
REAC REAC:R-HSA-5339562 Uptake and actions of bacterial toxins 0.00353607944473611 25 76 3 0.0394736842105263 0.12
REAC REAC:R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 0.00378964237526058 110 70 5 0.0714285714285714 0.0454545454545455
REAC REAC:R-HSA-9012852 Signaling by NOTCH3 0.00418890093292802 48 42 3 0.0714285714285714 0.0625
REAC REAC:R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 0.00421962805915407 35 132 4 0.0303030303030303 0.114285714285714
REAC REAC:R-HSA-5205685 PINK1-PRKN Mediated Mitophagy 0.00451088157688403 22 96 3 0.03125 0.136363636363636
REAC REAC:R-HSA-5610787 Hedgehog 'off' state 0.00460108935871834 113 42 4 0.0952380952380952 0.0353982300884956
REAC REAC:R-HSA-157118 Signaling by NOTCH 0.00469460825493593 197 42 5 0.119047619047619 0.0253807106598985
REAC REAC:R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 0.00524688466389307 53 42 3 0.0714285714285714 0.0566037735849057
REAC REAC:R-HSA-162588 Budding and maturation of HIV virion 0.00524688466389307 28 80 3 0.0375 0.107142857142857
REAC REAC:R-HSA-5683057 MAPK family signaling cascades 0.00551978897365344 308 42 6 0.142857142857143 0.0194805194805195
REAC REAC:R-HSA-69239 Synthesis of DNA 0.00551978897365344 120 42 4 0.0952380952380952 0.0333333333333333
REAC REAC:R-HSA-9679506 SARS-CoV Infections 0.00563813926502346 85 102 5 0.0490196078431373 0.0588235294117647
REAC REAC:R-HSA-162909 Host Interactions of HIV factors 0.00609928494882887 125 42 4 0.0952380952380952 0.032
REAC REAC:R-HSA-9646399 Aggrephagy 0.00624246980834548 44 56 3 0.0535714285714286 0.0681818181818182
REAC REAC:R-HSA-376176 Signaling by ROBO receptors 0.00624246980834548 217 42 5 0.119047619047619 0.0230414746543779
REAC REAC:R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 0.00624246980834548 31 80 3 0.0375 0.0967741935483871
REAC REAC:R-HSA-69306 DNA Replication 0.00624246980834548 128 42 4 0.0952380952380952 0.03125
REAC REAC:R-HSA-69206 G1/S Transition 0.00669116517757539 131 42 4 0.0952380952380952 0.0305343511450382
REAC REAC:R-HSA-1227986 Signaling by ERBB2 0.00673296153508813 46 56 3 0.0535714285714286 0.0652173913043478
REAC REAC:R-HSA-5205647 Mitophagy 0.00673296153508813 27 96 3 0.03125 0.111111111111111
REAC REAC:R-HSA-983705 Signaling by the B Cell Receptor (BCR) 0.00673296153508813 164 83 6 0.072289156626506 0.0365853658536585
REAC REAC:R-HSA-901042 Calnexin/calreticulin cycle 0.00707291412725374 26 102 3 0.0294117647058824 0.115384615384615
REAC REAC:R-HSA-9008059 Interleukin-37 signaling 0.00707291412725374 21 127 3 0.0236220472440945 0.142857142857143
REAC REAC:R-HSA-2871837 FCERI mediated NF-kB activation 0.00723690549462262 136 42 4 0.0952380952380952 0.0294117647058824
REAC REAC:R-HSA-5621481 C-type lectin receptors (CLRs) 0.00723690549462262 136 42 4 0.0952380952380952 0.0294117647058824
REAC REAC:R-HSA-9615710 Late endosomal microautophagy 0.00750897015213187 34 80 3 0.0375 0.0882352941176471
REAC REAC:R-HSA-6807070 PTEN Regulation 0.00752216431195285 138 42 4 0.0952380952380952 0.0289855072463768
REAC REAC:R-HSA-9612973 Autophagy 0.00822687245378674 149 96 6 0.0625 0.0402684563758389
REAC REAC:R-HSA-4420097 VEGFA-VEGFR2 Pathway 0.00822842269261917 94 63 4 0.0634920634920635 0.0425531914893617
REAC REAC:R-HSA-453279 Mitotic G1 phase and G1/S transition 0.00930188087515623 148 42 4 0.0952380952380952 0.027027027027027
REAC REAC:R-HSA-917937 Iron uptake and transport 0.00931930796197812 57 109 4 0.036697247706422 0.0701754385964912
REAC REAC:R-HSA-977225 Amyloid fiber formation 0.00931930796197812 73 85 4 0.0470588235294118 0.0547945205479452
REAC REAC:R-HSA-69481 G2/M Checkpoints 0.00931930796197812 149 42 4 0.0952380952380952 0.0268456375838926
REAC REAC:R-HSA-5358351 Signaling by Hedgehog 0.00931930796197812 149 42 4 0.0952380952380952 0.0268456375838926
REAC REAC:R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 0.00962749059902149 94 67 4 0.0597014925373134 0.0425531914893617
REAC REAC:R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 0.00962749059902149 94 67 4 0.0597014925373134 0.0425531914893617
REAC REAC:R-HSA-8852135 Protein ubiquitination 0.00976120369344237 73 42 3 0.0714285714285714 0.0410958904109589
REAC REAC:R-HSA-373755 Semaphorin interactions 0.00997390614563975 64 100 4 0.04 0.0625
REAC REAC:R-HSA-5663205 Infectious disease 0.0100696049793679 815 89 15 0.168539325842697 0.0184049079754601
REAC REAC:R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 0.0100696049793679 308 50 6 0.12 0.0194805194805195
REAC REAC:R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 0.0103333050042669 97 67 4 0.0597014925373134 0.0412371134020619
REAC REAC:R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 0.0103333050042669 97 67 4 0.0597014925373134 0.0412371134020619
REAC REAC:R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers 0.0103333050042669 371 56 7 0.125 0.0188679245283019
REAC REAC:R-HSA-194138 Signaling by VEGF 0.0104264370602228 104 63 4 0.0634920634920635 0.0384615384615385
REAC REAC:R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 0.0104768679195677 85 126 5 0.0396825396825397 0.0588235294117647
REAC REAC:R-HSA-69242 S Phase 0.0113287171784214 162 42 4 0.0952380952380952 0.0246913580246914
REAC REAC:R-HSA-8953854 Metabolism of RNA 0.011561317798907 658 42 8 0.19047619047619 0.0121580547112462
REAC REAC:R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 0.011561317798907 55 124 4 0.032258064516129 0.0727272727272727
REAC REAC:R-HSA-5619115 Disorders of transmembrane transporters 0.0137074463268188 173 42 4 0.0952380952380952 0.023121387283237
REAC REAC:R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE 0.0141140036903303 76 96 4 0.0416666666666667 0.0526315789473684
REAC REAC:R-HSA-9663891 Selective autophagy 0.0163496422839986 80 96 4 0.0416666666666667 0.05
REAC REAC:R-HSA-2467813 Separation of Sister Chromatids 0.0168770543988135 188 42 4 0.0952380952380952 0.0212765957446809
REAC REAC:R-HSA-2142753 Arachidonic acid metabolism 0.0180631118536376 59 70 3 0.0428571428571429 0.0508474576271186
REAC REAC:R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 0.0181036229568927 50 83 3 0.036144578313253 0.06
REAC REAC:R-HSA-1632852 Macroautophagy 0.0186484300810588 134 96 5 0.0520833333333333 0.0373134328358209
REAC REAC:R-HSA-1257604 PIP3 activates AKT signaling 0.0186484300810588 249 52 5 0.0961538461538462 0.0200803212851406
REAC REAC:R-HSA-201681 TCF dependent signaling in response to WNT 0.0186484300810588 196 42 4 0.0952380952380952 0.0204081632653061
REAC REAC:R-HSA-114604 GPVI-mediated activation cascade 0.0186484300810588 35 122 3 0.0245901639344262 0.0857142857142857
REAC REAC:R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 0.0186484300810588 51 83 3 0.036144578313253 0.0588235294117647
REAC REAC:R-HSA-5689880 Ub-specific processing proteases 0.0196154515136496 200 42 4 0.0952380952380952 0.02
REAC REAC:R-HSA-8878171 Transcriptional regulation by RUNX1 0.0196154515136496 200 42 4 0.0952380952380952 0.02
REAC REAC:R-HSA-9711123 Cellular response to chemical stress 0.0196387711368777 35 125 3 0.024 0.0857142857142857
REAC REAC:R-HSA-3299685 Detoxification of Reactive Oxygen Species 0.0196387711368777 35 125 3 0.024 0.0857142857142857
REAC REAC:R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 0.0200757082489307 76 58 3 0.0517241379310345 0.0394736842105263
REAC REAC:R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 0.0200757082489307 126 67 4 0.0597014925373134 0.0317460317460317
REAC REAC:R-HSA-168255 Influenza Infection 0.0202569355339434 152 56 4 0.0714285714285714 0.0263157894736842
REAC REAC:R-HSA-168638 NOD1/2 Signaling Pathway 0.0202569355339434 36 124 3 0.0241935483870968 0.0833333333333333
REAC REAC:R-HSA-162906 HIV Infection 0.0205415096490359 226 83 6 0.072289156626506 0.0265486725663717
REAC REAC:R-HSA-9033241 Peroxisomal protein import 0.0208475771775426 60 75 3 0.04 0.05
REAC REAC:R-HSA-73887 Death Receptor Signalling 0.020969223587971 140 96 5 0.0520833333333333 0.0357142857142857
REAC REAC:R-HSA-68882 Mitotic Anaphase 0.0211339388017045 228 83 6 0.072289156626506 0.0263157894736842
REAC REAC:R-HSA-1474228 Degradation of the extracellular matrix 0.0213153795584618 140 62 4 0.0645161290322581 0.0285714285714286
REAC REAC:R-HSA-2555396 Mitotic Metaphase and Anaphase 0.0214340218538541 229 83 6 0.072289156626506 0.0262008733624454
REAC REAC:R-HSA-351202 Metabolism of polyamines 0.0241329682750617 58 83 3 0.036144578313253 0.0517241379310345
REAC REAC:R-HSA-193704 p75 NTR receptor-mediated signalling 0.0263162164894585 97 96 4 0.0416666666666667 0.0412371134020619
REAC REAC:R-HSA-8951664 Neddylation 0.0293447296840199 233 42 4 0.0952380952380952 0.0171673819742489
REAC REAC:R-HSA-9006925 Intracellular signaling by second messengers 0.029462239459362 289 52 5 0.0961538461538462 0.0173010380622837
REAC REAC:R-HSA-195721 Signaling by WNT 0.0306046018473509 292 52 5 0.0961538461538462 0.0171232876712329
REAC REAC:R-HSA-451927 Interleukin-2 family signaling 0.0332724429689626 44 127 3 0.0236220472440945 0.0681818181818182
REAC REAC:R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 0.0336242555200356 140 73 4 0.0547945205479452 0.0285714285714286
REAC REAC:R-HSA-109582 Hemostasis 0.0414902415646673 657 10 3 0.3 0.0045662100456621
REAC REAC:R-HSA-5673001 RAF/MAP kinase cascade 0.0414902415646673 264 42 4 0.0952380952380952 0.0151515151515152
REAC REAC:R-HSA-5684996 MAPK1/MAPK3 signaling 0.0419287262404942 269 42 4 0.0952380952380952 0.0148698884758364
REAC REAC:R-HSA-69620 Cell Cycle Checkpoints 0.0427618419987904 271 42 4 0.0952380952380952 0.014760147601476
REAC REAC:R-HSA-5688426 Deubiquitination 0.0448752552824295 276 42 4 0.0952380952380952 0.0144927536231884
REAC REAC:R-HSA-9607240 FLT3 Signaling 0.0458180490109416 278 42 4 0.0952380952380952 0.0143884892086331
REAC REAC:R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 0.0476723350275146 60 111 3 0.027027027027027 0.05
REAC REAC:R-HSA-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 0.0485173086747446 413 126 10 0.0793650793650794 0.0242130750605327
REAC REAC:R-HSA-194315 Signaling by Rho GTPases 0.0485173086747446 413 126 10 0.0793650793650794 0.0242130750605327
REAC REAC:R-HSA-68886 M Phase 0.0489670425044342 371 83 7 0.0843373493975904 0.0188679245283019
REAC REAC:R-HSA-186797 Signaling by PDGF 0.0495540558919753 54 127 3 0.0236220472440945 0.0555555555555556
TF TF:M09957 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN 7.55348483733901e-07 272 141 16 0.113475177304965 0.0588235294117647
TF TF:M08887 Factor: IRF; motif: NNGAAANTGAAANN 1.03162932131955e-06 1267 65 21 0.323076923076923 0.0165745856353591
TF TF:M04788 Factor: IRF-1; motif: STTTCACTTTCNNT 2.46860143509694e-06 536 63 14 0.222222222222222 0.0261194029850746
TF TF:M07216 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT 3.1823086782419e-06 440 141 18 0.127659574468085 0.0409090909090909
TF TF:M11685 Factor: IRF-8; motif: NCGAAACYGAAACYN 3.1823086782419e-06 1617 63 22 0.349206349206349 0.0136054421768707
TF TF:M11664 Factor: IRF-2; motif: NGAAASYGAAAS 3.1823086782419e-06 1651 68 23 0.338235294117647 0.013930950938825
TF TF:M00699_1 Factor: ICSBP; motif: RAARTGAAACTG; match class: 1 1.20269410658829e-05 47 3 3 1 0.0638297872340425
TF TF:M06507 Factor: ZFP90; motif: NGGGASTTTAKA 2.56124791459198e-05 40 4 3 0.75 0.075
TF TF:M11665 Factor: IRF-2; motif: NGAAASYGAAAS 2.60683613101463e-05 2396 68 26 0.382352941176471 0.0108514190317195
TF TF:M00063 Factor: IRF-2; motif: GAAAAGYGAAASY 0.000117855359003037 685 84 15 0.178571428571429 0.0218978102189781
TF TF:M11687 Factor: IRF-4; motif: NCGAAACCGAAACYN 0.000125398639023341 3595 85 36 0.423529411764706 0.0100139082058414
TF TF:M11686 Factor: IRF-4; motif: NYGAAASYGAAACYN 0.000130637212394268 3391 65 29 0.446153846153846 0.0085520495429077
TF TF:M09956 Factor: IRF-1; motif: NAAANNGAAASTGAAASNRN 0.000190521446935155 317 76 10 0.131578947368421 0.0315457413249211
TF TF:M00971 Factor: Ets; motif: ACTTCCTS 0.000246340063217505 2349 144 39 0.270833333333333 0.016602809706258
TF TF:M04015_1 Factor: IRF-4; motif: NCGAAACCGAAACYA; match class: 1 0.000278884369995416 158 39 6 0.153846153846154 0.0379746835443038
TF TF:M11777 Factor: RXR-gamma; motif: NRGGTCAYGACCYN 0.000491898362028606 138 4 3 0.75 0.0217391304347826
TF TF:M11741_1 Factor: COUP-TF1; motif: RRGGTCRNTGACCYY; match class: 1 0.000491898362028606 1014 13 7 0.538461538461538 0.00690335305719921
TF TF:M04054 Factor: NF-kappaB; motif: AGGGGAWTCCCCT 0.000491898362028606 2924 79 29 0.367088607594937 0.00991792065663475
TF TF:M11783 Factor: RXR-beta; motif: RRGGTCATGACCYY 0.000529837827004168 144 4 3 0.75 0.0208333333333333
TF TF:M00208_1 Factor: NF-kappaB; motif: NGGGACTTTCCA; match class: 1 0.000619686643966863 604 143 17 0.118881118881119 0.0281456953642384
TF TF:M04020_1 Factor: IRF8; motif: NCGAAACCGAAACT; match class: 1 0.000711550535543061 45 41 4 0.0975609756097561 0.0888888888888889
TF TF:M09745_1 Factor: HELIOS; motif: RNARRRGGAASTGARAN; match class: 1 0.000862319482419363 495 91 12 0.131868131868132 0.0242424242424242
TF TF:M11683 Factor: IRF-8; motif: NCGAAACCGAAACYN 0.000868901878296383 4690 86 40 0.465116279069767 0.00852878464818763
TF TF:M00453_1 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN; match class: 1 0.000868901878296383 332 91 10 0.10989010989011 0.0301204819277108
TF TF:M11670 Factor: IRF-5; motif: NYGAAACCGAAACY 0.000868901878296383 871 7 5 0.714285714285714 0.00574052812858783
TF TF:M00691_1 Factor: ATF-1; motif: CYYTGACGTCA; match class: 1 0.000891462011924149 854 4 4 1 0.00468384074941452
TF TF:M09733 Factor: STAT2; motif: NRGAAANNGAAACTNA 0.000969636107477617 2842 85 29 0.341176470588235 0.0102040816326531
TF TF:M04146 Factor: TFAP2A; motif: YGCCCNNRGGCN 0.000969636107477617 6552 17 15 0.882352941176471 0.00228937728937729
TF TF:M01967_1 Factor: Pbx; motif: NKTGATTGACRKSN; match class: 1 0.000969636107477617 889 4 4 1 0.00449943757030371
TF TF:M07045 Factor: IRF-1; motif: NNRAAANNGAAASN 0.000978389961640688 535 60 10 0.166666666666667 0.0186915887850467
TF TF:M11596 Factor: GCMb; motif: ATGCGGGYN 0.00107227703534182 737 20 7 0.35 0.00949796472184532
TF TF:M00453 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN 0.00108274145038419 3082 131 41 0.312977099236641 0.0133030499675535
TF TF:M11745_1 Factor: COUP-TF1; motif: RAGGTCANTGACCTY; match class: 1 0.00110176899763178 1954 13 8 0.615384615384615 0.00409416581371546
TF TF:M11682 Factor: IRF-8; motif: NYGAAASYGAAACYN 0.00110176899763178 3795 85 34 0.4 0.00895915678524374
TF TF:M02107 Factor: NF-YC; motif: NRGCCAATYAGMGC 0.00110176899763178 1001 4 4 1 0.003996003996004
TF TF:M00258 Factor: ISGF-3; motif: CAGTTTCWCTTTYCC 0.00110176899763178 823 51 11 0.215686274509804 0.0133657351154313
TF TF:M00208 Factor: NF-kappaB; motif: NGGGACTTTCCA 0.00110176899763178 3757 71 30 0.422535211267606 0.0079850944902848
TF TF:M05946_1 Factor: PRDM16; motif: KGGTCATRACCM; match class: 1 0.00110176899763178 2282 29 13 0.448275862068966 0.00569675723049956
TF TF:M11800_1 Factor: NR1B2; motif: RAGGTCRTGACCTY; match class: 1 0.00110176899763178 987 7 5 0.714285714285714 0.00506585612968592
TF TF:M00772 Factor: IRF; motif: RRAANTGAAASYGNV 0.00110176899763178 1029 85 16 0.188235294117647 0.0155490767735666
TF TF:M11763_1 Factor: TR2; motif: RRGGTCRYGACCYY; match class: 1 0.00110176899763178 241 4 3 0.75 0.012448132780083
TF TF:M01023 Factor: HSF1; motif: NTTCTRGAAVNTTCTYM 0.00110176899763178 2721 77 26 0.337662337662338 0.0095553105475928
TF TF:M04013 Factor: HSFY1; motif: TTCGAANSRTTCGAA 0.00110176899763178 962 4 4 1 0.00415800415800416
TF TF:M07323 Factor: IRF-4; motif: KRAAMNGAAANYN 0.00125639583008378 938 95 16 0.168421052631579 0.0170575692963753
TF TF:M00054 Factor: NF-kappaB; motif: GGGAMTTYCC 0.00125639583008378 2444 144 37 0.256944444444444 0.015139116202946
TF TF:M03852_1 Factor: SREBP-2; motif: NTCACCYNNNN; match class: 1 0.00125639583008378 2246 57 19 0.333333333333333 0.00845948352626892
TF TF:M01023_1 Factor: HSF1; motif: NTTCTRGAAVNTTCTYM; match class: 1 0.00125639583008378 254 23 5 0.217391304347826 0.0196850393700787
TF TF:M11781 Factor: RXR-beta; motif: RRGGTCGTGACCYY 0.00125639583008378 261 4 3 0.75 0.0114942528735632
TF TF:M11763 Factor: TR2; motif: RRGGTCRYGACCYY 0.00138840065462351 279 4 3 0.75 0.010752688172043
TF TF:M03795 Factor: LXR;; motif: NTGACCKNNAGTRACCYNN 0.00142770627566319 6570 144 73 0.506944444444444 0.0111111111111111
TF TF:M04152_1 Factor: TFAP2C; motif: NGCCCNNRGGCA; match class: 1 0.00156690083017771 5580 14 12 0.857142857142857 0.0021505376344086
TF TF:M08887_1 Factor: IRF; motif: NNGAAANTGAAANN; match class: 1 0.00163355123327106 73 141 6 0.0425531914893617 0.0821917808219178
TF TF:M09629 Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN 0.00204540032817976 336 33 6 0.181818181818182 0.0178571428571429
TF TF:M01223_1 Factor: P50:P50; motif: NRGGGAMTNCCCN; match class: 1 0.00208096651231752 161 7 3 0.428571428571429 0.0186335403726708
TF TF:M11654_1 Factor: HSF1; motif: RGAANRTTCYRGAAN; match class: 1 0.00208096651231752 113 28 4 0.142857142857143 0.0353982300884956
TF TF:M11743_1 Factor: COUP-TF1; motif: RAGGTCANYGACCTY; match class: 1 0.00208096651231752 4014 13 10 0.769230769230769 0.00249128051818635
TF TF:M11684 Factor: IRF-8; motif: NYGAAACYGAAACTN 0.00235113423016877 4664 86 38 0.441860465116279 0.008147512864494
TF TF:M00972_1 Factor: IRF; motif: RAAANTGAAAN; match class: 1 0.00238031869197788 205 55 6 0.109090909090909 0.0292682926829268
TF TF:M11684_1 Factor: IRF-8; motif: NYGAAACYGAAACTN; match class: 1 0.00278422652057678 832 91 14 0.153846153846154 0.0168269230769231
TF TF:M11765_1 Factor: TR2; motif: NRGGTCRYGACCYN; match class: 1 0.00281918050338757 1431 4 4 1 0.00279524807826695
TF TF:M00775 Factor: NF-Y; motif: NNNNRRCCAATSR 0.00281918050338757 1428 4 4 1 0.00280112044817927
TF TF:M11813 Factor: PPARdelta; motif: NRRGGTCATGACCYYT 0.00297214736792203 387 4 3 0.75 0.00775193798449612
TF TF:M08957_1 Factor: NURR1:RXR-ALPHA; motif: NRGGTCRTTGACCYN; match class: 1 0.00309207914595068 3226 13 9 0.692307692307692 0.0027898326100434
TF TF:M04802_1 Factor: c-Fos; motif: ACTCACCA; match class: 1 0.00309207914595068 1481 4 4 1 0.00270087778528022
TF TF:M11811 Factor: PPARdelta; motif: NRRGGTCGYGACCYYN 0.00313874309607481 403 4 3 0.75 0.00744416873449132
TF TF:M11677 Factor: IRF-3; motif: NGGAAACNGAAACCGAAACN 0.00313874309607481 470 141 13 0.0921985815602837 0.0276595744680851
TF TF:M11741 Factor: COUP-TF1; motif: RRGGTCRNTGACCYY 0.00313874309607481 3249 13 9 0.692307692307692 0.00277008310249307
TF TF:M00691 Factor: ATF-1; motif: CYYTGACGTCA 0.00315313546639565 4489 113 45 0.398230088495575 0.0100245043439519
TF TF:M04001 Factor: GCM1; motif: NATGCGGGTAC 0.00315313546639565 388 20 5 0.25 0.0128865979381443
TF TF:M00339_1 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS; match class: 1 0.00315313546639565 1466 140 25 0.178571428571429 0.0170532060027285
TF TF:M00339 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS 0.00318685030643025 6806 141 72 0.51063829787234 0.0105789009697326
TF TF:M04020 Factor: IRF8; motif: NCGAAACCGAAACT 0.00318685030643025 992 60 12 0.2 0.0120967741935484
TF TF:M08884 Factor: GCM; motif: NNNNATGMGGGN 0.00318685030643025 1185 23 8 0.347826086956522 0.00675105485232068
TF TF:M09950_1 Factor: HSF1; motif: NRGAANNTTCYRGAA; match class: 1 0.00333299747668432 266 69 7 0.101449275362319 0.0263157894736842
TF TF:M11817_1 Factor: T3R-beta; motif: NRRGGTCRTGACCYYN; match class: 1 0.00333299747668432 1566 4 4 1 0.00255427841634738
TF TF:M07302 Factor: NF-Y; motif: RGCCAATCRGN 0.00337116777926581 1576 4 4 1 0.00253807106598985
TF TF:M10057_1 Factor: Six-1; motif: TGWAAYNTGAKMCN; match class: 1 0.00356099055566045 13 108 3 0.0277777777777778 0.230769230769231
TF TF:M09726 Factor: GATAD2A; motif: CCTKTG 0.00363397895283461 15191 135 122 0.903703703703704 0.00803107102889869
TF TF:M00287 Factor: NF-Y; motif: NNNRRCCAATSRGNNN 0.00363397895283461 1635 4 4 1 0.00244648318042813
TF TF:M10004 Factor: NF-kappaB2; motif: GGGRAANYCCC 0.00363397895283461 1073 66 13 0.196969696969697 0.0121155638397018
TF TF:M00051_1 Factor: NF-kappaB; motif: GGGGATYCCC; match class: 1 0.00363397895283461 2797 56 20 0.357142857142857 0.00715051841258491
TF TF:M01721 Factor: PUR1; motif: GGGNCAGNN 0.00374731878041494 9145 134 85 0.634328358208955 0.00929469655549481
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 0.00374731878041494 1657 4 4 1 0.0024140012070006
TF TF:M07100 Factor: HSF1; motif: NTTCTRGAANNTTCY 0.00396003795192975 3350 31 15 0.483870967741935 0.00447761194029851
TF TF:M02078 Factor: SPI1; motif: NGRGGAAGTN 0.00422824842848075 3506 144 45 0.3125 0.0128351397604107
TF TF:M06529 Factor: ZNF596; motif: NGGTCGGGAAAA 0.00422824842848075 48 31 3 0.0967741935483871 0.0625
TF TF:M11743 Factor: COUP-TF1; motif: RAGGTCANYGACCTY 0.00428652566124794 4545 13 10 0.769230769230769 0.0022002200220022
TF TF:M02106 Factor: NF-YA; motif: CRGCCAATCAGNRN 0.00432030648931677 1741 4 4 1 0.00229753015508329
TF TF:M04002 Factor: GCMb; motif: NATGCGGGTN 0.00438004019875132 1282 23 8 0.347826086956522 0.0062402496099844
TF TF:M00972 Factor: IRF; motif: RAAANTGAAAN 0.00438004019875132 1979 78 20 0.256410256410256 0.0101061141990905
TF TF:M03882_1 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC; match class: 1 0.00438004019875132 714 143 16 0.111888111888112 0.0224089635854342
TF TF:M11664_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 0.00457976818107731 140 141 7 0.049645390070922 0.05
TF TF:M04014 Factor: IRF3; motif: NNRRAANGGAAACCGAAACYR 0.00474481623218779 278 50 6 0.12 0.0215827338129496
TF TF:M09726_1 Factor: GATAD2A; motif: CCTKTG; match class: 1 0.00474481623218779 9052 125 79 0.632 0.0087273530711445
TF TF:M01733_1 Factor: MZF-1; motif: TGGGGAR; match class: 1 0.00476160495443744 4931 57 28 0.491228070175439 0.00567836138714257
TF TF:M11687_1 Factor: IRF-4; motif: NCGAAACCGAAACYN; match class: 1 0.00557186953094954 474 76 9 0.118421052631579 0.0189873417721519
TF TF:M00051 Factor: NF-kappaB; motif: GGGGATYCCC 0.00568325754641283 6413 53 31 0.584905660377358 0.00483393107749883
TF TF:M00965 Factor: LXR,; motif: YGAMCTNNASTRACCYN 0.00572221617393371 3793 144 47 0.326388888888889 0.01239124703401
TF TF:M00924_1 Factor: AP-1; motif: TGACTCANNSKN; match class: 1 0.00579493700477058 255 19 4 0.210526315789474 0.0156862745098039
TF TF:M09668 Factor: RelA-p65; motif: GGGRNTTTCCM 0.00589383929147847 3576 144 45 0.3125 0.0125838926174497
TF TF:M04713 Factor: GATA-1; motif: CCTTATCTS 0.00597067970368942 3463 45 19 0.422222222222222 0.00548657233612475
TF TF:M09816 Factor: NFYA; motif: RRCCAATCAGN 0.00614575210310692 1969 4 4 1 0.00203148806500762
TF TF:M01882 Factor: IRF-2; motif: NNRAAAGTGAAASNNA 0.00625394322847598 258 141 9 0.0638297872340425 0.0348837209302326
TF TF:M11685_1 Factor: IRF-8; motif: NCGAAACYGAAACYN; match class: 1 0.00632835381918446 118 41 4 0.0975609756097561 0.0338983050847458
TF TF:M04482 Factor: RARA; motif: ARRGGTCANSNGAGGTCA 0.00635378298357245 3852 143 47 0.328671328671329 0.0122014537902388
TF TF:M09903 Factor: elf5; motif: NNNANSAGGAAGTNN 0.00635378298357245 1243 125 20 0.16 0.0160901045856798
TF TF:M04054_1 Factor: NF-kappaB; motif: AGGGGAWTCCCCT; match class: 1 0.00635378298357245 1295 52 12 0.230769230769231 0.00926640926640927
TF TF:M09964_1 Factor: JunD; motif: NRTGAGTCAYN; match class: 1 0.00635378298357245 854 19 6 0.315789473684211 0.00702576112412178
TF TF:M04849_1 Factor: RelA-p65; motif: AAASTCCC; match class: 1 0.00643030251070802 1170 49 11 0.224489795918367 0.0094017094017094
TF TF:M11807 Factor: RAR-gamma; motif: RAGGTCATGACCTY 0.00660983080928144 2046 4 4 1 0.00195503421309873
TF TF:M11656_1 Factor: HSF1; motif: RGAANRTTCYRGAAN; match class: 1 0.00664551696518134 219 69 6 0.0869565217391304 0.0273972602739726
TF TF:M04738 Factor: ER-alpha; motif: AGGTCANMNTGACC 0.00667570480062527 4374 6 6 1 0.00137174211248285
TF TF:M03997 Factor: GATA3; motif: NGATAANN 0.00685970082679329 4301 44 21 0.477272727272727 0.00488258544524529
TF TF:M08918 Factor: GATA-3; motif: WGATAASN 0.00685970082679329 4301 44 21 0.477272727272727 0.00488258544524529
TF TF:M11595 Factor: GCMa; motif: RTGCGGGTN 0.00686021075890649 12117 54 46 0.851851851851852 0.00379631922092927
TF TF:M11805_1 Factor: RAR-gamma; motif: RAGGTCRTGACCTY; match class: 1 0.00695754409502005 632 4 3 0.75 0.00474683544303797
TF TF:M08964 Factor: NR1B1:RXR-ALPHA; motif: RRGGTCANNNNNRGGTCA 0.0070316642077182 7003 114 60 0.526315789473684 0.00856775667571041
TF TF:M07460 Factor: KLF3; motif: CCMCRCCCNG 0.00758635169286982 1437 23 8 0.347826086956522 0.00556715379262352
TF TF:M08952_1 Factor: NF-KAPPAB1; motif: NGGKRNTTYCCCN; match class: 1 0.00762679427929034 3457 61 23 0.377049180327869 0.00665316748625976
TF TF:M11803_1 Factor: NR1B2; motif: RAGGTCATGACCTN; match class: 1 0.00762679427929034 915 7 4 0.571428571428571 0.00437158469945355
TF TF:M09589_1 Factor: AR; motif: NGNACANNNTGTTCYNN; match class: 1 0.00779256446860075 1159 28 8 0.285714285714286 0.00690250215703192
TF TF:M04018 Factor: IRF7; motif: NCGAAARYGAAANT 0.00779256446860075 619 50 8 0.16 0.012924071082391
TF TF:M11679 Factor: IRF-7; motif: NCGAAANCGAAANYN 0.00779256446860075 622 141 14 0.099290780141844 0.022508038585209
TF TF:M12092 Factor: ZNF787; motif: TGCCTCAGTTTMCCN 0.0078384023153625 634 106 12 0.113207547169811 0.0189274447949527
TF TF:M03557 Factor: P50; motif: GGRRANTCCCNN 0.00794215833895593 4967 73 33 0.452054794520548 0.00664384940608013
TF TF:M10005 Factor: NF-YA; motif: NYRRCCAATCAGAR 0.0081259569430411 2225 4 4 1 0.00179775280898876
TF TF:M00085 Factor: ZID; motif: NGGCTCYATCAYC 0.00817239352285413 240 67 6 0.0895522388059701 0.025
TF TF:M11805 Factor: RAR-gamma; motif: RAGGTCRTGACCTY 0.00930067879363495 2310 4 4 1 0.00173160173160173
TF TF:M03805_1 Factor: YB-1; motif: CCAMTCNGMR; match class: 1 0.00938100504740669 3680 136 43 0.316176470588235 0.0116847826086957
TF TF:M00687 Factor: alpha-CP1; motif: CAGCCAATGAG 0.00942061434396944 2326 4 4 1 0.00171969045571797
TF TF:M08765 Factor: GATA-1; motif: NGATAAN 0.00947741959438799 3421 44 18 0.409090909090909 0.00526161940952938
TF TF:M07214 Factor: GATA3; motif: AGATAAGA 0.00947741959438799 3417 44 18 0.409090909090909 0.00526777875329236
TF TF:M03216 Factor: GATA-6; motif: AGATAAN 0.00947741959438799 3421 44 18 0.409090909090909 0.00526161940952938
TF TF:M00789 Factor: GATA; motif: WGATARN 0.00947741959438799 3421 44 18 0.409090909090909 0.00526161940952938
TF TF:M09950 Factor: HSF1; motif: NRGAANNTTCYRGAA 0.00985611893691675 2501 44 15 0.340909090909091 0.00599760095961615
TF TF:M09960 Factor: IRF-8; motif: NNAARRGGAASTGAAASTNN 0.0100367222676963 282 85 7 0.0823529411764706 0.024822695035461
TF TF:M00699 Factor: ICSBP; motif: RAARTGAAACTG 0.0100367222676963 1184 3 3 1 0.00253378378378378
TF TF:M10126 Factor: ZNF134; motif: GCCTNNNCTMATCAGKTGAAGG 0.0101804381078704 223 76 6 0.0789473684210526 0.0269058295964126
TF TF:M03547 Factor: ER-alpha; motif: TGACCYN 0.0104516396668598 4712 45 22 0.488888888888889 0.00466893039049236
TF TF:M11799 Factor: NR1B2; motif: RAGGTCAAAAGGTCAN 0.0105239474964853 1837 141 27 0.191489361702128 0.0146978769733261
TF TF:M03824 Factor: GCMb; motif: RCCCKCAT 0.0108314253401894 1550 23 8 0.347826086956522 0.00516129032258065
TF TF:M02107_1 Factor: NF-YC; motif: NRGCCAATYAGMGC; match class: 1 0.011453949427398 58 42 3 0.0714285714285714 0.0517241379310345
TF TF:M10157_1 Factor: ZNF554; motif: GCNGAGYCANNTRGNNNRCT; match class: 1 0.0115291126970851 65 94 4 0.0425531914893617 0.0615384615384615
TF TF:M04750 Factor: GR; motif: RGRACATTNTGTYC 0.0115291126970851 5323 31 18 0.580645161290323 0.00338155175652827
TF TF:M10006 Factor: NF-YC; motif: NNRRCCAATCAGNR 0.0115291126970851 2510 4 4 1 0.00159362549800797
TF TF:M08965 Factor: NR1B1:RXR-GAMMA; motif: RRGGTCANNNNNRGGTCA 0.0116023004043357 3981 132 44 0.333333333333333 0.0110524993720171
TF TF:M10061 Factor: Smad4; motif: NWGTCTGNCACCT 0.0117876938899865 3744 7 6 0.857142857142857 0.0016025641025641
TF TF:M04903_1 Factor: HNF-4alpha; motif: AGTCCAAR; match class: 1 0.0117876938899865 1534 9 5 0.555555555555556 0.00325945241199478
TF TF:M11732 Factor: PXR; motif: NYGAACYNNNYGMMCTN 0.0129157584082185 2795 6 5 0.833333333333333 0.00178890876565295
TF TF:M01172_1 Factor: PU.1; motif: NNNNYYYACTTCCTCTTTY; match class: 1 0.0132823165866246 580 125 12 0.096 0.0206896551724138
TF TF:M10080 Factor: STAT2; motif: RRGRAANNGAAACTGAAAN 0.0132823165866246 356 95 8 0.0842105263157895 0.0224719101123595
TF TF:M11655_1 Factor: HSF1; motif: NGAANGTTCKRGAAN; match class: 1 0.0132823165866246 93 69 4 0.0579710144927536 0.043010752688172
TF TF:M09967_1 Factor: AP-2rep; motif: NGGGGCGGGGC; match class: 1 0.0132823165866246 1379 6 4 0.666666666666667 0.00290065264684554
TF TF:M09745 Factor: HELIOS; motif: RNARRRGGAASTGARAN 0.0132823165866246 3582 85 29 0.341176470588235 0.00809603573422669
TF TF:M09969_1 Factor: EKLF; motif: NGGGYGKGGCNNGG; match class: 1 0.0132823165866246 1489 14 6 0.428571428571429 0.00402955003357958
TF TF:M10491_1 Factor: ZNF586; motif: CAGGCCYRGAGG; match class: 1 0.0133969638832216 7720 144 77 0.534722222222222 0.0099740932642487
TF TF:M03821_1 Factor: ER-beta; motif: ANNSTGACCYRGNN; match class: 1 0.0133969638832216 1368 3 3 1 0.00219298245614035
TF TF:M00775_1 Factor: NF-Y; motif: NNNNRRCCAATSR; match class: 1 0.0133969638832216 133 49 4 0.0816326530612245 0.0300751879699248
TF TF:M07256 Factor: FXR:RXR; motif: RGGTCANTGACCTN 0.0135545745654815 1642 13 6 0.461538461538462 0.00365408038976857
TF TF:M11755 Factor: HNF-4alpha; motif: RRGGTCAAAGTCCAN 0.0135676181750394 2266 143 31 0.216783216783217 0.0136804942630185
TF TF:M11656 Factor: HSF1; motif: RGAANRTTCYRGAAN 0.0135676181750394 2033 44 13 0.295454545454545 0.00639449090014757
TF TF:M11739 Factor: COUP-TF1; motif: RRGGTCRNTGACCTN 0.0136474892307087 2698 4 4 1 0.00148257968865827
TF TF:M04152 Factor: TFAP2C; motif: NGCCCNNRGGCA 0.013695896213168 7738 17 14 0.823529411764706 0.00180925303696045
TF TF:M07222_1 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR; match class: 1 0.0143607748420591 66 42 3 0.0714285714285714 0.0454545454545455
TF TF:M02111 Factor: NR1B2; motif: NTGACCY 0.0143630233931133 9671 15 14 0.933333333333333 0.00144762692586082
TF TF:M09737 Factor: ZNF644; motif: TCCWGCCTCTSN 0.014652606411019 7275 125 65 0.52 0.00893470790378007
TF TF:M03920_1 Factor: SP1; motif: RCCMCRCCCMC; match class: 1 0.0147233217535167 3020 134 36 0.26865671641791 0.0119205298013245
TF TF:M04750_1 Factor: GR; motif: RGRACATTNTGTYC; match class: 1 0.0148329043203087 1704 28 9 0.321428571428571 0.00528169014084507
TF TF:M00641_1 Factor: HSF; motif: TTCCMGARGYTTC; match class: 1 0.0148329043203087 387 69 7 0.101449275362319 0.0180878552971576
TF TF:M09957_1 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN; match class: 1 0.0148329043203087 22 131 3 0.0229007633587786 0.136363636363636
TF TF:M03557_1 Factor: P50; motif: GGRRANTCCCNN; match class: 1 0.014851895737785 1292 36 9 0.25 0.00696594427244582
TF TF:M11686_1 Factor: IRF-4; motif: NYGAAASYGAAACYN; match class: 1 0.0148936564143764 452 141 11 0.0780141843971631 0.0243362831858407
TF TF:M04849 Factor: RelA-p65; motif: AAASTCCC 0.0148936564143764 6240 46 26 0.565217391304348 0.00416666666666667
TF TF:M11387 Factor: elf5; motif: NNNNMGGAAGTN 0.0148936564143764 2598 138 33 0.239130434782609 0.01270207852194
TF TF:M00634 Factor: GCM; motif: CNNRCCCGCATD 0.0150221120750846 2152 23 9 0.391304347826087 0.004182156133829
TF TF:M00272 Factor: p53; motif: NGRCWTGYCY 0.0150221120750846 4151 86 32 0.372093023255814 0.00770898578655746
TF TF:M11671 Factor: IRF-5; motif: NCGAAACCGAAACY 0.0154670117737569 389 33 5 0.151515151515152 0.012853470437018
TF TF:M08896 Factor: SIP1; motif: MRDSCAGGTGKCMCM 0.0154683127073514 669 30 6 0.2 0.00896860986547085
TF TF:M11759 Factor: HNF-4alpha; motif: RRGGTCAAAGTCCAN 0.0154683127073514 2090 143 29 0.202797202797203 0.0138755980861244
TF TF:M05528 Factor: ZAC; motif: KGWTGGGSAT 0.0156512030763251 147 131 6 0.0458015267175573 0.0408163265306122
TF TF:M11998 Factor: NF-kappaB2; motif: NGGGGAANYACCN 0.0160841587754676 283 69 6 0.0869565217391304 0.0212014134275618
TF TF:M04473 Factor: COUP-TF1; motif: RRGGTCAARAGGTCAN 0.0171167535149594 1104 112 16 0.142857142857143 0.0144927536231884
TF TF:M01151 Factor: DMRT7; motif: TTGTTACAWTKTKG 0.0172772799569257 1009 4 3 0.75 0.00297324083250743
TF TF:M07341 Factor: TORC2; motif: TGGGCTKKD 0.0172772799569257 4887 69 30 0.434782608695652 0.00613873542050338
TF TF:M05499 Factor: LKLF; motif: NGGGCGG 0.0172772799569257 7900 132 72 0.545454545454545 0.00911392405063291
TF TF:M01968_1 Factor: FOXO1; motif: TGTTKAC; match class: 1 0.0172772799569257 255 108 7 0.0648148148148148 0.0274509803921569
TF TF:M05386 Factor: KLF17; motif: NGGGCGG 0.0172772799569257 7900 132 72 0.545454545454545 0.00911392405063291
TF TF:M10013 Factor: LXR-alpha; motif: NNRRGGTYACTNNAGGNCA 0.0174631243361017 3171 144 39 0.270833333333333 0.0122989593188269
TF TF:M00340_1 Factor: c-Ets; motif: KRCAGGAARTRNKT; match class: 1 0.0176357866548292 906 74 11 0.148648648648649 0.0121412803532009
TF TF:M12339_1 Factor: BCL-6; motif: NTGCTTTCTAGGAATN; match class: 1 0.0179572298148154 645 72 9 0.125 0.013953488372093
TF TF:M09941 Factor: GR; motif: RGNACANMNTGTNCY 0.0179572298148154 5863 30 18 0.6 0.00307010063107624
TF TF:M11765 Factor: TR2; motif: NRGGTCRYGACCYN 0.0187744597780802 3058 4 4 1 0.0013080444735121
TF TF:M00641 Factor: HSF; motif: TTCCMGARGYTTC 0.0189043576065999 3599 28 13 0.464285714285714 0.0036121144762434
TF TF:M11800 Factor: NR1B2; motif: RAGGTCRTGACCTY 0.01895076651658 3716 10 7 0.7 0.00188374596340151
TF TF:M03869_1 Factor: Fra-1; motif: TGACTCAN; match class: 1 0.0190316950466399 418 19 4 0.210526315789474 0.00956937799043062
TF TF:M11727 Factor: NF-1B; motif: NTTGGCNNNNTGCCARN 0.0190316950466399 75 101 4 0.0396039603960396 0.0533333333333333
TF TF:M00721 Factor: CACCC-binding; motif: CANCCNNWGGGTGDGG 0.0190316950466399 2925 106 29 0.273584905660377 0.00991452991452992
TF TF:M03882 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC 0.0193757825089738 4474 72 29 0.402777777777778 0.00648189539561913
TF TF:M11745 Factor: COUP-TF1; motif: RAGGTCANTGACCTY 0.0194457503306667 5058 19 12 0.631578947368421 0.00237247924080664
TF TF:M09965_1 Factor: c-Jun; motif: NRTGAGTCAYN; match class: 1 0.0194457503306667 681 21 5 0.238095238095238 0.00734214390602056
TF TF:M11093 Factor: USF1; motif: ANCATGTGACN 0.0194842192438815 2820 85 24 0.282352941176471 0.00851063829787234
TF TF:M07611_1 Factor: p54NRB; motif: GRNNNMGGATGRMNNCGGA; match class: 1 0.0195569973060344 1645 6 4 0.666666666666667 0.00243161094224924
TF TF:M09724 Factor: DATF1; motif: SNGGRRGCWGNGGG 0.0197275726143038 8400 144 81 0.5625 0.00964285714285714
TF TF:M00774 Factor: NF-kappaB; motif: NGGGANTTYCCMNNNN 0.0201118895272632 1818 144 26 0.180555555555556 0.0143014301430143
TF TF:M01783_1 Factor: SP2; motif: GGGCGGGAC; match class: 1 0.0205292815954851 4333 134 46 0.343283582089552 0.0106162012462497
TF TF:M09940 Factor: GATA-6; motif: NNAGATAAGANAA 0.0205968251693919 2856 43 15 0.348837209302326 0.00525210084033613
TF TF:M06202_1 Factor: ZXDB; motif: NAGGGTG; match class: 1 0.0206380908872998 2007 31 10 0.32258064516129 0.0049825610363727
TF TF:M04679 Factor: USF2; motif: GTCACGTGA 0.0206380908872998 1577 98 18 0.183673469387755 0.0114140773620799
TF TF:M11676 Factor: IRF-3; motif: NGGAAANGGAAASNGAAACN 0.0206380908872998 562 85 9 0.105882352941176 0.0160142348754448
TF TF:M11803 Factor: NR1B2; motif: RAGGTCATGACCTN 0.0206380908872998 3194 4 4 1 0.00125234815278647
TF TF:M06203_1 Factor: ZXDA; motif: NAGGGTG; match class: 1 0.0206380908872998 2007 31 10 0.32258064516129 0.0049825610363727
TF TF:M01165_1 Factor: Elk-1; motif: RACCGGAAGTR; match class: 1 0.0206380908872998 2185 5 4 0.8 0.00183066361556064
TF TF:M08964_1 Factor: NR1B1:RXR-ALPHA; motif: RRGGTCANNNNNRGGTCA; match class: 1 0.0206481296474001 1827 114 22 0.192982456140351 0.0120415982484948
TF TF:M01858 Factor: AP-2beta; motif: GCNNNGGSCNGVGGGN 0.0207282150444707 7418 13 11 0.846153846153846 0.00148287948234025
TF TF:M00490 Factor: Bach2; motif: SRTGAGTCANC 0.0207282150444707 568 15 4 0.266666666666667 0.00704225352112676
TF TF:M06191_1 Factor: ZXDB; motif: NGGGGTC; match class: 1 0.0207282150444707 1279 120 18 0.15 0.0140734949179046
TF TF:M06190_1 Factor: ZXDA; motif: NGGGGTC; match class: 1 0.0207282150444707 1279 120 18 0.15 0.0140734949179046
TF TF:M02111_1 Factor: NR1B2; motif: NTGACCY; match class: 1 0.021101833751907 3323 14 8 0.571428571428571 0.00240746313572073
TF TF:M00113 Factor: CREB; motif: NNGNTGACGTNN 0.0214055305601348 4801 139 51 0.366906474820144 0.0106227869193918
TF TF:M11819 Factor: T3R-beta; motif: RTGACCTYACRTGACCTYA 0.0214934512953095 6924 126 62 0.492063492063492 0.00895436164067013
TF TF:M07204_1 Factor: AR; motif: ARGAACANNNTGTNC; match class: 1 0.0214934512953095 963 16 5 0.3125 0.00519210799584631
TF TF:M11446 Factor: Elf-1; motif: RANSMGGAAGTR 0.0214934512953095 2915 138 35 0.253623188405797 0.0120068610634648
TF TF:M12000 Factor: AML3; motif: NNAACCGCAAWAACCGCAAN 0.0218010873920482 6798 53 30 0.566037735849057 0.00441306266548985
TF TF:M01724 Factor: T3R-alpha; motif: NNTSRGGTCAN 0.0220994590152229 2615 142 33 0.232394366197183 0.0126195028680688
TF TF:M12000_1 Factor: AML3; motif: NNAACCGCAAWAACCGCAAN; match class: 1 0.0220994590152229 1586 39 10 0.256410256410256 0.00630517023959647
TF TF:M07213 Factor: GATA2; motif: NNNTTCTTATCTSN 0.0220994590152229 3816 44 18 0.409090909090909 0.00471698113207547
TF TF:M06275 Factor: ZNF284; motif: NGGGGGTGGTGM 0.022222200302813 184 20 3 0.15 0.016304347826087
TF TF:M00693_1 Factor: E12; motif: RRCAGGTGNCV; match class: 1 0.0223125687312721 370 81 7 0.0864197530864197 0.0189189189189189
TF TF:M09621 Factor: GATA-1; motif: NTGNNNNNNNSAGATAAGR 0.0224251106551983 5505 45 23 0.511111111111111 0.0041780199818347
TF TF:M11796_1 Factor: NR1B1; motif: NRGGNCRTGACCTN; match class: 1 0.0227675478824473 4887 105 41 0.39047619047619 0.00838960507468795
TF TF:M00155 Factor: ARP-1; motif: TGARCCYTTGAMCCCW 0.0229364272098979 5581 142 58 0.408450704225352 0.010392402795198
TF TF:M08891 Factor: NFKAPPAB; motif: NNGGGANTTCCCN 0.0230857273457666 2110 52 14 0.269230769230769 0.00663507109004739
TF TF:M04595 Factor: SALL2; motif: GGGTGGG 0.023470991246815 13013 132 104 0.787878787878788 0.00799200799200799
TF TF:M03841 Factor: PEBP2beta; motif: TGTGGTY 0.0235582551039773 7720 48 30 0.625 0.0038860103626943
TF TF:M09969 Factor: EKLF; motif: NGGGYGKGGCNNGG 0.0235582551039773 4589 7 6 0.857142857142857 0.00130747439529309
TF TF:M11597 Factor: GCMb; motif: ATGCGGGTN 0.0236626715058831 1192 20 6 0.3 0.00503355704697987
TF TF:M00766 Factor: LXR; motif: TGACCGNNAGTRACCC 0.0236687186678939 1007 105 14 0.133333333333333 0.0139026812313803
TF TF:M00448 Factor: Zic1; motif: KGGGTGGTC 0.0237258959755251 10948 138 95 0.688405797101449 0.00867738399707709
TF TF:M11375_1 Factor: Spi-B; motif: NAWGCGGAAGTN; match class: 1 0.0240953183561775 234 130 7 0.0538461538461538 0.0299145299145299
TF TF:M11095 Factor: USF2; motif: RNCAYGTGACN 0.0240953183561775 2547 85 22 0.258823529411765 0.00863761287789556
TF TF:M07341_1 Factor: TORC2; motif: TGGGCTKKD; match class: 1 0.0243287211470091 884 36 7 0.194444444444444 0.00791855203619909
TF TF:M09591_1 Factor: AP-2gamma; motif: NTGSCCTGRGGSNN; match class: 1 0.0243287211470091 2821 144 35 0.243055555555556 0.0124069478908189
TF TF:M07409_1 Factor: BTEB2; motif: GCCCCRCCCH; match class: 1 0.0243287211470091 1829 6 4 0.666666666666667 0.00218698742482231
TF TF:M00733_1 Factor: SMAD4; motif: GKSRKKCAGMCANCY; match class: 1 0.0254685357932469 2823 139 34 0.244604316546763 0.0120439249025859
TF TF:M04490_1 Factor: RXRA; motif: RRGGTCATGACCYY; match class: 1 0.0261107373870629 3535 4 4 1 0.00113154172560113
TF TF:M09729 Factor: LUMAN; motif: CYCAGCYYCY 0.0271728505325719 10686 120 82 0.683333333333333 0.00767359161519745
TF TF:M09958 Factor: IRF-3; motif: RAAARGGAAANNGAAASNGA 0.0272904505492246 589 141 12 0.0851063829787234 0.0203735144312394
TF TF:M09964 Factor: JunD; motif: NRTGAGTCAYN 0.0273439594362451 5047 5 5 1 0.000990687537150783
TF TF:M08940_1 Factor: C-JUN:FRA-2; motif: NNRTGAGTCAYN; match class: 1 0.0273439594362451 772 21 5 0.238095238095238 0.00647668393782383
TF TF:M09595_1 Factor: BCL-11A; motif: NAAAGAGGAAGTGARAN; match class: 1 0.0276224428430139 494 83 8 0.0963855421686747 0.0161943319838057
TF TF:M00287_1 Factor: NF-Y; motif: NNNRRCCAATSRGNNN; match class: 1 0.0276224428430139 184 49 4 0.0816326530612245 0.0217391304347826
TF TF:M11807_1 Factor: RAR-gamma; motif: RAGGTCATGACCTY; match class: 1 0.0278859608395978 651 7 3 0.428571428571429 0.00460829493087558
TF TF:M11260 Factor: NF-E2p45; motif: NATGASTCATN 0.0279979634718791 198 21 3 0.142857142857143 0.0151515151515152
TF TF:M04213 Factor: JDP2; motif: ATGACTCAT 0.0279979634718791 198 21 3 0.142857142857143 0.0151515151515152
TF TF:M11260_1 Factor: NF-E2p45; motif: NATGASTCATN; match class: 1 0.0279979634718791 198 21 3 0.142857142857143 0.0151515151515152
TF TF:M08756 Factor: Bach1; motif: ATGACTCAT 0.0279979634718791 198 21 3 0.142857142857143 0.0151515151515152
TF TF:M00378_1 Factor: Pax-4; motif: NNNNNYCACCCB; match class: 1 0.0279979634718791 14711 139 119 0.856115107913669 0.00808918496363266
TF TF:M07204 Factor: AR; motif: ARGAACANNNTGTNC 0.0280465274978986 4906 84 34 0.404761904761905 0.0069302894415002
TF TF:M08575 Factor: GCMa:C/EBPbeta; motif: ATGCGGGTNNRTTGCGCAAY 0.0281140519911267 7026 46 27 0.58695652173913 0.00384286934244236
TF TF:M11655 Factor: HSF1; motif: NGAANGTTCKRGAAN 0.0282037322328143 1207 44 9 0.204545454545455 0.00745650372825186
TF TF:M01733 Factor: MZF-1; motif: TGGGGAR 0.0282037322328143 11391 17 16 0.941176470588235 0.00140461768062505
TF TF:M11658 Factor: HSF4; motif: RGAANNTTCYRGAAN 0.0287347078119305 400 128 9 0.0703125 0.0225
TF TF:M07266_1 Factor: p300; motif: CTGNCTYMAN; match class: 1 0.0289093400767428 2218 137 28 0.204379562043796 0.0126239855725879
TF TF:M08944_1 Factor: JUNB:C-JUN; motif: NATGACKCAT; match class: 1 0.0295850149054165 933 11 4 0.363636363636364 0.00428724544480171
TF TF:M09784 Factor: RELB; motif: NNATTCCCCNN 0.0300645428678037 5356 78 34 0.435897435897436 0.00634802091112771
TF TF:M05629 Factor: ZNF44; motif: KGATSGRGCCSC 0.0302583805634283 276 58 5 0.0862068965517241 0.0181159420289855
TF TF:M04681_1 Factor: JunD; motif: RTGACGTCA; match class: 1 0.030299301151951 1726 142 24 0.169014084507042 0.0139049826187717
TF TF:M09733_1 Factor: STAT2; motif: NRGAAANNGAAACTNA; match class: 1 0.0304534656003718 367 141 9 0.0638297872340425 0.0245231607629428
TF TF:M00380 Factor: Pax-4; motif: RAAAAWTANNNNNNNNNNNNNNNYCACNCC 0.0308205179090043 852 143 15 0.104895104895105 0.0176056338028169
TF TF:M00209 Factor: NF-Y; motif: NCTGATTGGYTASY 0.0308205179090043 3776 4 4 1 0.00105932203389831
TF TF:M08897 Factor: SMAD; motif: TGTCTGNNN 0.0326066888516183 4543 108 39 0.361111111111111 0.00858463570327977
TF TF:M07327 Factor: Nanog; motif: NTNTAATGSN 0.0328167383790718 1926 35 10 0.285714285714286 0.00519210799584631
TF TF:M03820 Factor: ER-alpha; motif: GGNNNNNNTGACCYN 0.0328866179177114 2765 123 30 0.24390243902439 0.0108499095840868
TF TF:M09746 Factor: HNRPUL1; motif: NCNCAGN 0.0328866179177114 13720 18 18 1 0.00131195335276968
TF TF:M07430_1 Factor: SNA; motif: NCACCTGCNN; match class: 1 0.0330876833881629 119 81 4 0.0493827160493827 0.0336134453781513
TF TF:M04863_1 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG; match class: 1 0.0333865320171812 8573 14 12 0.857142857142857 0.00139974338038026
TF TF:M04903 Factor: HNF-4alpha; motif: AGTCCAAR 0.0342303577316154 6987 9 8 0.888888888888889 0.0011449835408616
TF TF:M04706 Factor: RelA; motif: GGGRAWTYC 0.0343967633325793 2278 3 3 1 0.00131694468832309
TF TF:M04015 Factor: IRF-4; motif: NCGAAACCGAAACYA 0.0348820069400014 2038 63 15 0.238095238095238 0.00736015701668302
TF TF:M09817_1 Factor: PAX5; motif: RNGCGTGACCNN; match class: 1 0.0349815238569057 6170 127 56 0.440944881889764 0.00907617504051864
TF TF:M11272_1 Factor: JunB; motif: NATGASTCAYN; match class: 1 0.0351866328845429 221 21 3 0.142857142857143 0.0135746606334842
TF TF:M10074_1 Factor: Spi-B; motif: NRAAAGAGGAAGTGARA; match class: 1 0.0354718684027355 75 132 4 0.0303030303030303 0.0533333333333333
TF TF:M02078_1 Factor: SPI1; motif: NGRGGAAGTN; match class: 1 0.0354718684027355 370 144 9 0.0625 0.0243243243243243
TF TF:M00446 Factor: Spz1; motif: DNNGGRGGGWWNNNN 0.0359786311157133 8655 14 12 0.857142857142857 0.00138648180242634
TF TF:M11665_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 0.0363538220875758 246 41 4 0.0975609756097561 0.016260162601626
TF TF:M12345 Factor: Zbtb37; motif: NYACCGCRNTCACCGCR 0.0367825058700313 5505 5 5 1 0.000908265213442325
TF TF:M10477_1 Factor: ZNF436; motif: TCCTCCAGGAAGCCY; match class: 1 0.0367825058700313 8681 14 12 0.857142857142857 0.00138232922474369
TF TF:M00203 Factor: GATA-X; motif: NGATAAGNMNN 0.0369790861294324 3713 44 17 0.386363636363636 0.00457850794505791
TF TF:M09625_1 Factor: GR; motif: RGNACANKNTGTNCY; match class: 1 0.0370670226860771 4205 30 14 0.466666666666667 0.00332936979785969
TF TF:M09622 Factor: GATA-2; motif: NSAGATAAGNN 0.0370670226860771 3044 44 15 0.340909090909091 0.00492772667542707
TF TF:M10170 Factor: ZNF85; motif: ANAGAARWCTGMWGKAATCT 0.0371102068194778 181 138 6 0.0434782608695652 0.0331491712707182
TF TF:M08302_1 Factor: FOXO1A:Net; motif: RWMAACAGGAAGTN; match class: 1 0.0371413104173577 2779 5 4 0.8 0.00143936667866139
TF TF:M11445_1 Factor: Elf-1; motif: NANCAGGAAGTR; match class: 1 0.0372644332728772 83 122 4 0.0327868852459016 0.0481927710843374
TF TF:M09615_1 Factor: Fra-1; motif: NRTGACTCATN; match class: 1 0.0372693398567952 559 19 4 0.210526315789474 0.00715563506261181
TF TF:M00796_1 Factor: USF; motif: NRCCACGTGASN; match class: 1 0.0373249645363292 525 84 8 0.0952380952380952 0.0152380952380952
TF TF:M08938_1 Factor: C-JUN:FRA-1; motif: NNATGACTCATNN; match class: 1 0.037760296610559 459 11 3 0.272727272727273 0.0065359477124183
TF TF:M07222 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR 0.0378839143900312 714 49 7 0.142857142857143 0.00980392156862745
TF TF:M11682_1 Factor: IRF-8; motif: NYGAAASYGAAACYN; match class: 1 0.0380063208536313 543 141 11 0.0780141843971631 0.0202578268876611
TF TF:M08623_1 Factor: rfx3:SRF; motif: TRGCAACNNNNNCCNWATANGGN; match class: 1 0.0380063208536313 8140 18 14 0.777777777777778 0.00171990171990172
TF TF:M11374_1 Factor: Spi-B; motif: NAWGRGGAAGTR; match class: 1 0.0380063208536313 202 125 6 0.048 0.0297029702970297
TF TF:M11386 Factor: elf5; motif: AANNAGGAAGTR 0.0383181632545838 678 66 8 0.121212121212121 0.0117994100294985
TF TF:M11988 Factor: NFATc3; motif: NTTTCCRYGGAAAN 0.0384358870492329 7175 9 8 0.888888888888889 0.00111498257839721
TF TF:M11218_1 Factor: CREB1; motif: NRTGAYGCGTN; match class: 1 0.0387747504635167 2438 3 3 1 0.00123051681706317
TF TF:M11299_1 Factor: jdp2; motif: NRTGASTCAYN; match class: 1 0.0388308304504984 235 21 3 0.142857142857143 0.0127659574468085
TF TF:M11388 Factor: elf5; motif: AANRAGGAAGTR 0.0388459872717388 660 100 10 0.1 0.0151515151515152
TF TF:M05467_1 Factor: Sall1; motif: NGGTCCKRGKRA; match class: 1 0.0391913128573613 568 97 9 0.0927835051546392 0.0158450704225352
TF TF:M11479 Factor: AP-2alpha; motif: NGCCTNAGGCN 0.0391913128573613 4568 144 49 0.340277777777778 0.0107267950963222
TF TF:M08933_1 Factor: JUND:C-FOS; motif: NNATGAGTCATNN; match class: 1 0.0394975128955313 1312 21 6 0.285714285714286 0.00457317073170732
TF TF:M03877_1 Factor: MASH-1; motif: YMMCACCTGCY; match class: 1 0.0404661410697234 61 81 3 0.037037037037037 0.0491803278688525
TF TF:M03852 Factor: SREBP-2; motif: NTCACCYNNNN 0.0404661410697234 8142 144 77 0.534722222222222 0.00945713583886023
TF TF:M01273 Factor: SP4; motif: SCCCCGCCCCS 0.0404661410697234 3296 7 5 0.714285714285714 0.00151699029126214
TF TF:M00655 Factor: PEA3; motif: ACWTCCK 0.0405052633488292 9452 128 78 0.609375 0.00825222175201016
TF TF:M02106_1 Factor: NF-YA; motif: CRGCCAATCAGNRN; match class: 1 0.0406184299484833 217 49 4 0.0816326530612245 0.0184331797235023
TF TF:M07100_1 Factor: HSF1; motif: NTTCTRGAANNTTCY; match class: 1 0.0414189500669423 514 69 7 0.101449275362319 0.0136186770428016
TF TF:M01888 Factor: Smad3; motif: NGNCAGACASNNN 0.0415154340842981 4104 28 13 0.464285714285714 0.00316764132553606
TF TF:M00008_1 Factor: Sp1; motif: GGGGCGGGGT; match class: 1 0.0424427307085445 4937 14 9 0.642857142857143 0.00182296941462427
TF TF:M09837 Factor: ZNF449; motif: NNNAGCCCARCC 0.0424818344062752 4264 4 4 1 0.000938086303939962
TF TF:M11445 Factor: Elf-1; motif: NANCAGGAAGTR 0.0424818344062752 1689 101 18 0.178217821782178 0.0106571936056838
TF TF:M03818_1 Factor: egr-3; motif: GTGGGY; match class: 1 0.0428831347614946 6724 114 54 0.473684210526316 0.00803093396787626
TF TF:M09624 Factor: GATA-6; motif: NNNAGATAAGAWAN 0.0428831347614946 3203 43 15 0.348837209302326 0.00468310958476428
TF TF:M04926 Factor: REST; motif: AAGGTGCT 0.0428831347614946 6325 40 22 0.55 0.00347826086956522
TF TF:M09590 Factor: AP-2alpha; motif: NTNSCCTGRGGSNAN 0.0428831347614946 5211 144 54 0.375 0.0103626943005181
TF TF:M03551_1 Factor: JunB; motif: TGACTCAN; match class: 1 0.0429218682006214 599 19 4 0.210526315789474 0.00667779632721202
TF TF:M09862 Factor: ZNF614; motif: NCYCWGCCYYNNN 0.0429218682006214 9361 122 74 0.60655737704918 0.00790513833992095
TF TF:M02280_1 Factor: AP1; motif: TGACTCA; match class: 1 0.0429218682006214 599 19 4 0.210526315789474 0.00667779632721202
TF TF:M11815_1 Factor: T3R-beta; motif: NNRGGTCRTGACCYNN; match class: 1 0.04319495026662 1675 4 3 0.75 0.0017910447761194
TF TF:M04679_1 Factor: USF2; motif: GTCACGTGA; match class: 1 0.0433789671788336 676 84 9 0.107142857142857 0.0133136094674556
TF TF:M03812 Factor: arnt; motif: CACGYA 0.0433931731070254 4330 4 4 1 0.00092378752886836
TF TF:M11216_1 Factor: CREB1; motif: NRTGATGTCAYN; match class: 1 0.0433931731070254 1220 128 17 0.1328125 0.0139344262295082
TF TF:M07115 Factor: NF-YB; motif: NNNYNRRCCAATCAG 0.043640229426458 529 51 6 0.117647058823529 0.0113421550094518
TF TF:M10963 Factor: RHOXF1; motif: NGGATCAN 0.043640229426458 2641 138 31 0.22463768115942 0.0117379780386217
TF TF:M00378 Factor: Pax-4; motif: NNNNNYCACCCB 0.0436534961319208 17858 139 135 0.971223021582734 0.0075596371374174
TF TF:M00631 Factor: FXR:RXR-alpha; motif: CAAGGTSAWTAACC 0.0442036292284529 3541 55 19 0.345454545454545 0.00536571589946343
TF TF:M03877 Factor: MASH-1; motif: YMMCACCTGCY 0.0442036292284529 1133 115 15 0.130434782608696 0.0132391879964696
TF TF:M01273_1 Factor: SP4; motif: SCCCCGCCCCS; match class: 1 0.0442036292284529 1016 6 3 0.5 0.00295275590551181
TF TF:M10105 Factor: USF1; motif: NGTCACGTGRNS 0.0442036292284529 2407 102 23 0.225490196078431 0.0095554632322393
TF TF:M00747_1 Factor: IRF-1; motif: TTCACTT; match class: 1 0.0444996310433521 933 40 7 0.175 0.007502679528403
TF TF:M09923_1 Factor: Fra-2; motif: NNRTGAGTCAYN; match class: 1 0.044792854969185 614 19 4 0.210526315789474 0.00651465798045603
TF TF:M00183_1 Factor: c-Myb; motif: NNNAACTGNC; match class: 1 0.0451971449380106 228 118 6 0.0508474576271186 0.0263157894736842
TF TF:M08392_1 Factor: A-Myb:TBR2; motif: NNGTGNNNAACGG; match class: 1 0.0457767752524194 111 101 4 0.0396039603960396 0.036036036036036
TF TF:M08453_1 Factor: ERF:SREBP-2; motif: NSCGGAARTCACGTGAT; match class: 1 0.0460003052885211 3729 88 28 0.318181818181818 0.00750871547331724
TF TF:M01599 Factor: FOXP3; motif: RTAAACAA 0.0460086671352354 1744 4 3 0.75 0.00172018348623853
TF TF:M09609 Factor: ER-alpha; motif: NNAGGTCANNNTGNCCN 0.0461845005889151 2059 126 24 0.19047619047619 0.0116561437591064
TF TF:M02013_1 Factor: HNF-1alpha; motif: RGTTAATNWTT; match class: 1 0.0461845005889151 90 60 3 0.05 0.0333333333333333
TF TF:M11654 Factor: HSF1; motif: RGAANRTTCYRGAAN 0.0461845005889151 1353 44 9 0.204545454545455 0.00665188470066519
TF TF:M03818 Factor: egr-3; motif: GTGGGY 0.0462837830182717 13384 115 92 0.8 0.0068738792588165
TF TF:M00187_1 Factor: USF; motif: GYCACGTGNC; match class: 1 0.0464756979102815 1528 87 15 0.172413793103448 0.00981675392670157
TF TF:M04814 Factor: RelA-p65; motif: AAATCCCCT 0.0464756979102815 4528 8 6 0.75 0.00132508833922261
TF TF:M09657 Factor: Smad4; motif: NTGTCTNNCACCT 0.0469925676776146 2405 6 4 0.666666666666667 0.00166320166320166
TF TF:M00955_1 Factor: GR; motif: NNNNNNNGKACNNNNTGTTCTNNNNNN; match class: 1 0.0472008957586303 754 26 5 0.192307692307692 0.00663129973474801
TF TF:M08775_1 Factor: IRF-2; motif: NAANYGAAASYR; match class: 1 0.0475021683725496 2761 3 3 1 0.00108656283955089
TF TF:M08825 Factor: NF-1B; motif: KCCAGANWN 0.0475345212963329 5811 17 11 0.647058823529412 0.00189296162450525
TF TF:M04053_1 Factor: NFATc1; motif: TTTTCCATGGAAAN; match class: 1 0.0478367658274888 5896 43 22 0.511627906976744 0.00373134328358209
TF TF:M08895 Factor: PITX; motif: TAATCCCN 0.0482170720038408 854 124 13 0.104838709677419 0.0152224824355972
TF TF:M00649 Factor: MAZ; motif: GGGGAGGG 0.0482768026266234 9327 140 83 0.592857142857143 0.00889889567921089
TF TF:M01855_1 Factor: AHR; motif: CACGCN; match class: 1 0.048571419870128 2796 3 3 1 0.00107296137339056
TF TF:M03838 Factor: Otx1; motif: WASTAATCC 0.0489303332156263 527 37 5 0.135135135135135 0.0094876660341556
TF TF:M10888 Factor: PRX-2; motif: CTAATTAN 0.0489423333028986 493 76 7 0.0921052631578947 0.0141987829614604
TF TF:M10952 Factor: isx; motif: CTAATTAN 0.0489423333028986 493 76 7 0.0921052631578947 0.0141987829614604
TF TF:M12076 Factor: ZNF342; motif: NRGTGGWCANT 0.0491714858837543 1510 14 5 0.357142857142857 0.0033112582781457
TF TF:M09771 Factor: GATA6; motif: NNNAGATAAGANN 0.0497172735972592 2882 44 14 0.318181818181818 0.00485773768216516
TF TF:M11739_1 Factor: COUP-TF1; motif: RRGGTCRNTGACCTN; match class: 1 0.0497172735972592 975 13 4 0.307692307692308 0.0041025641025641
WP WP:WP2328 Allograft Rejection 8.2531869830754e-09 88 32 9 0.28125 0.102272727272727
WP WP:WP4217 Ebola Virus Pathway on Host 8.2531869830754e-09 130 54 12 0.222222222222222 0.0923076923076923
WP WP:WP183 Proteasome Degradation 1.46426089830661e-08 64 49 9 0.183673469387755 0.140625
WP WP:WP619 Type II interferon signaling (IFNG) 2.01096358478076e-06 37 41 6 0.146341463414634 0.162162162162162
WP WP:WP4877 Host-pathogen interaction of human corona viruses - MAPK signaling 0.00174227833223667 36 16 3 0.1875 0.0833333333333333
WP WP:WP4197 The human immune response to tuberculosis 0.00174227833223667 23 141 5 0.0354609929078014 0.217391304347826
WP WP:WP3937 Microglia Pathogen Phagocytosis Pathway 0.00174227833223667 40 125 6 0.048 0.15
WP WP:WP4146 Macrophage markers 0.00205847714269375 9 74 3 0.0405405405405405 0.333333333333333
WP WP:WP3945 TYROBP Causal Network 0.0352586797651099 63 100 5 0.05 0.0793650793650794
WP WP:WP395 IL-4 Signaling Pathway 0.0382330966908958 55 127 5 0.0393700787401575 0.0909090909090909
WP WP:WP2037 Prolactin Signaling Pathway 0.0382330966908958 76 26 3 0.115384615384615 0.0394736842105263
WP WP:WP167 Eicosanoid Synthesis 0.0382330966908958 26 70 3 0.0428571428571429 0.115384615384615

pMA02 transcription factor target enrichment of top program genes

TF enrichment of pMA02
TFs corrosponding to activation of pMA02. (Left) pearson correlation of TF expression and gene expression program activatity in Mast cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.