pEpiTp16 program activity among Epithelial cells

Activation of pEpiTp16
pEpiTp16 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpiTp16 by different cell subtypes
pEpiTp16 gene program activation among cells of different subtypes (Epithelial cells).

pEpiTp16 top program genes

Top genes of pEpiTp16 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpiTp16 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpiTp16
pEpiTp16 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:3055 Nop56p-associated pre-rRNA complex 1.054891424417e-15 104 26 15 0.576923076923077 0.144230769230769
CORUM CORUM:306 Ribosome, cytoplasmic 5.98922953158582e-11 80 26 11 0.423076923076923 0.1375
CORUM CORUM:308 60S ribosomal subunit, cytoplasmic 2.77012823396351e-10 47 26 9 0.346153846153846 0.191489361702128
CORUM CORUM:742 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7) 0.00265824827933939 12 34 3 0.0882352941176471 0.25
CORUM CORUM:1097 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7, PCID1) 0.00274687606262979 13 34 3 0.0882352941176471 0.230769230769231
CORUM CORUM:5380 TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) 0.0163739498418957 25 37 3 0.0810810810810811 0.12
GO:BP GO:0006412 translation 5.26846233463497e-22 764 63 30 0.476190476190476 0.0392670157068063
GO:BP GO:0006413 translational initiation 5.26846233463497e-22 201 34 17 0.5 0.0845771144278607
GO:BP GO:0043043 peptide biosynthetic process 9.31537622859302e-22 790 63 30 0.476190476190476 0.0379746835443038
GO:BP GO:0043604 amide biosynthetic process 5.91253911438249e-20 932 37 24 0.648648648648649 0.0257510729613734
GO:BP GO:0006518 peptide metabolic process 8.41152621416219e-20 955 37 24 0.648648648648649 0.025130890052356
GO:BP GO:0019080 viral gene expression 1.51828257880036e-18 199 35 15 0.428571428571429 0.0753768844221105
GO:BP GO:0043603 cellular amide metabolic process 2.80395648922053e-17 1241 37 24 0.648648648648649 0.0193392425463336
GO:BP GO:0002181 cytoplasmic translation 5.16229326715136e-17 103 34 12 0.352941176470588 0.116504854368932
GO:BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane 5.84174299811144e-17 96 26 11 0.423076923076923 0.114583333333333
GO:BP GO:0006613 cotranslational protein targeting to membrane 1.05724994157384e-16 102 26 11 0.423076923076923 0.107843137254902
GO:BP GO:0045047 protein targeting to ER 3.11030939802802e-16 113 26 11 0.423076923076923 0.0973451327433628
GO:BP GO:0072599 establishment of protein localization to endoplasmic reticulum 4.24199195295611e-16 117 26 11 0.423076923076923 0.094017094017094
GO:BP GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 6.92326697818138e-16 123 26 11 0.423076923076923 0.0894308943089431
GO:BP GO:0016032 viral process 7.03852347377439e-16 942 26 18 0.692307692307692 0.0191082802547771
GO:BP GO:0044403 biological process involved in symbiotic interaction 1.92903656208945e-15 1001 26 18 0.692307692307692 0.017982017982018
GO:BP GO:0006612 protein targeting to membrane 2.23775354038226e-15 204 26 12 0.461538461538462 0.0588235294117647
GO:BP GO:0070972 protein localization to endoplasmic reticulum 3.69314953517361e-15 146 26 11 0.423076923076923 0.0753424657534247
GO:BP GO:1901566 organonitrogen compound biosynthetic process 6.50839722914297e-15 1853 37 25 0.675675675675676 0.0134916351861846
GO:BP GO:0090150 establishment of protein localization to membrane 2.68930002703775e-14 351 26 13 0.5 0.037037037037037
GO:BP GO:0019083 viral transcription 3.50628500736157e-14 181 26 11 0.423076923076923 0.0607734806629834
GO:BP GO:0000956 nuclear-transcribed mRNA catabolic process 2.15710415368684e-13 214 26 11 0.423076923076923 0.0514018691588785
GO:BP GO:0006605 protein targeting 4.44883762974726e-13 441 26 13 0.5 0.0294784580498866
GO:BP GO:0006402 mRNA catabolic process 3.1613598825381e-12 384 26 12 0.461538461538462 0.03125
GO:BP GO:0022618 ribonucleoprotein complex assembly 7.19824547142626e-12 197 37 11 0.297297297297297 0.0558375634517767
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 7.19824547142626e-12 5017 37 32 0.864864864864865 0.00637831373330676
GO:BP GO:0034645 cellular macromolecule biosynthetic process 8.21461321329328e-12 5051 37 32 0.864864864864865 0.00633537913284498
GO:BP GO:0006401 RNA catabolic process 8.73365901575763e-12 424 26 12 0.461538461538462 0.0283018867924528
GO:BP GO:0071826 ribonucleoprotein complex subunit organization 9.44251594032461e-12 204 37 11 0.297297297297297 0.053921568627451
GO:BP GO:0009059 macromolecule biosynthetic process 1.07131223286667e-11 5114 37 32 0.864864864864865 0.00625733281188893
GO:BP GO:0034655 nucleobase-containing compound catabolic process 2.77784195447183e-11 567 28 13 0.464285714285714 0.0229276895943563
GO:BP GO:0046700 heterocycle catabolic process 5.7430284029767e-11 602 28 13 0.464285714285714 0.0215946843853821
GO:BP GO:0072657 protein localization to membrane 5.80997658292998e-11 665 26 13 0.5 0.0195488721804511
GO:BP GO:0044270 cellular nitrogen compound catabolic process 6.11618367142415e-11 608 28 13 0.464285714285714 0.0213815789473684
GO:BP GO:0019439 aromatic compound catabolic process 8.07815824344271e-11 623 28 13 0.464285714285714 0.0208667736757624
GO:BP GO:0022613 ribonucleoprotein complex biogenesis 8.65332914948796e-11 446 37 13 0.351351351351351 0.0291479820627803
GO:BP GO:1901361 organic cyclic compound catabolic process 1.32868642444896e-10 651 28 13 0.464285714285714 0.0199692780337942
GO:BP GO:0044249 cellular biosynthetic process 1.63275109498543e-10 6154 37 33 0.891891891891892 0.00536236594085148
GO:BP GO:1901576 organic substance biosynthetic process 2.54729979107844e-10 6248 37 33 0.891891891891892 0.00528169014084507
GO:BP GO:0072594 establishment of protein localization to organelle 2.61871453766755e-10 584 26 12 0.461538461538462 0.0205479452054795
GO:BP GO:0016071 mRNA metabolic process 3.70040108457591e-10 874 51 18 0.352941176470588 0.0205949656750572
GO:BP GO:0009058 biosynthetic process 3.71716435674003e-10 6340 37 33 0.891891891891892 0.00520504731861199
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 9.45248873680508e-10 2255 26 18 0.692307692307692 0.00798226164079823
GO:BP GO:0015031 protein transport 1.09333157290468e-09 1929 26 17 0.653846153846154 0.00881285640228098
GO:BP GO:0034641 cellular nitrogen compound metabolic process 1.17066353945781e-09 6563 55 44 0.8 0.00670425110467774
GO:BP GO:0015833 peptide transport 1.41352972874052e-09 1971 26 17 0.653846153846154 0.00862506341958397
GO:BP GO:0042255 ribosome assembly 1.41352972874052e-09 64 37 7 0.189189189189189 0.109375
GO:BP GO:0071705 nitrogen compound transport 1.41352972874052e-09 2322 26 18 0.692307692307692 0.00775193798449612
GO:BP GO:0042886 amide transport 1.85001594251989e-09 2007 26 17 0.653846153846154 0.00847035376183358
GO:BP GO:0045184 establishment of protein localization 2.26235067139882e-09 2035 26 17 0.653846153846154 0.00835380835380835
GO:BP GO:0006886 intracellular protein transport 3.20791382587821e-09 1186 26 14 0.538461538461538 0.0118043844856661
GO:BP GO:0042273 ribosomal large subunit biogenesis 3.68397189193731e-09 74 37 7 0.189189189189189 0.0945945945945946
GO:BP GO:0006820 anion transport 3.86571338701461e-09 2889 26 19 0.730769230769231 0.006576670128072
GO:BP GO:0010467 gene expression 1.78178700158715e-08 6179 37 31 0.837837837837838 0.00501699304094514
GO:BP GO:0071702 organic substance transport 2.30166391981347e-08 2766 26 18 0.692307692307692 0.00650759219088937
GO:BP GO:0034250 positive regulation of cellular amide metabolic process 3.33159957066719e-08 171 36 8 0.222222222222222 0.0467836257309941
GO:BP GO:0046907 intracellular transport 4.48830855278076e-08 1767 26 15 0.576923076923077 0.00848896434634975
GO:BP GO:0019081 viral translation 4.56562465475753e-08 16 63 5 0.0793650793650794 0.3125
GO:BP GO:0009057 macromolecule catabolic process 4.61545926280785e-08 1468 26 14 0.538461538461538 0.00953678474114441
GO:BP GO:0002183 cytoplasmic translational initiation 4.99815114252412e-08 35 63 6 0.0952380952380952 0.171428571428571
GO:BP GO:0044265 cellular macromolecule catabolic process 6.60468785657488e-08 1231 26 13 0.5 0.0105605199025183
GO:BP GO:0000027 ribosomal large subunit assembly 7.15022337833703e-08 29 37 5 0.135135135135135 0.172413793103448
GO:BP GO:0033365 protein localization to organelle 9.7579825882557e-08 1017 26 12 0.461538461538462 0.0117994100294985
GO:BP GO:0006811 ion transport 2.06757038766384e-07 3661 26 19 0.730769230769231 0.00518983884184649
GO:BP GO:0045727 positive regulation of translation 2.17198310672846e-07 140 36 7 0.194444444444444 0.05
GO:BP GO:0008104 protein localization 2.21607176388941e-07 2770 26 17 0.653846153846154 0.00613718411552347
GO:BP GO:0034613 cellular protein localization 2.30328905179978e-07 2014 26 15 0.576923076923077 0.00744786494538232
GO:BP GO:0033036 macromolecule localization 2.30328905179978e-07 3218 26 18 0.692307692307692 0.00559353635798633
GO:BP GO:0070727 cellular macromolecule localization 2.42966117035058e-07 2024 26 15 0.576923076923077 0.00741106719367589
GO:BP GO:0051649 establishment of localization in cell 2.65155707260184e-07 2813 26 17 0.653846153846154 0.00604337006754355
GO:BP GO:0010629 negative regulation of gene expression 4.46313962489915e-07 1460 26 13 0.5 0.0089041095890411
GO:BP GO:0006414 translational elongation 5.22681902699293e-07 141 62 8 0.129032258064516 0.0567375886524823
GO:BP GO:0075522 IRES-dependent viral translational initiation 8.47705582032965e-07 11 63 4 0.0634920634920635 0.363636363636364
GO:BP GO:0051641 cellular localization 9.98731198847515e-07 3541 26 18 0.692307692307692 0.00508330979949167
GO:BP GO:0006810 transport 1.12517947744435e-06 5224 26 21 0.807692307692308 0.00401990811638591
GO:BP GO:0042254 ribosome biogenesis 1.23197639262611e-06 307 46 9 0.195652173913043 0.0293159609120521
GO:BP GO:0043933 protein-containing complex subunit organization 1.31366398154277e-06 1963 63 23 0.365079365079365 0.0117167600611309
GO:BP GO:0034622 cellular protein-containing complex assembly 1.3506777790037e-06 1107 20 10 0.5 0.00903342366757001
GO:BP GO:0044267 cellular protein metabolic process 1.59005320923523e-06 5229 38 27 0.710526315789474 0.00516351118760757
GO:BP GO:0051234 establishment of localization 1.79767867992596e-06 5372 26 21 0.807692307692308 0.00390915860014892
GO:BP GO:1901575 organic substance catabolic process 3.69103898672265e-06 2267 28 15 0.535714285714286 0.00661667401852669
GO:BP GO:0006417 regulation of translation 3.77346973230351e-06 462 36 9 0.25 0.0194805194805195
GO:BP GO:0044260 cellular macromolecule metabolic process 3.99429423204026e-06 8390 38 33 0.868421052631579 0.00393325387365912
GO:BP GO:0065003 protein-containing complex assembly 5.50115752476447e-06 1680 20 11 0.55 0.00654761904761905
GO:BP GO:0044248 cellular catabolic process 5.57475980961068e-06 2347 28 15 0.535714285714286 0.0063911376224968
GO:BP GO:0010468 regulation of gene expression 7.81367843640937e-06 5196 36 25 0.694444444444444 0.00481139337952271
GO:BP GO:0034248 regulation of cellular amide metabolic process 1.21752449264596e-05 535 36 9 0.25 0.0168224299065421
GO:BP GO:0019538 protein metabolic process 1.5188177707056e-05 5808 38 27 0.710526315789474 0.00464876033057851
GO:BP GO:1901564 organonitrogen compound metabolic process 1.99219712445434e-05 6792 38 29 0.763157894736842 0.00426972909305065
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 2.96852282909189e-05 3241 27 16 0.592592592592593 0.00493674791730947
GO:BP GO:0051179 localization 3.43720368207234e-05 6901 33 26 0.787878787878788 0.00376756991740328
GO:BP GO:0009056 catabolic process 3.98016849080382e-05 2744 28 15 0.535714285714286 0.005466472303207
GO:BP GO:0001732 formation of cytoplasmic translation initiation complex 5.12966522089094e-05 16 34 3 0.0882352941176471 0.1875
GO:BP GO:0009892 negative regulation of metabolic process 7.4992642930219e-05 3479 27 16 0.592592592592593 0.00459902270767462
GO:BP GO:0001731 formation of translation preinitiation complex 0.000127435823749651 12 63 3 0.0476190476190476 0.25
GO:BP GO:0016070 RNA metabolic process 0.00015479907617046 4710 51 28 0.549019607843137 0.0059447983014862
GO:BP GO:0060255 regulation of macromolecule metabolic process 0.000193868583261586 6603 36 26 0.722222222222222 0.00393760411933969
GO:BP GO:0044237 cellular metabolic process 0.000261792342923182 10871 41 37 0.902439024390244 0.00340355073130347
GO:BP GO:0043170 macromolecule metabolic process 0.000261792342923182 9796 38 33 0.868421052631579 0.00336872192731727
GO:BP GO:0090304 nucleic acid metabolic process 0.00036624107565197 5226 51 29 0.568627450980392 0.00554917719096824
GO:BP GO:0044085 cellular component biogenesis 0.000370819544685119 3257 58 24 0.413793103448276 0.00736874424316856
GO:BP GO:0071353 cellular response to interleukin-4 0.000394891401736913 33 33 3 0.0909090909090909 0.0909090909090909
GO:BP GO:0070670 response to interleukin-4 0.000505139833023812 36 33 3 0.0909090909090909 0.0833333333333333
GO:BP GO:0006807 nitrogen compound metabolic process 0.000524297773711855 10078 55 45 0.818181818181818 0.00446517166104386
GO:BP GO:0010608 posttranscriptional regulation of gene expression 0.000567852170922799 896 62 12 0.193548387096774 0.0133928571428571
GO:BP GO:0044238 primary metabolic process 0.000569818816213106 10584 41 36 0.878048780487805 0.00340136054421769
GO:BP GO:0006139 nucleobase-containing compound metabolic process 0.000724749424122789 5746 51 30 0.588235294117647 0.00522102332057083
GO:BP GO:0031328 positive regulation of cellular biosynthetic process 0.000724749424122789 1967 36 13 0.361111111111111 0.00660904931367565
GO:BP GO:0071704 organic substance metabolic process 0.000825044450521009 11326 41 37 0.902439024390244 0.00326681970686915
GO:BP GO:0019222 regulation of metabolic process 0.000831842162941739 7148 36 26 0.722222222222222 0.00363738108561835
GO:BP GO:0009891 positive regulation of biosynthetic process 0.000857904219135021 2004 36 13 0.361111111111111 0.00648702594810379
GO:BP GO:0022607 cellular component assembly 0.000955570192897451 3010 58 22 0.379310344827586 0.00730897009966777
GO:BP GO:0046483 heterocycle metabolic process 0.00118901139157402 5904 51 30 0.588235294117647 0.00508130081300813
GO:BP GO:0006725 cellular aromatic compound metabolic process 0.00140033594449661 5956 51 30 0.588235294117647 0.00503693754197448
GO:BP GO:0010557 positive regulation of macromolecule biosynthetic process 0.00162555686640777 1851 41 13 0.317073170731707 0.00702323068611561
GO:BP GO:0015931 nucleobase-containing compound transport 0.00188701458966209 260 20 4 0.2 0.0153846153846154
GO:BP GO:2000112 regulation of cellular macromolecule biosynthetic process 0.00215068942073839 4071 44 21 0.477272727272727 0.0051584377302874
GO:BP GO:0010556 regulation of macromolecule biosynthetic process 0.00238871612997835 4102 44 21 0.477272727272727 0.00511945392491468
GO:BP GO:0008152 metabolic process 0.00271533912755919 11827 41 37 0.902439024390244 0.00312843493700854
GO:BP GO:1901360 organic cyclic compound metabolic process 0.00296565265637663 6201 51 30 0.588235294117647 0.00483792936623125
GO:BP GO:0006396 RNA processing 0.00322580842611523 964 51 10 0.196078431372549 0.0103734439834025
GO:BP GO:0070925 organelle assembly 0.00322815857833604 895 20 6 0.3 0.00670391061452514
GO:BP GO:0031326 regulation of cellular biosynthetic process 0.00415592622957803 4273 44 21 0.477272727272727 0.00491457992043061
GO:BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 0.00518167423084287 361 51 6 0.117647058823529 0.0166204986149584
GO:BP GO:0000398 mRNA splicing, via spliceosome 0.00518167423084287 361 51 6 0.117647058823529 0.0166204986149584
GO:BP GO:0009889 regulation of biosynthetic process 0.00533919662980088 4361 44 21 0.477272727272727 0.00481540930979133
GO:BP GO:0000375 RNA splicing, via transesterification reactions 0.00533919662980088 364 51 6 0.117647058823529 0.0164835164835165
GO:BP GO:0010628 positive regulation of gene expression 0.00653553819284863 1160 47 10 0.212765957446809 0.00862068965517241
GO:BP GO:0051348 negative regulation of transferase activity 0.00676454002799155 310 24 4 0.166666666666667 0.0129032258064516
GO:BP GO:0045471 response to ethanol 0.00728304260299822 142 23 3 0.130434782608696 0.0211267605633803
GO:BP GO:0048519 negative regulation of biological process 0.00799176783451275 5757 27 17 0.62962962962963 0.00295292687163453
GO:BP GO:0042274 ribosomal small subunit biogenesis 0.00833619601848187 74 46 3 0.0652173913043478 0.0405405405405405
GO:BP GO:0008284 positive regulation of cell population proliferation 0.0129133649333774 982 24 6 0.25 0.00610997963340122
GO:BP GO:0008380 RNA splicing 0.014788705033023 456 51 6 0.117647058823529 0.0131578947368421
GO:BP GO:0042176 regulation of protein catabolic process 0.0153027367640815 401 24 4 0.166666666666667 0.00997506234413965
GO:BP GO:0071363 cellular response to growth factor stimulus 0.0161712620459403 731 14 4 0.285714285714286 0.00547195622435021
GO:BP GO:0010033 response to organic substance 0.0165596005575325 3412 27 12 0.444444444444444 0.00351699882766706
GO:BP GO:0070848 response to growth factor 0.017516117895518 759 14 4 0.285714285714286 0.00527009222661397
GO:BP GO:0016043 cellular component organization 0.0176425984727432 6566 20 14 0.7 0.00213219616204691
GO:BP GO:0010035 response to inorganic substance 0.0181596391934736 575 9 3 0.333333333333333 0.00521739130434783
GO:BP GO:0071310 cellular response to organic substance 0.0189298166522065 2776 14 7 0.5 0.00252161383285303
GO:BP GO:0071840 cellular component organization or biogenesis 0.0221558322574411 6760 20 14 0.7 0.00207100591715976
GO:BP GO:0043462 regulation of ATPase activity 0.023348077547299 80 67 3 0.0447761194029851 0.0375
GO:BP GO:0006979 response to oxidative stress 0.0239355007004702 466 57 6 0.105263157894737 0.0128755364806867
GO:BP GO:0071345 cellular response to cytokine stimulus 0.0244021506678148 1132 11 4 0.363636363636364 0.00353356890459364
GO:BP GO:0048024 regulation of mRNA splicing, via spliceosome 0.024938501852729 119 47 3 0.0638297872340425 0.0252100840336134
GO:BP GO:0006397 mRNA processing 0.0249757372005505 532 51 6 0.117647058823529 0.0112781954887218
GO:BP GO:0097305 response to alcohol 0.0263186330473041 255 23 3 0.130434782608696 0.0117647058823529
GO:BP GO:0071824 protein-DNA complex subunit organization 0.0281068242118546 294 41 4 0.0975609756097561 0.0136054421768707
GO:BP GO:0051246 regulation of protein metabolic process 0.0289971862016391 2704 36 12 0.333333333333333 0.00443786982248521
GO:BP GO:0051223 regulation of protein transport 0.0291094312540485 586 11 3 0.272727272727273 0.00511945392491468
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.0294065587852368 3083 36 13 0.361111111111111 0.0042166720726565
GO:BP GO:0034097 response to cytokine 0.029546918229576 1226 11 4 0.363636363636364 0.0032626427406199
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.0300418928501793 3483 36 14 0.388888888888889 0.00401952339936836
GO:BP GO:0031329 regulation of cellular catabolic process 0.0302806815977912 866 24 5 0.208333333333333 0.00577367205542725
GO:BP GO:0070201 regulation of establishment of protein localization 0.0314579284861202 611 11 3 0.272727272727273 0.00490998363338789
GO:BP GO:0090087 regulation of peptide transport 0.0316582524020924 618 11 3 0.272727272727273 0.00485436893203883
GO:BP GO:0032984 protein-containing complex disassembly 0.0321553498474918 333 62 5 0.0806451612903226 0.015015015015015
GO:BP GO:0007569 cell aging 0.033564153605526 117 57 3 0.0526315789473684 0.0256410256410256
GO:BP GO:0031400 negative regulation of protein modification process 0.0360570875659761 578 24 4 0.166666666666667 0.0069204152249135
GO:BP GO:0006996 organelle organization 0.0366050091874691 4104 20 10 0.5 0.00243664717348928
GO:BP GO:0010639 negative regulation of organelle organization 0.0375198257271001 361 20 3 0.15 0.00831024930747922
GO:BP GO:0080135 regulation of cellular response to stress 0.0386377630786318 725 57 7 0.12280701754386 0.0096551724137931
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.0386377630786318 1477 36 8 0.222222222222222 0.00541638456330399
GO:BP GO:0043086 negative regulation of catalytic activity 0.0396181163496198 851 27 5 0.185185185185185 0.00587544065804935
GO:BP GO:0031325 positive regulation of cellular metabolic process 0.0398186727323321 3274 36 13 0.361111111111111 0.00397067806963958
GO:BP GO:0034728 nucleosome organization 0.0398567361089761 182 41 3 0.0731707317073171 0.0164835164835165
GO:BP GO:0070887 cellular response to chemical stimulus 0.0398567361089761 3393 14 7 0.5 0.00206307102858827
GO:BP GO:0050684 regulation of mRNA processing 0.0398567361089761 158 47 3 0.0638297872340425 0.0189873417721519
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 0.0398567361089761 5848 48 24 0.5 0.00410396716826265
GO:BP GO:0072331 signal transduction by p53 class mediator 0.0398567361089761 268 28 3 0.107142857142857 0.0111940298507463
GO:BP GO:0043484 regulation of RNA splicing 0.0402398224792871 160 47 3 0.0638297872340425 0.01875
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0404660449290002 2541 36 11 0.305555555555556 0.00432900432900433
GO:BP GO:0051169 nuclear transport 0.0408040028838969 357 41 4 0.0975609756097561 0.0112044817927171
GO:BP GO:0031497 chromatin assembly 0.0439662756570533 194 41 3 0.0731707317073171 0.0154639175257732
GO:BP GO:0009893 positive regulation of metabolic process 0.0456286915330696 3783 36 14 0.388888888888889 0.00370076658736453
GO:BP GO:0009894 regulation of catabolic process 0.0456286915330696 1033 24 5 0.208333333333333 0.00484027105517909
GO:BP GO:0051247 positive regulation of protein metabolic process 0.0456286915330696 1564 36 8 0.222222222222222 0.0051150895140665
GO:BP GO:0051338 regulation of transferase activity 0.0456286915330696 1035 24 5 0.208333333333333 0.00483091787439614
GO:BP GO:0006913 nucleocytoplasmic transport 0.0476329045437146 354 24 3 0.125 0.00847457627118644
GO:BP GO:0032543 mitochondrial translation 0.0485906985884512 136 62 3 0.0483870967741935 0.0220588235294118
GO:CC GO:1990904 ribonucleoprotein complex 4.21649215741758e-19 688 51 24 0.470588235294118 0.0348837209302326
GO:CC GO:0005840 ribosome 4.70350603354183e-19 245 37 16 0.432432432432432 0.0653061224489796
GO:CC GO:0022626 cytosolic ribosome 5.29888106648837e-19 109 26 12 0.461538461538462 0.110091743119266
GO:CC GO:0044391 ribosomal subunit 1.99511329522624e-17 190 37 14 0.378378378378378 0.0736842105263158
GO:CC GO:0022625 cytosolic large ribosomal subunit 4.3218161373076e-16 57 37 10 0.27027027027027 0.175438596491228
GO:CC GO:0015934 large ribosomal subunit 1.05592361209044e-14 118 37 11 0.297297297297297 0.0932203389830508
GO:CC GO:0032991 protein-containing complex 3.07950476447508e-10 5548 37 31 0.837837837837838 0.00558759913482336
GO:CC GO:0005925 focal adhesion 5.75406628445985e-10 420 47 13 0.276595744680851 0.030952380952381
GO:CC GO:0030055 cell-substrate junction 6.28547225789105e-10 427 47 13 0.276595744680851 0.0304449648711944
GO:CC GO:0070062 extracellular exosome 5.11984120134963e-08 2176 40 20 0.5 0.00919117647058824
GO:CC GO:0005829 cytosol 5.45705434959042e-08 5303 41 30 0.731707317073171 0.00565717518385819
GO:CC GO:0043230 extracellular organelle 7.84929253682968e-08 2263 40 20 0.5 0.00883782589482987
GO:CC GO:1903561 extracellular vesicle 7.84929253682968e-08 2261 40 20 0.5 0.00884564352056612
GO:CC GO:0005844 polysome 7.63057986470262e-07 72 26 5 0.192307692307692 0.0694444444444444
GO:CC GO:0070161 anchoring junction 1.27434627321534e-06 836 47 13 0.276595744680851 0.0155502392344498
GO:CC GO:0042788 polysomal ribosome 1.97290896064242e-06 34 26 4 0.153846153846154 0.117647058823529
GO:CC GO:0005634 nucleus 6.424942861581e-06 7592 63 45 0.714285714285714 0.005927291886196
GO:CC GO:0005737 cytoplasm 1.06704620533066e-05 11911 37 36 0.972972972972973 0.00302241625388297
GO:CC GO:0043228 non-membrane-bounded organelle 1.29924743098633e-05 5346 44 28 0.636363636363636 0.00523756079311635
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 1.29924743098633e-05 5338 44 28 0.636363636363636 0.00524541026601723
GO:CC GO:0033290 eukaryotic 48S preinitiation complex 2.83462060905107e-05 15 34 3 0.0882352941176471 0.2
GO:CC GO:0005852 eukaryotic translation initiation factor 3 complex 3.54981999151736e-05 17 34 3 0.0882352941176471 0.176470588235294
GO:CC GO:0016282 eukaryotic 43S preinitiation complex 3.54981999151736e-05 17 34 3 0.0882352941176471 0.176470588235294
GO:CC GO:0070993 translation preinitiation complex 4.09092543743201e-05 18 34 3 0.0882352941176471 0.166666666666667
GO:CC GO:0015935 small ribosomal subunit 4.6411459891764e-05 75 63 5 0.0793650793650794 0.0666666666666667
GO:CC GO:0005615 extracellular space 8.28444597364743e-05 3594 40 20 0.5 0.00556483027267668
GO:CC GO:0031982 vesicle 0.000128073778016365 4055 40 21 0.525 0.00517879161528977
GO:CC GO:0005730 nucleolus 0.000137569341211456 955 47 11 0.234042553191489 0.0115183246073298
GO:CC GO:0030054 cell junction 0.000139656125496567 2105 41 15 0.365853658536585 0.00712589073634204
GO:CC GO:0022627 cytosolic small ribosomal subunit 0.000139656125496567 47 63 4 0.0634920634920635 0.0851063829787234
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.000292795786049266 11296 58 49 0.844827586206897 0.00433781869688385
GO:CC GO:0005622 intracellular anatomical structure 0.000469392791749779 14790 59 57 0.966101694915254 0.00385395537525355
GO:CC GO:0043233 organelle lumen 0.000610528292637481 5565 48 27 0.5625 0.00485175202156334
GO:CC GO:0031974 membrane-enclosed lumen 0.000610528292637481 5565 48 27 0.5625 0.00485175202156334
GO:CC GO:0031981 nuclear lumen 0.00118244624657282 4444 48 23 0.479166666666667 0.00517551755175518
GO:CC GO:1904813 ficolin-1-rich granule lumen 0.00161595576836981 124 47 4 0.0851063829787234 0.032258064516129
GO:CC GO:0005576 extracellular region 0.00210859506725521 4567 40 20 0.5 0.00437924239106635
GO:CC GO:0043227 membrane-bounded organelle 0.00222215971350234 12858 58 51 0.879310344827586 0.00396640223985068
GO:CC GO:0070013 intracellular organelle lumen 0.00238305896062365 5402 63 31 0.492063492063492 0.00573861532765642
GO:CC GO:0043229 intracellular organelle 0.00246714218996423 12491 58 50 0.862068965517241 0.00400288207509407
GO:CC GO:0031966 mitochondrial membrane 0.00377530612500215 746 62 9 0.145161290322581 0.0120643431635389
GO:CC GO:0005740 mitochondrial envelope 0.00565207657848928 797 62 9 0.145161290322581 0.0112923462986198
GO:CC GO:0045202 synapse 0.00565207657848928 1349 24 7 0.291666666666667 0.00518902891030393
GO:CC GO:0101002 ficolin-1-rich granule 0.00568542459324871 184 47 4 0.0851063829787234 0.0217391304347826
GO:CC GO:0005743 mitochondrial inner membrane 0.00623206513916159 503 62 7 0.112903225806452 0.0139165009940358
GO:CC GO:0005681 spliceosomal complex 0.00851468996155423 191 51 4 0.0784313725490196 0.0209424083769634
GO:CC GO:0099572 postsynaptic specialization 0.00905089086418723 358 47 5 0.106382978723404 0.0139664804469274
GO:CC GO:0036464 cytoplasmic ribonucleoprotein granule 0.0103256061952862 237 21 3 0.142857142857143 0.0126582278481013
GO:CC GO:0019866 organelle inner membrane 0.0110619225667759 564 62 7 0.112903225806452 0.0124113475177305
GO:CC GO:0035770 ribonucleoprotein granule 0.0113184433575772 248 21 3 0.142857142857143 0.0120967741935484
GO:CC GO:0005739 mitochondrion 0.011496047053018 1673 62 13 0.209677419354839 0.00777047220561865
GO:CC GO:0043226 organelle 0.011496047053018 14008 58 52 0.896551724137931 0.00371216447744146
GO:CC GO:0014069 postsynaptic density 0.0135200296298551 334 35 4 0.114285714285714 0.0119760479041916
GO:CC GO:0032279 asymmetric synapse 0.0141733630585056 340 35 4 0.114285714285714 0.0117647058823529
GO:CC GO:0005654 nucleoplasm 0.0149018861679518 4102 48 19 0.395833333333333 0.00463188688444661
GO:CC GO:0098984 neuron to neuron synapse 0.0175579669862829 366 35 4 0.114285714285714 0.0109289617486339
GO:CC GO:0098794 postsynapse 0.0183991454422014 639 47 6 0.127659574468085 0.00938967136150235
GO:CC GO:0031975 envelope 0.0236961604500507 1237 62 10 0.161290322580645 0.00808407437348424
GO:CC GO:0031967 organelle envelope 0.0236961604500507 1237 62 10 0.161290322580645 0.00808407437348424
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.0278571537760498 324 47 4 0.0851063829787234 0.0123456790123457
GO:CC GO:0034774 secretory granule lumen 0.0278571537760498 320 47 4 0.0851063829787234 0.0125
GO:CC GO:0031983 vesicle lumen 0.0278571537760498 326 47 4 0.0851063829787234 0.0122699386503067
GO:CC GO:0016020 membrane 0.0278571537760498 9838 26 20 0.769230769230769 0.0020329335230738
GO:CC GO:0005783 endoplasmic reticulum 0.0309293756129912 1982 5 3 0.6 0.00151362260343088
GO:CC GO:0012505 endomembrane system 0.0422289025990698 4640 5 4 0.8 0.000862068965517241
GO:CC GO:0140513 nuclear protein-containing complex 0.0476550957064965 1249 51 8 0.156862745098039 0.00640512409927942
GO:MF GO:0003723 RNA binding 1.32836965269901e-19 1943 37 29 0.783783783783784 0.0149253731343284
GO:MF GO:0003735 structural constituent of ribosome 2.85691062363363e-14 171 26 11 0.423076923076923 0.064327485380117
GO:MF GO:0003676 nucleic acid binding 3.41485084747312e-12 4276 24 23 0.958333333333333 0.00537885874649205
GO:MF GO:0008135 translation factor activity, RNA binding 8.46956461532518e-11 99 63 10 0.158730158730159 0.101010101010101
GO:MF GO:0090079 translation regulator activity, nucleic acid binding 6.13105073482105e-10 123 63 10 0.158730158730159 0.0813008130081301
GO:MF GO:0045182 translation regulator activity 5.14015963218873e-09 155 63 10 0.158730158730159 0.0645161290322581
GO:MF GO:0019843 rRNA binding 6.4337521819483e-09 63 24 6 0.25 0.0952380952380952
GO:MF GO:1901363 heterocyclic compound binding 6.4861134339677e-09 6228 24 23 0.958333333333333 0.00369299935773924
GO:MF GO:0097159 organic cyclic compound binding 7.71741830048299e-09 6309 24 23 0.958333333333333 0.00364558567126327
GO:MF GO:0043021 ribonucleoprotein complex binding 2.09344099132158e-08 137 62 9 0.145161290322581 0.0656934306569343
GO:MF GO:0005198 structural molecule activity 2.35151747827742e-08 698 26 11 0.423076923076923 0.0157593123209169
GO:MF GO:0008097 5S rRNA binding 1.34603220047301e-07 11 7 3 0.428571428571429 0.272727272727273
GO:MF GO:0043022 ribosome binding 8.91134781559953e-07 59 62 6 0.0967741935483871 0.101694915254237
GO:MF GO:0003743 translation initiation factor activity 8.91134781559953e-07 58 63 6 0.0952380952380952 0.103448275862069
GO:MF GO:0003746 translation elongation factor activity 1.96685440912762e-05 27 14 3 0.214285714285714 0.111111111111111
GO:MF GO:0045296 cadherin binding 8.55709838947537e-05 333 54 8 0.148148148148148 0.024024024024024
GO:MF GO:0050839 cell adhesion molecule binding 0.000348083193448015 546 54 9 0.166666666666667 0.0164835164835165
GO:MF GO:0000049 tRNA binding 0.00102578572710773 69 62 4 0.0645161290322581 0.0579710144927536
GO:MF GO:0005515 protein binding 0.00343773687573762 14767 44 43 0.977272727272727 0.00291189815128327
GO:MF GO:0031625 ubiquitin protein ligase binding 0.00670470324701988 296 47 5 0.106382978723404 0.0168918918918919
GO:MF GO:0044389 ubiquitin-like protein ligase binding 0.0081025260132201 314 47 5 0.106382978723404 0.0159235668789809
GO:MF GO:0004857 enzyme inhibitor activity 0.00920531884446931 385 24 4 0.166666666666667 0.0103896103896104
GO:MF GO:0044877 protein-containing complex binding 0.0107571005109135 1287 66 12 0.181818181818182 0.00932400932400932
GO:MF GO:0019899 enzyme binding 0.0139222534483709 2074 28 9 0.321428571428571 0.00433944069431051
GO:MF GO:0051082 unfolded protein binding 0.0144781865317966 112 47 3 0.0638297872340425 0.0267857142857143
GO:MF GO:0022853 active ion transmembrane transporter activity 0.0144781865317966 213 25 3 0.12 0.0140845070422535
GO:MF GO:0019901 protein kinase binding 0.0146916980685726 673 28 5 0.178571428571429 0.00742942050520059
GO:MF GO:0003713 transcription coactivator activity 0.0153268961055479 280 41 4 0.0975609756097561 0.0142857142857143
GO:MF GO:0015291 secondary active transmembrane transporter activity 0.0157243333848365 237 25 3 0.12 0.0126582278481013
GO:MF GO:0003712 transcription coregulator activity 0.0182789613768619 506 41 5 0.121951219512195 0.00988142292490119
GO:MF GO:0019900 kinase binding 0.0182789613768619 752 28 5 0.178571428571429 0.00664893617021277
GO:MF GO:0030234 enzyme regulator activity 0.0187839444281522 1248 6 3 0.5 0.00240384615384615
GO:MF GO:0005525 GTP binding 0.0187839444281522 381 55 5 0.0909090909090909 0.0131233595800525
GO:MF GO:0032550 purine ribonucleoside binding 0.0191515498188508 386 55 5 0.0909090909090909 0.0129533678756477
GO:MF GO:0001883 purine nucleoside binding 0.019335281043288 389 55 5 0.0909090909090909 0.012853470437018
GO:MF GO:0032549 ribonucleoside binding 0.019335281043288 389 55 5 0.0909090909090909 0.012853470437018
GO:MF GO:0001882 nucleoside binding 0.0201214956561456 395 55 5 0.0909090909090909 0.0126582278481013
GO:MF GO:0019001 guanyl nucleotide binding 0.0209769086429566 403 55 5 0.0909090909090909 0.0124069478908189
GO:MF GO:0032561 guanyl ribonucleotide binding 0.0209769086429566 403 55 5 0.0909090909090909 0.0124069478908189
GO:MF GO:0022804 active transmembrane transporter activity 0.0248406055117198 312 25 3 0.12 0.00961538461538462
GO:MF GO:0003682 chromatin binding 0.0294656537320447 571 43 5 0.116279069767442 0.00875656742556918
GO:MF GO:0019887 protein kinase regulator activity 0.0355616182346618 191 48 3 0.0625 0.0157068062827225
GO:MF GO:0098772 molecular function regulator 0.0391990567119223 2363 32 9 0.28125 0.003808717731697
GO:MF GO:0003924 GTPase activity 0.0428555629621123 328 31 3 0.0967741935483871 0.00914634146341463
GO:MF GO:0019207 kinase regulator activity 0.0476658026126828 221 48 3 0.0625 0.0135746606334842
HPA HPA:0190223 esophagus; squamous epithelial cells[High] 0.000202424956676629 1596 26 15 0.576923076923077 0.0093984962406015
HPA HPA:0600432 tonsil; germinal center cells[≥Medium] 0.000236399351588893 3988 56 38 0.678571428571429 0.00952858575727182
HPA HPA:0330223 oral mucosa; squamous epithelial cells[High] 0.000236399351588893 1112 43 16 0.372093023255814 0.0143884892086331
HPA HPA:0470683 skin 2; epidermal cells[High] 0.000236399351588893 1346 26 13 0.5 0.00965824665676077
HPA HPA:0620223 vagina; squamous epithelial cells[High] 0.000236399351588893 1091 30 13 0.433333333333333 0.0119156736938588
HPA HPA:0600433 tonsil; germinal center cells[High] 0.000236399351588893 1179 33 14 0.424242424242424 0.0118744698897371
HPA HPA:0350473 pancreas; exocrine glandular cells[High] 0.000246127859332699 1879 26 15 0.576923076923077 0.00798296966471527
HPA HPA:0170053 endometrium 2; glandular cells[High] 0.000253140109172249 1282 24 12 0.5 0.0093603744149766
HPA HPA:0550053 stomach 2; glandular cells[High] 0.000284446091249169 2350 30 18 0.6 0.00765957446808511
HPA HPA:0600223 tonsil; squamous epithelial cells[High] 0.000383891651928449 1442 30 14 0.466666666666667 0.00970873786407767
HPA HPA:0090163 cerebellum; Purkinje cells[High] 0.000532135449001904 1527 26 13 0.5 0.00851342501637197
HPA HPA:0400053 rectum; glandular cells[High] 0.000876004901865809 2687 20 14 0.7 0.0052102716784518
HPA HPA:0540053 stomach 1; glandular cells[High] 0.000876004901865809 2365 27 16 0.592592592592593 0.00676532769556025
HPA HPA:0480053 small intestine; glandular cells[High] 0.00106231968015924 2723 27 17 0.62962962962963 0.00624311421226588
HPA HPA:0460663 skin 1; keratinocytes[High] 0.0014582424873483 848 30 10 0.333333333333333 0.0117924528301887
HPA HPA:0600222 tonsil; squamous epithelial cells[≥Medium] 0.0014582424873483 4851 56 40 0.714285714285714 0.00824572253143682
HPA HPA:0110222 cervix, uterine; squamous epithelial cells[≥Medium] 0.00177330116075777 3617 43 27 0.627906976744186 0.00746474979264584
HPA HPA:0030053 appendix; glandular cells[High] 0.00177330116075777 1986 33 16 0.484848484848485 0.0080563947633434
HPA HPA:0350472 pancreas; exocrine glandular cells[≥Medium] 0.00208199934748763 5157 56 41 0.732142857142857 0.00795035873569905
HPA HPA:0600442 tonsil; non-germinal center cells[≥Medium] 0.00231854224920671 4079 36 25 0.694444444444444 0.00612895317479774
HPA HPA:0210053 fallopian tube; glandular cells[High] 0.00267129434778213 1728 28 13 0.464285714285714 0.00752314814814815
HPA HPA:0110223 cervix, uterine; squamous epithelial cells[High] 0.00267129434778213 986 24 9 0.375 0.00912778904665314
HPA HPA:0100133 cerebral cortex; neuronal cells[High] 0.00267129434778213 1785 24 12 0.5 0.00672268907563025
HPA HPA:0460641 skin 1; Langerhans[≥Low] 0.00326059015228957 4634 37 27 0.72972972972973 0.00582649978420371
HPA HPA:0430053 seminal vesicle; glandular cells[High] 0.00326059015228957 1410 43 15 0.348837209302326 0.0106382978723404
HPA HPA:0420053 salivary gland; glandular cells[High] 0.00326059015228957 1418 22 10 0.454545454545455 0.00705218617771509
HPA HPA:0150053 duodenum; glandular cells[High] 0.00330253210355527 2767 56 27 0.482142857142857 0.00975786049873509
HPA HPA:0050053 breast; glandular cells[High] 0.00341601710000088 1299 24 10 0.416666666666667 0.00769822940723634
HPA HPA:0030052 appendix; glandular cells[≥Medium] 0.00375355019916589 5767 56 43 0.767857142857143 0.00745621640367609
HPA HPA:0050052 breast; glandular cells[≥Medium] 0.00398873283865166 4971 56 39 0.696428571428571 0.00784550392275196
HPA HPA:0351182 pancreas; pancreatic endocrine cells[≥Medium] 0.00398873283865166 3523 21 15 0.714285714285714 0.00425773488504116
HPA HPA:0460662 skin 1; keratinocytes[≥Medium] 0.00480129037417287 3893 56 33 0.589285714285714 0.00847675314667352
HPA HPA:0600431 tonsil; germinal center cells[≥Low] 0.00480129037417287 5845 56 43 0.767857142857143 0.00735671514114628
HPA HPA:0310431 lymph node; germinal center cells[≥Low] 0.00480129037417287 4935 55 38 0.690909090909091 0.00770010131712259
HPA HPA:0030072 appendix; lymphoid tissue[≥Medium] 0.00482508317980073 3131 52 27 0.519230769230769 0.00862344298946024
HPA HPA:0530721 spleen; cells in white pulp[≥Low] 0.0049273563639034 4249 35 24 0.685714285714286 0.00564838785596611
HPA HPA:0170252 endometrium 2; cells in endometrial stroma[≥Medium] 0.0059476468013526 1722 55 19 0.345454545454545 0.0110336817653891
HPA HPA:0460651 skin 1; fibroblasts[≥Low] 0.00675065660721957 4726 56 37 0.660714285714286 0.00782903089293271
HPA HPA:0420052 salivary gland; glandular cells[≥Medium] 0.00695720447137202 4742 56 37 0.660714285714286 0.00780261493040911
HPA HPA:0190222 esophagus; squamous epithelial cells[≥Medium] 0.00695720447137202 4937 56 38 0.678571428571429 0.00769698197285801
HPA HPA:0310432 lymph node; germinal center cells[≥Medium] 0.00761527160549429 3209 55 28 0.509090909090909 0.00872545964474914
HPA HPA:0330222 oral mucosa; squamous epithelial cells[≥Medium] 0.00810024833531066 4254 36 24 0.666666666666667 0.00564174894217207
HPA HPA:0170251 endometrium 2; cells in endometrial stroma[≥Low] 0.00838344877892408 3410 55 29 0.527272727272727 0.00850439882697947
HPA HPA:0110221 cervix, uterine; squamous epithelial cells[≥Low] 0.00854236296926989 5325 37 28 0.756756756756757 0.00525821596244131
HPA HPA:0460672 skin 1; melanocytes[≥Medium] 0.00854236296926989 3700 56 31 0.553571428571429 0.00837837837837838
HPA HPA:0170052 endometrium 2; glandular cells[≥Medium] 0.00854236296926989 4758 35 25 0.714285714285714 0.00525430853299706
HPA HPA:0250132 hippocampus; neuronal cells[≥Medium] 0.00907591347328074 4126 22 16 0.727272727272727 0.00387784779447407
HPA HPA:0310433 lymph node; germinal center cells[High] 0.00979670992669844 908 33 9 0.272727272727273 0.00991189427312775
HPA HPA:0060103 bronchus; respiratory epithelial cells[High] 0.00979670992669844 1890 24 11 0.458333333333333 0.00582010582010582
HPA HPA:0430052 seminal vesicle; glandular cells[≥Medium] 0.0115164615040669 5096 56 38 0.678571428571429 0.00745682888540031
HPA HPA:0160251 endometrium 1; cells in endometrial stroma[≥Low] 0.0115164615040669 3962 35 22 0.628571428571429 0.00555275113579
HPA HPA:0090191 cerebellum; cells in molecular layer[≥Low] 0.0115562963240147 4336 54 33 0.611111111111111 0.00761070110701107
HPA HPA:0460643 skin 1; Langerhans[High] 0.0119791918574142 734 20 6 0.3 0.00817438692098093
HPA HPA:0470682 skin 2; epidermal cells[≥Medium] 0.012299305607303 4735 56 36 0.642857142857143 0.00760295670538543
HPA HPA:0460642 skin 1; Langerhans[≥Medium] 0.0125967471193217 3123 43 22 0.511627906976744 0.00704450848543068
HPA HPA:0610833 urinary bladder; urothelial cells[High] 0.0126298617437821 1969 21 10 0.476190476190476 0.00507872016251905
HPA HPA:0610832 urinary bladder; urothelial cells[≥Medium] 0.0126298617437821 5819 37 29 0.783783783783784 0.00498367417081973
HPA HPA:0530722 spleen; cells in white pulp[≥Medium] 0.0126298617437821 2645 56 24 0.428571428571429 0.00907372400756144
HPA HPA:0030073 appendix; lymphoid tissue[High] 0.0126298617437821 803 32 8 0.25 0.0099626400996264
HPA HPA:0020053 adrenal gland; glandular cells[High] 0.0126298617437821 2199 22 11 0.5 0.00500227376080036
HPA HPA:0090192 cerebellum; cells in molecular layer[≥Medium] 0.0126298617437821 2699 49 22 0.448979591836735 0.00815116709892553
HPA HPA:0090162 cerebellum; Purkinje cells[≥Medium] 0.0126879949664108 4047 27 18 0.666666666666667 0.0044477390659748
HPA HPA:0460671 skin 1; melanocytes[≥Low] 0.0128141756950595 5378 41 30 0.731707317073171 0.00557828188917813
HPA HPA:0160053 endometrium 1; glandular cells[High] 0.0137893858683441 1413 24 9 0.375 0.00636942675159236
HPA HPA:0510653 soft tissue 2; fibroblasts[High] 0.0142915992419668 481 22 5 0.227272727272727 0.0103950103950104
HPA HPA:0100132 cerebral cortex; neuronal cells[≥Medium] 0.0147384240135323 4883 41 28 0.682926829268293 0.00573417980749539
HPA HPA:0080131 caudate; neuronal cells[≥Low] 0.0159584420033224 6042 35 28 0.8 0.00463422707712678
HPA HPA:0530723 spleen; cells in white pulp[High] 0.0163853512816892 811 41 9 0.219512195121951 0.0110974106041924
HPA HPA:0250131 hippocampus; neuronal cells[≥Low] 0.0185720946793164 6101 35 28 0.8 0.00458941157187346
HPA HPA:0250133 hippocampus; neuronal cells[High] 0.0185720946793164 1210 24 8 0.333333333333333 0.00661157024793388
HPA HPA:0460673 skin 1; melanocytes[High] 0.0185720946793164 848 20 6 0.3 0.00707547169811321
HPA HPA:0310443 lymph node; non-germinal center cells[High] 0.0185720946793164 1169 41 11 0.268292682926829 0.00940975192472198
HPA HPA:0500652 soft tissue 1; fibroblasts[≥Medium] 0.0193131375629559 2649 52 22 0.423076923076923 0.00830502076255191
HPA HPA:0320103 nasopharynx; respiratory epithelial cells[High] 0.0193131375629559 1844 43 15 0.348837209302326 0.00813449023861171
HPA HPA:0510703 soft tissue 2; peripheral nerve[High] 0.0193131375629559 263 43 5 0.116279069767442 0.0190114068441065
HPA HPA:0300412 lung; macrophages[≥Medium] 0.0193819388053267 4732 41 27 0.658536585365854 0.00570583262890955
HPA HPA:0620222 vagina; squamous epithelial cells[≥Medium] 0.020185512764103 3945 50 28 0.56 0.00709759188846641
HPA HPA:0400052 rectum; glandular cells[≥Medium] 0.0252306866979452 6410 56 43 0.767857142857143 0.00670826833073323
HPA HPA:0540052 stomach 1; glandular cells[≥Medium] 0.0252306866979452 6201 56 42 0.75 0.00677310111272375
HPA HPA:0510651 soft tissue 2; fibroblasts[≥Low] 0.0270655723591048 4037 35 21 0.6 0.00520188258607877
HPA HPA:0160252 endometrium 1; cells in endometrial stroma[≥Medium] 0.027619947689863 2142 22 10 0.454545454545455 0.00466853408029879
HPA HPA:0480052 small intestine; glandular cells[≥Medium] 0.0293711425380898 6461 56 43 0.767857142857143 0.00665531651447144
HPA HPA:0340000 ovary 0.0296008787722398 5298 35 25 0.714285714285714 0.00471876179690449
HPA HPA:0600443 tonsil; non-germinal center cells[High] 0.0297795138627727 1271 41 11 0.268292682926829 0.00865460267505901
HPA HPA:0030071 appendix; lymphoid tissue[≥Low] 0.0298836461979254 4976 55 35 0.636363636363636 0.00703376205787781
HPA HPA:0590052 thyroid gland; glandular cells[≥Medium] 0.0298836461979254 5454 56 38 0.678571428571429 0.00696736340300697
HPA HPA:0330000 oral mucosa 0.0298836461979254 6102 33 26 0.787878787878788 0.0042608980662078
HPA HPA:0330221 oral mucosa; squamous epithelial cells[≥Low] 0.0298836461979254 6102 33 26 0.787878787878788 0.0042608980662078
HPA HPA:0050093 breast; myoepithelial cells[High] 0.0298836461979254 798 24 6 0.25 0.0075187969924812
HPA HPA:0320102 nasopharynx; respiratory epithelial cells[≥Medium] 0.0298850795893054 5010 35 24 0.685714285714286 0.00479041916167665
HPA HPA:0040081 bone marrow; hematopoietic cells[≥Low] 0.0302091849831854 6349 35 28 0.8 0.00441014332965821
HPA HPA:0040000 bone marrow 0.0302091849831854 6349 35 28 0.8 0.00441014332965821
HPA HPA:0210052 fallopian tube; glandular cells[≥Medium] 0.0302091849831854 5023 35 24 0.685714285714286 0.00477802110292654
HPA HPA:0600221 tonsil; squamous epithelial cells[≥Low] 0.0319125906645738 6518 56 43 0.767857142857143 0.00659711567965634
HPA HPA:0460661 skin 1; keratinocytes[≥Low] 0.0323633433682951 6051 41 31 0.75609756097561 0.00512312014543051
HPA HPA:0050092 breast; myoepithelial cells[≥Medium] 0.0323633433682951 3700 34 19 0.558823529411765 0.00513513513513513
HPA HPA:0500651 soft tissue 1; fibroblasts[≥Low] 0.0331872428516271 4156 54 30 0.555555555555556 0.00721847930702599
HPA HPA:0550052 stomach 2; glandular cells[≥Medium] 0.0340522044025287 6134 56 41 0.732142857142857 0.00668405608086078
HPA HPA:0600441 tonsil; non-germinal center cells[≥Low] 0.0340522044025287 5966 37 28 0.756756756756757 0.00469326181696279
HPA HPA:0160051 endometrium 1; glandular cells[≥Low] 0.0340522044025287 6663 41 33 0.804878048780488 0.00495272399819901
HPA HPA:0210051 fallopian tube; glandular cells[≥Low] 0.0340522044025287 6089 41 31 0.75609756097561 0.00509114797175234
HPA HPA:0310000 lymph node 0.0340522044025287 6374 41 32 0.780487804878049 0.0050203953561343
HPA HPA:0340461 ovary; ovarian stroma cells[≥Low] 0.0340522044025287 3894 35 20 0.571428571428571 0.00513610683102209
HPA HPA:0360052 parathyroid gland; glandular cells[≥Medium] 0.0341896933365298 4306 15 11 0.733333333333333 0.0025545750116117
HPA HPA:0530000 spleen 0.0343820452966704 5756 35 26 0.742857142857143 0.00451702571230021
HPA HPA:0290402 liver; hepatocytes[≥Medium] 0.0343820452966704 3640 15 10 0.666666666666667 0.00274725274725275
HPA HPA:0090161 cerebellum; Purkinje cells[≥Low] 0.0357124999152726 5460 22 17 0.772727272727273 0.00311355311355311
HPA HPA:0380513 placenta; decidual cells[High] 0.0357124999152726 1144 5 3 0.6 0.00262237762237762
HPA HPA:0301171 lung; alveolar cells[≥Low] 0.0367954454094737 5028 41 27 0.658536585365854 0.00536992840095465
HPA HPA:0380521 placenta; trophoblastic cells[≥Low] 0.0369773328585174 6388 56 42 0.75 0.00657482780212899
HPA HPA:0340451 ovary; follicle cells[≥Low] 0.0375072234113381 3228 34 17 0.5 0.00526641883519207
HPA HPA:0620000 vagina 0.0375072234113381 5868 41 30 0.731707317073171 0.00511247443762781
HPA HPA:0620221 vagina; squamous epithelial cells[≥Low] 0.0375072234113381 5868 41 30 0.731707317073171 0.00511247443762781
HPA HPA:0360053 parathyroid gland; glandular cells[High] 0.0375072234113381 1486 11 5 0.454545454545455 0.00336473755047106
HPA HPA:0351181 pancreas; pancreatic endocrine cells[≥Low] 0.038549864039056 5497 35 25 0.714285714285714 0.00454793523740222
HPA HPA:0290401 liver; hepatocytes[≥Low] 0.0387266281482564 5611 41 29 0.707317073170732 0.00516841917661736
HPA HPA:0160052 endometrium 1; glandular cells[≥Medium] 0.0387266281482564 5014 56 35 0.625 0.00698045472676506
HPA HPA:0500112 soft tissue 1; chondrocytes[≥Medium] 0.0387266281482564 1395 16 6 0.375 0.0043010752688172
HPA HPA:0380523 placenta; trophoblastic cells[High] 0.0387543174884768 1998 33 12 0.363636363636364 0.00600600600600601
HPA HPA:0080132 caudate; neuronal cells[≥Medium] 0.0401810765886045 4022 37 21 0.567567567567568 0.00522128294380905
HPA HPA:0130053 colon; glandular cells[High] 0.0401810765886045 2538 33 14 0.424242424242424 0.00551615445232467
HPA HPA:0291161 liver; cholangiocytes[≥Low] 0.0427757501814904 3867 34 19 0.558823529411765 0.00491336953710887
HPA HPA:0100131 cerebral cortex; neuronal cells[≥Low] 0.0427757501814904 6566 35 28 0.8 0.00426439232409382
HPA HPA:0380522 placenta; trophoblastic cells[≥Medium] 0.045347759612797 5074 56 35 0.625 0.00689791091840757
HPA HPA:0150052 duodenum; glandular cells[≥Medium] 0.045347759612797 6480 56 42 0.75 0.00648148148148148
HPA HPA:0570743 testis; cells in seminiferous ducts[High] 0.0454336420190615 822 35 7 0.2 0.00851581508515815
KEGG KEGG:03010 Ribosome 3.05196140493928e-11 153 26 11 0.423076923076923 0.0718954248366013
KEGG KEGG:05171 Coronavirus disease - COVID-19 1.40292389209181e-09 231 26 11 0.423076923076923 0.0476190476190476
KEGG KEGG:03013 RNA transport 0.0172678066346851 180 34 5 0.147058823529412 0.0277777777777778
MIRNA MIRNA:hsa-miR-16-5p hsa-miR-16-5p 1.46879478413139e-07 1556 19 14 0.736842105263158 0.0089974293059126
MIRNA MIRNA:hsa-miR-149-5p hsa-miR-149-5p 1.69191870110719e-05 394 47 11 0.234042553191489 0.0279187817258883
MIRNA MIRNA:hsa-miR-615-3p hsa-miR-615-3p 4.98510672027813e-05 891 50 15 0.3 0.0168350168350168
MIRNA MIRNA:hsa-miR-877-5p hsa-miR-877-5p 0.000173058354762348 233 47 8 0.170212765957447 0.0343347639484979
MIRNA MIRNA:hsa-miR-324-3p hsa-miR-324-3p 0.000204491249278428 336 47 9 0.191489361702128 0.0267857142857143
MIRNA MIRNA:hsa-miR-186-5p hsa-miR-186-5p 0.00022668550951229 749 9 6 0.666666666666667 0.00801068090787717
MIRNA MIRNA:hsa-miR-423-3p hsa-miR-423-3p 0.000866702248056689 229 18 5 0.277777777777778 0.0218340611353712
MIRNA MIRNA:hsa-miR-1260b hsa-miR-1260b 0.000866702248056689 270 26 6 0.230769230769231 0.0222222222222222
MIRNA MIRNA:hsa-miR-296-3p hsa-miR-296-3p 0.00155727923545927 255 46 7 0.152173913043478 0.0274509803921569
MIRNA MIRNA:hsa-let-7b-5p hsa-let-7b-5p 0.00263130553815462 1212 55 15 0.272727272727273 0.0123762376237624
MIRNA MIRNA:hsa-miR-100-5p hsa-miR-100-5p 0.00291822215136739 250 53 7 0.132075471698113 0.028
MIRNA MIRNA:hsa-miR-92a-3p hsa-miR-92a-3p 0.00454556326157119 1404 35 12 0.342857142857143 0.00854700854700855
MIRNA MIRNA:hsa-miR-744-5p hsa-miR-744-5p 0.00454556326157119 435 46 8 0.173913043478261 0.0183908045977011
MIRNA MIRNA:hsa-miR-25-3p hsa-miR-25-3p 0.0105241041943109 515 24 6 0.25 0.0116504854368932
MIRNA MIRNA:hsa-miR-1229-3p hsa-miR-1229-3p 0.0150128955452602 207 9 3 0.333333333333333 0.0144927536231884
MIRNA MIRNA:hsa-miR-320a hsa-miR-320a 0.0226704882597962 584 35 7 0.2 0.011986301369863
MIRNA MIRNA:hsa-miR-4733-5p hsa-miR-4733-5p 0.0226704882597962 82 62 4 0.0645161290322581 0.0487804878048781
MIRNA MIRNA:hsa-miR-652-3p hsa-miR-652-3p 0.0241964344218664 162 14 3 0.214285714285714 0.0185185185185185
MIRNA MIRNA:hsa-miR-484 hsa-miR-484 0.02466440634652 890 18 6 0.333333333333333 0.00674157303370787
MIRNA MIRNA:hsa-miR-4794 hsa-miR-4794 0.026743455143681 132 43 4 0.0930232558139535 0.0303030303030303
MIRNA MIRNA:hsa-miR-664a-5p hsa-miR-664a-5p 0.026743455143681 132 43 4 0.0930232558139535 0.0303030303030303
MIRNA MIRNA:hsa-miR-10a-5p hsa-miR-10a-5p 0.0296989728746276 461 48 7 0.145833333333333 0.0151843817787419
MIRNA MIRNA:hsa-miR-92b-3p hsa-miR-92b-3p 0.02995475688814 707 24 6 0.25 0.00848656294200849
MIRNA MIRNA:hsa-let-7a-5p hsa-let-7a-5p 0.030672866314078 637 59 9 0.152542372881356 0.0141287284144427
MIRNA MIRNA:hsa-miR-125b-5p hsa-miR-125b-5p 0.036184874290659 427 41 6 0.146341463414634 0.0140515222482436
MIRNA MIRNA:hsa-miR-769-3p hsa-miR-769-3p 0.0383802152163072 165 19 3 0.157894736842105 0.0181818181818182
MIRNA MIRNA:hsa-miR-22-3p hsa-miR-22-3p 0.0447763216229092 163 21 3 0.142857142857143 0.0184049079754601
MIRNA MIRNA:hsa-miR-4659b-5p hsa-miR-4659b-5p 0.0482463267999601 74 48 3 0.0625 0.0405405405405405
MIRNA MIRNA:hsa-miR-4659a-5p hsa-miR-4659a-5p 0.0482463267999601 74 48 3 0.0625 0.0405405405405405
MIRNA MIRNA:hsa-miR-18a-5p hsa-miR-18a-5p 0.0482463267999601 260 14 3 0.214285714285714 0.0115384615384615
MIRNA MIRNA:hsa-miR-132-3p hsa-miR-132-3p 0.0482463267999601 252 31 4 0.129032258064516 0.0158730158730159
REAC REAC:R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 1.7733885275626e-21 112 34 16 0.470588235294118 0.142857142857143
REAC REAC:R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 1.7733885275626e-21 113 34 16 0.470588235294118 0.141592920353982
REAC REAC:R-HSA-72737 Cap-dependent Translation Initiation 2.42406121025485e-21 120 34 16 0.470588235294118 0.133333333333333
REAC REAC:R-HSA-72613 Eukaryotic Translation Initiation 2.42406121025485e-21 120 34 16 0.470588235294118 0.133333333333333
REAC REAC:R-HSA-156842 Eukaryotic Translation Elongation 2.42406121025485e-21 94 26 14 0.538461538461538 0.148936170212766
REAC REAC:R-HSA-72766 Translation 5.65984283964399e-20 292 34 19 0.558823529411765 0.0650684931506849
REAC REAC:R-HSA-156902 Peptide chain elongation 1.31832453547941e-19 90 26 13 0.5 0.144444444444444
REAC REAC:R-HSA-72689 Formation of a pool of free 40S subunits 6.47475936605583e-19 102 26 13 0.5 0.127450980392157
REAC REAC:R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency 8.70864787086512e-16 102 31 12 0.387096774193548 0.117647058823529
REAC REAC:R-HSA-192823 Viral mRNA Translation 1.21563766328105e-15 90 26 11 0.423076923076923 0.122222222222222
REAC REAC:R-HSA-2408557 Selenocysteine synthesis 1.67229198024893e-15 94 26 11 0.423076923076923 0.117021276595745
REAC REAC:R-HSA-72764 Eukaryotic Translation Termination 1.67229198024893e-15 94 26 11 0.423076923076923 0.117021276595745
REAC REAC:R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 1.966547427086e-15 96 26 11 0.423076923076923 0.114583333333333
REAC REAC:R-HSA-168255 Influenza Infection 5.63975466018508e-15 152 26 12 0.461538461538462 0.0789473684210526
REAC REAC:R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 1.09871399976451e-14 113 26 11 0.423076923076923 0.0973451327433628
REAC REAC:R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 1.30560520741492e-14 116 26 11 0.423076923076923 0.0948275862068965
REAC REAC:R-HSA-927802 Nonsense-Mediated Decay (NMD) 1.30560520741492e-14 116 26 11 0.423076923076923 0.0948275862068965
REAC REAC:R-HSA-2408522 Selenoamino acid metabolism 1.35924021744425e-14 117 26 11 0.423076923076923 0.094017094017094
REAC REAC:R-HSA-168273 Influenza Viral RNA Transcription and Replication 5.48294797976799e-14 133 26 11 0.423076923076923 0.0827067669172932
REAC REAC:R-HSA-9711097 Cellular response to starvation 8.04620713619563e-14 157 31 12 0.387096774193548 0.0764331210191083
REAC REAC:R-HSA-9010553 Regulation of expression of SLITs and ROBOs 8.24554999847589e-13 171 26 11 0.423076923076923 0.064327485380117
REAC REAC:R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 1.66979277993324e-12 183 26 11 0.423076923076923 0.0601092896174863
REAC REAC:R-HSA-8868773 rRNA processing in the nucleus and cytosol 2.87606530016153e-12 193 26 11 0.423076923076923 0.0569948186528497
REAC REAC:R-HSA-72312 rRNA processing 4.81066371642028e-12 203 26 11 0.423076923076923 0.0541871921182266
REAC REAC:R-HSA-376176 Signaling by ROBO receptors 9.61309136636132e-12 217 26 11 0.423076923076923 0.0506912442396313
REAC REAC:R-HSA-5663205 Infectious disease 4.60385197053393e-10 815 26 15 0.576923076923077 0.0184049079754601
REAC REAC:R-HSA-71291 Metabolism of amino acids and derivatives 2.70067759828704e-09 368 26 11 0.423076923076923 0.0298913043478261
REAC REAC:R-HSA-72702 Ribosomal scanning and start codon recognition 3.67221011627289e-09 59 34 7 0.205882352941176 0.11864406779661
REAC REAC:R-HSA-72649 Translation initiation complex formation 3.67221011627289e-09 59 34 7 0.205882352941176 0.11864406779661
REAC REAC:R-HSA-8953854 Metabolism of RNA 3.94595423468382e-09 658 51 18 0.352941176470588 0.027355623100304
REAC REAC:R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 3.94595423468382e-09 60 34 7 0.205882352941176 0.116666666666667
REAC REAC:R-HSA-2262752 Cellular responses to stress 8.53060895751475e-09 546 31 13 0.419354838709677 0.0238095238095238
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 1.12729639948301e-08 560 31 13 0.419354838709677 0.0232142857142857
REAC REAC:R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 7.11827797669564e-08 52 34 6 0.176470588235294 0.115384615384615
REAC REAC:R-HSA-392499 Metabolism of proteins 1.19819474271645e-07 1961 26 18 0.692307692307692 0.00917899031106578
REAC REAC:R-HSA-422475 Axon guidance 1.35785467683945e-07 549 26 11 0.423076923076923 0.0200364298724954
REAC REAC:R-HSA-9675108 Nervous system development 2.0931048062846e-07 574 26 11 0.423076923076923 0.0191637630662021
REAC REAC:R-HSA-1643685 Disease 1.62144051327089e-06 1509 26 15 0.576923076923077 0.0099403578528827
REAC REAC:R-HSA-1266738 Developmental Biology 9.49518937085016e-05 1069 26 11 0.423076923076923 0.010289990645463
REAC REAC:R-HSA-8876725 Protein methylation 0.000246499599079534 17 47 3 0.0638297872340425 0.176470588235294
REAC REAC:R-HSA-176033 Interactions of Vpr with host cellular proteins 0.00127680583626571 34 41 3 0.0731707317073171 0.0882352941176471
REAC REAC:R-HSA-162909 Host Interactions of HIV factors 0.00540493877499916 125 41 4 0.0975609756097561 0.032
REAC REAC:R-HSA-1430728 Metabolism 0.0244032712679332 2070 26 11 0.423076923076923 0.00531400966183575
REAC REAC:R-HSA-162906 HIV Infection 0.0293089710864152 226 20 3 0.15 0.0132743362831858
REAC REAC:R-HSA-72163 mRNA Splicing - Major Pathway 0.0353622368726209 178 51 4 0.0784313725490196 0.0224719101123595
REAC REAC:R-HSA-72172 mRNA Splicing 0.0383139384591128 186 51 4 0.0784313725490196 0.021505376344086
TF TF:M08982 Factor: YY1; motif: NAANATGGCGNNN 0.000701542328715875 7125 25 22 0.88 0.00308771929824561
TF TF:M08982_1 Factor: YY1; motif: NAANATGGCGNNN; match class: 1 0.00139614853154324 1662 12 8 0.666666666666667 0.00481347773766546
TF TF:M00069 Factor: YY1; motif: NNNCGGCCATCTTGNCTSNW 0.00139614853154324 8347 24 22 0.916666666666667 0.00263567748891817
TF TF:M10436 Factor: YY1; motif: CAANATGGCGGC 0.00139614853154324 8220 23 21 0.91304347826087 0.00255474452554745
TF TF:M08231_1 Factor: Elk-1:T-bet; motif: TCACACCGGAAGNN; match class: 1 0.00202666228406497 1581 7 6 0.857142857142857 0.00379506641366224
TF TF:M00425_1 Factor: E2F; motif: TTTCGCGC; match class: 1 0.00261317416737656 5355 27 19 0.703703703703704 0.00354808590102708
TF TF:M12310 Factor: ZNF597; motif: NGCCGCCATTTTGN 0.00261317416737656 437 20 6 0.3 0.0137299771167048
TF TF:M10119 Factor: REX-1; motif: GGCMGCCATTTT 0.00261317416737656 1888 62 19 0.306451612903226 0.0100635593220339
TF TF:M10104 Factor: YY1; motif: CAARATGGCGGC 0.00274435872972695 6071 25 19 0.76 0.00312963267995388
TF TF:M02069_1 Factor: Erm; motif: ACCGGAAGTN; match class: 1 0.00456793911455264 1955 64 19 0.296875 0.00971867007672634
TF TF:M03988_1 Factor: FLI1; motif: ACCGGAARTN; match class: 1 0.00456793911455264 2950 64 24 0.375 0.00813559322033898
TF TF:M10785 Factor: hoxa9; motif: RTCGTWANNN 0.00623464002597551 5632 34 22 0.647058823529412 0.00390625
TF TF:M10436_1 Factor: YY1; motif: CAANATGGCGGC; match class: 1 0.00733206212101061 2285 23 11 0.478260869565217 0.00481400437636762
TF TF:M00793 Factor: YY1; motif: GCCATNTTN 0.00733206212101061 5186 49 27 0.551020408163265 0.00520632472040108
TF TF:M11433_1 Factor: Elk-1; motif: NRCCGGAAGTN; match class: 1 0.00733206212101061 2261 64 20 0.3125 0.00884564352056612
TF TF:M04059 Factor: NRF-1; motif: YGCGCATGCGCN 0.00865314018517919 1471 53 14 0.264150943396226 0.00951733514615908
TF TF:M10018 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS 0.00880469581517257 1816 30 11 0.366666666666667 0.00605726872246696
TF TF:M11404_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.00880469581517257 3171 60 23 0.383333333333333 0.00725323241879533
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.00880469581517257 10939 55 45 0.818181818181818 0.0041137215467593
TF TF:M01752_1 Factor: ERG; motif: ACCGGAART; match class: 1 0.00880469581517257 3705 60 25 0.416666666666667 0.0067476383265857
TF TF:M07234 Factor: YY1; motif: CAARATGGCNGC 0.00880469581517257 6045 49 29 0.591836734693878 0.00479735318444996
TF TF:M10849_1 Factor: Cdx-2; motif: NRTCGTAANNNN; match class: 1 0.00880469581517257 4497 27 16 0.592592592592593 0.00355792750722704
TF TF:M07370 Factor: YY1; motif: NNNNAARATGGNNNN 0.00880469581517257 5811 49 28 0.571428571428571 0.00481844777146791
TF TF:M04696_1 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN; match class: 1 0.00880469581517257 1973 19 9 0.473684210526316 0.00456158134820071
TF TF:M00430 Factor: E2F-1; motif: NTTSGCGG 0.00880469581517257 8016 66 43 0.651515151515151 0.00536427145708583
TF TF:M10956 Factor: isx; motif: NTCRTTAA 0.00880469581517257 9441 28 24 0.857142857142857 0.00254210359072132
TF TF:M01744 Factor: REX1; motif: AANATGGCKGCN 0.00880469581517257 628 7 4 0.571428571428571 0.00636942675159236
TF TF:M02044 Factor: YY1; motif: GCCGCCATTTTG 0.00880469581517257 6102 56 32 0.571428571428571 0.00524418223533268
TF TF:M10783 Factor: hoxa9; motif: RTCGTWAANN 0.00880469581517257 1897 65 18 0.276923076923077 0.00948866631523458
TF TF:M03970_1 Factor: ELK1; motif: ACCGGAAGTN; match class: 1 0.00880469581517257 1097 64 13 0.203125 0.0118505013673655
TF TF:M07415_1 Factor: Elf-1; motif: AWCCCGGAAGTN; match class: 1 0.00880469581517257 2397 64 20 0.3125 0.00834376303712975
TF TF:M04696 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN 0.00880469581517257 7819 25 20 0.8 0.00255787185062028
TF TF:M08913_1 Factor: FLI-1; motif: NAYTTCCGGT; match class: 1 0.00880469581517257 3055 64 23 0.359375 0.00752864157119476
TF TF:M02073_1 Factor: Fli-1; motif: ACCGGAAGYN; match class: 1 0.0107547649449335 1488 64 15 0.234375 0.0100806451612903
TF TF:M10680 Factor: HPX42B; motif: CGATTANCG 0.0107547649449335 1321 8 5 0.625 0.00378501135503407
TF TF:M01035 Factor: YY1; motif: NYNKCCATNTT 0.0109545593601886 5924 33 21 0.636363636363636 0.00354490209318028
TF TF:M08213_1 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN; match class: 1 0.0113578880428357 1417 27 9 0.333333333333333 0.0063514467184192
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.0122852707977544 4963 57 28 0.491228070175439 0.00564174894217207
TF TF:M11620 Factor: Sox-14; motif: CCGAACAATN 0.0122852707977544 538 4 3 0.75 0.00557620817843866
TF TF:M00427 Factor: E2F; motif: TTTSGCGS 0.012345870573381 9485 41 32 0.780487804878049 0.00337374802319452
TF TF:M10638 Factor: Nkx2-3; motif: NNCGTTRWS 0.0125968035463681 10804 61 48 0.786885245901639 0.00444279896334691
TF TF:M00425 Factor: E2F; motif: TTTCGCGC 0.0128194774830851 11043 66 52 0.787878787878788 0.00470886534456217
TF TF:M12273_1 Factor: YY1; motif: GGCSGCCATTTTGN; match class: 1 0.0128194774830851 1261 19 7 0.368421052631579 0.00555114988104679
TF TF:M08222 Factor: Elk-1:HOXB13; motif: ACCGGAAGTNGTAAAN 0.0128194774830851 7653 60 38 0.633333333333333 0.00496537305631778
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0128194774830851 4902 24 15 0.625 0.00305997552019584
TF TF:M02053_1 Factor: ELF1; motif: NCCGGAARTN; match class: 1 0.0128194774830851 1559 64 15 0.234375 0.00962155227710071
TF TF:M03990_1 Factor: GABPA; motif: ACCGGAAGTN; match class: 1 0.0128194774830851 1206 64 13 0.203125 0.0107794361525705
TF TF:M00740 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC 0.0128194774830851 10427 66 50 0.757575757575758 0.00479524311882612
TF TF:M07250 Factor: E2F-1; motif: NNNSSCGCSAANN 0.0128194774830851 10703 57 45 0.789473684210526 0.00420442866486032
TF TF:M10625 Factor: Nkx3-2; motif: NTCGTTAN 0.0128194774830851 6062 56 31 0.553571428571429 0.00511382382052128
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.0133808140046892 3233 60 22 0.366666666666667 0.00680482523971543
TF TF:M00032_1 Factor: c-Ets-1(p54); motif: NCMGGAWGYN; match class: 1 0.0136596447908785 2161 64 18 0.28125 0.00832947709393799
TF TF:M08451_1 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA; match class: 1 0.0137729142490055 2584 64 20 0.3125 0.00773993808049536
TF TF:M11451_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.0137729142490055 2112 60 17 0.283333333333333 0.00804924242424242
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.0144284243468022 3759 60 24 0.4 0.00638467677573823
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.0145663101931184 4024 60 25 0.416666666666667 0.00621272365805169
TF TF:M07250_1 Factor: E2F-1; motif: NNNSSCGCSAANN; match class: 1 0.0145663101931184 5515 41 23 0.560975609756098 0.00417044424297371
TF TF:M04359 Factor: HOXD11; motif: RTCGTAAAAN 0.0146737546975571 469 65 8 0.123076923076923 0.0170575692963753
TF TF:M11327_1 Factor: DBP; motif: NRTTAYGTAAYN; match class: 1 0.0146737546975571 108 49 4 0.0816326530612245 0.037037037037037
TF TF:M00217_1 Factor: USF; motif: NCACGTGN; match class: 1 0.0150780424957314 1248 64 13 0.203125 0.0104166666666667
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.0152521966283596 8219 67 43 0.641791044776119 0.00523178002190047
TF TF:M03982_1 Factor: ETV4; motif: ACCGGAAGTN; match class: 1 0.0152521966283596 2009 64 17 0.265625 0.00846192135390742
TF TF:M02067_1 Factor: ER71; motif: ACCGGAARYN; match class: 1 0.0152521966283596 1619 64 15 0.234375 0.00926497838171711
TF TF:M12275_1 Factor: YY1; motif: NGCCGCCATYTTGN; match class: 1 0.0157813553444782 1600 65 15 0.230769230769231 0.009375
TF TF:M04694 Factor: NRF-1; motif: CNCTGCGCATGCGC 0.0168016327534184 1548 28 9 0.321428571428571 0.00581395348837209
TF TF:M03924 Factor: YY1; motif: NNCGCCATTNN 0.0168016327534184 10084 67 49 0.73134328358209 0.00485918286394288
TF TF:M12273 Factor: YY1; motif: GGCSGCCATTTTGN 0.0168016327534184 6229 49 28 0.571428571428571 0.00449510354792101
TF TF:M11765 Factor: TR2; motif: NRGGTCRYGACCYN 0.0170148555544195 3058 13 8 0.615384615384615 0.0026160889470242
TF TF:M10880_1 Factor: Alx-4; motif: NNCRTTAN; match class: 1 0.0170148555544195 2683 25 11 0.44 0.00409988818486769
TF TF:M10799 Factor: HOXA10; motif: NRTCGTAAANN 0.0174308760134581 5646 27 17 0.62962962962963 0.00301098122564648
TF TF:M10468_1 Factor: ZBRK1; motif: NGNNNGGTNAWAAAARRGCNG; match class: 1 0.0175900286307089 4669 51 24 0.470588235294118 0.00514028699935746
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.018620190172158 4677 57 26 0.456140350877193 0.00555911909343596
TF TF:M12275 Factor: YY1; motif: NGCCGCCATYTTGN 0.0189063945373173 7043 25 18 0.72 0.00255572909271617
TF TF:M02066_1 Factor: PEA3; motif: RCCGGAAGYN; match class: 1 0.0191183884333553 2283 64 18 0.28125 0.00788436268068331
TF TF:M08418_1 Factor: TEF-3:Elk-1; motif: RMATWCCGGAWGT; match class: 1 0.0194451623310984 5247 60 29 0.483333333333333 0.00552696779111873
TF TF:M09966_1 Factor: Kaiso; motif: SARNYCTCGCGAGAN; match class: 1 0.0200673147056038 449 26 5 0.192307692307692 0.0111358574610245
TF TF:M01372_1 Factor: NKX2B; motif: NNNRCCACTTGARANNN; match class: 1 0.0201222300528738 339 34 5 0.147058823529412 0.0147492625368732
TF TF:M07612 Factor: PSF; motif: KWATCCGN 0.0207820214810989 5581 30 18 0.6 0.00322522845368214
TF TF:M02102 Factor: NRF-1; motif: YGCGCMTGCGC 0.0208726427065282 2020 55 15 0.272727272727273 0.00742574257425743
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.0208726427065282 10488 28 24 0.857142857142857 0.0022883295194508
TF TF:M02071_1 Factor: ETV7; motif: NCCGGAANNN; match class: 1 0.0208726427065282 4465 60 26 0.433333333333333 0.00582306830907055
TF TF:M08377_1 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1 0.0208726427065282 5051 57 27 0.473684210526316 0.00534547614333795
TF TF:M10956_1 Factor: isx; motif: NTCRTTAA; match class: 1 0.0208726427065282 3336 25 12 0.48 0.00359712230215827
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.0208726427065282 6749 60 34 0.566666666666667 0.00503778337531486
TF TF:M02044_1 Factor: YY1; motif: GCCGCCATTTTG; match class: 1 0.0208726427065282 1198 62 12 0.193548387096774 0.010016694490818
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.0208726427065282 4201 60 25 0.416666666666667 0.0059509640561771
TF TF:M11320_1 Factor: C/EBPdelta; motif: NRTTGCGYAAYN; match class: 1 0.0208726427065282 2586 4 4 1 0.00154679040989946
TF TF:M11384 Factor: ESE-1; motif: ACCCGGAAGTRNNNNNNNWWWWW 0.0208726427065282 3272 67 23 0.343283582089552 0.00702933985330073
TF TF:M00426_1 Factor: E2F; motif: TTTSGCGS; match class: 1 0.0208958507706319 5830 27 17 0.62962962962963 0.00291595197255575
TF TF:M10849 Factor: Cdx-2; motif: NRTCGTAANNNN 0.0208958507706319 11163 27 24 0.888888888888889 0.00214995968825585
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.0213592092288537 4592 30 16 0.533333333333333 0.00348432055749129
TF TF:M00516 Factor: E2F-1; motif: TTTSGCGCGMNR 0.0213592092288537 6904 40 25 0.625 0.00362108922363847
TF TF:M12238 Factor: DREF; motif: MTRTCGCGAYAK 0.0213592092288537 350 53 6 0.113207547169811 0.0171428571428571
TF TF:M11225_1 Factor: CREM; motif: NNTGACGTCANN; match class: 1 0.0213592092288537 2482 51 16 0.313725490196078 0.0064464141821112
TF TF:M02074_1 Factor: GABPalpha; motif: RCCGGAWRYN; match class: 1 0.0213592092288537 1005 64 11 0.171875 0.0109452736318408
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.0213592092288537 11116 44 36 0.818181818181818 0.00323857502698813
TF TF:M11427_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0214101861223239 4606 30 16 0.533333333333333 0.00347372991749891
TF TF:M03924_1 Factor: YY1; motif: NNCGCCATTNN; match class: 1 0.0214645846649481 3700 57 22 0.385964912280702 0.00594594594594595
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.0214645846649481 14873 28 28 1 0.00188260606468097
TF TF:M04059_1 Factor: NRF-1; motif: YGCGCATGCGCN; match class: 1 0.0214645846649481 1033 53 10 0.188679245283019 0.00968054211035818
TF TF:M09607 Factor: SAP-1; motif: ACCGGAAGTNN 0.0219681445274226 4727 67 29 0.432835820895522 0.00613496932515337
TF TF:M04335_1 Factor: HMX3; motif: NNCAMTTAANN; match class: 1 0.0219681445274226 1267 52 11 0.211538461538462 0.00868192580899763
TF TF:M11005 Factor: LHX4; motif: NNCRTTAN 0.021992519550586 10614 28 24 0.857142857142857 0.00226116449971735
TF TF:M11447_1 Factor: Elf-1; motif: NAMCCGGAAGTN; match class: 1 0.0223918095447144 2593 64 19 0.296875 0.00732741997686078
TF TF:M10880 Factor: Alx-4; motif: NNCRTTAN 0.0224426649081323 8535 36 26 0.722222222222222 0.00304628002343292
TF TF:M11808_1 Factor: RAR-gamma; motif: NAGGTCANG; match class: 1 0.0224426649081323 123 56 4 0.0714285714285714 0.032520325203252
TF TF:M07370_1 Factor: YY1; motif: NNNNAARATGGNNNN; match class: 1 0.0228129882885194 1076 13 5 0.384615384615385 0.00464684014869888
TF TF:M10999 Factor: LIM-1; motif: NNCGTTAN 0.0228129882885194 5894 25 16 0.64 0.00271462504241602
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 0.0236951220317384 14997 28 28 1 0.0018670400746816
TF TF:M01864_1 Factor: ATF-4; motif: KACGTCAKS; match class: 1 0.0236951220317384 1239 7 4 0.571428571428571 0.00322841000807102
TF TF:M11223 Factor: CREB1; motif: NRTGACGTCANN 0.0236951220317384 2810 38 14 0.368421052631579 0.00498220640569395
TF TF:M00638 Factor: HNF4alpha; motif: VTGAACTTTGMMB 0.0236951220317384 2814 60 19 0.316666666666667 0.00675195451314854
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.0244574602930877 4607 60 26 0.433333333333333 0.00564358584762318
TF TF:M09606 Factor: nerf; motif: NRRNSCGGAAGNRNNNN 0.0244574602930877 6249 18 13 0.722222222222222 0.00208033285325652
TF TF:M03966 Factor: ELF1; motif: AACCCGGAAGTR 0.0253141894041064 6610 67 36 0.537313432835821 0.00544629349470499
TF TF:M03791_1 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY; match class: 1 0.0261038787926227 429 18 4 0.222222222222222 0.00932400932400932
TF TF:M09904_1 Factor: Elk-1; motif: RCCGGAAGTGN; match class: 1 0.0273663328820194 2743 67 20 0.298507462686567 0.00729128691213999
TF TF:M10578_1 Factor: Barhl-1; motif: NTAAACGN; match class: 1 0.0275124059069645 1391 22 7 0.318181818181818 0.00503235082674335
TF TF:M08756 Factor: Bach1; motif: ATGACTCAT 0.0275472965697111 198 17 3 0.176470588235294 0.0151515151515152
TF TF:M02073 Factor: Fli-1; motif: ACCGGAAGYN 0.0275472965697111 5839 57 29 0.508771929824561 0.00496660387052577
TF TF:M04213 Factor: JDP2; motif: ATGACTCAT 0.0275472965697111 198 17 3 0.176470588235294 0.0151515151515152
TF TF:M10591 Factor: BSX; motif: NNCGTTAN 0.0275472965697111 7760 28 20 0.714285714285714 0.00257731958762887
TF TF:M11260 Factor: NF-E2p45; motif: NATGASTCATN 0.0275472965697111 198 17 3 0.176470588235294 0.0151515151515152
TF TF:M11260_1 Factor: NF-E2p45; motif: NATGASTCATN; match class: 1 0.0275472965697111 198 17 3 0.176470588235294 0.0151515151515152
TF TF:M01078_1 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN; match class: 1 0.0275472965697111 2448 64 18 0.28125 0.00735294117647059
TF TF:M00098 Factor: Pax-2; motif: NNNNGTCANGNRTKANNNN 0.0275472965697111 7735 11 10 0.909090909090909 0.00129282482223659
TF TF:M11414 Factor: GABP-alpha; motif: NACCGGAAGTN 0.0275838592190083 2907 64 20 0.3125 0.00687994496044032
TF TF:M07234_1 Factor: YY1; motif: CAARATGGCNGC; match class: 1 0.0275838592190083 1177 19 6 0.315789473684211 0.00509770603228547
TF TF:M10948 Factor: rax; motif: NNCRTTAN 0.0277054410969647 11816 36 31 0.861111111111111 0.00262356127285037
TF TF:M04211 Factor: DBP; motif: NRTTACGTAAYN 0.0277725357382934 160 49 4 0.0816326530612245 0.025
TF TF:M04504 Factor: GMEB2; motif: TTACGTAA 0.0277725357382934 160 49 4 0.0816326530612245 0.025
TF TF:M04112_1 Factor: GMEB2; motif: TTACGYAM; match class: 1 0.0277725357382934 160 49 4 0.0816326530612245 0.025
TF TF:M08785 Factor: Sox-6; motif: CACCGAACAAT 0.0277725357382934 1105 4 3 0.75 0.00271493212669683
TF TF:M04504_1 Factor: GMEB2; motif: TTACGTAA; match class: 1 0.0277725357382934 160 49 4 0.0816326530612245 0.025
TF TF:M00738 Factor: E2F-4:DP-1; motif: TTTSGCGC 0.0277725357382934 9812 64 45 0.703125 0.00458622095393396
TF TF:M04211_1 Factor: DBP; motif: NRTTACGTAAYN; match class: 1 0.0277725357382934 160 49 4 0.0816326530612245 0.025
TF TF:M03925 Factor: YY2; motif: NCCGCCATNTY 0.0277725357382934 4641 23 13 0.565217391304348 0.00280112044817927
TF TF:M11018_1 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN; match class: 1 0.0277725357382934 15920 65 62 0.953846153846154 0.00389447236180905
TF TF:M01107 Factor: RUSH-1alpha; motif: NNMCWTNKNN 0.0280203981229054 3108 36 14 0.388888888888889 0.0045045045045045
TF TF:M07380 Factor: E2F-4; motif: NTTTCSCGCC 0.0281340257427659 13022 34 31 0.911764705882353 0.00238058669943173
TF TF:M10887 Factor: PRX-2; motif: NNCRTTAN 0.0281340257427659 5715 56 28 0.5 0.00489938757655293
TF TF:M00427_1 Factor: E2F; motif: TTTSGCGS; match class: 1 0.0281340257427659 3831 27 13 0.481481481481481 0.00339336987731663
TF TF:M00740_1 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC; match class: 1 0.0281340257427659 4583 26 14 0.538461538461538 0.00305476761946323
TF TF:M03971 Factor: ELK1; motif: NACTTCCGSCGGAAGYN 0.0281340257427659 11293 13 13 1 0.00115115558310458
TF TF:M11327 Factor: DBP; motif: NRTTAYGTAAYN 0.0281340257427659 163 49 4 0.0816326530612245 0.0245398773006135
TF TF:M10885 Factor: PRX-2; motif: NKCGTTAN 0.0281340257427659 5715 56 28 0.5 0.00489938757655293
TF TF:M02062_1 Factor: Erg; motif: ACCGGAAGTN; match class: 1 0.0281340257427659 2718 64 19 0.296875 0.00699043414275202
TF TF:M11434_1 Factor: Elk-1; motif: NRSCGGAAGNN; match class: 1 0.0281340257427659 2935 34 13 0.382352941176471 0.00442930153321976
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.0288070646190587 15260 28 28 1 0.0018348623853211
TF TF:M04225 Factor: TEF; motif: NRTTACRTAAYN 0.0288531225517581 72 49 3 0.0612244897959184 0.0416666666666667
TF TF:M01167 Factor: SAP-1a; motif: NACCGGAAGTV 0.0292420423288119 1948 27 9 0.333333333333333 0.00462012320328542
TF TF:M11331_1 Factor: Hlf; motif: NNTTACGTAANN; match class: 1 0.0292420423288119 168 49 4 0.0816326530612245 0.0238095238095238
TF TF:M11008 Factor: LHX4; motif: NTCRTTAN 0.0292420423288119 6586 28 18 0.642857142857143 0.00273307014880049
TF TF:M10795 Factor: HOXA10; motif: NGTCGTAAAAN 0.0292420423288119 6913 27 18 0.666666666666667 0.00260378996094315
TF TF:M00652 Factor: NRF-1; motif: CGCATGCGCR 0.0292420423288119 1376 30 8 0.266666666666667 0.00581395348837209
TF TF:M09608_1 Factor: Erg; motif: NNACCGGAARTSN; match class: 1 0.0292420423288119 2389 27 10 0.37037037037037 0.00418585182084554
TF TF:M11987 Factor: NFATc3; motif: NAYGGAAANW 0.0292420423288119 2409 56 16 0.285714285714286 0.0066417600664176
TF TF:M11307_1 Factor: ATF-2; motif: NNTGACGTMANN; match class: 1 0.0293198690164474 1946 38 11 0.289473684210526 0.00565262076053443
TF TF:M11223_1 Factor: CREB1; motif: NRTGACGTCANN; match class: 1 0.0296776026232608 2678 51 16 0.313725490196078 0.00597460791635549
TF TF:M11272_1 Factor: JunB; motif: NATGASTCAYN; match class: 1 0.0299081056196062 221 17 3 0.176470588235294 0.0135746606334842
TF TF:M08206_1 Factor: E2F-3:Prrxl1; motif: SGCGCTAATTNN; match class: 1 0.0311275561507396 5052 27 15 0.555555555555556 0.00296912114014252
TF TF:M09905_1 Factor: SAP-1; motif: NNCCGGAAGTGN; match class: 1 0.0311275561507396 2989 64 20 0.3125 0.00669120107059217
TF TF:M08390 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA 0.0311275561507396 11072 28 24 0.857142857142857 0.00216763005780347
TF TF:M11908 Factor: POU3F2; motif: TAATKAGNNNNTAATKA 0.0311275561507396 3695 22 11 0.5 0.00297699594046008
TF TF:M07140 Factor: Kaiso; motif: NTCTCGCGAGANYTN 0.0314887593319855 552 56 7 0.125 0.0126811594202899
TF TF:M01425 Factor: HNF-1beta; motif: NNNNGTTAACTAGNNNT 0.0314887593319855 5232 64 29 0.453125 0.00554281345565749
TF TF:M04748_1 Factor: GABP-alpha; motif: AACCGGAAR; match class: 1 0.0317096014097398 10368 15 14 0.933333333333333 0.00135030864197531
TF TF:M09976 Factor: LHX2; motif: NNYTAATTRNNN 0.0317096014097398 2364 5 4 0.8 0.00169204737732657
TF TF:M11225 Factor: CREM; motif: NNTGACGTCANN 0.0317096014097398 2710 51 16 0.313725490196078 0.00590405904059041
TF TF:M12238_1 Factor: DREF; motif: MTRTCGCGAYAK; match class: 1 0.0317096014097398 293 51 5 0.0980392156862745 0.0170648464163823
TF TF:M11817_1 Factor: T3R-beta; motif: NRRGGTCRTGACCYYN; match class: 1 0.0321929407479014 1566 11 5 0.454545454545455 0.00319284802043423
TF TF:M08206 Factor: E2F-3:Prrxl1; motif: SGCGCTAATTNN 0.0331647434531545 11802 27 24 0.888888888888889 0.00203355363497712
TF TF:M11299_1 Factor: jdp2; motif: NRTGASTCAYN; match class: 1 0.0331647434531545 235 17 3 0.176470588235294 0.0127659574468085
TF TF:M11415 Factor: GABP-alpha; motif: NRCCGGAAGTN 0.0334087568463631 3257 64 21 0.328125 0.00644765121277249
TF TF:M11439 Factor: Net; motif: NRCCGGAAGTN 0.0334087568463631 2568 64 18 0.28125 0.00700934579439252
TF TF:M09789 Factor: TFDP1; motif: NSGCGGGAANN 0.0335568075066703 2026 22 8 0.363636363636364 0.00394866732477789
TF TF:M00803 Factor: E2F; motif: GGCGSG 0.0335568075066703 13190 65 55 0.846153846153846 0.00416982562547384
TF TF:M11419_1 Factor: ER81; motif: NNCCGGAWGYN; match class: 1 0.0335568075066703 1427 60 12 0.2 0.00840925017519271
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.0335568075066703 7600 39 25 0.641025641025641 0.00328947368421053
TF TF:M01037 Factor: GLI; motif: NBTGGGTGGTCN 0.0335568075066703 2013 3 3 1 0.0014903129657228
TF TF:M11432_1 Factor: Elk-1; motif: NACMGGAAGTN; match class: 1 0.0335568075066703 1525 64 13 0.203125 0.00852459016393443
TF TF:M04802_1 Factor: c-Fos; motif: ACTCACCA; match class: 1 0.0335568075066703 1481 58 12 0.206896551724138 0.00810263335584065
TF TF:M08993 Factor: ZNF777; motif: GTCCGYCCCGTCSAACAAT 0.0336556671249431 10617 11 11 1 0.00103607422058962
TF TF:M09606_1 Factor: nerf; motif: NRRNSCGGAAGNRNNNN; match class: 1 0.0336556671249431 1704 51 12 0.235294117647059 0.00704225352112676
TF TF:M11428_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0336556671249431 2146 64 16 0.25 0.00745573159366263
TF TF:M03791 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY 0.0337029336227454 2969 27 11 0.407407407407407 0.00370495116200741
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.0337427383827975 8690 55 36 0.654545454545455 0.00414269275028769
TF TF:M11313_1 Factor: CREBPA; motif: NRTGACGTMANN; match class: 1 0.0341983508699372 2025 38 11 0.289473684210526 0.0054320987654321
TF TF:M04012 Factor: HSFY1; motif: TTTCGAACG 0.0345521689968997 1013 62 10 0.161290322580645 0.00987166831194472
TF TF:M08947_1 Factor: C-FOS; motif: NNNKATGACGTCATNNN; match class: 1 0.035402283395523 2723 38 13 0.342105263157895 0.00477414616232097
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.035402283395523 12550 58 48 0.827586206896552 0.00382470119521912
TF TF:M00144 Factor: Pax-5; motif: RRMSWGANWYCTNRAGCGKRACSRYNSM 0.0357327673604634 13205 23 22 0.956521739130435 0.00166603559257857
TF TF:M08339 Factor: HOXB2:Elf-1; motif: SCGGAAGTMRTTA 0.0362145273989105 1690 59 13 0.220338983050847 0.00769230769230769
TF TF:M05445 Factor: GATA-5; motif: TTAMCAR 0.0374406546574218 3283 48 17 0.354166666666667 0.00517819067925678
TF TF:M02063_1 Factor: c-ets-1; motif: ACCGGAWGTN; match class: 1 0.0375244450361882 2396 64 17 0.265625 0.00709515859766277
TF TF:M11316 Factor: C/EBPbeta; motif: NRTTGCGYAAYN 0.0377400356067373 5225 5 5 1 0.000956937799043062
TF TF:M11815_1 Factor: T3R-beta; motif: NNRGGTCRTGACCYNN; match class: 1 0.0378041489137483 1675 11 5 0.454545454545455 0.00298507462686567
TF TF:M00736 Factor: E2F-1:DP-1; motif: TTTCSCGC 0.038005777494693 10390 64 46 0.71875 0.00442733397497594
TF TF:M11418_1 Factor: ER81; motif: NRCMGGAWGNN; match class: 1 0.038005777494693 549 18 4 0.222222222222222 0.00728597449908925
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.0384932247565532 11728 44 36 0.818181818181818 0.00306957708049113
TF TF:M11830 Factor: LRH-1; motif: TGACCTTGRNYCAAGGTCA 0.0384932247565532 7061 44 26 0.590909090909091 0.00368219798895341
TF TF:M00050 Factor: E2F; motif: TTTSGCGC 0.0385498160352786 7056 66 36 0.545454545454545 0.00510204081632653
TF TF:M11307 Factor: ATF-2; motif: NNTGACGTMANN 0.0385498160352786 2085 61 15 0.245901639344262 0.00719424460431655
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.0385498160352786 4639 60 25 0.416666666666667 0.0053890924768269
TF TF:M04403 Factor: MNX1; motif: NNYAATTAAN 0.0398938545498642 2650 5 4 0.8 0.00150943396226415
TF TF:M10817 Factor: HOXC11; motif: NGTCGTAAANN 0.0398938545498642 566 59 7 0.11864406779661 0.0123674911660777
TF TF:M02271 Factor: HOXA5; motif: CDBWAATK 0.0402815287301051 1928 19 7 0.368421052631579 0.00363070539419087
TF TF:M04379_1 Factor: ISL2; motif: GCAMTTAR; match class: 1 0.0404137813886377 662 51 7 0.137254901960784 0.0105740181268882
TF TF:M04714_1 Factor: Elf-1; motif: ACTTCCGGG; match class: 1 0.041343568221615 2659 64 18 0.28125 0.00676946220383603
TF TF:M12280 Factor: MTF-1; motif: NTTTTGCACACGGCNNN 0.041343568221615 6897 24 16 0.666666666666667 0.00231984920980136
TF TF:M04698 Factor: GABP-alpha; motif: CACTTCCGG 0.0413822042032578 3196 67 21 0.313432835820896 0.00657071339173967
TF TF:M11031 Factor: Six-2; motif: NCGTATCRNN 0.0416725671498121 9204 12 11 0.916666666666667 0.00119513255106475
TF TF:M11379 Factor: ESE-1; motif: ACCCGGAAGTRNNNNNNNNWWWW 0.0416766829904894 3200 67 21 0.313432835820896 0.0065625
TF TF:M00122_1 Factor: USF; motif: NNRNCACGTGNYNN; match class: 1 0.0418373598280206 2413 20 8 0.4 0.00331537505180274
TF TF:M00122 Factor: USF; motif: NNRNCACGTGNYNN 0.0418373598280206 2413 20 8 0.4 0.00331537505180274
TF TF:M08220_1 Factor: Elk-1:HOXA3; motif: ACCGGWAATKRNNTNWCNNATTAN; match class: 1 0.0418373598280206 5350 59 27 0.457627118644068 0.00504672897196262
TF TF:M00426 Factor: E2F; motif: TTTSGCGS 0.0418373598280206 11885 41 34 0.829268292682927 0.00286074884307951
TF TF:M08922_1 Factor: JUNB:FRA-1; motif: NNRTGACTCATNN; match class: 1 0.0418373598280206 277 17 3 0.176470588235294 0.0108303249097473
TF TF:M01035_1 Factor: YY1; motif: NYNKCCATNTT; match class: 1 0.0418373598280206 1112 10 4 0.4 0.00359712230215827
TF TF:M04201_1 Factor: CEBPB; motif: ATTRCGCAAY; match class: 1 0.0424543117229512 1501 4 3 0.75 0.00199866755496336
TF TF:M09913 Factor: ER81; motif: NNCCGGAAGYG 0.0424543117229512 2871 60 18 0.3 0.00626959247648903
TF TF:M04212_1 Factor: HLF; motif: NNTTACRTAAYN; match class: 1 0.0430763085994055 95 49 3 0.0612244897959184 0.0315789473684211
TF TF:M02097_1 Factor: LHX3; motif: ATTAAW; match class: 1 0.0430763085994055 6508 43 24 0.558139534883721 0.00368776889981561
TF TF:M01702 Factor: GLI1; motif: GACCACCCAMG 0.043096597594801 2358 3 3 1 0.00127226463104326
TF TF:M08759_1 Factor: c-Ets-2; motif: NCCGGAAGTG; match class: 1 0.0432483545977864 2915 64 19 0.296875 0.0065180102915952
TF TF:M10104_1 Factor: YY1; motif: CAARATGGCGGC; match class: 1 0.0437696202905047 1138 10 4 0.4 0.00351493848857645
TF TF:M04201 Factor: CEBPB; motif: ATTRCGCAAY 0.0439983551775313 4048 4 4 1 0.000988142292490119
TF TF:M03925_1 Factor: YY2; motif: NCCGCCATNTY; match class: 1 0.0445427871383146 765 7 3 0.428571428571429 0.00392156862745098
TF TF:M09935 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN 0.0445427871383146 4420 67 26 0.388059701492537 0.00588235294117647
TF TF:M10584 Factor: Barhl2; motif: NTAAACGN 0.0445437912323128 1886 49 12 0.244897959183673 0.0063626723223754
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.0445722404249994 10765 55 41 0.745454545454545 0.00380863910822109
TF TF:M10018_1 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS; match class: 1 0.0447296577553897 851 53 8 0.150943396226415 0.00940070505287897
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.0456383037974533 7600 67 38 0.567164179104478 0.005
TF TF:M04723 Factor: Thap1; motif: SCGCCATSTTKGNTNMGGGCARNN 0.0456383037974533 12187 27 24 0.888888888888889 0.00196931156149996
TF TF:M11330_1 Factor: Hlf; motif: NGTTRYGYAANN; match class: 1 0.0456383037974533 213 49 4 0.0816326530612245 0.0187793427230047
TF TF:M11037 Factor: Six-6; motif: NNSTATCRNN 0.0459602743415338 5270 7 6 0.857142857142857 0.00113851992409867
TF TF:M09992_1 Factor: c-Myc; motif: NCCACGTGCNN; match class: 1 0.0460640742315544 1634 64 13 0.203125 0.00795593635250918
TF TF:M11798 Factor: NR1B2; motif: NAAAGGTCAN 0.0466045856625074 3294 7 5 0.714285714285714 0.00151791135397693
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.0473728974001745 11423 20 18 0.9 0.00157576818699116
TF TF:M00069_1 Factor: YY1; motif: NNNCGGCCATCTTGNCTSNW; match class: 1 0.0473728974001745 2205 66 16 0.242424242424242 0.0072562358276644
TF TF:M11394 Factor: Erg; motif: NACMGGAARTN 0.0473728974001745 4051 38 16 0.421052631578947 0.00394964206368798
TF TF:M09641 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN 0.0473728974001745 3222 55 18 0.327272727272727 0.00558659217877095
TF TF:M03805_1 Factor: YB-1; motif: CCAMTCNGMR; match class: 1 0.0473728974001745 3680 9 6 0.666666666666667 0.0016304347826087
TF TF:M01224 Factor: P50:RELA-P65; motif: GGANTTYCCCWN 0.0473728974001745 2329 26 9 0.346153846153846 0.0038643194504079
TF TF:M01145_1 Factor: c-Myc; motif: RACCACGTGCTC; match class: 1 0.0482091029230759 3448 64 21 0.328125 0.00609048723897912
TF TF:M04378_1 Factor: IRX5; motif: NWACAYRACAWN; match class: 1 0.0484763888299797 592 19 4 0.210526315789474 0.00675675675675676
TF TF:M10785_1 Factor: hoxa9; motif: RTCGTWANNN; match class: 1 0.0487298275277839 1160 24 6 0.25 0.00517241379310345
TF TF:M00055_1 Factor: N-Myc; motif: NNCCACGTGNNN; match class: 1 0.0487298275277839 1452 64 12 0.1875 0.00826446280991736
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.0487298275277839 8273 18 14 0.777777777777778 0.00169225190378339
TF TF:M11024 Factor: six4; motif: NCGTATCRTN 0.0493233140402912 5404 7 6 0.857142857142857 0.00111028867505551
TF TF:M10801 Factor: HOXA10; motif: NRTCGTAAANN 0.0493233140402912 3886 65 23 0.353846153846154 0.00591868244981987
TF TF:M01782 Factor: TR4; motif: AGGTCAAAGGTCA 0.0493233140402912 552 10 3 0.3 0.00543478260869565
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.0495070940527617 11275 67 50 0.746268656716418 0.00443458980044346
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.0499131636421604 13227 58 49 0.844827586206897 0.00370454373629697
WP WP:WP477 Cytoplasmic Ribosomal Proteins 1.05923582824717e-13 90 26 11 0.423076923076923 0.122222222222222
WP WP:WP107 Translation Factors 5.67413833217264e-08 53 34 7 0.205882352941176 0.132075471698113
WP WP:WP5027 nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell 0.000805498215627179 17 34 3 0.0882352941176471 0.176470588235294

pEpiTp16 transcription factor target enrichment of top program genes

TF enrichment of pEpiTp16
Possible regulators of activation of pEpiTp16 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.