pEpiTd02 program activity among Epithelial cells

Activation of pEpiTd02
pEpiTd02 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpiTd02 by different cell subtypes
pEpiTd02 gene program activation among cells of different subtypes (Epithelial cells).

pEpiTd02 top program genes

Top genes of pEpiTd02 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpiTd02 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpiTd02
pEpiTd02 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0006955 immune response 1.23450577091375e-09 2311 90 39 0.433333333333333 0.0168758113370835
GO:BP GO:0002376 immune system process 1.23450577091375e-09 3278 92 47 0.510869565217391 0.0143380109823063
GO:BP GO:0045087 innate immune response 1.59313836117362e-09 998 90 26 0.288888888888889 0.0260521042084168
GO:BP GO:1903900 regulation of viral life cycle 1.93241274754605e-09 153 99 13 0.131313131313131 0.0849673202614379
GO:BP GO:0002252 immune effector process 1.93241274754605e-09 1309 90 29 0.322222222222222 0.0221543162719633
GO:BP GO:0048525 negative regulation of viral process 2.1056261573548e-09 94 99 11 0.111111111111111 0.117021276595745
GO:BP GO:0006952 defense response 3.5079482906598e-09 1818 144 44 0.305555555555556 0.0242024202420242
GO:BP GO:0051607 defense response to virus 3.68790160115067e-09 267 131 17 0.129770992366412 0.0636704119850187
GO:BP GO:0140546 defense response to symbiont 3.68790160115067e-09 267 131 17 0.129770992366412 0.0636704119850187
GO:BP GO:0034097 response to cytokine 3.91616176386891e-09 1226 134 34 0.253731343283582 0.0277324632952692
GO:BP GO:0050792 regulation of viral process 4.59891716596846e-09 192 135 15 0.111111111111111 0.078125
GO:BP GO:0098542 defense response to other organism 6.79956962531567e-09 1218 131 33 0.251908396946565 0.0270935960591133
GO:BP GO:0043903 regulation of biological process involved in symbiotic interaction 8.02522901402836e-09 203 135 15 0.111111111111111 0.0738916256157636
GO:BP GO:0071345 cellular response to cytokine stimulus 8.02522901402836e-09 1132 134 32 0.238805970149254 0.0282685512367491
GO:BP GO:0045071 negative regulation of viral genome replication 3.99724423091265e-08 54 131 9 0.0687022900763359 0.166666666666667
GO:BP GO:0060337 type I interferon signaling pathway 4.74988836478108e-08 95 143 11 0.0769230769230769 0.115789473684211
GO:BP GO:0009605 response to external stimulus 4.74988836478108e-08 2944 93 41 0.440860215053763 0.0139266304347826
GO:BP GO:0071357 cellular response to type I interferon 5.03268345935469e-08 96 143 11 0.0769230769230769 0.114583333333333
GO:BP GO:0071310 cellular response to organic substance 5.10948490132003e-08 2776 145 53 0.36551724137931 0.0190922190201729
GO:BP GO:0043207 response to external biotic stimulus 6.50035305938268e-08 1594 131 36 0.274809160305344 0.0225846925972397
GO:BP GO:0051707 response to other organism 6.50035305938268e-08 1592 131 36 0.274809160305344 0.0226130653266332
GO:BP GO:0034340 response to type I interferon 7.17642906306897e-08 101 143 11 0.0769230769230769 0.108910891089109
GO:BP GO:0009607 response to biotic stimulus 9.4245663470062e-08 1626 131 36 0.274809160305344 0.022140221402214
GO:BP GO:0009615 response to virus 9.4245663470062e-08 364 143 18 0.125874125874126 0.0494505494505494
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 9.4245663470062e-08 2255 144 46 0.319444444444444 0.0203991130820399
GO:BP GO:0019058 viral life cycle 1.08239981888667e-07 353 99 15 0.151515151515152 0.0424929178470255
GO:BP GO:0010033 response to organic substance 1.08239981888667e-07 3412 145 59 0.406896551724138 0.0172919109026964
GO:BP GO:0007155 cell adhesion 3.96277134536018e-07 1492 123 32 0.260162601626016 0.0214477211796247
GO:BP GO:0022610 biological adhesion 4.29052696340273e-07 1499 123 32 0.260162601626016 0.0213475650433622
GO:BP GO:0019221 cytokine-mediated signaling pathway 5.37491062964689e-07 810 143 25 0.174825174825175 0.0308641975308642
GO:BP GO:0070887 cellular response to chemical stimulus 6.57897508972795e-07 3393 145 57 0.393103448275862 0.0167992926613616
GO:BP GO:0045069 regulation of viral genome replication 6.85974166214085e-07 84 55 7 0.127272727272727 0.0833333333333333
GO:BP GO:0007166 cell surface receptor signaling pathway 1.24370385027802e-06 3210 136 52 0.382352941176471 0.0161993769470405
GO:BP GO:0002274 myeloid leukocyte activation 1.95302130356539e-06 667 88 17 0.193181818181818 0.0254872563718141
GO:BP GO:0006950 response to stress 1.99262019174622e-06 4170 146 64 0.438356164383562 0.015347721822542
GO:BP GO:0048518 positive regulation of biological process 2.12046406607863e-06 6363 137 80 0.583941605839416 0.0125726858400126
GO:BP GO:0016192 vesicle-mediated transport 4.41864363394307e-06 2180 92 31 0.33695652173913 0.0142201834862385
GO:BP GO:0019079 viral genome replication 4.83270132292461e-06 131 135 10 0.0740740740740741 0.0763358778625954
GO:BP GO:0032940 secretion by cell 4.99924147422192e-06 1364 73 21 0.287671232876712 0.0153958944281525
GO:BP GO:0046903 secretion 5.12911124428776e-06 1501 73 22 0.301369863013699 0.0146568954030646
GO:BP GO:0023052 signaling 5.68545068900984e-06 6810 88 58 0.659090909090909 0.00851688693098385
GO:BP GO:0002443 leukocyte mediated immunity 7.03705996960233e-06 877 67 16 0.238805970149254 0.0182440136830103
GO:BP GO:0042221 response to chemical 7.03705996960233e-06 4781 145 68 0.468965517241379 0.0142229659067141
GO:BP GO:0044403 biological process involved in symbiotic interaction 7.03705996960233e-06 1001 135 25 0.185185185185185 0.024975024975025
GO:BP GO:0043312 neutrophil degranulation 7.03705996960233e-06 482 63 12 0.19047619047619 0.024896265560166
GO:BP GO:0002283 neutrophil activation involved in immune response 7.20343145689693e-06 485 63 12 0.19047619047619 0.0247422680412371
GO:BP GO:0140352 export from cell 8.05065048636654e-06 1418 73 21 0.287671232876712 0.0148095909732017
GO:BP GO:0016032 viral process 8.4938688886637e-06 942 135 24 0.177777777777778 0.0254777070063694
GO:BP GO:0002446 neutrophil mediated immunity 8.81319011431715e-06 497 63 12 0.19047619047619 0.0241448692152917
GO:BP GO:0042119 neutrophil activation 8.82678578855578e-06 498 63 12 0.19047619047619 0.0240963855421687
GO:BP GO:0007154 cell communication 9.66007402389186e-06 6829 93 60 0.645161290322581 0.00878605945233563
GO:BP GO:0036230 granulocyte activation 9.66007402389186e-06 504 63 12 0.19047619047619 0.0238095238095238
GO:BP GO:0031581 hemidesmosome assembly 9.95259898564145e-06 12 77 4 0.051948051948052 0.333333333333333
GO:BP GO:0008219 cell death 1.10423157095601e-05 2292 126 38 0.301587301587302 0.0165794066317627
GO:BP GO:0030198 extracellular matrix organization 1.33654964915408e-05 401 113 14 0.123893805309735 0.0349127182044888
GO:BP GO:0043062 extracellular structure organization 1.35303676794433e-05 402 113 14 0.123893805309735 0.0348258706467662
GO:BP GO:0045229 external encapsulating structure organization 1.4119062183696e-05 404 113 14 0.123893805309735 0.0346534653465347
GO:BP GO:0043299 leukocyte degranulation 1.64555889084108e-05 535 63 12 0.19047619047619 0.0224299065420561
GO:BP GO:0012501 programmed cell death 1.75340188366699e-05 2143 126 36 0.285714285714286 0.0167988800746617
GO:BP GO:0007165 signal transduction 1.77722197496304e-05 6309 92 56 0.608695652173913 0.00887620859090189
GO:BP GO:0048519 negative regulation of biological process 1.81206131135255e-05 5757 113 62 0.548672566371681 0.0107694980024318
GO:BP GO:0002275 myeloid cell activation involved in immune response 1.92034746048582e-05 547 63 12 0.19047619047619 0.0219378427787934
GO:BP GO:0002831 regulation of response to biotic stimulus 1.92034746048582e-05 415 131 15 0.114503816793893 0.036144578313253
GO:BP GO:0002444 myeloid leukocyte mediated immunity 2.04310642323381e-05 551 63 12 0.19047619047619 0.0217785843920145
GO:BP GO:0030155 regulation of cell adhesion 2.25304655222416e-05 748 119 19 0.159663865546218 0.0254010695187166
GO:BP GO:0032879 regulation of localization 2.4368252645263e-05 2872 123 42 0.341463414634146 0.0146239554317549
GO:BP GO:0071346 cellular response to interferon-gamma 2.64841895405675e-05 175 99 9 0.0909090909090909 0.0514285714285714
GO:BP GO:0050896 response to stimulus 3.45750419313587e-05 9407 71 57 0.802816901408451 0.00605931752949931
GO:BP GO:0062207 regulation of pattern recognition receptor signaling pathway 4.00603422123971e-05 108 124 8 0.0645161290322581 0.0740740740740741
GO:BP GO:0023051 regulation of signaling 5.13711349133294e-05 3578 87 37 0.425287356321839 0.0103409726103969
GO:BP GO:0048522 positive regulation of cellular process 5.2857882618422e-05 5757 88 50 0.568181818181818 0.00868507903421921
GO:BP GO:0034341 response to interferon-gamma 6.27595927011504e-05 196 99 9 0.0909090909090909 0.0459183673469388
GO:BP GO:0098609 cell-cell adhesion 6.27595927011504e-05 894 70 15 0.214285714285714 0.0167785234899329
GO:BP GO:0009966 regulation of signal transduction 7.01455920407078e-05 3165 125 44 0.352 0.0139020537124803
GO:BP GO:0034329 cell junction assembly 8.02355996569728e-05 438 123 14 0.113821138211382 0.0319634703196347
GO:BP GO:0032101 regulation of response to external stimulus 8.26497017343627e-05 1051 131 23 0.175572519083969 0.021883920076118
GO:BP GO:0051234 establishment of localization 8.46923621435299e-05 5372 92 49 0.532608695652174 0.00912137006701415
GO:BP GO:0001775 cell activation 8.60191742143507e-05 1495 144 30 0.208333333333333 0.020066889632107
GO:BP GO:1902531 regulation of intracellular signal transduction 9.06216309941403e-05 1842 125 31 0.248 0.0168295331161781
GO:BP GO:0010646 regulation of cell communication 9.06216309941403e-05 3543 125 47 0.376 0.013265594129269
GO:BP GO:0032103 positive regulation of response to external stimulus 0.000103142714609647 513 124 15 0.120967741935484 0.0292397660818713
GO:BP GO:0045055 regulated exocytosis 0.000106846631371349 785 63 13 0.206349206349206 0.0165605095541401
GO:BP GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.000123172383969869 33 124 5 0.0403225806451613 0.151515151515152
GO:BP GO:0031347 regulation of defense response 0.000123295764374992 704 143 19 0.132867132867133 0.0269886363636364
GO:BP GO:0035556 intracellular signal transduction 0.000134001885516138 2772 88 31 0.352272727272727 0.0111832611832612
GO:BP GO:0006915 apoptotic process 0.000174399887258687 1990 126 32 0.253968253968254 0.0160804020100503
GO:BP GO:0002366 leukocyte activation involved in immune response 0.000231690754837739 717 63 12 0.19047619047619 0.0167364016736402
GO:BP GO:0006810 transport 0.000231690754837739 5224 92 47 0.510869565217391 0.00899693721286371
GO:BP GO:0051716 cellular response to stimulus 0.000239737080394569 7781 126 79 0.626984126984127 0.0101529366405346
GO:BP GO:0002263 cell activation involved in immune response 0.000239737080394569 721 63 12 0.19047619047619 0.0166435506241331
GO:BP GO:0031349 positive regulation of defense response 0.000287719112994763 362 124 12 0.0967741935483871 0.0331491712707182
GO:BP GO:0002221 pattern recognition receptor signaling pathway 0.000295275526968431 213 143 10 0.0699300699300699 0.0469483568075117
GO:BP GO:0051179 localization 0.000299829370026512 6901 92 56 0.608695652173913 0.00811476597594551
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 0.000332695725334863 88 99 6 0.0606060606060606 0.0681818181818182
GO:BP GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 0.000406646291151118 73 124 6 0.0483870967741935 0.0821917808219178
GO:BP GO:0006887 exocytosis 0.000422813729816471 904 63 13 0.206349206349206 0.0143805309734513
GO:BP GO:0009611 response to wounding 0.000477306460853849 674 123 16 0.130081300813008 0.0237388724035608
GO:BP GO:0060700 regulation of ribonuclease activity 0.000477306460853849 9 99 3 0.0303030303030303 0.333333333333333
GO:BP GO:0098780 response to mitochondrial depolarisation 0.000477306460853849 20 42 3 0.0714285714285714 0.15
GO:BP GO:0045088 regulation of innate immune response 0.000477306460853849 309 84 9 0.107142857142857 0.029126213592233
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 0.000571609065376782 294 34 6 0.176470588235294 0.0204081632653061
GO:BP GO:1990778 protein localization to cell periphery 0.000585663140413729 338 121 11 0.0909090909090909 0.0325443786982249
GO:BP GO:0045321 leukocyte activation 0.000585663140413729 1332 144 26 0.180555555555556 0.0195195195195195
GO:BP GO:0002833 positive regulation of response to biotic stimulus 0.000605632746005433 250 82 8 0.0975609756097561 0.032
GO:BP GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 0.000689920497251963 24 124 4 0.032258064516129 0.166666666666667
GO:BP GO:0034109 homotypic cell-cell adhesion 0.000736425560599432 87 70 5 0.0714285714285714 0.0574712643678161
GO:BP GO:0034330 cell junction organization 0.00103317387746875 722 123 16 0.130081300813008 0.0221606648199446
GO:BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 0.00104128844248704 251 143 10 0.0699300699300699 0.0398406374501992
GO:BP GO:0006953 acute-phase response 0.00106924995815701 50 66 4 0.0606060606060606 0.08
GO:BP GO:0009888 tissue development 0.00106924995815701 2107 114 29 0.254385964912281 0.0137636449928809
GO:BP GO:0048583 regulation of response to stimulus 0.00106924995815701 4278 125 50 0.4 0.0116877045348294
GO:BP GO:0039530 MDA-5 signaling pathway 0.00117391146376144 10 124 3 0.0241935483870968 0.3
GO:BP GO:0065009 regulation of molecular function 0.00121822611632081 3221 146 46 0.315068493150685 0.0142812791058677
GO:BP GO:0048584 positive regulation of response to stimulus 0.00122017206721687 2344 125 33 0.264 0.0140784982935154
GO:BP GO:0046578 regulation of Ras protein signal transduction 0.00133851758868944 199 116 8 0.0689655172413793 0.0402010050251256
GO:BP GO:0051056 regulation of small GTPase mediated signal transduction 0.00153036150346817 328 116 10 0.0862068965517241 0.0304878048780488
GO:BP GO:0048523 negative regulation of cellular process 0.00153036150346817 5139 63 33 0.523809523809524 0.00642148277875073
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 0.00153036150346817 1202 122 21 0.172131147540984 0.0174708818635607
GO:BP GO:0002526 acute inflammatory response 0.00181134889034431 114 66 5 0.0757575757575758 0.043859649122807
GO:BP GO:0051641 cellular localization 0.00182596085874343 3541 63 26 0.412698412698413 0.00734255859926574
GO:BP GO:0051701 biological process involved in interaction with host 0.00191706259516548 221 82 7 0.0853658536585366 0.0316742081447964
GO:BP GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 0.00191954349157777 66 116 5 0.0431034482758621 0.0757575757575758
GO:BP GO:0042060 wound healing 0.00245957816104146 549 122 13 0.10655737704918 0.0236794171220401
GO:BP GO:0071356 cellular response to tumor necrosis factor 0.0027033377531213 306 134 10 0.0746268656716418 0.0326797385620915
GO:BP GO:0044093 positive regulation of molecular function 0.0027044536328772 1771 128 27 0.2109375 0.0152456239412761
GO:BP GO:0039535 regulation of RIG-I signaling pathway 0.00273004386862902 20 82 3 0.0365853658536585 0.15
GO:BP GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus 0.00288540687057034 12 144 3 0.0208333333333333 0.25
GO:BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 0.00298031914880134 291 143 10 0.0699300699300699 0.0343642611683849
GO:BP GO:0032880 regulation of protein localization 0.00301022800941231 922 66 12 0.181818181818182 0.0130151843817787
GO:BP GO:0007229 integrin-mediated signaling pathway 0.00301324559339607 111 123 6 0.0487804878048781 0.0540540540540541
GO:BP GO:0045216 cell-cell junction organization 0.00311232952155932 216 123 8 0.0650406504065041 0.037037037037037
GO:BP GO:0051649 establishment of localization in cell 0.0032128939455753 2813 63 22 0.349206349206349 0.00782083185211518
GO:BP GO:0072659 protein localization to plasma membrane 0.00321548746464275 283 121 9 0.0743801652892562 0.0318021201413428
GO:BP GO:0001704 formation of primary germ layer 0.00322769118358525 123 113 6 0.0530973451327434 0.0487804878048781
GO:BP GO:0001817 regulation of cytokine production 0.0032633028522304 806 124 16 0.129032258064516 0.0198511166253102
GO:BP GO:0098586 cellular response to virus 0.00352962326281272 72 124 5 0.0403225806451613 0.0694444444444444
GO:BP GO:0016477 cell migration 0.00357129916617664 1649 70 17 0.242857142857143 0.0103092783505155
GO:BP GO:0009653 anatomical structure morphogenesis 0.00364192768367229 2797 141 39 0.276595744680851 0.0139435109045406
GO:BP GO:0030855 epithelial cell differentiation 0.00367940534574089 798 114 15 0.131578947368421 0.018796992481203
GO:BP GO:0052126 movement in host environment 0.00386364658121411 177 82 6 0.0731707317073171 0.0338983050847458
GO:BP GO:0030029 actin filament-based process 0.00390267501147354 808 139 17 0.122302158273381 0.021039603960396
GO:BP GO:0006809 nitric oxide biosynthetic process 0.00404847409953824 82 113 5 0.0442477876106195 0.0609756097560976
GO:BP GO:1903320 regulation of protein modification by small protein conjugation or removal 0.00413350384317783 243 39 5 0.128205128205128 0.0205761316872428
GO:BP GO:0010647 positive regulation of cell communication 0.00422102153151071 1777 125 26 0.208 0.0146314012380416
GO:BP GO:0045089 positive regulation of innate immune response 0.00423792117904414 216 69 6 0.0869565217391304 0.0277777777777778
GO:BP GO:0040011 locomotion 0.00429115771984 2028 70 19 0.271428571428571 0.00936883629191321
GO:BP GO:0034612 response to tumor necrosis factor 0.00429115771984 331 134 10 0.0746268656716418 0.0302114803625378
GO:BP GO:0045429 positive regulation of nitric oxide biosynthetic process 0.00429115771984 45 113 4 0.0353982300884956 0.0888888888888889
GO:BP GO:0023056 positive regulation of signaling 0.00429115771984 1782 125 26 0.208 0.0145903479236813
GO:BP GO:0034110 regulation of homotypic cell-cell adhesion 0.00448033149040121 29 70 3 0.0428571428571429 0.103448275862069
GO:BP GO:1904407 positive regulation of nitric oxide metabolic process 0.0045340865533523 46 113 4 0.0353982300884956 0.0869565217391304
GO:BP GO:0006954 inflammatory response 0.00453801529598843 794 144 17 0.118055555555556 0.0214105793450882
GO:BP GO:0001816 cytokine production 0.00487781986838732 844 124 16 0.129032258064516 0.018957345971564
GO:BP GO:0046209 nitric oxide metabolic process 0.00490578175537275 87 113 5 0.0442477876106195 0.0574712643678161
GO:BP GO:0060429 epithelium development 0.00490578175537275 1325 114 20 0.175438596491228 0.0150943396226415
GO:BP GO:0039529 RIG-I signaling pathway 0.00491522162038066 26 82 3 0.0365853658536585 0.115384615384615
GO:BP GO:0046718 viral entry into host cell 0.00491522162038066 141 70 5 0.0714285714285714 0.0354609929078014
GO:BP GO:0008544 epidermis development 0.00497539835457982 475 79 9 0.113924050632911 0.0189473684210526
GO:BP GO:0050790 regulation of catalytic activity 0.00497539835457982 2545 131 34 0.259541984732824 0.0133595284872299
GO:BP GO:2001057 reactive nitrogen species metabolic process 0.00501593925555161 88 113 5 0.0442477876106195 0.0568181818181818
GO:BP GO:0032069 regulation of nuclease activity 0.00502816169189057 22 99 3 0.0303030303030303 0.136363636363636
GO:BP GO:1903901 negative regulation of viral life cycle 0.0052357665762805 26 85 3 0.0352941176470588 0.115384615384615
GO:BP GO:0009893 positive regulation of metabolic process 0.00540611318259348 3783 113 40 0.353982300884956 0.0105736188210415
GO:BP GO:0080134 regulation of response to stress 0.0055340841694956 1443 131 23 0.175572519083969 0.0159390159390159
GO:BP GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 0.005886573871142 77 30 3 0.1 0.038961038961039
GO:BP GO:2000377 regulation of reactive oxygen species metabolic process 0.00600172813355747 203 12 3 0.25 0.0147783251231527
GO:BP GO:0065008 regulation of biological quality 0.00610022009608977 4131 146 52 0.356164383561644 0.0125877511498427
GO:BP GO:0006464 cellular protein modification process 0.00619262712000993 4041 128 46 0.359375 0.0113833209601584
GO:BP GO:0036211 protein modification process 0.00619262712000993 4041 128 46 0.359375 0.0113833209601584
GO:BP GO:0008360 regulation of cell shape 0.00653411721128447 154 70 5 0.0714285714285714 0.0324675324675325
GO:BP GO:0016043 cellular component organization 0.00653411721128447 6566 124 64 0.516129032258065 0.00974718245507158
GO:BP GO:0044409 entry into host 0.00653411721128447 154 70 5 0.0714285714285714 0.0324675324675325
GO:BP GO:0051128 regulation of cellular component organization 0.00653411721128447 2412 124 31 0.25 0.0128524046434494
GO:BP GO:0050708 regulation of protein secretion 0.00655310880360813 295 80 7 0.0875 0.023728813559322
GO:BP GO:0043297 apical junction assembly 0.00665334368186187 88 123 5 0.040650406504065 0.0568181818181818
GO:BP GO:0002064 epithelial cell development 0.00681470207744349 218 143 8 0.0559440559440559 0.036697247706422
GO:BP GO:0030036 actin cytoskeleton organization 0.00703097710864895 709 139 15 0.107913669064748 0.0211565585331453
GO:BP GO:0007264 small GTPase mediated signal transduction 0.00703097710864895 515 78 9 0.115384615384615 0.0174757281553398
GO:BP GO:0031281 positive regulation of cyclase activity 0.00703097710864895 21 122 3 0.0245901639344262 0.142857142857143
GO:BP GO:0009968 negative regulation of signal transduction 0.00703097710864895 1364 124 21 0.169354838709677 0.0153958944281525
GO:BP GO:0016050 vesicle organization 0.00703097710864895 341 142 10 0.0704225352112676 0.0293255131964809
GO:BP GO:1901564 organonitrogen compound metabolic process 0.00703097710864895 6792 36 24 0.666666666666667 0.00353356890459364
GO:BP GO:0010648 negative regulation of cell communication 0.00705021251778915 1468 124 22 0.17741935483871 0.0149863760217984
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.00705021251778915 1082 39 9 0.230769230769231 0.00831792975970425
GO:BP GO:0035666 TRIF-dependent toll-like receptor signaling pathway 0.00705021251778915 30 86 3 0.0348837209302326 0.1
GO:BP GO:0051049 regulation of transport 0.00705021251778915 1809 122 25 0.204918032786885 0.0138197899391929
GO:BP GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 0.00705021251778915 167 67 5 0.0746268656716418 0.029940119760479
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.00705021251778915 549 142 13 0.0915492957746479 0.0236794171220401
GO:BP GO:0022604 regulation of cell morphogenesis 0.00705021251778915 309 78 7 0.0897435897435897 0.0226537216828479
GO:BP GO:0030168 platelet activation 0.00705021251778915 160 70 5 0.0714285714285714 0.03125
GO:BP GO:0023057 negative regulation of signaling 0.00705021251778915 1471 124 22 0.17741935483871 0.0149558123725357
GO:BP GO:0048468 cell development 0.0072280805240623 2100 143 31 0.216783216783217 0.0147619047619048
GO:BP GO:0007265 Ras protein signal transduction 0.00735308343636244 349 116 9 0.0775862068965517 0.0257879656160458
GO:BP GO:0071840 cellular component organization or biogenesis 0.00741448188464837 6760 124 65 0.524193548387097 0.00961538461538462
GO:BP GO:0007044 cell-substrate junction assembly 0.00751471475906119 101 113 5 0.0442477876106195 0.0495049504950495
GO:BP GO:0032481 positive regulation of type I interferon production 0.00751471475906119 80 143 5 0.034965034965035 0.0625
GO:BP GO:0000902 cell morphogenesis 0.00775264632079454 1037 78 13 0.166666666666667 0.0125361620057859
GO:BP GO:0048870 cell motility 0.00791122807531272 1828 70 17 0.242857142857143 0.00929978118161926
GO:BP GO:0051674 localization of cell 0.00791122807531272 1828 70 17 0.242857142857143 0.00929978118161926
GO:BP GO:0022407 regulation of cell-cell adhesion 0.00792471638601796 445 7 3 0.428571428571429 0.00674157303370787
GO:BP GO:0006820 anion transport 0.00792471638601796 2889 80 25 0.3125 0.00865351332641052
GO:BP GO:2000249 regulation of actin cytoskeleton reorganization 0.00811909616313498 40 70 3 0.0428571428571429 0.075
GO:BP GO:0043412 macromolecule modification 0.00837496157021866 4257 128 47 0.3671875 0.0110406389476157
GO:BP GO:0042058 regulation of epidermal growth factor receptor signaling pathway 0.00857564574502483 90 32 3 0.09375 0.0333333333333333
GO:BP GO:0046596 regulation of viral entry into host cell 0.00861076769168389 43 67 3 0.0447761194029851 0.0697674418604651
GO:BP GO:0016266 O-glycan processing 0.00861076769168389 58 117 4 0.0341880341880342 0.0689655172413793
GO:BP GO:0009967 positive regulation of signal transduction 0.00864323020244931 1598 125 23 0.184 0.0143929912390488
GO:BP GO:0034121 regulation of toll-like receptor signaling pathway 0.00864323020244931 79 86 4 0.0465116279069767 0.0506329113924051
GO:BP GO:0002756 MyD88-independent toll-like receptor signaling pathway 0.00872170442177906 34 86 3 0.0348837209302326 0.0882352941176471
GO:BP GO:2000379 positive regulation of reactive oxygen species metabolic process 0.00872170442177906 107 113 5 0.0442477876106195 0.0467289719626168
GO:BP GO:0150115 cell-substrate junction organization 0.00872170442177906 107 113 5 0.0442477876106195 0.0467289719626168
GO:BP GO:0033036 macromolecule localization 0.0087683577744291 3218 123 37 0.300813008130081 0.0114978247358608
GO:BP GO:0007043 cell-cell junction assembly 0.00898108425144775 151 123 6 0.0487804878048781 0.0397350993377483
GO:BP GO:0032479 regulation of type I interferon production 0.00898108425144775 130 143 6 0.041958041958042 0.0461538461538462
GO:BP GO:0002791 regulation of peptide secretion 0.00898108425144775 325 80 7 0.0875 0.0215384615384615
GO:BP GO:0065007 biological regulation 0.00902624344784768 12809 96 82 0.854166666666667 0.00640174877039582
GO:BP GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 0.0090813991435749 100 30 3 0.1 0.03
GO:BP GO:0032606 type I interferon production 0.0090813991435749 131 143 6 0.041958041958042 0.0458015267175573
GO:BP GO:1903530 regulation of secretion by cell 0.0090813991435749 588 105 11 0.104761904761905 0.0187074829931973
GO:BP GO:1903428 positive regulation of reactive oxygen species biosynthetic process 0.0090813991435749 62 113 4 0.0353982300884956 0.0645161290322581
GO:BP GO:0051248 negative regulation of protein metabolic process 0.00909712048498999 1151 39 9 0.230769230769231 0.00781928757602085
GO:BP GO:0071702 organic substance transport 0.00918924911506092 2766 80 24 0.3 0.00867678958785249
GO:BP GO:0048585 negative regulation of response to stimulus 0.00918924911506092 1733 124 24 0.193548387096774 0.0138488170802077
GO:BP GO:0050789 regulation of biological process 0.00931148628673213 12091 95 78 0.821052631578947 0.00645107931519312
GO:BP GO:1901184 regulation of ERBB signaling pathway 0.00934393269584565 97 32 3 0.09375 0.0309278350515464
GO:BP GO:0048598 embryonic morphogenesis 0.00949891733332502 595 122 12 0.0983606557377049 0.0201680672268908
GO:BP GO:0000422 autophagy of mitochondrion 0.00960342541942799 75 42 3 0.0714285714285714 0.04
GO:BP GO:0061726 mitochondrion disassembly 0.00960342541942799 75 42 3 0.0714285714285714 0.04
GO:BP GO:0043331 response to dsRNA 0.00984570845176663 56 131 4 0.0305343511450382 0.0714285714285714
GO:BP GO:0043086 negative regulation of catalytic activity 0.00984872144098002 851 33 7 0.212121212121212 0.0082256169212691
GO:BP GO:0050794 regulation of cellular process 0.010231591240728 11473 95 75 0.789473684210526 0.00653708707399983
GO:BP GO:0031532 actin cytoskeleton reorganization 0.010247078143229 106 70 4 0.0571428571428571 0.0377358490566038
GO:BP GO:0098876 vesicle-mediated transport to the plasma membrane 0.0104604329917889 96 78 4 0.0512820512820513 0.0416666666666667
GO:BP GO:0097190 apoptotic signaling pathway 0.0104604329917889 600 34 6 0.176470588235294 0.01
GO:BP GO:0030330 DNA damage response, signal transduction by p53 class mediator 0.0104604329917889 110 30 3 0.1 0.0272727272727273
GO:BP GO:0072593 reactive oxygen species metabolic process 0.0105788316758253 290 12 3 0.25 0.0103448275862069
GO:BP GO:0007009 plasma membrane organization 0.0109252541198562 116 114 5 0.043859649122807 0.0431034482758621
GO:BP GO:0052372 modulation by symbiont of entry into host 0.0109536025219024 50 67 3 0.0447761194029851 0.06
GO:BP GO:1904375 regulation of protein localization to cell periphery 0.0110247068492117 126 61 4 0.0655737704918033 0.0317460317460317
GO:BP GO:0045428 regulation of nitric oxide biosynthetic process 0.0110247068492117 68 113 4 0.0353982300884956 0.0588235294117647
GO:BP GO:0007162 negative regulation of cell adhesion 0.0113522448531403 304 119 8 0.0672268907563025 0.0263157894736842
GO:BP GO:0002682 regulation of immune system process 0.0115572963565029 1617 144 25 0.173611111111111 0.015460729746444
GO:BP GO:0006928 movement of cell or subcellular component 0.0116449077500094 2311 70 19 0.271428571428571 0.00822154911293812
GO:BP GO:0032970 regulation of actin filament-based process 0.011790233321115 406 70 7 0.1 0.0172413793103448
GO:BP GO:0080164 regulation of nitric oxide metabolic process 0.011790233321115 70 113 4 0.0353982300884956 0.0571428571428571
GO:BP GO:0062208 positive regulation of pattern recognition receptor signaling pathway 0.0118568694128937 43 82 3 0.0365853658536585 0.0697674418604651
GO:BP GO:0051239 regulation of multicellular organismal process 0.0119290834739752 2861 146 38 0.26027397260274 0.0132820692065711
GO:BP GO:0002224 toll-like receptor signaling pathway 0.0121594613949568 161 86 5 0.0581395348837209 0.031055900621118
GO:BP GO:1901698 response to nitrogen compound 0.0125738287620711 1172 145 20 0.137931034482759 0.0170648464163823
GO:BP GO:0007369 gastrulation 0.0125738287620711 185 113 6 0.0530973451327434 0.0324324324324324
GO:BP GO:0031396 regulation of protein ubiquitination 0.0125738287620711 211 39 4 0.102564102564103 0.018957345971564
GO:BP GO:0010811 positive regulation of cell-substrate adhesion 0.0126152675414629 124 113 5 0.0442477876106195 0.0403225806451613
GO:BP GO:0052548 regulation of endopeptidase activity 0.0126268179175533 437 33 5 0.151515151515152 0.011441647597254
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0127623282828002 253 33 4 0.121212121212121 0.0158102766798419
GO:BP GO:0071496 cellular response to external stimulus 0.0127623282828002 322 144 9 0.0625 0.0279503105590062
GO:BP GO:0010256 endomembrane system organization 0.0128517511881804 484 78 8 0.102564102564103 0.0165289256198347
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0130849005152817 2541 33 12 0.363636363636364 0.00472255017709563
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.0139576949096477 1455 86 16 0.186046511627907 0.0109965635738832
GO:BP GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 0.0143339472197083 277 107 7 0.0654205607476635 0.0252707581227437
GO:BP GO:0070830 bicellular tight junction assembly 0.0143339472197083 80 107 4 0.0373831775700935 0.05
GO:BP GO:0007173 epidermal growth factor receptor signaling pathway 0.0145018830505149 123 32 3 0.09375 0.024390243902439
GO:BP GO:0051046 regulation of secretion 0.0145073153518712 647 105 11 0.104761904761905 0.0170015455950541
GO:BP GO:0010466 negative regulation of peptidase activity 0.0146860216904213 267 33 4 0.121212121212121 0.0149812734082397
GO:BP GO:0006898 receptor-mediated endocytosis 0.0146860216904213 333 90 7 0.0777777777777778 0.021021021021021
GO:BP GO:0001974 blood vessel remodeling 0.0149957319859881 46 87 3 0.0344827586206897 0.0652173913043478
GO:BP GO:0120192 tight junction assembly 0.0150185730656627 82 107 4 0.0373831775700935 0.0487804878048781
GO:BP GO:0042770 signal transduction in response to DNA damage 0.0150328737745823 135 30 3 0.1 0.0222222222222222
GO:BP GO:0052547 regulation of peptidase activity 0.0153517202173461 467 33 5 0.151515151515152 0.0107066381156317
GO:BP GO:0070201 regulation of establishment of protein localization 0.0153796357376245 611 80 9 0.1125 0.0147299509001637
GO:BP GO:0002684 positive regulation of immune system process 0.0155295840879501 1065 86 13 0.151162790697674 0.0122065727699531
GO:BP GO:0009306 protein secretion 0.0160080866954811 384 80 7 0.0875 0.0182291666666667
GO:BP GO:0007492 endoderm development 0.0161440427362264 80 113 4 0.0353982300884956 0.05
GO:BP GO:0035592 establishment of protein localization to extracellular region 0.0161440427362264 385 80 7 0.0875 0.0181818181818182
GO:BP GO:0050793 regulation of developmental process 0.0161440427362264 2605 70 20 0.285714285714286 0.00767754318618042
GO:BP GO:1903322 positive regulation of protein modification by small protein conjugation or removal 0.0161440427362264 140 30 3 0.1 0.0214285714285714
GO:BP GO:1903409 reactive oxygen species biosynthetic process 0.0161440427362264 135 113 5 0.0442477876106195 0.037037037037037
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.0161985091211186 1042 78 12 0.153846153846154 0.0115163147792706
GO:BP GO:0031400 negative regulation of protein modification process 0.0163437143007331 578 8 3 0.375 0.00519031141868512
GO:BP GO:0022607 cellular component assembly 0.0165212994371191 3010 124 34 0.274193548387097 0.0112956810631229
GO:BP GO:0045785 positive regulation of cell adhesion 0.0168099527519785 437 113 9 0.079646017699115 0.0205949656750572
GO:BP GO:0000266 mitochondrial fission 0.0168389523355111 41 104 3 0.0288461538461538 0.0731707317073171
GO:BP GO:0071692 protein localization to extracellular region 0.0173036350284595 392 80 7 0.0875 0.0178571428571429
GO:BP GO:0031401 positive regulation of protein modification process 0.0173245318470554 1074 39 8 0.205128205128205 0.0074487895716946
GO:BP GO:0120193 tight junction organization 0.0173245318470554 87 107 4 0.0373831775700935 0.0459770114942529
GO:BP GO:0043112 receptor metabolic process 0.0173245318470554 174 90 5 0.0555555555555556 0.028735632183908
GO:BP GO:0008104 protein localization 0.01751261849334 2770 145 36 0.248275862068966 0.0129963898916968
GO:BP GO:0009719 response to endogenous stimulus 0.01751261849334 1683 145 25 0.172413793103448 0.0148544266191325
GO:BP GO:0030501 positive regulation of bone mineralization 0.0178242731214467 39 113 3 0.0265486725663717 0.0769230769230769
GO:BP GO:0099637 neurotransmitter receptor transport 0.0179515261778877 49 90 3 0.0333333333333333 0.0612244897959184
GO:BP GO:0043067 regulation of programmed cell death 0.0179751755289069 1582 146 24 0.164383561643836 0.0151706700379267
GO:BP GO:0035023 regulation of Rho protein signal transduction 0.0179751755289069 86 110 4 0.0363636363636364 0.0465116279069767
GO:BP GO:0031399 regulation of protein modification process 0.0179772142936995 1671 32 9 0.28125 0.00538599640933573
GO:BP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 0.0181278795704841 369 136 9 0.0661764705882353 0.024390243902439
GO:BP GO:0032728 positive regulation of interferon-beta production 0.0181278795704841 36 124 3 0.0241935483870968 0.0833333333333333
GO:BP GO:1903008 organelle disassembly 0.0183170398628374 107 42 3 0.0714285714285714 0.0280373831775701
GO:BP GO:0070527 platelet aggregation 0.0183170398628374 64 70 3 0.0428571428571429 0.046875
GO:BP GO:0007015 actin filament organization 0.0184121750936713 445 136 10 0.0735294117647059 0.0224719101123595
GO:BP GO:1903034 regulation of response to wounding 0.0184479022663062 169 27 3 0.111111111111111 0.0177514792899408
GO:BP GO:0051246 regulation of protein metabolic process 0.0184479022663062 2704 33 12 0.363636363636364 0.00443786982248521
GO:BP GO:0060341 regulation of cellular localization 0.0184479022663062 851 137 15 0.109489051094891 0.0176263219741481
GO:BP GO:0031324 negative regulation of cellular metabolic process 0.0186600037958779 2719 21 9 0.428571428571429 0.00331004045605002
GO:BP GO:1901699 cellular response to nitrogen compound 0.0188025761625764 724 145 14 0.096551724137931 0.0193370165745856
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.0190255278071639 1037 125 16 0.128 0.0154291224686596
GO:BP GO:0038127 ERBB signaling pathway 0.0192396628600137 145 32 3 0.09375 0.0206896551724138
GO:BP GO:0051336 regulation of hydrolase activity 0.0192396628600137 1321 146 21 0.143835616438356 0.0158970476911431
GO:BP GO:0030162 regulation of proteolysis 0.0193704509898188 752 33 6 0.181818181818182 0.00797872340425532
GO:BP GO:0035295 tube development 0.0196933363023785 1146 146 19 0.13013698630137 0.0165794066317627
GO:BP GO:0007596 blood coagulation 0.0200587578191993 347 70 6 0.0857142857142857 0.0172910662824208
GO:BP GO:0007599 hemostasis 0.0208256924453071 351 70 6 0.0857142857142857 0.0170940170940171
GO:BP GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 0.0208256924453071 106 95 4 0.0421052631578947 0.0377358490566038
GO:BP GO:0001558 regulation of cell growth 0.020990118269195 426 78 7 0.0897435897435897 0.0164319248826291
GO:BP GO:0006893 Golgi to plasma membrane transport 0.0211352336205654 62 78 3 0.0384615384615385 0.0483870967741935
GO:BP GO:0050817 coagulation 0.021307984820977 354 70 6 0.0857142857142857 0.0169491525423729
GO:BP GO:0050878 regulation of body fluid levels 0.0215931289551731 514 122 10 0.0819672131147541 0.0194552529182879
GO:BP GO:0002790 peptide secretion 0.0220647972929952 421 80 7 0.0875 0.0166270783847981
GO:BP GO:0048732 gland development 0.0220866413610439 436 12 3 0.25 0.00688073394495413
GO:BP GO:0002709 regulation of T cell mediated immunity 0.0220866413610439 74 67 3 0.0447761194029851 0.0405405405405405
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 0.0220866413610439 167 30 3 0.1 0.0179640718562874
GO:BP GO:0001910 regulation of leukocyte mediated cytotoxicity 0.0220866413610439 74 67 3 0.0447761194029851 0.0405405405405405
GO:BP GO:0055094 response to lipoprotein particle 0.0221878553604683 35 144 3 0.0208333333333333 0.0857142857142857
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.0221878553604683 1477 125 20 0.16 0.01354096140826
GO:BP GO:0031623 receptor internalization 0.0221878553604683 116 90 4 0.0444444444444444 0.0344827586206897
GO:BP GO:0010810 regulation of cell-substrate adhesion 0.0221878553604683 222 113 6 0.0530973451327434 0.027027027027027
GO:BP GO:0002705 positive regulation of leukocyte mediated immunity 0.0222349289599301 122 86 4 0.0465116279069767 0.0327868852459016
GO:BP GO:0007010 cytoskeleton organization 0.0227066355454099 1423 139 21 0.151079136690647 0.0147575544624034
GO:BP GO:0044267 cellular protein metabolic process 0.0227066355454099 5229 128 52 0.40625 0.00994454006502199
GO:BP GO:0045184 establishment of protein localization 0.0232394381023778 2035 145 28 0.193103448275862 0.0137592137592138
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.0232394381023778 366 70 6 0.0857142857142857 0.0163934426229508
GO:BP GO:0045601 regulation of endothelial cell differentiation 0.0232394381023778 50 103 3 0.029126213592233 0.06
GO:BP GO:0071402 cellular response to lipoprotein particle stimulus 0.0232976082244071 36 144 3 0.0208333333333333 0.0833333333333333
GO:BP GO:0002703 regulation of leukocyte mediated immunity 0.0235111918598069 205 86 5 0.0581395348837209 0.024390243902439
GO:BP GO:0061564 axon development 0.0238266085260623 523 123 10 0.0813008130081301 0.0191204588910134
GO:BP GO:0042981 regulation of apoptotic process 0.0238584019880661 1549 146 23 0.157534246575342 0.0148482892188509
GO:BP GO:0002755 MyD88-dependent toll-like receptor signaling pathway 0.0238584019880661 37 143 3 0.020979020979021 0.0810810810810811
GO:BP GO:1903053 regulation of extracellular matrix organization 0.0240539337387082 47 113 3 0.0265486725663717 0.0638297872340425
GO:BP GO:0070169 positive regulation of biomineral tissue development 0.0240539337387082 47 113 3 0.0265486725663717 0.0638297872340425
GO:BP GO:0001819 positive regulation of cytokine production 0.0241693199643339 452 143 10 0.0699300699300699 0.0221238938053097
GO:BP GO:0043066 negative regulation of apoptotic process 0.0241693199643339 921 39 7 0.179487179487179 0.00760043431053203
GO:BP GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 0.0243292455126318 40 134 3 0.0223880597014925 0.075
GO:BP GO:0044085 cellular component biogenesis 0.0243725477005659 3257 124 35 0.282258064516129 0.0107460853546208
GO:BP GO:0007568 aging 0.0243725477005659 329 34 4 0.117647058823529 0.0121580547112462
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.0246862902959151 3483 129 38 0.294573643410853 0.0109101349411427
GO:BP GO:0110151 positive regulation of biomineralization 0.0249100870340997 48 113 3 0.0265486725663717 0.0625
GO:BP GO:0002819 regulation of adaptive immune response 0.025258987513545 167 67 4 0.0597014925373134 0.0239520958083832
GO:BP GO:0030522 intracellular receptor signaling pathway 0.0253263415582793 284 124 7 0.0564516129032258 0.0246478873239437
GO:BP GO:0050900 leukocyte migration 0.0256741601817556 511 70 7 0.1 0.0136986301369863
GO:BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 0.0256741601817556 185 143 6 0.041958041958042 0.0324324324324324
GO:BP GO:0045778 positive regulation of ossification 0.0256741601817556 49 113 3 0.0265486725663717 0.0612244897959184
GO:BP GO:0010628 positive regulation of gene expression 0.0259676649274988 1160 129 17 0.131782945736434 0.0146551724137931
GO:BP GO:0002699 positive regulation of immune effector process 0.0260026112840285 215 86 5 0.0581395348837209 0.0232558139534884
GO:BP GO:0043069 negative regulation of programmed cell death 0.0260733489526511 943 39 7 0.179487179487179 0.00742311770943796
GO:BP GO:0071260 cellular response to mechanical stimulus 0.0264730166642542 80 143 4 0.027972027972028 0.05
GO:BP GO:0046942 carboxylic acid transport 0.0271069517272713 294 64 5 0.078125 0.0170068027210884
GO:BP GO:1903076 regulation of protein localization to plasma membrane 0.0273226473499074 105 110 4 0.0363636363636364 0.0380952380952381
GO:BP GO:0031279 regulation of cyclase activity 0.0275691545947658 47 122 3 0.0245901639344262 0.0638297872340425
GO:BP GO:0045861 negative regulation of proteolysis 0.0278191753601592 359 33 4 0.121212121212121 0.011142061281337
GO:BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.027998180359011 217 27 3 0.111111111111111 0.0138248847926267
GO:BP GO:1903827 regulation of cellular protein localization 0.0287235894317739 572 137 11 0.0802919708029197 0.0192307692307692
GO:BP GO:2000145 regulation of cell motility 0.0292564697141092 1061 143 17 0.118881118881119 0.0160226201696513
GO:BP GO:0002757 immune response-activating signal transduction 0.0293120190228486 477 13 3 0.230769230769231 0.00628930817610063
GO:BP GO:0002429 immune response-activating cell surface receptor signaling pathway 0.0293120190228486 477 13 3 0.230769230769231 0.00628930817610063
GO:BP GO:0015711 organic anion transport 0.0294146854753415 386 72 6 0.0833333333333333 0.0155440414507772
GO:BP GO:0051223 regulation of protein transport 0.0294146854753415 586 80 8 0.1 0.0136518771331058
GO:BP GO:0015718 monocarboxylic acid transport 0.0303428002750248 189 64 4 0.0625 0.0211640211640212
GO:BP GO:0002576 platelet degranulation 0.030592107316237 126 48 3 0.0625 0.0238095238095238
GO:BP GO:0007179 transforming growth factor beta receptor signaling pathway 0.0310409529133692 206 136 6 0.0441176470588235 0.029126213592233
GO:BP GO:0042886 amide transport 0.0310409529133692 2007 138 26 0.188405797101449 0.012954658694569
GO:BP GO:0000904 cell morphogenesis involved in differentiation 0.0316101567822933 749 78 9 0.115384615384615 0.0120160213618158
GO:BP GO:0051247 positive regulation of protein metabolic process 0.0317018834223439 1564 32 8 0.25 0.0051150895140665
GO:BP GO:0031325 positive regulation of cellular metabolic process 0.0317018834223439 3274 113 32 0.283185840707965 0.00977397678680513
GO:BP GO:0010941 regulation of cell death 0.0317018834223439 1720 62 13 0.209677419354839 0.00755813953488372
GO:BP GO:0006811 ion transport 0.0317018834223439 3661 90 29 0.322222222222222 0.00792133296913412
GO:BP GO:0031341 regulation of cell killing 0.0319878251910167 93 67 3 0.0447761194029851 0.032258064516129
GO:BP GO:0007005 mitochondrion organization 0.0320132668253726 561 104 9 0.0865384615384615 0.0160427807486631
GO:BP GO:0051058 negative regulation of small GTPase mediated signal transduction 0.032118953775394 57 110 3 0.0272727272727273 0.0526315789473684
GO:BP GO:0043085 positive regulation of catalytic activity 0.0322630225861024 1418 128 19 0.1484375 0.0133991537376587
GO:BP GO:0051098 regulation of binding 0.0322889257664088 365 131 8 0.0610687022900763 0.0219178082191781
GO:BP GO:0019222 regulation of metabolic process 0.0323701979254281 7148 60 34 0.566666666666667 0.00475657526580862
GO:BP GO:1903426 regulation of reactive oxygen species biosynthetic process 0.0325945744286273 111 113 4 0.0353982300884956 0.036036036036036
GO:BP GO:0071705 nitrogen compound transport 0.0326775731505918 2322 80 19 0.2375 0.00818260120585702
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 0.0326989339031931 512 13 3 0.230769230769231 0.005859375
GO:BP GO:0043269 regulation of ion transport 0.032887329805489 1379 95 15 0.157894736842105 0.0108774474256708
GO:BP GO:0002761 regulation of myeloid leukocyte differentiation 0.032887329805489 123 52 3 0.0576923076923077 0.024390243902439
GO:BP GO:0002764 immune response-regulating signaling pathway 0.032887329805489 515 13 3 0.230769230769231 0.0058252427184466
GO:BP GO:0071222 cellular response to lipopolysaccharide 0.0328913128750206 200 144 6 0.0416666666666667 0.03
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 0.0328913128750206 240 27 3 0.111111111111111 0.0125
GO:BP GO:0051258 protein polymerization 0.0330688863815443 305 95 6 0.0631578947368421 0.019672131147541
GO:BP GO:0006575 cellular modified amino acid metabolic process 0.0330688863815443 199 64 4 0.0625 0.0201005025125628
GO:BP GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 0.0330688863815443 52 124 3 0.0241935483870968 0.0576923076923077
GO:BP GO:0032648 regulation of interferon-beta production 0.0330688863815443 52 124 3 0.0241935483870968 0.0576923076923077
GO:BP GO:0016049 cell growth 0.0330688863815443 495 78 7 0.0897435897435897 0.0141414141414141
GO:BP GO:0044092 negative regulation of molecular function 0.0339551783900615 1219 33 7 0.212121212121212 0.00574241181296144
GO:BP GO:0043330 response to exogenous dsRNA 0.0341571111156678 50 131 3 0.0229007633587786 0.06
GO:BP GO:0002456 T cell mediated immunity 0.0344671077014114 98 67 3 0.0447761194029851 0.0306122448979592
GO:BP GO:0044706 multi-multicellular organism process 0.0344671077014114 227 129 6 0.0465116279069767 0.026431718061674
GO:BP GO:0031323 regulation of cellular metabolic process 0.0345075020032628 6269 42 23 0.547619047619048 0.00366884670601372
GO:BP GO:0090087 regulation of peptide transport 0.0349255654928622 618 80 8 0.1 0.0129449838187702
GO:BP GO:0071772 response to BMP 0.0351497102993203 171 122 5 0.040983606557377 0.0292397660818713
GO:BP GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 0.0351497102993203 50 134 3 0.0223880597014925 0.06
GO:BP GO:0009725 response to hormone 0.0351497102993203 921 8 3 0.375 0.00325732899022801
GO:BP GO:0032608 interferon-beta production 0.0351497102993203 54 124 3 0.0241935483870968 0.0555555555555556
GO:BP GO:0031346 positive regulation of cell projection organization 0.0351497102993203 359 137 8 0.0583941605839416 0.0222841225626741
GO:BP GO:0071773 cellular response to BMP stimulus 0.0351497102993203 171 122 5 0.040983606557377 0.0292397660818713
GO:BP GO:0019538 protein metabolic process 0.0351497102993203 5808 128 55 0.4296875 0.00946969696969697
GO:BP GO:2000026 regulation of multicellular organismal development 0.0351497102993203 1447 146 21 0.143835616438356 0.0145127850725639
GO:BP GO:0010243 response to organonitrogen compound 0.0351860684758881 1085 145 17 0.117241379310345 0.015668202764977
GO:BP GO:0060548 negative regulation of cell death 0.0352586293502945 1038 39 7 0.179487179487179 0.00674373795761079
GO:BP GO:0035148 tube formation 0.0356547793663545 152 87 4 0.0459770114942529 0.0263157894736842
GO:BP GO:0010883 regulation of lipid storage 0.0356997632267085 56 121 3 0.0247933884297521 0.0535714285714286
GO:BP GO:0040012 regulation of locomotion 0.0356997632267085 1104 143 17 0.118881118881119 0.0153985507246377
GO:BP GO:0022411 cellular component disassembly 0.0356997632267085 571 53 6 0.113207547169811 0.010507880910683
GO:BP GO:0051130 positive regulation of cellular component organization 0.0356997632267085 1153 137 17 0.124087591240876 0.0147441457068517
GO:BP GO:0009100 glycoprotein metabolic process 0.0356997632267085 424 117 8 0.0683760683760684 0.0188679245283019
GO:BP GO:0009617 response to bacterium 0.0360872103275054 743 144 13 0.0902777777777778 0.0174966352624495
GO:BP GO:0061614 pri-miRNA transcription by RNA polymerase II 0.0360872103275054 51 134 3 0.0223880597014925 0.0588235294117647
GO:BP GO:0001843 neural tube closure 0.036132109449339 91 75 3 0.04 0.032967032967033
GO:BP GO:0042493 response to drug 0.0361630020993691 396 54 5 0.0925925925925926 0.0126262626262626
GO:BP GO:0043068 positive regulation of programmed cell death 0.0362886447932624 621 134 11 0.082089552238806 0.0177133655394525
GO:BP GO:0060606 tube closure 0.0368373868261968 92 75 3 0.04 0.0326086956521739
GO:BP GO:1903078 positive regulation of protein localization to plasma membrane 0.0369829885091844 63 110 3 0.0272727272727273 0.0476190476190476
GO:BP GO:0090559 regulation of membrane permeability 0.0370626708493086 95 73 3 0.0410958904109589 0.0315789473684211
GO:BP GO:0009267 cellular response to starvation 0.037375033717999 160 134 5 0.0373134328358209 0.03125
GO:BP GO:0051493 regulation of cytoskeleton organization 0.0374060191091654 531 136 10 0.0735294117647059 0.0188323917137476
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.0374060191091654 236 30 3 0.1 0.0127118644067797
GO:BP GO:0009790 embryo development 0.0374060191091654 1035 129 15 0.116279069767442 0.0144927536231884
GO:BP GO:0002253 activation of immune response 0.0376269255476864 568 13 3 0.230769230769231 0.00528169014084507
GO:BP GO:0019216 regulation of lipid metabolic process 0.0376269255476864 419 146 9 0.0616438356164384 0.0214797136038186
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.0378247410351233 3083 113 30 0.265486725663717 0.00973078170613039
GO:BP GO:0048856 anatomical structure development 0.0380297199868876 6106 123 55 0.447154471544715 0.00900753357353423
GO:BP GO:0007411 axon guidance 0.0382200407464244 283 77 5 0.0649350649350649 0.0176678445229682
GO:BP GO:0015833 peptide transport 0.0384700434934542 1971 145 26 0.179310344827586 0.0131912734652461
GO:BP GO:0097485 neuron projection guidance 0.0385279011070202 284 77 5 0.0649350649350649 0.0176056338028169
GO:BP GO:0061028 establishment of endothelial barrier 0.0385279011070202 50 143 3 0.020979020979021 0.06
GO:BP GO:2000649 regulation of sodium ion transmembrane transporter activity 0.0385279011070202 53 135 3 0.0222222222222222 0.0566037735849057
GO:BP GO:0060284 regulation of cell development 0.0385279011070202 502 123 9 0.0731707317073171 0.0179282868525896
GO:BP GO:0070482 response to oxygen levels 0.0385279011070202 408 54 5 0.0925925925925926 0.0122549019607843
GO:BP GO:0001909 leukocyte mediated cytotoxicity 0.0385640725314259 107 67 3 0.0447761194029851 0.0280373831775701
GO:BP GO:0051017 actin filament bundle assembly 0.0386296923562527 161 136 5 0.0367647058823529 0.031055900621118
GO:BP GO:0071219 cellular response to molecule of bacterial origin 0.0386296923562527 214 144 6 0.0416666666666667 0.0280373831775701
GO:BP GO:0006897 endocytosis 0.0386296923562527 696 122 11 0.0901639344262295 0.0158045977011494
GO:BP GO:0044087 regulation of cellular component biogenesis 0.0388204808102817 990 136 15 0.110294117647059 0.0151515151515152
GO:BP GO:0030278 regulation of ossification 0.0388656647573296 115 122 4 0.0327868852459016 0.0347826086956522
GO:BP GO:0014020 primary neural tube formation 0.0388656647573296 97 75 3 0.04 0.0309278350515464
GO:BP GO:0030048 actin filament-based movement 0.0388656647573296 152 92 4 0.0434782608695652 0.0263157894736842
GO:BP GO:0050778 positive regulation of immune response 0.0389574255775705 753 69 8 0.115942028985507 0.0106241699867198
GO:BP GO:1903829 positive regulation of cellular protein localization 0.0389631882220608 303 135 7 0.0518518518518519 0.0231023102310231
GO:BP GO:0009612 response to mechanical stimulus 0.0390167659901771 218 143 6 0.041958041958042 0.0275229357798165
GO:BP GO:0097305 response to alcohol 0.039402998462189 255 123 6 0.0487804878048781 0.0235294117647059
GO:BP GO:0061572 actin filament bundle organization 0.0394629163025842 164 136 5 0.0367647058823529 0.0304878048780488
GO:BP GO:0061919 process utilizing autophagic mechanism 0.0399245403622808 543 42 5 0.119047619047619 0.00920810313075507
GO:BP GO:0006914 autophagy 0.0399245403622808 543 42 5 0.119047619047619 0.00920810313075507
GO:BP GO:0031669 cellular response to nutrient levels 0.0401265961561317 219 144 6 0.0416666666666667 0.0273972602739726
GO:BP GO:0050776 regulation of immune response 0.0402644309706287 996 124 14 0.112903225806452 0.0140562248995984
GO:BP GO:0030888 regulation of B cell proliferation 0.0403775676271156 63 119 3 0.0252100840336134 0.0476190476190476
GO:BP GO:0034613 cellular protein localization 0.0413220565801947 2014 123 23 0.186991869918699 0.0114200595829196
GO:BP GO:0051270 regulation of cellular component movement 0.041486064189487 1141 143 17 0.118881118881119 0.0148992112182296
GO:BP GO:0048640 negative regulation of developmental growth 0.0415272428041703 112 68 3 0.0441176470588235 0.0267857142857143
GO:BP GO:0061912 selective autophagy 0.0423589175049857 63 122 3 0.0245901639344262 0.0476190476190476
GO:BP GO:0048729 tissue morphogenesis 0.0424648210203819 667 113 10 0.0884955752212389 0.0149925037481259
GO:BP GO:0040008 regulation of growth 0.0424653012391915 681 78 8 0.102564102564103 0.0117474302496329
GO:BP GO:1904377 positive regulation of protein localization to cell periphery 0.0424653012391915 70 110 3 0.0272727272727273 0.0428571428571429
GO:BP GO:0070727 cellular macromolecule localization 0.0429792071436324 2024 123 23 0.186991869918699 0.0113636363636364
GO:BP GO:0034446 substrate adhesion-dependent cell spreading 0.0436329832436352 109 136 4 0.0294117647058824 0.036697247706422
GO:BP GO:0048869 cellular developmental process 0.0439708744374241 4428 82 30 0.365853658536585 0.00677506775067751
GO:BP GO:0015031 protein transport 0.0440918321932348 1929 80 16 0.2 0.00829445308449974
GO:BP GO:0001841 neural tube formation 0.0441860880215957 105 75 3 0.04 0.0285714285714286
GO:BP GO:0007266 Rho protein signal transduction 0.0444046876786858 136 110 4 0.0363636363636364 0.0294117647058824
GO:BP GO:0031667 response to nutrient levels 0.0448654545565138 482 17 3 0.176470588235294 0.00622406639004149
GO:BP GO:0072331 signal transduction by p53 class mediator 0.0449238961715703 268 30 3 0.1 0.0111940298507463
GO:BP GO:0030163 protein catabolic process 0.0450494344756001 974 56 8 0.142857142857143 0.0082135523613963
GO:BP GO:0035239 tube morphogenesis 0.0451112188197852 950 146 15 0.102739726027397 0.0157894736842105
GO:BP GO:0031663 lipopolysaccharide-mediated signaling pathway 0.0452955309210627 56 143 3 0.020979020979021 0.0535714285714286
GO:BP GO:0033554 cellular response to stress 0.0452955309210627 2111 17 6 0.352941176470588 0.00284225485551871
GO:BP GO:0051346 negative regulation of hydrolase activity 0.045843975810193 470 33 4 0.121212121212121 0.00851063829787234
GO:BP GO:0051050 positive regulation of transport 0.046051393930186 923 137 14 0.102189781021898 0.0151679306608884
GO:BP GO:0003170 heart valve development 0.0461733770522839 63 129 3 0.0232558139534884 0.0476190476190476
GO:BP GO:0032990 cell part morphogenesis 0.0462021268344544 699 78 8 0.102564102564103 0.011444921316166
GO:BP GO:0009101 glycoprotein biosynthetic process 0.046276917861147 347 69 5 0.072463768115942 0.0144092219020173
GO:BP GO:0061041 regulation of wound healing 0.0463443742515845 136 113 4 0.0353982300884956 0.0294117647058824
GO:BP GO:0001655 urogenital system development 0.0463443742515845 337 129 7 0.0542635658914729 0.0207715133531157
GO:BP GO:0034332 adherens junction organization 0.0467197159696707 67 123 3 0.024390243902439 0.0447761194029851
GO:BP GO:0009892 negative regulation of metabolic process 0.0479381547118829 3479 21 9 0.428571428571429 0.00258695027306697
GO:BP GO:0072657 protein localization to membrane 0.0479381547118829 665 135 11 0.0814814814814815 0.0165413533834586
GO:BP GO:0048513 animal organ development 0.0479381547118829 3672 8 5 0.625 0.00136165577342048
GO:BP GO:0001707 mesoderm formation 0.0481906502061647 74 113 3 0.0265486725663717 0.0405405405405405
GO:BP GO:1901700 response to oxygen-containing compound 0.0482058618943565 1739 145 23 0.158620689655172 0.0132259919493962
GO:BP GO:0060135 maternal process involved in female pregnancy 0.0483279165493457 65 129 3 0.0232558139534884 0.0461538461538462
GO:BP GO:0006892 post-Golgi vesicle-mediated transport 0.0487756902505729 108 78 3 0.0384615384615385 0.0277777777777778
GO:BP GO:0009991 response to extracellular stimulus 0.0487942846135416 512 17 3 0.176470588235294 0.005859375
GO:BP GO:1902305 regulation of sodium ion transmembrane transport 0.0491548764730454 63 135 3 0.0222222222222222 0.0476190476190476
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 0.0492869085386501 2518 33 10 0.303030303030303 0.0039714058776807
GO:BP GO:0045685 regulation of glial cell differentiation 0.0498819273770141 72 119 3 0.0252100840336134 0.0416666666666667
GO:CC GO:0005576 extracellular region 8.1146505107309e-16 4567 79 56 0.708860759493671 0.0122618786949858
GO:CC GO:0070062 extracellular exosome 4.1025669887065e-15 2176 73 38 0.520547945205479 0.0174632352941176
GO:CC GO:0031982 vesicle 5.75293537074772e-15 4055 92 57 0.619565217391304 0.0140567200986437
GO:CC GO:0043230 extracellular organelle 6.18058318180341e-15 2263 73 38 0.520547945205479 0.0167918692001768
GO:CC GO:1903561 extracellular vesicle 6.18058318180341e-15 2261 73 38 0.520547945205479 0.0168067226890756
GO:CC GO:0005615 extracellular space 1.88471959601952e-14 3594 79 48 0.607594936708861 0.013355592654424
GO:CC GO:0016020 membrane 8.10910098333976e-09 9838 123 98 0.796747967479675 0.0099613742630616
GO:CC GO:0071944 cell periphery 1.25031519218231e-08 6169 125 75 0.6 0.0121575620035662
GO:CC GO:0070161 anchoring junction 2.31093522131001e-08 836 141 26 0.184397163120567 0.0311004784688995
GO:CC GO:0005737 cytoplasm 4.42434150881117e-08 11911 145 124 0.855172413793103 0.0104105448744858
GO:CC GO:0012505 endomembrane system 4.42434150881117e-08 4640 145 69 0.475862068965517 0.0148706896551724
GO:CC GO:0005886 plasma membrane 1.19516078080419e-07 5681 125 69 0.552 0.0121457489878543
GO:CC GO:0097708 intracellular vesicle 2.02794527973244e-07 2428 145 45 0.310344827586207 0.0185337726523888
GO:CC GO:0031410 cytoplasmic vesicle 2.02794527973244e-07 2424 145 45 0.310344827586207 0.0185643564356436
GO:CC GO:0043227 membrane-bounded organelle 2.97584063000647e-07 12858 63 61 0.968253968253968 0.00474412816923316
GO:CC GO:0098590 plasma membrane region 5.24148478668655e-07 1240 123 27 0.219512195121951 0.0217741935483871
GO:CC GO:0030055 cell-substrate junction 2.98799269070563e-06 427 141 16 0.113475177304965 0.0374707259953162
GO:CC GO:0042581 specific granule 5.20671183249446e-06 158 137 10 0.072992700729927 0.0632911392405063
GO:CC GO:0016324 apical plasma membrane 9.20762431724349e-06 361 100 12 0.12 0.0332409972299169
GO:CC GO:0043296 apical junction complex 9.20762431724349e-06 145 123 9 0.0731707317073171 0.0620689655172414
GO:CC GO:0005911 cell-cell junction 1.03847932512732e-05 494 136 16 0.117647058823529 0.0323886639676113
GO:CC GO:0005925 focal adhesion 1.07900336637807e-05 420 141 15 0.106382978723404 0.0357142857142857
GO:CC GO:0031974 membrane-enclosed lumen 1.3313376868632e-05 5565 60 36 0.6 0.00646900269541779
GO:CC GO:0043233 organelle lumen 1.3313376868632e-05 5565 60 36 0.6 0.00646900269541779
GO:CC GO:0062023 collagen-containing extracellular matrix 1.5331830198802e-05 421 146 15 0.102739726027397 0.0356294536817102
GO:CC GO:0043226 organelle 2.17681594760171e-05 14008 63 61 0.968253968253968 0.00435465448315248
GO:CC GO:0070013 intracellular organelle lumen 2.89634504259324e-05 5402 56 33 0.589285714285714 0.006108848574602
GO:CC GO:0045177 apical part of cell 4.19958262892273e-05 431 100 12 0.12 0.0278422273781903
GO:CC GO:0030054 cell junction 4.3028833917627e-05 2105 123 32 0.260162601626016 0.0152019002375297
GO:CC GO:0030141 secretory granule 4.96087889502806e-05 851 63 13 0.206349206349206 0.0152761457109283
GO:CC GO:0015629 actin cytoskeleton 5.65869772253956e-05 513 136 15 0.110294117647059 0.0292397660818713
GO:CC GO:0098588 bounding membrane of organelle 5.65869772253956e-05 2158 145 36 0.248275862068966 0.0166821130676552
GO:CC GO:0035577 azurophil granule membrane 5.76365099979926e-05 57 144 6 0.0416666666666667 0.105263157894737
GO:CC GO:0048471 perinuclear region of cytoplasm 5.88614841702232e-05 735 135 18 0.133333333333333 0.0244897959183673
GO:CC GO:0030312 external encapsulating structure 8.41949022683478e-05 563 146 16 0.10958904109589 0.0284191829484902
GO:CC GO:0031012 extracellular matrix 8.41949022683478e-05 562 146 16 0.10958904109589 0.0284697508896797
GO:CC GO:0043256 laminin complex 0.000155533278824478 12 77 3 0.038961038961039 0.25
GO:CC GO:0005829 cytosol 0.000200196113001712 5303 136 61 0.448529411764706 0.011502922873845
GO:CC GO:0005794 Golgi apparatus 0.00022264181027794 1623 141 28 0.198581560283688 0.0172520024645718
GO:CC GO:0005915 zonula adherens 0.000226760501818721 9 123 3 0.024390243902439 0.333333333333333
GO:CC GO:0099503 secretory vesicle 0.000253143617523976 1020 63 13 0.206349206349206 0.0127450980392157
GO:CC GO:0005903 brush border 0.000300752847135652 107 106 6 0.0566037735849057 0.0560747663551402
GO:CC GO:1904724 tertiary granule lumen 0.000322370191945873 55 63 4 0.0634920634920635 0.0727272727272727
GO:CC GO:0035580 specific granule lumen 0.000342353130984603 61 58 4 0.0689655172413793 0.0655737704918033
GO:CC GO:0016328 lateral plasma membrane 0.000379412400896902 68 107 5 0.0467289719626168 0.0735294117647059
GO:CC GO:0030667 secretory granule membrane 0.000521834560302341 303 62 7 0.112903225806452 0.0231023102310231
GO:CC GO:0031090 organelle membrane 0.000747705263119477 3612 145 47 0.324137931034483 0.0130121816168328
GO:CC GO:0005604 basement membrane 0.0007489954637799 97 141 6 0.0425531914893617 0.0618556701030928
GO:CC GO:0005730 nucleolus 0.000786861349773732 955 56 11 0.196428571428571 0.0115183246073298
GO:CC GO:0005923 bicellular tight junction 0.000869435048008188 123 115 6 0.0521739130434783 0.0487804878048781
GO:CC GO:0005912 adherens junction 0.00110651441371604 173 123 7 0.0569105691056911 0.0404624277456647
GO:CC GO:0034364 high-density lipoprotein particle 0.00110651441371604 29 66 3 0.0454545454545455 0.103448275862069
GO:CC GO:0070160 tight junction 0.00115991047526568 131 115 6 0.0521739130434783 0.0458015267175573
GO:CC GO:0005773 vacuole 0.00120093596703711 810 145 17 0.117241379310345 0.0209876543209877
GO:CC GO:0070820 tertiary granule 0.00126355635613516 163 33 4 0.121212121212121 0.0245398773006135
GO:CC GO:0005766 primary lysosome 0.00126355635613516 154 144 7 0.0486111111111111 0.0454545454545455
GO:CC GO:0098852 lytic vacuole membrane 0.00126355635613516 383 145 11 0.0758620689655172 0.0287206266318538
GO:CC GO:0042582 azurophil granule 0.00126355635613516 154 144 7 0.0486111111111111 0.0454545454545455
GO:CC GO:0005765 lysosomal membrane 0.00126355635613516 383 145 11 0.0758620689655172 0.0287206266318538
GO:CC GO:0005622 intracellular anatomical structure 0.0013359720185105 14790 145 130 0.896551724137931 0.00878972278566599
GO:CC GO:0016327 apicolateral plasma membrane 0.00167397133187512 22 107 3 0.0280373831775701 0.136363636363636
GO:CC GO:0005938 cell cortex 0.00178025162227906 311 77 7 0.0909090909090909 0.022508038585209
GO:CC GO:1904813 ficolin-1-rich granule lumen 0.00182575591191855 124 88 5 0.0568181818181818 0.0403225806451613
GO:CC GO:0098862 cluster of actin-based cell projections 0.00191916875021485 162 106 6 0.0566037735849057 0.037037037037037
GO:CC GO:0034358 plasma lipoprotein particle 0.0019388143393592 38 66 3 0.0454545454545455 0.0789473684210526
GO:CC GO:1990777 lipoprotein particle 0.0019388143393592 38 66 3 0.0454545454545455 0.0789473684210526
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.00209947535659591 11296 62 50 0.806451612903226 0.00442634560906516
GO:CC GO:0031253 cell projection membrane 0.0021588450699068 343 121 9 0.0743801652892562 0.0262390670553936
GO:CC GO:0005764 lysosome 0.00217437966610147 712 145 15 0.103448275862069 0.0210674157303371
GO:CC GO:0000323 lytic vacuole 0.00217437966610147 712 145 15 0.103448275862069 0.0210674157303371
GO:CC GO:0009986 cell surface 0.00217437966610147 899 69 11 0.159420289855072 0.0122358175750834
GO:CC GO:0032994 protein-lipid complex 0.00223128891749986 41 66 3 0.0454545454545455 0.0731707317073171
GO:CC GO:0016459 myosin complex 0.00223128891749986 57 115 4 0.0347826086956522 0.0701754385964912
GO:CC GO:0031226 intrinsic component of plasma membrane 0.00228283907568227 1726 119 23 0.19327731092437 0.0133256083429896
GO:CC GO:0035579 specific granule membrane 0.00266867829100755 90 137 5 0.0364963503649635 0.0555555555555556
GO:CC GO:0005887 integral component of plasma membrane 0.00284873882040101 1645 119 22 0.184873949579832 0.0133738601823708
GO:CC GO:0005774 vacuolar membrane 0.00307651207024996 441 145 11 0.0758620689655172 0.0249433106575964
GO:CC GO:0098857 membrane microdomain 0.00333063001468487 335 135 9 0.0666666666666667 0.026865671641791
GO:CC GO:0045121 membrane raft 0.00333063001468487 335 135 9 0.0666666666666667 0.026865671641791
GO:CC GO:0034774 secretory granule lumen 0.00333063001468487 320 63 6 0.0952380952380952 0.01875
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.00349498237331995 324 63 6 0.0952380952380952 0.0185185185185185
GO:CC GO:0031983 vesicle lumen 0.00356692272549766 326 63 6 0.0952380952380952 0.0184049079754601
GO:CC GO:0012506 vesicle membrane 0.00377546456699875 800 84 11 0.130952380952381 0.01375
GO:CC GO:0009925 basal plasma membrane 0.00387494748502415 247 116 7 0.0603448275862069 0.0283400809716599
GO:CC GO:0001726 ruffle 0.00397564273260046 179 78 5 0.0641025641025641 0.0279329608938547
GO:CC GO:0031981 nuclear lumen 0.00457297735248557 4444 56 24 0.428571428571429 0.0054005400540054
GO:CC GO:0014069 postsynaptic density 0.00474223154449955 334 90 7 0.0777777777777778 0.0209580838323353
GO:CC GO:0031252 cell leading edge 0.00494983892373776 422 139 10 0.0719424460431655 0.023696682464455
GO:CC GO:0032279 asymmetric synapse 0.0051455418541499 340 90 7 0.0777777777777778 0.0205882352941176
GO:CC GO:0045178 basal part of cell 0.00534412333087232 265 116 7 0.0603448275862069 0.0264150943396226
GO:CC GO:0043229 intracellular organelle 0.00558415447175088 12491 62 52 0.838709677419355 0.00416299735809783
GO:CC GO:0005768 endosome 0.00612578409683575 987 145 17 0.117241379310345 0.0172239108409321
GO:CC GO:0098858 actin-based cell projection 0.00641173804402115 220 145 7 0.0482758620689655 0.0318181818181818
GO:CC GO:0099572 postsynaptic specialization 0.00650521058988999 358 90 7 0.0777777777777778 0.0195530726256983
GO:CC GO:0101002 ficolin-1-rich granule 0.00681322267206699 184 88 5 0.0568181818181818 0.0271739130434783
GO:CC GO:0098984 neuron to neuron synapse 0.00723222787994884 366 90 7 0.0777777777777778 0.0191256830601093
GO:CC GO:0042995 cell projection 0.00723471561999072 2330 123 27 0.219512195121951 0.011587982832618
GO:CC GO:0030139 endocytic vesicle 0.00723471561999072 306 138 8 0.0579710144927536 0.0261437908496732
GO:CC GO:0005788 endoplasmic reticulum lumen 0.00830678181706728 307 34 4 0.117647058823529 0.0130293159609121
GO:CC GO:0042641 actomyosin 0.00876804194188738 77 136 4 0.0294117647058824 0.051948051948052
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.00876804194188738 779 84 10 0.119047619047619 0.0128369704749679
GO:CC GO:0016323 basolateral plasma membrane 0.0093004128778424 222 116 6 0.0517241379310345 0.027027027027027
GO:CC GO:0005811 lipid droplet 0.0113559813718793 95 121 4 0.0330578512396694 0.0421052631578947
GO:CC GO:0000139 Golgi membrane 0.0123970400416277 771 120 12 0.1 0.0155642023346304
GO:CC GO:0030863 cortical cytoskeleton 0.013933228560139 107 57 3 0.0526315789473684 0.0280373831775701
GO:CC GO:0120025 plasma membrane bounded cell projection 0.0142526210020006 2229 123 25 0.203252032520325 0.0112157918349035
GO:CC GO:0005654 nucleoplasm 0.0143430883081011 4102 52 20 0.384615384615385 0.00487567040468064
GO:CC GO:0031225 anchored component of membrane 0.0143717379226505 174 36 3 0.0833333333333333 0.0172413793103448
GO:CC GO:0030016 myofibril 0.0145689924742804 231 88 5 0.0568181818181818 0.0216450216450216
GO:CC GO:0030426 growth cone 0.0153109822939959 187 110 5 0.0454545454545455 0.0267379679144385
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.0157234792706651 5338 58 26 0.448275862068966 0.00487073810415886
GO:CC GO:0043228 non-membrane-bounded organelle 0.0158238574433127 5346 58 26 0.448275862068966 0.00486344930789375
GO:CC GO:0005902 microvillus 0.0164423749803204 91 145 4 0.0275862068965517 0.043956043956044
GO:CC GO:0043292 contractile fiber 0.0164423749803204 240 88 5 0.0568181818181818 0.0208333333333333
GO:CC GO:0030427 site of polarized growth 0.0166951789980884 193 110 5 0.0454545454545455 0.0259067357512953
GO:CC GO:0031256 leading edge membrane 0.0180443843225933 175 78 4 0.0512820512820513 0.0228571428571429
GO:CC GO:0042470 melanosome 0.020398521771778 105 135 4 0.0296296296296296 0.0380952380952381
GO:CC GO:0048770 pigment granule 0.020398521771778 105 135 4 0.0296296296296296 0.0380952380952381
GO:CC GO:0043005 neuron projection 0.0214432267544182 1380 93 14 0.150537634408602 0.0101449275362319
GO:CC GO:0032587 ruffle membrane 0.0215134616202362 96 78 3 0.0384615384615385 0.03125
GO:CC GO:0031224 intrinsic component of membrane 0.0228367221590966 5868 76 34 0.447368421052632 0.00579413769597819
GO:CC GO:0099512 supramolecular fiber 0.0228653630040666 993 91 11 0.120879120879121 0.0110775427995972
GO:CC GO:0099081 supramolecular polymer 0.0238560047301686 1001 91 11 0.120879120879121 0.010989010989011
GO:CC GO:0005776 autophagosome 0.027224141770528 98 86 3 0.0348837209302326 0.0306122448979592
GO:CC GO:0036477 somatodendritic compartment 0.0276013013744522 871 93 10 0.10752688172043 0.0114810562571757
GO:CC GO:0098791 Golgi apparatus subcompartment 0.0276013013744522 885 120 12 0.1 0.0135593220338983
GO:CC GO:0005856 cytoskeleton 0.0276358401226328 2332 139 27 0.194244604316547 0.0115780445969125
GO:CC GO:0044291 cell-cell contact zone 0.0313135489896147 74 123 3 0.024390243902439 0.0405405405405405
GO:CC GO:0043235 receptor complex 0.0318118436028291 522 113 8 0.0707964601769911 0.0153256704980843
GO:CC GO:0030425 dendrite 0.0320860025754629 638 93 8 0.0860215053763441 0.0125391849529781
GO:CC GO:0097447 dendritic tree 0.032454370773645 640 93 8 0.0860215053763441 0.0125
GO:CC GO:0005634 nucleus 0.0324723807606693 7592 60 33 0.55 0.00434668071654373
GO:CC GO:0016605 PML body 0.0331429550549593 102 93 3 0.032258064516129 0.0294117647058824
GO:CC GO:0010008 endosome membrane 0.0355750429537026 505 144 9 0.0625 0.0178217821782178
GO:CC GO:0031984 organelle subcompartment 0.0367306059021392 1773 120 19 0.158333333333333 0.0107163000564016
GO:CC GO:0030017 sarcomere 0.0371560530260779 208 88 4 0.0454545454545455 0.0192307692307692
GO:CC GO:0005783 endoplasmic reticulum 0.0392142317331887 1982 39 9 0.230769230769231 0.00454086781029263
GO:CC GO:0016021 integral component of membrane 0.0398203628098997 5711 76 32 0.421052631578947 0.00560322185256523
GO:CC GO:0005884 actin filament 0.0423714231729538 118 91 3 0.032967032967033 0.0254237288135593
GO:CC GO:0032991 protein-containing complex 0.0467403768022759 5548 9 6 0.666666666666667 0.00108147080028839
GO:CC GO:0030424 axon 0.0477142698848513 660 119 9 0.0756302521008403 0.0136363636363636
GO:MF GO:0050839 cell adhesion molecule binding 4.81196480765474e-09 546 123 22 0.178861788617886 0.0402930402930403
GO:MF GO:0045296 cadherin binding 1.47648560922305e-06 333 123 15 0.121951219512195 0.045045045045045
GO:MF GO:0001730 2'-5'-oligoadenylate synthetase activity 0.000107473188461119 4 99 3 0.0303030303030303 0.75
GO:MF GO:0044877 protein-containing complex binding 0.000166255329527753 1287 58 16 0.275862068965517 0.0124320124320124
GO:MF GO:0003779 actin binding 0.000170292394811607 448 123 14 0.113821138211382 0.03125
GO:MF GO:0042803 protein homodimerization activity 0.000177630390615834 676 73 13 0.178082191780822 0.0192307692307692
GO:MF GO:0005515 protein binding 0.000669366757586313 14767 146 135 0.924657534246575 0.0091420058237963
GO:MF GO:0005102 signaling receptor binding 0.000829994886617342 1672 146 30 0.205479452054795 0.0179425837320574
GO:MF GO:0046983 protein dimerization activity 0.000829994886617342 1069 73 15 0.205479452054795 0.0140318054256314
GO:MF GO:0008092 cytoskeletal protein binding 0.00152859461768443 996 123 19 0.154471544715447 0.0190763052208835
GO:MF GO:0019899 enzyme binding 0.00219183419149397 2074 145 33 0.227586206896552 0.0159112825458052
GO:MF GO:0042802 identical protein binding 0.00219183419149397 2067 146 33 0.226027397260274 0.0159651669085631
GO:MF GO:0005178 integrin binding 0.00905404000900993 147 70 5 0.0714285714285714 0.0340136054421769
GO:MF GO:0031593 polyubiquitin modification-dependent protein binding 0.00905404000900993 52 42 3 0.0714285714285714 0.0576923076923077
GO:MF GO:0008013 beta-catenin binding 0.0143492242910701 87 136 5 0.0367647058823529 0.0574712643678161
GO:MF GO:0001882 nucleoside binding 0.0151067227471855 395 132 10 0.0757575757575758 0.0253164556962025
GO:MF GO:0019900 kinase binding 0.0165475606705257 752 113 13 0.115044247787611 0.0172872340425532
GO:MF GO:0070566 adenylyltransferase activity 0.0166851358818644 33 99 3 0.0303030303030303 0.0909090909090909
GO:MF GO:0003725 double-stranded RNA binding 0.0166851358818644 77 99 4 0.0404040404040404 0.051948051948052
GO:MF GO:0019901 protein kinase binding 0.0166851358818644 673 113 12 0.106194690265487 0.0178306092124814
GO:MF GO:0017111 nucleoside-triphosphatase activity 0.0166851358818644 872 138 16 0.115942028985507 0.018348623853211
GO:MF GO:0005198 structural molecule activity 0.0166851358818644 698 123 13 0.105691056910569 0.0186246418338109
GO:MF GO:0019904 protein domain specific binding 0.0194859229526041 710 125 13 0.104 0.0183098591549296
GO:MF GO:0030295 protein kinase activator activity 0.0217730606587592 85 101 4 0.0396039603960396 0.0470588235294118
GO:MF GO:0016817 hydrolase activity, acting on acid anhydrides 0.0231312914971067 930 138 16 0.115942028985507 0.0172043010752688
GO:MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0231312914971067 930 138 16 0.115942028985507 0.0172043010752688
GO:MF GO:0016462 pyrophosphatase activity 0.0231312914971067 928 138 16 0.115942028985507 0.0172413793103448
GO:MF GO:0019209 kinase activator activity 0.0233656231851719 91 101 4 0.0396039603960396 0.043956043956044
GO:MF GO:0003824 catalytic activity 0.0244064014504395 5896 140 61 0.435714285714286 0.0103459972862958
GO:MF GO:0051427 hormone receptor binding 0.0299074769854867 182 58 4 0.0689655172413793 0.021978021978022
GO:MF GO:0001618 virus receptor activity 0.0320889671829239 76 70 3 0.0428571428571429 0.0394736842105263
GO:MF GO:0005516 calmodulin binding 0.0320889671829239 204 54 4 0.0740740740740741 0.0196078431372549
GO:MF GO:0140272 exogenous protein binding 0.0320889671829239 77 70 3 0.0428571428571429 0.038961038961039
GO:MF GO:0004866 endopeptidase inhibitor activity 0.034613972207454 176 33 3 0.0909090909090909 0.0170454545454545
GO:MF GO:0008022 protein C-terminus binding 0.0347289250433248 202 60 4 0.0666666666666667 0.0198019801980198
GO:MF GO:0019887 protein kinase regulator activity 0.0347289250433248 191 101 5 0.0495049504950495 0.0261780104712042
GO:MF GO:0030414 peptidase inhibitor activity 0.0347289250433248 182 33 3 0.0909090909090909 0.0164835164835165
GO:MF GO:0005200 structural constituent of cytoskeleton 0.0347289250433248 104 56 3 0.0535714285714286 0.0288461538461538
GO:MF GO:0061135 endopeptidase regulator activity 0.0350897421337474 188 33 3 0.0909090909090909 0.0159574468085106
GO:MF GO:0004857 enzyme inhibitor activity 0.0357764516343444 385 33 4 0.121212121212121 0.0103896103896104
GO:MF GO:0016787 hydrolase activity 0.0361291184932423 2615 138 31 0.22463768115942 0.0118546845124283
GO:MF GO:0005525 GTP binding 0.0384799433157546 381 132 8 0.0606060606060606 0.020997375328084
GO:MF GO:0140030 modification-dependent protein binding 0.0384799433157546 160 42 3 0.0714285714285714 0.01875
GO:MF GO:0005201 extracellular matrix structural constituent 0.0384799433157546 171 77 4 0.051948051948052 0.0233918128654971
GO:MF GO:0098772 molecular function regulator 0.0389208556657805 2363 88 20 0.227272727272727 0.00846381718154888
GO:MF GO:0032550 purine ribonucleoside binding 0.0389208556657805 386 132 8 0.0606060606060606 0.0207253886010363
GO:MF GO:0032549 ribonucleoside binding 0.0389628479987265 389 132 8 0.0606060606060606 0.0205655526992288
GO:MF GO:0001883 purine nucleoside binding 0.0389628479987265 389 132 8 0.0606060606060606 0.0205655526992288
GO:MF GO:0019207 kinase regulator activity 0.0399005433590127 221 101 5 0.0495049504950495 0.0226244343891403
GO:MF GO:0061134 peptidase regulator activity 0.0399005433590127 224 33 3 0.0909090909090909 0.0133928571428571
GO:MF GO:0097367 carbohydrate derivative binding 0.0399005433590127 2285 92 20 0.217391304347826 0.0087527352297593
GO:MF GO:0032561 guanyl ribonucleotide binding 0.041206438251322 403 132 8 0.0606060606060606 0.0198511166253102
GO:MF GO:0030234 enzyme regulator activity 0.041206438251322 1248 53 9 0.169811320754717 0.00721153846153846
GO:MF GO:0019001 guanyl nucleotide binding 0.041206438251322 403 132 8 0.0606060606060606 0.0198511166253102
GO:MF GO:0003713 transcription coactivator activity 0.0421457935437874 280 83 5 0.0602409638554217 0.0178571428571429
GO:MF GO:0005518 collagen binding 0.0439353204667359 70 113 3 0.0265486725663717 0.0428571428571429
GO:MF GO:0016772 transferase activity, transferring phosphorus-containing groups 0.0439353204667359 952 47 7 0.148936170212766 0.00735294117647059
GO:MF GO:0008509 anion transmembrane transporter activity 0.0439353204667359 464 72 6 0.0833333333333333 0.0129310344827586
GO:MF GO:0043621 protein self-association 0.0439353204667359 56 143 3 0.020979020979021 0.0535714285714286
GO:MF GO:0003774 motor activity 0.0442825268983993 134 115 4 0.0347826086956522 0.0298507462686567
GO:MF GO:0035257 nuclear hormone receptor binding 0.0482735583367085 148 58 3 0.0517241379310345 0.0202702702702703
HP HP:0032449 Abnormal dermoepidermal hemidesmosome morphology 0.000475667456353766 5 77 4 0.051948051948052 0.8
HP HP:0020117 Hypoplastic dermoepidermal hemidesmosomes 0.000475667456353766 5 77 4 0.051948051948052 0.8
HP HP:0031538 Abnormal dermoepidermal junction morphology 0.000906491201239954 6 77 4 0.051948051948052 0.666666666666667
HP HP:0200097 Oral mucosal blisters 0.000906491201239954 13 77 5 0.0649350649350649 0.384615384615385
HP HP:0003341 Junctional split 0.00129742843450072 7 77 4 0.051948051948052 0.571428571428571
HP HP:0007383 Congenital localized absence of skin 0.00213425492853777 8 77 4 0.051948051948052 0.5
HP HP:0200041 Skin erosion 0.0023601561723389 17 77 5 0.0649350649350649 0.294117647058824
HP HP:0004552 Scarring alopecia of scalp 0.00644950096446545 11 77 4 0.051948051948052 0.363636363636364
HP HP:0010476 Aplasia/Hypoplasia of the bladder 0.00644950096446545 11 77 4 0.051948051948052 0.363636363636364
HP HP:0008682 Renal tubular epithelial necrosis 0.00876860114477192 5 77 3 0.038961038961039 0.6
HP HP:0031446 Erosion of oral mucosa 0.00876860114477192 5 77 3 0.038961038961039 0.6
HP HP:0000999 Pyoderma 0.00876860114477192 5 77 3 0.038961038961039 0.6
HP HP:0032618 Renal necrosis 0.00876860114477192 5 77 3 0.038961038961039 0.6
HP HP:0000096 Glomerular sclerosis 0.0105596014326093 75 110 9 0.0818181818181818 0.12
HP HP:0012227 Urethral stricture 0.0105596014326093 14 77 4 0.051948051948052 0.285714285714286
HP HP:0002043 Esophageal stricture 0.0105596014326093 14 77 4 0.051948051948052 0.285714285714286
HP HP:0001030 Fragile skin 0.0105596014326093 30 110 6 0.0545454545454545 0.2
HP HP:0001955 Unexplained fevers 0.0215044362908465 17 77 4 0.051948051948052 0.235294117647059
HP HP:0001056 Milia 0.0307499539418816 19 77 4 0.051948051948052 0.210526315789474
HP HP:0004057 Mitten deformity 0.0307499539418816 8 77 3 0.038961038961039 0.375
KEGG KEGG:05160 Hepatitis C 0.00201293275997558 157 131 12 0.0916030534351145 0.0764331210191083
KEGG KEGG:05222 Small cell lung cancer 0.003918027222441 92 110 8 0.0727272727272727 0.0869565217391304
KEGG KEGG:05145 Toxoplasmosis 0.0100139398538868 109 143 9 0.0629370629370629 0.0825688073394495
KEGG KEGG:05164 Influenza A 0.0116105484387772 169 143 11 0.0769230769230769 0.0650887573964497
KEGG KEGG:05146 Amoebiasis 0.0177876397991647 101 77 6 0.0779220779220779 0.0594059405940594
KEGG KEGG:04520 Adherens junction 0.0273811130824578 71 123 6 0.0487804878048781 0.0845070422535211
KEGG KEGG:05202 Transcriptional misregulation in cancer 0.0434360510205719 191 21 4 0.19047619047619 0.0209424083769634
MIRNA MIRNA:hsa-miR-146a-5p hsa-miR-146a-5p 0.000604436887823387 200 90 10 0.111111111111111 0.05
REAC REAC:R-HSA-1500931 Cell-Cell communication 2.44413251934526e-06 127 136 13 0.0955882352941176 0.102362204724409
REAC REAC:R-HSA-909733 Interferon alpha/beta signaling 2.44413251934526e-06 66 131 10 0.0763358778625954 0.151515151515152
REAC REAC:R-HSA-913531 Interferon Signaling 1.90297912847877e-05 191 131 14 0.106870229007634 0.0732984293193717
REAC REAC:R-HSA-446728 Cell junction organization 3.54016464250653e-05 91 136 10 0.0735294117647059 0.10989010989011
REAC REAC:R-HSA-446107 Type I hemidesmosome assembly 9.76792839124518e-05 11 77 4 0.051948051948052 0.363636363636364
REAC REAC:R-HSA-168256 Immune System 0.000152689943778848 2139 145 54 0.372413793103448 0.0252454417952314
REAC REAC:R-HSA-168249 Innate Immune System 0.000340113701199626 1073 88 24 0.272727272727273 0.0223671947809879
REAC REAC:R-HSA-877300 Interferon gamma signaling 0.0010267548615549 87 99 7 0.0707070707070707 0.0804597701149425
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 0.0010267548615549 842 134 26 0.194029850746269 0.0308788598574822
REAC REAC:R-HSA-6798695 Neutrophil degranulation 0.00103831759069762 474 63 12 0.19047619047619 0.0253164556962025
REAC REAC:R-HSA-1474244 Extracellular matrix organization 0.00148697918850468 298 33 7 0.212121212121212 0.023489932885906
REAC REAC:R-HSA-3000157 Laminin interactions 0.00195223236813062 30 141 5 0.0354609929078014 0.166666666666667
REAC REAC:R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 0.0020652756927794 78 131 7 0.0534351145038168 0.0897435897435897
REAC REAC:R-HSA-8983711 OAS antiviral response 0.0025255948781413 9 99 3 0.0303030303030303 0.333333333333333
REAC REAC:R-HSA-5083636 Defective GALNT12 causes colorectal cancer 1 (CRCS1) 0.0048642924006526 16 69 3 0.0434782608695652 0.1875
REAC REAC:R-HSA-5083625 Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) 0.0048642924006526 16 69 3 0.0434782608695652 0.1875
REAC REAC:R-HSA-2214320 Anchoring fibril formation 0.00520018728028047 15 77 3 0.038961038961039 0.2
REAC REAC:R-HSA-5083632 Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) 0.00526014707897174 17 69 3 0.0434782608695652 0.176470588235294
REAC REAC:R-HSA-373753 Nephrin family interactions 0.00681955684201423 23 56 3 0.0535714285714286 0.130434782608696
REAC REAC:R-HSA-8874081 MET activates PTK2 signaling 0.00694805127755278 30 110 4 0.0363636363636364 0.133333333333333
REAC REAC:R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 0.0171414421793029 60 31 3 0.0967741935483871 0.05
REAC REAC:R-HSA-8875878 MET promotes cell motility 0.0179644964298821 40 110 4 0.0363636363636364 0.1
REAC REAC:R-HSA-1474228 Degradation of the extracellular matrix 0.0195811221734784 140 33 4 0.121212121212121 0.0285714285714286
REAC REAC:R-HSA-421270 Cell-cell junction organization 0.0195811221734784 64 123 5 0.040650406504065 0.078125
REAC REAC:R-HSA-6806834 Signaling by MET 0.0241709125001422 76 110 5 0.0454545454545455 0.0657894736842105
REAC REAC:R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 0.0241709125001422 17 134 3 0.0223880597014925 0.176470588235294
REAC REAC:R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 0.0303361657854846 126 143 7 0.048951048951049 0.0555555555555556
REAC REAC:R-HSA-1474290 Collagen formation 0.0377880117099479 89 31 3 0.0967741935483871 0.0337078651685393
REAC REAC:R-HSA-9637690 Response of Mtb to phagocytosis 0.0377880117099479 23 122 3 0.0245901639344262 0.130434782608696
REAC REAC:R-HSA-2980736 Peptide hormone metabolism 0.0439590662772977 86 36 3 0.0833333333333333 0.0348837209302326
REAC REAC:R-HSA-5357801 Programmed Cell Death 0.0481855712775943 177 19 3 0.157894736842105 0.0169491525423729
REAC REAC:R-HSA-9635486 Infection with Mycobacterium tuberculosis 0.0481855712775943 27 122 3 0.0245901639344262 0.111111111111111
TF TF:M09957 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN 4.7047186311384e-05 272 138 14 0.101449275362319 0.0514705882352941
TF TF:M07040 Factor: GKLF; motif: NNRRGRRNGNSNNN 0.000142046347050522 12705 144 122 0.847222222222222 0.00960251869342778
TF TF:M07216 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT 0.000169084809834812 440 138 16 0.115942028985507 0.0363636363636364
TF TF:M04014 Factor: IRF3; motif: NNRRAANGGAAACCGAAACYR 0.000464277543768517 278 131 12 0.0916030534351145 0.0431654676258993
TF TF:M09956 Factor: IRF-1; motif: NAAANNGAAASTGAAASNRN 0.000464277543768517 317 138 13 0.0942028985507246 0.0410094637223975
TF TF:M00931_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.000720262305051221 5905 141 70 0.49645390070922 0.0118543607112616
TF TF:M03567_1 Factor: Sp2; motif: NYSGCCCCGCCCCCY; match class: 1 0.000888446282336071 3614 141 50 0.354609929078014 0.0138350857775318
TF TF:M03807_1 Factor: SP2; motif: GNNGGGGGCGGGGSN; match class: 1 0.00125528561530973 4199 142 55 0.387323943661972 0.0130983567516075
TF TF:M11423 Factor: Erm; motif: RSAGGAAGGAAGTN 0.00160650188626963 4841 100 46 0.46 0.00950216897335261
TF TF:M08911_1 Factor: CTCF; motif: NCCRSTAGGGGGCGC; match class: 1 0.00160650188626963 3934 142 52 0.366197183098592 0.0132180986273513
TF TF:M11679 Factor: IRF-7; motif: NCGAAANCGAAANYN 0.00160650188626963 622 143 17 0.118881118881119 0.0273311897106109
TF TF:M01588 Factor: GKLF; motif: GCCMCRCCCNNN 0.00172268543838218 8944 141 91 0.645390070921986 0.0101744186046512
TF TF:M10134 Factor: FPM315; motif: GGGAGGAGGRRGRGGRGGRR 0.00280757674325985 2472 124 34 0.274193548387097 0.0137540453074434
TF TF:M11729 Factor: NF-1C; motif: NTTGGCNNNNTGCCARN 0.00280757674325985 1738 14 8 0.571428571428571 0.0046029919447641
TF TF:M07040_1 Factor: GKLF; motif: NNRRGRRNGNSNNN; match class: 1 0.00280757674325985 8156 142 85 0.598591549295775 0.0104217753800883
TF TF:M00932_1 Factor: Sp1; motif: NNGGGGCGGGGNN; match class: 1 0.00312310855397926 6047 141 68 0.482269503546099 0.0112452455763188
TF TF:M00196_1 Factor: Sp1; motif: NGGGGGCGGGGYN; match class: 1 0.00312310855397926 5919 141 67 0.475177304964539 0.0113194796418314
TF TF:M10094_1 Factor: RelA-p65; motif: NWGGGRATTTCCMN; match class: 1 0.00312310855397926 242 138 10 0.072463768115942 0.0413223140495868
TF TF:M01835_1 Factor: GKLF; motif: CCTCCYN; match class: 1 0.00323133582397291 10142 138 96 0.695652173913043 0.00946558864129363
TF TF:M04020_1 Factor: IRF8; motif: NCGAAACCGAAACT; match class: 1 0.00323133582397291 45 131 5 0.0381679389312977 0.111111111111111
TF TF:M11671 Factor: IRF-5; motif: NCGAAACCGAAACY 0.00323133582397291 389 131 12 0.0916030534351145 0.0308483290488432
TF TF:M08229 Factor: Elk-1:SREBP-2; motif: RTCACGTGACCGGAAGN 0.00323133582397291 9535 20 19 0.95 0.00199265862611432
TF TF:M08887_1 Factor: IRF; motif: NNGAAANTGAAANN; match class: 1 0.00323133582397291 73 138 6 0.0434782608695652 0.0821917808219178
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 0.00323133582397291 6334 141 70 0.49645390070922 0.0110514682664983
TF TF:M09760_1 Factor: DPF2; motif: NYCACYTCCYCNYYCY; match class: 1 0.00342551490249969 2978 117 36 0.307692307692308 0.0120886501007388
TF TF:M12354_1 Factor: ZNF37A; motif: CCYYGGCTCCNTSCCMN; match class: 1 0.00425853400443997 5624 142 64 0.450704225352113 0.0113798008534851
TF TF:M12354 Factor: ZNF37A; motif: CCYYGGCTCCNTSCCMN 0.00425853400443997 10961 137 100 0.72992700729927 0.00912325517744731
TF TF:M00450 Factor: Zic3; motif: NGGGKGGTC 0.00425853400443997 14000 109 96 0.880733944954128 0.00685714285714286
TF TF:M11728 Factor: NF-1C; motif: NTTGGCNNNNTGCCARN 0.00448535688993253 2634 9 7 0.777777777777778 0.00265755504935459
TF TF:M09970_1 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN; match class: 1 0.00448535688993253 3783 141 48 0.340425531914894 0.0126883425852498
TF TF:M07063 Factor: Sp1; motif: GGGGCGGGGC 0.0050314898075789 7696 143 80 0.559440559440559 0.0103950103950104
TF TF:M01100_1 Factor: LRF; motif: GGGGKYNNB; match class: 1 0.0050314898075789 2762 144 39 0.270833333333333 0.0141202027516293
TF TF:M01875 Factor: ER-beta; motif: GTCANASTGRCCYNR 0.0050314898075789 6452 26 19 0.730769230769231 0.00294482331060136
TF TF:M07277 Factor: BTEB2; motif: RGGGNGKGGN 0.0050314898075789 8492 143 86 0.601398601398601 0.0101271785209609
TF TF:M10435 Factor: Sp2; motif: GGGGCGGGG 0.0050314898075789 7696 143 80 0.559440559440559 0.0103950103950104
TF TF:M08662 Factor: AP-2gamma:HES-7; motif: NNCACGYGNNNNNNSCCNNNGGS 0.0050314898075789 1975 143 31 0.216783216783217 0.0156962025316456
TF TF:M07041 Factor: HDAC1; motif: KGCARGGTC 0.0050314898075789 12526 23 23 1 0.00183618074405237
TF TF:M00470 Factor: AP-2gamma; motif: GCCYNNGGS 0.00516751795720106 9422 142 92 0.647887323943662 0.0097643812354065
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.00540153958907977 10357 143 99 0.692307692307692 0.00955875253451772
TF TF:M10072_1 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR; match class: 1 0.00540153958907977 6225 142 68 0.47887323943662 0.0109236947791165
TF TF:M00933_1 Factor: Sp1; motif: CCCCGCCCCN; match class: 1 0.00559696806293263 5166 141 59 0.418439716312057 0.0114208284939992
TF TF:M02018_1 Factor: HTF4; motif: CASCTGB; match class: 1 0.00559696806293263 2796 91 28 0.307692307692308 0.0100143061516452
TF TF:M03831_1 Factor: MRF4; motif: CASCTGC; match class: 1 0.00559696806293263 2796 91 28 0.307692307692308 0.0100143061516452
TF TF:M10080 Factor: STAT2; motif: RRGRAANNGAAACTGAAAN 0.00569954548884054 356 138 11 0.0797101449275362 0.0308988764044944
TF TF:M01865 Factor: BTEB3; motif: BNRNGGGAGGNGT 0.00569954548884054 9899 142 95 0.669014084507042 0.00959692898272553
TF TF:M07602_1 Factor: CP2; motif: NNNNCCAGNCNN; match class: 1 0.00569954548884054 4627 114 46 0.403508771929825 0.00994164685541388
TF TF:M01303 Factor: SP1; motif: GGGGYGGGGNS 0.00569954548884054 7898 143 81 0.566433566433566 0.0102557609521398
TF TF:M00638_1 Factor: HNF4alpha; motif: VTGAACTTTGMMB; match class: 1 0.00569954548884054 258 6 3 0.5 0.0116279069767442
TF TF:M04016 Factor: IRF5; motif: CCGAAACCGAAACY 0.00596546478160716 314 131 10 0.0763358778625954 0.0318471337579618
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.00596546478160716 10281 143 98 0.685314685314685 0.00953214667833868
TF TF:M07430 Factor: SNA; motif: NCACCTGCNN 0.00596546478160716 1750 60 16 0.266666666666667 0.00914285714285714
TF TF:M10071_1 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG; match class: 1 0.00654017262418708 4623 141 54 0.382978723404255 0.0116807268007787
TF TF:M08571_1 Factor: Erm:E2A; motif: CASGTGNNNCGGAAGNN; match class: 1 0.006570497700121 4425 123 47 0.382113821138211 0.0106214689265537
TF TF:M11664_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 0.00688016150979454 140 138 7 0.0507246376811594 0.05
TF TF:M00189_1 Factor: AP-2; motif: MKCCCSCNGGCG; match class: 1 0.0073635365020208 6093 142 66 0.464788732394366 0.0108321024126046
TF TF:M07063_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.0073635365020208 3495 141 44 0.312056737588652 0.0125894134477825
TF TF:M10435_1 Factor: Sp2; motif: GGGGCGGGG; match class: 1 0.0073635365020208 3495 141 44 0.312056737588652 0.0125894134477825
TF TF:M07615 Factor: Sp3; motif: GGGGCGGGGSNN 0.0073635365020208 6807 143 72 0.503496503496504 0.0105773468488321
TF TF:M01588_1 Factor: GKLF; motif: GCCMCRCCCNNN; match class: 1 0.00764781272378688 3962 141 48 0.340425531914894 0.0121150933871782
TF TF:M01857_1 Factor: AP-2alpha; motif: NGCCYSNNGSN; match class: 1 0.00778003161044567 4616 136 52 0.382352941176471 0.011265164644714
TF TF:M01857 Factor: AP-2alpha; motif: NGCCYSNNGSN 0.00788754123538864 9178 142 89 0.626760563380282 0.00969710176509043
TF TF:M10432 Factor: MAZ; motif: GGGMGGGGS 0.00791347169237768 9259 141 89 0.631205673758865 0.00961226914353602
TF TF:M00470_1 Factor: AP-2gamma; motif: GCCYNNGGS; match class: 1 0.00796366613643402 5600 123 55 0.447154471544715 0.00982142857142857
TF TF:M07226 Factor: SP1; motif: NCCCCKCCCCC 0.00796366613643402 8292 143 83 0.58041958041958 0.0100096478533526
TF TF:M00008_1 Factor: Sp1; motif: GGGGCGGGGT; match class: 1 0.00814599698170522 4937 141 56 0.397163120567376 0.0113429208021065
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.00843966660378686 10419 143 98 0.685314685314685 0.00940589307995009
TF TF:M11670_1 Factor: IRF-5; motif: NYGAAACCGAAACY; match class: 1 0.00843966660378686 36 131 4 0.0305343511450382 0.111111111111111
TF TF:M00143 Factor: Pax-5; motif: BCNNNRNGCANBGNTGNRTAGCSGCHNB 0.00843966660378686 11392 142 104 0.732394366197183 0.00912921348314607
TF TF:M09658_1 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS; match class: 1 0.00843966660378686 2033 141 30 0.212765957446809 0.014756517461879
TF TF:M12227_1 Factor: ZIC4; motif: NNCCNCCCRYNGYGN; match class: 1 0.00843966660378686 5898 142 64 0.450704225352113 0.0108511359782977
TF TF:M09907_1 Factor: Erg; motif: NRRSAGGAAGNGG; match class: 1 0.00853203489276722 5070 123 51 0.414634146341463 0.0100591715976331
TF TF:M07045 Factor: IRF-1; motif: NNRAAANNGAAASN 0.00859220994434641 535 138 13 0.0942028985507246 0.0242990654205607
TF TF:M12173_1 Factor: GKLF; motif: NNCCMCRCCCN; match class: 1 0.00859220994434641 4965 141 56 0.397163120567376 0.0112789526686808
TF TF:M08911 Factor: CTCF; motif: NCCRSTAGGGGGCGC 0.00859220994434641 9094 142 88 0.619718309859155 0.00967670991862767
TF TF:M00693_1 Factor: E12; motif: RRCAGGTGNCV; match class: 1 0.00865581988796556 370 58 7 0.120689655172414 0.0189189189189189
TF TF:M01196 Factor: CTF1; motif: TGGCASCNNGCCAA 0.00924806848235746 4864 11 9 0.818181818181818 0.00185032894736842
TF TF:M09984 Factor: MAZ; motif: GGGGGAGGGGGNGRGRRRGNRG 0.0092578897538788 9544 142 91 0.640845070422535 0.00953478625314334
TF TF:M02089_1 Factor: E2F-3; motif: GGCGGGN; match class: 1 0.0101011328159234 9362 141 89 0.631205673758865 0.00950651570177313
TF TF:M11672 Factor: IRF-5; motif: NCGAAACCGAAACY 0.0101011328159234 120 127 6 0.047244094488189 0.05
TF TF:M09629 Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN 0.0101268586591598 336 138 10 0.072463768115942 0.0297619047619048
TF TF:M11664 Factor: IRF-2; motif: NGAAASYGAAAS 0.0101268586591598 1651 143 26 0.181818181818182 0.015748031496063
TF TF:M09970 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN 0.0103740362116468 7728 143 78 0.545454545454545 0.0100931677018634
TF TF:M11685_1 Factor: IRF-8; motif: NCGAAACYGAAACYN; match class: 1 0.0103988426651137 118 131 6 0.0458015267175573 0.0508474576271186
TF TF:M06203_1 Factor: ZXDA; motif: NAGGGTG; match class: 1 0.0104420139803358 2007 126 27 0.214285714285714 0.0134529147982063
TF TF:M06202_1 Factor: ZXDB; motif: NAGGGTG; match class: 1 0.0104420139803358 2007 126 27 0.214285714285714 0.0134529147982063
TF TF:M07039_1 Factor: ETF; motif: CCCCGCCCCYN; match class: 1 0.0105033601159709 13611 144 119 0.826388888888889 0.00874292851370215
TF TF:M09746_1 Factor: HNRPUL1; motif: NCNCAGN; match class: 1 0.0105093957848416 7619 63 39 0.619047619047619 0.00511878199238745
TF TF:M06202 Factor: ZXDB; motif: NAGGGTG 0.0105093957848416 7463 128 69 0.5390625 0.00924561168430926
TF TF:M06203 Factor: ZXDA; motif: NAGGGTG 0.0105093957848416 7463 128 69 0.5390625 0.00924561168430926
TF TF:M03807 Factor: SP2; motif: GNNGGGGGCGGGGSN 0.0105093957848416 8415 143 83 0.58041958041958 0.00986333927510398
TF TF:M12152 Factor: Sp1; motif: NWRGCCACGCCCMCN 0.0105093957848416 7341 141 74 0.524822695035461 0.0100803705217273
TF TF:M00063 Factor: IRF-2; motif: GAAAAGYGAAASY 0.0105865129562549 685 9 4 0.444444444444444 0.00583941605839416
TF TF:M12151 Factor: Sp1; motif: NWRGCCMCGCCCMCN 0.0105865129562549 6821 141 70 0.49645390070922 0.0102624248643894
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.0108267921761915 16244 144 134 0.930555555555556 0.00824919970450628
TF TF:M08775_1 Factor: IRF-2; motif: NAANYGAAASYR; match class: 1 0.011020017877267 2761 140 36 0.257142857142857 0.0130387540746106
TF TF:M10137_1 Factor: ZBP99; motif: NGGNGGGGGAGGGGN; match class: 1 0.0115283125169443 69 80 4 0.05 0.0579710144927536
TF TF:M09972 Factor: BTEB2; motif: WGGGTGKGGCNGGN 0.0115997471376014 9217 131 82 0.625954198473282 0.0088966041011175
TF TF:M07310 Factor: Sp5; motif: ACCSCGCCKCCSS 0.0116493301411146 245 67 6 0.0895522388059701 0.0244897959183673
TF TF:M01724_1 Factor: T3R-alpha; motif: NNTSRGGTCAN; match class: 1 0.0121083794776175 213 11 3 0.272727272727273 0.0140845070422535
TF TF:M08674_1 Factor: AP-4:Max; motif: NCAGCTGNNNNNNNCACGTGN; match class: 1 0.0122660257437382 5667 95 44 0.463157894736842 0.00776424916181401
TF TF:M09862_1 Factor: ZNF614; motif: NCYCWGCCYYNNN; match class: 1 0.0122660257437382 4193 128 45 0.3515625 0.0107321726687336
TF TF:M01835 Factor: GKLF; motif: CCTCCYN 0.0122660257437382 15620 140 127 0.907142857142857 0.00813060179257362
TF TF:M09973_1 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN; match class: 1 0.0122660257437382 6607 141 68 0.482269503546099 0.0102921144240957
TF TF:M07602 Factor: CP2; motif: NNNNCCAGNCNN 0.0122660257437382 11087 122 88 0.721311475409836 0.00793722377559304
TF TF:M01858 Factor: AP-2beta; motif: GCNNNGGSCNGVGGGN 0.0122660257437382 7418 143 75 0.524475524475524 0.0101105419250472
TF TF:M04788_1 Factor: IRF-1; motif: STTTCACTTTCNNT; match class: 1 0.0124219515333114 17 138 3 0.0217391304347826 0.176470588235294
TF TF:M10071 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG 0.0124219515333114 8495 141 82 0.581560283687943 0.00965273690406121
TF TF:M07615_1 Factor: Sp3; motif: GGGGCGGGGSNN; match class: 1 0.012550738875615 2885 141 37 0.26241134751773 0.0128249566724437
TF TF:M08880_1 Factor: ERG; motif: MNNSNGGAAG; match class: 1 0.0128088364547331 205 117 7 0.0598290598290598 0.0341463414634146
TF TF:M07277_1 Factor: BTEB2; motif: RGGGNGKGGN; match class: 1 0.0129048170846918 4149 141 48 0.340425531914894 0.0115690527838033
TF TF:M06273 Factor: ZNF766; motif: KGTGCGGKCCGA 0.0129134056223483 51 116 4 0.0344827586206897 0.0784313725490196
TF TF:M03567 Factor: Sp2; motif: NYSGCCCCGCCCCCY 0.0131571447803342 7710 143 77 0.538461538461538 0.00998702983138781
TF TF:M12158_1 Factor: KLF15; motif: NCCMCGCCCMCN; match class: 1 0.0134371993524559 6004 141 63 0.446808510638298 0.0104930046635576
TF TF:M09733_1 Factor: STAT2; motif: NRGAAANNGAAACTNA; match class: 1 0.0136637223327563 367 137 10 0.072992700729927 0.0272479564032698
TF TF:M07395 Factor: Sp1; motif: NGGGGCGGGGN 0.013838105241443 10640 143 98 0.685314685314685 0.00921052631578947
TF TF:M09958 Factor: IRF-3; motif: RAAARGGAAANNGAAASNGA 0.013838105241443 589 138 13 0.0942028985507246 0.0220713073005093
TF TF:M07407_1 Factor: THAP1; motif: YTGCCCNNA; match class: 1 0.0138472633665239 4197 122 43 0.352459016393443 0.010245413390517
TF TF:M10426 Factor: ctcf; motif: CCRSCAGGGGGCGCN 0.0141008561901511 9305 142 88 0.619718309859155 0.00945728103170339
TF TF:M03831 Factor: MRF4; motif: CASCTGC 0.0142848917773579 8749 146 86 0.589041095890411 0.0098296948222654
TF TF:M02018 Factor: HTF4; motif: CASCTGB 0.0142848917773579 8749 146 86 0.589041095890411 0.0098296948222654
TF TF:M11258_1 Factor: AIBZIP; motif: NGMCACGTGGCN; match class: 1 0.0142848917773579 172 15 3 0.2 0.0174418604651163
TF TF:M09910_1 Factor: ER-beta; motif: RGGTCASCNTGMCCY; match class: 1 0.0143825667943869 4079 122 42 0.344262295081967 0.0102966413336602
TF TF:M12183_1 Factor: KLF14; motif: NRCCACRCCCMCN; match class: 1 0.0143825667943869 2487 141 33 0.234042553191489 0.0132689987937274
TF TF:M07409 Factor: BTEB2; motif: GCCCCRCCCH 0.0143825667943869 5198 143 57 0.398601398601399 0.0109657560600231
TF TF:M00649 Factor: MAZ; motif: GGGGAGGG 0.0147013539362792 9327 142 88 0.619718309859155 0.0094349737321754
TF TF:M04020 Factor: IRF8; motif: NCGAAACCGAAACT 0.0147013539362792 992 131 17 0.129770992366412 0.0171370967741935
TF TF:M09971 Factor: GKLF; motif: WGGGYGKGGC 0.0147013539362792 5546 141 59 0.418439716312057 0.0106382978723404
TF TF:M01721_1 Factor: PUR1; motif: GGGNCAGNN; match class: 1 0.0147013539362792 3414 118 36 0.305084745762712 0.0105448154657293
TF TF:M09746 Factor: HNRPUL1; motif: NCNCAGN 0.0147013539362792 13720 130 108 0.830769230769231 0.00787172011661808
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.0147013539362792 14096 144 121 0.840277777777778 0.00858399545970488
TF TF:M07045_1 Factor: IRF-1; motif: NNRAAANNGAAASN; match class: 1 0.0147013539362792 19 138 3 0.0217391304347826 0.157894736842105
TF TF:M09656 Factor: Smad2; motif: TGTCTGNCACCT 0.0147013539362792 6422 21 15 0.714285714285714 0.00233572095920274
TF TF:M10550_1 Factor: ZNF684; motif: MAAGGGGTGGACTGT; match class: 1 0.0158574897806745 9336 124 78 0.629032258064516 0.0083547557840617
TF TF:M12173 Factor: GKLF; motif: NNCCMCRCCCN 0.0158574897806745 10023 146 95 0.650684931506849 0.00947820013967874
TF TF:M09862 Factor: ZNF614; motif: NCYCWGCCYYNNN 0.015870209495834 9361 142 88 0.619718309859155 0.00940070505287897
TF TF:M04788 Factor: IRF-1; motif: STTTCACTTTCNNT 0.0160018937272329 536 81 9 0.111111111111111 0.0167910447761194
TF TF:M07039 Factor: ETF; motif: CCCCGCCCCYN 0.0160961043274414 16384 144 134 0.930555555555556 0.0081787109375
TF TF:M08229_1 Factor: Elk-1:SREBP-2; motif: RTCACGTGACCGGAAGN; match class: 1 0.0161474186792435 3095 20 10 0.5 0.00323101777059774
TF TF:M00712_1 Factor: myogenin; motif: RGCAGSTG; match class: 1 0.0161474186792435 1875 79 18 0.227848101265823 0.0096
TF TF:M00933 Factor: Sp1; motif: CCCCGCCCCN 0.0161474186792435 9715 143 91 0.636363636363636 0.00936695831188883
TF TF:M00646 Factor: LF-A1; motif: GGGSTCWR 0.0163034073727802 12797 146 114 0.780821917808219 0.00890833789169337
TF TF:M09910 Factor: ER-beta; motif: RGGTCASCNTGMCCY 0.0163693026992094 9520 124 79 0.637096774193548 0.00829831932773109
TF TF:M09602_1 Factor: ctcf; motif: NNNCCASYAGRKGGCRSYNN; match class: 1 0.0166140496156348 2137 113 25 0.221238938053097 0.0116986429574169
TF TF:M00453_1 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN; match class: 1 0.0166140496156348 332 131 9 0.0687022900763359 0.0271084337349398
TF TF:M04018 Factor: IRF7; motif: NCGAAARYGAAANT 0.0177294673244578 619 138 13 0.0942028985507246 0.0210016155088853
TF TF:M11681 Factor: IRF-9; motif: NCGAAACYGAAACYN 0.0177294673244578 97 127 5 0.0393700787401575 0.0515463917525773
TF TF:M00257_1 Factor: RREB-1; motif: CCCCAAACMMCCCC; match class: 1 0.0187388894936812 4475 121 44 0.363636363636364 0.00983240223463687
TF TF:M08805 Factor: EAR2; motif: NCTYTGACCTN 0.0187388894936812 1027 45 9 0.2 0.00876338851022395
TF TF:M09616 Factor: Fra-2; motif: RTGACTCANNN 0.0187632490849238 4760 27 15 0.555555555555556 0.00315126050420168
TF TF:M04750_1 Factor: GR; motif: RGRACATTNTGTYC; match class: 1 0.0187632490849238 1704 9 5 0.555555555555556 0.00293427230046948
TF TF:M04017 Factor: IRF5; motif: NACCGAAACYA 0.0187726244550827 195 138 7 0.0507246376811594 0.0358974358974359
TF TF:M09971_1 Factor: GKLF; motif: WGGGYGKGGC; match class: 1 0.0190249772710312 1352 138 21 0.152173913043478 0.0155325443786982
TF TF:M09602 Factor: ctcf; motif: NNNCCASYAGRKGGCRSYNN 0.0190249772710312 7450 123 65 0.528455284552846 0.0087248322147651
TF TF:M12186 Factor: BTEB4; motif: NCCACGCCCM 0.0190607777191886 9135 146 88 0.602739726027397 0.00963327859879584
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 0.0192261369037977 10494 143 96 0.671328671328671 0.00914808461978273
TF TF:M01783_1 Factor: SP2; motif: GGGCGGGAC; match class: 1 0.0192261369037977 4333 143 49 0.342657342657343 0.0113085621970921
TF TF:M00053 Factor: c-Rel; motif: SGGRNTTTCC 0.0192261369037977 3672 125 39 0.312 0.0106209150326797
TF TF:M09765 Factor: SP1; motif: NRGKGGGCGGGGCN 0.0192844218334568 7469 143 74 0.517482517482518 0.00990761815504084
TF TF:M00646_1 Factor: LF-A1; motif: GGGSTCWR; match class: 1 0.0192844218334568 6320 122 57 0.467213114754098 0.00901898734177215
TF TF:M11673 Factor: IRF-5; motif: NCGAAACCGAAACY 0.0192967585148733 57 127 4 0.031496062992126 0.0701754385964912
TF TF:M07281 Factor: EKLF; motif: NCCMCACCCW 0.0192967585148733 798 26 6 0.230769230769231 0.0075187969924812
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.0206553666533734 10233 143 94 0.657342657342657 0.00918596696960813
TF TF:M00761 Factor: p53; motif: RGRCAWGNCY 0.0208422271198835 2985 18 9 0.5 0.00301507537688442
TF TF:M01224_1 Factor: P50:RELA-P65; motif: GGANTTYCCCWN; match class: 1 0.0208704251393639 236 85 6 0.0705882352941176 0.0254237288135593
TF TF:M10092 Factor: TEF-1; motif: RCATTCCWGNNN 0.0217706702718363 3195 6 5 0.833333333333333 0.00156494522691706
TF TF:M00244 Factor: NGFI-C; motif: WTGCGTGGGYGG 0.0217706702718363 6184 141 63 0.446808510638298 0.0101875808538163
TF TF:M11683_1 Factor: IRF-8; motif: NCGAAACCGAAACYN; match class: 1 0.0217706702718363 814 138 15 0.108695652173913 0.0184275184275184
TF TF:M05327 Factor: WT1; motif: NGCGGGGGGGTSMMCYN 0.0217706702718363 5509 136 56 0.411764705882353 0.0101651842439644
TF TF:M09909 Factor: ER-alpha; motif: AGGTCASMNTGACCY 0.0218528465955944 6836 98 50 0.510204081632653 0.00731421884142774
TF TF:M00056_1 Factor: myogenin; motif: CRSCTGTTBNNTTTGGCACGSNGCCARCH; match class: 1 0.0218528465955944 5754 33 19 0.575757575757576 0.00330205074730622
TF TF:M10529_1 Factor: Sp1; motif: RGGGMGGRGSNGGGG; match class: 1 0.0218528465955944 2816 141 35 0.24822695035461 0.0124289772727273
TF TF:M08568_1 Factor: ER71:E2A; motif: CASSTGNACCGGAWRYN; match class: 1 0.0218528465955944 15133 123 109 0.886178861788618 0.00720280182382872
TF TF:M08885_1 Factor: HAIRYLIKE; motif: NNNNCANGTG; match class: 1 0.0218528465955944 2110 86 20 0.232558139534884 0.00947867298578199
TF TF:M09920 Factor: Fli-1; motif: NNRGGMAGGAAGGRRRGR 0.0218528465955944 9289 117 73 0.623931623931624 0.00785875767036279
TF TF:M01783 Factor: SP2; motif: GGGCGGGAC 0.0218528465955944 9148 141 85 0.602836879432624 0.00929164844774814
TF TF:M01996 Factor: AR; motif: GNNCNNNNTGTTCTN 0.0218528465955944 3085 4 4 1 0.00129659643435981
TF TF:M00915 Factor: AP-2; motif: SNNNCCNCAGGCN 0.0219969853350294 9612 146 91 0.623287671232877 0.00946733250104037
TF TF:M07296 Factor: MAF; motif: GCTGAGTCAN 0.0219969853350294 5670 130 55 0.423076923076923 0.00970017636684303
TF TF:M09658 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS 0.0219969853350294 5262 130 52 0.4 0.00988217407829723
TF TF:M07367 Factor: Slug; motif: SSSNNNKCACCTGN 0.0221659357021952 1680 139 24 0.172661870503597 0.0142857142857143
TF TF:M01858_1 Factor: AP-2beta; motif: GCNNNGGSCNGVGGGN; match class: 1 0.0221659357021952 3141 142 38 0.267605633802817 0.0120980579433301
TF TF:M03868 Factor: CP2; motif: NTGNCTGGNN 0.0221659357021952 4722 127 47 0.37007874015748 0.00995340957221516
TF TF:M04811 Factor: RelA-p65; motif: BCWGGGRANNK 0.0221659357021952 7311 97 52 0.536082474226804 0.00711257009984954
TF TF:M09973 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN 0.0221659357021952 10853 143 98 0.685314685314685 0.00902976135630701
TF TF:M00772_1 Factor: IRF; motif: RRAANTGAAASYGNV; match class: 1 0.0223514099227549 57 138 4 0.0289855072463768 0.0701754385964912
TF TF:M00982_1 Factor: KROX; motif: CCCGCCCCCRCCCC; match class: 1 0.0223514099227549 3518 141 41 0.290780141843972 0.011654349061967
TF TF:M04727 Factor: CTCF; motif: ACCAGGKGGC 0.0223514099227549 6550 142 66 0.464788732394366 0.0100763358778626
TF TF:M09907 Factor: Erg; motif: NRRSAGGAAGNGG 0.0223514099227549 11682 118 87 0.73728813559322 0.00744735490498202
TF TF:M11670 Factor: IRF-5; motif: NYGAAACCGAAACY 0.0223514099227549 871 131 15 0.114503816793893 0.0172215843857635
TF TF:M02281 Factor: SP1; motif: CCCCKCCCCC 0.0223514099227549 6480 141 65 0.460992907801418 0.0100308641975309
TF TF:M00143_1 Factor: Pax-5; motif: BCNNNRNGCANBGNTGNRTAGCSGCHNB; match class: 1 0.0223514099227549 5086 144 55 0.381944444444444 0.0108139992135273
TF TF:M02036_1 Factor: WT1; motif: CGCCCCCNCN; match class: 1 0.0223514099227549 5290 142 56 0.394366197183099 0.010586011342155
TF TF:M10432_1 Factor: MAZ; motif: GGGMGGGGS; match class: 1 0.0223514099227549 4365 144 49 0.340277777777778 0.0112256586483391
TF TF:M09867 Factor: ATF-2; motif: RRTGANGTCAY 0.0223514099227549 4328 36 17 0.472222222222222 0.0039279112754159
TF TF:M11288 Factor: ATF-3; motif: GATGAYGTCATN 0.0223514099227549 5224 36 19 0.527777777777778 0.00363705972434916
TF TF:M05499 Factor: LKLF; motif: NGGGCGG 0.0224023822824865 7900 146 78 0.534246575342466 0.00987341772151899
TF TF:M12042 Factor: TEF-1; motif: NRCATWCCN 0.0224023822824865 5904 6 6 1 0.00101626016260163
TF TF:M12183 Factor: KLF14; motif: NRCCACRCCCMCN 0.0224023822824865 6878 141 68 0.482269503546099 0.00988659494038965
TF TF:M05386 Factor: KLF17; motif: NGGGCGG 0.0224023822824865 7900 146 78 0.534246575342466 0.00987341772151899
TF TF:M01733_1 Factor: MZF-1; motif: TGGGGAR; match class: 1 0.0225764710618311 4931 113 44 0.389380530973451 0.00892313932265261
TF TF:M09972_1 Factor: BTEB2; motif: WGGGTGKGGCNGGN; match class: 1 0.0232510627616747 3919 128 41 0.3203125 0.0104618525133963
TF TF:M11728_1 Factor: NF-1C; motif: NTTGGCNNNNTGCCARN; match class: 1 0.0242643347739308 1129 14 5 0.357142857142857 0.00442869796279894
TF TF:M01072 Factor: HIC1; motif: NSNNNNTGCCCSSNN 0.0243317525811422 4166 140 46 0.328571428571429 0.0110417666826692
TF TF:M00517 Factor: AP-1; motif: NNNTGAGTCAKCN 0.0243317525811422 5023 27 15 0.555555555555556 0.00298626318932909
TF TF:M12140 Factor: Egr-1; motif: NNCRCCCMCGCNN 0.0243317525811422 5360 141 56 0.397163120567376 0.0104477611940299
TF TF:M10115_1 Factor: LRF; motif: NRGGGKCKY; match class: 1 0.0243317525811422 2326 134 29 0.216417910447761 0.0124677558039553
TF TF:M09765_1 Factor: SP1; motif: NRGKGGGCGGGGCN; match class: 1 0.0243317525811422 3318 141 39 0.276595744680851 0.011754068716094
TF TF:M09872 Factor: batf3; motif: NNSTTTCANTNTGASNN 0.0243317525811422 1185 4 3 0.75 0.00253164556962025
TF TF:M01374_1 Factor: six-4; motif: ANNNATGACACCNNNNN; match class: 1 0.0243317525811422 1240 13 5 0.384615384615385 0.00403225806451613
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.0243317525811422 8180 142 78 0.549295774647887 0.00953545232273839
TF TF:M05327_1 Factor: WT1; motif: NGCGGGGGGGTSMMCYN; match class: 1 0.0243317525811422 1757 143 25 0.174825174825175 0.0142287990893569
TF TF:M07129_1 Factor: Sp2; motif: GYCCCGCCYCYNNNN; match class: 1 0.0243995239060443 2422 141 31 0.219858156028369 0.0127993393889348
TF TF:M00450_1 Factor: Zic3; motif: NGGGKGGTC; match class: 1 0.0256742731071933 7927 21 16 0.761904761904762 0.00201841806484168
TF TF:M07226_1 Factor: SP1; motif: NCCCCKCCCCC; match class: 1 0.0257327056196775 3915 141 44 0.312056737588652 0.0112388250319285
TF TF:M03804 Factor: Tal-1; motif: CAGATGG 0.0258388376190094 5362 91 39 0.428571428571429 0.00727340544572921
TF TF:M10528_1 Factor: SNA; motif: NNRGCAGGTGCNNNN; match class: 1 0.026001838026897 781 20 5 0.25 0.00640204865556978
TF TF:M04953 Factor: Sp1; motif: GGNDGGRGGCGGGG 0.0260532170997981 8688 141 81 0.574468085106383 0.0093232044198895
TF TF:M10426_1 Factor: ctcf; motif: CCRSCAGGGGGCGCN; match class: 1 0.0263124034457112 4369 142 48 0.338028169014085 0.0109864957656214
TF TF:M01100 Factor: LRF; motif: GGGGKYNNB 0.0263783311297107 7557 144 74 0.513888888888889 0.00979224560010586
TF TF:M05467 Factor: Sall1; motif: NGGTCCKRGKRA 0.0266059734246082 4211 110 38 0.345454545454545 0.00902398480170981
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.0268408305666201 14473 143 121 0.846153846153846 0.00836039521868306
TF TF:M09884 Factor: CLOCK; motif: CNGNCACGTGNNNM 0.0269640744847906 8420 87 52 0.597701149425287 0.00617577197149644
TF TF:M03922 Factor: SP4; motif: NWRGCCACGCCCMCTYN 0.0278416877805043 6046 141 61 0.432624113475177 0.0100893152497519
TF TF:M11665 Factor: IRF-2; motif: NGAAASYGAAAS 0.0278416877805043 2396 108 25 0.231481481481481 0.0104340567612688
TF TF:M00792_1 Factor: SMAD; motif: AGACNBCNN; match class: 1 0.0278462521464533 429 36 5 0.138888888888889 0.0116550116550117
TF TF:M01721 Factor: PUR1; motif: GGGNCAGNN 0.0278462521464533 9145 122 74 0.60655737704918 0.00809185347184254
TF TF:M00953_1 Factor: AR; motif: NNNGNRRGNACANNGTGTTCTNNNNNN; match class: 1 0.0279009551711005 230 66 5 0.0757575757575758 0.0217391304347826
TF TF:M04636_1 Factor: TFII-I; motif: NAGGAAGTGN; match class: 1 0.0279112598336791 5733 89 40 0.449438202247191 0.00697714983429269
TF TF:M12024 Factor: Tbx3; motif: NAGGTGTSAN 0.027978712770837 4514 19 11 0.578947368421053 0.0024368630926008
TF TF:M00448_1 Factor: Zic1; motif: KGGGTGGTC; match class: 1 0.0284965817264196 4300 70 27 0.385714285714286 0.00627906976744186
TF TF:M00733_1 Factor: SMAD4; motif: GKSRKKCAGMCANCY; match class: 1 0.0286283152495132 2823 129 32 0.248062015503876 0.0113354587318456
TF TF:M10528 Factor: SNA; motif: NNRGCAGGTGCNNNN 0.0287631494667474 4562 27 14 0.518518518518518 0.00306882946076282
TF TF:M00053_1 Factor: c-Rel; motif: SGGRNTTTCC; match class: 1 0.0288496439671649 426 143 10 0.0699300699300699 0.0234741784037559
TF TF:M07249 Factor: ctcf; motif: CCNCNAGRKGGCRSTN 0.0288496439671649 6715 141 66 0.468085106382979 0.00982874162323157
TF TF:M09920_1 Factor: Fli-1; motif: NNRGGMAGGAAGGRRRGR; match class: 1 0.0288496439671649 3358 146 40 0.273972602739726 0.0119118522930316
TF TF:M07353 Factor: E2A; motif: CAGNTGNN 0.0288496439671649 2645 143 33 0.230769230769231 0.012476370510397
TF TF:M01227_1 Factor: MafB; motif: GNTGAC; match class: 1 0.0288826040135669 4745 80 32 0.4 0.00674394099051633
TF TF:M01073 Factor: HIC1; motif: NNNGGKTGCCCSNNNNNN 0.0289436799649914 4088 133 43 0.323308270676692 0.0105185909980431
TF TF:M03806 Factor: ZBTB7C; motif: GKCCCGGGCKG 0.0294091487297804 3031 126 33 0.261904761904762 0.0108874958759485
TF TF:M00973 Factor: E2A; motif: CACCTGNY 0.029546123677022 5425 36 19 0.527777777777778 0.00350230414746544
TF TF:M01303_1 Factor: SP1; motif: GGGGYGGGGNS; match class: 1 0.0296525027889145 3507 123 36 0.292682926829268 0.0102651839178785
TF TF:M04797_1 Factor: Egr-1; motif: CCGCCCMCG; match class: 1 0.0296525027889145 1565 146 23 0.157534246575342 0.0146964856230032
TF TF:M08838 Factor: Sox-9; motif: MACARWGNNNYCNTTNW 0.0296525027889145 4242 23 12 0.521739130434783 0.00282885431400283
TF TF:M01219 Factor: SP1:SP3; motif: CCSCCCCCYCC 0.0303374651193936 6812 142 67 0.471830985915493 0.00983558426306518
TF TF:M11372 Factor: NRL; motif: NAWWNTGCTGACN 0.0308669221850289 628 52 7 0.134615384615385 0.0111464968152866
TF TF:M00192_1 Factor: GR; motif: NNNNNNCNNTNTGTNCTNN; match class: 1 0.0313453128751041 1974 6 4 0.666666666666667 0.00202634245187437
TF TF:M11301_1 Factor: B-ATF; motif: NNAYGACACN; match class: 1 0.0313453128751041 1972 6 4 0.666666666666667 0.00202839756592292
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.0318010954026806 13227 142 112 0.788732394366197 0.00846752854010736
TF TF:M10098 Factor: DP-1; motif: NRNNGGCGGGAANN 0.0318382008783963 7015 141 68 0.482269503546099 0.00969351389878831
TF TF:M07329_1 Factor: Osx; motif: CCNCCCCCNNN; match class: 1 0.0318382008783963 2509 134 30 0.223880597014925 0.0119569549621363
TF TF:M11686_1 Factor: IRF-4; motif: NYGAAASYGAAACYN; match class: 1 0.0319077394374373 452 138 10 0.072463768115942 0.0221238938053097
TF TF:M08825 Factor: NF-1B; motif: KCCAGANWN 0.0319077394374373 5811 70 33 0.471428571428571 0.00567888487351575
TF TF:M05509 Factor: ZAC; motif: KGGGGAAGAA 0.0319192780493848 318 14 3 0.214285714285714 0.00943396226415094
TF TF:M00052 Factor: NF-kappaB; motif: GGGRATTTCC 0.0321035567322355 1874 102 20 0.196078431372549 0.0106723585912487
TF TF:M10529 Factor: Sp1; motif: RGGGMGGRGSNGGGG 0.0322763651508033 6891 141 67 0.475177304964539 0.00972282687563489
TF TF:M06971 Factor: ZNF521; motif: TGGGGKCCCCCA 0.0322763651508033 36 120 3 0.025 0.0833333333333333
TF TF:M04453_1 Factor: AR; motif: RGGWACAYNGTGTWCYN; match class: 1 0.0324654329390529 3794 4 4 1 0.00105429625724829
TF TF:M10637 Factor: Nkx2-3; motif: NSCACTTNNC 0.0325772795856474 1906 19 7 0.368421052631579 0.00367261280167891
TF TF:M07436_1 Factor: WT1; motif: NNGGGNGGGSGN; match class: 1 0.0325772795856474 2405 140 30 0.214285714285714 0.0124740124740125
TF TF:M07261 Factor: LKLF; motif: GGGGTGGKSN 0.0326507510882448 9774 141 88 0.624113475177305 0.00900347861673829
TF TF:M04263 Factor: FOXO4; motif: TTTCCCCACACG 0.0329833081553258 383 43 5 0.116279069767442 0.0130548302872063
TF TF:M09615 Factor: Fra-1; motif: NRTGACTCATN 0.0329833081553258 4111 27 13 0.481481481481481 0.00316224762831428
TF TF:M09610 Factor: ER-beta; motif: NRGGTCANKSTGACCTNN 0.033165274073708 5822 111 48 0.432432432432432 0.0082445894881484
TF TF:M00453 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN 0.0333211781844478 3082 60 19 0.316666666666667 0.00616482803374432
TF TF:M04489_1 Factor: RXRA; motif: GRGGTCAAAGGTCA; match class: 1 0.0333211781844478 507 104 9 0.0865384615384615 0.0177514792899408
TF TF:M03893_1 Factor: WT1; motif: GNGGGGGCGGGG; match class: 1 0.0334227686458196 3980 142 44 0.309859154929577 0.0110552763819095
TF TF:M07340 Factor: TEF-1; motif: ACATTCCWSNN 0.0334227686458196 3879 6 5 0.833333333333333 0.00128899200824955
TF TF:M00187 Factor: USF; motif: GYCACGTGNC 0.0334227686458196 3775 108 34 0.314814814814815 0.00900662251655629
TF TF:M02261 Factor: ESR1; motif: NNNNMAGGTCACCCTGACCY 0.0337082829352221 4773 120 44 0.366666666666667 0.00921852084642782
TF TF:M07242 Factor: AML1; motif: NNACCACAN 0.0338984333332882 1238 9 4 0.444444444444444 0.00323101777059774
TF TF:M01587_1 Factor: FPM315; motif: SRGGGAGGAGGN; match class: 1 0.0339806825440787 546 137 11 0.0802919708029197 0.0201465201465201
TF TF:M01034 Factor: Ebox; motif: NCACSTGNCN 0.0340745549304384 4854 86 34 0.395348837209302 0.00700453234445818
TF TF:M09804_1 Factor: CREB1; motif: NNTGACGTCANN; match class: 1 0.0340745549304384 4634 36 17 0.472222222222222 0.0036685369011653
TF TF:M09804 Factor: CREB1; motif: NNTGACGTCANN 0.0340745549304384 4634 36 17 0.472222222222222 0.0036685369011653
TF TF:M08885 Factor: HAIRYLIKE; motif: NNNNCANGTG 0.0340745549304384 6024 20 13 0.65 0.00215803452855246
TF TF:M09726_1 Factor: GATAD2A; motif: CCTKTG; match class: 1 0.0340745549304384 9052 83 52 0.626506024096386 0.00574458683163942
TF TF:M11252 Factor: Luman; motif: NGCCACGTGKNN 0.034612261529899 314 15 3 0.2 0.00955414012738853
TF TF:M01175 Factor: CKROX; motif: SCCCTCCCC 0.0350599814095588 7292 144 71 0.493055555555556 0.00973669775095996
TF TF:M07126 Factor: Smad2:Smad3:Smad4; motif: NTGTCTGNCACCT 0.0350599814095588 4278 86 31 0.36046511627907 0.0072463768115942
TF TF:M08208 Factor: E2F-3:FOXI1; motif: NGACACCGCGCCCAC 0.0353872102626994 12560 143 108 0.755244755244755 0.00859872611464968
TF TF:M09729 Factor: LUMAN; motif: CYCAGCYYCY 0.0354709975337564 10686 131 88 0.67175572519084 0.00823507392850458
TF TF:M11680 Factor: IRF-9; motif: NYGAAACYGAAACYN 0.0354709975337564 128 131 5 0.0381679389312977 0.0390625
TF TF:M05417 Factor: ZNF641; motif: NAGGGGKGGGGN 0.0354709975337564 127 132 5 0.0378787878787879 0.0393700787401575
TF TF:M11803_1 Factor: NR1B2; motif: RAGGTCATGACCTN; match class: 1 0.0361763710215528 915 12 4 0.333333333333333 0.00437158469945355
TF TF:M00002 Factor: E47; motif: VSNGCAGGTGKNCNN 0.0361902473180405 2423 93 22 0.236559139784946 0.00907965332232769
TF TF:M00037 Factor: NF-E2; motif: TGCTGAGTCAY 0.0361902473180405 6629 27 17 0.62962962962963 0.00256448936491175
TF TF:M10115 Factor: LRF; motif: NRGGGKCKY 0.0362849268241387 7623 123 64 0.520325203252033 0.00839564475928112
TF TF:M10953 Factor: isx; motif: NTCRTTAA 0.0362849268241387 5521 5 5 1 0.000905633037493208
TF TF:M11665_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 0.0368919700643426 246 138 7 0.0507246376811594 0.0284552845528455
TF TF:M09760 Factor: DPF2; motif: NYCACYTCCYCNYYCY 0.0372643628115146 8179 124 68 0.548387096774194 0.00831397481354689
TF TF:M08035 Factor: Rarb; motif: AGGTCANNYARAGGTCA 0.0376279366453857 5962 54 27 0.5 0.00452868165045287
TF TF:M09991_1 Factor: N-Myc; motif: NGCCACGTGSNN; match class: 1 0.0376279366453857 329 15 3 0.2 0.00911854103343465
TF TF:M04849_1 Factor: RelA-p65; motif: AAASTCCC; match class: 1 0.0377522170928152 1170 48 9 0.1875 0.00769230769230769
TF TF:M00189 Factor: AP-2; motif: MKCCCSCNGGCG 0.0378790958106347 10621 142 94 0.661971830985915 0.00885039073533566
TF TF:M00953 Factor: AR; motif: NNNGNRRGNACANNGTGTTCTNNNNNN 0.0378790958106347 2415 3 3 1 0.00124223602484472
TF TF:M10634 Factor: Nkx2-3; motif: NSCACTTNNC 0.0380266113257891 2644 15 7 0.466666666666667 0.00264750378214826
TF TF:M11756_1 Factor: HNF-4alpha; motif: RRGTCCAAAGTCCAN; match class: 1 0.0380266113257891 299 85 6 0.0705882352941176 0.020066889632107
TF TF:M00772 Factor: IRF; motif: RRAANTGAAASYGNV 0.0385095847728661 1029 99 13 0.131313131313131 0.0126336248785228
TF TF:M08933 Factor: JUND:C-FOS; motif: NNATGAGTCATNN 0.0385095847728661 4818 50 22 0.44 0.0045662100456621
TF TF:M04823_1 Factor: E2F-4; motif: NNTTCCCGCCNN; match class: 1 0.0385447627971341 7850 142 74 0.52112676056338 0.00942675159235669
TF TF:M08896 Factor: SIP1; motif: MRDSCAGGTGKCMCM 0.0385447627971341 669 133 12 0.0902255639097744 0.0179372197309417
TF TF:M01652 Factor: p53; motif: RGRCWWGYCYNGRCWWGYYY 0.0385447627971341 8083 27 19 0.703703703703704 0.00235061239638748
TF TF:M08819 Factor: LKLF; motif: CNCCACCCS 0.0385447627971341 5591 140 56 0.4 0.0100160972992309
TF TF:M01196_1 Factor: CTF1; motif: TGGCASCNNGCCAA; match class: 1 0.0385447627971341 1572 4 3 0.75 0.00190839694656489
TF TF:M04217 Factor: MAFK; motif: NAWWNTGCTGAS 0.0386954079895868 940 6 3 0.5 0.00319148936170213
TF TF:M01865_1 Factor: BTEB3; motif: BNRNGGGAGGNGT; match class: 1 0.0386954079895868 4218 140 45 0.321428571428571 0.0106685633001422
TF TF:M01227 Factor: MafB; motif: GNTGAC 0.0386954079895868 11727 146 104 0.712328767123288 0.00886842329666581
TF TF:M09734_1 Factor: ZNF692; motif: SYNGGSCCCASCCNC; match class: 1 0.0386954079895868 6255 116 52 0.448275862068966 0.00831334932054357
TF TF:M07261_1 Factor: LKLF; motif: GGGGTGGKSN; match class: 1 0.0386954079895868 4062 118 38 0.322033898305085 0.00935499753815854
TF TF:M00199_1 Factor: AP-1; motif: NTGASTCAG; match class: 1 0.0386954079895868 4265 27 13 0.481481481481481 0.00304806565064478
TF TF:M00199 Factor: AP-1; motif: NTGASTCAG 0.0386954079895868 4833 27 14 0.518518518518518 0.00289675150010346
TF TF:M02280 Factor: AP1; motif: TGACTCA 0.0386954079895868 4255 27 13 0.481481481481481 0.00305522914218566
TF TF:M02281_1 Factor: SP1; motif: CCCCKCCCCC; match class: 1 0.0386954079895868 2558 141 31 0.219858156028369 0.0121188428459734
TF TF:M09591 Factor: AP-2gamma; motif: NTGSCCTGRGGSNN 0.0386954079895868 8337 108 61 0.564814814814815 0.00731678061652873
TF TF:M07617 Factor: Sp4; motif: SCCCCKCCCCCSN 0.0386954079895868 3595 141 40 0.283687943262411 0.0111265646731572
TF TF:M07300_1 Factor: NF-1C; motif: TTGGCNN; match class: 1 0.0386954079895868 1188 39 8 0.205128205128205 0.00673400673400673
TF TF:M03551 Factor: JunB; motif: TGACTCAN 0.0386954079895868 4253 27 13 0.481481481481481 0.00305666588290618
TF TF:M09649 Factor: Blimp-1; motif: RAAAGTGAAAGTNN 0.0386954079895868 300 17 3 0.176470588235294 0.01
TF TF:M11686 Factor: IRF-4; motif: NYGAAASYGAAACYN 0.0386954079895868 3391 99 29 0.292929292929293 0.0085520495429077
TF TF:M01778 Factor: PLAG1; motif: GRGGCNNHNNNRRGGG 0.038767836587512 2743 132 31 0.234848484848485 0.011301494713817
TF TF:M11718_1 Factor: TGIF2LY; motif: TGACAGSTGTCA; match class: 1 0.0393612342209638 243 21 3 0.142857142857143 0.0123456790123457
TF TF:M09916 Factor: Erm; motif: NRRSAGGAARNGRN 0.0395864789263924 6711 109 52 0.477064220183486 0.00774847265683207
TF TF:M07368 Factor: Smad4; motif: NCAGACAN 0.0395864789263924 3856 112 35 0.3125 0.00907676348547718
TF TF:M11684_1 Factor: IRF-8; motif: NYGAAACYGAAACTN; match class: 1 0.0395864789263924 832 138 14 0.101449275362319 0.0168269230769231
TF TF:M04863 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG 0.039681854995409 13618 129 104 0.806201550387597 0.00763695109414011
TF TF:M02261_1 Factor: ESR1; motif: NNNNMAGGTCACCCTGACCY; match class: 1 0.039964859290732 2420 143 30 0.20979020979021 0.012396694214876
TF TF:M12255 Factor: SNA; motif: NRCAGGTGCN 0.039964859290732 3357 26 11 0.423076923076923 0.00327673518022043
TF TF:M07323_1 Factor: IRF-4; motif: KRAAMNGAAANYN; match class: 1 0.040641569408191 39 131 3 0.0229007633587786 0.0769230769230769
TF TF:M07397 Factor: ZBP89; motif: CCCCKCCCCCNN 0.0406632129290544 7143 141 68 0.482269503546099 0.00951980960380792
TF TF:M05946_1 Factor: PRDM16; motif: KGGTCATRACCM; match class: 1 0.0406632129290544 2282 42 12 0.285714285714286 0.00525854513584575
TF TF:M01009 Factor: HES-1; motif: ANSBCKYGTGSCNNG 0.0409477134889685 3003 50 16 0.32 0.00532800532800533
TF TF:M00638 Factor: HNF4alpha; motif: VTGAACTTTGMMB 0.0410167472665417 2814 8 5 0.625 0.00177683013503909
TF TF:M09762 Factor: NF1B; motif: CYTGGCNYNCWGCCAN 0.0410707584692824 5659 24 14 0.583333333333333 0.00247393532426224
TF TF:M04863_1 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG; match class: 1 0.0410707584692824 8573 142 79 0.556338028169014 0.00921497725417007
TF TF:M11705_1 Factor: MRG2; motif: TGACASSTGTCA; match class: 1 0.0410707584692824 254 104 6 0.0576923076923077 0.0236220472440945
TF TF:M01587 Factor: FPM315; motif: SRGGGAGGAGGN 0.0411166144475904 3246 137 36 0.262773722627737 0.011090573012939
TF TF:M09969 Factor: EKLF; motif: NGGGYGKGGCNNGG 0.0414187535860761 4589 141 48 0.340425531914894 0.0104597951623447
TF TF:M09923 Factor: Fra-2; motif: NNRTGAGTCAYN 0.041895179592746 4336 27 13 0.481481481481481 0.00299815498154982
TF TF:M11687 Factor: IRF-4; motif: NCGAAACCGAAACYN 0.0419780864939738 3595 99 30 0.303030303030303 0.00834492350486787
TF TF:M09984_1 Factor: MAZ; motif: GGGGGAGGGGGNGRGRRRGNRG; match class: 1 0.0419780864939738 5555 142 56 0.394366197183099 0.0100810081008101
TF TF:M07417_1 Factor: Elf-1; motif: NNCAGGAAGNNN; match class: 1 0.0420783416211246 102 108 4 0.037037037037037 0.0392156862745098
TF TF:M01224 Factor: P50:RELA-P65; motif: GGANTTYCCCWN 0.0420984904921379 2329 143 29 0.202797202797203 0.0124516960068699
TF TF:M05332_1 Factor: Sp2; motif: WGGGCGG; match class: 1 0.0420984904921379 3313 80 24 0.3 0.00724418955629339
TF TF:M05361_1 Factor: Sp6; motif: WGGGCGG; match class: 1 0.0420984904921379 3313 80 24 0.3 0.00724418955629339
TF TF:M05444_1 Factor: CPBP; motif: NGGGCGG; match class: 1 0.0420984904921379 3313 80 24 0.3 0.00724418955629339
TF TF:M03876 Factor: Kaiso; motif: GCMGGGRGCRGS 0.0432801728593845 13622 136 109 0.801470588235294 0.00800176185582147
TF TF:M09890_1 Factor: ctcf; motif: YGGCCACCAGRKGGCRSYN; match class: 1 0.0432801728593845 2884 138 33 0.239130434782609 0.0114424410540915
TF TF:M11061 Factor: HES-1; motif: GGCRCGTGNC 0.0434652558459219 6271 122 54 0.442622950819672 0.00861106681549992
TF TF:M08786 Factor: Tbx3; motif: AGGTGTNR 0.0434652558459219 3776 99 31 0.313131313131313 0.00820974576271187
TF TF:M03876_1 Factor: Kaiso; motif: GCMGGGRGCRGS; match class: 1 0.0434652558459219 9106 114 68 0.596491228070175 0.00746760377772897
TF TF:M04467 Factor: HNF4A; motif: RRGGTCAAAGTCCANN 0.0434652558459219 1641 8 4 0.5 0.0024375380865326
TF TF:M01972 Factor: EGR-1; motif: TGCGTGGGCGK 0.0434652558459219 5360 141 54 0.382978723404255 0.0100746268656716
TF TF:M07289 Factor: GKLF; motif: NNNRGGNGNGGSN 0.0436244655818588 14646 146 123 0.842465753424658 0.00839819746005735
TF TF:M00956 Factor: AR; motif: NNNNNNRGNACRNNGTGTTCTNNNNNN 0.0436244655818588 2717 3 3 1 0.00110415899889584
TF TF:M12026 Factor: TBX2; motif: NNNGTGTSNN 0.0436805080305102 7517 106 55 0.518867924528302 0.00731674870294
TF TF:M11988_1 Factor: NFATc3; motif: NTTTCCRYGGAAAN; match class: 1 0.0436805080305102 6648 131 60 0.458015267175573 0.00902527075812274
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.0436805080305102 9162 142 83 0.584507042253521 0.00905915738921633
TF TF:M03582_1 Factor: TWIST; motif: CACCTGG; match class: 1 0.0441019281417854 2579 119 27 0.226890756302521 0.0104691740984878
TF TF:M04808 Factor: HNF4alpha; motif: AAGTYCAG 0.0443830567373984 2945 90 24 0.266666666666667 0.00814940577249576
TF TF:M02088_1 Factor: E2A; motif: NRMCASCTGCNNN; match class: 1 0.0449045001510116 315 117 7 0.0598290598290598 0.0222222222222222
TF TF:M07397_1 Factor: ZBP89; motif: CCCCKCCCCCNN; match class: 1 0.0449343137346927 2951 141 34 0.24113475177305 0.0115215181294476
TF TF:M01724 Factor: T3R-alpha; motif: NNTSRGGTCAN 0.0450139679301288 2615 38 12 0.315789473684211 0.00458891013384321
TF TF:M07204_1 Factor: AR; motif: ARGAACANNNTGTNC; match class: 1 0.045776765492314 963 13 4 0.307692307692308 0.00415368639667705
TF TF:M09897_1 Factor: Egr-1; motif: NNNNGCGKGGGYGGNRN; match class: 1 0.045776765492314 993 146 16 0.10958904109589 0.0161127895266868
TF TF:M12256 Factor: SNA; motif: NRCAGGTGNN 0.0458191478589818 2460 119 26 0.218487394957983 0.0105691056910569
TF TF:M07249_1 Factor: ctcf; motif: CCNCNAGRKGGCRSTN; match class: 1 0.0458191478589818 2074 133 25 0.18796992481203 0.0120540019286403
TF TF:M10530_1 Factor: sp4; motif: NNNGCYCCGCCCCCY; match class: 1 0.0458191478589818 3780 141 41 0.290780141843972 0.0108465608465608
TF TF:M09885 Factor: COE1; motif: NNNTCCCCAGGGANN 0.0458191478589818 589 81 8 0.0987654320987654 0.0135823429541596
TF TF:M00272_1 Factor: p53; motif: NGRCWTGYCY; match class: 1 0.0458597473403532 1167 11 4 0.363636363636364 0.00342759211653813
TF TF:M11685 Factor: IRF-8; motif: NCGAAACYGAAACYN 0.0460702145029248 1617 108 18 0.166666666666667 0.0111317254174397
TF TF:M11718 Factor: TGIF2LY; motif: TGACAGSTGTCA 0.0460702145029248 273 21 3 0.142857142857143 0.010989010989011
TF TF:M05548 Factor: PLAGL2; motif: AAGGACC 0.0461636144906349 4194 76 27 0.355263157894737 0.00643776824034335
TF TF:M11156 Factor: ITF-2; motif: NCACCTGC 0.0461636144906349 1529 26 7 0.269230769230769 0.00457815565729235
TF TF:M04706_1 Factor: RelA; motif: GGGRAWTYC; match class: 1 0.0461636144906349 344 138 8 0.0579710144927536 0.0232558139534884
TF TF:M09762_1 Factor: NF1B; motif: CYTGGCNYNCWGCCAN; match class: 1 0.0461636144906349 1514 14 5 0.357142857142857 0.00330250990752972
TF TF:M09834 Factor: ZNF148; motif: NNNNNNCCNNCCCCTCCCCCACCCN 0.0467396847568575 6953 141 66 0.468085106382979 0.00949230547964907
TF TF:M01305_1 Factor: TEF; motif: YACATTCCWSNG; match class: 1 0.0467396847568575 446 27 4 0.148148148148148 0.00896860986547085
TF TF:M02089 Factor: E2F-3; motif: GGCGGGN 0.0467403360613149 13173 143 111 0.776223776223776 0.0084263265770895
TF TF:M11290 Factor: ATF-3; motif: NATGATGTCATN 0.0473696589103881 6401 38 21 0.552631578947368 0.00328073738478363
TF TF:M09964 Factor: JunD; motif: NRTGAGTCAYN 0.0475719851316614 5047 27 14 0.518518518518518 0.00277392510402219
TF TF:M00001 Factor: MyoD; motif: SRACAGGTGKYG 0.0476364361499227 1365 89 14 0.157303370786517 0.0102564102564103
TF TF:M11248 Factor: Luman; motif: GRTGAYGTCAYN 0.0476364361499227 305 64 5 0.078125 0.0163934426229508
TF TF:M11729_1 Factor: NF-1C; motif: NTTGGCNNNNTGCCARN; match class: 1 0.0487804373367855 917 14 4 0.285714285714286 0.00436205016357688
TF TF:M03565 Factor: slug; motif: KCACCTGN 0.0487804373367855 2984 26 10 0.384615384615385 0.00335120643431635
TF TF:M11155 Factor: ITF-2; motif: NCACCTGN 0.0487804373367855 2984 26 10 0.384615384615385 0.00335120643431635
TF TF:M10090 Factor: Tbx3; motif: NRAGGTGNNAR 0.0488701020499792 5037 12 8 0.666666666666667 0.00158824697240421
TF TF:M01593_1 Factor: Zfx; motif: SNSCAGGCCKCGSCSS; match class: 1 0.0489203340137089 970 51 8 0.156862745098039 0.00824742268041237
TF TF:M02022 Factor: MafK; motif: TGASTCAGCDN 0.0489203340137089 311 39 4 0.102564102564103 0.0128617363344051
TF TF:M01778_1 Factor: PLAG1; motif: GRGGCNNHNNNRRGGG; match class: 1 0.0490870257683958 453 44 5 0.113636363636364 0.011037527593819
TF TF:M11706 Factor: PREP-1; motif: TGACAGCTGTCA 0.0493645099822155 219 90 5 0.0555555555555556 0.0228310502283105
TF TF:M03989 Factor: FLI1; motif: ACCGGAAATCCGGT 0.0493645099822155 10442 146 94 0.643835616438356 0.00900210687607738
TF TF:M07223 Factor: Pax-5; motif: NNRNKCAGYSRAGCRTGAC 0.0493645099822155 5600 119 48 0.403361344537815 0.00857142857142857
TF TF:M09965 Factor: c-Jun; motif: NRTGAGTCAYN 0.0493645099822155 4492 27 13 0.481481481481481 0.00289403383793411
TF TF:M05381 Factor: ZNF826; motif: GKGCWGCAGM 0.0493645099822155 677 43 6 0.13953488372093 0.00886262924667651
TF TF:M11255_1 Factor: AIBZIP; motif: YGCCACGTGGCN; match class: 1 0.0496162670482072 409 15 3 0.2 0.00733496332518337
TF TF:M11397 Factor: Erg; motif: NACCGGATATCCGGTN 0.0499049036438457 12005 146 105 0.719178082191781 0.0087463556851312
WP WP:WP4758 Nephrotic syndrome 0.00852657525634328 45 110 6 0.0545454545454545 0.133333333333333
WP WP:WP4658 Small cell lung cancer 0.00852657525634328 98 110 8 0.0727272727272727 0.0816326530612245
WP WP:WP2572 Primary Focal Segmental Glomerulosclerosis FSGS 0.00852657525634328 74 110 7 0.0636363636363636 0.0945945945945946
WP WP:WP619 Type II interferon signaling (IFNG) 0.0496120892126679 37 84 4 0.0476190476190476 0.108108108108108

pEpiTd02 transcription factor target enrichment of top program genes

TF enrichment of pEpiTd02
Possible regulators of activation of pEpiTd02 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.