pEpiTd25 program activity among Epithelial cells

Activation of pEpiTd25
pEpiTd25 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpiTd25 by different cell subtypes
pEpiTd25 gene program activation among cells of different subtypes (Epithelial cells).

pEpiTd25 top program genes

Top genes of pEpiTd25 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpiTd25 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpiTd25
pEpiTd25 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0030036 actin cytoskeleton organization 1.66548946326021e-05 709 44 13 0.295454545454545 0.0183356840620592
GO:BP GO:0030029 actin filament-based process 3.92396450926171e-05 808 44 13 0.295454545454545 0.0160891089108911
GO:BP GO:0007015 actin filament organization 6.15609932287943e-05 445 44 10 0.227272727272727 0.0224719101123595
GO:BP GO:0097435 supramolecular fiber organization 6.21514149151761e-05 734 44 12 0.272727272727273 0.0163487738419619
GO:BP GO:0007010 cytoskeleton organization 0.00168761203529256 1423 44 14 0.318181818181818 0.00983836964160225
GO:BP GO:0061572 actin filament bundle organization 0.00951189508058398 164 44 5 0.113636363636364 0.0304878048780488
GO:BP GO:0051017 actin filament bundle assembly 0.00951189508058398 161 44 5 0.113636363636364 0.031055900621118
GO:BP GO:0031032 actomyosin structure organization 0.00951189508058398 199 19 4 0.210526315789474 0.0201005025125628
GO:BP GO:0002446 neutrophil mediated immunity 0.00951189508058398 497 76 10 0.131578947368421 0.0201207243460765
GO:BP GO:0010927 cellular component assembly involved in morphogenesis 0.0108027529203248 107 14 3 0.214285714285714 0.0280373831775701
GO:BP GO:0002444 myeloid leukocyte mediated immunity 0.0142300785972222 551 76 10 0.131578947368421 0.0181488203266788
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.0181752622324977 540 82 10 0.121951219512195 0.0185185185185185
GO:BP GO:0110053 regulation of actin filament organization 0.0181752622324977 284 18 4 0.222222222222222 0.0140845070422535
GO:BP GO:0043312 neutrophil degranulation 0.0188128286181732 482 76 9 0.118421052631579 0.0186721991701245
GO:BP GO:0009888 tissue development 0.0188128286181732 2107 16 8 0.5 0.003796867584243
GO:BP GO:0002283 neutrophil activation involved in immune response 0.0188128286181732 485 76 9 0.118421052631579 0.0185567010309278
GO:BP GO:0042119 neutrophil activation 0.020148769435733 498 76 9 0.118421052631579 0.0180722891566265
GO:BP GO:0036230 granulocyte activation 0.0211674066969126 504 76 9 0.118421052631579 0.0178571428571429
GO:BP GO:0038083 peptidyl-tyrosine autophosphorylation 0.0244021512102078 41 60 3 0.05 0.0731707317073171
GO:BP GO:0030855 epithelial cell differentiation 0.0244021512102078 798 4 3 0.75 0.0037593984962406
GO:BP GO:0043299 leukocyte degranulation 0.0256269264675123 535 76 9 0.118421052631579 0.0168224299065421
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.0256269264675123 366 18 4 0.222222222222222 0.0109289617486339
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.0270089404519102 387 18 4 0.222222222222222 0.0103359173126615
GO:BP GO:0002275 myeloid cell activation involved in immune response 0.0270089404519102 547 76 9 0.118421052631579 0.0164533820840951
GO:BP GO:0032989 cellular component morphogenesis 0.0270089404519102 791 16 5 0.3125 0.00632111251580278
GO:BP GO:0045055 regulated exocytosis 0.0300533951931507 785 25 6 0.24 0.00764331210191083
GO:BP GO:0032970 regulation of actin filament-based process 0.0306893738639478 406 18 4 0.222222222222222 0.00985221674876847
GO:BP GO:0031589 cell-substrate adhesion 0.0337909868332403 367 73 7 0.0958904109589041 0.0190735694822888
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.0346564566773549 263 102 7 0.0686274509803922 0.026615969581749
GO:BP GO:0002366 leukocyte activation involved in immune response 0.037574174500613 717 76 10 0.131578947368421 0.0139470013947001
GO:BP GO:0002263 cell activation involved in immune response 0.037574174500613 721 76 10 0.131578947368421 0.013869625520111
GO:BP GO:1902905 positive regulation of supramolecular fiber organization 0.0392792258701189 214 17 3 0.176470588235294 0.014018691588785
GO:BP GO:0034446 substrate adhesion-dependent cell spreading 0.0392792258701189 109 73 4 0.0547945205479452 0.036697247706422
GO:BP GO:0007155 cell adhesion 0.0393159592026761 1492 75 15 0.2 0.0100536193029491
GO:BP GO:0022610 biological adhesion 0.0394705834557044 1499 75 15 0.2 0.0100066711140761
GO:BP GO:0018108 peptidyl-tyrosine phosphorylation 0.0394705834557044 385 75 7 0.0933333333333333 0.0181818181818182
GO:BP GO:0018212 peptidyl-tyrosine modification 0.0396546397196844 388 75 7 0.0933333333333333 0.0180412371134021
GO:BP GO:0006887 exocytosis 0.0416480943349911 904 25 6 0.24 0.00663716814159292
GO:BP GO:1903351 cellular response to dopamine 0.0418470944640978 86 102 4 0.0392156862745098 0.0465116279069767
GO:BP GO:1903350 response to dopamine 0.0418470944640978 87 102 4 0.0392156862745098 0.0459770114942529
GO:BP GO:0042493 response to drug 0.0418470944640978 396 11 3 0.272727272727273 0.00757575757575758
GO:BP GO:0030041 actin filament polymerization 0.0418470944640978 196 44 4 0.0909090909090909 0.0204081632653061
GO:BP GO:0044087 regulation of cellular component biogenesis 0.0418470944640978 990 70 11 0.157142857142857 0.0111111111111111
GO:BP GO:0007212 dopamine receptor signaling pathway 0.0418470944640978 40 102 3 0.0294117647058824 0.075
GO:BP GO:0060429 epithelium development 0.0418470944640978 1325 4 3 0.75 0.00226415094339623
GO:BP GO:0051495 positive regulation of cytoskeleton organization 0.0418470944640978 231 17 3 0.176470588235294 0.012987012987013
GO:BP GO:0016192 vesicle-mediated transport 0.0422135076418785 2180 39 12 0.307692307692308 0.0055045871559633
GO:BP GO:0046470 phosphatidylcholine metabolic process 0.0422135076418785 90 100 4 0.04 0.0444444444444444
GO:BP GO:0051493 regulation of cytoskeleton organization 0.0432187045464651 531 18 4 0.222222222222222 0.00753295668549906
GO:BP GO:0019637 organophosphate metabolic process 0.0440667521127637 1041 100 14 0.14 0.0134486071085495
GO:BP GO:0022607 cellular component assembly 0.0450139084321981 3010 19 9 0.473684210526316 0.00299003322259136
GO:BP GO:0002274 myeloid leukocyte activation 0.0457950877234824 667 36 6 0.166666666666667 0.00899550224887556
GO:BP GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 0.0458361165015825 59 75 3 0.04 0.0508474576271186
GO:BP GO:0008154 actin polymerization or depolymerization 0.0492967800953599 223 44 4 0.0909090909090909 0.0179372197309417
GO:CC GO:0043230 extracellular organelle 2.80306695647166e-06 2263 26 15 0.576923076923077 0.0066283694211224
GO:CC GO:1903561 extracellular vesicle 2.80306695647166e-06 2261 26 15 0.576923076923077 0.00663423264042459
GO:CC GO:0070062 extracellular exosome 2.80306695647166e-06 2176 26 15 0.576923076923077 0.00689338235294118
GO:CC GO:0005615 extracellular space 1.99210164808074e-05 3594 26 17 0.653846153846154 0.00473010573177518
GO:CC GO:0031982 vesicle 7.54065166359347e-05 4055 82 37 0.451219512195122 0.00912453760789149
GO:CC GO:0005886 plasma membrane 0.000115698352140327 5681 68 39 0.573529411764706 0.0068649885583524
GO:CC GO:0062023 collagen-containing extracellular matrix 0.000165919406748707 421 21 6 0.285714285714286 0.0142517814726841
GO:CC GO:0071944 cell periphery 0.000186741190295619 6169 68 40 0.588235294117647 0.00648403306856865
GO:CC GO:0005576 extracellular region 0.00021084967439796 4567 26 17 0.653846153846154 0.00372235603240639
GO:CC GO:0030018 Z disc 0.000257677742341781 126 22 4 0.181818181818182 0.0317460317460317
GO:CC GO:0031674 I band 0.000354293134047864 139 22 4 0.181818181818182 0.0287769784172662
GO:CC GO:0030312 external encapsulating structure 0.0004237530044237 563 21 6 0.285714285714286 0.0106571936056838
GO:CC GO:0031012 extracellular matrix 0.0004237530044237 562 21 6 0.285714285714286 0.0106761565836299
GO:CC GO:0015629 actin cytoskeleton 0.00119532190185112 513 39 7 0.179487179487179 0.01364522417154
GO:CC GO:0030017 sarcomere 0.00135015814836961 208 22 4 0.181818181818182 0.0192307692307692
GO:CC GO:0030016 myofibril 0.00192288890596822 231 22 4 0.181818181818182 0.0173160173160173
GO:CC GO:0043292 contractile fiber 0.00212134398952787 240 22 4 0.181818181818182 0.0166666666666667
GO:CC GO:0005856 cytoskeleton 0.00639436757600341 2332 39 13 0.333333333333333 0.0055746140651801
GO:CC GO:0030141 secretory granule 0.00645519699894877 851 76 11 0.144736842105263 0.0129259694477086
GO:CC GO:0099503 secretory vesicle 0.00789429813675863 1020 76 12 0.157894736842105 0.0117647058823529
GO:CC GO:0101002 ficolin-1-rich granule 0.0105504866817727 184 21 3 0.142857142857143 0.016304347826087
GO:CC GO:0016020 membrane 0.0109061374915537 9838 76 53 0.697368421052632 0.00538727383614556
GO:CC GO:0005782 peroxisomal matrix 0.0128368315267229 53 80 3 0.0375 0.0566037735849057
GO:CC GO:0031907 microbody lumen 0.0128368315267229 53 80 3 0.0375 0.0566037735849057
GO:CC GO:0005737 cytoplasm 0.013452821050763 11911 87 68 0.781609195402299 0.00570900847955671
GO:CC GO:0032154 cleavage furrow 0.0137166853220363 54 82 3 0.0365853658536585 0.0555555555555556
GO:CC GO:0005902 microvillus 0.0143947305390947 91 50 3 0.06 0.032967032967033
GO:CC GO:0031410 cytoplasmic vesicle 0.0212609696240437 2424 82 20 0.24390243902439 0.00825082508250825
GO:CC GO:0097708 intracellular vesicle 0.0212609696240437 2428 82 20 0.24390243902439 0.00823723228995058
GO:CC GO:0070161 anchoring junction 0.022463039487303 836 45 7 0.155555555555556 0.00837320574162679
GO:CC GO:0042581 specific granule 0.0242605587570219 158 76 4 0.0526315789473684 0.0253164556962025
GO:CC GO:0032153 cell division site 0.0242605587570219 72 82 3 0.0365853658536585 0.0416666666666667
GO:CC GO:0005635 nuclear envelope 0.025735784490383 467 27 4 0.148148148148148 0.00856531049250535
GO:CC GO:0030667 secretory granule membrane 0.0257440364788292 303 21 3 0.142857142857143 0.0099009900990099
GO:CC GO:0005911 cell-cell junction 0.0334609367878251 494 45 5 0.111111111111111 0.0101214574898785
GO:CC GO:0031252 cell leading edge 0.0355678394908918 422 18 3 0.166666666666667 0.00710900473933649
GO:CC GO:0034774 secretory granule lumen 0.037993957175705 320 75 5 0.0666666666666667 0.015625
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.0383141086589026 324 75 5 0.0666666666666667 0.0154320987654321
GO:CC GO:0031983 vesicle lumen 0.0386572272561615 326 75 5 0.0666666666666667 0.0153374233128834
GO:CC GO:0012505 endomembrane system 0.0419118280406529 4640 76 28 0.368421052631579 0.00603448275862069
GO:CC GO:0001726 ruffle 0.0419118280406529 179 48 3 0.0625 0.0167597765363128
GO:CC GO:0005938 cell cortex 0.0419911775489707 311 82 5 0.0609756097560976 0.0160771704180064
GO:CC GO:0099512 supramolecular fiber 0.0427026287683904 993 37 6 0.162162162162162 0.00604229607250755
GO:CC GO:0048471 perinuclear region of cytoplasm 0.0427026287683904 735 64 7 0.109375 0.00952380952380952
GO:CC GO:0005925 focal adhesion 0.0432282101381351 420 22 3 0.136363636363636 0.00714285714285714
GO:CC GO:0099081 supramolecular polymer 0.0432282101381351 1001 37 6 0.162162162162162 0.00599400599400599
GO:CC GO:0030055 cell-substrate junction 0.0445597657502683 427 22 3 0.136363636363636 0.00702576112412178
GO:MF GO:0003779 actin binding 0.00146983727010402 448 52 9 0.173076923076923 0.0200892857142857
GO:MF GO:0050839 cell adhesion molecule binding 0.00223199101025042 546 75 11 0.146666666666667 0.0201465201465201
GO:MF GO:0045296 cadherin binding 0.00332749886959295 333 49 7 0.142857142857143 0.021021021021021
GO:MF GO:0051015 actin filament binding 0.00621484287402567 212 39 5 0.128205128205128 0.0235849056603774
GO:MF GO:0044877 protein-containing complex binding 0.00621484287402567 1287 41 11 0.268292682926829 0.00854700854700855
GO:MF GO:0098632 cell-cell adhesion mediator activity 0.0172269571916996 49 53 3 0.0566037735849057 0.0612244897959184
GO:MF GO:0008092 cytoskeletal protein binding 0.0172269571916996 996 52 10 0.192307692307692 0.0100401606425703
GO:MF GO:0016782 transferase activity, transferring sulfur-containing groups 0.0172269571916996 74 86 4 0.0465116279069767 0.0540540540540541
GO:MF GO:0017124 SH3 domain binding 0.022282257616732 129 98 5 0.0510204081632653 0.0387596899224806
GO:MF GO:0098631 cell adhesion mediator activity 0.022282257616732 58 53 3 0.0566037735849057 0.0517241379310345
GO:MF GO:1902936 phosphatidylinositol bisphosphate binding 0.0237420778088241 104 34 3 0.0882352941176471 0.0288461538461538
GO:MF GO:0031267 small GTPase binding 0.0253299647402673 298 74 6 0.0810810810810811 0.0201342281879195
GO:MF GO:0051020 GTPase binding 0.0348109248391415 330 74 6 0.0810810810810811 0.0181818181818182
GO:MF GO:0005509 calcium ion binding 0.0348109248391415 721 47 7 0.148936170212766 0.00970873786407767
GO:MF GO:0008146 sulfotransferase activity 0.0360259931976442 56 86 3 0.0348837209302326 0.0535714285714286
GO:MF GO:0019903 protein phosphatase binding 0.0397543163901916 153 35 3 0.0857142857142857 0.0196078431372549
GO:MF GO:1901981 phosphatidylinositol phosphate binding 0.0411822596131363 172 34 3 0.0882352941176471 0.0174418604651163
GO:MF GO:0016746 transferase activity, transferring acyl groups 0.0411822596131363 261 47 4 0.0851063829787234 0.0153256704980843
GO:MF GO:0005085 guanyl-nucleotide exchange factor activity 0.0428316215643133 217 59 4 0.0677966101694915 0.0184331797235023
GO:MF GO:0019902 phosphatase binding 0.045554124375561 198 35 3 0.0857142857142857 0.0151515151515152
GO:MF GO:0030695 GTPase regulator activity 0.0493763897701911 487 87 7 0.0804597701149425 0.0143737166324435
TF TF:M09726_1 Factor: GATAD2A; motif: CCTKTG; match class: 1 7.18157255194436e-06 9052 78 62 0.794871794871795 0.00684931506849315
TF TF:M08906_1 Factor: TR4; motif: NCCCTGACCYB; match class: 1 5.19400485849057e-05 743 66 15 0.227272727272727 0.0201884253028264
TF TF:M07460 Factor: KLF3; motif: CCMCRCCCNG 6.98518335000503e-05 1437 82 22 0.268292682926829 0.0153096729297147
TF TF:M01652 Factor: p53; motif: RGRCWWGYCYNGRCWWGYYY 6.98518335000503e-05 8083 98 67 0.683673469387755 0.00828900160831375
TF TF:M04595_1 Factor: SALL2; motif: GGGTGGG; match class: 1 6.98518335000503e-05 7373 77 52 0.675324675324675 0.0070527600705276
TF TF:M09671_1 Factor: VDR; motif: RRGGTCANNGRGKTCA; match class: 1 6.98518335000503e-05 2412 74 27 0.364864864864865 0.0111940298507463
TF TF:M09972 Factor: BTEB2; motif: WGGGTGKGGCNGGN 6.98518335000503e-05 9217 77 59 0.766233766233766 0.00640121514592601
TF TF:M07602_1 Factor: CP2; motif: NNNNCCAGNCNN; match class: 1 7.41295454610186e-05 4627 98 47 0.479591836734694 0.0101577696131403
TF TF:M07461_1 Factor: KLF; motif: GGGNGGGG; match class: 1 0.000129231146075473 3397 68 30 0.441176470588235 0.00883132175448926
TF TF:M07461 Factor: KLF; motif: GGGNGGGG 0.000129231146075473 8757 66 50 0.757575757575758 0.00570971793993377
TF TF:M01588 Factor: GKLF; motif: GCCMCRCCCNNN 0.000161964036078736 8944 77 57 0.74025974025974 0.00637298747763864
TF TF:M00444_1 Factor: VDR; motif: GGGKNARNRRGGWSA; match class: 1 0.000165227794722652 4534 60 32 0.533333333333333 0.0070577856197618
TF TF:M11595_1 Factor: GCMa; motif: RTGCGGGTN; match class: 1 0.000188124017692012 5786 104 55 0.528846153846154 0.00950570342205323
TF TF:M12158 Factor: KLF15; motif: NCCMCGCCCMCN 0.000218286333124251 11088 77 64 0.831168831168831 0.00577200577200577
TF TF:M09971 Factor: GKLF; motif: WGGGYGKGGC 0.000288731974564993 5546 79 43 0.544303797468354 0.00775333573746845
TF TF:M09729_1 Factor: LUMAN; motif: CYCAGCYYCY; match class: 1 0.000288731974564993 4645 86 41 0.476744186046512 0.00882669537136706
TF TF:M01835_1 Factor: GKLF; motif: CCTCCYN; match class: 1 0.000288731974564993 10142 98 74 0.755102040816326 0.00729639124433051
TF TF:M09729 Factor: LUMAN; motif: CYCAGCYYCY 0.000288731974564993 10686 62 52 0.838709677419355 0.0048661800486618
TF TF:M07602 Factor: CP2; motif: NNNNCCAGNCNN 0.000314656708434008 11087 98 78 0.795918367346939 0.00703526652836656
TF TF:M02111_1 Factor: NR1B2; motif: NTGACCY; match class: 1 0.00038462509513325 3323 67 28 0.417910447761194 0.00842612097502257
TF TF:M02119 Factor: T3R-beta; motif: RRGNNANNNGAGGWCAN 0.000619689443242571 3585 96 37 0.385416666666667 0.0103207810320781
TF TF:M01721_1 Factor: PUR1; motif: GGGNCAGNN; match class: 1 0.000783763250491758 3414 75 30 0.4 0.00878734622144113
TF TF:M09746_1 Factor: HNRPUL1; motif: NCNCAGN; match class: 1 0.000783763250491758 7619 101 62 0.613861386138614 0.00813755085969287
TF TF:M01588_1 Factor: GKLF; motif: GCCMCRCCCNNN; match class: 1 0.000814877040866332 3962 76 33 0.434210526315789 0.00832912670368501
TF TF:M03876_1 Factor: Kaiso; motif: GCMGGGRGCRGS; match class: 1 0.00149017759538029 9106 77 55 0.714285714285714 0.00603997364375137
TF TF:M10491_1 Factor: ZNF586; motif: CAGGCCYRGAGG; match class: 1 0.00168764292180092 7720 80 51 0.6375 0.00660621761658031
TF TF:M09734_1 Factor: ZNF692; motif: SYNGGSCCCASCCNC; match class: 1 0.00196981451561685 6255 79 44 0.556962025316456 0.0070343725019984
TF TF:M07260 Factor: Ikaros; motif: TGGGAGN 0.00199096458259205 13523 88 78 0.886363636363636 0.00576795089846927
TF TF:M09910_1 Factor: ER-beta; motif: RGGTCASCNTGMCCY; match class: 1 0.00199096458259205 4079 74 32 0.432432432432432 0.00784506006374111
TF TF:M09726 Factor: GATAD2A; motif: CCTKTG 0.00203960965600093 15191 81 77 0.950617283950617 0.00506879073135409
TF TF:M09862_1 Factor: ZNF614; motif: NCYCWGCCYYNNN; match class: 1 0.0021410982291 4193 102 41 0.401960784313726 0.00977820176484617
TF TF:M09972_1 Factor: BTEB2; motif: WGGGTGKGGCNGGN; match class: 1 0.00257210849050295 3919 102 39 0.382352941176471 0.00995151824445011
TF TF:M07261 Factor: LKLF; motif: GGGGTGGKSN 0.00267785839343878 9774 60 46 0.766666666666667 0.00470636382238592
TF TF:M09862 Factor: ZNF614; motif: NCYCWGCCYYNNN 0.00267785839343878 9361 87 61 0.701149425287356 0.00651639782074565
TF TF:M08906 Factor: TR4; motif: NCCCTGACCYB 0.00267785839343878 4530 66 31 0.46969696969697 0.00684326710816777
TF TF:M07261_1 Factor: LKLF; motif: GGGGTGGKSN; match class: 1 0.00302064623879616 4062 60 27 0.45 0.00664697193500739
TF TF:M08964_1 Factor: NR1B1:RXR-ALPHA; motif: RRGGTCANNNNNRGGTCA; match class: 1 0.00319320252306549 1827 60 17 0.283333333333333 0.00930487137383689
TF TF:M10002 Factor: NF-1C; motif: NYTGGCNNYNNGCCARN 0.00319320252306549 6760 87 49 0.563218390804598 0.00724852071005917
TF TF:M00665 Factor: Sp3; motif: ASMCTTGGGSRGGG 0.00319320252306549 7729 98 59 0.602040816326531 0.00763358778625954
TF TF:M09977_1 Factor: Lyl-1; motif: NCAKCTGYTNYCNN; match class: 1 0.0033431841388269 7633 87 53 0.609195402298851 0.00694353465216822
TF TF:M07048 Factor: MafG; motif: CMATGACTCAGCAGA 0.00347945524380445 6972 68 41 0.602941176470588 0.00588066551921974
TF TF:M04756 Factor: sin3A; motif: TGTCCNNGGTGCTG 0.00347945524380445 14257 86 78 0.906976744186046 0.00547099670337378
TF TF:M01652_1 Factor: p53; motif: RGRCWWGYCYNGRCWWGYYY; match class: 1 0.00347945524380445 5253 78 38 0.487179487179487 0.00723396154578336
TF TF:M10074 Factor: Spi-B; motif: NRAAAGAGGAAGTGARA 0.0035079531123519 1611 13 7 0.538461538461538 0.00434512725015518
TF TF:M08826_1 Factor: NF-E4; motif: GTGAGGS; match class: 1 0.0035079531123519 4695 86 38 0.441860465116279 0.0080937167199148
TF TF:M12136 Factor: mbnl2; motif: NYGCYTYGCYTN 0.0035079531123519 5391 41 24 0.585365853658537 0.00445186421814135
TF TF:M07290_1 Factor: GLI; motif: NGACCMCCCAN; match class: 1 0.00366802105470152 1902 102 24 0.235294117647059 0.0126182965299685
TF TF:M06202 Factor: ZXDB; motif: NAGGGTG 0.00366802105470152 7463 36 26 0.722222222222222 0.00348385367814552
TF TF:M06203 Factor: ZXDA; motif: NAGGGTG 0.00366802105470152 7463 36 26 0.722222222222222 0.00348385367814552
TF TF:M10025_1 Factor: p73; motif: NNRCAWGYCCARRCWTGYC; match class: 1 0.00367800586658024 1411 86 18 0.209302325581395 0.0127569099929128
TF TF:M07469 Factor: Tal; motif: GWSNNCABCTGC 0.00367800586658024 4675 69 32 0.463768115942029 0.00684491978609626
TF TF:M01857 Factor: AP-2alpha; motif: NGCCYSNNGSN 0.00380025097000404 9178 88 60 0.681818181818182 0.00653737197646546
TF TF:M10002_1 Factor: NF-1C; motif: NYTGGCNNYNNGCCARN; match class: 1 0.00380025097000404 1693 73 18 0.246575342465753 0.0106320141760189
TF TF:M08819 Factor: LKLF; motif: CNCCACCCS 0.00382900761111579 5591 80 40 0.5 0.00715435521373636
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.00431760903393386 12729 80 68 0.85 0.00534213213920968
TF TF:M09644 Factor: p73; motif: NGRCATGYYTGNRCWTGYYN 0.00438315129760922 3530 97 34 0.350515463917526 0.00963172804532578
TF TF:M07109 Factor: MafK; motif: MNNASTCAGCANWWW 0.0045449495403407 160 9 3 0.333333333333333 0.01875
TF TF:M00807 Factor: Egr; motif: GTGGGSGCRRS 0.00455204486981346 4343 94 38 0.404255319148936 0.00874971218052038
TF TF:M11796_1 Factor: NR1B1; motif: NRGGNCRTGACCTN; match class: 1 0.00455204486981346 4887 76 35 0.460526315789474 0.00716185799058727
TF TF:M04595 Factor: SALL2; motif: GGGTGGG 0.00459479946073831 13013 66 58 0.878787878787879 0.0044570813801583
TF TF:M00257_1 Factor: RREB-1; motif: CCCCAAACMMCCCC; match class: 1 0.00469482879660629 4475 76 33 0.434210526315789 0.00737430167597765
TF TF:M11803 Factor: NR1B2; motif: RAGGTCATGACCTN 0.00488282104633429 3194 86 29 0.337209302325581 0.00907952410770194
TF TF:M09724 Factor: DATF1; motif: SNGGRRGCWGNGGG 0.00488282104633429 8400 71 47 0.661971830985915 0.00559523809523809
TF TF:M09659 Factor: PU.1; motif: NRAAAGAGGAAGTGARA 0.00495221723111627 2523 31 13 0.419354838709677 0.00515259611573524
TF TF:M03923 Factor: SP8; motif: RCCACGCCCMCY 0.0055225582792782 2843 101 30 0.297029702970297 0.0105522335561027
TF TF:M04727_1 Factor: CTCF; motif: ACCAGGKGGC; match class: 1 0.00635258143592711 1579 82 18 0.219512195121951 0.0113996200126662
TF TF:M09969 Factor: EKLF; motif: NGGGYGKGGCNNGG 0.00637302805580955 4589 88 37 0.420454545454545 0.00806275877097407
TF TF:M01733_1 Factor: MZF-1; motif: TGGGGAR; match class: 1 0.00646630047228496 4931 74 34 0.459459459459459 0.00689515311295883
TF TF:M00721 Factor: CACCC-binding; motif: CANCCNNWGGGTGDGG 0.00683404677709154 2925 86 27 0.313953488372093 0.00923076923076923
TF TF:M11297 Factor: jdp2; motif: NRTGASTCAYN 0.00692890428989523 1811 86 20 0.232558139534884 0.0110436223081171
TF TF:M07249_1 Factor: ctcf; motif: CCNCNAGRKGGCRSTN; match class: 1 0.00692890428989523 2074 59 17 0.288135593220339 0.00819672131147541
TF TF:M11796 Factor: NR1B1; motif: NRGGNCRTGACCTN 0.00692890428989523 10670 86 64 0.744186046511628 0.00599812558575445
TF TF:M04727 Factor: CTCF; motif: ACCAGGKGGC 0.00744611768829604 6550 98 51 0.520408163265306 0.00778625954198473
TF TF:M07048_1 Factor: MafG; motif: CMATGACTCAGCAGA; match class: 1 0.00787176304688573 1550 93 19 0.204301075268817 0.012258064516129
TF TF:M02242 Factor: CTCF; motif: YNRCCASYAGRKGGCRSYN 0.00796241946953442 5877 77 39 0.506493506493506 0.00663603879530373
TF TF:M07041_1 Factor: HDAC1; motif: KGCARGGTC; match class: 1 0.00797563822578588 6354 56 32 0.571428571428571 0.00503619767075858
TF TF:M01036 Factor: COUPTF; motif: NNNNNTGACCYTTGNMCNYNGMN 0.00797563822578588 3807 87 32 0.367816091954023 0.00840556868925663
TF TF:M07292 Factor: GLI; motif: NTGGGTGGTN 0.00797563822578588 5763 94 45 0.478723404255319 0.00780843310775638
TF TF:M07296_1 Factor: MAF; motif: GCTGAGTCAN; match class: 1 0.00797563822578588 1108 78 14 0.179487179487179 0.0126353790613718
TF TF:M00008_1 Factor: Sp1; motif: GGGGCGGGGT; match class: 1 0.00807150511548888 4937 78 35 0.448717948717949 0.00708932550131659
TF TF:M11814_1 Factor: T3R-beta; motif: NRGGTCAAAGGTCRN; match class: 1 0.00811538042226037 7275 29 21 0.724137931034483 0.00288659793814433
TF TF:M02105 Factor: NF-E4; motif: CHCCCTCKCCWG 0.00812204884322853 2647 86 25 0.290697674418605 0.00944465432565168
TF TF:M09886 Factor: COUP-TF1; motif: GRGGKSARAGGTCAGNG 0.00825267628354126 5888 55 30 0.545454545454545 0.00509510869565217
TF TF:M10024 Factor: p63; motif: NRCAWGYCCAGRCWTGYNN 0.00825267628354126 2750 88 26 0.295454545454545 0.00945454545454546
TF TF:M10023_1 Factor: p53; motif: NGRCATGYCCAGRCATGYCY; match class: 1 0.0082890352984648 401 73 8 0.10958904109589 0.0199501246882793
TF TF:M05432 Factor: ZSCAN18; motif: TRRCGRCGNMCC 0.00834055301546425 4117 55 24 0.436363636363636 0.00582948749089143
TF TF:M10432 Factor: MAZ; motif: GGGMGGGGS 0.00869352104645768 9259 76 52 0.684210526315789 0.00561615725240307
TF TF:M01973 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC 0.00892082739548563 6167 82 42 0.51219512195122 0.00681044267877412
TF TF:M07407_1 Factor: THAP1; motif: YTGCCCNNA; match class: 1 0.00892082739548563 4197 64 27 0.421875 0.00643316654753395
TF TF:M07260_1 Factor: Ikaros; motif: TGGGAGN; match class: 1 0.00901200759273971 7187 96 53 0.552083333333333 0.00737442604702936
TF TF:M09762_1 Factor: NF1B; motif: CYTGGCNYNCWGCCAN; match class: 1 0.00906499517545086 1514 67 15 0.223880597014925 0.00990752972258917
TF TF:M03876 Factor: Kaiso; motif: GCMGGGRGCRGS 0.00918702436803799 13622 88 76 0.863636363636364 0.00557921010130671
TF TF:M01724_1 Factor: T3R-alpha; motif: NNTSRGGTCAN; match class: 1 0.00918702436803799 213 10 3 0.3 0.0140845070422535
TF TF:M09738 Factor: ZNF511; motif: GGRRGRGGCWGNG 0.00918702436803799 10865 75 57 0.76 0.00524620340543028
TF TF:M10013 Factor: LXR-alpha; motif: NNRRGGTYACTNNAGGNCA 0.00930852482386445 3171 50 19 0.38 0.00599180069378745
TF TF:M09744 Factor: CTCF; motif: NNYGCCCYCTRSTGGN 0.00930852482386445 3838 77 29 0.376623376623377 0.00755601875977071
TF TF:M07108 Factor: MafF; motif: NCTNASTCAGCANWWTNN 0.00930852482386445 246 9 3 0.333333333333333 0.0121951219512195
TF TF:M01259 Factor: CTCF; motif: NNNNNNCCASNAGRKGGCRS 0.00930852482386445 1968 77 19 0.246753246753247 0.00965447154471545
TF TF:M00257 Factor: RREB-1; motif: CCCCAAACMMCCCC 0.00930852482386445 10516 77 57 0.74025974025974 0.00542031190566755
TF TF:M04863_1 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG; match class: 1 0.00930852482386445 8573 102 63 0.617647058823529 0.00734865274699638
TF TF:M08964 Factor: NR1B1:RXR-ALPHA; motif: RRGGTCANNNNNRGGTCA 0.00930852482386445 7003 61 36 0.590163934426229 0.00514065400542625
TF TF:M04831_1 Factor: ZEB1; motif: CAGGTGN; match class: 1 0.00954829025578161 2169 65 18 0.276923076923077 0.00829875518672199
TF TF:M00925_1 Factor: AP-1; motif: NTGACTCAN; match class: 1 0.00959347557770806 224 10 3 0.3 0.0133928571428571
TF TF:M00083_1 Factor: MZF-1; motif: NGNGGGGA; match class: 1 0.00959347557770806 295 35 5 0.142857142857143 0.0169491525423729
TF TF:M07289 Factor: GKLF; motif: NNNRGGNGNGGSN 0.00964922628867016 14646 66 61 0.924242424242424 0.0041649597159634
TF TF:M12354 Factor: ZNF37A; motif: CCYYGGCTCCNTSCCMN 0.00983708012348089 10961 87 65 0.747126436781609 0.00593011586534075
TF TF:M02111 Factor: NR1B2; motif: NTGACCY 0.0098589130166873 9671 23 20 0.869565217391304 0.00206803846551546
TF TF:M03795 Factor: LXR;; motif: NTGACCKNNAGTRACCYNN 0.00998846524202102 6570 88 46 0.522727272727273 0.00700152207001522
TF TF:M07290 Factor: GLI; motif: NGACCMCCCAN 0.00998846524202102 7127 102 55 0.53921568627451 0.00771713203311351
TF TF:M10013_1 Factor: LXR-alpha; motif: NNRRGGTYACTNNAGGNCA; match class: 1 0.00998846524202102 342 91 8 0.0879120879120879 0.0233918128654971
TF TF:M01835 Factor: GKLF; motif: CCTCCYN 0.00998846524202102 15620 83 78 0.939759036144578 0.00499359795134443
TF TF:M00977 Factor: EBF; motif: KTCCCYWGRGA 0.00998846524202102 2283 24 10 0.416666666666667 0.00438020148926851
TF TF:M11830_1 Factor: LRH-1; motif: TGACCTTGRNYCAAGGTCA; match class: 1 0.010176978110291 6100 69 36 0.521739130434783 0.0059016393442623
TF TF:M00646 Factor: LF-A1; motif: GGGSTCWR 0.0104433483417694 12797 67 57 0.850746268656716 0.00445416894584668
TF TF:M10056 Factor: DRRS; motif: GNNGGGWGGG 0.0104539471112288 4799 79 34 0.430379746835443 0.00708480933527818
TF TF:M12151_1 Factor: Sp1; motif: NWRGCCMCGCCCMCN; match class: 1 0.0104754652238226 2548 87 24 0.275862068965517 0.00941915227629513
TF TF:M00378_1 Factor: Pax-4; motif: NNNNNYCACCCB; match class: 1 0.0106917026791763 14711 66 61 0.924242424242424 0.00414655699816464
TF TF:M00965 Factor: LXR,; motif: YGAMCTNNASTRACCYN 0.0108931087147722 3793 94 33 0.351063829787234 0.00870023727919852
TF TF:M12183 Factor: KLF14; motif: NRCCACRCCCMCN 0.0108986302150231 6878 76 42 0.552631578947368 0.00610642628671125
TF TF:M09762 Factor: NF1B; motif: CYTGGCNYNCWGCCAN 0.0111058202825022 5659 61 31 0.508196721311475 0.00547799964658067
TF TF:M00749_1 Factor: SREBP-1; motif: CACSCCA; match class: 1 0.0111789998371793 2768 67 21 0.313432835820896 0.00758670520231214
TF TF:M09643 Factor: p63; motif: NNRCAWGYCTGGRCWTGYN 0.0111789998371793 3928 95 34 0.357894736842105 0.00865580448065173
TF TF:M07231 Factor: TFAP2A; motif: NNNNGCCYSAGGGCA 0.0114045061856852 5315 104 45 0.432692307692308 0.00846660395108184
TF TF:M07474 Factor: Tbx20; motif: SGAGGTGTGAGGSGR 0.0114045061856852 3703 45 19 0.422222222222222 0.00513097488522819
TF TF:M01724 Factor: T3R-alpha; motif: NNTSRGGTCAN 0.0114045061856852 2615 22 10 0.454545454545455 0.00382409177820268
TF TF:M00446 Factor: Spz1; motif: DNNGGRGGGWWNNNN 0.0114045061856852 8655 65 43 0.661538461538462 0.0049682264586944
TF TF:M12153_1 Factor: Sp3; motif: NGCCACGCCCMCN; match class: 1 0.0114045061856852 1938 87 20 0.229885057471264 0.0103199174406605
TF TF:M09724_1 Factor: DATF1; motif: SNGGRRGCWGNGGG; match class: 1 0.0114045061856852 2880 56 19 0.339285714285714 0.00659722222222222
TF TF:M09727 Factor: GEMIN3; motif: NCWGGRARRGRGNGNG 0.0114045061856852 8569 88 55 0.625 0.00641848523748395
TF TF:M04482 Factor: RARA; motif: ARRGGTCANSNGAGGTCA 0.0117600864178677 3852 86 31 0.36046511627907 0.00804776739356179
TF TF:M01875 Factor: ER-beta; motif: GTCANASTGRCCYNR 0.0118409637458111 6452 88 45 0.511363636363636 0.00697458152510849
TF TF:M08487 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG 0.0118409637458111 13942 71 63 0.887323943661972 0.00451872041314015
TF TF:M02021 Factor: LXRbeta:RXRalpha; motif: NGAGGTCACKRNYGG 0.0118409637458111 506 13 4 0.307692307692308 0.00790513833992095
TF TF:M07611 Factor: p54NRB; motif: GRNNNMGGATGRMNNCGGA 0.0121548424779023 6991 80 44 0.55 0.00629380632241453
TF TF:M04109 Factor: RUNX3; motif: NRACCGCAAACCGCAN 0.0127776512515591 9770 71 50 0.704225352112676 0.00511770726714432
TF TF:M09610 Factor: ER-beta; motif: NRGGTCANKSTGACCTNN 0.0128547620710531 5822 73 36 0.493150684931507 0.0061834421161113
TF TF:M10073 Factor: PU.1; motif: NRAAAGAGGAAGTGRNN 0.0128547620710531 2416 20 9 0.45 0.00372516556291391
TF TF:M07382 Factor: Fli-1; motif: MGGAAGT 0.0131877836254392 6837 13 11 0.846153846153846 0.00160889278923504
TF TF:M12286_1 Factor: ZNF647; motif: NYAGGCCYAC; match class: 1 0.0131877836254392 1636 60 14 0.233333333333333 0.00855745721271394
TF TF:M01870 Factor: C-ets-1; motif: AGGAAGN 0.0131877836254392 6837 13 11 0.846153846153846 0.00160889278923504
TF TF:M01973_1 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC; match class: 1 0.0131877836254392 2398 100 25 0.25 0.0104253544620517
TF TF:M08980_1 Factor: VDR:RXR-ALPHA; motif: NRGGTCANNNGGTTCNN; match class: 1 0.0131877836254392 3939 100 35 0.35 0.00888550393500889
TF TF:M02278 Factor: SPI1; motif: AGGAAGT 0.0131877836254392 6837 13 11 0.846153846153846 0.00160889278923504
TF TF:M02242_1 Factor: CTCF; motif: YNRCCASYAGRKGGCRSYN; match class: 1 0.0131877836254392 1253 77 14 0.181818181818182 0.0111731843575419
TF TF:M03579 Factor: PEA3; motif: AGGAAGT 0.0131877836254392 6837 13 11 0.846153846153846 0.00160889278923504
TF TF:M09837 Factor: ZNF449; motif: NNNAGCCCARCC 0.0131877836254392 4264 76 30 0.394736842105263 0.00703564727954972
TF TF:M00646_1 Factor: LF-A1; motif: GGGSTCWR; match class: 1 0.0134385030916788 6320 66 35 0.53030303030303 0.0055379746835443
TF TF:M07289_1 Factor: GKLF; motif: NNNRGGNGNGGSN; match class: 1 0.0134385030916788 10555 64 48 0.75 0.00454760776882994
TF TF:M00155 Factor: ARP-1; motif: TGARCCYTTGAMCCCW 0.0134385030916788 5581 87 40 0.459770114942529 0.00716717434151586
TF TF:M09909 Factor: ER-alpha; motif: AGGTCASMNTGACCY 0.0134385030916788 6836 64 36 0.5625 0.00526623756582797
TF TF:M00037_1 Factor: NF-E2; motif: TGCTGAGTCAY; match class: 1 0.0137459917088543 1710 93 19 0.204301075268817 0.0111111111111111
TF TF:M09643_1 Factor: p63; motif: NNRCAWGYCTGGRCWTGYN; match class: 1 0.0138978286906569 602 88 10 0.113636363636364 0.0166112956810631
TF TF:M03795_1 Factor: LXR;; motif: NTGACCKNNAGTRACCYNN; match class: 1 0.0139546106764455 1468 91 17 0.186813186813187 0.0115803814713896
TF TF:M01857_1 Factor: AP-2alpha; motif: NGCCYSNNGSN; match class: 1 0.0139546106764455 4616 65 28 0.430769230769231 0.00606585788561525
TF TF:M07091 Factor: Fra-1; motif: RRTGASTCAKN 0.0139951634045593 1716 93 19 0.204301075268817 0.0110722610722611
TF TF:M03871 Factor: GLI; motif: MCVNNGACCACCCAV 0.014085648787226 3331 100 31 0.31 0.00930651456019213
TF TF:M08705 Factor: GCMa:HEN1; motif: GCAGCTGNGNNNNNRTGCGGG 0.014085648787226 510 52 7 0.134615384615385 0.0137254901960784
TF TF:M08881_1 Factor: ETSLIKE; motif: NACTTCCTNN; match class: 1 0.0144424362115629 298 10 3 0.3 0.0100671140939597
TF TF:M01721 Factor: PUR1; motif: GGGNCAGNN 0.0144424362115629 9145 88 57 0.647727272727273 0.00623291416074358
TF TF:M00763 Factor: PPAR; motif: TGACCTTTGNCCY 0.0144424362115629 5257 75 34 0.453333333333333 0.00646756705345254
TF TF:M12173_1 Factor: GKLF; motif: NNCCMCRCCCN; match class: 1 0.0144721218635692 4965 76 33 0.434210526315789 0.00664652567975831
TF TF:M03553 Factor: KLF3; motif: CCMCACCCNG 0.0144721218635692 1873 93 20 0.21505376344086 0.0106780565936999
TF TF:M04147 Factor: TFAP2A; motif: NGCCYSAGGCN 0.0144721218635692 5095 104 43 0.413461538461538 0.0084396467124632
TF TF:M01109 Factor: SZF1-1; motif: CCAGGGTAWCAGCNG 0.0144721218635692 4253 77 30 0.38961038961039 0.00705384434516812
TF TF:M00800_1 Factor: AP-2; motif: GSCCSCRGGCNRNRNN; match class: 1 0.0144721218635692 4268 70 28 0.4 0.00656044985941893
TF TF:M12188 Factor: KLF17; motif: NGMCMCRCCCTN 0.0147485023834553 3673 88 30 0.340909090909091 0.0081677103185407
TF TF:M00339_1 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS; match class: 1 0.0147485023834553 1466 6 4 0.666666666666667 0.00272851296043656
TF TF:M10055 Factor: RXR-alpha; motif: NNGNNRNNNARAGGTCANNG 0.0148449395106864 5794 101 46 0.455445544554455 0.00793924749741112
TF TF:M04811 Factor: RelA-p65; motif: BCWGGGRANNK 0.0148449395106864 7311 76 43 0.565789473684211 0.00588154835179866
TF TF:M00528_1 Factor: PPAR; motif: WASNRGGNCAAAGGTCA; match class: 1 0.0148449395106864 501 54 7 0.12962962962963 0.0139720558882236
TF TF:M07252 Factor: Elk-1; motif: CTTCCKG 0.0150404904387773 10328 12 12 1 0.00116189000774593
TF TF:M01207 Factor: c-Ets-2; motif: CTTCCTG 0.0150404904387773 10328 12 12 1 0.00116189000774593
TF TF:M09907_1 Factor: Erg; motif: NRRSAGGAAGNGG; match class: 1 0.0152515347551144 5070 14 10 0.714285714285714 0.0019723865877712
TF TF:M11795 Factor: NR1B1; motif: NRGGTCANNRGGTCAN 0.0152515347551144 7962 87 51 0.586206896551724 0.00640542577241899
TF TF:M12286 Factor: ZNF647; motif: NYAGGCCYAC 0.0154547284894982 6231 75 38 0.506666666666667 0.0060985395602632
TF TF:M07041 Factor: HDAC1; motif: KGCARGGTC 0.0154547284894982 12526 17 17 1 0.00135717707169088
TF TF:M12152_1 Factor: Sp1; motif: NWRGCCACGCCCMCN; match class: 1 0.0154782032414416 2859 87 25 0.28735632183908 0.00874431619447359
TF TF:M00444 Factor: VDR; motif: GGGKNARNRRGGWSA 0.0158588519888114 10308 77 55 0.714285714285714 0.00533566162204113
TF TF:M03868 Factor: CP2; motif: NTGNCTGGNN 0.0159399022197893 4722 96 38 0.395833333333333 0.00804743752647183
TF TF:M07051 Factor: NF-1B; motif: CTGGCASGV 0.0162042683138033 3915 95 33 0.347368421052632 0.00842911877394636
TF TF:M11478 Factor: AP-2beta; motif: NSCCNNNGGSN 0.0162042683138033 9942 71 50 0.704225352112676 0.00502916918125126
TF TF:M09671 Factor: VDR; motif: RRGGTCANNGRGKTCA 0.0164427889855295 8106 82 49 0.597560975609756 0.00604490500863558
TF TF:M04713 Factor: GATA-1; motif: CCTTATCTS 0.0165846996111721 3463 13 8 0.615384615384615 0.00231013572047358
TF TF:M09774 Factor: KLF9; motif: NNCCACACCCACN 0.0167337404030319 801 26 6 0.230769230769231 0.00749063670411985
TF TF:M02272_1 Factor: RXR:RAR; motif: RGKTCANNNRGAGGTCA; match class: 1 0.01680872646869 2244 86 21 0.244186046511628 0.00935828877005348
TF TF:M09828 Factor: CTCF; motif: RSYGCCMYCTRSTGGN 0.01680872646869 3903 77 28 0.363636363636364 0.00717396874199334
TF TF:M12186_1 Factor: BTEB4; motif: NCCACGCCCM; match class: 1 0.01680872646869 3958 76 28 0.368421052631579 0.00707427993936331
TF TF:M10106 Factor: VDR; motif: NRGGTCANNGRGKTCA 0.01680872646869 6955 62 35 0.564516129032258 0.00503235082674335
TF TF:M09963 Factor: JunB; motif: NNTGAGTCANN 0.0174460579406836 905 86 12 0.13953488372093 0.0132596685082873
TF TF:M09746 Factor: HNRPUL1; motif: NCNCAGN 0.0174460579406836 13720 88 75 0.852272727272727 0.005466472303207
TF TF:M09910 Factor: ER-beta; motif: RGGTCASCNTGMCCY 0.0174521007632834 9520 79 53 0.670886075949367 0.0055672268907563
TF TF:M12026 Factor: TBX2; motif: NNNGTGTSNN 0.0174521007632834 7517 75 43 0.573333333333333 0.00572036716775309
TF TF:M04154 Factor: TFAP2C; motif: NGCCTNAGGCN 0.0174521007632834 3271 104 31 0.298076923076923 0.0094772240904922
TF TF:M00973_1 Factor: E2A; motif: CACCTGNY; match class: 1 0.0174521007632834 1041 86 13 0.151162790697674 0.0124879923150817
TF TF:M00002 Factor: E47; motif: VSNGCAGGTGKNCNN 0.0174521007632834 2423 86 22 0.255813953488372 0.00907965332232769
TF TF:M12262 Factor: slug; motif: RRCAGGTGCA 0.0174635280656721 2088 62 16 0.258064516129032 0.00766283524904215
TF TF:M09808_1 Factor: KLF4; motif: MCACACCCTNN; match class: 1 0.0175481518395356 530 26 5 0.192307692307692 0.00943396226415094
TF TF:M08819_1 Factor: LKLF; motif: CNCCACCCS; match class: 1 0.0178797168844448 1532 60 13 0.216666666666667 0.00848563968668407
TF TF:M03819_1 Factor: Elk-1; motif: GGAAGN; match class: 1 0.0178797168844448 7491 25 18 0.72 0.00240288346015218
TF TF:M00927 Factor: AP-4; motif: RNCAGCTGC 0.0179469670014674 6341 97 47 0.484536082474227 0.00741208011354676
TF TF:M09764 Factor: ROX; motif: GNNNCASGTGGS 0.0179469670014674 5809 78 37 0.474358974358974 0.00636942675159236
TF TF:M12258_1 Factor: SNA; motif: NRCAGGTGCA; match class: 1 0.0179469670014674 234 87 6 0.0689655172413793 0.0256410256410256
TF TF:M08339 Factor: HOXB2:Elf-1; motif: SCGGAAGTMRTTA 0.0181018873193314 1690 24 8 0.333333333333333 0.00473372781065089
TF TF:M10106_1 Factor: VDR; motif: NRGGTCANNGRGKTCA; match class: 1 0.0184154897366232 1628 57 13 0.228070175438596 0.00798525798525799
TF TF:M00175 Factor: AP-4; motif: VDCAGCTGNN 0.0184814922481807 2471 69 19 0.27536231884058 0.00768919465803319
TF TF:M08571 Factor: Erm:E2A; motif: CASGTGNNNCGGAAGNN 0.0185624991922852 11237 65 50 0.769230769230769 0.00444958618848447
TF TF:M00448_1 Factor: Zic1; motif: KGGGTGGTC; match class: 1 0.0185624991922852 4300 36 17 0.472222222222222 0.00395348837209302
TF TF:M09971_1 Factor: GKLF; motif: WGGGYGKGGC; match class: 1 0.0185624991922852 1352 68 13 0.191176470588235 0.00961538461538462
TF TF:M00075 Factor: GATA-1; motif: SNNGATNNNN 0.0192552165795885 7018 80 43 0.5375 0.006127101738387
TF TF:M08881 Factor: ETSLIKE; motif: NACTTCCTNN 0.0193296775402457 3140 21 10 0.476190476190476 0.00318471337579618
TF TF:M09977 Factor: Lyl-1; motif: NCAKCTGYTNYCNN 0.0197310009591284 13787 60 53 0.883333333333333 0.00384420105896859
TF TF:M03921 Factor: SP3; motif: NCCACGCCCMC 0.0200414282717726 3856 68 25 0.367647058823529 0.00648340248962656
TF TF:M07292_1 Factor: GLI; motif: NTGGGTGGTN; match class: 1 0.0200414282717726 1193 97 15 0.154639175257732 0.0125733445096396
TF TF:M12157 Factor: KLF15; motif: RCCACGCCCCCC 0.0200829016329349 3619 76 26 0.342105263157895 0.00718430505664548
TF TF:M07371 Factor: ZEB; motif: NNNCAGGTGNSN 0.0200829016329349 644 60 8 0.133333333333333 0.0124223602484472
TF TF:M04689 Factor: CTCF; motif: NNNNANASYGCCMYCTAGTGG 0.0200829016329349 5648 86 39 0.453488372093023 0.00690509915014164
TF TF:M00340_1 Factor: c-Ets; motif: KRCAGGAARTRNKT; match class: 1 0.0208108659274159 906 10 4 0.4 0.00441501103752759
TF TF:M01200 Factor: CTCF; motif: NNNGCCASCAGRKGGCRSNN 0.0210115079242204 3956 100 34 0.34 0.00859453993933266
TF TF:M11297_1 Factor: jdp2; motif: NRTGASTCAYN; match class: 1 0.0210749831648646 1667 86 17 0.197674418604651 0.0101979604079184
TF TF:M00644_1 Factor: LBP-1; motif: CAGCTGS; match class: 1 0.0210749831648646 4046 69 26 0.376811594202899 0.00642609985170539
TF TF:M01100_1 Factor: LRF; motif: GGGGKYNNB; match class: 1 0.0214017886325194 2762 73 21 0.287671232876712 0.00760318609703114
TF TF:M12259 Factor: slug; motif: NRCAGGTGCR 0.021425021766789 1780 74 16 0.216216216216216 0.00898876404494382
TF TF:M01778 Factor: PLAG1; motif: GRGGCNNHNNNRRGGG 0.0218348426743959 2743 104 27 0.259615384615385 0.00984323733138899
TF TF:M08980 Factor: VDR:RXR-ALPHA; motif: NRGGTCANNNGGTTCNN 0.0218743001384567 10442 29 24 0.827586206896552 0.00229841026623252
TF TF:M09617 Factor: c-Fos; motif: RTGAGTCAYNN 0.0218743001384567 2663 86 23 0.267441860465116 0.00863687570409313
TF TF:M11842 Factor: ER-alpha; motif: NAGGTCAYSGYGACCTN 0.0218743001384567 4035 73 27 0.36986301369863 0.00669144981412639
TF TF:M09893 Factor: E2F-3; motif: NNGGCGGGAAA 0.0218743001384567 6065 71 35 0.492957746478873 0.00577081615828524
TF TF:M01728 Factor: EAR2; motif: YGNNCTTTGNCCTK 0.022288000007189 6372 73 37 0.506849315068493 0.00580665411173886
TF TF:M01596 Factor: Gli3; motif: STGGGTGGYCY 0.022288000007189 2196 97 22 0.22680412371134 0.0100182149362477
TF TF:M12354_1 Factor: ZNF37A; motif: CCYYGGCTCCNTSCCMN; match class: 1 0.0223790893085463 5624 76 35 0.460526315789474 0.00622332859174964
TF TF:M02004 Factor: GATA-1; motif: NNNNNWGATARNNNN 0.0224524858109119 2312 5 4 0.8 0.00173010380622837
TF TF:M08870 Factor: DEC1; motif: NCNCACRTGNSC 0.0227549430058474 7944 87 50 0.574712643678161 0.00629405840886203
TF TF:M08965 Factor: NR1B1:RXR-GAMMA; motif: RRGGTCANNNNNRGGTCA 0.023624664611911 3981 60 23 0.383333333333333 0.00577744285355438
TF TF:M07409_1 Factor: BTEB2; motif: GCCCCRCCCH; match class: 1 0.023624664611911 1829 87 18 0.206896551724138 0.00984144341170038
TF TF:M00698_1 Factor: HEB; motif: RCCWGCTG; match class: 1 0.023624664611911 372 60 6 0.1 0.0161290322580645
TF TF:M02076 Factor: Spi-B; motif: NGNGGAAGYN 0.023624664611911 303 13 3 0.230769230769231 0.0099009900990099
TF TF:M11295 Factor: jdp2; motif: NATGASTCATN 0.023882345937948 44 86 3 0.0348837209302326 0.0681818181818182
TF TF:M12119 Factor: FPM315; motif: NGTGCTCCCN 0.0240688253007691 1239 4 3 0.75 0.00242130750605327
TF TF:M07600_1 Factor: C-Fos; motif: NNTGACTCAN; match class: 1 0.0241610449317263 279 80 6 0.075 0.021505376344086
TF TF:M09769 Factor: CTCFL; motif: CNSCAGGGGGCRSN 0.0246447019194833 812 75 10 0.133333333333333 0.0123152709359606
TF TF:M09973_1 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN; match class: 1 0.0250742546134666 6607 76 39 0.513157894736842 0.00590283033146663
TF TF:M10435_1 Factor: Sp2; motif: GGGGCGGGG; match class: 1 0.0251128525954994 3495 76 25 0.328947368421053 0.00715307582260372
TF TF:M07063_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.0251128525954994 3495 76 25 0.328947368421053 0.00715307582260372
TF TF:M07436 Factor: WT1; motif: NNGGGNGGGSGN 0.0251128525954994 6182 73 36 0.493150684931507 0.0058233581365254
TF TF:M03920_1 Factor: SP1; motif: RCCMCRCCCMC; match class: 1 0.0251429887016328 3020 87 25 0.28735632183908 0.00827814569536424
TF TF:M10530_1 Factor: sp4; motif: NNNGCYCCGCCCCCY; match class: 1 0.0251429887016328 3780 94 31 0.329787234042553 0.0082010582010582
TF TF:M00448 Factor: Zic1; motif: KGGGTGGTC 0.0251945663664952 10948 37 30 0.810810810810811 0.00274022652539277
TF TF:M00470_1 Factor: AP-2gamma; motif: GCCYNNGGS; match class: 1 0.025346238995666 5600 77 35 0.454545454545455 0.00625
TF TF:M01303_1 Factor: SP1; motif: GGGGYGGGGNS; match class: 1 0.025346238995666 3507 56 20 0.357142857142857 0.00570287995437696
TF TF:M00176 Factor: AP-4; motif: CWCAGCTGGN 0.0259097322336797 2528 45 14 0.311111111111111 0.0055379746835443
TF TF:M03582_1 Factor: TWIST; motif: CACCTGG; match class: 1 0.0260260490133935 2579 64 18 0.28125 0.00697944939899186
TF TF:M05629 Factor: ZNF44; motif: KGATSGRGCCSC 0.0261527134827723 276 15 3 0.2 0.0108695652173913
TF TF:M07455 Factor: Gli2; motif: NTGGGTGGTCNN 0.0261801992110071 2857 97 26 0.268041237113402 0.00910045502275114
TF TF:M00518_1 Factor: PPARalpha:RXRalpha; motif: NNRGGTCATWGGGGTSANG; match class: 1 0.0264769794304224 3013 102 28 0.274509803921569 0.00929306339196814
TF TF:M00979_1 Factor: Pax-6; motif: CTGACCTGGAACTM; match class: 1 0.0265618967990547 3068 68 21 0.308823529411765 0.00684485006518905
TF TF:M09808 Factor: KLF4; motif: MCACACCCTNN 0.026789492412388 3799 102 33 0.323529411764706 0.00868649644643327
TF TF:M09640 Factor: NF-1C; motif: NYYTGGCWNNNNKCCMN 0.0267981201870411 2807 104 27 0.259615384615385 0.00961881011756324
TF TF:M03582 Factor: TWIST; motif: CACCTGG 0.0274091017959723 8446 64 40 0.625 0.00473596968979399
TF TF:M08936 Factor: C-JUN:FOSB; motif: NATGACTCAY 0.0276670032514253 3271 86 26 0.302325581395349 0.00794863955976765
TF TF:M00034_1 Factor: p53; motif: GGACATGCCCGGGCATGTCY; match class: 1 0.0276670032514253 2646 63 18 0.285714285714286 0.00680272108843537
TF TF:M10477_1 Factor: ZNF436; motif: TCCTCCAGGAAGCCY; match class: 1 0.0281109515293317 8681 95 57 0.6 0.00656606381753254
TF TF:M01034 Factor: Ebox; motif: NCACSTGNCN 0.0281109515293317 4854 85 34 0.4 0.00700453234445818
TF TF:M07291 Factor: GLI2; motif: TGGGTGGTCNS 0.0283460534451386 3040 97 27 0.278350515463918 0.00888157894736842
TF TF:M10023 Factor: p53; motif: NGRCATGYCCAGRCATGYCY 0.0285364282247476 2746 86 23 0.267441860465116 0.00837581937363438
TF TF:M07039_1 Factor: ETF; motif: CCCCGCCCCYN; match class: 1 0.0286418985746065 13611 78 66 0.846153846153846 0.00484901917566674
TF TF:M08897_1 Factor: SMAD; motif: TGTCTGNNN; match class: 1 0.0286884838590948 661 15 4 0.266666666666667 0.00605143721633888
TF TF:M08019 Factor: RARA; motif: AGGTCANNYAAAGGTCA 0.0286884838590948 5530 62 29 0.467741935483871 0.00524412296564195
TF TF:M08214 Factor: Elk-1:ETV7; motif: ANSCGGACGGATDTCCGGNT 0.0289738653601904 7951 86 49 0.569767441860465 0.00616274682429883
TF TF:M00634 Factor: GCM; motif: CNNRCCCGCATD 0.029041987023824 2152 102 22 0.215686274509804 0.0102230483271375
TF TF:M03818_1 Factor: egr-3; motif: GTGGGY; match class: 1 0.0293864619482146 6724 71 37 0.52112676056338 0.00550267697798929
TF TF:M08441_1 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG; match class: 1 0.0294484004264512 12761 21 20 0.952380952380952 0.00156727529190502
TF TF:M09631 Factor: JunB; motif: NNNTGAGTCAY 0.029639279212536 1915 86 18 0.209302325581395 0.00939947780678851
TF TF:M08765 Factor: GATA-1; motif: NGATAAN 0.0299775042083723 3421 9 6 0.666666666666667 0.00175387313650979
TF TF:M08925 Factor: JUNB:C-FOS; motif: NATGAGTCATNN 0.0299775042083723 3490 86 27 0.313953488372093 0.00773638968481375
TF TF:M10038 Factor: PPARgamma; motif: NWSTRGGKSARAGGKCA 0.0299775042083723 6667 53 29 0.547169811320755 0.00434978251087446
TF TF:M04811_1 Factor: RelA-p65; motif: BCWGGGRANNK; match class: 1 0.0299775042083723 1834 62 14 0.225806451612903 0.00763358778625954
TF TF:M12162 Factor: KLF3; motif: GRCCACGCCCN 0.0299775042083723 1163 85 13 0.152941176470588 0.0111779879621668
TF TF:M10025 Factor: p73; motif: NNRCAWGYCCARRCWTGYC 0.0299775042083723 6293 88 42 0.477272727272727 0.00667408231368187
TF TF:M08227 Factor: Elk-1:PDEF; motif: NCMGGAMGGANATCCGGN 0.0299775042083723 8419 86 51 0.593023255813954 0.00605772657085164
TF TF:M00789 Factor: GATA; motif: WGATARN 0.0299775042083723 3421 9 6 0.666666666666667 0.00175387313650979
TF TF:M09734 Factor: ZNF692; motif: SYNGGSCCCASCCNC 0.0299775042083723 11678 82 62 0.75609756097561 0.00530912827538962
TF TF:M03216 Factor: GATA-6; motif: AGATAAN 0.0299775042083723 3421 9 6 0.666666666666667 0.00175387313650979
TF TF:M07214 Factor: GATA3; motif: AGATAAGA 0.0299775042083723 3417 9 6 0.666666666666667 0.00175592625109745
TF TF:M09924 Factor: c-Fos; motif: NTGAGTCAN 0.0307743780101273 2431 86 21 0.244186046511628 0.00863842040312628
TF TF:M00460 Factor: STAT5A; motif: TTCCNRGAANNNNNNTTCCNNGRR 0.0307743780101273 7764 7 7 1 0.000901597114889232
TF TF:M02092 Factor: Egr-2; motif: CCCMCNCN 0.0312299952172016 4942 66 28 0.424242424242424 0.0056657223796034
TF TF:M10173 Factor: ZNF323; motif: RGCAGCAGGGCARTNAKR 0.0318980902420723 1210 73 12 0.164383561643836 0.00991735537190083
TF TF:M03847 Factor: Sox-15; motif: ACAAWGGG 0.0321089600856783 1583 96 17 0.177083333333333 0.0107391029690461
TF TF:M03870_1 Factor: Fra-2; motif: TGASTCANCN; match class: 1 0.0321789800050594 902 97 12 0.123711340206186 0.0133037694013304
TF TF:M03869 Factor: Fra-1; motif: TGACTCAN 0.0321789800050594 3514 86 27 0.313953488372093 0.0076835515082527
TF TF:M09738_1 Factor: ZNF511; motif: GGRRGRGGCWGNG; match class: 1 0.0323611109369883 4738 88 34 0.386363636363636 0.0071760236386661
TF TF:M07062 Factor: RREB-1; motif: GRSDSGGGKTGGGKGG 0.0323611109369883 1466 86 15 0.174418604651163 0.0102319236016371
TF TF:M01073_1 Factor: HIC1; motif: NNNGGKTGCCCSNNNNNN; match class: 1 0.0323611109369883 762 45 7 0.155555555555556 0.00918635170603675
TF TF:M03831_1 Factor: MRF4; motif: CASCTGC; match class: 1 0.0324337258460256 2796 86 23 0.267441860465116 0.00822603719599428
TF TF:M02018_1 Factor: HTF4; motif: CASCTGB; match class: 1 0.0324337258460256 2796 86 23 0.267441860465116 0.00822603719599428
TF TF:M09615_1 Factor: Fra-1; motif: NRTGACTCATN; match class: 1 0.0324689421887297 559 45 6 0.133333333333333 0.0107334525939177
TF TF:M07092 Factor: Fra-2; motif: NRRTGASTCAB 0.0324689421887297 3156 86 25 0.290697674418605 0.00792141951837769
TF TF:M08955_1 Factor: FXR:RXR-ALPHA; motif: NRGGTCANRGGKN; match class: 1 0.0324689421887297 3333 29 12 0.413793103448276 0.0036003600360036
TF TF:M08938 Factor: C-JUN:FRA-1; motif: NNATGACTCATNN 0.0325431923214551 3714 86 28 0.325581395348837 0.00753904146472806
TF TF:M03815 Factor: c-Fos; motif: TGACTCAN 0.0325431923214551 2455 86 21 0.244186046511628 0.00855397148676171
TF TF:M08252 Factor: ER71:EVX1; motif: NNCGGWAATNNNNATTWN 0.0325431923214551 236 20 3 0.15 0.0127118644067797
TF TF:M07455_1 Factor: Gli2; motif: NTGGGTGGTCNN; match class: 1 0.0325431923214551 255 97 6 0.0618556701030928 0.0235294117647059
TF TF:M12163 Factor: KLF3; motif: GRCCRCGCCCN 0.0325431923214551 733 74 9 0.121621621621622 0.0122783083219645
TF TF:M09922_1 Factor: Fra-1; motif: NNNTGAGTCAYN; match class: 1 0.0325431923214551 677 80 9 0.1125 0.0132939438700148
TF TF:M01273_1 Factor: SP4; motif: SCCCCGCCCCS; match class: 1 0.0325431923214551 1016 87 12 0.137931034482759 0.0118110236220472
TF TF:M06082 Factor: ZNF716; motif: NCAGGCAGCGGA 0.0325431923214551 151 66 4 0.0606060606060606 0.0264900662251656
TF TF:M01733 Factor: MZF-1; motif: TGGGGAR 0.0330252395620087 11391 78 58 0.743589743589744 0.00509173909226582
TF TF:M01783 Factor: SP2; motif: GGGCGGGAC 0.0330252395620087 9148 77 49 0.636363636363636 0.00535636204634893
TF TF:M09748 Factor: RAD21; motif: NCCASYAGRKGGCRSNN 0.0330252395620087 2016 77 17 0.220779220779221 0.00843253968253968
TF TF:M09909_1 Factor: ER-alpha; motif: AGGTCASMNTGACCY; match class: 1 0.0330252395620087 2409 82 20 0.24390243902439 0.008302200083022
TF TF:M00469 Factor: AP-2alpha; motif: GCCNNNRGS 0.0332638888958037 5147 82 34 0.414634146341463 0.00660578978045463
TF TF:M11828 Factor: LRH-1; motif: TCAAGGTCRYGACCTTGR 0.0336443334185709 10627 28 23 0.821428571428571 0.00216429848499106
TF TF:M00470 Factor: AP-2gamma; motif: GCCYNNGGS 0.0336443334185709 9422 77 50 0.649350649350649 0.00530672893228614
TF TF:M00037 Factor: NF-E2; motif: TGCTGAGTCAY 0.0336443334185709 6629 80 40 0.5 0.00603409262332177
TF TF:M07266 Factor: p300; motif: CTGNCTYMAN 0.0336443334185709 8162 87 50 0.574712643678161 0.00612594952217594
TF TF:M04482_1 Factor: RARA; motif: ARRGGTCANSNGAGGTCA; match class: 1 0.0336553533452846 507 10 3 0.3 0.00591715976331361
TF TF:M03920 Factor: SP1; motif: RCCMCRCCCMC 0.0343774106632032 7283 76 41 0.539473684210526 0.0056295482630784
TF TF:M12160_1 Factor: KLF15; motif: RCCMCRCCCMCN; match class: 1 0.0344007366309118 8031 76 44 0.578947368421053 0.00547876976715228
TF TF:M11478_1 Factor: AP-2beta; motif: NSCCNNNGGSN; match class: 1 0.0345970590013871 8037 7 7 1 0.00087097175563021
TF TF:M08471 Factor: Fli-1:HOXB13; motif: NNCGGAARYNRTWAA 0.0345970590013871 5224 7 6 0.857142857142857 0.00114854517611026
TF TF:M12151 Factor: Sp1; motif: NWRGCCMCGCCCMCN 0.0345970590013871 6821 55 30 0.545454545454545 0.00439818208473831
TF TF:M00072 Factor: CP2; motif: GCHCDAMCCAG 0.0345970590013871 8876 17 14 0.823529411764706 0.00157728706624606
TF TF:M11803_1 Factor: NR1B2; motif: RAGGTCATGACCTN; match class: 1 0.0345970590013871 915 85 11 0.129411764705882 0.0120218579234973
TF TF:M03804_1 Factor: Tal-1; motif: CAGATGG; match class: 1 0.0346511974723692 912 73 10 0.136986301369863 0.0109649122807018
TF TF:M03821_1 Factor: ER-beta; motif: ANNSTGACCYRGNN; match class: 1 0.0346511974723692 1368 14 5 0.357142857142857 0.00365497076023392
TF TF:M03899 Factor: EGR4; motif: NNMCGCCCACGCANNN 0.0350010903675866 2037 77 17 0.220779220779221 0.00834560628375061
TF TF:M01073 Factor: HIC1; motif: NNNGGKTGCCCSNNNNNN 0.035214124384675 4088 65 24 0.369230769230769 0.00587084148727984
TF TF:M01743_1 Factor: ING4; motif: CCACCA; match class: 1 0.0355075569626474 10566 10 10 1 0.000946431951542684
TF TF:M01871 Factor: COE1; motif: NCYCWRGGGANYNN 0.0356167247121654 1650 12 5 0.416666666666667 0.00303030303030303
TF TF:M08952 Factor: NF-KAPPAB1; motif: NGGKRNTTYCCCN 0.0361119506618239 7763 87 48 0.551724137931034 0.00618317660698184
TF TF:M03547_1 Factor: ER-alpha; motif: TGACCYN; match class: 1 0.0361119506618239 732 62 8 0.129032258064516 0.0109289617486339
TF TF:M07121 Factor: Blimp-1; motif: NRAAAGTGAAAGTNN 0.0364054338791149 401 13 3 0.230769230769231 0.00748129675810474
TF TF:M10045 Factor: RAR-gamma; motif: RGGTCANNNTGNCCNNNN 0.0364054338791149 7399 29 19 0.655172413793103 0.00256791458305176
TF TF:M11800 Factor: NR1B2; motif: RAGGTCRTGACCTY 0.0364054338791149 3716 87 28 0.32183908045977 0.00753498385360603
TF TF:M00531 Factor: nerf; motif: YRNCAGGAAGYRGSTBDS 0.0364054338791149 7615 12 10 0.833333333333333 0.00131319763624425
TF TF:M10491 Factor: ZNF586; motif: CAGGCCYRGAGG 0.0364054338791149 13875 75 64 0.853333333333333 0.00461261261261261
TF TF:M04149 Factor: TFAP2B; motif: NGCCCNNRGGCA 0.0364054338791149 2351 97 22 0.22680412371134 0.00935772011909826
TF TF:M12017_1 Factor: TBR2; motif: NAGGTGTGAN; match class: 1 0.0365241879964651 58 86 3 0.0348837209302326 0.0517241379310345
TF TF:M00261 Factor: Olf-1; motif: NNCDABTCCCYAGRGARBNKGN 0.0365241879964651 3554 12 7 0.583333333333333 0.00196961170512099
TF TF:M07329 Factor: Osx; motif: CCNCCCCCNNN 0.0365241879964651 6803 60 32 0.533333333333333 0.0047038071439071
TF TF:M12136_1 Factor: mbnl2; motif: NYGCYTYGCYTN; match class: 1 0.0365337194475818 928 85 11 0.129411764705882 0.0118534482758621
TF TF:M11821 Factor: T3R-beta; motif: NTGACCTNACGTGACCTYA 0.0368755578349612 2526 48 14 0.291666666666667 0.00554235946159937
TF TF:M00033_1 Factor: p300; motif: NNNGGGAGTNNNNS; match class: 1 0.0368755578349612 2588 57 16 0.280701754385965 0.00618238021638331
TF TF:M08922 Factor: JUNB:FRA-1; motif: NNRTGACTCATNN 0.0374951729821481 1834 86 17 0.197674418604651 0.00926935659760087
TF TF:M03922_1 Factor: SP4; motif: NWRGCCACGCCCMCTYN; match class: 1 0.0381334974423528 2143 87 19 0.218390804597701 0.00886607559496034
TF TF:M00339 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS 0.0381366642881888 6806 13 10 0.769230769230769 0.00146929180135175
TF TF:M10055_1 Factor: RXR-alpha; motif: NNGNNRNNNARAGGTCANNG; match class: 1 0.0381366642881888 1082 96 13 0.135416666666667 0.0120147874306839
TF TF:M01173 Factor: SREBP-1; motif: NSNNTCACNCCANNN 0.0385943698546352 4810 82 32 0.390243902439024 0.00665280665280665
TF TF:M03551_1 Factor: JunB; motif: TGACTCAN; match class: 1 0.0385943698546352 599 45 6 0.133333333333333 0.010016694490818
TF TF:M02101 Factor: myogenin; motif: CAGCTG 0.0385943698546352 12960 86 69 0.802325581395349 0.00532407407407407
TF TF:M02101_1 Factor: myogenin; motif: CAGCTG; match class: 1 0.0385943698546352 12960 86 69 0.802325581395349 0.00532407407407407
TF TF:M12186 Factor: BTEB4; motif: NCCACGCCCM 0.0385943698546352 9135 76 48 0.631578947368421 0.00525451559934319
TF TF:M08389 Factor: MGA:pitx1; motif: AGGTGNTAAKCCN 0.0385943698546352 431 26 4 0.153846153846154 0.00928074245939675
TF TF:M02280_1 Factor: AP1; motif: TGACTCA; match class: 1 0.0385943698546352 599 45 6 0.133333333333333 0.010016694490818
TF TF:M06203_1 Factor: ZXDA; motif: NAGGGTG; match class: 1 0.0386542832767311 2007 93 19 0.204301075268817 0.00946686596910812
TF TF:M00647 Factor: LXR; motif: TGGGGTYACTNGCGGTCA 0.0386542832767311 2543 69 18 0.260869565217391 0.00707825403067243
TF TF:M00971 Factor: Ets; motif: ACTTCCTS 0.0386542832767311 2349 13 6 0.461538461538462 0.00255427841634738
TF TF:M00340 Factor: c-Ets; motif: KRCAGGAARTRNKT 0.0386542832767311 5402 30 16 0.533333333333333 0.00296186597556461
TF TF:M06202_1 Factor: ZXDB; motif: NAGGGTG; match class: 1 0.0386542832767311 2007 93 19 0.204301075268817 0.00946686596910812
TF TF:M07039 Factor: ETF; motif: CCCCGCCCCYN 0.0387716758434188 16384 66 63 0.954545454545455 0.00384521484375
TF TF:M00143_1 Factor: Pax-5; motif: BCNNNRNGCANBGNTGNRTAGCSGCHNB; match class: 1 0.0387716758434188 5086 63 27 0.428571428571429 0.00530869052300433
TF TF:M01801 Factor: ER-alpha; motif: AGGTCACNGTGACCT 0.0389426546751107 3396 26 11 0.423076923076923 0.00323910482921084
TF TF:M02114 Factor: pitx2; motif: NNTAAWCCCA 0.0389854485634849 4685 31 15 0.483870967741935 0.0032017075773746
TF TF:M07056 Factor: Pitx2; motif: WNTAAWCCCA 0.0389854485634849 4685 31 15 0.483870967741935 0.0032017075773746
TF TF:M09776 Factor: NEUROD1; motif: NNACAGATGGNNN 0.0389854485634849 919 13 4 0.307692307692308 0.0043525571273123
TF TF:M09826_1 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC; match class: 1 0.0389854485634849 7508 77 42 0.545454545454545 0.00559403303143314
TF TF:M03867 Factor: c-Myc; motif: CACGTGGC 0.0392060999456395 7391 87 46 0.528735632183908 0.00622378568529292
TF TF:M00221 Factor: SREBP-1; motif: KATCACCCCAC 0.039273673651285 7502 62 35 0.564516129032258 0.0046654225539856
TF TF:M00927_1 Factor: AP-4; motif: RNCAGCTGC; match class: 1 0.0392811931802849 1892 57 13 0.228070175438596 0.00687103594080338
TF TF:M04756_1 Factor: sin3A; motif: TGTCCNNGGTGCTG; match class: 1 0.0393713355854031 7714 86 47 0.546511627906977 0.00609281825252787
TF TF:M11218_1 Factor: CREB1; motif: NRTGAYGCGTN; match class: 1 0.0394105904943434 2438 21 8 0.380952380952381 0.00328137817883511
TF TF:M09622 Factor: GATA-2; motif: NSAGATAAGNN 0.0394503450888111 3044 5 4 0.8 0.00131406044678055
TF TF:M01841 Factor: ERR1; motif: NNYYMAAGGTCANGK 0.0394503450888111 1524 70 13 0.185714285714286 0.00853018372703412
TF TF:M09907 Factor: Erg; motif: NRRSAGGAAGNGG 0.0394963945810216 11682 28 24 0.857142857142857 0.00205444273240883
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.0394963945810216 10233 76 52 0.684210526315789 0.00508159874914492
TF TF:M11595 Factor: GCMa; motif: RTGCGGGTN 0.0394963945810216 12117 88 67 0.761363636363636 0.0055294214739622
TF TF:M03558_1 Factor: P73; motif: GNNNRRRCNTGCMNNTSASN; match class: 1 0.0399656335473647 822 98 11 0.112244897959184 0.01338199513382
TF TF:M09601 Factor: CTCFL; motif: YNNCCASYAGRKGGCRSYN 0.0399656335473647 367 74 6 0.0810810810810811 0.0163487738419619
TF TF:M10045_1 Factor: RAR-gamma; motif: RGGTCANNNTGNCCNNNN; match class: 1 0.0401799690401366 1965 49 12 0.244897959183673 0.00610687022900763
TF TF:M09923_1 Factor: Fra-2; motif: NNRTGAGTCAYN; match class: 1 0.0401799690401366 614 45 6 0.133333333333333 0.00977198697068404
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.0401799690401366 14096 77 66 0.857142857142857 0.00468217934165721
TF TF:M03914 Factor: KLF16; motif: GMCACGCCCCC 0.0407378998057628 3363 97 28 0.288659793814433 0.00832589949449896
TF TF:M08826 Factor: NF-E4; motif: GTGAGGS 0.0410165980164276 11318 87 63 0.724137931034483 0.00556635447959003
TF TF:M08872 Factor: DEC; motif: NNNSCACSTGAS 0.0410165980164276 7422 87 46 0.528735632183908 0.00619779035300458
TF TF:M00924_1 Factor: AP-1; motif: TGACTCANNSKN; match class: 1 0.0412231249313626 255 45 4 0.0888888888888889 0.0156862745098039
TF TF:M04953_1 Factor: Sp1; motif: GGNDGGRGGCGGGG; match class: 1 0.0412554488113215 4065 56 21 0.375 0.00516605166051661
TF TF:M00143 Factor: Pax-5; motif: BCNNNRNGCANBGNTGNRTAGCSGCHNB 0.0418476316097752 11392 82 60 0.731707317073171 0.00526685393258427
TF TF:M07103 Factor: JunB; motif: NRRTGASTCAK 0.0418476316097752 2383 86 20 0.232558139534884 0.00839278220730172
TF TF:M07406 Factor: SREBP-2; motif: RTGGGGTGAY 0.0420441693991264 5983 76 35 0.460526315789474 0.00584990807287314
TF TF:M00924 Factor: AP-1; motif: TGACTCANNSKN 0.0422641740876395 2801 74 20 0.27027027027027 0.00714030703320243
TF TF:M09915 Factor: PEA3; motif: NNCAGGAARNN 0.0422641740876395 12550 13 13 1 0.00103585657370518
TF TF:M03558 Factor: P73; motif: GNNNRRRCNTGCMNNTSASN 0.0422641740876395 4679 85 32 0.376470588235294 0.00683906817696089
TF TF:M05770 Factor: ZNFpT1; motif: GTWTTTTCGA 0.0424084965211653 117 48 3 0.0625 0.0256410256410256
TF TF:M08942 Factor: C-FOS:C-JUN; motif: ATGAGTCAYN 0.0424084965211653 3289 86 25 0.290697674418605 0.0076010945576163
TF TF:M09642 Factor: p53; motif: RGRCATGTCTGGRCATGYCN 0.0424084965211653 1620 91 16 0.175824175824176 0.00987654320987654
TF TF:M11828_1 Factor: LRH-1; motif: TCAAGGTCRYGACCTTGR; match class: 1 0.0424084965211653 7853 58 34 0.586206896551724 0.0043295555838533
TF TF:M00983 Factor: MAF; motif: NGCTGAGTCAN 0.0424084965211653 6031 73 34 0.465753424657534 0.00563753937987067
TF TF:M03906 Factor: HIC2; motif: RTGCCCRNN 0.0424084965211653 3458 82 25 0.304878048780488 0.00722961249277039
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.0424084965211653 10281 76 52 0.684210526315789 0.00505787374768991
TF TF:M09937 Factor: GATA-2; motif: NTGNNNNNNNNAGATAAGN 0.0424084965211653 2813 3 3 1 0.00106647707074298
TF TF:M03567_1 Factor: Sp2; motif: NYSGCCCCGCCCCCY; match class: 1 0.0424084965211653 3614 87 27 0.310344827586207 0.00747094631986718
TF TF:M01808_1 Factor: NMYC; motif: CAYCTG; match class: 1 0.0424084965211653 6149 44 23 0.522727272727273 0.00374044560091072
TF TF:M10014_1 Factor: FXR; motif: NRGGKCANTGRCCNNNNGG; match class: 1 0.0424084965211653 1498 98 16 0.163265306122449 0.0106809078771696
TF TF:M00665_1 Factor: Sp3; motif: ASMCTTGGGSRGGG; match class: 1 0.0425077532972832 2293 102 22 0.215686274509804 0.00959441779328391
TF TF:M10074_1 Factor: Spi-B; motif: NRAAAGAGGAAGTGARA; match class: 1 0.0426684527165394 75 75 3 0.04 0.04
TF TF:M00414 Factor: AREB6; motif: VNRCACCTGKNC 0.042693007381354 1767 62 13 0.209677419354839 0.00735710243350311
TF TF:M12158_1 Factor: KLF15; motif: NCCMCGCCCMCN; match class: 1 0.042693007381354 6004 76 35 0.460526315789474 0.00582944703530979
TF TF:M00199 Factor: AP-1; motif: NTGASTCAG 0.042693007381354 4833 86 33 0.383720930232558 0.00682805710738672
TF TF:M09658_1 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS; match class: 1 0.0429363732354823 2033 87 18 0.206896551724138 0.0088539104771274
TF TF:M01020_1 Factor: Tbx5; motif: TNAGGTGTKV; match class: 1 0.0429363732354823 4140 59 22 0.372881355932203 0.00531400966183575
TF TF:M01657 Factor: GLI3; motif: GTGGGTGGT 0.0432691397542691 1140 73 11 0.150684931506849 0.00964912280701754
TF TF:M03846_1 Factor: SMAD5; motif: GSGGCAGM; match class: 1 0.043496781405245 2502 100 23 0.23 0.00919264588329336
TF TF:M01655 Factor: p53; motif: GGACATGYYCGGACATGYYC 0.043496781405245 3419 92 27 0.293478260869565 0.00789704591985961
TF TF:M01109_1 Factor: SZF1-1; motif: CCAGGGTAWCAGCNG; match class: 1 0.0440239384595764 551 69 7 0.101449275362319 0.0127041742286751
TF TF:M07348 Factor: AP-2alpha; motif: NSCCNCRGGSN 0.0440239384595764 8047 17 13 0.764705882352941 0.00161550888529887
TF TF:M04632 Factor: SREBP-1; motif: NNNGTGGGGTGAN 0.0440239384595764 4860 73 29 0.397260273972603 0.00596707818930041
TF TF:M12157_1 Factor: KLF15; motif: RCCACGCCCCCC; match class: 1 0.0443192184871128 816 87 10 0.114942528735632 0.0122549019607843
TF TF:M01047_1 Factor: AP-2alphaA; motif: ANMGCCTNAGGCKNT; match class: 1 0.0443662354078147 9237 102 62 0.607843137254902 0.00671213597488362
TF TF:M01047 Factor: AP-2alphaA; motif: ANMGCCTNAGGCKNT 0.0443662354078147 9237 102 62 0.607843137254902 0.00671213597488362
TF TF:M09837_1 Factor: ZNF449; motif: NNNAGCCCARCC; match class: 1 0.0447401619789721 764 64 8 0.125 0.0104712041884817
TF TF:M03870 Factor: Fra-2; motif: TGASTCANCN 0.0447454140401712 3634 51 18 0.352941176470588 0.00495321959273528
TF TF:M09890 Factor: ctcf; motif: YGGCCACCAGRKGGCRSYN 0.0447535935800808 8479 78 46 0.58974358974359 0.00542516806227149
TF TF:M10075_1 Factor: SREBP-1; motif: NGTSRGGTGAN; match class: 1 0.0448791487604055 668 73 8 0.10958904109589 0.0119760479041916
TF TF:M08835_1 Factor: ZNF515; motif: WNSCCCCCWGCNG; match class: 1 0.0458381308245975 526 73 7 0.0958904109589041 0.0133079847908745
TF TF:M11492_1 Factor: LBP9; motif: ACYRGTNNNNACYRGT; match class: 1 0.0464601354012154 6005 98 43 0.438775510204082 0.00716069941715237
TF TF:M03893 Factor: WT1; motif: GNGGGGGCGGGG 0.0466036948517925 8290 98 55 0.561224489795918 0.00663449939686369
TF TF:M06948_1 Factor: Sp2; motif: TGGGCGCGCCCA; match class: 1 0.0469329024430472 6205 59 29 0.491525423728814 0.00467365028203062
TF TF:M11285 Factor: Fra-1; motif: GRTGACGTCATC 0.04715272753915 7708 27 18 0.666666666666667 0.00233523611831863
TF TF:M12135 Factor: mbnl2; motif: NYGCYTYGCTTN 0.0472489601957542 5855 49 24 0.489795918367347 0.00409906063193851
TF TF:M11765_1 Factor: TR2; motif: NRGGTCRYGACCYN; match class: 1 0.0472489601957542 1431 86 14 0.162790697674419 0.00978336827393431
TF TF:M07256_1 Factor: FXR:RXR; motif: RGGTCANTGACCTN; match class: 1 0.0472977751662144 122 49 3 0.0612244897959184 0.0245901639344262
TF TF:M08443_1 Factor: AP-4:ER81; motif: RSCGGAAGCAGSTGNN; match class: 1 0.0473348993576978 4014 65 23 0.353846153846154 0.0057299451918286
TF TF:M08920 Factor: JUNB:FOSB; motif: NRTGASTCAT 0.0475215377938984 3151 86 24 0.27906976744186 0.00761662964138369
TF TF:M00174 Factor: AP-1; motif: NNTGACTCANN 0.0476338053097642 1921 86 17 0.197674418604651 0.00884955752212389
TF TF:M07353 Factor: E2A; motif: CAGNTGNN 0.0479956613504137 2645 85 21 0.247058823529412 0.00793950850661626
TF TF:M07341 Factor: TORC2; motif: TGGGCTKKD 0.0481107023216226 4887 86 33 0.383720930232558 0.00675260896255371
TF TF:M03839 Factor: Pax-2; motif: CAYSCCTSAGT 0.0482258197443194 5052 50 22 0.44 0.00435471100554236
TF TF:M00513 Factor: ATF3; motif: CBCTGACGTCANCS 0.0483056023600209 6386 93 43 0.462365591397849 0.00673347948637645
TF TF:M01269 Factor: NURR1; motif: YRRCCTT 0.0484956454267994 5912 97 42 0.43298969072165 0.0071041948579161
TF TF:M03877 Factor: MASH-1; motif: YMMCACCTGCY 0.0484956454267994 1133 86 12 0.13953488372093 0.0105913503971756
TF TF:M00051 Factor: NF-kappaB; motif: GGGGATYCCC 0.0484956454267994 6413 60 30 0.5 0.00467799781693435
TF TF:M00033 Factor: p300; motif: NNNGGGAGTNNNNS 0.0485520197599643 8577 64 39 0.609375 0.00454704442112627
TF TF:M07387 Factor: LRF; motif: NGKGGGTSNCN 0.0489864638693361 5232 72 30 0.416666666666667 0.00573394495412844
TF TF:M00706 Factor: TFII-I; motif: RGAGGKAGG 0.0489864638693361 5714 86 37 0.430232558139535 0.00647532376618831
TF TF:M09916 Factor: Erm; motif: NRRSAGGAARNGRN 0.0489864638693361 6711 94 45 0.478723404255319 0.00670540902995083
TF TF:M09610_1 Factor: ER-beta; motif: NRGGTCANKSTGACCTNN; match class: 1 0.0489864638693361 1574 71 13 0.183098591549296 0.00825921219822109
TF TF:M07247 Factor: CLOCK; motif: CCACSTGW 0.0489864638693361 1953 45 11 0.244444444444444 0.00563236047107015
TF TF:M00411 Factor: HNF4alpha1; motif: NRGGNCAAAGGTCAN 0.0489884584628439 1811 84 16 0.19047619047619 0.00883489784649365
TF TF:M03807 Factor: SP2; motif: GNNGGGGGCGGGGSN 0.0491130348329044 8415 77 45 0.584415584415584 0.0053475935828877
TF TF:M01100 Factor: LRF; motif: GGGGKYNNB 0.0491130348329044 7557 78 42 0.538461538461538 0.0055577610162763
TF TF:M01801_1 Factor: ER-alpha; motif: AGGTCACNGTGACCT; match class: 1 0.0491130348329044 1922 22 7 0.318181818181818 0.0036420395421436
TF TF:M12340_1 Factor: BCL-6; motif: NCGYWATCTAGGAATN; match class: 1 0.0494101361872957 712 86 9 0.104651162790698 0.0126404494382022
TF TF:M09884 Factor: CLOCK; motif: CNGNCACGTGNNNM 0.0494101361872957 8420 87 50 0.574712643678161 0.00593824228028504
TF TF:M07129_1 Factor: Sp2; motif: GYCCCGCCYCYNNNN; match class: 1 0.0494101361872957 2422 87 20 0.229885057471264 0.00825763831544178
TF TF:M08870_1 Factor: DEC1; motif: NCNCACRTGNSC; match class: 1 0.0495065161104659 2440 58 15 0.258620689655172 0.00614754098360656
TF TF:M11830 Factor: LRH-1; motif: TGACCTTGRNYCAAGGTCA 0.049686195803406 7061 69 36 0.521739130434783 0.00509842798470472
TF TF:M09895 Factor: E2F-6; motif: NGGGCGGGARRNN 0.0498929278321328 7765 87 47 0.540229885057471 0.006052801030264
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 0.0499048514937347 6334 76 36 0.473684210526316 0.00568361225134196
TF TF:M11445_1 Factor: Elf-1; motif: NANCAGGAAGTR; match class: 1 0.0499048514937347 83 75 3 0.04 0.036144578313253

pEpiTd25 transcription factor target enrichment of top program genes

TF enrichment of pEpiTd25
Possible regulators of activation of pEpiTd25 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.