pEpi06 program activity among Epithelial cells

Activation of pEpi06
pEpi06 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpi06 by different cell subtypes
pEpi06 gene program activation among cells of different subtypes (Epithelial cells).

pEpi06 top program genes

Top genes of pEpi06 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpi06 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpi06
pEpi06 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:1990868 response to chemokine 3.6299043981088e-08 97 6 5 0.833333333333333 0.0515463917525773
GO:BP GO:1990869 cellular response to chemokine 3.6299043981088e-08 97 6 5 0.833333333333333 0.0515463917525773
GO:BP GO:0030595 leukocyte chemotaxis 1.0148455093885e-07 227 8 6 0.75 0.026431718061674
GO:BP GO:0071345 cellular response to cytokine stimulus 1.35328723084255e-07 1132 16 11 0.6875 0.00971731448763251
GO:BP GO:0030593 neutrophil chemotaxis 1.82374160100997e-07 103 8 5 0.625 0.0485436893203883
GO:BP GO:0034097 response to cytokine 2.12347308482214e-07 1226 16 11 0.6875 0.00897226753670473
GO:BP GO:0060326 cell chemotaxis 2.81759537315196e-07 310 8 6 0.75 0.0193548387096774
GO:BP GO:1990266 neutrophil migration 2.81759537315196e-07 124 8 5 0.625 0.0403225806451613
GO:BP GO:0071621 granulocyte chemotaxis 2.81759537315196e-07 126 8 5 0.625 0.0396825396825397
GO:BP GO:0097530 granulocyte migration 6.33111255784191e-07 151 8 5 0.625 0.033112582781457
GO:BP GO:0070098 chemokine-mediated signaling pathway 6.88537218550491e-07 87 5 4 0.8 0.0459770114942529
GO:BP GO:0019221 cytokine-mediated signaling pathway 1.50450957673339e-06 810 16 9 0.5625 0.0111111111111111
GO:BP GO:0050900 leukocyte migration 3.07230395329729e-06 511 8 6 0.75 0.0117416829745597
GO:BP GO:0097529 myeloid leukocyte migration 3.07230395329729e-06 221 8 5 0.625 0.0226244343891403
GO:BP GO:0006415 translational termination 9.63831100866141e-06 104 90 8 0.0888888888888889 0.0769230769230769
GO:BP GO:0006935 chemotaxis 1.0454779013551e-05 653 8 6 0.75 0.00918836140888208
GO:BP GO:0042330 taxis 1.0454779013551e-05 656 8 6 0.75 0.00914634146341463
GO:BP GO:0006412 translation 1.57331505615975e-05 764 67 15 0.223880597014925 0.0196335078534031
GO:BP GO:0070887 cellular response to chemical stimulus 2.18602504498099e-05 3393 23 16 0.695652173913043 0.00471559092248747
GO:BP GO:0043043 peptide biosynthetic process 2.18602504498099e-05 790 67 15 0.223880597014925 0.0189873417721519
GO:BP GO:0032543 mitochondrial translation 4.64249411224491e-05 136 88 8 0.0909090909090909 0.0588235294117647
GO:BP GO:0071310 cellular response to organic substance 0.000109737771327522 2776 23 14 0.608695652173913 0.00504322766570605
GO:BP GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 0.000114000920877441 81 5 3 0.6 0.037037037037037
GO:BP GO:0042254 ribosome biogenesis 0.000149058995422624 307 123 12 0.0975609756097561 0.0390879478827362
GO:BP GO:0043604 amide biosynthetic process 0.000149058995422624 932 67 15 0.223880597014925 0.0160944206008584
GO:BP GO:0043603 cellular amide metabolic process 0.000149397356624779 1241 52 15 0.288461538461538 0.0120870265914585
GO:BP GO:0140053 mitochondrial gene expression 0.000171888968578776 167 88 8 0.0909090909090909 0.0479041916167665
GO:BP GO:0006518 peptide metabolic process 0.000173486754865197 955 67 15 0.223880597014925 0.0157068062827225
GO:BP GO:0022613 ribonucleoprotein complex biogenesis 0.00021675594207687 446 123 14 0.113821138211382 0.031390134529148
GO:BP GO:0006396 RNA processing 0.00023699530355603 964 60 14 0.233333333333333 0.0145228215767635
GO:BP GO:0032496 response to lipopolysaccharide 0.000246924839299325 338 13 5 0.384615384615385 0.014792899408284
GO:BP GO:0010033 response to organic substance 0.00028651478924297 3412 24 15 0.625 0.00439624853458382
GO:BP GO:0002237 response to molecule of bacterial origin 0.000320233393722919 361 13 5 0.384615384615385 0.0138504155124654
GO:BP GO:0070125 mitochondrial translational elongation 0.000367072541941865 87 88 6 0.0681818181818182 0.0689655172413793
GO:BP GO:0071222 cellular response to lipopolysaccharide 0.000381108696030328 200 11 4 0.363636363636364 0.02
GO:BP GO:0070126 mitochondrial translational termination 0.000381108696030328 88 88 6 0.0681818181818182 0.0681818181818182
GO:BP GO:0034641 cellular nitrogen compound metabolic process 0.00038276347952219 6563 48 33 0.6875 0.0050281883285083
GO:BP GO:0019730 antimicrobial humoral response 0.00040031835084834 145 5 3 0.6 0.0206896551724138
GO:BP GO:0006414 translational elongation 0.000439338662971371 141 88 7 0.0795454545454545 0.049645390070922
GO:BP GO:0071219 cellular response to molecule of bacterial origin 0.00044853450842893 214 11 4 0.363636363636364 0.0186915887850467
GO:BP GO:0009617 response to bacterium 0.000467146624998629 743 13 6 0.461538461538462 0.00807537012113055
GO:BP GO:0042221 response to chemical 0.000491928487026396 4781 24 17 0.708333333333333 0.00355574147667852
GO:BP GO:0071216 cellular response to biotic stimulus 0.000635380952817691 238 11 4 0.363636363636364 0.0168067226890756
GO:BP GO:0007186 G protein-coupled receptor signaling pathway 0.000890872605061734 1355 6 5 0.833333333333333 0.003690036900369
GO:BP GO:0006959 humoral immune response 0.000890872605061734 384 8 4 0.5 0.0104166666666667
GO:BP GO:0016477 cell migration 0.0008949389444175 1649 8 6 0.75 0.00363856882959369
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 0.00097034165198843 5017 54 30 0.555555555555556 0.00597966912497508
GO:BP GO:0043624 cellular protein complex disassembly 0.00106497245633621 226 90 8 0.0888888888888889 0.0353982300884956
GO:BP GO:0006954 inflammatory response 0.0011055397072072 794 5 4 0.8 0.00503778337531486
GO:BP GO:0071396 cellular response to lipid 0.0011984243462885 578 19 6 0.315789473684211 0.0103806228373702
GO:BP GO:0033993 response to lipid 0.00126300503201713 918 13 6 0.461538461538462 0.0065359477124183
GO:BP GO:0051674 localization of cell 0.00134055468569499 1828 8 6 0.75 0.00328227571115974
GO:BP GO:0043207 response to external biotic stimulus 0.00134055468569499 1594 16 8 0.5 0.00501882057716437
GO:BP GO:0048870 cell motility 0.00134055468569499 1828 8 6 0.75 0.00328227571115974
GO:BP GO:0032984 protein-containing complex disassembly 0.00134055468569499 333 105 10 0.0952380952380952 0.03003003003003
GO:BP GO:0051707 response to other organism 0.00134055468569499 1592 16 8 0.5 0.0050251256281407
GO:BP GO:0022411 cellular component disassembly 0.00134197177079617 571 90 12 0.133333333333333 0.021015761821366
GO:BP GO:0002376 immune system process 0.00140831260214148 3278 12 9 0.75 0.00274557657107993
GO:BP GO:0009607 response to biotic stimulus 0.00143289619744063 1626 16 8 0.5 0.00492004920049201
GO:BP GO:0045638 negative regulation of myeloid cell differentiation 0.00146950510433633 94 12 3 0.25 0.0319148936170213
GO:BP GO:0006970 response to osmotic stress 0.00157031944706439 84 39 4 0.102564102564103 0.0476190476190476
GO:BP GO:0034470 ncRNA processing 0.00168231195022432 397 132 12 0.0909090909090909 0.0302267002518892
GO:BP GO:0045727 positive regulation of translation 0.00178399516150465 140 9 3 0.333333333333333 0.0214285714285714
GO:BP GO:0006950 response to stress 0.0019752430494932 4170 17 12 0.705882352941177 0.00287769784172662
GO:BP GO:0040011 locomotion 0.00211075604490764 2028 8 6 0.75 0.0029585798816568
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 0.00265204767648529 2255 24 11 0.458333333333333 0.0048780487804878
GO:BP GO:0071674 mononuclear cell migration 0.00284218896142383 191 8 3 0.375 0.0157068062827225
GO:BP GO:0034250 positive regulation of cellular amide metabolic process 0.00300037884681831 171 9 3 0.333333333333333 0.0175438596491228
GO:BP GO:0006364 rRNA processing 0.0041365115261865 224 60 6 0.1 0.0267857142857143
GO:BP GO:0006928 movement of cell or subcellular component 0.0041365115261865 2311 8 6 0.75 0.00259627866724362
GO:BP GO:0031328 positive regulation of cellular biosynthetic process 0.00441630775078764 1967 24 10 0.416666666666667 0.00508388408744281
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.00447770016628216 1227 13 6 0.461538461538462 0.00488997555012225
GO:BP GO:0034248 regulation of cellular amide metabolic process 0.00447770016628216 535 38 7 0.184210526315789 0.0130841121495327
GO:BP GO:0019827 stem cell population maintenance 0.00478498809037894 152 91 6 0.0659340659340659 0.0394736842105263
GO:BP GO:0016072 rRNA metabolic process 0.00484597552745751 234 60 6 0.1 0.0256410256410256
GO:BP GO:0009891 positive regulation of biosynthetic process 0.00484597552745751 2004 24 10 0.416666666666667 0.00499001996007984
GO:BP GO:0098727 maintenance of cell number 0.00488054682501797 154 91 6 0.0659340659340659 0.038961038961039
GO:BP GO:1901576 organic substance biosynthetic process 0.00488054682501797 6248 47 29 0.617021276595745 0.00464148527528809
GO:BP GO:0006195 purine nucleotide catabolic process 0.00579054103669401 47 40 3 0.075 0.0638297872340425
GO:BP GO:1901566 organonitrogen compound biosynthetic process 0.00607687174460847 1853 94 22 0.234042553191489 0.0118726389638424
GO:BP GO:0070371 ERK1 and ERK2 cascade 0.00611235561830198 329 16 4 0.25 0.0121580547112462
GO:BP GO:0009058 biosynthetic process 0.00616751189230984 6340 47 29 0.617021276595745 0.00457413249211357
GO:BP GO:0006417 regulation of translation 0.00637945617337597 462 12 4 0.333333333333333 0.00865800865800866
GO:BP GO:0042493 response to drug 0.00655407007345786 396 39 6 0.153846153846154 0.0151515151515152
GO:BP GO:0080134 regulation of response to stress 0.00664793697397221 1443 17 7 0.411764705882353 0.00485100485100485
GO:BP GO:0048662 negative regulation of smooth muscle cell proliferation 0.00708711443653215 70 30 3 0.1 0.0428571428571429
GO:BP GO:0072523 purine-containing compound catabolic process 0.00728727163754825 53 40 3 0.075 0.0566037735849057
GO:BP GO:0034660 ncRNA metabolic process 0.00872915680749352 493 132 12 0.0909090909090909 0.0243407707910751
GO:BP GO:0044249 cellular biosynthetic process 0.00922043107962014 6154 47 28 0.595744680851064 0.00454988625284368
GO:BP GO:0009605 response to external stimulus 0.00923115266636835 2944 13 8 0.615384615384615 0.00271739130434783
GO:BP GO:0006952 defense response 0.00956573499309039 1818 11 6 0.545454545454545 0.0033003300330033
GO:BP GO:0016071 mRNA metabolic process 0.00967393358790936 874 56 10 0.178571428571429 0.011441647597254
GO:BP GO:0006611 protein export from nucleus 0.0100036768862815 185 90 6 0.0666666666666667 0.0324324324324324
GO:BP GO:0009893 positive regulation of metabolic process 0.0103312664200101 3783 24 13 0.541666666666667 0.00343642611683849
GO:BP GO:0034645 cellular macromolecule biosynthetic process 0.0103588929970684 5051 26 16 0.615384615384615 0.00316768956642249
GO:BP GO:0010557 positive regulation of macromolecule biosynthetic process 0.0107561348273429 1851 24 9 0.375 0.00486223662884927
GO:BP GO:0006913 nucleocytoplasmic transport 0.0107561348273429 354 90 8 0.0888888888888889 0.0225988700564972
GO:BP GO:0006397 mRNA processing 0.0107561348273429 532 22 5 0.227272727272727 0.0093984962406015
GO:BP GO:0031325 positive regulation of cellular metabolic process 0.0107561348273429 3274 24 12 0.5 0.00366524129505192
GO:BP GO:0006725 cellular aromatic compound metabolic process 0.0107561348273429 5956 40 24 0.6 0.00402955003357958
GO:BP GO:0009059 macromolecule biosynthetic process 0.0110374382356774 5114 26 16 0.615384615384615 0.00312866640594447
GO:BP GO:0051169 nuclear transport 0.0110374382356774 357 90 8 0.0888888888888889 0.0224089635854342
GO:BP GO:0000096 sulfur amino acid metabolic process 0.0110942902857085 38 69 3 0.0434782608695652 0.0789473684210526
GO:BP GO:0045815 positive regulation of gene expression, epigenetic 0.0111112142747169 58 109 4 0.036697247706422 0.0689655172413793
GO:BP GO:0010608 posttranscriptional regulation of gene expression 0.0121308778584828 896 38 8 0.210526315789474 0.00892857142857143
GO:BP GO:2000036 regulation of stem cell population maintenance 0.0122090507078597 33 83 3 0.036144578313253 0.0909090909090909
GO:BP GO:0050658 RNA transport 0.0126983901281938 201 90 6 0.0666666666666667 0.0298507462686567
GO:BP GO:0050657 nucleic acid transport 0.0126983901281938 201 90 6 0.0666666666666667 0.0298507462686567
GO:BP GO:0045943 positive regulation of transcription by RNA polymerase I 0.0126983901281938 23 123 3 0.024390243902439 0.130434782608696
GO:BP GO:0051168 nuclear export 0.0133958041348935 204 90 6 0.0666666666666667 0.0294117647058824
GO:BP GO:0051236 establishment of RNA localization 0.0133958041348935 204 90 6 0.0666666666666667 0.0294117647058824
GO:BP GO:0008219 cell death 0.0134764299743705 2292 17 8 0.470588235294118 0.00349040139616056
GO:BP GO:0009166 nucleotide catabolic process 0.0134805271980649 73 40 3 0.075 0.0410958904109589
GO:BP GO:0010467 gene expression 0.0134805271980649 6179 25 17 0.68 0.00275125424826024
GO:BP GO:0071385 cellular response to glucocorticoid stimulus 0.0134805271980649 57 51 3 0.0588235294117647 0.0526315789473684
GO:BP GO:0010941 regulation of cell death 0.0135702384231557 1720 17 7 0.411764705882353 0.00406976744186047
GO:BP GO:0007166 cell surface receptor signaling pathway 0.0137804530722687 3210 16 9 0.5625 0.00280373831775701
GO:BP GO:0048585 negative regulation of response to stimulus 0.0138891492630016 1733 17 7 0.411764705882353 0.00403923831506059
GO:BP GO:0045637 regulation of myeloid cell differentiation 0.0139492193426715 263 12 3 0.25 0.0114068441064639
GO:BP GO:0044344 cellular response to fibroblast growth factor stimulus 0.0140009478618868 147 21 3 0.142857142857143 0.0204081632653061
GO:BP GO:0006139 nucleobase-containing compound metabolic process 0.0140009478618868 5746 40 23 0.575 0.00400278454577097
GO:BP GO:0062197 cellular response to chemical stress 0.0140009478618868 365 35 5 0.142857142857143 0.0136986301369863
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.0140334972356125 3483 24 12 0.5 0.00344530577088717
GO:BP GO:0048147 negative regulation of fibroblast proliferation 0.0145062567790495 34 93 3 0.032258064516129 0.0882352941176471
GO:BP GO:0051028 mRNA transport 0.0145062567790495 152 84 5 0.0595238095238095 0.0328947368421053
GO:BP GO:0071774 response to fibroblast growth factor 0.0145062567790495 153 21 3 0.142857142857143 0.0196078431372549
GO:BP GO:1901700 response to oxygen-containing compound 0.0147458285537437 1739 13 6 0.461538461538462 0.00345025876940771
GO:BP GO:0071384 cellular response to corticosteroid stimulus 0.0147458285537437 63 51 3 0.0588235294117647 0.0476190476190476
GO:BP GO:1901360 organic cyclic compound metabolic process 0.0147707966723904 6201 40 24 0.6 0.003870343492985
GO:BP GO:0050793 regulation of developmental process 0.0154948448628128 2605 16 8 0.5 0.00307101727447217
GO:BP GO:0016070 RNA metabolic process 0.0155396304606793 4710 24 14 0.583333333333333 0.0029723991507431
GO:BP GO:0051179 localization 0.0156697139411951 6901 13 11 0.846153846153846 0.00159397188813215
GO:BP GO:0042127 regulation of cell population proliferation 0.0157534608544184 1774 13 6 0.461538461538462 0.00338218714768884
GO:BP GO:1901292 nucleoside phosphate catabolic process 0.0160785835131868 84 40 3 0.075 0.0357142857142857
GO:BP GO:0006915 apoptotic process 0.0168184561635335 1990 16 7 0.4375 0.00351758793969849
GO:BP GO:0071356 cellular response to tumor necrosis factor 0.0175396756798447 306 12 3 0.25 0.00980392156862745
GO:BP GO:0090304 nucleic acid metabolic process 0.0175396756798447 5226 27 16 0.592592592592593 0.00306161500191351
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.0178042911145709 3083 24 11 0.458333333333333 0.00356795329224781
GO:BP GO:0006368 transcription elongation from RNA polymerase II promoter 0.0178849081812856 88 91 4 0.043956043956044 0.0454545454545455
GO:BP GO:0046483 heterocycle metabolic process 0.0178849081812856 5904 40 23 0.575 0.00389566395663957
GO:BP GO:0051384 response to glucocorticoid 0.0188083676901598 146 56 4 0.0714285714285714 0.0273972602739726
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.0196601028857978 549 16 4 0.25 0.00728597449908925
GO:BP GO:0051254 positive regulation of RNA metabolic process 0.0199067928911809 1714 24 8 0.333333333333333 0.00466744457409568
GO:BP GO:2000112 regulation of cellular macromolecule biosynthetic process 0.0199154962960296 4071 25 13 0.52 0.00319331859493982
GO:BP GO:0034612 response to tumor necrosis factor 0.0199154962960296 331 12 3 0.25 0.00906344410876133
GO:BP GO:0006955 immune response 0.0199154962960296 2311 5 4 0.8 0.00173085244482908
GO:BP GO:0006360 transcription by RNA polymerase I 0.0199154962960296 68 123 4 0.032520325203252 0.0588235294117647
GO:BP GO:0035556 intracellular signal transduction 0.0199544994369944 2772 16 8 0.5 0.00288600288600289
GO:BP GO:0006403 RNA localization 0.0199544994369944 238 90 6 0.0666666666666667 0.0252100840336134
GO:BP GO:0008283 cell population proliferation 0.019967768739641 2054 30 10 0.333333333333333 0.00486854917234664
GO:BP GO:0007165 signal transduction 0.020021558361882 6309 16 12 0.75 0.0019020446980504
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0203122455378304 2541 25 10 0.4 0.00393545848091303
GO:BP GO:0010556 regulation of macromolecule biosynthetic process 0.0205708285240971 4102 25 13 0.52 0.00316918576304242
GO:BP GO:0009628 response to abiotic stimulus 0.0207555680135133 1261 13 5 0.384615384615385 0.00396510705789056
GO:BP GO:0012501 programmed cell death 0.0213455063008603 2143 16 7 0.4375 0.00326644890340644
GO:BP GO:0016032 viral process 0.0213455063008603 942 108 14 0.12962962962963 0.0148619957537155
GO:BP GO:0042981 regulation of apoptotic process 0.021634818820336 1549 16 6 0.375 0.00387346675274371
GO:BP GO:0006366 transcription by RNA polymerase II 0.0219650857360194 2723 24 10 0.416666666666667 0.00367242012486228
GO:BP GO:0033554 cellular response to stress 0.0219650857360194 2111 30 10 0.333333333333333 0.00473709142586452
GO:BP GO:0045595 regulation of cell differentiation 0.0219730856635327 1679 15 6 0.4 0.00357355568790947
GO:BP GO:0006356 regulation of transcription by RNA polymerase I 0.0223400299745887 34 123 3 0.024390243902439 0.0882352941176471
GO:BP GO:0043067 regulation of programmed cell death 0.0231466592993056 1582 16 6 0.375 0.00379266750948167
GO:BP GO:0031960 response to corticosteroid 0.023590690363055 165 56 4 0.0714285714285714 0.0242424242424242
GO:BP GO:0015931 nucleobase-containing compound transport 0.0256902278990995 260 90 6 0.0666666666666667 0.0230769230769231
GO:BP GO:0031326 regulation of cellular biosynthetic process 0.025890724808843 4273 25 13 0.52 0.00304235899836181
GO:BP GO:0031058 positive regulation of histone modification 0.025890724808843 91 105 4 0.0380952380952381 0.043956043956044
GO:BP GO:0051246 regulation of protein metabolic process 0.0261823280948963 2704 25 10 0.4 0.00369822485207101
GO:BP GO:0060548 negative regulation of cell death 0.0261823280948963 1038 17 5 0.294117647058824 0.00481695568400771
GO:BP GO:0009066 aspartate family amino acid metabolic process 0.0261823280948963 49 94 3 0.0319148936170213 0.0612244897959184
GO:BP GO:0001666 response to hypoxia 0.0261823280948963 367 13 3 0.230769230769231 0.00817438692098093
GO:BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process 0.0262291658911289 1887 24 8 0.333333333333333 0.00423953365129836
GO:BP GO:0034404 nucleobase-containing small molecule biosynthetic process 0.0262291658911289 117 40 3 0.075 0.0256410256410256
GO:BP GO:0030099 myeloid cell differentiation 0.0265448354637804 428 24 4 0.166666666666667 0.00934579439252336
GO:BP GO:0048522 positive regulation of cellular process 0.0267185553353748 5757 38 21 0.552631578947368 0.00364773319437207
GO:BP GO:0070848 response to growth factor 0.0267185553353748 759 23 5 0.217391304347826 0.00658761528326746
GO:BP GO:0036293 response to decreased oxygen levels 0.0267185553353748 382 13 3 0.230769230769231 0.00785340314136126
GO:BP GO:0009889 regulation of biosynthetic process 0.0268686568615487 4361 25 13 0.52 0.00298096766796606
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.0271778894730305 1477 24 7 0.291666666666667 0.004739336492891
GO:BP GO:1903706 regulation of hemopoiesis 0.0273612264066166 424 12 3 0.25 0.00707547169811321
GO:BP GO:0009611 response to wounding 0.0275335974954841 674 16 4 0.25 0.00593471810089021
GO:BP GO:0044403 biological process involved in symbiotic interaction 0.0279283904531079 1001 108 14 0.12962962962963 0.013986013986014
GO:BP GO:0002685 regulation of leukocyte migration 0.0291207378591761 211 24 3 0.125 0.014218009478673
GO:BP GO:0002682 regulation of immune system process 0.0291207378591761 1617 12 5 0.416666666666667 0.00309214594928881
GO:BP GO:0023052 signaling 0.0291207378591761 6810 16 12 0.75 0.00176211453744493
GO:BP GO:1903793 positive regulation of anion transport 0.0291257510697112 504 35 5 0.142857142857143 0.00992063492063492
GO:BP GO:0002573 myeloid leukocyte differentiation 0.0294807431021294 213 24 3 0.125 0.0140845070422535
GO:BP GO:0007154 cell communication 0.0296176906164863 6829 16 12 0.75 0.00175721189046713
GO:BP GO:0070482 response to oxygen levels 0.0296844215663311 408 13 3 0.230769230769231 0.00735294117647059
GO:BP GO:0006354 DNA-templated transcription, elongation 0.0305157112712445 117 91 4 0.043956043956044 0.0341880341880342
GO:BP GO:0051204 protein insertion into mitochondrial membrane 0.0305157112712445 48 107 3 0.0280373831775701 0.0625
GO:BP GO:0048660 regulation of smooth muscle cell proliferation 0.0308784171547299 174 30 3 0.1 0.0172413793103448
GO:BP GO:0051093 negative regulation of developmental process 0.0309209907257444 977 12 4 0.333333333333333 0.00409416581371546
GO:BP GO:0043462 regulation of ATPase activity 0.0312196171666287 80 65 3 0.0461538461538462 0.0375
GO:BP GO:0006606 protein import into nucleus 0.0315078660973504 152 35 3 0.0857142857142857 0.0197368421052632
GO:BP GO:0048659 smooth muscle cell proliferation 0.0315078660973504 176 30 3 0.1 0.0170454545454545
GO:BP GO:0048518 positive regulation of biological process 0.0315078660973504 6363 25 16 0.64 0.00251453716800251
GO:BP GO:0034599 cellular response to oxidative stress 0.0315078660973504 316 35 4 0.114285714285714 0.0126582278481013
GO:BP GO:0009411 response to UV 0.0315078660973504 151 35 3 0.0857142857142857 0.0198675496688742
GO:BP GO:0050729 positive regulation of inflammatory response 0.0317028601948081 142 77 4 0.051948051948052 0.028169014084507
GO:BP GO:1905269 positive regulation of chromatin organization 0.0325809188630639 105 105 4 0.0380952380952381 0.0380952380952381
GO:BP GO:0051247 positive regulation of protein metabolic process 0.0327514814774947 1564 24 7 0.291666666666667 0.00447570332480818
GO:BP GO:0001701 in utero embryonic development 0.0328863626631952 365 122 8 0.0655737704918033 0.0219178082191781
GO:BP GO:1902531 regulation of intracellular signal transduction 0.0341158848800712 1842 16 6 0.375 0.00325732899022801
GO:BP GO:0008285 negative regulation of cell population proliferation 0.0345329401645041 790 35 6 0.171428571428571 0.00759493670886076
GO:BP GO:0010468 regulation of gene expression 0.0349814959931631 5196 25 14 0.56 0.00269438029253272
GO:BP GO:0006357 regulation of transcription by RNA polymerase II 0.0349814959931631 2555 24 9 0.375 0.00352250489236791
GO:BP GO:0090151 establishment of protein localization to mitochondrial membrane 0.0349814959931631 53 107 3 0.0280373831775701 0.0566037735849057
GO:BP GO:0045944 positive regulation of transcription by RNA polymerase II 0.0349814959931631 1197 24 6 0.25 0.0050125313283208
GO:BP GO:1903508 positive regulation of nucleic acid-templated transcription 0.0349814959931631 1617 24 7 0.291666666666667 0.00432900432900433
GO:BP GO:1902680 positive regulation of RNA biosynthetic process 0.0349814959931631 1618 24 7 0.291666666666667 0.00432632880098887
GO:BP GO:0045893 positive regulation of transcription, DNA-templated 0.0349814959931631 1617 24 7 0.291666666666667 0.00432900432900433
GO:BP GO:0080135 regulation of cellular response to stress 0.0350377111082734 725 17 4 0.235294117647059 0.00551724137931034
GO:BP GO:0071426 ribonucleoprotein complex export from nucleus 0.0351921722688009 130 90 4 0.0444444444444444 0.0307692307692308
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 0.0354064679799439 167 35 3 0.0857142857142857 0.0179640718562874
GO:BP GO:0071166 ribonucleoprotein complex localization 0.0359593656553207 131 90 4 0.0444444444444444 0.0305343511450382
GO:BP GO:0044282 small molecule catabolic process 0.0365297121330873 439 129 9 0.0697674418604651 0.020501138952164
GO:BP GO:0006400 tRNA modification 0.0366342561217561 90 132 4 0.0303030303030303 0.0444444444444444
GO:BP GO:0051170 import into nucleus 0.0367382646200351 172 35 3 0.0857142857142857 0.0174418604651163
GO:BP GO:0006405 RNA export from nucleus 0.0367382646200351 143 135 5 0.037037037037037 0.034965034965035
GO:BP GO:0071346 cellular response to interferon-gamma 0.0370490659601111 175 35 3 0.0857142857142857 0.0171428571428571
GO:BP GO:0033077 T cell differentiation in thymus 0.0370490659601111 76 80 3 0.0375 0.0394736842105263
GO:BP GO:0006351 transcription, DNA-templated 0.0370490659601111 3714 24 11 0.458333333333333 0.00296176628971459
GO:BP GO:0097659 nucleic acid-templated transcription 0.0370490659601111 3715 24 11 0.458333333333333 0.00296096904441454
GO:BP GO:0019439 aromatic compound catabolic process 0.0373422962125216 623 46 6 0.130434782608696 0.00963081861958266
GO:BP GO:0032774 RNA biosynthetic process 0.0377274697339201 3731 24 11 0.458333333333333 0.00294827124095417
GO:BP GO:1903749 positive regulation of establishment of protein localization to mitochondrion 0.0381041179783819 58 107 3 0.0280373831775701 0.0517241379310345
GO:BP GO:0090316 positive regulation of intracellular protein transport 0.038182518431437 186 107 5 0.0467289719626168 0.0268817204301075
GO:BP GO:0046434 organophosphate catabolic process 0.0382151862365222 157 40 3 0.075 0.0191082802547771
GO:BP GO:0043933 protein-containing complex subunit organization 0.0382151862365222 1963 107 21 0.196261682242991 0.010697911360163
GO:BP GO:0009968 negative regulation of signal transduction 0.0393168229783583 1364 16 5 0.3125 0.00366568914956012
GO:BP GO:0034654 nucleobase-containing compound biosynthetic process 0.0393168229783583 4199 40 17 0.425 0.00404858299595142
GO:BP GO:0051716 cellular response to stimulus 0.0396476217280858 7781 17 13 0.764705882352941 0.0016707364092019
GO:BP GO:0045785 positive regulation of cell adhesion 0.0410264400271157 437 30 4 0.133333333333333 0.0091533180778032
GO:BP GO:1901361 organic cyclic compound catabolic process 0.0416139283672732 651 46 6 0.130434782608696 0.00921658986175115
GO:BP GO:0051252 regulation of RNA metabolic process 0.0416139283672732 3822 24 11 0.458333333333333 0.00287807430664574
GO:BP GO:0018130 heterocycle biosynthetic process 0.0426619268351058 4269 40 17 0.425 0.00398219723588662
GO:BP GO:0071897 DNA biosynthetic process 0.0427709812189307 195 35 3 0.0857142857142857 0.0153846153846154
GO:BP GO:0019438 aromatic compound biosynthetic process 0.0428596440530236 4278 40 17 0.425 0.00397381954184198
GO:BP GO:0034341 response to interferon-gamma 0.0428596440530236 196 35 3 0.0857142857142857 0.0153061224489796
GO:BP GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 0.0436419997478399 198 35 3 0.0857142857142857 0.0151515151515152
GO:BP GO:0009117 nucleotide metabolic process 0.0436562644382309 544 40 5 0.125 0.00919117647058824
GO:BP GO:0000165 MAPK cascade 0.0445798795766605 935 24 5 0.208333333333333 0.0053475935828877
GO:BP GO:0006807 nitrogen compound metabolic process 0.0448059716060886 10078 38 29 0.763157894736842 0.00287755507045049
GO:BP GO:0030335 positive regulation of cell migration 0.0450816729418816 567 13 3 0.230769230769231 0.00529100529100529
GO:BP GO:0006753 nucleoside phosphate metabolic process 0.0454146182780956 555 40 5 0.125 0.00900900900900901
GO:BP GO:0017038 protein import 0.0454146182780956 205 106 5 0.0471698113207547 0.024390243902439
GO:BP GO:0019637 organophosphate metabolic process 0.0454146182780956 1041 40 7 0.175 0.00672430355427474
GO:BP GO:0023057 negative regulation of signaling 0.0454146182780956 1471 16 5 0.3125 0.00339904826648538
GO:BP GO:0010648 negative regulation of cell communication 0.0454146182780956 1468 16 5 0.3125 0.00340599455040872
GO:BP GO:0010628 positive regulation of gene expression 0.0454146182780956 1160 45 8 0.177777777777778 0.00689655172413793
GO:BP GO:0043066 negative regulation of apoptotic process 0.0461418771711358 921 16 4 0.25 0.00434310532030402
GO:BP GO:0033002 muscle cell proliferation 0.0462409963024415 244 30 3 0.1 0.0122950819672131
GO:BP GO:0072594 establishment of protein localization to organelle 0.046741151708078 584 107 9 0.0841121495327103 0.0154109589041096
GO:BP GO:2000147 positive regulation of cell motility 0.0467646459465267 591 13 3 0.230769230769231 0.0050761421319797
GO:BP GO:0009451 RNA modification 0.0468701732387053 168 132 5 0.0378787878787879 0.0297619047619048
GO:BP GO:0006413 translational initiation 0.0470582223234865 201 111 5 0.045045045045045 0.0248756218905473
GO:BP GO:0071456 cellular response to hypoxia 0.0470582223234865 212 35 3 0.0857142857142857 0.0141509433962264
GO:BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 0.0471229130593767 361 21 3 0.142857142857143 0.00831024930747922
GO:BP GO:0000398 mRNA splicing, via spliceosome 0.0471229130593767 361 21 3 0.142857142857143 0.00831024930747922
GO:BP GO:0043069 negative regulation of programmed cell death 0.0472328887542791 943 16 4 0.25 0.00424178154825027
GO:BP GO:0000375 RNA splicing, via transesterification reactions 0.0478352628981389 364 21 3 0.142857142857143 0.00824175824175824
GO:BP GO:0044770 cell cycle phase transition 0.0478366318371603 658 35 5 0.142857142857143 0.00759878419452888
GO:BP GO:0051272 positive regulation of cellular component movement 0.0478604479882458 604 13 3 0.230769230769231 0.00496688741721854
GO:BP GO:0040017 positive regulation of locomotion 0.0481149243800733 606 13 3 0.230769230769231 0.00495049504950495
GO:BP GO:1901575 organic substance catabolic process 0.0483153036915795 2267 40 11 0.275 0.00485222761358624
GO:BP GO:1901565 organonitrogen compound catabolic process 0.0490048671377302 1358 40 8 0.2 0.00589101620029455
GO:CC GO:0005730 nucleolus 1.31219443495123e-07 955 123 26 0.211382113821138 0.0272251308900524
GO:CC GO:0005739 mitochondrion 1.35773859374638e-06 1673 132 34 0.257575757575758 0.0203227734608488
GO:CC GO:0005759 mitochondrial matrix 3.20928905131144e-06 479 129 17 0.131782945736434 0.0354906054279749
GO:CC GO:1990904 ribonucleoprotein complex 6.15743730281818e-05 688 67 13 0.194029850746269 0.0188953488372093
GO:CC GO:0005840 ribosome 0.00014275891566972 245 88 9 0.102272727272727 0.036734693877551
GO:CC GO:0005761 mitochondrial ribosome 0.000168027232832112 88 88 6 0.0681818181818182 0.0681818181818182
GO:CC GO:0000313 organellar ribosome 0.000168027232832112 88 88 6 0.0681818181818182 0.0681818181818182
GO:CC GO:0000315 organellar large ribosomal subunit 0.000258551615056516 57 88 5 0.0568181818181818 0.087719298245614
GO:CC GO:0005762 mitochondrial large ribosomal subunit 0.000258551615056516 57 88 5 0.0568181818181818 0.087719298245614
GO:CC GO:0043228 non-membrane-bounded organelle 0.000373458246807902 5346 70 37 0.528571428571429 0.00692106247661803
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.000373458246807902 5338 70 37 0.528571428571429 0.00693143499437992
GO:CC GO:0015934 large ribosomal subunit 0.000533317591029992 118 88 6 0.0681818181818182 0.0508474576271186
GO:CC GO:0005740 mitochondrial envelope 0.000571490741653209 797 126 17 0.134920634920635 0.0213299874529486
GO:CC GO:0031966 mitochondrial membrane 0.0008863134570309 746 126 16 0.126984126984127 0.0214477211796247
GO:CC GO:0031975 envelope 0.00126346245338938 1237 107 19 0.177570093457944 0.01535974130962
GO:CC GO:0031967 organelle envelope 0.00126346245338938 1237 107 19 0.177570093457944 0.01535974130962
GO:CC GO:0001650 fibrillar center 0.00171472088676803 141 60 5 0.0833333333333333 0.0354609929078014
GO:CC GO:0019866 organelle inner membrane 0.00191581248577372 564 126 13 0.103174603174603 0.0230496453900709
GO:CC GO:0070013 intracellular organelle lumen 0.00202600035302974 5402 135 59 0.437037037037037 0.0109218807848945
GO:CC GO:0031974 membrane-enclosed lumen 0.0021494000610837 5565 135 60 0.444444444444444 0.0107816711590297
GO:CC GO:0005743 mitochondrial inner membrane 0.0021494000610837 503 126 12 0.0952380952380952 0.0238568588469185
GO:CC GO:0043233 organelle lumen 0.0021494000610837 5565 135 60 0.444444444444444 0.0107816711590297
GO:CC GO:0044391 ribosomal subunit 0.00374205741706797 190 88 6 0.0681818181818182 0.0315789473684211
GO:CC GO:0031981 nuclear lumen 0.00374205741706797 4444 46 22 0.478260869565217 0.00495049504950495
GO:CC GO:0005654 nucleoplasm 0.00763245518339217 4102 135 46 0.340740740740741 0.0112140419307655
GO:CC GO:0098798 mitochondrial protein-containing complex 0.0100897336962147 270 106 7 0.0660377358490566 0.0259259259259259
GO:CC GO:0005615 extracellular space 0.0106079143078887 3594 8 6 0.75 0.00166944908180301
GO:CC GO:0043229 intracellular organelle 0.0110150954835812 12491 116 92 0.793103448275862 0.00736530301817308
GO:CC GO:0016591 RNA polymerase II, holoenzyme 0.0110150954835812 92 91 4 0.043956043956044 0.0434782608695652
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.0141291413707789 11296 116 85 0.732758620689655 0.00752478753541076
GO:CC GO:0000428 DNA-directed RNA polymerase complex 0.0209336389945653 118 91 4 0.043956043956044 0.0338983050847458
GO:CC GO:0055029 nuclear DNA-directed RNA polymerase complex 0.0209336389945653 117 91 4 0.043956043956044 0.0341880341880342
GO:CC GO:0016323 basolateral plasma membrane 0.02175725977377 222 24 3 0.125 0.0135135135135135
GO:CC GO:0030880 RNA polymerase complex 0.0220133880959436 122 91 4 0.043956043956044 0.0327868852459016
GO:CC GO:0009925 basal plasma membrane 0.0245410486810399 247 24 3 0.125 0.0121457489878543
GO:CC GO:0005634 nucleus 0.0245410486810399 7592 42 26 0.619047619047619 0.00342465753424658
GO:CC GO:0005576 extracellular region 0.0245410486810399 4567 8 6 0.75 0.0013137727173199
GO:CC GO:0005622 intracellular anatomical structure 0.0245410486810399 14790 135 118 0.874074074074074 0.00797836375929682
GO:CC GO:0045178 basal part of cell 0.0285004905981831 265 24 3 0.125 0.0113207547169811
GO:CC GO:0005791 rough endoplasmic reticulum 0.0306011481656153 86 75 3 0.04 0.0348837209302326
GO:CC GO:0005925 focal adhesion 0.0368352048251509 420 53 5 0.0943396226415094 0.0119047619047619
GO:CC GO:0030055 cell-substrate junction 0.0377569453279196 427 53 5 0.0943396226415094 0.0117096018735363
GO:CC GO:0140513 nuclear protein-containing complex 0.0385230940330169 1249 35 7 0.2 0.0056044835868695
GO:CC GO:0140535 intracellular protein-containing complex 0.0409947624165407 767 117 11 0.094017094017094 0.0143415906127771
GO:CC GO:0005829 cytosol 0.0409947624165407 5303 46 21 0.456521739130435 0.00396002262870074
GO:MF GO:0008009 chemokine activity 1.03492915944126e-07 49 5 4 0.8 0.0816326530612245
GO:MF GO:0042379 chemokine receptor binding 2.51013217279435e-07 72 5 4 0.8 0.0555555555555556
GO:MF GO:0045236 CXCR chemokine receptor binding 1.24135654932269e-06 18 5 3 0.6 0.166666666666667
GO:MF GO:0001664 G protein-coupled receptor binding 6.03386350506652e-06 292 8 5 0.625 0.0171232876712329
GO:MF GO:0003723 RNA binding 9.36827916849872e-06 1943 52 20 0.384615384615385 0.0102933607822954
GO:MF GO:0005125 cytokine activity 1.00025891197272e-05 235 5 4 0.8 0.0170212765957447
GO:MF GO:0005126 cytokine receptor binding 1.61101816913838e-05 275 5 4 0.8 0.0145454545454545
GO:MF GO:0030515 snoRNA binding 6.24060661572272e-05 32 45 4 0.0888888888888889 0.125
GO:MF GO:0030546 signaling receptor activator activity 0.000124235485080246 501 5 4 0.8 0.00798403193612774
GO:MF GO:0048018 receptor ligand activity 0.000124235485080246 494 5 4 0.8 0.00809716599190283
GO:MF GO:0030545 receptor regulator activity 0.000158005619579589 545 5 4 0.8 0.0073394495412844
GO:MF GO:0003676 nucleic acid binding 0.000499371505273436 4276 54 27 0.5 0.00631431244153414
GO:MF GO:0097159 organic cyclic compound binding 0.00413520952753082 6309 54 32 0.592592592592593 0.00507211919480108
GO:MF GO:0003735 structural constituent of ribosome 0.00548082554475379 171 88 6 0.0681818181818182 0.0350877192982456
GO:MF GO:0017069 snRNA binding 0.00572140536467601 46 45 3 0.0666666666666667 0.0652173913043478
GO:MF GO:1901363 heterocyclic compound binding 0.00670259850592098 6228 54 31 0.574074074074074 0.00497752087347463
GO:MF GO:0005102 signaling receptor binding 0.00670259850592098 1672 8 5 0.625 0.00299043062200957
GO:MF GO:0001099 basal RNA polymerase II transcription machinery binding 0.00772051914860033 69 91 4 0.043956043956044 0.0579710144927536
GO:MF GO:0090079 translation regulator activity, nucleic acid binding 0.00772051914860033 123 51 4 0.0784313725490196 0.032520325203252
GO:MF GO:0001098 basal transcription machinery binding 0.00772051914860033 69 91 4 0.043956043956044 0.0579710144927536
GO:MF GO:0045182 translation regulator activity 0.0169940301220541 155 51 4 0.0784313725490196 0.0258064516129032
GO:MF GO:0140101 catalytic activity, acting on a tRNA 0.018394398110863 130 111 5 0.045045045045045 0.0384615384615385
GO:MF GO:0098772 molecular function regulator 0.0190025303875243 2363 5 4 0.8 0.00169276343630978
GO:MF GO:0019843 rRNA binding 0.0204025478858733 63 64 3 0.046875 0.0476190476190476
GO:MF GO:0000993 RNA polymerase II complex binding 0.0220376134121436 50 91 3 0.032967032967033 0.06
GO:MF GO:0001046 core promoter sequence-specific DNA binding 0.0220376134121436 43 105 3 0.0285714285714286 0.0697674418604651
GO:MF GO:0019899 enzyme binding 0.0220376134121436 2074 22 8 0.363636363636364 0.0038572806171649
GO:MF GO:0044877 protein-containing complex binding 0.0226470885601007 1287 35 8 0.228571428571429 0.00621600621600622
GO:MF GO:0043175 RNA polymerase core enzyme binding 0.0243348806193799 55 91 3 0.032967032967033 0.0545454545454545
GO:MF GO:0008135 translation factor activity, RNA binding 0.0243348806193799 99 51 3 0.0588235294117647 0.0303030303030303
GO:MF GO:0140098 catalytic activity, acting on RNA 0.0243348806193799 395 111 8 0.0720720720720721 0.020253164556962
GO:MF GO:0008134 transcription factor binding 0.0260015065498773 676 17 4 0.235294117647059 0.00591715976331361
GO:MF GO:0042802 identical protein binding 0.0260473626781398 2067 45 12 0.266666666666667 0.0058055152394775
GO:MF GO:0140297 DNA-binding transcription factor binding 0.0289306581735645 391 51 5 0.0980392156862745 0.0127877237851662
GO:MF GO:0003729 mRNA binding 0.0294340609886041 552 12 3 0.25 0.00543478260869565
GO:MF GO:0070063 RNA polymerase binding 0.0316746873643059 72 91 3 0.032967032967033 0.0416666666666667
GO:MF GO:0051087 chaperone binding 0.032036429723976 103 65 3 0.0461538461538462 0.029126213592233
GO:MF GO:0003712 transcription coregulator activity 0.0397422975259357 506 109 8 0.073394495412844 0.0158102766798419
GO:MF GO:0005198 structural molecule activity 0.04890626972223 698 100 9 0.09 0.0128939828080229
KEGG KEGG:04061 Viral protein interaction with cytokine and cytokine receptor 5.38279130740196e-06 98 5 4 0.8 0.0408163265306122
KEGG KEGG:05323 Rheumatoid arthritis 5.38279130740196e-06 88 5 4 0.8 0.0454545454545455
KEGG KEGG:04657 IL-17 signaling pathway 5.38279130740196e-06 92 11 5 0.454545454545455 0.0543478260869565
KEGG KEGG:04668 TNF signaling pathway 6.93141486409964e-06 112 5 4 0.8 0.0357142857142857
KEGG KEGG:05134 Legionellosis 2.26713378448023e-05 57 11 4 0.363636363636364 0.0701754385964912
KEGG KEGG:05120 Epithelial cell signaling in Helicobacter pylori infection 3.72467305987887e-05 70 11 4 0.363636363636364 0.0571428571428571
KEGG KEGG:04062 Chemokine signaling pathway 3.72467305987887e-05 190 5 4 0.8 0.0210526315789474
KEGG KEGG:05167 Kaposi sarcoma-associated herpesvirus infection 6.13056534726704e-05 193 11 5 0.454545454545455 0.0259067357512953
KEGG KEGG:04064 NF-kappa B signaling pathway 0.00013127279393016 102 11 4 0.363636363636364 0.0392156862745098
KEGG KEGG:04060 Cytokine-cytokine receptor interaction 0.000131837796401285 293 5 4 0.8 0.0136518771331058
KEGG KEGG:05146 Amoebiasis 0.000268409373738155 101 5 3 0.6 0.0297029702970297
KEGG KEGG:04621 NOD-like receptor signaling pathway 0.000868368257660462 177 11 4 0.363636363636364 0.0225988700564972
KEGG KEGG:03008 Ribosome biogenesis in eukaryotes 0.00911306717382291 99 34 4 0.117647058823529 0.0404040404040404
KEGG KEGG:05220 Chronic myeloid leukemia 0.0476678125162844 76 35 3 0.0857142857142857 0.0394736842105263
KEGG KEGG:05160 Hepatitis C 0.0477728658228675 157 35 4 0.114285714285714 0.0254777070063694
REAC REAC:R-HSA-380108 Chemokine receptors bind chemokines 1.92307809878016e-06 57 5 4 0.8 0.0701754385964912
REAC REAC:R-HSA-6783783 Interleukin-10 signaling 0.000121118850733568 45 5 3 0.6 0.0666666666666667
REAC REAC:R-HSA-375276 Peptide ligand-binding receptors 0.000121118850733568 195 5 4 0.8 0.0205128205128205
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.000139371181951334 446 15 7 0.466666666666667 0.015695067264574
REAC REAC:R-HSA-373076 Class A/1 (Rhodopsin-like receptors) 0.000451508739081634 328 5 4 0.8 0.0121951219512195
REAC REAC:R-HSA-418594 G alpha (i) signalling events 0.000829470830971183 401 5 4 0.8 0.00997506234413965
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 0.000829470830971183 842 16 8 0.5 0.00950118764845606
REAC REAC:R-HSA-500792 GPCR ligand binding 0.000997078616446848 459 5 4 0.8 0.00871459694989107
REAC REAC:R-HSA-72312 rRNA processing 0.000997078616446848 203 60 8 0.133333333333333 0.0394088669950739
REAC REAC:R-HSA-74259 Purine catabolism 0.00112198486691255 15 40 3 0.075 0.2
REAC REAC:R-HSA-5368286 Mitochondrial translation initiation 0.00158394932138349 87 111 7 0.0630630630630631 0.0804597701149425
REAC REAC:R-HSA-5368287 Mitochondrial translation 0.00223524075272814 93 111 7 0.0630630630630631 0.0752688172043011
REAC REAC:R-HSA-6790901 rRNA modification in the nucleus and cytosol 0.00258295203009649 60 123 6 0.0487804878048781 0.1
REAC REAC:R-HSA-5389840 Mitochondrial translation elongation 0.00278226725888845 87 88 6 0.0681818181818182 0.0689655172413793
REAC REAC:R-HSA-72766 Translation 0.00278226725888845 292 67 9 0.134328358208955 0.0308219178082192
REAC REAC:R-HSA-5419276 Mitochondrial translation termination 0.00278226725888845 87 88 6 0.0681818181818182 0.0689655172413793
REAC REAC:R-HSA-8868773 rRNA processing in the nucleus and cytosol 0.00310819694925566 193 60 7 0.116666666666667 0.0362694300518135
REAC REAC:R-HSA-8956319 Nucleobase catabolism 0.00649771440809188 32 40 3 0.075 0.09375
REAC REAC:R-HSA-8953854 Metabolism of RNA 0.00732782056771496 658 60 12 0.2 0.0182370820668693
REAC REAC:R-HSA-388396 GPCR downstream signalling 0.01240323458664 1088 5 4 0.8 0.00367647058823529
REAC REAC:R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 0.0132523623453429 183 60 6 0.1 0.0327868852459016
REAC REAC:R-HSA-372790 Signaling by GPCR 0.0144533415175589 1158 5 4 0.8 0.00345423143350604
REAC REAC:R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 0.0224663944392288 63 35 3 0.0857142857142857 0.0476190476190476
REAC REAC:R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 0.0312393661084726 113 51 4 0.0784313725490196 0.0353982300884956
REAC REAC:R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 0.0312393661084726 112 51 4 0.0784313725490196 0.0357142857142857
REAC REAC:R-HSA-5250924 B-WICH complex positively regulates rRNA expression 0.0312393661084726 54 109 4 0.036697247706422 0.0740740740740741
REAC REAC:R-HSA-72613 Eukaryotic Translation Initiation 0.0325542086589002 120 51 4 0.0784313725490196 0.0333333333333333
REAC REAC:R-HSA-72165 mRNA Splicing - Minor Pathway 0.0325542086589002 51 56 3 0.0535714285714286 0.0588235294117647
REAC REAC:R-HSA-72737 Cap-dependent Translation Initiation 0.0325542086589002 120 51 4 0.0784313725490196 0.0333333333333333
REAC REAC:R-HSA-168256 Immune System 0.0428733165030419 2139 24 11 0.458333333333333 0.00514258999532492
TF TF:M11425_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.000428033696782202 2330 76 27 0.355263157894737 0.011587982832618
TF TF:M09935 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN 0.000468330774740662 4420 122 51 0.418032786885246 0.0115384615384615
TF TF:M08759 Factor: c-Ets-2; motif: NCCGGAAGTG 0.000468330774740662 8319 135 84 0.622222222222222 0.0100973674720519
TF TF:M08913_1 Factor: FLI-1; motif: NAYTTCCGGT; match class: 1 0.000468330774740662 3055 110 37 0.336363636363636 0.0121112929623568
TF TF:M11399 Factor: Fli-1; motif: NACCGGAWWTCCGGTY 0.000468330774740662 12977 71 64 0.901408450704225 0.00493180241966556
TF TF:M08759_1 Factor: c-Ets-2; motif: NCCGGAAGTG; match class: 1 0.000468330774740662 2915 76 28 0.368421052631579 0.00960548885077187
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.000468330774740662 4963 113 52 0.460176991150442 0.0104775337497481
TF TF:M11404_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.000468330774740662 3171 69 28 0.405797101449275 0.00883002207505519
TF TF:M02073_1 Factor: Fli-1; motif: ACCGGAAGYN; match class: 1 0.000468330774740662 1488 69 19 0.27536231884058 0.0127688172043011
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.000468330774740662 4201 106 45 0.424528301886792 0.0107117353011188
TF TF:M11425 Factor: PEA3; motif: NACCGGAAGTN 0.000468330774740662 7428 137 79 0.576642335766423 0.0106354334948842
TF TF:M03989 Factor: FLI1; motif: ACCGGAAATCCGGT 0.000468330774740662 10442 130 95 0.730769230769231 0.00909787397050374
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.000468330774740662 4639 106 48 0.452830188679245 0.0103470575555077
TF TF:M00322 Factor: c-Myc:Max; motif: GCCAYGYGSN 0.000468330774740662 7873 110 71 0.645454545454546 0.00901816334307126
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.000468330774740662 10107 130 93 0.715384615384615 0.00920154348471357
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.000468330774740662 4056 132 51 0.386363636363636 0.0125739644970414
TF TF:M04714_1 Factor: Elf-1; motif: ACTTCCGGG; match class: 1 0.000468330774740662 2659 76 27 0.355263157894737 0.010154193305754
TF TF:M11498_1 Factor: OC-2; motif: NNATCGATYN; match class: 1 0.000468330774740662 396 11 5 0.454545454545455 0.0126262626262626
TF TF:M08377_1 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1 0.000468330774740662 5051 115 54 0.469565217391304 0.0106909522866759
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.000468330774740662 3759 105 41 0.39047619047619 0.0109071561585528
TF TF:M09904_1 Factor: Elk-1; motif: RCCGGAAGTGN; match class: 1 0.000468330774740662 2743 76 27 0.355263157894737 0.00984323733138899
TF TF:M09905_1 Factor: SAP-1; motif: NNCCGGAAGTGN; match class: 1 0.000468330774740662 2989 137 43 0.313868613138686 0.0143860823017732
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.000468330774740662 7045 132 75 0.568181818181818 0.0106458481192335
TF TF:M09913 Factor: ER81; motif: NNCCGGAAGYG 0.000468330774740662 2871 135 41 0.303703703703704 0.0142807384186695
TF TF:M01752_1 Factor: ERG; motif: ACCGGAART; match class: 1 0.000468330774740662 3705 69 30 0.434782608695652 0.00809716599190283
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.000468330774740662 8056 113 71 0.628318584070796 0.00881330685203575
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.000468330774740662 4024 106 43 0.405660377358491 0.0106858846918489
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.000468330774740662 6749 132 72 0.545454545454545 0.0106682471477256
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.000468330774740662 3233 110 39 0.354545454545455 0.0120630992885865
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0004783278922321 4902 122 54 0.442622950819672 0.011015911872705
TF TF:M02066_1 Factor: PEA3; motif: RCCGGAAGYN; match class: 1 0.000524133011100346 2283 76 24 0.315789473684211 0.0105124835742444
TF TF:M02055_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.000524133011100346 2176 69 22 0.318840579710145 0.0101102941176471
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.000524133011100346 10837 110 84 0.763636363636364 0.00775122266309864
TF TF:M01214_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.000524133011100346 2176 69 22 0.318840579710145 0.0101102941176471
TF TF:M04698 Factor: GABP-alpha; motif: CACTTCCGG 0.000552234277641454 3196 120 40 0.333333333333333 0.0125156445556946
TF TF:M03988_1 Factor: FLI1; motif: ACCGGAARTN; match class: 1 0.000558177123953209 2950 69 26 0.376811594202899 0.0088135593220339
TF TF:M02069_1 Factor: Erm; motif: ACCGGAAGTN; match class: 1 0.000567748201812206 1955 137 32 0.233576642335766 0.0163682864450128
TF TF:M01258 Factor: GABP; motif: CACTTCCGGNNN 0.000668122508830854 2838 135 40 0.296296296296296 0.0140944326990839
TF TF:M11424 Factor: Erm; motif: NNSCGGAWGYN 0.000672687123647501 8149 137 83 0.605839416058394 0.0101852988096699
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.000820566128693549 7544 132 76 0.575757575757576 0.0100742311770944
TF TF:M02071_1 Factor: ETV7; motif: NCCGGAANNN; match class: 1 0.000865105494962946 4465 110 46 0.418181818181818 0.0103023516237402
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.000947230557632948 4677 106 46 0.433962264150943 0.00983536454992517
TF TF:M11451_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.000968567405861733 2112 69 21 0.304347826086957 0.00994318181818182
TF TF:M03545_1 Factor: c-Rel; motif: NGGGAATYTCCN; match class: 1 0.000986595256315704 1011 11 6 0.545454545454545 0.00593471810089021
TF TF:M10094_1 Factor: RelA-p65; motif: NWGGGRATTTCCMN; match class: 1 0.000994736993407125 242 11 4 0.363636363636364 0.0165289256198347
TF TF:M11447 Factor: Elf-1; motif: NAMCCGGAAGTN 0.00108173268687996 7703 137 79 0.576642335766423 0.010255744515124
TF TF:M02053_1 Factor: ELF1; motif: NCCGGAARTN; match class: 1 0.00115782270559856 1559 122 25 0.204918032786885 0.0160359204618345
TF TF:M11427_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00115782270559856 4606 137 55 0.401459854014599 0.0119409465914025
TF TF:M09904 Factor: Elk-1; motif: RCCGGAAGTGN 0.00127482127309501 8164 135 81 0.6 0.00992160705536502
TF TF:M11401_1 Factor: Fli-1; motif: NACCGGATATCCGGTN; match class: 1 0.00157678852556501 11801 130 101 0.776923076923077 0.00855859672909075
TF TF:M11437 Factor: SAP-1; motif: NRCCGGAWGYN 0.00164358407393464 2788 69 24 0.347826086956522 0.00860832137733142
TF TF:M07415_1 Factor: Elf-1; motif: AWCCCGGAAGTN; match class: 1 0.00164358407393464 2397 69 22 0.318840579710145 0.00917813934084272
TF TF:M00774 Factor: NF-kappaB; motif: NGGGANTTYCCMNNNN 0.00164358407393464 1818 11 7 0.636363636363636 0.00385038503850385
TF TF:M01299 Factor: MECP2; motif: CCGGNNTTWA 0.00172839041522672 5228 11 10 0.909090909090909 0.00191277735271614
TF TF:M11420 Factor: ER81; motif: NACCGGAAGTN 0.00175915282363684 3210 69 26 0.376811594202899 0.00809968847352025
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.00182191261932322 10585 123 89 0.723577235772358 0.0084081247047709
TF TF:M03981 Factor: ETV3; motif: ACCGGAAGTN 0.00182191261932322 2327 103 28 0.271844660194175 0.0120326600773528
TF TF:M04706_1 Factor: RelA; motif: GGGRAWTYC; match class: 1 0.00182192008817544 344 32 6 0.1875 0.0174418604651163
TF TF:M00052 Factor: NF-kappaB; motif: GGGRATTTCC 0.00182192008817544 1874 11 7 0.636363636363636 0.00373532550693703
TF TF:M08222_1 Factor: Elk-1:HOXB13; motif: ACCGGAAGTNGTAAAN; match class: 1 0.00182192008817544 2063 69 20 0.289855072463768 0.00969461948618517
TF TF:M01165_1 Factor: Elk-1; motif: RACCGGAAGTR; match class: 1 0.00194752700650882 2185 110 28 0.254545454545455 0.0128146453089245
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.00194752700650882 8219 130 78 0.6 0.00949020562112179
TF TF:M11508_1 Factor: CDP; motif: NNATYGATYN; match class: 1 0.00198090664667768 1591 6 5 0.833333333333333 0.00314267756128221
TF TF:M02070_1 Factor: TEL1; motif: CNCGGAANNN; match class: 1 0.00204272379639555 4841 122 51 0.418032786885246 0.0105350134269779
TF TF:M03982 Factor: ETV4; motif: ACCGGAAGTN 0.00218860016239015 6826 132 69 0.522727272727273 0.0101084090243188
TF TF:M02073 Factor: Fli-1; motif: ACCGGAAGYN 0.00218860016239015 5839 76 40 0.526315789473684 0.00685048809727693
TF TF:M08223_1 Factor: Elk-1:OC-2; motif: RCCGGAASCGATCGATNN; match class: 1 0.00218860016239015 5853 71 38 0.535211267605634 0.00649239706133607
TF TF:M11413 Factor: ER71; motif: NACCGGAARTN 0.00223993736332097 2111 69 20 0.289855072463768 0.00947418285172904
TF TF:M11447_1 Factor: Elf-1; motif: NAMCCGGAAGTN; match class: 1 0.00231470565072489 2593 76 24 0.315789473684211 0.00925568839182414
TF TF:M11401 Factor: Fli-1; motif: NACCGGATATCCGGTN 0.00238963092149184 11952 130 101 0.776923076923077 0.00845046854082999
TF TF:M02056_1 Factor: ELF4; motif: NCCGGAARTN; match class: 1 0.00240509335508694 1291 68 15 0.220588235294118 0.0116189000774593
TF TF:M09901 Factor: nerf; motif: NNNCCGGAAGTGN 0.00240509335508694 5352 69 35 0.507246376811594 0.00653961136023916
TF TF:M11391_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.00243054840913156 9085 71 50 0.704225352112676 0.00550357732526142
TF TF:M11393_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.00243054840913156 13665 71 64 0.901408450704225 0.00468349798755946
TF TF:M04714 Factor: Elf-1; motif: ACTTCCGGG 0.00243054840913156 7798 137 78 0.569343065693431 0.0100025647601949
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.00243547663116646 14106 129 112 0.868217054263566 0.0079398837374167
TF TF:M02062_1 Factor: Erg; motif: ACCGGAAGTN; match class: 1 0.00245579456584405 2718 69 23 0.333333333333333 0.00846210448859456
TF TF:M11428_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0024813263105239 2146 69 20 0.289855072463768 0.00931966449207828
TF TF:M09605 Factor: Elf-1; motif: NAANCMGGAAGTGN 0.00251566580945843 5778 135 62 0.459259259259259 0.010730356524749
TF TF:M11421 Factor: ER81; motif: NACCGGAAGTN 0.00253868938687076 2341 69 21 0.304347826086957 0.00897052541648868
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.00260866497808652 4607 76 34 0.447368421052632 0.00738007380073801
TF TF:M11393 Factor: Erg; motif: NACCGGATATCCGGTN 0.00262831558389066 14105 71 65 0.915492957746479 0.00460829493087558
TF TF:M11424_1 Factor: Erm; motif: NNSCGGAWGYN; match class: 1 0.00269089220759731 2835 137 38 0.277372262773723 0.0134038800705467
TF TF:M00322_1 Factor: c-Myc:Max; motif: GCCAYGYGSN; match class: 1 0.00277937872667268 2862 98 30 0.306122448979592 0.010482180293501
TF TF:M03989_1 Factor: FLI1; motif: ACCGGAAATCCGGT; match class: 1 0.00277937872667268 5595 134 60 0.447761194029851 0.0107238605898123
TF TF:M11439 Factor: Net; motif: NRCCGGAAGTN 0.00291784269395841 2568 69 22 0.318840579710145 0.00856697819314642
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.00297949645131798 8322 113 69 0.610619469026549 0.00829127613554434
TF TF:M09935_1 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN; match class: 1 0.0030010018366542 1047 76 14 0.184210526315789 0.0133715377268386
TF TF:M11428 Factor: PEA3; motif: NACCGGAAGTN 0.0030010018366542 7186 137 73 0.532846715328467 0.0101586418035068
TF TF:M03983 Factor: ETV5; motif: NCCGGAWGYN 0.00302594560658864 3129 113 35 0.309734513274336 0.0111856823266219
TF TF:M10004 Factor: NF-kappaB2; motif: GGGRAANYCCC 0.00302594560658864 1073 5 4 0.8 0.00372786579683131
TF TF:M00194_1 Factor: NF-kappaB; motif: NGGGGAMTTTCCNN; match class: 1 0.00302594560658864 385 11 4 0.363636363636364 0.0103896103896104
TF TF:M02072 Factor: Pet-1; motif: ACCGGAWRTN 0.00302594560658864 2395 69 21 0.304347826086957 0.00876826722338205
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.00302594560658864 2702 71 23 0.323943661971831 0.00851221317542561
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.00302594560658864 5745 137 62 0.452554744525547 0.0107919930374238
TF TF:M02055 Factor: ESE-1; motif: NSMGGAARTN 0.00303846548218168 7559 71 44 0.619718309859155 0.00582087577721921
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.00303846548218168 11728 130 99 0.761538461538461 0.00844133697135061
TF TF:M01214 Factor: ESE-1; motif: NSMGGAARTN 0.00303846548218168 7559 71 44 0.619718309859155 0.00582087577721921
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 0.00307621896563742 14997 129 116 0.89922480620155 0.00773488030939521
TF TF:M11419 Factor: ER81; motif: NNCCGGAWGYN 0.00315715267244017 5699 122 56 0.459016393442623 0.00982628531321285
TF TF:M08472_1 Factor: Fli-1:E2A; motif: NCCGGAWRCASCTGN; match class: 1 0.00316593489766023 2240 8 6 0.75 0.00267857142857143
TF TF:M03970 Factor: ELK1; motif: ACCGGAAGTN 0.00317908577064135 4782 69 32 0.463768115942029 0.00669176076955249
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.00330266094804331 4592 122 48 0.39344262295082 0.0104529616724739
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.00339829846205141 14429 129 113 0.875968992248062 0.00783145055097373
TF TF:M02068 Factor: etv3; motif: ACCGGAAGYN 0.00362560095880251 3443 113 37 0.327433628318584 0.0107464420563462
TF TF:M00053_1 Factor: c-Rel; motif: SGGRNTTTCC; match class: 1 0.00374684065892107 426 11 4 0.363636363636364 0.00938967136150235
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.00374684065892107 9474 120 79 0.658333333333333 0.00833861093519105
TF TF:M04247 Factor: FOXJ2; motif: RTAAACAA 0.00374684065892107 1188 5 4 0.8 0.00336700336700337
TF TF:M07989 Factor: FOXG1; motif: RTAAACAW 0.00374684065892107 1188 5 4 0.8 0.00336700336700337
TF TF:M08205_1 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1 0.00374684065892107 10438 76 57 0.75 0.00546081624832343
TF TF:M11179 Factor: ASH-2; motif: ACACGACGCN 0.00381344510373507 2162 36 13 0.361111111111111 0.00601295097132285
TF TF:M02054 Factor: ELF2; motif: CCCGGAARYN 0.00382112847044938 3066 69 24 0.347826086956522 0.00782778864970646
TF TF:M11434_1 Factor: Elk-1; motif: NRSCGGAAGNN; match class: 1 0.00424710928643514 2935 137 38 0.277372262773723 0.0129471890971039
TF TF:M11430 Factor: PEA3; motif: NACCGGAAGTN 0.004742994248543 10865 130 93 0.715384615384615 0.00855959502991256
TF TF:M02067 Factor: ER71; motif: ACCGGAARYN 0.004742994248543 5930 71 37 0.52112676056338 0.00623946037099494
TF TF:M11414 Factor: GABP-alpha; motif: NACCGGAAGTN 0.00475967725884585 2907 69 23 0.333333333333333 0.00791193670450636
TF TF:M08231_1 Factor: Elk-1:T-bet; motif: TCACACCGGAAGNN; match class: 1 0.00476514607914397 1581 69 16 0.231884057971014 0.0101201771030993
TF TF:M03987 Factor: FEV; motif: ACCGGAAGTN 0.00476514607914397 1318 135 22 0.162962962962963 0.0166919575113809
TF TF:M07221 Factor: NF-kappaB1; motif: KGGRNTTTCCM 0.00476514607914397 2417 11 7 0.636363636363636 0.0028961522548614
TF TF:M02012 Factor: HIF-1alpha; motif: NCACGT 0.00476514607914397 6648 118 60 0.508474576271186 0.00902527075812274
TF TF:M01078_1 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN; match class: 1 0.00476514607914397 2448 135 33 0.244444444444444 0.0134803921568627
TF TF:M10094 Factor: RelA-p65; motif: NWGGGRATTTCCMN 0.00481210406328325 2429 11 7 0.636363636363636 0.00288184438040346
TF TF:M04743_1 Factor: c-Myc; motif: NSCACGTGGN; match class: 1 0.00484103585924542 3081 123 36 0.292682926829268 0.0116845180136319
TF TF:M00054 Factor: NF-kappaB; motif: GGGAMTTYCC 0.00484103585924542 2444 11 7 0.636363636363636 0.00286415711947627
TF TF:M02061 Factor: ERF; motif: ACCGGAARYN 0.00484103585924542 2579 113 30 0.265486725663717 0.0116324156649864
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.00484103585924542 13227 129 106 0.821705426356589 0.00801391093974446
TF TF:M11066_1 Factor: HES-7; motif: GNCACGYGNN; match class: 1 0.00484103585924542 8172 109 65 0.596330275229358 0.00795398923152227
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.00497122100804056 8273 106 64 0.60377358490566 0.00773600870300979
TF TF:M00799_1 Factor: Myc; motif: CACGTGS; match class: 1 0.00498230259606012 2722 123 33 0.268292682926829 0.0121234386480529
TF TF:M11487 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.00498230259606012 4329 71 30 0.422535211267606 0.00693000693000693
TF TF:M00032_1 Factor: c-Ets-1(p54); motif: NCMGGAWGYN; match class: 1 0.00510822855686078 2161 134 30 0.223880597014925 0.01388246182323
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.00510822855686078 9423 120 78 0.65 0.00827761859280484
TF TF:M02011 Factor: HES-1; motif: GSCACGMGMC 0.00521875670823325 4259 99 38 0.383838383838384 0.00892228222587462
TF TF:M09668 Factor: RelA-p65; motif: GGGRNTTTCCM 0.00546921662282747 3576 11 8 0.727272727272727 0.00223713646532438
TF TF:M09900 Factor: Elf-1; motif: NNANCCGGAAGTGS 0.00546921662282747 5219 69 33 0.478260869565217 0.00632305039279555
TF TF:M10438 Factor: ZF5; motif: GGSGCGCGS 0.00546921662282747 16228 129 121 0.937984496124031 0.0074562484594528
TF TF:M11391 Factor: Erg; motif: NACCGGATATCCGGTN 0.00552455249114052 10082 71 52 0.732394366197183 0.00515770680420551
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.0055460484403774 8318 77 49 0.636363636363636 0.00589083914402501
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.00562232771229928 8690 106 66 0.622641509433962 0.00759493670886076
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.00571412748683926 6033 71 37 0.52112676056338 0.00613293552129952
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.00571412748683926 11116 130 94 0.723076923076923 0.00845627923713566
TF TF:M11432_1 Factor: Elk-1; motif: NACMGGAAGTN; match class: 1 0.00571412748683926 1525 52 13 0.25 0.00852459016393443
TF TF:M11940_1 Factor: POU4F3; motif: TNATGCATNA; match class: 1 0.00571412748683926 644 9 4 0.444444444444444 0.0062111801242236
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.00574401316334123 5332 110 48 0.436363636363636 0.00900225056264066
TF TF:M03976 Factor: ERG; motif: ACCGGAWATCCGGT 0.00578762626915537 12803 137 109 0.795620437956204 0.00851362961805827
TF TF:M11451 Factor: Elf-1; motif: NANCCGGAAGTN 0.00578762626915537 6886 132 67 0.507575757575758 0.00972988672669184
TF TF:M01145 Factor: c-Myc; motif: RACCACGTGCTC 0.00583613946427209 6248 126 60 0.476190476190476 0.00960307298335467
TF TF:M11397 Factor: Erg; motif: NACCGGATATCCGGTN 0.00591646863585687 12005 71 58 0.816901408450704 0.00483132028321533
TF TF:M11442 Factor: Net; motif: NACCGGAAGTN 0.0059741091339939 2012 106 24 0.226415094339623 0.0119284294234592
TF TF:M00053 Factor: c-Rel; motif: SGGRNTTTCC 0.0059741091339939 3672 11 8 0.727272727272727 0.00217864923747277
TF TF:M02063_1 Factor: c-ets-1; motif: ACCGGAWGTN; match class: 1 0.0059741091339939 2396 135 32 0.237037037037037 0.013355592654424
TF TF:M03982_1 Factor: ETV4; motif: ACCGGAAGTN; match class: 1 0.0059741091339939 2009 69 18 0.260869565217391 0.00895968143354903
TF TF:M08760 Factor: ETV7; motif: NNSCGGAAGTR 0.00600985167449446 2349 103 26 0.252427184466019 0.011068539804172
TF TF:M07209 Factor: ELK4; motif: NCRCTTCCGGN 0.0060610978084051 1118 120 18 0.15 0.0161001788908766
TF TF:M11498 Factor: OC-2; motif: NNATCGATYN 0.00618183421853298 1129 6 4 0.666666666666667 0.00354295837023915
TF TF:M03990_1 Factor: GABPA; motif: ACCGGAAGTN; match class: 1 0.00634825185337191 1206 132 20 0.151515151515152 0.0165837479270315
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.00643600825919128 15268 130 117 0.9 0.00766308619334556
TF TF:M11397_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.00656278343446407 11731 71 57 0.802816901408451 0.00485892080811525
TF TF:M07612 Factor: PSF; motif: KWATCCGN 0.00666892824304076 5581 74 36 0.486486486486487 0.00645045690736427
TF TF:M08451_1 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA; match class: 1 0.00680767974904245 2584 70 21 0.3 0.00812693498452012
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.00705126976173337 10262 113 78 0.690265486725664 0.00760085753264471
TF TF:M07325_1 Factor: MaFA; motif: TCTGCTGASCNN; match class: 1 0.00717804621222421 522 5 3 0.6 0.00574712643678161
TF TF:M02054_1 Factor: ELF2; motif: CCCGGAARYN; match class: 1 0.00739577138956684 456 52 7 0.134615384615385 0.0153508771929825
TF TF:M04201_1 Factor: CEBPB; motif: ATTRCGCAAY; match class: 1 0.00742600643713478 1501 117 21 0.179487179487179 0.0139906728847435
TF TF:M05427 Factor: ZNF516; motif: YGTAAAGCCT 0.00754564068193959 550 73 9 0.123287671232877 0.0163636363636364
TF TF:M08910_1 Factor: C/EBPBETA; motif: KRTTGCGYAAY; match class: 1 0.00761509339928513 3194 123 36 0.292682926829268 0.0112711333750783
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.00805769500772336 5133 137 55 0.401459854014599 0.0107149814923047
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.00823802809444688 8743 77 50 0.649350649350649 0.00571886080292806
TF TF:M09772 Factor: GRHL2; motif: NNNAAACCAGTTNNN 0.00823802809444688 322 34 5 0.147058823529412 0.015527950310559
TF TF:M03972 Factor: ELK3; motif: ACCGGAAGTN 0.00839426018650281 1211 135 20 0.148148148148148 0.0165152766308836
TF TF:M11399_1 Factor: Fli-1; motif: NACCGGAWWTCCGGTY; match class: 1 0.00840602156907859 11513 71 56 0.788732394366197 0.00486406670720056
TF TF:M09607 Factor: SAP-1; motif: ACCGGAAGTNN 0.00872760430675047 4727 135 51 0.377777777777778 0.0107890839856146
TF TF:M09607_1 Factor: SAP-1; motif: ACCGGAAGTNN; match class: 1 0.00894508005291759 977 95 14 0.147368421052632 0.0143295803480041
TF TF:M11058_1 Factor: Hey1; motif: NGCRCGYGYN; match class: 1 0.00903876095551393 10925 74 56 0.756756756756757 0.00512585812356979
TF TF:M01154_1 Factor: c-Myc; motif: KACCACGTGSYY; match class: 1 0.00916229729829978 3751 73 27 0.36986301369863 0.0071980805118635
TF TF:M01243 Factor: MTF-1; motif: TGCGCAC 0.00942945967832869 2835 109 30 0.275229357798165 0.0105820105820106
TF TF:M09894 Factor: E2F-4; motif: SNGGGCGGGAANN 0.00955972460361961 16194 130 121 0.930769230769231 0.00747190317401507
TF TF:M11433_1 Factor: Elk-1; motif: NRCCGGAAGTN; match class: 1 0.00967048786879387 2261 135 30 0.222222222222222 0.0132684652808492
TF TF:M08526 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN 0.0100566588279595 16867 130 124 0.953846153846154 0.00735163336692951
TF TF:M08231 Factor: Elk-1:T-bet; motif: TCACACCGGAAGNN 0.0106077434048129 6635 137 66 0.481751824817518 0.00994724943481537
TF TF:M00104_1 Factor: CDP; motif: NATCGATCGS; match class: 1 0.0107220244895705 1353 6 4 0.666666666666667 0.00295639320029564
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.010915346091911 7600 113 62 0.548672566371681 0.00815789473684211
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.0112163545085453 10002 110 74 0.672727272727273 0.00739852029594081
TF TF:M09641 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN 0.0112979959499142 3222 134 38 0.283582089552239 0.0117939168218498
TF TF:M01240 Factor: BEN; motif: CAGCGRNV 0.0113735349393897 16498 132 124 0.939393939393939 0.00751606255303673
TF TF:M12171 Factor: LKLF; motif: NRCCMCRCCCN 0.0114792784535943 556 112 11 0.0982142857142857 0.0197841726618705
TF TF:M03545 Factor: c-Rel; motif: NGGGAATYTCCN 0.0115286328572043 5530 11 9 0.818181818181818 0.00162748643761302
TF TF:M01145_1 Factor: c-Myc; motif: RACCACGTGCTC; match class: 1 0.0115522346699516 3448 109 34 0.311926605504587 0.00986078886310905
TF TF:M11066 Factor: HES-7; motif: GNCACGYGNN 0.0117044786288609 11507 127 93 0.732283464566929 0.00808203702094377
TF TF:M11417 Factor: c-Ets-2; motif: NACCGGAAGYRCTTCCGGTN 0.0117775777508757 14334 70 63 0.9 0.00439514441188782
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.0117775777508757 10765 77 57 0.74025974025974 0.00529493729679517
TF TF:M04706 Factor: RelA; motif: GGGRAWTYC 0.0120159130555791 2278 7 5 0.714285714285714 0.00219490781387182
TF TF:M11436 Factor: SAP-1; motif: NRNCGGAWRYN 0.0126068852179837 1431 69 14 0.202898550724638 0.00978336827393431
TF TF:M11052_1 Factor: Hey2; motif: NNCACGYGNN; match class: 1 0.0126916807633448 9523 124 79 0.637096774193548 0.00829570513493647
TF TF:M08359_1 Factor: HOXD12:Elk-1; motif: NRNCGGAAGTCGTAAAN; match class: 1 0.012708703705885 1166 114 17 0.149122807017544 0.0145797598627787
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.0127269500596507 10253 130 87 0.669230769230769 0.00848532136935531
TF TF:M11438 Factor: SAP-1; motif: NTCGTAAATGCN 0.0127269500596507 5901 73 36 0.493150684931507 0.00610066090493137
TF TF:M03970_1 Factor: ELK1; motif: ACCGGAAGTN; match class: 1 0.0127269500596507 1097 69 12 0.173913043478261 0.0109389243391067
TF TF:M03557_1 Factor: P50; motif: GGRRANTCCCNN; match class: 1 0.0130669027123261 1292 11 5 0.454545454545455 0.00386996904024768
TF TF:M09608_1 Factor: Erg; motif: NNACCGGAARTSN; match class: 1 0.0133228166517655 2389 69 19 0.27536231884058 0.00795311845960653
TF TF:M11446 Factor: Elf-1; motif: RANSMGGAAGTR 0.0138709508275699 2915 124 33 0.266129032258065 0.0113207547169811
TF TF:M07464_1 Factor: Prep-1; motif: GRBTGANAGATN; match class: 1 0.0142863794734724 607 90 10 0.111111111111111 0.0164744645799012
TF TF:M00054_1 Factor: NF-kappaB; motif: GGGAMTTYCC; match class: 1 0.0142863794734724 712 5 3 0.6 0.00421348314606742
TF TF:M11417_1 Factor: c-Ets-2; motif: NACCGGAAGYRCTTCCGGTN; match class: 1 0.0142863794734724 14041 70 62 0.885714285714286 0.0044156399116872
TF TF:M10003 Factor: NF-kappaB1; motif: AGGGAAAK 0.0150062715323846 1983 5 4 0.8 0.00201714573877963
TF TF:M11415 Factor: GABP-alpha; motif: NRCCGGAAGTN 0.0150140650662276 3257 69 23 0.333333333333333 0.00706171323303654
TF TF:M03976_1 Factor: ERG; motif: ACCGGAWATCCGGT; match class: 1 0.0154592197903287 7781 125 68 0.544 0.00873923660197918
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.0154592197903287 11053 129 91 0.705426356589147 0.00823305889803673
TF TF:M11603 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0156633699630569 16361 76 73 0.960526315789474 0.0044618299614938
TF TF:M11767 Factor: TR4; motif: NRGGTCAN 0.0156633699630569 454 100 9 0.09 0.0198237885462555
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.0156730116631303 6892 106 54 0.509433962264151 0.00783517121300058
TF TF:M09814_1 Factor: MYCN; motif: NNCCACGTGGNN; match class: 1 0.0158232207576082 2066 45 13 0.288888888888889 0.00629235237173282
TF TF:M09814 Factor: MYCN; motif: NNCCACGTGGNN 0.0158232207576082 2066 45 13 0.288888888888889 0.00629235237173282
TF TF:M04926_1 Factor: REST; motif: AAGGTGCT; match class: 1 0.0160307015955878 1189 25 7 0.28 0.00588730025231287
TF TF:M00716 Factor: ZF5; motif: GSGCGCGR 0.016074970516869 16103 129 119 0.922480620155039 0.00738992734273117
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 0.016074970516869 14575 125 108 0.864 0.00740994854202401
TF TF:M04059 Factor: NRF-1; motif: YGCGCATGCGCN 0.0160823210005644 1471 111 19 0.171171171171171 0.0129163834126445
TF TF:M11081_1 Factor: SREBP-1; motif: RTCRCGTGAY; match class: 1 0.0165836267901499 7890 74 44 0.594594594594595 0.0055766793409379
TF TF:M04259 Factor: FOXO3; motif: GTAAACAW 0.01690157874947 2079 5 4 0.8 0.00192400192400192
TF TF:M09606 Factor: nerf; motif: NRRNSCGGAAGNRNNNN 0.0173353501493553 6249 137 62 0.452554744525547 0.00992158745399264
TF TF:M11316_1 Factor: C/EBPbeta; motif: NRTTGCGYAAYN; match class: 1 0.0176787593784424 2743 123 31 0.252032520325203 0.011301494713817
TF TF:M04926 Factor: REST; motif: AAGGTGCT 0.0177935887873975 6325 44 25 0.568181818181818 0.00395256916996047
TF TF:M11940 Factor: POU4F3; motif: TNATGCATNA 0.0180244405184641 975 9 4 0.444444444444444 0.0041025641025641
TF TF:M08917_1 Factor: GABP-ALPHA; motif: RCCGGAARTNN; match class: 1 0.018314352615018 389 120 9 0.075 0.0231362467866324
TF TF:M00122 Factor: USF; motif: NNRNCACGTGNYNN 0.018314352615018 2413 60 17 0.283333333333333 0.00704517198508081
TF TF:M00122_1 Factor: USF; motif: NNRNCACGTGNYNN; match class: 1 0.018314352615018 2413 60 17 0.283333333333333 0.00704517198508081
TF TF:M11432 Factor: Elk-1; motif: NACMGGAAGTN 0.0187202428108923 6140 137 61 0.445255474452555 0.00993485342019544
TF TF:M07380 Factor: E2F-4; motif: NTTTCSCGCC 0.0191448694522379 13022 130 103 0.792307692307692 0.00790969129166027
TF TF:M09606_1 Factor: nerf; motif: NRRNSCGGAAGNRNNNN; match class: 1 0.0194614823030867 1704 69 15 0.217391304347826 0.00880281690140845
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.019519727006396 11275 123 88 0.715447154471545 0.00780487804878049
TF TF:M00106_1 Factor: CDP; motif: NATYGATSSS; match class: 1 0.0197013267467371 1686 6 4 0.666666666666667 0.00237247924080664
TF TF:M11486_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.0203829371360641 2952 136 35 0.257352941176471 0.0118563685636856
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.0212454363186446 10116 106 71 0.669811320754717 0.00701858442071965
TF TF:M01692 Factor: LTF; motif: GKVACTTNC 0.0213136123747191 4173 47 20 0.425531914893617 0.00479271507308891
TF TF:M00032 Factor: c-Ets-1(p54); motif: NCMGGAWGYN 0.0217138988068585 7858 69 41 0.594202898550725 0.00521761262407737
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.0217519311773843 11232 130 92 0.707692307692308 0.00819088319088319
TF TF:M11454 Factor: ELFR; motif: NANGMGGAAGTN 0.0217519311773843 1072 120 16 0.133333333333333 0.0149253731343284
TF TF:M11052 Factor: Hey2; motif: NNCACGYGNN 0.0217519311773843 12502 129 99 0.767441860465116 0.00791873300271956
TF TF:M11054 Factor: Hey2; motif: NGCACGYGYN 0.0217519311773843 3318 109 32 0.293577981651376 0.00964436407474382
TF TF:M08345_1 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN; match class: 1 0.0217582255616641 2198 109 24 0.220183486238532 0.010919017288444
TF TF:M02102 Factor: NRF-1; motif: YGCGCMTGCGC 0.0218356955410863 2020 125 25 0.2 0.0123762376237624
TF TF:M11433 Factor: Elk-1; motif: NRCCGGAAGTN 0.0219377011159034 7679 137 72 0.525547445255474 0.00937622086209142
TF TF:M03563_1 Factor: RelA-p65; motif: GGGANTTTCCNN; match class: 1 0.0220513991746108 876 5 3 0.6 0.00342465753424658
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.022487354436622 14873 114 100 0.87719298245614 0.00672359308814631
TF TF:M00474 Factor: FOXO1; motif: GNNTTGTTTACNTT 0.0227351302679854 2777 13 7 0.538461538461538 0.00252070579762333
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.0227351302679854 12747 137 106 0.773722627737226 0.00831568212128344
TF TF:M09805 Factor: FOXK1; motif: NNNGTAAACANGNN 0.0227351302679854 890 5 3 0.6 0.00337078651685393
TF TF:M11395 Factor: Erg; motif: NACCGGAWWTCCGGTN 0.0227351302679854 8715 113 67 0.592920353982301 0.00768789443488239
TF TF:M01224 Factor: P50:RELA-P65; motif: GGANTTYCCCWN 0.0231595379623436 2329 5 4 0.8 0.0017174753112924
TF TF:M11414_1 Factor: GABP-alpha; motif: NACCGGAAGTN; match class: 1 0.0231710144389745 442 69 7 0.101449275362319 0.0158371040723982
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.023363019931145 14473 129 110 0.852713178294574 0.00760035928971188
TF TF:M00224 Factor: STAT1; motif: NNNSANTTCCGGGAANTGNSN 0.0234046800308857 5609 8 7 0.875 0.00124799429488322
TF TF:M11508 Factor: CDP; motif: NNATYGATYN 0.0234046800308857 3768 13 8 0.615384615384615 0.00212314225053079
TF TF:M04743 Factor: c-Myc; motif: NSCACGTGGN 0.0234502342751114 4819 123 46 0.373983739837398 0.00954554886905997
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.0235558720915894 15072 130 114 0.876923076923077 0.00756369426751592
TF TF:M01163_1 Factor: Elk-1; motif: AACCGGAAGTR; match class: 1 0.0236288539896844 1086 47 9 0.191489361702128 0.00828729281767956
TF TF:M09611 Factor: ER81; motif: NNNGRCMGGAAGYRNNNNNNNS 0.0236288539896844 2666 135 32 0.237037037037037 0.0120030007501875
TF TF:M10018_1 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS; match class: 1 0.0252504186451102 851 111 13 0.117117117117117 0.0152761457109283
TF TF:M08341_1 Factor: HOXB2:Elk-1; motif: TAATKRCCGGAAGTN; match class: 1 0.0253849444741846 1317 120 18 0.15 0.0136674259681093
TF TF:M04515_1 Factor: E2F-1; motif: WWTGGCGCCAAA; match class: 1 0.0253849444741846 12173 76 60 0.789473684210526 0.00492894109915386
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 0.0253849444741846 16263 130 120 0.923076923076923 0.00737871241468364
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.0255129998499013 12550 132 101 0.765151515151515 0.00804780876494024
TF TF:M00799 Factor: Myc; motif: CACGTGS 0.0257174157646113 4988 123 47 0.382113821138211 0.00942261427425822
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.02572735256012 7600 137 71 0.518248175182482 0.00934210526315789
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.0262386317951831 10430 65 47 0.723076923076923 0.00450623202301055
TF TF:M09755 Factor: ZNF295; motif: NYCYCWGCYYCCCN 0.0264839439742859 3281 135 37 0.274074074074074 0.0112770496799756
TF TF:M01177 Factor: SREBP-2; motif: NNGYCACNNSMN 0.0266736109369137 8829 40 28 0.7 0.00317136708574017
TF TF:M09932 Factor: FOXO3a; motif: NYTGTTTACN 0.0266736109369137 2895 13 7 0.538461538461538 0.00241796200345423
TF TF:M11382 Factor: ESE-1; motif: NWTRCGGAWGCN 0.0266736109369137 10339 137 90 0.656934306569343 0.00870490376245285
TF TF:M06632 Factor: ZNF717; motif: GGGAAAAAGA 0.0266736109369137 259 16 3 0.1875 0.0115830115830116
TF TF:M09982 Factor: c-MAF; motif: NNAWNTGCTGASNNNGCNN 0.0270809726067356 1959 83 18 0.216867469879518 0.00918836140888208
TF TF:M00123 Factor: c-Myc:Max; motif: NANCACGTGNNW 0.0270809726067356 3337 63 21 0.333333333333333 0.00629307761462391
TF TF:M09992 Factor: c-Myc; motif: NCCACGTGCNN 0.0273856923000086 5627 45 23 0.511111111111111 0.00408743557846099
TF TF:M04694 Factor: NRF-1; motif: CNCTGCGCATGCGC 0.0273881085749597 1548 121 20 0.165289256198347 0.0129198966408269
TF TF:M01231 Factor: ZNF515; motif: GTGGGGGGTM 0.0278433245000753 1424 86 15 0.174418604651163 0.0105337078651685
TF TF:M11053 Factor: Hey2; motif: NGCACGTGYN 0.0282812961728104 1262 87 14 0.160919540229885 0.0110935023771791
TF TF:M11450 Factor: Elf-1; motif: NANSCGGAAGTR 0.0284120261921693 5601 120 50 0.416666666666667 0.00892697732547759
TF TF:M04323_1 Factor: GBX2; motif: TAATTGNNCAATTA; match class: 1 0.0284120261921693 69 60 3 0.05 0.0434782608695652
TF TF:M04202_1 Factor: CEBPD; motif: RTTRCGCAAY; match class: 1 0.0287602876173725 1980 117 23 0.196581196581197 0.0116161616161616
TF TF:M08208_1 Factor: E2F-3:FOXI1; motif: NGACACCGCGCCCAC; match class: 1 0.0290122902140883 7127 113 57 0.504424778761062 0.00799775501613582
TF TF:M00088_1 Factor: Ik-3; motif: TNYTGGGAATACC; match class: 1 0.0292771761920747 1019 5 3 0.6 0.00294406280667321
TF TF:M11061 Factor: HES-1; motif: GGCRCGTGNC 0.0303529141120161 6271 127 57 0.448818897637795 0.00908945941636103
TF TF:M11422 Factor: Erm; motif: NRCMGGAAGTN 0.0304070226861413 4669 69 28 0.405797101449275 0.00599700149925037
TF TF:M12187_1 Factor: KLF17; motif: NMCCACNCWCCCNTN; match class: 1 0.030557417844108 377 12 3 0.25 0.00795755968169761
TF TF:M00473 Factor: FOXO1; motif: NRWAAACAAN 0.0308071944007893 2604 5 4 0.8 0.00153609831029186
TF TF:M00477 Factor: FOXO3; motif: TNNTTGTTTACNTW 0.0310689244310706 2612 5 4 0.8 0.00153139356814701
TF TF:M07384 Factor: HIF-1alpha; motif: NCACGTNN 0.0311886774985251 1206 45 9 0.2 0.00746268656716418
TF TF:M11215 Factor: N-Myc; motif: NNCACGTGNN 0.0311886774985251 1206 45 9 0.2 0.00746268656716418
TF TF:M04263 Factor: FOXO4; motif: TTTCCCCACACG 0.0314194081928883 383 43 5 0.116279069767442 0.0130548302872063
TF TF:M03791 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY 0.0314194081928883 2969 135 34 0.251851851851852 0.0114516672280229
TF TF:M02074_1 Factor: GABPalpha; motif: RCCGGAWRYN; match class: 1 0.0315672552283379 1005 135 16 0.118518518518519 0.0159203980099502
TF TF:M03990 Factor: GABPA; motif: ACCGGAAGTN 0.03191966917857 5258 71 31 0.436619718309859 0.00589577786230506
TF TF:M00208 Factor: NF-kappaB; motif: NGGGACTTTCCA 0.0319217434037787 3757 11 7 0.636363636363636 0.00186318871439979
TF TF:M07415 Factor: Elf-1; motif: AWCCCGGAAGTN 0.0321399167583453 7978 107 59 0.551401869158878 0.0073953371772374
TF TF:M10018 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS 0.0321399167583453 1816 121 22 0.181818181818182 0.0121145374449339
TF TF:M11934 Factor: Oct3; motif: WTATGCGCATAW 0.0321399167583453 9694 126 79 0.626984126984127 0.00814937074479059
TF TF:M03812 Factor: arnt; motif: CACGYA 0.0324900094566519 4330 135 45 0.333333333333333 0.0103926096997691
TF TF:M02100 Factor: MyoD; motif: CASCTGNCN 0.0327053895829369 616 8 3 0.375 0.00487012987012987
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.0328623583551235 10512 106 72 0.679245283018868 0.00684931506849315
TF TF:M04018 Factor: IRF7; motif: NCGAAARYGAAANT 0.0329496005349419 619 8 3 0.375 0.00484652665589661
TF TF:M12230 Factor: LRF; motif: RCGACCACCNN 0.0331802594975851 8543 11 10 0.909090909090909 0.00117054898747513
TF TF:M11400 Factor: Fli-1; motif: NACCGGAARTN 0.0336122307273493 9946 106 69 0.650943396226415 0.00693746229640056
TF TF:M09784_1 Factor: RELB; motif: NNATTCCCCNN; match class: 1 0.0336122307273493 931 70 10 0.142857142857143 0.0107411385606874
TF TF:M04498_1 Factor: VDR; motif: GRGTTCATYGRGTTCA; match class: 1 0.0336122307273493 876 6 3 0.5 0.00342465753424658
TF TF:M00797_1 Factor: HIF1; motif: GNNKACGTGCGGNN; match class: 1 0.0336122307273493 549 137 11 0.0802919708029197 0.0200364298724954
TF TF:M11057 Factor: Hey1; motif: NGCACGTGYN 0.0340822861814811 1107 80 12 0.15 0.010840108401084
TF TF:M05889 Factor: ZNF676; motif: KGKGCAGGCTKH 0.0340822861814811 296 16 3 0.1875 0.0101351351351351
TF TF:M05522 Factor: ZNF341; motif: NTGGGGGGGGGG 0.0340822861814811 82 121 4 0.0330578512396694 0.0487804878048781
TF TF:M01208 Factor: FLI-1; motif: CMGGAWGTSAN 0.0340822861814811 6232 69 34 0.492753623188406 0.00545571245186136
TF TF:M00476 Factor: FOXO4; motif: NNGTTGTTTACNTN 0.0344381838178063 2740 5 4 0.8 0.00145985401459854
TF TF:M08868 Factor: ARNTLIKE; motif: NNNSCACGTG 0.0344489049774356 5094 123 47 0.382113821138211 0.00922654102866117
TF TF:M11420_1 Factor: ER81; motif: NACCGGAAGTN; match class: 1 0.0345717595968727 494 69 7 0.101449275362319 0.01417004048583
TF TF:M04710_1 Factor: CHD2; motif: TCTCGCGAG; match class: 1 0.0345717595968727 11477 76 57 0.75 0.00496645464842729
TF TF:M07291_1 Factor: GLI2; motif: TGGGTGGTCNS; match class: 1 0.0350756976998828 282 120 7 0.0583333333333333 0.024822695035461
TF TF:M11068 Factor: HES-5; motif: GGCACGTGYC 0.0350756976998828 313 80 6 0.075 0.0191693290734824
TF TF:M09641_1 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN; match class: 1 0.0353513036579844 991 114 14 0.12280701754386 0.0141271442986882
TF TF:M08313_1 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR; match class: 1 0.0355812712798175 9721 137 85 0.62043795620438 0.00874395638308816
TF TF:M01298 Factor: MECP2; motif: CCGGSNNNANNAWWT 0.0357371384582496 1290 9 4 0.444444444444444 0.00310077519379845
TF TF:M08359 Factor: HOXD12:Elk-1; motif: NRNCGGAAGTCGTAAAN 0.0360243337201252 6152 65 32 0.492307692307692 0.00520156046814044
TF TF:M00290 Factor: Freac-2; motif: NNANNGTAAACAANNN 0.0361223088247131 2798 5 4 0.8 0.00142959256611866
TF TF:M11415_1 Factor: GABP-alpha; motif: NRCCGGAAGTN; match class: 1 0.0361223088247131 546 47 6 0.127659574468085 0.010989010989011
TF TF:M08451 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA 0.0361918640156595 8421 71 43 0.605633802816901 0.00510628191426196
TF TF:M07084_1 Factor: E2F-4; motif: NGGCGGGAARN; match class: 1 0.0362149025635812 5437 15 10 0.666666666666667 0.00183924958616884
TF TF:M08445_1 Factor: AP-4:Fli-1; motif: RSCGGAWRCAGSTGN; match class: 1 0.0363285453044579 3143 13 7 0.538461538461538 0.0022271714922049
TF TF:M06293 Factor: ZNF742; motif: NGGGACGAGGSC 0.0363285453044579 234 108 6 0.0555555555555556 0.0256410256410256
TF TF:M11582 Factor: FOXI1; motif: AAYRTAAACAAT 0.0363285453044579 1155 5 3 0.6 0.0025974025974026
TF TF:M09901_1 Factor: nerf; motif: NNNCCGGAAGTGN; match class: 1 0.0364628855087516 1363 58 11 0.189655172413793 0.00807043286867205
TF TF:M00262 Factor: Staf; motif: NTTWCCCANMATGCAYYRCGNY 0.0364628855087516 1301 28 7 0.25 0.005380476556495
TF TF:M06444 Factor: ZNF557; motif: NCCGCKTCCTGC 0.0364628855087516 1344 134 19 0.141791044776119 0.0141369047619048
TF TF:M11570 Factor: HNF-3alpha; motif: CNYTAAGTAAACAAAN 0.0364966464103433 3651 88 28 0.318181818181818 0.00766913174472747
TF TF:M11601 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0368767076944553 14823 57 52 0.912280701754386 0.00350806179585779
TF TF:M01261 Factor: HNF3A; motif: RWGTAAACAN 0.0368767076944553 2840 5 4 0.8 0.00140845070422535
TF TF:M08637 Factor: TEF-3:Erg; motif: ACCGGAAATRNNNNNCATWCC 0.0368767076944553 4382 124 42 0.338709677419355 0.00958466453674121
TF TF:M02090 Factor: E2F-4; motif: GCGGGAAANA 0.0368907051868134 11966 109 81 0.743119266055046 0.00676917934146749
TF TF:M11047 Factor: CLOCK; motif: NMCACGTGYN 0.0369732376438874 479 54 6 0.111111111111111 0.0125260960334029
TF TF:M07048 Factor: MafG; motif: CMATGACTCAGCAGA 0.0375130432447961 6972 6 6 1 0.000860585197934596
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.0375606728504651 12401 129 97 0.751937984496124 0.00782194984275462
TF TF:M04059_1 Factor: NRF-1; motif: YGCGCATGCGCN; match class: 1 0.0376673522048246 1033 111 14 0.126126126126126 0.0135527589545015
TF TF:M00341 Factor: GABP; motif: VCCGGAAGNGCR 0.0381647602666568 8224 53 33 0.622641509433962 0.00401264591439689
TF TF:M01239 Factor: RelB:p52; motif: GGGGNTTTCC 0.0384921245083305 796 7 3 0.428571428571429 0.00376884422110553
TF TF:M04519 Factor: E2F-4; motif: TTTGGCGCCAAA 0.0384921245083305 4861 41 19 0.463414634146341 0.00390866076938901
TF TF:M00678 Factor: Tel-2; motif: YTACTTCCTG 0.0390663886774316 5292 69 30 0.434782608695652 0.00566893424036281
TF TF:M10815 Factor: HOXC11; motif: NRTCGTAAANN 0.0395010314267887 1139 41 8 0.195121951219512 0.00702370500438982
TF TF:M00055 Factor: N-Myc; motif: NNCCACGTGNNN 0.0395744801809643 4167 123 40 0.32520325203252 0.00959923206143509
TF TF:M03924_1 Factor: YY1; motif: NNCGCCATTNN; match class: 1 0.0395744801809643 3700 129 38 0.294573643410853 0.0102702702702703
TF TF:M11877_1 Factor: pax-2; motif: NCGTCACGCNYSRNYGCNYN; match class: 1 0.0400046419811569 5304 129 50 0.387596899224806 0.00942684766214178
TF TF:M08207 Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT 0.0414704799664937 17055 130 123 0.946153846153846 0.00721196130167106
TF TF:M03830_1 Factor: MafB; motif: CRCTGACNANN; match class: 1 0.0414925739170952 1592 24 7 0.291666666666667 0.00439698492462312
TF TF:M11018_1 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN; match class: 1 0.0414925739170952 15920 74 69 0.932432432432432 0.00433417085427136
TF TF:M08222 Factor: Elk-1:HOXB13; motif: ACCGGAAGTNGTAAAN 0.041569413264779 7653 137 70 0.510948905109489 0.00914673984058539
TF TF:M11452 Factor: Elf-1; motif: NANGCGGAAGTR 0.0416312302474744 6276 132 58 0.439393939393939 0.00924155513065647
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.041943545592095 14593 70 62 0.885714285714286 0.00424861234838621
TF TF:M01154 Factor: c-Myc; motif: KACCACGTGSYY 0.041943545592095 5313 123 48 0.390243902439024 0.00903444381705251
TF TF:M03973 Factor: ELK4; motif: ACCGGAARTN 0.0420992581071934 700 130 12 0.0923076923076923 0.0171428571428571
TF TF:M08525 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM 0.0425440729108018 17065 130 123 0.946153846153846 0.00720773513038383
TF TF:M08339_1 Factor: HOXB2:Elf-1; motif: SCGGAAGTMRTTA; match class: 1 0.0425712230907499 94 117 4 0.0341880341880342 0.0425531914893617
TF TF:M08418_1 Factor: TEF-3:Elk-1; motif: RMATWCCGGAWGT; match class: 1 0.0425712230907499 5247 73 31 0.424657534246575 0.00590813798360968
TF TF:M11098_1 Factor: Max; motif: NCACGTGNNNNNCACGTGN; match class: 1 0.0425712230907499 628 58 7 0.120689655172414 0.0111464968152866
TF TF:M08539 Factor: ERF:HOXA3; motif: ACCGGAARYNNNNNNMATTA 0.0425712230907499 167 66 4 0.0606060606060606 0.0239520958083832
TF TF:M09613_1 Factor: Fli-1; motif: RCMGGAAGYGNNN; match class: 1 0.0425712230907499 866 120 13 0.108333333333333 0.0150115473441109
TF TF:M11457 Factor: nerf; motif: NANGCGGAAGTR 0.0425712230907499 1082 120 15 0.125 0.0138632162661738
TF TF:M04015 Factor: IRF-4; motif: NCGAAACCGAAACYA 0.0427345458977191 2038 47 12 0.25531914893617 0.00588812561334642
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.043064364552324 10939 123 84 0.682926829268293 0.00767894688728403
TF TF:M11382_1 Factor: ESE-1; motif: NWTRCGGAWGCN; match class: 1 0.043064364552324 4112 137 43 0.313868613138686 0.0104571984435798
TF TF:M08952_1 Factor: NF-KAPPAB1; motif: NGGKRNTTYCCCN; match class: 1 0.044180640752061 3457 7 5 0.714285714285714 0.00144634075788256
TF TF:M11486 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.044180640752061 3658 136 39 0.286764705882353 0.0106615636960087
TF TF:M01759 Factor: AML2; motif: AACCRCAA 0.044180640752061 3027 33 12 0.363636363636364 0.00396432111000991
TF TF:M10083 Factor: STAT6; motif: TTCTSWGGAAN 0.044180640752061 3065 5 4 0.8 0.00130505709624796
TF TF:M04516_1 Factor: E2F-1; motif: TTTGGCGCCAAA; match class: 1 0.044180640752061 10227 13 12 0.923076923076923 0.00117336462305661
TF TF:M11387 Factor: elf5; motif: NNNNMGGAAGTN 0.044180640752061 2598 135 30 0.222222222222222 0.0115473441108545
TF TF:M08457_1 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY; match class: 1 0.044180640752061 5591 115 47 0.408695652173913 0.00840636737614022
TF TF:M08232_1 Factor: Elk-1:TEF; motif: RCCGGAAGTTACGTAAN; match class: 1 0.044180640752061 1294 5 3 0.6 0.00231839258114374
TF TF:M11580 Factor: FOXI1; motif: NWANNGTAAACAA 0.0445810930939441 1302 5 3 0.6 0.00230414746543779
TF TF:M11452_1 Factor: Elf-1; motif: NANGCGGAAGTR; match class: 1 0.0447875213479328 1696 135 22 0.162962962962963 0.0129716981132075
TF TF:M00704 Factor: TEF-1; motif: GRRATG 0.0447875213479328 12334 74 58 0.783783783783784 0.00470244851629642
TF TF:M11098 Factor: Max; motif: NCACGTGNNNNNCACGTGN 0.0466678720028628 826 58 8 0.137931034482759 0.00968523002421308
TF TF:M11075 Factor: Sohlh2; motif: NNCACGTGNN 0.0473630697432657 11927 63 49 0.777777777777778 0.00410832564769011
TF TF:M11533_1 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN; match class: 1 0.0474443512839641 8705 111 64 0.576576576576577 0.00735209649626651
TF TF:M11606 Factor: LEF-1; motif: ASATCAAAG 0.0476258772962242 6098 5 5 1 0.000819940964250574
TF TF:M01163 Factor: Elk-1; motif: AACCGGAAGTR 0.0489236906697907 5260 113 44 0.389380530973451 0.00836501901140684
TF TF:M03832 Factor: Net; motif: CACTTCCKGK 0.0489236906697907 929 76 10 0.131578947368421 0.0107642626480086
TF TF:M03925 Factor: YY2; motif: NCCGCCATNTY 0.0495809924476741 4641 127 44 0.346456692913386 0.0094807153630683
WP WP:WP5039 SARS-CoV-2 Innate Immunity Evasion and Cell-specific immune response 0.0016630488981509 68 5 3 0.6 0.0441176470588235
WP WP:WP4754 IL-18 signaling pathway 0.0110383135783286 279 24 6 0.25 0.021505376344086
WP WP:WP2431 Spinal Cord Injury 0.0140747055279424 118 9 3 0.333333333333333 0.0254237288135593
WP WP:WP4659 Gastrin Signaling Pathway 0.0392325722271395 114 16 3 0.1875 0.0263157894736842
WP WP:WP3646 Hepatitis C and Hepatocellular Carcinoma 0.0392325722271395 50 35 3 0.0857142857142857 0.06

pEpi06 transcription factor target enrichment of top program genes

TF enrichment of pEpi06
Possible regulators of activation of pEpi06 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.