pM02 program activity among Myeloid cells

Activation of pM02
pM02 gene program activation in Myeloid cells.
Gene program activation of pM02 by different cell subtypes
pM02 gene program activation among cells of different subtypes (Myeloid cells).

pM02 top program genes

Top genes of pM02 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pM02 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pM02
pM02 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0042221 response to chemical 7.68653997065373e-09 4781 88 54 0.613636363636364 0.0112947082200376
GO:BP GO:0001775 cell activation 7.68653997065373e-09 1495 88 30 0.340909090909091 0.020066889632107
GO:BP GO:0010033 response to organic substance 7.68653997065373e-09 3412 93 47 0.505376344086022 0.0137749120750293
GO:BP GO:0040011 locomotion 9.36520920782928e-09 2028 86 34 0.395348837209302 0.0167652859960552
GO:BP GO:0045229 external encapsulating structure organization 9.5240876929005e-09 404 92 17 0.184782608695652 0.0420792079207921
GO:BP GO:0043062 extracellular structure organization 9.5240876929005e-09 402 92 17 0.184782608695652 0.0422885572139304
GO:BP GO:0030198 extracellular matrix organization 9.5240876929005e-09 401 92 17 0.184782608695652 0.0423940149625935
GO:BP GO:0034097 response to cytokine 1.32219322177822e-08 1226 91 27 0.296703296703297 0.0220228384991843
GO:BP GO:0045321 leukocyte activation 3.26586857151242e-08 1332 88 27 0.306818181818182 0.0202702702702703
GO:BP GO:0002376 immune system process 8.85764769358012e-08 3278 92 43 0.467391304347826 0.013117754728493
GO:BP GO:0022617 extracellular matrix disassembly 8.85764769358012e-08 82 90 9 0.1 0.109756097560976
GO:BP GO:0071345 cellular response to cytokine stimulus 1.15115558374922e-07 1132 87 24 0.275862068965517 0.0212014134275618
GO:BP GO:0016477 cell migration 1.16092109287614e-07 1649 83 28 0.337349397590361 0.0169799878714372
GO:BP GO:0006955 immune response 1.30439759101222e-07 2311 91 35 0.384615384615385 0.0151449588922544
GO:BP GO:0051674 localization of cell 2.01978850483439e-07 1828 83 29 0.349397590361446 0.0158643326039387
GO:BP GO:0048870 cell motility 2.01978850483439e-07 1828 83 29 0.349397590361446 0.0158643326039387
GO:BP GO:0002366 leukocyte activation involved in immune response 2.60970455371685e-07 717 88 19 0.215909090909091 0.0264993026499303
GO:BP GO:0002263 cell activation involved in immune response 2.70249069995675e-07 721 88 19 0.215909090909091 0.0263522884882108
GO:BP GO:0002252 immune effector process 3.26064663629858e-07 1309 88 25 0.284090909090909 0.0190985485103132
GO:BP GO:0019221 cytokine-mediated signaling pathway 3.73086418265235e-07 810 81 19 0.234567901234568 0.0234567901234568
GO:BP GO:0030334 regulation of cell migration 3.87164389168874e-07 999 82 21 0.25609756097561 0.021021021021021
GO:BP GO:0070887 cellular response to chemical stimulus 4.24496982434123e-07 3393 82 39 0.475609756097561 0.0114942528735632
GO:BP GO:0002274 myeloid leukocyte activation 4.24496982434123e-07 667 88 18 0.204545454545455 0.0269865067466267
GO:BP GO:0030574 collagen catabolic process 4.79971297942678e-07 47 90 7 0.0777777777777778 0.148936170212766
GO:BP GO:0002443 leukocyte mediated immunity 7.95913056863735e-07 877 88 20 0.227272727272727 0.0228050171037628
GO:BP GO:0040012 regulation of locomotion 8.44278554369125e-07 1104 86 22 0.255813953488372 0.0199275362318841
GO:BP GO:2000145 regulation of cell motility 8.44554247373841e-07 1061 82 21 0.25609756097561 0.0197926484448633
GO:BP GO:0032879 regulation of localization 8.44554247373841e-07 2872 82 35 0.426829268292683 0.0121866295264624
GO:BP GO:0046686 response to cadmium ion 8.64979987548076e-07 65 41 6 0.146341463414634 0.0923076923076923
GO:BP GO:0006928 movement of cell or subcellular component 1.34136021143687e-06 2311 83 31 0.373493975903614 0.0134141064474254
GO:BP GO:0071276 cellular response to cadmium ion 2.24684723766524e-06 37 41 5 0.121951219512195 0.135135135135135
GO:BP GO:0051270 regulation of cellular component movement 2.63069163473583e-06 1141 82 21 0.25609756097561 0.0184049079754601
GO:BP GO:0009888 tissue development 3.70296454049214e-06 2107 66 25 0.378787878787879 0.0118652112007594
GO:BP GO:0051179 localization 4.17864382688423e-06 6901 94 62 0.659574468085106 0.00898420518765396
GO:BP GO:0002275 myeloid cell activation involved in immune response 5.67114830381407e-06 547 88 15 0.170454545454545 0.0274223034734918
GO:BP GO:0002444 myeloid leukocyte mediated immunity 6.06473559203928e-06 551 88 15 0.170454545454545 0.0272232304900181
GO:BP GO:0050776 regulation of immune response 7.0112433520717e-06 996 82 19 0.231707317073171 0.0190763052208835
GO:BP GO:0065008 regulation of biological quality 7.62048930722138e-06 4131 94 45 0.478723404255319 0.0108932461873638
GO:BP GO:0032963 collagen metabolic process 8.84440521791876e-06 114 90 8 0.0888888888888889 0.0701754385964912
GO:BP GO:0071800 podosome assembly 8.84440521791876e-06 17 129 5 0.0387596899224806 0.294117647058824
GO:BP GO:1901700 response to oxygen-containing compound 8.84440521791876e-06 1739 93 27 0.290322580645161 0.0155261644623347
GO:BP GO:0042119 neutrophil activation 9.41875260176496e-06 498 88 14 0.159090909090909 0.0281124497991968
GO:BP GO:0002446 neutrophil mediated immunity 9.41875260176496e-06 497 88 14 0.159090909090909 0.028169014084507
GO:BP GO:0032502 developmental process 9.41875260176496e-06 6628 130 77 0.592307692307692 0.0116173808086904
GO:BP GO:0007166 cell surface receptor signaling pathway 9.41875260176496e-06 3210 82 35 0.426829268292683 0.0109034267912773
GO:BP GO:0048856 anatomical structure development 9.41875260176496e-06 6106 130 73 0.561538461538462 0.0119554536521454
GO:BP GO:0007155 cell adhesion 1.00006679644161e-05 1492 43 16 0.372093023255814 0.0107238605898123
GO:BP GO:0022610 biological adhesion 1.023375515443e-05 1499 43 16 0.372093023255814 0.0106737825216811
GO:BP GO:0036230 granulocyte activation 1.023375515443e-05 504 88 14 0.159090909090909 0.0277777777777778
GO:BP GO:0010038 response to metal ion 1.08206559174109e-05 371 55 10 0.181818181818182 0.0269541778975741
GO:BP GO:0071310 cellular response to organic substance 1.12269194191219e-05 2776 82 32 0.390243902439024 0.0115273775216138
GO:BP GO:0035295 tube development 1.38026040658761e-05 1146 84 20 0.238095238095238 0.0174520069808028
GO:BP GO:0043299 leukocyte degranulation 1.8960741246475e-05 535 88 14 0.159090909090909 0.0261682242990654
GO:BP GO:0006887 exocytosis 1.8960741246475e-05 904 88 18 0.204545454545455 0.0199115044247788
GO:BP GO:0014070 response to organic cyclic compound 2.47090599159842e-05 967 93 19 0.204301075268817 0.0196483971044467
GO:BP GO:0010243 response to organonitrogen compound 2.62467830822518e-05 1085 84 19 0.226190476190476 0.0175115207373272
GO:BP GO:0050896 response to stimulus 3.42262747163085e-05 9407 89 69 0.775280898876405 0.00733496332518337
GO:BP GO:0043312 neutrophil degranulation 3.49743583913583e-05 482 88 13 0.147727272727273 0.0269709543568465
GO:BP GO:0002283 neutrophil activation involved in immune response 3.68730178057003e-05 485 88 13 0.147727272727273 0.0268041237113402
GO:BP GO:0030036 actin cytoskeleton organization 3.94032026554647e-05 709 129 19 0.147286821705426 0.0267983074753173
GO:BP GO:0050801 ion homeostasis 3.94861971741879e-05 808 93 17 0.182795698924731 0.021039603960396
GO:BP GO:0030155 regulation of cell adhesion 4.18110671010419e-05 748 42 11 0.261904761904762 0.0147058823529412
GO:BP GO:0048878 chemical homeostasis 4.18110671010419e-05 1229 100 22 0.22 0.0179007323026851
GO:BP GO:0048585 negative regulation of response to stimulus 4.18110671010419e-05 1733 47 17 0.361702127659574 0.00980957876514714
GO:BP GO:0046916 cellular transition metal ion homeostasis 4.29568780864732e-05 116 50 6 0.12 0.0517241379310345
GO:BP GO:0022411 cellular component disassembly 4.50011137627814e-05 571 90 14 0.155555555555556 0.0245183887915937
GO:BP GO:0010632 regulation of epithelial cell migration 4.92590270932046e-05 306 46 8 0.173913043478261 0.0261437908496732
GO:BP GO:0045055 regulated exocytosis 5.47910404683271e-05 785 88 16 0.181818181818182 0.0203821656050955
GO:BP GO:0030324 lung development 5.47910404683271e-05 173 20 5 0.25 0.0289017341040462
GO:BP GO:0030029 actin filament-based process 5.73842836865861e-05 808 129 20 0.155038759689922 0.0247524752475248
GO:BP GO:0030323 respiratory tube development 5.92990032974444e-05 177 20 5 0.25 0.0282485875706215
GO:BP GO:0051128 regulation of cellular component organization 5.92990032974444e-05 2412 129 38 0.294573643410853 0.0157545605306799
GO:BP GO:0030335 positive regulation of cell migration 6.15675820139868e-05 567 46 10 0.217391304347826 0.017636684303351
GO:BP GO:1901698 response to nitrogen compound 6.37134476536901e-05 1172 84 19 0.226190476190476 0.0162116040955631
GO:BP GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 6.61947443836969e-05 18 86 4 0.0465116279069767 0.222222222222222
GO:BP GO:0035239 tube morphogenesis 6.61947443836969e-05 950 84 17 0.202380952380952 0.0178947368421053
GO:BP GO:0071801 regulation of podosome assembly 7.92232141459448e-05 13 129 4 0.0310077519379845 0.307692307692308
GO:BP GO:0071248 cellular response to metal ion 8.26572430626476e-05 192 55 7 0.127272727272727 0.0364583333333333
GO:BP GO:2000147 positive regulation of cell motility 8.26572430626476e-05 591 46 10 0.217391304347826 0.0169204737732657
GO:BP GO:0030003 cellular cation homeostasis 9.41793636734718e-05 673 51 11 0.215686274509804 0.0163447251114413
GO:BP GO:0055076 transition metal ion homeostasis 9.41793636734718e-05 138 50 6 0.12 0.0434782608695652
GO:BP GO:0060541 respiratory system development 9.41793636734718e-05 199 20 5 0.25 0.0251256281407035
GO:BP GO:0051272 positive regulation of cellular component movement 9.56364138928731e-05 604 46 10 0.217391304347826 0.0165562913907285
GO:BP GO:0040017 positive regulation of locomotion 9.73381988860337e-05 606 46 10 0.217391304347826 0.0165016501650165
GO:BP GO:0006873 cellular ion homeostasis 0.000110373860296958 687 51 11 0.215686274509804 0.0160116448326055
GO:BP GO:0051716 cellular response to stimulus 0.000112478345011999 7781 89 60 0.674157303370786 0.00771109111939339
GO:BP GO:0055082 cellular chemical homeostasis 0.000115818792541442 841 51 12 0.235294117647059 0.014268727705113
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.000117389118165014 263 129 11 0.0852713178294574 0.0418250950570342
GO:BP GO:0042592 homeostatic process 0.000117389118165014 1981 55 19 0.345454545454545 0.00959111559818274
GO:BP GO:0009725 response to hormone 0.000117389118165014 921 91 17 0.186813186813187 0.0184581976112921
GO:BP GO:0050900 leukocyte migration 0.000138982115332669 511 83 12 0.144578313253012 0.0234833659491194
GO:BP GO:0001667 ameboidal-type cell migration 0.000138982115332669 494 46 9 0.195652173913043 0.0182186234817814
GO:BP GO:0010631 epithelial cell migration 0.000146076546395355 370 46 8 0.173913043478261 0.0216216216216216
GO:BP GO:0090132 epithelium migration 0.000153393203457515 373 46 8 0.173913043478261 0.0214477211796247
GO:BP GO:0009653 anatomical structure morphogenesis 0.00016076930708605 2797 127 40 0.31496062992126 0.0143010368251698
GO:BP GO:0007275 multicellular organism development 0.000165441476454114 5613 135 67 0.496296296296296 0.0119365758061643
GO:BP GO:0071241 cellular response to inorganic substance 0.000165441476454114 220 55 7 0.127272727272727 0.0318181818181818
GO:BP GO:0090130 tissue migration 0.000165487404739935 379 46 8 0.173913043478261 0.0211081794195251
GO:BP GO:0048514 blood vessel morphogenesis 0.000166209723957923 711 84 14 0.166666666666667 0.019690576652602
GO:BP GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 0.000170941573608058 24 86 4 0.0465116279069767 0.166666666666667
GO:BP GO:0001525 angiogenesis 0.000179580089094074 617 84 13 0.154761904761905 0.0210696920583468
GO:BP GO:0048731 system development 0.000184005853740747 5052 84 43 0.511904761904762 0.00851148060174188
GO:BP GO:0019725 cellular homeostasis 0.000195596062066752 981 55 13 0.236363636363636 0.0132517838939857
GO:BP GO:0001944 vasculature development 0.000196161123835627 830 84 15 0.178571428571429 0.0180722891566265
GO:BP GO:0030154 cell differentiation 0.000202504110073276 4350 84 39 0.464285714285714 0.00896551724137931
GO:BP GO:0055080 cation homeostasis 0.000205219484547482 750 51 11 0.215686274509804 0.0146666666666667
GO:BP GO:0010648 negative regulation of cell communication 0.000207458746185502 1468 82 20 0.24390243902439 0.0136239782016349
GO:BP GO:0034341 response to interferon-gamma 0.000207458746185502 196 91 8 0.0879120879120879 0.0408163265306122
GO:BP GO:0050793 regulation of developmental process 0.000207458746185502 2605 128 38 0.296875 0.0145873320537428
GO:BP GO:0032940 secretion by cell 0.000207458746185502 1364 88 20 0.227272727272727 0.0146627565982405
GO:BP GO:0048519 negative regulation of biological process 0.000207458746185502 5757 47 30 0.638297872340426 0.00521104742053153
GO:BP GO:0023057 negative regulation of signaling 0.000207458746185502 1471 82 20 0.24390243902439 0.0135961930659415
GO:BP GO:0070372 regulation of ERK1 and ERK2 cascade 0.000207458746185502 309 77 9 0.116883116883117 0.029126213592233
GO:BP GO:0048513 animal organ development 0.000207458746185502 3672 52 25 0.480769230769231 0.0068082788671024
GO:BP GO:0042493 response to drug 0.000208465468949919 396 132 13 0.0984848484848485 0.0328282828282828
GO:BP GO:0048584 positive regulation of response to stimulus 0.000212365607033202 2344 91 28 0.307692307692308 0.0119453924914676
GO:BP GO:0098771 inorganic ion homeostasis 0.000213511133010447 761 51 11 0.215686274509804 0.0144546649145861
GO:BP GO:0009967 positive regulation of signal transduction 0.000219236365985217 1598 47 15 0.319148936170213 0.00938673341677096
GO:BP GO:0002682 regulation of immune system process 0.000219305439690011 1617 82 21 0.25609756097561 0.012987012987013
GO:BP GO:0050865 regulation of cell activation 0.000219305439690011 655 82 13 0.158536585365854 0.0198473282442748
GO:BP GO:0046903 secretion 0.000225734969056852 1501 88 21 0.238636363636364 0.0139906728847435
GO:BP GO:0000165 MAPK cascade 0.000229514270750585 935 77 15 0.194805194805195 0.0160427807486631
GO:BP GO:0010035 response to inorganic substance 0.000230160522892964 575 55 10 0.181818181818182 0.0173913043478261
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 0.000231428705824315 1202 84 18 0.214285714285714 0.0149750415973378
GO:BP GO:0043068 positive regulation of programmed cell death 0.000262497208408621 621 88 13 0.147727272727273 0.0209339774557166
GO:BP GO:0048869 cellular developmental process 0.000263177707865928 4428 84 39 0.464285714285714 0.00880758807588076
GO:BP GO:0070371 ERK1 and ERK2 cascade 0.000290663709012452 329 118 11 0.0932203389830508 0.033434650455927
GO:BP GO:0050777 negative regulation of immune response 0.000295069207140174 157 34 5 0.147058823529412 0.0318471337579618
GO:BP GO:0022604 regulation of cell morphogenesis 0.000297947699577336 309 126 11 0.0873015873015873 0.0355987055016181
GO:BP GO:0043408 regulation of MAPK cascade 0.000314183682110975 730 77 13 0.168831168831169 0.0178082191780822
GO:BP GO:0140352 export from cell 0.000318907757867628 1418 88 20 0.227272727272727 0.0141043723554302
GO:BP GO:0006810 transport 0.000325226175374497 5224 94 47 0.5 0.00899693721286371
GO:BP GO:0048518 positive regulation of biological process 0.000326442214359576 6363 95 54 0.568421052631579 0.00848656294200849
GO:BP GO:0008360 regulation of cell shape 0.000330970057309079 154 126 8 0.0634920634920635 0.051948051948052
GO:BP GO:0009719 response to endogenous stimulus 0.000347809233215471 1683 114 26 0.228070175438596 0.0154486036838978
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.000358615878505457 540 136 15 0.110294117647059 0.0277777777777778
GO:BP GO:0040013 negative regulation of locomotion 0.000388326608001905 401 51 8 0.156862745098039 0.0199501246882793
GO:BP GO:0035556 intracellular signal transduction 0.000388326608001905 2772 77 27 0.350649350649351 0.00974025974025974
GO:BP GO:0048583 regulation of response to stimulus 0.000388326608001905 4278 91 40 0.43956043956044 0.00935016362786349
GO:BP GO:0045446 endothelial cell differentiation 0.000391220509246058 125 77 6 0.0779220779220779 0.048
GO:BP GO:0044087 regulation of cellular component biogenesis 0.000391220509246058 990 136 21 0.154411764705882 0.0212121212121212
GO:BP GO:0001568 blood vessel development 0.000391229293270897 792 84 14 0.166666666666667 0.0176767676767677
GO:BP GO:0006950 response to stress 0.000392178117246817 4170 87 38 0.436781609195402 0.00911270983213429
GO:BP GO:0060429 epithelium development 0.000399628879487838 1325 66 16 0.242424242424242 0.0120754716981132
GO:BP GO:0048523 negative regulation of cellular process 0.000400204741067852 5139 58 32 0.551724137931034 0.00622689239151586
GO:BP GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 0.000400204741067852 108 26 4 0.153846153846154 0.037037037037037
GO:BP GO:0010647 positive regulation of cell communication 0.000400204741067852 1777 91 23 0.252747252747253 0.0129431626336522
GO:BP GO:0002003 angiotensin maturation 0.000400204741067852 12 78 3 0.0384615384615385 0.25
GO:BP GO:0002002 regulation of angiotensin levels in blood 0.000400204741067852 12 78 3 0.0384615384615385 0.25
GO:BP GO:0002685 regulation of leukocyte migration 0.000409830873413155 211 70 7 0.1 0.033175355450237
GO:BP GO:0023056 positive regulation of signaling 0.000409830873413155 1782 91 23 0.252747252747253 0.0129068462401796
GO:BP GO:0002694 regulation of leukocyte activation 0.000438033150385392 610 82 12 0.146341463414634 0.019672131147541
GO:BP GO:0035987 endodermal cell differentiation 0.000438094068837721 45 21 3 0.142857142857143 0.0666666666666667
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.000445969890267015 236 26 5 0.192307692307692 0.0211864406779661
GO:BP GO:0002684 positive regulation of immune system process 0.000450889896397266 1065 82 16 0.195121951219512 0.0150234741784038
GO:BP GO:0090066 regulation of anatomical structure size 0.000488899449678481 518 82 11 0.134146341463415 0.0212355212355212
GO:BP GO:0006979 response to oxidative stress 0.000555792287890332 466 127 13 0.102362204724409 0.0278969957081545
GO:BP GO:0007159 leukocyte cell-cell adhesion 0.000557365683043726 375 135 12 0.0888888888888889 0.032
GO:BP GO:0002697 regulation of immune effector process 0.000559601773598783 461 77 10 0.12987012987013 0.0216919739696312
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.000560494653528908 460 129 13 0.10077519379845 0.0282608695652174
GO:BP GO:0010942 positive regulation of cell death 0.000560494653528908 684 88 13 0.147727272727273 0.0190058479532164
GO:BP GO:1901888 regulation of cell junction assembly 0.000581971543227553 202 78 7 0.0897435897435897 0.0346534653465347
GO:BP GO:0051234 establishment of localization 0.000583349921948694 5372 94 47 0.5 0.00874906924795235
GO:BP GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.000590402236794754 41 26 3 0.115384615384615 0.0731707317073171
GO:BP GO:0016192 vesicle-mediated transport 0.000590402236794754 2180 88 25 0.284090909090909 0.0114678899082569
GO:BP GO:0045785 positive regulation of cell adhesion 0.000593958280888629 437 82 10 0.121951219512195 0.022883295194508
GO:BP GO:0072359 circulatory system development 0.000608783944619019 1194 84 17 0.202380952380952 0.0142378559463987
GO:BP GO:0009966 regulation of signal transduction 0.000608783944619019 3165 6 6 1 0.0018957345971564
GO:BP GO:0043066 negative regulation of apoptotic process 0.000636492688139945 921 26 8 0.307692307692308 0.00868621064060804
GO:BP GO:0071222 cellular response to lipopolysaccharide 0.000637737972578594 200 110 8 0.0727272727272727 0.04
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.00064137550165208 2541 110 32 0.290909090909091 0.0125934671389217
GO:BP GO:0051239 regulation of multicellular organismal process 0.00064137550165208 2861 46 19 0.41304347826087 0.00664103460328556
GO:BP GO:0071346 cellular response to interferon-gamma 0.00064137550165208 175 38 5 0.131578947368421 0.0285714285714286
GO:BP GO:0001990 regulation of systemic arterial blood pressure by hormone 0.00064137550165208 38 86 4 0.0465116279069767 0.105263157894737
GO:BP GO:0001706 endoderm formation 0.00066182142620559 54 21 3 0.142857142857143 0.0555555555555556
GO:BP GO:0003158 endothelium development 0.000668598905552232 143 77 6 0.0779220779220779 0.041958041958042
GO:BP GO:0008283 cell population proliferation 0.000679923790181319 2054 83 23 0.27710843373494 0.0111976630963973
GO:BP GO:0010594 regulation of endothelial cell migration 0.000679923790181319 244 46 6 0.130434782608696 0.0245901639344262
GO:BP GO:0043065 positive regulation of apoptotic process 0.000693994396553878 604 88 12 0.136363636363636 0.0198675496688742
GO:BP GO:0008284 positive regulation of cell population proliferation 0.000702265392329202 982 83 15 0.180722891566265 0.0152749490835031
GO:BP GO:0043069 negative regulation of programmed cell death 0.000704559089413985 943 26 8 0.307692307692308 0.00848356309650053
GO:BP GO:0007584 response to nutrient 0.000726683520424649 182 91 7 0.0769230769230769 0.0384615384615385
GO:BP GO:0031532 actin cytoskeleton reorganization 0.000730009551788565 106 106 6 0.0566037735849057 0.0566037735849057
GO:BP GO:0050790 regulation of catalytic activity 0.000758382027818395 2545 111 32 0.288288288288288 0.012573673870334
GO:BP GO:0006879 cellular iron ion homeostasis 0.000759936725478197 69 50 4 0.08 0.0579710144927536
GO:BP GO:0032496 response to lipopolysaccharide 0.000782364227688601 338 110 10 0.0909090909090909 0.029585798816568
GO:BP GO:0071803 positive regulation of podosome assembly 0.000789108188275578 10 129 3 0.0232558139534884 0.3
GO:BP GO:0042981 regulation of apoptotic process 0.000795915123103572 1549 88 20 0.227272727272727 0.012911555842479
GO:BP GO:0051246 regulation of protein metabolic process 0.000800705318470455 2704 110 33 0.3 0.0122041420118343
GO:BP GO:0030855 epithelial cell differentiation 0.000802333077228466 798 91 14 0.153846153846154 0.0175438596491228
GO:BP GO:0022409 positive regulation of cell-cell adhesion 0.000817302615202604 284 82 8 0.0975609756097561 0.028169014084507
GO:BP GO:0048522 positive regulation of cellular process 0.000877613892004117 5757 95 49 0.515789473684211 0.00851137745353483
GO:BP GO:0071219 cellular response to molecule of bacterial origin 0.000909674002747216 214 110 8 0.0727272727272727 0.0373831775700935
GO:BP GO:0051130 positive regulation of cellular component organization 0.000940918077086577 1153 82 16 0.195121951219512 0.0138768430182134
GO:BP GO:0032535 regulation of cellular component size 0.000946111715881677 388 46 7 0.152173913043478 0.0180412371134021
GO:BP GO:0007165 signal transduction 0.000987135428004426 6309 95 52 0.547368421052632 0.00824219369155175
GO:BP GO:0006915 apoptotic process 0.00101372584339639 1990 88 23 0.261363636363636 0.0115577889447236
GO:BP GO:0043067 regulation of programmed cell death 0.00101372584339639 1582 88 20 0.227272727272727 0.0126422250316056
GO:BP GO:0010646 regulation of cell communication 0.00101372584339639 3543 6 6 1 0.00169348010160881
GO:BP GO:0002521 leukocyte differentiation 0.00104876773092787 550 134 14 0.104477611940299 0.0254545454545455
GO:BP GO:0023051 regulation of signaling 0.00106370821716951 3578 6 6 1 0.00167691447736165
GO:BP GO:0010634 positive regulation of epithelial cell migration 0.00106370821716951 181 42 5 0.119047619047619 0.0276243093922652
GO:BP GO:0046649 lymphocyte activation 0.00107872042921444 771 135 17 0.125925925925926 0.0220492866407263
GO:BP GO:0051641 cellular localization 0.00110781649955151 3541 70 28 0.4 0.00790737079920926
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.00112683737929485 1477 125 24 0.192 0.016249153689912
GO:BP GO:0002520 immune system development 0.00117417266897364 1020 135 20 0.148148148148148 0.0196078431372549
GO:BP GO:0060548 negative regulation of cell death 0.00120461980744866 1038 26 8 0.307692307692308 0.00770712909441233
GO:BP GO:0002237 response to molecule of bacterial origin 0.00120461980744866 361 110 10 0.0909090909090909 0.0277008310249307
GO:BP GO:0040007 growth 0.00122390762092835 967 110 17 0.154545454545455 0.0175801447776629
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 0.00125466284250139 159 26 4 0.153846153846154 0.0251572327044025
GO:BP GO:0046683 response to organophosphorus 0.00126592457511987 137 93 6 0.0645161290322581 0.0437956204379562
GO:BP GO:0042110 T cell activation 0.00127446757760428 489 135 13 0.0962962962962963 0.0265848670756646
GO:BP GO:0009743 response to carbohydrate 0.00130296209425862 243 77 7 0.0909090909090909 0.0288065843621399
GO:BP GO:0034599 cellular response to oxidative stress 0.00130296209425862 316 127 10 0.078740157480315 0.0316455696202532
GO:BP GO:0060323 head morphogenesis 0.00130296209425862 36 42 3 0.0714285714285714 0.0833333333333333
GO:BP GO:0006882 cellular zinc ion homeostasis 0.00131042022110239 37 41 3 0.0731707317073171 0.0810810810810811
GO:BP GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.00133142536367018 59 26 3 0.115384615384615 0.0508474576271186
GO:BP GO:1905521 regulation of macrophage migration 0.00138418581778422 42 37 3 0.0810810810810811 0.0714285714285714
GO:BP GO:0006508 proteolysis 0.00138418581778422 1836 110 25 0.227272727272727 0.0136165577342048
GO:BP GO:0043542 endothelial cell migration 0.00140857866795366 290 46 6 0.130434782608696 0.0206896551724138
GO:BP GO:0009968 negative regulation of signal transduction 0.00140857866795366 1364 45 12 0.266666666666667 0.00879765395894428
GO:BP GO:0051591 response to cAMP 0.00140857866795366 97 84 5 0.0595238095238095 0.0515463917525773
GO:BP GO:0006954 inflammatory response 0.00143638418039966 794 86 13 0.151162790697674 0.0163727959697733
GO:BP GO:0023052 signaling 0.0014516196209257 6810 82 48 0.585365853658537 0.00704845814977974
GO:BP GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 0.0014516196209257 50 86 4 0.0465116279069767 0.08
GO:BP GO:0035690 cellular response to drug 0.0014516196209257 70 118 5 0.0423728813559322 0.0714285714285714
GO:BP GO:0055072 iron ion homeostasis 0.0014516196209257 86 50 4 0.08 0.0465116279069767
GO:BP GO:0055069 zinc ion homeostasis 0.0014516196209257 39 41 3 0.0731707317073171 0.0769230769230769
GO:BP GO:0045765 regulation of angiogenesis 0.00146836860531877 358 73 8 0.10958904109589 0.0223463687150838
GO:BP GO:0007154 cell communication 0.0015412606165018 6829 82 48 0.585365853658537 0.0070288475618685
GO:BP GO:0048534 hematopoietic or lymphoid organ development 0.0015412606165018 966 135 19 0.140740740740741 0.0196687370600414
GO:BP GO:0006952 defense response 0.00155256719636584 1818 4 4 1 0.0022002200220022
GO:BP GO:0071216 cellular response to biotic stimulus 0.00156173389077378 238 110 8 0.0727272727272727 0.0336134453781513
GO:BP GO:0051129 negative regulation of cellular component organization 0.0015713264212824 759 46 9 0.195652173913043 0.0118577075098814
GO:BP GO:0007492 endoderm development 0.00157261380880191 80 21 3 0.142857142857143 0.0375
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.00158086808243673 1042 126 19 0.150793650793651 0.0182341650671785
GO:BP GO:1901342 regulation of vasculature development 0.00158667248661611 364 73 8 0.10958904109589 0.021978021978022
GO:BP GO:0051336 regulation of hydrolase activity 0.0015874756446831 1321 126 22 0.174603174603175 0.0166540499621499
GO:BP GO:1903306 negative regulation of regulated secretory pathway 0.0015874756446831 22 77 3 0.038961038961039 0.136363636363636
GO:BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 0.00162129357764339 241 82 7 0.0853658536585366 0.029045643153527
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.00166323600290571 1227 91 17 0.186813186813187 0.0138549307253464
GO:BP GO:0042127 regulation of cell population proliferation 0.00166323600290571 1774 83 20 0.240963855421687 0.0112739571589628
GO:BP GO:0001885 endothelial cell development 0.00166323600290571 69 125 5 0.04 0.072463768115942
GO:BP GO:0031099 regeneration 0.00166348153262263 206 129 8 0.062015503875969 0.0388349514563107
GO:BP GO:0098609 cell-cell adhesion 0.00166841442378037 894 135 18 0.133333333333333 0.0201342281879195
GO:BP GO:0046688 response to copper ion 0.00167139238872969 42 41 3 0.0731707317073171 0.0714285714285714
GO:BP GO:0050922 negative regulation of chemotaxis 0.00175449232303951 65 71 4 0.0563380281690141 0.0615384615384615
GO:BP GO:0001952 regulation of cell-matrix adhesion 0.00177700548830318 127 110 6 0.0545454545454545 0.047244094488189
GO:BP GO:0030834 regulation of actin filament depolymerization 0.00182453103857297 57 82 4 0.0487804878048781 0.0701754385964912
GO:BP GO:0065009 regulation of molecular function 0.00186535134877697 3221 111 36 0.324324324324324 0.0111766532132878
GO:BP GO:0014074 response to purine-containing compound 0.00186535134877697 152 93 6 0.0645161290322581 0.0394736842105263
GO:BP GO:0001960 negative regulation of cytokine-mediated signaling pathway 0.00192303615648152 82 58 4 0.0689655172413793 0.0487804878048781
GO:BP GO:0051093 negative regulation of developmental process 0.00192303615648152 977 46 10 0.217391304347826 0.0102354145342886
GO:BP GO:2001233 regulation of apoptotic signaling pathway 0.00199634112914792 363 26 5 0.192307692307692 0.0137741046831956
GO:BP GO:1903037 regulation of leukocyte cell-cell adhesion 0.00199634112914792 338 82 8 0.0975609756097561 0.0236686390532544
GO:BP GO:1903959 regulation of anion transmembrane transport 0.00199634112914792 115 79 5 0.0632911392405063 0.0434782608695652
GO:BP GO:0051247 positive regulation of protein metabolic process 0.00200127287304426 1564 95 20 0.210526315789474 0.0127877237851662
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.00200710000525527 1037 89 15 0.168539325842697 0.0144648023143684
GO:BP GO:1901564 organonitrogen compound metabolic process 0.00200743982824859 6792 107 59 0.551401869158878 0.0086866902237927
GO:BP GO:0055065 metal ion homeostasis 0.00205518402673153 667 93 12 0.129032258064516 0.0179910044977511
GO:BP GO:0010810 regulation of cell-substrate adhesion 0.0020789586360123 222 42 5 0.119047619047619 0.0225225225225225
GO:BP GO:1902531 regulation of intracellular signal transduction 0.00213132496913854 1842 82 20 0.24390243902439 0.01085776330076
GO:BP GO:0007010 cytoskeleton organization 0.0021928719362779 1423 129 23 0.178294573643411 0.0161630358397751
GO:BP GO:0009605 response to external stimulus 0.00220581721744641 2944 91 29 0.318681318681319 0.00985054347826087
GO:BP GO:0012501 programmed cell death 0.00225752617531108 2143 88 23 0.261363636363636 0.0107326178254783
GO:BP GO:2000026 regulation of multicellular organismal development 0.00229029736646905 1447 59 14 0.23728813559322 0.00967519004837595
GO:BP GO:0002703 regulation of leukocyte mediated immunity 0.00229128430081963 205 73 6 0.0821917808219178 0.0292682926829268
GO:BP GO:0010941 regulation of cell death 0.00229128430081963 1720 88 20 0.227272727272727 0.0116279069767442
GO:BP GO:0030042 actin filament depolymerization 0.00230012640784511 62 82 4 0.0487804878048781 0.0645161290322581
GO:BP GO:0022407 regulation of cell-cell adhesion 0.00231468831235588 445 82 9 0.109756097560976 0.0202247191011236
GO:BP GO:0060761 negative regulation of response to cytokine stimulus 0.00231468831235588 88 58 4 0.0689655172413793 0.0454545454545455
GO:BP GO:1904894 positive regulation of receptor signaling pathway via STAT 0.00232405795399501 50 40 3 0.075 0.06
GO:BP GO:0001503 ossification 0.00237249534107751 417 24 5 0.208333333333333 0.0119904076738609
GO:BP GO:0045595 regulation of cell differentiation 0.00246643036508006 1679 46 13 0.282608695652174 0.00774270399047052
GO:BP GO:0010171 body morphogenesis 0.00249770508147168 49 42 3 0.0714285714285714 0.0612244897959184
GO:BP GO:0006875 cellular metal ion homeostasis 0.00251812745616522 593 50 8 0.16 0.0134907251264755
GO:BP GO:1905517 macrophage migration 0.00252522402385176 56 37 3 0.0810810810810811 0.0535714285714286
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.00254727805865847 1455 46 12 0.260869565217391 0.00824742268041237
GO:BP GO:0010628 positive regulation of gene expression 0.00254741195137126 1160 10 5 0.5 0.00431034482758621
GO:BP GO:0046718 viral entry into host cell 0.00261785054487629 141 38 4 0.105263157894737 0.0283687943262411
GO:BP GO:0032970 regulation of actin filament-based process 0.00262000490332232 406 39 6 0.153846153846154 0.0147783251231527
GO:BP GO:0002009 morphogenesis of an epithelium 0.00268790038262196 560 29 6 0.206896551724138 0.0107142857142857
GO:BP GO:0006935 chemotaxis 0.00268790038262196 653 71 10 0.140845070422535 0.0153139356814701
GO:BP GO:0031100 animal organ regeneration 0.00270436458510303 77 129 5 0.0387596899224806 0.0649350649350649
GO:BP GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 0.00271274085309062 83 26 3 0.115384615384615 0.036144578313253
GO:BP GO:0042330 taxis 0.00275423465482192 656 71 10 0.140845070422535 0.0152439024390244
GO:BP GO:0010595 positive regulation of endothelial cell migration 0.00285139182060659 138 73 5 0.0684931506849315 0.036231884057971
GO:BP GO:0051051 negative regulation of transport 0.0028527008606285 474 80 9 0.1125 0.0189873417721519
GO:BP GO:0052547 regulation of peptidase activity 0.0028527008606285 467 118 11 0.0932203389830508 0.0235546038543897
GO:BP GO:0050673 epithelial cell proliferation 0.0029198577935327 460 13 4 0.307692307692308 0.00869565217391304
GO:BP GO:0017157 regulation of exocytosis 0.00297525147174913 207 77 6 0.0779220779220779 0.0289855072463768
GO:BP GO:0062197 cellular response to chemical stress 0.00298518395247607 365 127 10 0.078740157480315 0.0273972602739726
GO:BP GO:0070482 response to oxygen levels 0.00298518395247607 408 26 5 0.192307692307692 0.0122549019607843
GO:BP GO:0045824 negative regulation of innate immune response 0.00300519665223135 66 34 3 0.0882352941176471 0.0454545454545455
GO:BP GO:0001935 endothelial cell proliferation 0.00303876114652318 204 28 4 0.142857142857143 0.0196078431372549
GO:BP GO:0051049 regulation of transport 0.00309881018698789 1809 80 19 0.2375 0.0105030403537866
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 0.00315318237396042 223 26 4 0.153846153846154 0.0179372197309417
GO:BP GO:0008585 female gonad development 0.0034323858882268 96 110 5 0.0454545454545455 0.0520833333333333
GO:BP GO:0044409 entry into host 0.0034323858882268 154 38 4 0.105263157894737 0.025974025974026
GO:BP GO:0070374 positive regulation of ERK1 and ERK2 cascade 0.00348020016167811 215 77 6 0.0779220779220779 0.027906976744186
GO:BP GO:0043085 positive regulation of catalytic activity 0.00348020016167811 1418 118 21 0.177966101694915 0.0148095909732017
GO:BP GO:0045920 negative regulation of exocytosis 0.00348020016167811 31 77 3 0.038961038961039 0.0967741935483871
GO:BP GO:0032501 multicellular organismal process 0.00348020016167811 7946 136 80 0.588235294117647 0.0100679587213692
GO:BP GO:0048762 mesenchymal cell differentiation 0.00348020016167811 234 46 5 0.108695652173913 0.0213675213675214
GO:BP GO:0001959 regulation of cytokine-mediated signaling pathway 0.00348020016167811 184 58 5 0.0862068965517241 0.0271739130434783
GO:BP GO:0008217 regulation of blood pressure 0.00354798176386214 193 86 6 0.0697674418604651 0.0310880829015544
GO:BP GO:0034330 cell junction organization 0.0035891065579985 722 80 11 0.1375 0.0152354570637119
GO:BP GO:0001704 formation of primary germ layer 0.0035891065579985 123 135 6 0.0444444444444444 0.0487804878048781
GO:BP GO:0001541 ovarian follicle development 0.00361086495267038 54 110 4 0.0363636363636364 0.0740740740740741
GO:BP GO:0009628 response to abiotic stimulus 0.00365552955411745 1261 55 12 0.218181818181818 0.00951625693893735
GO:BP GO:0035722 interleukin-12-mediated signaling pathway 0.00374426487516825 47 129 4 0.0310077519379845 0.0851063829787234
GO:BP GO:0007015 actin filament organization 0.00374426487516825 445 129 11 0.0852713178294574 0.0247191011235955
GO:BP GO:0110053 regulation of actin filament organization 0.00374426487516825 284 39 5 0.128205128205128 0.0176056338028169
GO:BP GO:0045861 negative regulation of proteolysis 0.00374426487516825 359 110 9 0.0818181818181818 0.0250696378830084
GO:BP GO:0002548 monocyte chemotaxis 0.00374426487516825 67 37 3 0.0810810810810811 0.0447761194029851
GO:BP GO:0070555 response to interleukin-1 0.00374426487516825 215 110 7 0.0636363636363636 0.0325581395348837
GO:BP GO:0055114 obsolete oxidation-reduction process 0.00376889272368596 745 132 15 0.113636363636364 0.0201342281879195
GO:BP GO:0070613 regulation of protein processing 0.00382281156465347 66 38 3 0.0789473684210526 0.0454545454545455
GO:BP GO:0043279 response to alkaloid 0.00383539484679214 111 55 4 0.0727272727272727 0.036036036036036
GO:BP GO:0071674 mononuclear cell migration 0.00384793528440192 191 58 5 0.0862068965517241 0.0261780104712042
GO:BP GO:0014075 response to amine 0.00390432030737825 46 55 3 0.0545454545454545 0.0652173913043478
GO:BP GO:0046545 development of primary female sexual characteristics 0.00398902744111402 101 110 5 0.0454545454545455 0.0495049504950495
GO:BP GO:0030162 regulation of proteolysis 0.00404364112821076 752 118 14 0.11864406779661 0.0186170212765957
GO:BP GO:0051649 establishment of localization in cell 0.00404364112821076 2813 17 9 0.529411764705882 0.00319943121222894
GO:BP GO:0061028 establishment of endothelial barrier 0.00408658044872699 50 125 4 0.032 0.08
GO:BP GO:1903317 regulation of protein maturation 0.00408658044872699 68 38 3 0.0789473684210526 0.0441176470588235
GO:BP GO:0032943 mononuclear cell proliferation 0.00408658044872699 297 135 9 0.0666666666666667 0.0303030303030303
GO:BP GO:0044093 positive regulation of molecular function 0.00414787673177366 1771 111 23 0.207207207207207 0.012987012987013
GO:BP GO:0071349 cellular response to interleukin-12 0.00422370083731698 49 129 4 0.0310077519379845 0.0816326530612245
GO:BP GO:0060759 regulation of response to cytokine stimulus 0.00429832894198223 197 58 5 0.0862068965517241 0.0253807106598985
GO:BP GO:0003013 circulatory system process 0.00429832894198223 637 93 11 0.118279569892473 0.0172684458398744
GO:BP GO:1902905 positive regulation of supramolecular fiber organization 0.00433846308031802 214 82 6 0.0731707317073171 0.0280373831775701
GO:BP GO:0060627 regulation of vesicle-mediated transport 0.00448911553353096 536 77 9 0.116883116883117 0.0167910447761194
GO:BP GO:0043410 positive regulation of MAPK cascade 0.00448911553353096 539 110 11 0.1 0.0204081632653061
GO:BP GO:0070671 response to interleukin-12 0.00448911553353096 50 129 4 0.0310077519379845 0.08
GO:BP GO:0050671 positive regulation of lymphocyte proliferation 0.00455503990959171 141 82 5 0.0609756097560976 0.0354609929078014
GO:BP GO:0045926 negative regulation of growth 0.00455621141015842 255 46 5 0.108695652173913 0.0196078431372549
GO:BP GO:0016486 peptide hormone processing 0.00455621141015842 35 78 3 0.0384615384615385 0.0857142857142857
GO:BP GO:0030336 negative regulation of cell migration 0.00455621141015842 353 51 6 0.117647058823529 0.0169971671388102
GO:BP GO:0048008 platelet-derived growth factor receptor signaling pathway 0.00455621141015842 59 110 4 0.0363636363636364 0.0677966101694915
GO:BP GO:0010954 positive regulation of protein processing 0.00455621141015842 25 110 3 0.0272727272727273 0.12
GO:BP GO:0008219 cell death 0.00458712911562891 2292 88 23 0.261363636363636 0.0100349040139616
GO:BP GO:0048729 tissue morphogenesis 0.00458712911562891 667 135 14 0.103703703703704 0.0209895052473763
GO:BP GO:0032946 positive regulation of mononuclear cell proliferation 0.00459998464222735 142 82 5 0.0609756097560976 0.0352112676056338
GO:BP GO:0048754 branching morphogenesis of an epithelial tube 0.00459998464222735 151 118 6 0.0508474576271186 0.0397350993377483
GO:BP GO:0070233 negative regulation of T cell apoptotic process 0.00468964518218944 21 134 3 0.0223880597014925 0.142857142857143
GO:BP GO:1990830 cellular response to leukemia inhibitory factor 0.00471302721083586 89 74 4 0.0540540540540541 0.0449438202247191
GO:BP GO:0044281 small molecule metabolic process 0.00473191493676024 1921 137 28 0.204379562043796 0.0145757418011452
GO:BP GO:0072657 protein localization to membrane 0.00477612323412333 665 77 10 0.12987012987013 0.0150375939849624
GO:BP GO:0140448 signaling receptor ligand precursor processing 0.00477612323412333 36 78 3 0.0384615384615385 0.0833333333333333
GO:BP GO:0043627 response to estrogen 0.00477612323412333 78 36 3 0.0833333333333333 0.0384615384615385
GO:BP GO:1990823 response to leukemia inhibitory factor 0.00480800541452042 90 74 4 0.0540540540540541 0.0444444444444444
GO:BP GO:0052126 movement in host environment 0.00480800541452042 177 38 4 0.105263157894737 0.0225988700564972
GO:BP GO:0009636 response to toxic substance 0.00485770838532596 243 75 6 0.08 0.0246913580246914
GO:BP GO:0051452 intracellular pH reduction 0.00499131545519987 56 51 3 0.0588235294117647 0.0535714285714286
GO:BP GO:0072676 lymphocyte migration 0.00508508554212357 117 58 4 0.0689655172413793 0.0341880341880342
GO:BP GO:0008015 blood circulation 0.00510536978683243 553 93 10 0.10752688172043 0.0180831826401447
GO:BP GO:0030097 hemopoiesis 0.00510775170461809 928 135 17 0.125925925925926 0.0183189655172414
GO:BP GO:0002696 positive regulation of leukocyte activation 0.00512041162786217 412 82 8 0.0975609756097561 0.0194174757281553
GO:BP GO:0051249 regulation of lymphocyte activation 0.00512041162786217 518 82 9 0.109756097560976 0.0173745173745174
GO:BP GO:0051241 negative regulation of multicellular organismal process 0.00512041162786217 1160 46 10 0.217391304347826 0.00862068965517241
GO:BP GO:0051604 protein maturation 0.00516156034137621 306 110 8 0.0727272727272727 0.0261437908496732
GO:BP GO:0050778 positive regulation of immune response 0.0052109456380682 753 82 11 0.134146341463415 0.0146082337317397
GO:BP GO:2000146 negative regulation of cell motility 0.0052319212103062 369 51 6 0.117647058823529 0.016260162601626
GO:BP GO:1903319 positive regulation of protein maturation 0.00523438572048607 27 110 3 0.0272727272727273 0.111111111111111
GO:BP GO:0052548 regulation of endopeptidase activity 0.0052554347859694 437 118 10 0.0847457627118644 0.022883295194508
GO:BP GO:0016485 protein processing 0.00526832724849688 235 110 7 0.0636363636363636 0.0297872340425532
GO:BP GO:0044272 sulfur compound biosynthetic process 0.00529069597135807 193 134 7 0.0522388059701493 0.0362694300518135
GO:BP GO:0034329 cell junction assembly 0.00529069597135807 438 78 8 0.102564102564103 0.0182648401826484
GO:BP GO:0045851 pH reduction 0.0054499630313558 59 51 3 0.0588235294117647 0.0508474576271186
GO:BP GO:0090109 regulation of cell-substrate junction assembly 0.00547490370208218 64 110 4 0.0363636363636364 0.0625
GO:BP GO:0010638 positive regulation of organelle organization 0.00547490370208218 603 136 13 0.0955882352941176 0.021558872305141
GO:BP GO:0051893 regulation of focal adhesion assembly 0.00547490370208218 64 110 4 0.0363636363636364 0.0625
GO:BP GO:0007264 small GTPase mediated signal transduction 0.00548063256488115 515 139 12 0.0863309352517986 0.0233009708737864
GO:BP GO:0050886 endocrine process 0.00549955728827666 82 86 4 0.0465116279069767 0.0487804878048781
GO:BP GO:0051495 positive regulation of cytoskeleton organization 0.00552468265917218 231 82 6 0.0731707317073171 0.025974025974026
GO:BP GO:0098656 anion transmembrane transport 0.00555602514785059 550 79 9 0.113924050632911 0.0163636363636364
GO:BP GO:0051271 negative regulation of cellular component movement 0.00555602514785059 377 51 6 0.117647058823529 0.0159151193633952
GO:BP GO:0050789 regulation of biological process 0.00560993742742696 12091 83 69 0.831325301204819 0.00570672400959391
GO:BP GO:0033993 response to lipid 0.00562418219255167 918 91 13 0.142857142857143 0.014161220043573
GO:BP GO:0033043 regulation of organelle organization 0.00562418219255167 1203 136 20 0.147058823529412 0.0166251039068994
GO:BP GO:0050867 positive regulation of cell activation 0.00568215147956544 424 82 8 0.0975609756097561 0.0188679245283019
GO:BP GO:0016043 cellular component organization 0.0057312962034663 6566 129 65 0.503875968992248 0.00989948218093207
GO:BP GO:0070661 leukocyte proliferation 0.0057312962034663 325 82 7 0.0853658536585366 0.0215384615384615
GO:BP GO:0048661 positive regulation of smooth muscle cell proliferation 0.0057312962034663 103 70 4 0.0571428571428571 0.0388349514563107
GO:BP GO:0046660 female sex differentiation 0.0057420046635478 115 110 5 0.0454545454545455 0.0434782608695652
GO:BP GO:0070665 positive regulation of leukocyte proliferation 0.0057985285711534 155 82 5 0.0609756097560976 0.032258064516129
GO:BP GO:0007160 cell-matrix adhesion 0.00598334017127561 235 114 7 0.0614035087719298 0.0297872340425532
GO:BP GO:0070997 neuron death 0.00598334017127561 365 74 7 0.0945945945945946 0.0191780821917808
GO:BP GO:0050920 regulation of chemotaxis 0.0059995207307224 226 86 6 0.0697674418604651 0.0265486725663717
GO:BP GO:1901879 regulation of protein depolymerization 0.00612872755672026 90 82 4 0.0487804878048781 0.0444444444444444
GO:BP GO:0097435 supramolecular fiber organization 0.00613719937725367 734 129 14 0.108527131782946 0.0190735694822888
GO:BP GO:0008064 regulation of actin polymerization or depolymerization 0.00630049111717202 193 39 4 0.102564102564103 0.0207253886010363
GO:BP GO:0030832 regulation of actin filament length 0.00640882720251719 194 39 4 0.102564102564103 0.0206185567010309
GO:BP GO:0051345 positive regulation of hydrolase activity 0.00648041804634689 783 95 12 0.126315789473684 0.0153256704980843
GO:BP GO:0002064 epithelial cell development 0.00650057298983786 218 125 7 0.056 0.0321100917431193
GO:BP GO:0019058 viral life cycle 0.00656066730003484 353 38 5 0.131578947368421 0.0141643059490085
GO:BP GO:0006536 glutamate metabolic process 0.00658503834688692 33 101 3 0.0297029702970297 0.0909090909090909
GO:BP GO:0150116 regulation of cell-substrate junction organization 0.00663938287477611 69 110 4 0.0363636363636364 0.0579710144927536
GO:BP GO:0060485 mesenchyme development 0.00665090829025124 291 46 5 0.108695652173913 0.0171821305841924
GO:BP GO:0007163 establishment or maintenance of cell polarity 0.00673763257031385 220 125 7 0.056 0.0318181818181818
GO:BP GO:1901652 response to peptide 0.00679729601932124 551 82 9 0.109756097560976 0.0163339382940109
GO:BP GO:1904035 regulation of epithelial cell apoptotic process 0.00680723869185648 105 73 4 0.0547945205479452 0.0380952380952381
GO:BP GO:0002832 negative regulation of response to biotic stimulus 0.00686666791994527 100 34 3 0.0882352941176471 0.03
GO:BP GO:0002573 myeloid leukocyte differentiation 0.00694039539886071 213 130 7 0.0538461538461538 0.0328638497652582
GO:BP GO:0001666 response to hypoxia 0.00698082381704442 367 10 3 0.3 0.00817438692098093
GO:BP GO:0045471 response to ethanol 0.00708214202818058 142 55 4 0.0727272727272727 0.028169014084507
GO:BP GO:0009064 glutamine family amino acid metabolic process 0.00738905041179309 78 101 4 0.0396039603960396 0.0512820512820513
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.00745385756998191 1645 82 17 0.207317073170732 0.0103343465045593
GO:BP GO:0009611 response to wounding 0.00745385756998191 674 43 7 0.162790697674419 0.0103857566765579
GO:BP GO:0019220 regulation of phosphate metabolic process 0.00745385756998191 1645 82 17 0.207317073170732 0.0103343465045593
GO:BP GO:2000106 regulation of leukocyte apoptotic process 0.00747928682817045 82 43 3 0.0697674418604651 0.0365853658536585
GO:BP GO:0036293 response to decreased oxygen levels 0.0076595028553763 382 10 3 0.3 0.00785340314136126
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 0.0076595028553763 240 118 7 0.0593220338983051 0.0291666666666667
GO:BP GO:0051693 actin filament capping 0.00786742067867981 44 82 3 0.0365853658536585 0.0681818181818182
GO:BP GO:0097529 myeloid leukocyte migration 0.00787022608866003 221 37 4 0.108108108108108 0.0180995475113122
GO:BP GO:0048468 cell development 0.00788711963912548 2100 83 20 0.240963855421687 0.00952380952380952
GO:BP GO:0002683 negative regulation of immune system process 0.00788711963912548 420 34 5 0.147058823529412 0.0119047619047619
GO:BP GO:0019538 protein metabolic process 0.00789343031662504 5808 107 50 0.467289719626168 0.00860881542699725
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.00801067064321762 366 39 5 0.128205128205128 0.0136612021857923
GO:BP GO:0050794 regulation of cellular process 0.00804799128897473 11473 83 66 0.795180722891566 0.00575263662511985
GO:BP GO:0018146 keratan sulfate biosynthetic process 0.00825878920187905 28 134 3 0.0223880597014925 0.107142857142857
GO:BP GO:1901889 negative regulation of cell junction assembly 0.00827338870031415 34 110 3 0.0272727272727273 0.0882352941176471
GO:BP GO:0045937 positive regulation of phosphate metabolic process 0.00828156014140848 1001 111 15 0.135135135135135 0.014985014985015
GO:BP GO:0031399 regulation of protein modification process 0.00828156014140848 1671 82 17 0.207317073170732 0.0101735487731897
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 0.00828156014140848 1001 111 15 0.135135135135135 0.014985014985015
GO:BP GO:0034109 homotypic cell-cell adhesion 0.00828156014140848 87 43 3 0.0697674418604651 0.0344827586206897
GO:BP GO:0098542 defense response to other organism 0.00828156014140848 1218 4 3 0.75 0.00246305418719212
GO:BP GO:0051701 biological process involved in interaction with host 0.00828156014140848 221 38 4 0.105263157894737 0.0180995475113122
GO:BP GO:0065007 biological regulation 0.00837395249068651 12809 74 64 0.864864864864865 0.00499648684518698
GO:BP GO:0072678 T cell migration 0.00846426182159586 67 125 4 0.032 0.0597014925373134
GO:BP GO:0061138 morphogenesis of a branching epithelium 0.00854302148924064 181 118 6 0.0508474576271186 0.0331491712707182
GO:BP GO:0007369 gastrulation 0.00863555085154828 185 21 3 0.142857142857143 0.0162162162162162
GO:BP GO:0009617 response to bacterium 0.00865202607084726 743 91 11 0.120879120879121 0.0148048452220727
GO:BP GO:0010466 negative regulation of peptidase activity 0.00865202607084726 267 110 7 0.0636363636363636 0.0262172284644195
GO:BP GO:0043200 response to amino acid 0.00883341625665822 115 74 4 0.0540540540540541 0.0347826086956522
GO:BP GO:0042102 positive regulation of T cell proliferation 0.00888524115990431 104 82 4 0.0487804878048781 0.0384615384615385
GO:BP GO:0042060 wound healing 0.00888524115990431 549 87 9 0.103448275862069 0.0163934426229508
GO:BP GO:0072659 protein localization to plasma membrane 0.00898803412760908 283 77 6 0.0779220779220779 0.0212014134275618
GO:BP GO:0072507 divalent inorganic cation homeostasis 0.009057258609526 516 93 9 0.0967741935483871 0.0174418604651163
GO:BP GO:0045616 regulation of keratinocyte differentiation 0.009057258609526 43 91 3 0.032967032967033 0.0697674418604651
GO:BP GO:0061756 leukocyte adhesion to vascular endothelial cell 0.009057258609526 56 70 3 0.0428571428571429 0.0535714285714286
GO:BP GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 0.009057258609526 198 110 6 0.0545454545454545 0.0303030303030303
GO:BP GO:0008154 actin polymerization or depolymerization 0.009057258609526 223 39 4 0.102564102564103 0.0179372197309417
GO:BP GO:0051251 positive regulation of lymphocyte activation 0.009057258609526 365 82 7 0.0853658536585366 0.0191780821917808
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.009057258609526 3483 6 5 0.833333333333333 0.00143554407120299
GO:BP GO:0030835 negative regulation of actin filament depolymerization 0.00908409104064024 48 82 3 0.0365853658536585 0.0625
GO:BP GO:0003073 regulation of systemic arterial blood pressure 0.00923223966638412 101 86 4 0.0465116279069767 0.0396039603960396
GO:BP GO:0045453 bone resorption 0.00924038897103203 68 128 4 0.03125 0.0588235294117647
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.0092577798649952 387 39 5 0.128205128205128 0.0129198966408269
GO:BP GO:0051493 regulation of cytoskeleton organization 0.0092577798649952 531 128 11 0.0859375 0.0207156308851224
GO:BP GO:0060562 epithelial tube morphogenesis 0.00945121502280269 329 118 8 0.0677966101694915 0.0243161094224924
GO:BP GO:0042445 hormone metabolic process 0.0094907042834147 228 97 6 0.0618556701030928 0.0263157894736842
GO:BP GO:0030856 regulation of epithelial cell differentiation 0.00949488027604402 164 91 5 0.0549450549450549 0.0304878048780488
GO:BP GO:0097190 apoptotic signaling pathway 0.00961153772564644 600 26 5 0.192307692307692 0.00833333333333333
GO:BP GO:0007162 negative regulation of cell adhesion 0.0098470113146543 304 14 3 0.214285714285714 0.00986842105263158
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 0.0098600019023971 2255 91 22 0.241758241758242 0.00975609756097561
GO:BP GO:0033273 response to vitamin 0.00992220749210802 98 91 4 0.043956043956044 0.0408163265306122
GO:BP GO:0007265 Ras protein signal transduction 0.009929613135297 349 139 9 0.0647482014388489 0.0257879656160458
GO:BP GO:0045165 cell fate commitment 0.009929613135297 267 34 4 0.117647058823529 0.0149812734082397
GO:BP GO:0031589 cell-substrate adhesion 0.0100091981457252 367 42 5 0.119047619047619 0.0136239782016349
GO:BP GO:0070229 negative regulation of lymphocyte apoptotic process 0.0100110556717044 31 134 3 0.0223880597014925 0.0967741935483871
GO:BP GO:0071320 cellular response to cAMP 0.0101724404446834 54 77 3 0.038961038961039 0.0555555555555556
GO:BP GO:0071840 cellular component organization or biogenesis 0.010340375879011 6760 129 65 0.503875968992248 0.00961538461538462
GO:BP GO:0046651 lymphocyte proliferation 0.0105134496487254 294 135 8 0.0592592592592593 0.0272108843537415
GO:BP GO:0002698 negative regulation of immune effector process 0.0105240058125173 125 34 3 0.0882352941176471 0.024
GO:BP GO:1902117 positive regulation of organelle assembly 0.0108446246875093 68 136 4 0.0294117647058824 0.0588235294117647
GO:BP GO:0001763 morphogenesis of a branching structure 0.0110817476502963 195 118 6 0.0508474576271186 0.0307692307692308
GO:BP GO:0045596 negative regulation of cell differentiation 0.0110827636603785 697 46 7 0.152173913043478 0.0100430416068867
GO:BP GO:1904019 epithelial cell apoptotic process 0.0111521788786349 128 73 4 0.0547945205479452 0.03125
GO:BP GO:0048041 focal adhesion assembly 0.0111746697011214 85 110 4 0.0363636363636364 0.0470588235294118
GO:BP GO:0014910 regulation of smooth muscle cell migration 0.0111746697011214 85 110 4 0.0363636363636364 0.0470588235294118
GO:BP GO:0042339 keratan sulfate metabolic process 0.0114272228482144 33 134 3 0.0223880597014925 0.0909090909090909
GO:BP GO:0048771 tissue remodeling 0.0114287112405369 186 24 3 0.125 0.0161290322580645
GO:BP GO:0002687 positive regulation of leukocyte migration 0.0119000994978534 137 70 4 0.0571428571428571 0.0291970802919708
GO:BP GO:0009893 positive regulation of metabolic process 0.0119420071002807 3783 6 5 0.833333333333333 0.00132170235263019
GO:BP GO:0051261 protein depolymerization 0.0119420071002807 117 82 4 0.0487804878048781 0.0341880341880342
GO:BP GO:0008584 male gonad development 0.0119597671887039 142 32 3 0.09375 0.0211267605633803
GO:BP GO:0071347 cellular response to interleukin-1 0.0119597671887039 185 87 5 0.0574712643678161 0.027027027027027
GO:BP GO:0003333 amino acid transmembrane transport 0.0119597671887039 96 47 3 0.0638297872340425 0.03125
GO:BP GO:0051453 regulation of intracellular pH 0.0121191988665291 89 51 3 0.0588235294117647 0.0337078651685393
GO:BP GO:0046546 development of primary male sexual characteristics 0.0121412535847983 143 32 3 0.09375 0.020979020979021
GO:BP GO:0043271 negative regulation of ion transport 0.0122213148797212 349 47 5 0.106382978723404 0.0143266475644699
GO:BP GO:1990266 neutrophil migration 0.0122693573658042 124 37 3 0.0810810810810811 0.0241935483870968
GO:BP GO:0051094 positive regulation of developmental process 0.0122693573658042 1341 80 14 0.175 0.0104399701715138
GO:BP GO:1901214 regulation of neuron death 0.0122693573658042 323 74 6 0.0810810810810811 0.0185758513931889
GO:BP GO:0000096 sulfur amino acid metabolic process 0.0122855392582979 38 121 3 0.0247933884297521 0.0789473684210526
GO:BP GO:0010717 regulation of epithelial to mesenchymal transition 0.0122874785369223 102 45 3 0.0666666666666667 0.0294117647058824
GO:BP GO:0031333 negative regulation of protein-containing complex assembly 0.012446419556609 147 111 5 0.045045045045045 0.0340136054421769
GO:BP GO:0071887 leukocyte apoptotic process 0.0125619688198165 108 43 3 0.0697674418604651 0.0277777777777778
GO:BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 0.0126221235560698 185 89 5 0.0561797752808989 0.027027027027027
GO:BP GO:0002042 cell migration involved in sprouting angiogenesis 0.0126221235560698 104 45 3 0.0666666666666667 0.0288461538461538
GO:BP GO:0006835 dicarboxylic acid transport 0.0126221235560698 99 47 3 0.0638297872340425 0.0303030303030303
GO:BP GO:0050870 positive regulation of T cell activation 0.0126221235560698 219 110 6 0.0545454545454545 0.0273972602739726
GO:BP GO:0000902 cell morphogenesis 0.0126221235560698 1037 51 9 0.176470588235294 0.00867888138862102
GO:BP GO:0006749 glutathione metabolic process 0.0126221235560698 63 74 3 0.0405405405405405 0.0476190476190476
GO:BP GO:0002699 positive regulation of immune effector process 0.012681633289317 215 77 5 0.0649350649350649 0.0232558139534884
GO:BP GO:1904892 regulation of receptor signaling pathway via STAT 0.0127296705780533 118 40 3 0.075 0.0254237288135593
GO:BP GO:0051098 regulation of binding 0.0128658411869023 365 28 4 0.142857142857143 0.010958904109589
GO:BP GO:0001101 response to acid chemical 0.0128659637239973 135 74 4 0.0540540540540541 0.0296296296296296
GO:BP GO:0098754 detoxification 0.0130686461117231 134 75 4 0.0533333333333333 0.0298507462686567
GO:BP GO:0006790 sulfur compound metabolic process 0.0130686461117231 386 134 9 0.0671641791044776 0.0233160621761658
GO:BP GO:0070232 regulation of T cell apoptotic process 0.0132680680500635 36 134 3 0.0223880597014925 0.0833333333333333
GO:BP GO:0046324 regulation of glucose import 0.0133817697496977 61 79 3 0.0379746835443038 0.0491803278688525
GO:BP GO:0030641 regulation of cellular pH 0.0134864678790713 95 51 3 0.0588235294117647 0.0315789473684211
GO:BP GO:0043244 regulation of protein-containing complex disassembly 0.0135784508749635 125 39 3 0.0769230769230769 0.024
GO:BP GO:0051384 response to glucocorticoid 0.0136105008256361 146 70 4 0.0571428571428571 0.0273972602739726
GO:BP GO:0014909 smooth muscle cell migration 0.0137191676567091 93 110 4 0.0363636363636364 0.043010752688172
GO:BP GO:0030224 monocyte differentiation 0.0139516792707741 38 130 3 0.0230769230769231 0.0789473684210526
GO:BP GO:0051707 response to other organism 0.0139516792707741 1592 4 3 0.75 0.00188442211055276
GO:BP GO:0031401 positive regulation of protein modification process 0.0139516792707741 1074 80 12 0.15 0.0111731843575419
GO:BP GO:0043207 response to external biotic stimulus 0.0139516792707741 1594 4 3 0.75 0.00188205771643664
GO:BP GO:0001501 skeletal system development 0.0139516792707741 504 67 7 0.104477611940299 0.0138888888888889
GO:BP GO:0050678 regulation of epithelial cell proliferation 0.0141927371392942 401 13 3 0.230769230769231 0.00748129675810474
GO:BP GO:1903961 positive regulation of anion transmembrane transport 0.014259202689339 63 79 3 0.0379746835443038 0.0476190476190476
GO:BP GO:0019229 regulation of vasoconstriction 0.0143621687482098 64 78 3 0.0384615384615385 0.046875
GO:BP GO:0032273 positive regulation of protein polymerization 0.0144090328604026 141 122 5 0.040983606557377 0.0354609929078014
GO:BP GO:0051668 localization within membrane 0.0144274687250473 77 65 3 0.0461538461538462 0.038961038961039
GO:BP GO:0031667 response to nutrient levels 0.0144710422527264 482 110 9 0.0818181818181818 0.0186721991701245
GO:BP GO:0009607 response to biotic stimulus 0.0145170873674684 1626 4 3 0.75 0.0018450184501845
GO:BP GO:0050679 positive regulation of epithelial cell proliferation 0.0146536314211305 213 118 6 0.0508474576271186 0.028169014084507
GO:BP GO:0035296 regulation of tube diameter 0.0146616437600035 135 78 4 0.0512820512820513 0.0296296296296296
GO:BP GO:0097746 blood vessel diameter maintenance 0.0146616437600035 135 78 4 0.0512820512820513 0.0296296296296296
GO:BP GO:0035150 regulation of tube size 0.0149642994557415 136 78 4 0.0512820512820513 0.0294117647058824
GO:BP GO:0010565 regulation of cellular ketone metabolic process 0.0150381483573132 194 55 4 0.0727272727272727 0.0206185567010309
GO:BP GO:0002285 lymphocyte activation involved in immune response 0.0153139383087637 190 134 6 0.0447761194029851 0.0315789473684211
GO:BP GO:1901654 response to ketone 0.0153406363399178 204 125 6 0.048 0.0294117647058824
GO:BP GO:0046661 male sex differentiation 0.0153406363399178 163 32 3 0.09375 0.0184049079754601
GO:BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0155399543396959 217 118 6 0.0508474576271186 0.0276497695852535
GO:BP GO:0001936 regulation of endothelial cell proliferation 0.0155399543396959 188 28 3 0.107142857142857 0.0159574468085106
GO:BP GO:0006885 regulation of pH 0.0157845646341626 103 51 3 0.0588235294117647 0.029126213592233
GO:BP GO:0060193 positive regulation of lipase activity 0.0158046435060718 75 70 3 0.0428571428571429 0.04
GO:BP GO:0071417 cellular response to organonitrogen compound 0.0159816911734036 666 82 9 0.109756097560976 0.0135135135135135
GO:BP GO:1990778 protein localization to cell periphery 0.0161090590716182 338 77 6 0.0779220779220779 0.0177514792899408
GO:BP GO:0042113 B cell activation 0.0166281883743979 330 34 4 0.117647058823529 0.0121212121212121
GO:BP GO:0014911 positive regulation of smooth muscle cell migration 0.0166963336584571 49 110 3 0.0272727272727273 0.0612244897959184
GO:BP GO:1903305 regulation of regulated secretory pathway 0.0167016049359604 144 77 4 0.051948051948052 0.0277777777777778
GO:BP GO:0007044 cell-substrate junction assembly 0.0168481041339874 101 110 4 0.0363636363636364 0.0396039603960396
GO:BP GO:0031960 response to corticosteroid 0.0168481041339874 165 110 5 0.0454545454545455 0.0303030303030303
GO:BP GO:2001056 positive regulation of cysteine-type endopeptidase activity 0.0168857796953808 154 118 5 0.0423728813559322 0.0324675324675325
GO:BP GO:0071456 cellular response to hypoxia 0.0168857796953808 212 26 3 0.115384615384615 0.0141509433962264
GO:BP GO:0032102 negative regulation of response to external stimulus 0.0169372008513917 406 87 7 0.0804597701149425 0.0172413793103448
GO:BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.0170765979675619 363 73 6 0.0821917808219178 0.0165289256198347
GO:BP GO:0060249 anatomical structure homeostasis 0.0171769518551955 482 24 4 0.166666666666667 0.00829875518672199
GO:BP GO:1903530 regulation of secretion by cell 0.0172058147430471 588 77 8 0.103896103896104 0.0136054421768707
GO:BP GO:0001934 positive regulation of protein phosphorylation 0.0172058147430471 840 79 10 0.126582278481013 0.0119047619047619
GO:BP GO:0043393 regulation of protein binding 0.0173470100358811 199 28 3 0.107142857142857 0.0150753768844221
GO:BP GO:0034284 response to monosaccharide 0.0173590620367635 215 26 3 0.115384615384615 0.013953488372093
GO:BP GO:0045088 regulation of innate immune response 0.0174009313652613 309 37 4 0.108108108108108 0.0129449838187702
GO:BP GO:0060326 cell chemotaxis 0.0175553422726483 310 37 4 0.108108108108108 0.0129032258064516
GO:BP GO:0097530 granulocyte migration 0.0176273244581704 151 37 3 0.0810810810810811 0.0198675496688742
GO:BP GO:0030837 negative regulation of actin filament polymerization 0.0177570131450894 68 82 3 0.0365853658536585 0.0441176470588235
GO:BP GO:0001932 regulation of protein phosphorylation 0.0177684367126235 1240 82 13 0.158536585365854 0.0104838709677419
GO:BP GO:0000041 transition metal ion transport 0.0182084727109667 129 89 4 0.0449438202247191 0.0310077519379845
GO:BP GO:0036294 cellular response to decreased oxygen levels 0.0183165956804619 222 26 3 0.115384615384615 0.0135135135135135
GO:BP GO:0050805 negative regulation of synaptic transmission 0.0183165956804619 71 80 3 0.0375 0.0422535211267606
GO:BP GO:0050863 regulation of T cell activation 0.0183165956804619 337 135 8 0.0592592592592593 0.0237388724035608
GO:BP GO:0120035 regulation of plasma membrane bounded cell projection organization 0.0183823153069825 638 122 11 0.0901639344262295 0.0172413793103448
GO:BP GO:0050670 regulation of lymphocyte proliferation 0.0184361825867257 230 82 5 0.0609756097560976 0.0217391304347826
GO:BP GO:0045604 regulation of epidermal cell differentiation 0.0184791191939442 63 91 3 0.032967032967033 0.0476190476190476
GO:BP GO:0070848 response to growth factor 0.0185278177111326 759 118 12 0.101694915254237 0.0158102766798419
GO:BP GO:0014812 muscle cell migration 0.0186038430712427 106 110 4 0.0363636363636364 0.0377358490566038
GO:BP GO:0009991 response to extracellular stimulus 0.0186515553355515 512 110 9 0.0818181818181818 0.017578125
GO:BP GO:1903531 negative regulation of secretion by cell 0.0186940478621235 152 77 4 0.051948051948052 0.0263157894736842
GO:BP GO:0072503 cellular divalent inorganic cation homeostasis 0.0187098467869309 497 93 8 0.0860215053763441 0.0160965794768612
GO:BP GO:0032944 regulation of mononuclear cell proliferation 0.0187847012493976 232 82 5 0.0609756097560976 0.021551724137931
GO:BP GO:0150115 cell-substrate junction organization 0.0190181817896523 107 110 4 0.0363636363636364 0.0373831775700935
GO:BP GO:0045124 regulation of bone resorption 0.0191461287721306 46 128 3 0.0234375 0.0652173913043478
GO:BP GO:0001654 eye development 0.0191461287721306 379 51 5 0.0980392156862745 0.0131926121372032
GO:BP GO:0045087 innate immune response 0.0193133267272119 998 38 7 0.184210526315789 0.00701402805611222
GO:BP GO:0046849 bone remodeling 0.019435942673042 93 128 4 0.03125 0.043010752688172
GO:BP GO:0014888 striated muscle adaptation 0.0195462125974536 55 108 3 0.0277777777777778 0.0545454545454545
GO:BP GO:0006575 cellular modified amino acid metabolic process 0.0195985277781783 199 97 5 0.0515463917525773 0.0251256281407035
GO:BP GO:0032271 regulation of protein polymerization 0.0196376688236726 236 82 5 0.0609756097560976 0.0211864406779661
GO:BP GO:0150063 visual system development 0.0196376688236726 383 51 5 0.0980392156862745 0.0130548302872063
GO:BP GO:0042327 positive regulation of phosphorylation 0.019730485881434 927 111 13 0.117117117117117 0.0140237324703344
GO:BP GO:0042098 T cell proliferation 0.019730485881434 205 135 6 0.0444444444444444 0.0292682926829268
GO:BP GO:0080134 regulation of response to stress 0.0198782452104963 1443 5 3 0.6 0.00207900207900208
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0198782452104963 253 110 6 0.0545454545454545 0.0237154150197628
GO:BP GO:0046323 glucose import 0.0198782452104963 76 79 3 0.0379746835443038 0.0394736842105263
GO:BP GO:0030004 cellular monovalent inorganic cation homeostasis 0.0198782452104963 118 51 3 0.0588235294117647 0.0254237288135593
GO:BP GO:1903131 mononuclear cell differentiation 0.0200534518169972 430 46 5 0.108695652173913 0.0116279069767442
GO:BP GO:0048880 sensory system development 0.0202425936798576 389 51 5 0.0980392156862745 0.012853470437018
GO:BP GO:0042325 regulation of phosphorylation 0.0204165489410356 1431 82 14 0.170731707317073 0.00978336827393431
GO:BP GO:0003018 vascular process in circulatory system 0.020542090833349 256 110 6 0.0545454545454545 0.0234375
GO:BP GO:0034766 negative regulation of ion transmembrane transport 0.0205699457956904 131 47 3 0.0638297872340425 0.0229007633587786
GO:BP GO:0071453 cellular response to oxygen levels 0.0205929877350117 240 26 3 0.115384615384615 0.0125
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 0.0205929877350117 88 70 3 0.0428571428571429 0.0340909090909091
GO:BP GO:1901880 negative regulation of protein depolymerization 0.0205929877350117 75 82 3 0.0365853658536585 0.04
GO:BP GO:0031344 regulation of cell projection organization 0.0205929877350117 656 122 11 0.0901639344262295 0.0167682926829268
GO:BP GO:0034763 negative regulation of transmembrane transport 0.0207886938723591 132 47 3 0.0638297872340425 0.0227272727272727
GO:BP GO:0010827 regulation of glucose transmembrane transport 0.0210427444828484 79 79 3 0.0379746835443038 0.0379746835443038
GO:BP GO:0007423 sensory organ development 0.0210822657197601 567 51 6 0.117647058823529 0.0105820105820106
GO:BP GO:0043436 oxoacid metabolic process 0.0211639010039128 1057 134 16 0.119402985074627 0.0151371807000946
GO:BP GO:0001894 tissue homeostasis 0.02195313832334 270 24 3 0.125 0.0111111111111111
GO:BP GO:0045682 regulation of epidermis development 0.0219624767411118 70 91 3 0.032967032967033 0.0428571428571429
GO:BP GO:0040008 regulation of growth 0.0221619543156093 681 103 10 0.0970873786407767 0.0146842878120411
GO:BP GO:1901699 cellular response to nitrogen compound 0.0221619543156093 724 82 9 0.109756097560976 0.0124309392265193
GO:BP GO:0010977 negative regulation of neuron projection development 0.0221619543156093 140 46 3 0.0652173913043478 0.0214285714285714
GO:BP GO:0030838 positive regulation of actin filament polymerization 0.0221619543156093 104 122 4 0.0327868852459016 0.0384615384615385
GO:BP GO:0048545 response to steroid hormone 0.0222730473232159 349 110 7 0.0636363636363636 0.0200573065902579
GO:BP GO:0016032 viral process 0.0223963058044306 942 138 15 0.108695652173913 0.0159235668789809
GO:BP GO:0043086 negative regulation of catalytic activity 0.0224488625016909 851 110 12 0.109090909090909 0.0141010575793184
GO:BP GO:0001570 vasculogenesis 0.0224488625016909 84 77 3 0.038961038961039 0.0357142857142857
GO:BP GO:0009612 response to mechanical stimulus 0.0224488625016909 218 133 6 0.0451127819548872 0.0275229357798165
GO:BP GO:0042310 vasoconstriction 0.0224488625016909 83 78 3 0.0384615384615385 0.036144578313253
GO:BP GO:0001819 positive regulation of cytokine production 0.0226127902074255 452 15 3 0.2 0.00663716814159292
GO:BP GO:0032880 regulation of protein localization 0.0226127902074255 922 43 7 0.162790697674419 0.00759219088937093
GO:BP GO:0070663 regulation of leukocyte proliferation 0.0226127902074255 251 82 5 0.0609756097560976 0.0199203187250996
GO:BP GO:0001938 positive regulation of endothelial cell proliferation 0.022722957283701 113 58 3 0.0517241379310345 0.0265486725663717
GO:BP GO:0050864 regulation of B cell activation 0.022722957283701 194 34 3 0.0882352941176471 0.0154639175257732
GO:BP GO:0071675 regulation of mononuclear cell migration 0.022722957283701 113 58 3 0.0517241379310345 0.0265486725663717
GO:BP GO:0061098 positive regulation of protein tyrosine kinase activity 0.0230314105192452 60 110 3 0.0272727272727273 0.05
GO:BP GO:0001889 liver development 0.0232517646717697 148 88 4 0.0454545454545455 0.027027027027027
GO:BP GO:0032092 positive regulation of protein binding 0.0233088157003785 85 78 3 0.0384615384615385 0.0352941176470588
GO:BP GO:0010639 negative regulation of organelle organization 0.023330395082934 361 82 6 0.0731707317073171 0.0166204986149584
GO:BP GO:0007005 mitochondrion organization 0.023330395082934 561 24 4 0.166666666666667 0.0071301247771836
GO:BP GO:0051017 actin filament bundle assembly 0.0233845062424636 161 129 5 0.0387596899224806 0.031055900621118
GO:BP GO:0048871 multicellular organismal homeostasis 0.0234192719322818 530 40 5 0.125 0.00943396226415094
GO:BP GO:0050730 regulation of peptidyl-tyrosine phosphorylation 0.0235746674036365 269 110 6 0.0545454545454545 0.0223048327137546
GO:BP GO:0051046 regulation of secretion 0.0238741299430525 647 77 8 0.103896103896104 0.0123647604327666
GO:BP GO:0032272 negative regulation of protein polymerization 0.0238741299430525 82 82 3 0.0365853658536585 0.0365853658536585
GO:BP GO:0046850 regulation of bone remodeling 0.0241031065065264 53 128 3 0.0234375 0.0566037735849057
GO:BP GO:0051338 regulation of transferase activity 0.0241464710546772 1035 140 16 0.114285714285714 0.0154589371980676
GO:BP GO:0061008 hepaticobiliary system development 0.0241550772615329 151 88 4 0.0454545454545455 0.0264900662251656
GO:BP GO:0071363 cellular response to growth factor stimulus 0.0243018925960194 731 114 11 0.0964912280701754 0.0150478796169631
GO:BP GO:0061572 actin filament bundle organization 0.0244045313744423 164 129 5 0.0387596899224806 0.0304878048780488
GO:BP GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 0.0246176959038785 760 110 11 0.1 0.0144736842105263
GO:BP GO:0030833 regulation of actin filament polymerization 0.0246176959038785 177 39 3 0.0769230769230769 0.0169491525423729
GO:BP GO:0097696 receptor signaling pathway via STAT 0.0246692411815998 184 73 4 0.0547945205479452 0.0217391304347826
GO:BP GO:0006082 organic acid metabolic process 0.0252313759363225 1090 134 16 0.119402985074627 0.0146788990825688
GO:BP GO:0007173 epidermal growth factor receptor signaling pathway 0.0252492788231177 123 110 4 0.0363636363636364 0.032520325203252
GO:BP GO:0051048 negative regulation of secretion 0.0252492788231177 176 77 4 0.051948051948052 0.0227272727272727
GO:BP GO:0043534 blood vessel endothelial cell migration 0.0253131473072168 186 73 4 0.0547945205479452 0.021505376344086
GO:BP GO:0071396 cellular response to lipid 0.0253131473072168 578 125 10 0.08 0.0173010380622837
GO:BP GO:0001837 epithelial to mesenchymal transition 0.0254894883500686 156 45 3 0.0666666666666667 0.0192307692307692
GO:BP GO:0044092 negative regulation of molecular function 0.0254894883500686 1219 110 15 0.136363636363636 0.0123051681706317
GO:BP GO:0008406 gonad development 0.0255236391752755 221 32 3 0.09375 0.0135746606334842
GO:BP GO:1904018 positive regulation of vasculature development 0.0255749873621568 187 73 4 0.0547945205479452 0.0213903743315508
GO:BP GO:0045766 positive regulation of angiogenesis 0.0255749873621568 187 73 4 0.0547945205479452 0.0213903743315508
GO:BP GO:0062012 regulation of small molecule metabolic process 0.02585003019203 447 137 9 0.0656934306569343 0.0201342281879195
GO:BP GO:0043242 negative regulation of protein-containing complex disassembly 0.0258840574539803 86 82 3 0.0365853658536585 0.0348837209302326
GO:BP GO:0060191 regulation of lipase activity 0.0259916448188618 101 70 3 0.0428571428571429 0.0297029702970297
GO:BP GO:0043269 regulation of ion transport 0.026187992952834 1379 80 13 0.1625 0.00942712110224801
GO:BP GO:0051347 positive regulation of transferase activity 0.0263808233985338 689 140 12 0.0857142857142857 0.0174165457184325
GO:BP GO:0045137 development of primary sexual characteristics 0.0267890454249437 227 32 3 0.09375 0.013215859030837
GO:BP GO:0050727 regulation of inflammatory response 0.0267890454249437 381 37 4 0.108108108108108 0.010498687664042
GO:BP GO:1905039 carboxylic acid transmembrane transport 0.0269377709144395 154 47 3 0.0638297872340425 0.0194805194805195
GO:BP GO:0097305 response to alcohol 0.0269770080506223 255 55 4 0.0727272727272727 0.0156862745098039
GO:BP GO:0071407 cellular response to organic cyclic compound 0.0270621203101694 587 125 10 0.08 0.0170357751277683
GO:BP GO:0010950 positive regulation of endopeptidase activity 0.0272318733317995 187 118 5 0.0423728813559322 0.0267379679144385
GO:BP GO:1903825 organic acid transmembrane transport 0.0272318733317995 155 47 3 0.0638297872340425 0.0193548387096774
GO:BP GO:0071495 cellular response to endogenous stimulus 0.0272318733317995 1422 114 17 0.149122807017544 0.0119549929676512
GO:BP GO:0051592 response to calcium ion 0.0272888489721045 151 93 4 0.043010752688172 0.0264900662251656
GO:BP GO:0006865 amino acid transport 0.0273162814679565 156 47 3 0.0638297872340425 0.0192307692307692
GO:BP GO:1903827 regulation of cellular protein localization 0.0275959984107949 572 129 10 0.0775193798449612 0.0174825174825175
GO:BP GO:0071356 cellular response to tumor necrosis factor 0.0276578426095413 306 73 5 0.0684931506849315 0.0163398692810458
GO:BP GO:0016525 negative regulation of angiogenesis 0.0277918507513361 161 46 3 0.0652173913043478 0.0186335403726708
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0277918507513361 470 110 8 0.0727272727272727 0.0170212765957447
GO:BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 0.0277918507513361 251 89 5 0.0561797752808989 0.0199203187250996
GO:BP GO:0009791 post-embryonic development 0.027854507915505 84 88 3 0.0340909090909091 0.0357142857142857
GO:BP GO:0006520 cellular amino acid metabolic process 0.0279552390340688 341 121 7 0.0578512396694215 0.0205278592375367
GO:BP GO:0010817 regulation of hormone levels 0.0281785463990241 536 97 8 0.0824742268041237 0.0149253731343284
GO:BP GO:0051090 regulation of DNA-binding transcription factor activity 0.0283810184669198 456 32 4 0.125 0.0087719298245614
GO:BP GO:2000181 negative regulation of blood vessel morphogenesis 0.0284345633377113 163 46 3 0.0652173913043478 0.0184049079754601
GO:BP GO:0006909 phagocytosis 0.0284559024677818 387 82 6 0.0731707317073171 0.0155038759689922
GO:BP GO:0043547 positive regulation of GTPase activity 0.0285112448294388 413 77 6 0.0779220779220779 0.0145278450363196
GO:BP GO:1901343 negative regulation of vasculature development 0.028668003136089 164 46 3 0.0652173913043478 0.0182926829268293
GO:BP GO:0042129 regulation of T cell proliferation 0.0287594545602475 176 82 4 0.0487804878048781 0.0227272727272727
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 0.0291174304781626 512 82 7 0.0853658536585366 0.013671875
GO:BP GO:0031032 actomyosin structure organization 0.0291334995942058 199 114 5 0.043859649122807 0.0251256281407035
GO:BP GO:1900076 regulation of cellular response to insulin stimulus 0.0291780778720439 69 110 3 0.0272727272727273 0.0434782608695652
GO:BP GO:0030041 actin filament polymerization 0.0292403287436018 196 39 3 0.0769230769230769 0.0153061224489796
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.0294987176375751 3087 82 23 0.280487804878049 0.00745059928733398
GO:BP GO:0098739 import across plasma membrane 0.0295019824844226 163 47 3 0.0638297872340425 0.0184049079754601
GO:BP GO:0002764 immune response-regulating signaling pathway 0.0296461838163691 515 82 7 0.0853658536585366 0.0135922330097087
GO:BP GO:0019752 carboxylic acid metabolic process 0.0296649160067824 1024 134 15 0.111940298507463 0.0146484375
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 0.0304970762401989 294 110 6 0.0545454545454545 0.0204081632653061
GO:BP GO:0061448 connective tissue development 0.0304970762401989 256 58 4 0.0689655172413793 0.015625
GO:BP GO:0042180 cellular ketone metabolic process 0.0306972760367215 271 55 4 0.0727272727272727 0.014760147601476
GO:BP GO:0046626 regulation of insulin receptor signaling pathway 0.0307353396243515 71 110 3 0.0272727272727273 0.0422535211267606
GO:BP GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 0.0307603578317107 135 110 4 0.0363636363636364 0.0296296296296296
GO:BP GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 0.0307603578317107 135 110 4 0.0363636363636364 0.0296296296296296
GO:BP GO:0044403 biological process involved in symbiotic interaction 0.0308688247011775 1001 138 15 0.108695652173913 0.014985014985015
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.0309576510976393 3083 6 4 0.666666666666667 0.00129743756081739
GO:BP GO:2000401 regulation of lymphocyte migration 0.0310555946851671 63 125 3 0.024 0.0476190476190476
GO:BP GO:0006793 phosphorus metabolic process 0.031579780767824 3114 82 23 0.280487804878049 0.00738599871547848
GO:BP GO:0002695 negative regulation of leukocyte activation 0.0315801539048945 188 80 4 0.05 0.0212765957446809
GO:BP GO:0060341 regulation of cellular localization 0.0316961105639582 851 10 3 0.3 0.00352526439482961
GO:BP GO:0060491 regulation of cell projection assembly 0.0317308996429116 192 122 5 0.040983606557377 0.0260416666666667
GO:BP GO:0038094 Fc-gamma receptor signaling pathway 0.0317702222769167 137 110 4 0.0363636363636364 0.0291970802919708
GO:BP GO:0051248 negative regulation of protein metabolic process 0.0319029766304719 1151 110 14 0.127272727272727 0.0121633362293658
GO:BP GO:0002831 regulation of response to biotic stimulus 0.031972425366888 415 37 4 0.108108108108108 0.00963855421686747
GO:BP GO:0008285 negative regulation of cell population proliferation 0.0320259214845447 790 20 4 0.2 0.00506329113924051
GO:BP GO:0046847 filopodium assembly 0.032228716667037 64 126 3 0.0238095238095238 0.046875
GO:BP GO:0034765 regulation of ion transmembrane transport 0.0325143496003408 583 93 8 0.0860215053763441 0.0137221269296741
GO:BP GO:0009056 catabolic process 0.0325633645026108 2744 10 5 0.5 0.00182215743440233
GO:BP GO:0030865 cortical cytoskeleton organization 0.0325633645026108 63 129 3 0.0232558139534884 0.0476190476190476
GO:BP GO:0051881 regulation of mitochondrial membrane potential 0.0327131538778865 74 110 3 0.0272727272727273 0.0405405405405405
GO:BP GO:1905475 regulation of protein localization to membrane 0.0333669964656704 201 77 4 0.051948051948052 0.0199004975124378
GO:BP GO:1901605 alpha-amino acid metabolic process 0.0333974061904073 198 121 5 0.0413223140495868 0.0252525252525253
GO:BP GO:0034762 regulation of transmembrane transport 0.0335290238170134 588 93 8 0.0860215053763441 0.0136054421768707
GO:BP GO:0002431 Fc receptor mediated stimulatory signaling pathway 0.0336356001743626 141 110 4 0.0363636363636364 0.0283687943262411
GO:BP GO:0034612 response to tumor necrosis factor 0.0336356001743626 331 73 5 0.0684931506849315 0.0151057401812689
GO:BP GO:0043549 regulation of kinase activity 0.0336356001743626 921 111 12 0.108108108108108 0.0130293159609121
GO:BP GO:0006518 peptide metabolic process 0.033746835822033 955 82 10 0.121951219512195 0.0104712041884817
GO:BP GO:0001558 regulation of cell growth 0.0337694253392819 426 103 7 0.0679611650485437 0.0164319248826291
GO:BP GO:0031348 negative regulation of defense response 0.0337694253392819 246 34 3 0.0882352941176471 0.0121951219512195
GO:BP GO:0010952 positive regulation of peptidase activity 0.0340815427145519 205 118 5 0.0423728813559322 0.024390243902439
GO:BP GO:0030595 leukocyte chemotaxis 0.0340815427145519 227 37 3 0.0810810810810811 0.013215859030837
GO:BP GO:0008361 regulation of cell size 0.0340815427145519 182 46 3 0.0652173913043478 0.0164835164835165
GO:BP GO:0007568 aging 0.0343155031709617 329 74 5 0.0675675675675676 0.0151975683890578
GO:BP GO:0031323 regulation of cellular metabolic process 0.0343335751046942 6269 58 29 0.5 0.00462593715106078
GO:BP GO:0055067 monovalent inorganic cation homeostasis 0.0344041061298202 165 51 3 0.0588235294117647 0.0181818181818182
GO:BP GO:0031325 positive regulation of cellular metabolic process 0.0355973772445283 3274 6 4 0.666666666666667 0.00122174709835064
GO:BP GO:0051091 positive regulation of DNA-binding transcription factor activity 0.035691548815899 270 32 3 0.09375 0.0111111111111111
GO:BP GO:0038127 ERBB signaling pathway 0.035691548815899 145 110 4 0.0363636363636364 0.0275862068965517
GO:BP GO:0043523 regulation of neuron apoptotic process 0.035691548815899 216 74 4 0.0540540540540541 0.0185185185185185
GO:BP GO:0042246 tissue regeneration 0.0357417378533737 80 107 3 0.0280373831775701 0.0375
GO:BP GO:0045862 positive regulation of proteolysis 0.0358656387800286 378 118 7 0.0593220338983051 0.0185185185185185
GO:BP GO:0033344 cholesterol efflux 0.0363278853361229 66 131 3 0.0229007633587786 0.0454545454545455
GO:BP GO:0031345 negative regulation of cell projection organization 0.0363364918651964 189 46 3 0.0652173913043478 0.0158730158730159
GO:BP GO:0016311 dephosphorylation 0.0364127070568126 508 110 8 0.0727272727272727 0.015748031496063
GO:BP GO:0007548 sex differentiation 0.0366639431977567 275 32 3 0.09375 0.0109090909090909
GO:BP GO:0006869 lipid transport 0.0367067492753805 480 94 7 0.074468085106383 0.0145833333333333
GO:BP GO:0051258 protein polymerization 0.0367394274478003 305 82 5 0.0609756097560976 0.0163934426229508
GO:BP GO:0043624 cellular protein complex disassembly 0.036995756729978 226 39 3 0.0769230769230769 0.0132743362831858
GO:BP GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0371663792813572 138 118 4 0.0338983050847458 0.0289855072463768
GO:BP GO:0043405 regulation of MAP kinase activity 0.0371663792813572 316 110 6 0.0545454545454545 0.0189873417721519
GO:BP GO:0030308 negative regulation of cell growth 0.0372715919481227 192 46 3 0.0652173913043478 0.015625
GO:BP GO:1904659 glucose transmembrane transport 0.0376623542019861 112 79 3 0.0379746835443038 0.0267857142857143
GO:BP GO:0044070 regulation of anion transport 0.0376659028263437 896 131 13 0.099236641221374 0.0145089285714286
GO:BP GO:0002705 positive regulation of leukocyte mediated immunity 0.0378803663826589 122 73 3 0.0410958904109589 0.0245901639344262
GO:BP GO:0045727 positive regulation of translation 0.0381135461321508 140 118 4 0.0338983050847458 0.0285714285714286
GO:BP GO:0044106 cellular amine metabolic process 0.0381416826884803 163 55 3 0.0545454545454545 0.0184049079754601
GO:BP GO:0002449 lymphocyte mediated immunity 0.0389093069452876 354 26 3 0.115384615384615 0.00847457627118644
GO:BP GO:0007507 heart development 0.0389854497107227 578 45 5 0.111111111111111 0.00865051903114187
GO:BP GO:0008645 hexose transmembrane transport 0.0390248228430152 115 79 3 0.0379746835443038 0.0260869565217391
GO:BP GO:0043010 camera-type eye development 0.0390963058425367 331 51 4 0.0784313725490196 0.0120845921450151
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.0392837493456837 1082 110 13 0.118181818181818 0.0120147874306839
GO:BP GO:0002040 sprouting angiogenesis 0.0395032338091551 204 45 3 0.0666666666666667 0.0147058823529412
GO:BP GO:0050866 negative regulation of cell activation 0.0395291100898112 211 80 4 0.05 0.018957345971564
GO:BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 0.0397965603375887 291 89 5 0.0561797752808989 0.0171821305841924
GO:BP GO:0009308 amine metabolic process 0.0399663673036465 168 55 3 0.0545454545454545 0.0178571428571429
GO:BP GO:0050807 regulation of synapse organization 0.0399663673036465 212 80 4 0.05 0.0188679245283019
GO:BP GO:0019216 regulation of lipid metabolic process 0.0399663673036465 419 137 8 0.0583941605839416 0.0190930787589499
GO:BP GO:0015749 monosaccharide transmembrane transport 0.0401520648989169 117 79 3 0.0379746835443038 0.0256410256410256
GO:BP GO:0044267 cellular protein metabolic process 0.0406162763413682 5229 87 35 0.402298850574713 0.00669344042838019
GO:BP GO:0032368 regulation of lipid transport 0.0407394772580833 167 56 3 0.0535714285714286 0.0179640718562874
GO:BP GO:1902115 regulation of organelle assembly 0.0407394772580833 192 136 5 0.0367647058823529 0.0260416666666667
GO:BP GO:0030010 establishment of cell polarity 0.040791331212505 142 66 3 0.0454545454545455 0.0211267605633803
GO:BP GO:0003008 system process 0.0409180063868315 2293 114 23 0.201754385964912 0.0100305276929786
GO:BP GO:0034219 carbohydrate transmembrane transport 0.0410135562191507 119 79 3 0.0379746835443038 0.0252100840336134
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 0.041064992660473 5848 12 8 0.666666666666667 0.00136798905608755
GO:BP GO:0019882 antigen processing and presentation 0.0429495630025024 234 114 5 0.043859649122807 0.0213675213675214
GO:BP GO:0032204 regulation of telomere maintenance 0.0433230524925197 82 118 3 0.0254237288135593 0.0365853658536585
GO:BP GO:0030168 platelet activation 0.0433230524925197 160 110 4 0.0363636363636364 0.025
GO:BP GO:0048732 gland development 0.0433614931792227 436 135 8 0.0592592592592593 0.018348623853211
GO:BP GO:0030001 metal ion transport 0.0434639555031242 514 93 7 0.0752688172043011 0.0136186770428016
GO:BP GO:0060255 regulation of macromolecule metabolic process 0.0436781439578607 6603 17 11 0.647058823529412 0.00166590943510526
GO:BP GO:0006468 protein phosphorylation 0.0442930258231298 1668 82 14 0.170731707317073 0.00839328537170264
GO:BP GO:0050803 regulation of synapse structure or activity 0.0443282434359775 223 80 4 0.05 0.0179372197309417
GO:BP GO:0048589 developmental growth 0.0446364280749806 649 58 6 0.103448275862069 0.00924499229583975
GO:BP GO:0006811 ion transport 0.0447332334257796 3661 94 28 0.297872340425532 0.00764818355640535
GO:BP GO:0015711 organic anion transport 0.0452558143660837 386 47 4 0.0851063829787234 0.0103626943005181
GO:BP GO:0043087 regulation of GTPase activity 0.0452558143660837 493 37 4 0.108108108108108 0.00811359026369168
GO:BP GO:0043648 dicarboxylic acid metabolic process 0.0459960027484501 99 101 3 0.0297029702970297 0.0303030303030303
GO:BP GO:0097581 lamellipodium organization 0.0459969258926434 91 110 3 0.0272727272727273 0.032967032967033
GO:BP GO:0080090 regulation of primary metabolic process 0.0460280147943559 6053 6 5 0.833333333333333 0.000826036676028416
GO:BP GO:0000904 cell morphogenesis involved in differentiation 0.0461704528461926 749 51 6 0.117647058823529 0.00801068090787717
GO:BP GO:0043434 response to peptide hormone 0.0465356998806356 462 82 6 0.0731707317073171 0.012987012987013
GO:BP GO:0006487 protein N-linked glycosylation 0.0472345112051491 76 134 3 0.0223880597014925 0.0394736842105263
GO:BP GO:0051402 neuron apoptotic process 0.0478974664309454 250 74 4 0.0540540540540541 0.016
GO:BP GO:0061097 regulation of protein tyrosine kinase activity 0.0494925745334004 95 110 3 0.0272727272727273 0.0315789473684211
GO:BP GO:0010876 lipid localization 0.0496250958904769 530 94 7 0.074468085106383 0.0132075471698113
GO:CC GO:0005615 extracellular space 5.72229361757221e-09 3594 90 45 0.5 0.0125208681135225
GO:CC GO:0005576 extracellular region 5.72229361757221e-09 4567 92 52 0.565217391304348 0.0113860302167725
GO:CC GO:0071944 cell periphery 8.24943447929846e-09 6169 93 61 0.655913978494624 0.00988815042956719
GO:CC GO:0031982 vesicle 1.69353400598915e-08 4055 114 55 0.482456140350877 0.0135635018495684
GO:CC GO:0009986 cell surface 4.30820388524045e-08 899 96 22 0.229166666666667 0.0244716351501669
GO:CC GO:0070062 extracellular exosome 2.92342186422758e-07 2176 88 31 0.352272727272727 0.0142463235294118
GO:CC GO:0005925 focal adhesion 4.51554176113048e-07 420 136 17 0.125 0.0404761904761905
GO:CC GO:0043230 extracellular organelle 4.51554176113048e-07 2263 88 31 0.352272727272727 0.0136986301369863
GO:CC GO:0030055 cell-substrate junction 4.51554176113048e-07 427 136 17 0.125 0.0398126463700234
GO:CC GO:1903561 extracellular vesicle 4.51554176113048e-07 2261 88 31 0.352272727272727 0.0137107474568775
GO:CC GO:0070161 anchoring junction 9.87523131218931e-07 836 136 23 0.169117647058824 0.027511961722488
GO:CC GO:0030312 external encapsulating structure 1.02095043501088e-06 563 26 9 0.346153846153846 0.0159857904085258
GO:CC GO:0031012 extracellular matrix 1.02095043501088e-06 562 26 9 0.346153846153846 0.0160142348754448
GO:CC GO:0097708 intracellular vesicle 1.04208006303888e-06 2428 114 37 0.324561403508772 0.0152388797364086
GO:CC GO:0031410 cytoplasmic vesicle 1.04208006303888e-06 2424 114 37 0.324561403508772 0.0152640264026403
GO:CC GO:0012505 endomembrane system 2.10384850975575e-06 4640 140 63 0.45 0.0135775862068966
GO:CC GO:0062023 collagen-containing extracellular matrix 2.57201997652337e-05 421 26 7 0.269230769230769 0.0166270783847981
GO:CC GO:0002102 podosome 2.57201997652337e-05 28 129 5 0.0387596899224806 0.178571428571429
GO:CC GO:0030667 secretory granule membrane 2.9327306717523e-05 303 88 10 0.113636363636364 0.033003300330033
GO:CC GO:0012506 vesicle membrane 3.62641797150318e-05 800 94 16 0.170212765957447 0.02
GO:CC GO:0005886 plasma membrane 3.98801800418172e-05 5681 129 64 0.496124031007752 0.0112656222496039
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.000113950338194673 779 94 15 0.159574468085106 0.0192554557124519
GO:CC GO:0030141 secretory granule 0.000136395518404274 851 88 15 0.170454545454545 0.0176263219741481
GO:CC GO:0030054 cell junction 0.000145931267517097 2105 129 32 0.248062015503876 0.0152019002375297
GO:CC GO:0009897 external side of plasma membrane 0.00018128819850809 408 83 10 0.120481927710843 0.0245098039215686
GO:CC GO:0005783 endoplasmic reticulum 0.000236619829420058 1982 140 32 0.228571428571429 0.0161453077699294
GO:CC GO:0031090 organelle membrane 0.000445112881842419 3612 140 47 0.335714285714286 0.0130121816168328
GO:CC GO:0005768 endosome 0.000445112881842419 987 138 20 0.144927536231884 0.0202634245187437
GO:CC GO:0099503 secretory vesicle 0.000522836236689795 1020 94 16 0.170212765957447 0.0156862745098039
GO:CC GO:0098552 side of membrane 0.00103779523940349 619 83 11 0.132530120481928 0.0177705977382876
GO:CC GO:0098588 bounding membrane of organelle 0.00190101831379655 2158 138 31 0.22463768115942 0.0143651529193698
GO:CC GO:0000323 lytic vacuole 0.00295172948550384 712 110 13 0.118181818181818 0.0182584269662921
GO:CC GO:0005764 lysosome 0.00295172948550384 712 110 13 0.118181818181818 0.0182584269662921
GO:CC GO:0098590 plasma membrane region 0.00298632016026494 1240 129 20 0.155038759689922 0.0161290322580645
GO:CC GO:0005765 lysosomal membrane 0.00298632016026494 383 83 8 0.0963855421686747 0.02088772845953
GO:CC GO:0098852 lytic vacuole membrane 0.00298632016026494 383 83 8 0.0963855421686747 0.02088772845953
GO:CC GO:0030863 cortical cytoskeleton 0.00418145633780001 107 61 4 0.0655737704918033 0.0373831775700935
GO:CC GO:0005938 cell cortex 0.00436666287989675 311 39 5 0.128205128205128 0.0160771704180064
GO:CC GO:0101002 ficolin-1-rich granule 0.00497169184336311 184 38 4 0.105263157894737 0.0217391304347826
GO:CC GO:0031253 cell projection membrane 0.00518765496985501 343 129 9 0.0697674418604651 0.0262390670553936
GO:CC GO:0030864 cortical actin cytoskeleton 0.00518765496985501 79 39 3 0.0769230769230769 0.0379746835443038
GO:CC GO:0030139 endocytic vesicle 0.00518765496985501 306 114 8 0.0701754385964912 0.0261437908496732
GO:CC GO:0005788 endoplasmic reticulum lumen 0.00518765496985501 307 115 8 0.0695652173913043 0.0260586319218241
GO:CC GO:0070820 tertiary granule 0.00555684300000994 163 80 5 0.0625 0.0306748466257669
GO:CC GO:0005774 vacuolar membrane 0.00594571939724668 441 83 8 0.0963855421686747 0.018140589569161
GO:CC GO:0005773 vacuole 0.0066357129397278 810 83 11 0.132530120481928 0.0135802469135802
GO:CC GO:0045177 apical part of cell 0.00818802618836724 431 51 6 0.117647058823529 0.0139211136890951
GO:CC GO:0016324 apical plasma membrane 0.00818802618836724 361 24 4 0.166666666666667 0.0110803324099723
GO:CC GO:0005737 cytoplasm 0.00872270232159237 11911 138 104 0.753623188405797 0.00873142473343968
GO:CC GO:0010008 endosome membrane 0.00882284776210915 505 138 11 0.0797101449275362 0.0217821782178218
GO:CC GO:0031256 leading edge membrane 0.00927949478802538 175 129 6 0.0465116279069767 0.0342857142857143
GO:CC GO:0005901 caveola 0.00997855322272561 83 110 4 0.0363636363636364 0.0481927710843374
GO:CC GO:0045335 phagocytic vesicle 0.0101217877447126 137 114 5 0.043859649122807 0.0364963503649635
GO:CC GO:1904813 ficolin-1-rich granule lumen 0.0135396724448802 124 38 3 0.0789473684210526 0.0241935483870968
GO:CC GO:0031226 intrinsic component of plasma membrane 0.0139729624865326 1726 80 16 0.2 0.00926998841251448
GO:CC GO:0016323 basolateral plasma membrane 0.0155701907384216 222 23 3 0.130434782608696 0.0135135135135135
GO:CC GO:0031252 cell leading edge 0.015622144923323 422 129 9 0.0697674418604651 0.0213270142180095
GO:CC GO:0015629 actin cytoskeleton 0.015660235073478 513 129 10 0.0775193798449612 0.0194931773879142
GO:CC GO:0031984 organelle subcompartment 0.015660235073478 1773 140 24 0.171428571428571 0.0135363790186125
GO:CC GO:0034774 secretory granule lumen 0.0165575984606146 320 58 5 0.0862068965517241 0.015625
GO:CC GO:0031983 vesicle lumen 0.0168310885412186 326 58 5 0.0862068965517241 0.0153374233128834
GO:CC GO:0009925 basal plasma membrane 0.0168310885412186 247 23 3 0.130434782608696 0.0121457489878543
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.0168310885412186 324 58 5 0.0862068965517241 0.0154320987654321
GO:CC GO:0045121 membrane raft 0.0168310885412186 335 110 7 0.0636363636363636 0.0208955223880597
GO:CC GO:0098857 membrane microdomain 0.0168310885412186 335 110 7 0.0636363636363636 0.0208955223880597
GO:CC GO:0005887 integral component of plasma membrane 0.0168310885412186 1645 80 15 0.1875 0.00911854103343465
GO:CC GO:0070821 tertiary granule membrane 0.0171080610820172 72 80 3 0.0375 0.0416666666666667
GO:CC GO:0045178 basal part of cell 0.01854672265533 265 23 3 0.130434782608696 0.0113207547169811
GO:CC GO:0055037 recycling endosome 0.0193638293516934 188 106 5 0.0471698113207547 0.0265957446808511
GO:CC GO:0032587 ruffle membrane 0.0195383285151883 96 129 4 0.0310077519379845 0.0416666666666667
GO:CC GO:0048471 perinuclear region of cytoplasm 0.0202143514875875 735 129 12 0.0930232558139535 0.0163265306122449
GO:CC GO:0044853 plasma membrane raft 0.0212455551172507 116 110 4 0.0363636363636364 0.0344827586206897
GO:CC GO:0030135 coated vesicle 0.0233297644249515 295 23 3 0.130434782608696 0.0101694915254237
GO:CC GO:0030175 filopodium 0.0264867027350939 107 129 4 0.0310077519379845 0.0373831775700935
GO:CC GO:0005769 early endosome 0.0266069391907753 378 138 8 0.0579710144927536 0.0211640211640212
GO:CC GO:0016528 sarcoplasm 0.026742078288447 79 93 3 0.032258064516129 0.0379746835443038
GO:CC GO:0005856 cytoskeleton 0.026742078288447 2332 129 26 0.201550387596899 0.0111492281303602
GO:CC GO:0001726 ruffle 0.0274277986498185 179 129 5 0.0387596899224806 0.0279329608938547
GO:CC GO:0016020 membrane 0.0311429236467361 9838 140 87 0.621428571428571 0.00884326082537101
GO:CC GO:0055038 recycling endosome membrane 0.0325336406229123 84 99 3 0.0303030303030303 0.0357142857142857
GO:CC GO:0043235 receptor complex 0.0329920745229238 522 31 4 0.129032258064516 0.00766283524904215
GO:CC GO:0042995 cell projection 0.0425026805457 2330 129 25 0.193798449612403 0.0107296137339056
GO:CC GO:0072562 blood microparticle 0.0429290053476999 140 125 4 0.032 0.0285714285714286
GO:CC GO:0005911 cell-cell junction 0.0441061960040654 494 122 8 0.0655737704918033 0.0161943319838057
GO:CC GO:0043227 membrane-bounded organelle 0.0449075900842149 12858 59 48 0.813559322033898 0.00373308446103593
GO:CC GO:0005770 late endosome 0.0453310286702046 275 138 6 0.0434782608695652 0.0218181818181818
GO:CC GO:0005791 rough endoplasmic reticulum 0.0464534732643811 86 118 3 0.0254237288135593 0.0348837209302326
GO:CC GO:0031224 intrinsic component of membrane 0.0464960782908598 5868 96 40 0.416666666666667 0.00681663258350375
GO:CC GO:0098858 actin-based cell projection 0.0477351704955603 220 129 5 0.0387596899224806 0.0227272727272727
GO:CC GO:0005789 endoplasmic reticulum membrane 0.0487228407805124 1117 140 15 0.107142857142857 0.0134288272157565
GO:CC GO:0016021 integral component of membrane 0.0487228407805124 5711 96 39 0.40625 0.00682892663281387
GO:CC GO:0098827 endoplasmic reticulum subcompartment 0.0497017398996197 1122 140 15 0.107142857142857 0.0133689839572193
GO:MF GO:0005518 collagen binding 2.14781628740326e-07 70 25 6 0.24 0.0857142857142857
GO:MF GO:0044877 protein-containing complex binding 0.000112202057899661 1287 26 11 0.423076923076923 0.00854700854700855
GO:MF GO:0008237 metallopeptidase activity 0.000112202057899661 188 97 9 0.0927835051546392 0.0478723404255319
GO:MF GO:0004222 metalloendopeptidase activity 0.000128886571735772 108 90 7 0.0777777777777778 0.0648148148148148
GO:MF GO:0004175 endopeptidase activity 0.000190664695741309 450 90 12 0.133333333333333 0.0266666666666667
GO:MF GO:0019003 GDP binding 0.00118411727040031 75 77 5 0.0649350649350649 0.0666666666666667
GO:MF GO:0008233 peptidase activity 0.00209167663557733 646 97 13 0.134020618556701 0.0201238390092879
GO:MF GO:0140375 immune receptor activity 0.0139395540189383 133 80 5 0.0625 0.037593984962406
GO:MF GO:0016491 oxidoreductase activity 0.0163169019302175 771 132 15 0.113636363636364 0.0194552529182879
GO:MF GO:0019899 enzyme binding 0.0163169019302175 2074 129 28 0.217054263565891 0.0135004821600771
GO:MF GO:0020037 heme binding 0.0178557337872422 144 132 6 0.0454545454545455 0.0416666666666667
GO:MF GO:0019838 growth factor binding 0.0178557337872422 138 135 6 0.0444444444444444 0.0434782608695652
GO:MF GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 0.021806660923258 26 130 3 0.0230769230769231 0.115384615384615
GO:MF GO:0046906 tetrapyrrole binding 0.021806660923258 154 132 6 0.0454545454545455 0.038961038961039
GO:MF GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 0.0223341344453544 27 130 3 0.0230769230769231 0.111111111111111
GO:MF GO:0019955 cytokine binding 0.0223753800373802 138 60 4 0.0666666666666667 0.0289855072463768
GO:MF GO:0050840 extracellular matrix binding 0.0223753800373802 56 64 3 0.046875 0.0535714285714286
GO:MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 0.0248818110326938 167 132 6 0.0454545454545455 0.0359281437125748
GO:MF GO:0050839 cell adhesion molecule binding 0.024962174517349 546 129 11 0.0852713178294574 0.0201465201465201
GO:MF GO:0042802 identical protein binding 0.024962174517349 2067 101 22 0.217821782178218 0.0106434446057088
GO:MF GO:0004180 carboxypeptidase activity 0.024962174517349 43 97 3 0.0309278350515464 0.0697674418604651
GO:MF GO:0005201 extracellular matrix structural constituent 0.024962174517349 171 25 3 0.12 0.0175438596491228
GO:MF GO:0005126 cytokine receptor binding 0.024962174517349 275 113 7 0.0619469026548673 0.0254545454545455
GO:MF GO:0008238 exopeptidase activity 0.024962174517349 95 97 4 0.0412371134020619 0.0421052631578947
GO:MF GO:0008270 zinc ion binding 0.0255661055029042 833 6 3 0.5 0.00360144057623049
GO:MF GO:0046914 transition metal ion binding 0.0276723699885704 1111 132 17 0.128787878787879 0.0153015301530153
GO:MF GO:0017022 myosin binding 0.0276723699885704 72 65 3 0.0461538461538462 0.0416666666666667
GO:MF GO:0003725 double-stranded RNA binding 0.0276723699885704 77 133 4 0.0300751879699248 0.051948051948052
GO:MF GO:0005198 structural molecule activity 0.0276723699885704 698 25 5 0.2 0.00716332378223496
GO:MF GO:0060089 molecular transducer activity 0.0328396145665504 1458 40 9 0.225 0.00617283950617284
GO:MF GO:0038023 signaling receptor activity 0.0328396145665504 1458 40 9 0.225 0.00617283950617284
GO:MF GO:0048020 CCR chemokine receptor binding 0.0328396145665504 48 113 3 0.0265486725663717 0.0625
GO:MF GO:0009055 electron transfer activity 0.0340031815647282 148 127 5 0.0393700787401575 0.0337837837837838
GO:MF GO:0005178 integrin binding 0.0347178977505061 147 129 5 0.0387596899224806 0.0340136054421769
GO:MF GO:0003824 catalytic activity 0.0350001564225922 5896 139 59 0.424460431654676 0.0100067842605156
GO:MF GO:0005102 signaling receptor binding 0.0350001564225922 1672 129 21 0.162790697674419 0.0125598086124402
GO:MF GO:0003779 actin binding 0.0350001564225922 448 129 9 0.0697674418604651 0.0200892857142857
GO:MF GO:0051213 dioxygenase activity 0.0350001564225922 96 130 4 0.0307692307692308 0.0416666666666667
GO:MF GO:0005506 iron ion binding 0.0350001564225922 155 132 5 0.0378787878787879 0.032258064516129
GO:MF GO:0004896 cytokine receptor activity 0.0350001564225922 99 60 3 0.05 0.0303030303030303
GO:MF GO:0004714 transmembrane receptor protein tyrosine kinase activity 0.0350001564225922 63 103 3 0.029126213592233 0.0476190476190476
GO:MF GO:0140096 catalytic activity, acting on a protein 0.0350001564225922 2332 115 25 0.217391304347826 0.0107204116638079
GO:MF GO:0008235 metalloexopeptidase activity 0.0350001564225922 63 97 3 0.0309278350515464 0.0476190476190476
GO:MF GO:0016787 hydrolase activity 0.0358308394657615 2615 90 22 0.244444444444444 0.00841300191204589
GO:MF GO:0008092 cytoskeletal protein binding 0.0440455572542553 996 129 14 0.108527131782946 0.0140562248995984
GO:MF GO:0008236 serine-type peptidase activity 0.0450381929704018 189 81 4 0.0493827160493827 0.0211640211640212
GO:MF GO:0015078 proton transmembrane transporter activity 0.0455824928665248 125 123 4 0.032520325203252 0.032
GO:MF GO:0017171 serine hydrolase activity 0.046867561191169 193 81 4 0.0493827160493827 0.0207253886010363
GO:MF GO:0004713 protein tyrosine kinase activity 0.0477544298386984 144 110 4 0.0363636363636364 0.0277777777777778
GO:MF GO:0019199 transmembrane receptor protein kinase activity 0.0477544298386984 82 103 3 0.029126213592233 0.0365853658536585
HP HP:0003741 Congenital muscular dystrophy 0.0488266803124468 20 25 3 0.12 0.15
HP HP:0045039 Osteolysis involving bones of the upper limbs 0.0488266803124468 21 24 3 0.125 0.142857142857143
KEGG KEGG:04216 Ferroptosis 0.00631422545775177 41 74 5 0.0675675675675676 0.121951219512195
MIRNA MIRNA:hsa-miR-942-3p hsa-miR-942-3p 0.0442003683966007 67 79 5 0.0632911392405063 0.0746268656716418
REAC REAC:R-HSA-1442490 Collagen degradation 1.36337673727773e-06 64 90 9 0.1 0.140625
REAC REAC:R-HSA-1474244 Extracellular matrix organization 8.44375057547237e-05 298 26 8 0.307692307692308 0.0268456375838926
REAC REAC:R-HSA-1474228 Degradation of the extracellular matrix 0.000107222157122683 140 25 6 0.24 0.0428571428571429
REAC REAC:R-HSA-1592389 Activation of Matrix Metalloproteinases 0.000904060620248174 33 90 5 0.0555555555555556 0.151515151515152
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.00952210842849934 446 129 16 0.124031007751938 0.0358744394618834
REAC REAC:R-HSA-6798695 Neutrophil degranulation 0.0107748677428155 474 88 13 0.147727272727273 0.0274261603375527
REAC REAC:R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 0.0125462513825751 110 81 6 0.0740740740740741 0.0545454545454545
REAC REAC:R-HSA-186797 Signaling by PDGF 0.013483273179704 54 110 5 0.0454545454545455 0.0925925925925926
REAC REAC:R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 0.0139964521846735 60 25 3 0.12 0.05
REAC REAC:R-HSA-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 0.0139964521846735 14 110 3 0.0272727272727273 0.214285714285714
REAC REAC:R-HSA-2022377 Metabolism of Angiotensinogen to Angiotensins 0.0139964521846735 18 78 3 0.0384615384615385 0.166666666666667
REAC REAC:R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 0.0139964521846735 485 82 12 0.146341463414634 0.0247422680412371
REAC REAC:R-HSA-372708 p130Cas linkage to MAPK signaling for integrins 0.014882573857767 15 110 3 0.0272727272727273 0.2
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 0.0173546691687888 842 81 16 0.197530864197531 0.0190023752969121
REAC REAC:R-HSA-3000178 ECM proteoglycans 0.0200197690789008 75 25 3 0.12 0.04
REAC REAC:R-HSA-8875878 MET promotes cell motility 0.0200197690789008 40 110 4 0.0363636363636364 0.1
REAC REAC:R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 0.0211216147183009 36 129 4 0.0310077519379845 0.111111111111111
REAC REAC:R-HSA-216083 Integrin cell surface interactions 0.0240255547238141 84 26 3 0.115384615384615 0.0357142857142857
REAC REAC:R-HSA-1474290 Collagen formation 0.0241293088770791 89 25 3 0.12 0.0337078651685393
REAC REAC:R-HSA-375165 NCAM signaling for neurite out-growth 0.0248382070478554 59 39 3 0.0769230769230769 0.0508474576271186
REAC REAC:R-HSA-6802957 Oncogenic MAPK signaling 0.0284134764993309 82 110 5 0.0454545454545455 0.0609756097560976
REAC REAC:R-HSA-9020591 Interleukin-12 signaling 0.035710715985489 45 129 4 0.0310077519379845 0.0888888888888889
REAC REAC:R-HSA-354192 Integrin signaling 0.0359219458158835 26 110 3 0.0272727272727273 0.115384615384615
REAC REAC:R-HSA-917937 Iron uptake and transport 0.0359219458158835 57 50 3 0.06 0.0526315789473684
REAC REAC:R-HSA-373755 Semaphorin interactions 0.0381470739263917 64 46 3 0.0652173913043478 0.046875
REAC REAC:R-HSA-6783783 Interleukin-10 signaling 0.0435034346035314 45 70 3 0.0428571428571429 0.0666666666666667
TF TF:M01209 Factor: GAF; motif: CRNATTCCYNK 0.0044692157819461 1434 139 28 0.201438848920863 0.0195258019525802
WP WP:WP129 Matrix Metalloproteinases 0.000298514869463884 30 6 3 0.5 0.1
WP WP:WP3 Phytochemical activity on NRF2 transcriptional activation 0.00141590938977442 15 74 4 0.0540540540540541 0.266666666666667
WP WP:WP4357 NRF2-ARE regulation 0.0014382666924883 23 110 5 0.0454545454545455 0.217391304347826
WP WP:WP4313 Ferroptosis 0.00262131354945148 40 74 5 0.0675675675675676 0.125
WP WP:WP4754 IL-18 signaling pathway 0.0141820970640424 279 10 4 0.4 0.014336917562724
WP WP:WP4462 Platelet-mediated interactions with vascular and circulating cells 0.0182460315593331 17 73 3 0.0410958904109589 0.176470588235294
WP WP:WP2884 NRF2 pathway 0.0182460315593331 145 75 7 0.0933333333333333 0.0482758620689655
WP WP:WP3529 Zinc homeostasis 0.0294514642908284 37 41 3 0.0731707317073171 0.0810810810810811
WP WP:WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling 0.0336065931200998 23 74 3 0.0405405405405405 0.130434782608696
WP WP:WP408 Oxidative Stress 0.0483766346528495 34 127 4 0.031496062992126 0.117647058823529

pM02 transcription factor target enrichment of top program genes

TF enrichment of pM02
TFs corrosponding to activation of pM02. (Left) pearson correlation of TF expression and gene expression program activatity in Myeloid cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.