pTNI17 program activity among T/NK/ILC cells

Activation of pTNI17
pTNI17 gene program activation in T/NK/ILC cells.
Gene program activation of pTNI17 by different cell subtypes
pTNI17 gene program activation among cells of different subtypes (T/NK/ILC cells).

pTNI17 top program genes

Top genes of pTNI17 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pTNI17 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pTNI17
pTNI17 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:306 Ribosome, cytoplasmic 4.69642819029289e-14 80 27 13 0.481481481481481 0.1625
CORUM CORUM:305 40S ribosomal subunit, cytoplasmic 5.69643798699423e-09 33 22 7 0.318181818181818 0.212121212121212
CORUM CORUM:338 40S ribosomal subunit, cytoplasmic 1.48067312742984e-07 31 22 6 0.272727272727273 0.193548387096774
CORUM CORUM:3055 Nop56p-associated pre-rRNA complex 2.76165815505055e-06 104 27 8 0.296296296296296 0.0769230769230769
CORUM CORUM:308 60S ribosomal subunit, cytoplasmic 3.83783995559199e-06 47 27 6 0.222222222222222 0.127659574468085
CORUM CORUM:5380 TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) 0.00303574792932504 25 27 3 0.111111111111111 0.12
GO:BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane 2.86354016916642e-20 96 27 13 0.481481481481481 0.135416666666667
GO:BP GO:0006613 cotranslational protein targeting to membrane 3.30338920498054e-20 102 27 13 0.481481481481481 0.127450980392157
GO:BP GO:0045047 protein targeting to ER 8.96856282137237e-20 113 27 13 0.481481481481481 0.115044247787611
GO:BP GO:0072599 establishment of protein localization to endoplasmic reticulum 1.0813955828167e-19 117 27 13 0.481481481481481 0.111111111111111
GO:BP GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 1.7089597458453e-19 123 27 13 0.481481481481481 0.105691056910569
GO:BP GO:0070972 protein localization to endoplasmic reticulum 1.44695108709739e-18 146 27 13 0.481481481481481 0.089041095890411
GO:BP GO:0019083 viral transcription 2.20326181996154e-17 181 27 13 0.481481481481481 0.0718232044198895
GO:BP GO:0019080 viral gene expression 6.79815375178765e-17 199 27 13 0.481481481481481 0.0653266331658292
GO:BP GO:0006413 translational initiation 6.89978419708077e-17 201 27 13 0.481481481481481 0.0646766169154229
GO:BP GO:0006612 protein targeting to membrane 7.55722549204277e-17 204 27 13 0.481481481481481 0.0637254901960784
GO:BP GO:0000956 nuclear-transcribed mRNA catabolic process 1.29446740659785e-16 214 27 13 0.481481481481481 0.0607476635514019
GO:BP GO:0090150 establishment of protein localization to membrane 1.01025232387988e-14 351 30 14 0.466666666666667 0.0398860398860399
GO:BP GO:0006402 mRNA catabolic process 2.28548959713797e-13 384 27 13 0.481481481481481 0.0338541666666667
GO:BP GO:0006401 RNA catabolic process 7.62127085045794e-13 424 27 13 0.481481481481481 0.0306603773584906
GO:BP GO:0006412 translation 1.06067447162072e-12 764 22 14 0.636363636363636 0.0183246073298429
GO:BP GO:0006605 protein targeting 1.10588443357751e-12 441 27 13 0.481481481481481 0.0294784580498866
GO:BP GO:0043043 peptide biosynthetic process 1.48448835837144e-12 790 22 14 0.636363636363636 0.0177215189873418
GO:BP GO:0043604 amide biosynthetic process 1.35811839118422e-11 932 22 14 0.636363636363636 0.0150214592274678
GO:BP GO:0016032 viral process 1.70653357711004e-11 942 35 17 0.485714285714286 0.0180467091295117
GO:BP GO:0006518 peptide metabolic process 1.70653357711004e-11 955 22 14 0.636363636363636 0.0146596858638743
GO:BP GO:0034655 nucleobase-containing compound catabolic process 2.09700928991563e-11 567 27 13 0.481481481481481 0.0229276895943563
GO:BP GO:0072594 establishment of protein localization to organelle 2.91406619338758e-11 584 27 13 0.481481481481481 0.0222602739726027
GO:BP GO:0072657 protein localization to membrane 3.5160080063767e-11 665 30 14 0.466666666666667 0.0210526315789474
GO:BP GO:0044403 biological process involved in symbiotic interaction 3.65072864110467e-11 1001 35 17 0.485714285714286 0.016983016983017
GO:BP GO:0046700 heterocycle catabolic process 3.7701060629097e-11 602 27 13 0.481481481481481 0.0215946843853821
GO:BP GO:0044270 cellular nitrogen compound catabolic process 4.1110173162968e-11 608 27 13 0.481481481481481 0.0213815789473684
GO:BP GO:0019439 aromatic compound catabolic process 5.39136895724518e-11 623 27 13 0.481481481481481 0.0208667736757624
GO:BP GO:0002181 cytoplasmic translation 8.16258246684957e-11 103 27 8 0.296296296296296 0.0776699029126214
GO:BP GO:1901361 organic cyclic compound catabolic process 8.75467583172089e-11 651 27 13 0.481481481481481 0.0199692780337942
GO:BP GO:1901566 organonitrogen compound biosynthetic process 2.50701369676434e-10 1853 22 16 0.727272727272727 0.00863464651915812
GO:BP GO:0043603 cellular amide metabolic process 3.89038467068313e-10 1241 22 14 0.636363636363636 0.0112812248186946
GO:BP GO:0016071 mRNA metabolic process 2.59307322286568e-09 874 22 12 0.545454545454545 0.0137299771167048
GO:BP GO:0044265 cellular macromolecule catabolic process 7.1187775648677e-09 1231 22 13 0.590909090909091 0.0105605199025183
GO:BP GO:0033365 protein localization to organelle 1.40828734058254e-08 1017 22 12 0.545454545454545 0.0117994100294985
GO:BP GO:0010629 negative regulation of gene expression 5.56291467226057e-08 1460 22 13 0.590909090909091 0.0089041095890411
GO:BP GO:0009057 macromolecule catabolic process 5.78522054509735e-08 1468 22 13 0.590909090909091 0.00885558583106267
GO:BP GO:0006886 intracellular protein transport 7.54540686919652e-08 1186 22 12 0.545454545454545 0.0101180438448567
GO:BP GO:0034613 cellular protein localization 1.46548992351847e-07 2014 16 12 0.75 0.00595829195630586
GO:BP GO:0070727 cellular macromolecule localization 1.51216939914781e-07 2024 16 12 0.75 0.00592885375494071
GO:BP GO:0000028 ribosomal small subunit assembly 2.12278208558879e-07 19 22 4 0.181818181818182 0.210526315789474
GO:BP GO:0051641 cellular localization 3.09930597686763e-07 3541 16 14 0.875 0.00395368539960463
GO:BP GO:0051649 establishment of localization in cell 3.39279912813057e-07 2813 16 13 0.8125 0.00462140063988624
GO:BP GO:0042274 ribosomal small subunit biogenesis 7.8193618121841e-07 74 22 5 0.227272727272727 0.0675675675675676
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 8.22882508448124e-07 2255 35 18 0.514285714285714 0.00798226164079823
GO:BP GO:0006811 ion transport 1.30849988217094e-06 3661 23 17 0.739130434782609 0.00464354001638896
GO:BP GO:0008104 protein localization 4.69833037563117e-06 2770 16 12 0.75 0.00433212996389892
GO:BP GO:0046907 intracellular transport 5.17907706967874e-06 1767 22 12 0.545454545454545 0.0067911714770798
GO:BP GO:0006364 rRNA processing 5.86398172521467e-06 224 22 6 0.272727272727273 0.0267857142857143
GO:BP GO:0016072 rRNA metabolic process 7.31136910402689e-06 234 22 6 0.272727272727273 0.0256410256410256
GO:BP GO:1901575 organic substance catabolic process 7.72712030568039e-06 2267 22 13 0.590909090909091 0.00573445081605646
GO:BP GO:0044248 cellular catabolic process 1.14286381951111e-05 2347 22 13 0.590909090909091 0.00553898593949723
GO:BP GO:0015031 protein transport 1.20252148384695e-05 1929 22 12 0.545454545454545 0.00622083981337481
GO:BP GO:0015833 peptide transport 1.49431966001748e-05 1971 22 12 0.545454545454545 0.0060882800608828
GO:BP GO:0042886 amide transport 1.78815245754197e-05 2007 22 12 0.545454545454545 0.00597907324364723
GO:BP GO:0033036 macromolecule localization 2.02942657769273e-05 3218 16 12 0.75 0.00372902423865755
GO:BP GO:0045184 establishment of protein localization 2.02942657769273e-05 2035 22 12 0.545454545454545 0.0058968058968059
GO:BP GO:0042255 ribosome assembly 2.27619730043184e-05 64 22 4 0.181818181818182 0.0625
GO:BP GO:0042254 ribosome biogenesis 3.03403652111563e-05 307 22 6 0.272727272727273 0.0195439739413681
GO:BP GO:0051651 maintenance of location in cell 5.88435092883245e-05 223 9 4 0.444444444444444 0.0179372197309417
GO:BP GO:0009056 catabolic process 5.97772464589583e-05 2744 22 13 0.590909090909091 0.00473760932944606
GO:BP GO:0071705 nitrogen compound transport 7.55761072380798e-05 2322 22 12 0.545454545454545 0.00516795865633075
GO:BP GO:0034470 ncRNA processing 0.00012362175762386 397 22 6 0.272727272727273 0.0151133501259446
GO:BP GO:0022900 electron transport chain 0.000154068780128542 180 28 5 0.178571428571429 0.0277777777777778
GO:BP GO:0006810 transport 0.000198963219769929 5224 23 17 0.739130434782609 0.0032542113323124
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 0.000212411804277886 3241 16 11 0.6875 0.00339401419315026
GO:BP GO:0022613 ribonucleoprotein complex biogenesis 0.00022641667390663 446 22 6 0.272727272727273 0.0134529147982063
GO:BP GO:0051235 maintenance of location 0.00026650898922716 337 9 4 0.444444444444444 0.0118694362017804
GO:BP GO:0034645 cellular macromolecule biosynthetic process 0.00026650898922716 5051 16 13 0.8125 0.00257374777271827
GO:BP GO:0051234 establishment of localization 0.000275774731087531 5372 23 17 0.739130434782609 0.00316455696202532
GO:BP GO:0009059 macromolecule biosynthetic process 0.000296580982685673 5114 16 13 0.8125 0.00254204145482988
GO:BP GO:0034660 ncRNA metabolic process 0.000367688252143357 493 22 6 0.272727272727273 0.0121703853955375
GO:BP GO:0009892 negative regulation of metabolic process 0.000386031207458327 3479 16 11 0.6875 0.0031618281115263
GO:BP GO:0071702 organic substance transport 0.000394051125614479 2766 16 10 0.625 0.00361532899493854
GO:BP GO:0006820 anion transport 0.000576255042123606 2889 16 10 0.625 0.00346140533056421
GO:BP GO:0048519 negative regulation of biological process 0.00109964340230611 5757 16 13 0.8125 0.00225812054889699
GO:BP GO:0051179 localization 0.00109964340230611 6901 16 14 0.875 0.00202869149398638
GO:BP GO:0022618 ribonucleoprotein complex assembly 0.00137749362995292 197 22 4 0.181818181818182 0.0203045685279188
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 0.00143790590246273 5017 22 15 0.681818181818182 0.00298983456248754
GO:BP GO:1902600 proton transmembrane transport 0.00149438524891042 157 28 4 0.142857142857143 0.0254777070063694
GO:BP GO:0071826 ribonucleoprotein complex subunit organization 0.00152244331656855 204 22 4 0.181818181818182 0.0196078431372549
GO:BP GO:0006396 RNA processing 0.00153852727349212 964 22 7 0.318181818181818 0.00726141078838174
GO:BP GO:0044249 cellular biosynthetic process 0.00214532390632939 6154 16 13 0.8125 0.00211244718882028
GO:BP GO:0044267 cellular protein metabolic process 0.00220714457954366 5229 22 15 0.681818181818182 0.00286861732644865
GO:BP GO:1901576 organic substance biosynthetic process 0.0024359078743414 6248 16 13 0.8125 0.00208066581306018
GO:BP GO:0030036 actin cytoskeleton organization 0.00268758810263154 709 42 8 0.19047619047619 0.0112834978843441
GO:BP GO:0009058 biosynthetic process 0.00281476234153007 6340 16 13 0.8125 0.00205047318611987
GO:BP GO:0016070 RNA metabolic process 0.00307745833815297 4710 22 14 0.636363636363636 0.0029723991507431
GO:BP GO:0042775 mitochondrial ATP synthesis coupled electron transport 0.00505769232987715 99 26 3 0.115384615384615 0.0303030303030303
GO:BP GO:0042773 ATP synthesis coupled electron transport 0.00515808997366515 100 26 3 0.115384615384615 0.03
GO:BP GO:1901564 organonitrogen compound metabolic process 0.00591365378990598 6792 16 13 0.8125 0.00191401648998822
GO:BP GO:0030029 actin filament-based process 0.00605516490833904 808 42 8 0.19047619047619 0.0099009900990099
GO:BP GO:0019538 protein metabolic process 0.00670538942418547 5808 16 12 0.75 0.00206611570247934
GO:BP GO:0022904 respiratory electron transport chain 0.00771128567185335 117 26 3 0.115384615384615 0.0256410256410256
GO:BP GO:0019730 antimicrobial humoral response 0.00786784596286186 145 49 4 0.0816326530612245 0.0275862068965517
GO:BP GO:0060326 cell chemotaxis 0.00794142854947128 310 41 5 0.121951219512195 0.0161290322580645
GO:BP GO:0010468 regulation of gene expression 0.00834444697022119 5196 22 14 0.636363636363636 0.00269438029253272
GO:BP GO:0090304 nucleic acid metabolic process 0.00873928243061232 5226 22 14 0.636363636363636 0.00267891312667432
GO:BP GO:0046034 ATP metabolic process 0.0114801257807159 314 26 4 0.153846153846154 0.0127388535031847
GO:BP GO:0010467 gene expression 0.0115849000012981 6179 16 12 0.75 0.00194206182230134
GO:BP GO:0006414 translational elongation 0.0132301441714443 141 27 3 0.111111111111111 0.0212765957446809
GO:BP GO:0006091 generation of precursor metabolites and energy 0.0138822917849183 538 28 5 0.178571428571429 0.00929368029739777
GO:BP GO:0006119 oxidative phosphorylation 0.0139483674413037 151 26 3 0.115384615384615 0.0198675496688742
GO:BP GO:0070268 cornification 0.0140675428182767 112 35 3 0.0857142857142857 0.0267857142857143
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.0156183883172591 366 42 5 0.119047619047619 0.0136612021857923
GO:BP GO:0034622 cellular protein-containing complex assembly 0.0167798415890129 1107 22 6 0.272727272727273 0.00542005420054201
GO:BP GO:0070925 organelle assembly 0.0168968961790748 895 36 7 0.194444444444444 0.00782122905027933
GO:BP GO:0001892 embryonic placenta development 0.0174294505897929 83 52 3 0.0576923076923077 0.036144578313253
GO:BP GO:0034641 cellular nitrogen compound metabolic process 0.0182043850053439 6563 16 12 0.75 0.00182843211945757
GO:BP GO:0006139 nucleobase-containing compound metabolic process 0.0200303669416319 5746 22 14 0.636363636363636 0.00243647754959972
GO:BP GO:0032970 regulation of actin filament-based process 0.0216459573477727 406 42 5 0.119047619047619 0.0123152709359606
GO:BP GO:0045333 cellular respiration 0.0230582386799156 192 26 3 0.115384615384615 0.015625
GO:BP GO:0046483 heterocycle metabolic process 0.0241412509574416 5904 22 14 0.636363636363636 0.00237127371273713
GO:BP GO:0065003 protein-containing complex assembly 0.0248075246891233 1680 22 7 0.318181818181818 0.00416666666666667
GO:BP GO:0006725 cellular aromatic compound metabolic process 0.0256583284594507 5956 22 14 0.636363636363636 0.00235057085292142
GO:BP GO:1904019 epithelial cell apoptotic process 0.0256583284594507 128 41 3 0.0731707317073171 0.0234375
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 0.0274472009628388 177 31 3 0.0967741935483871 0.0169491525423729
GO:BP GO:0002366 leukocyte activation involved in immune response 0.0302209295421978 717 51 7 0.137254901960784 0.0097629009762901
GO:BP GO:0050921 positive regulation of chemotaxis 0.0302762577162514 141 41 3 0.0731707317073171 0.0212765957446809
GO:BP GO:0002263 cell activation involved in immune response 0.0302762577162514 721 51 7 0.137254901960784 0.00970873786407767
GO:BP GO:1901360 organic cyclic compound metabolic process 0.0336043243135169 6201 22 14 0.636363636363636 0.00225770037090792
GO:BP GO:0007010 cytoskeleton organization 0.0336588445005746 1423 42 9 0.214285714285714 0.00632466619817287
GO:BP GO:0044260 cellular macromolecule metabolic process 0.033994817925593 8390 16 13 0.8125 0.00154946364719905
GO:BP GO:0031424 keratinization 0.0341025131693273 224 55 4 0.0727272727272727 0.0178571428571429
GO:BP GO:0043933 protein-containing complex subunit organization 0.0430726823862208 1963 22 7 0.318181818181818 0.00356597045338767
GO:BP GO:0042742 defense response to bacterium 0.0446856015464631 349 40 4 0.1 0.0114613180515759
GO:BP GO:0051493 regulation of cytoskeleton organization 0.0455083515942502 531 42 5 0.119047619047619 0.00941619585687382
GO:BP GO:0043542 endothelial cell migration 0.0470011793035094 290 49 4 0.0816326530612245 0.0137931034482759
GO:BP GO:0015980 energy derivation by oxidation of organic compounds 0.0476976602961379 289 26 3 0.115384615384615 0.0103806228373702
GO:BP GO:0001890 placenta development 0.0499354980947872 147 52 3 0.0576923076923077 0.0204081632653061
GO:BP GO:0060255 regulation of macromolecule metabolic process 0.0499354980947872 6603 22 14 0.636363636363636 0.00212024837195214
GO:CC GO:0022626 cytosolic ribosome 1.52294688193259e-20 109 27 13 0.481481481481481 0.119266055045872
GO:CC GO:0044391 ribosomal subunit 1.36668571497293e-17 190 27 13 0.481481481481481 0.068421052631579
GO:CC GO:0005840 ribosome 2.6305425556241e-16 245 27 13 0.481481481481481 0.0530612244897959
GO:CC GO:0022627 cytosolic small ribosomal subunit 3.39152438254046e-12 47 22 7 0.318181818181818 0.148936170212766
GO:CC GO:0015935 small ribosomal subunit 8.03166324270043e-11 75 22 7 0.318181818181818 0.0933333333333333
GO:CC GO:1990904 ribonucleoprotein complex 8.03166324270043e-11 688 27 13 0.481481481481481 0.0188953488372093
GO:CC GO:0022625 cytosolic large ribosomal subunit 5.14740488745315e-09 57 27 6 0.222222222222222 0.105263157894737
GO:CC GO:0042788 polysomal ribosome 7.71394701896047e-09 34 21 5 0.238095238095238 0.147058823529412
GO:CC GO:0070062 extracellular exosome 1.57022753573678e-07 2176 58 24 0.413793103448276 0.0110294117647059
GO:CC GO:0005844 polysome 2.37480275678449e-07 72 8 4 0.5 0.0555555555555556
GO:CC GO:0043230 extracellular organelle 2.37480275678449e-07 2263 58 24 0.413793103448276 0.0106053910737958
GO:CC GO:0015934 large ribosomal subunit 2.37480275678449e-07 118 27 6 0.222222222222222 0.0508474576271186
GO:CC GO:1903561 extracellular vesicle 2.37480275678449e-07 2261 58 24 0.413793103448276 0.0106147722246793
GO:CC GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane 3.31561674764689e-07 6 21 3 0.142857142857143 0.5
GO:CC GO:0032991 protein-containing complex 3.95487259095959e-06 5548 31 23 0.741935483870968 0.00414563806777217
GO:CC GO:0070469 respirasome 4.81458115147533e-06 103 28 5 0.178571428571429 0.0485436893203883
GO:CC GO:0098554 cytoplasmic side of endoplasmic reticulum membrane 7.76238152183148e-06 16 21 3 0.142857142857143 0.1875
GO:CC GO:0005829 cytosol 2.27581456751554e-05 5303 22 17 0.772727272727273 0.00320573260418631
GO:CC GO:0030867 rough endoplasmic reticulum membrane 4.14552597552227e-05 29 21 3 0.142857142857143 0.103448275862069
GO:CC GO:0005576 extracellular region 4.660512199494e-05 4567 58 30 0.517241379310345 0.00656886358659952
GO:CC GO:0005615 extracellular space 5.30432798857017e-05 3594 58 26 0.448275862068966 0.00723427935447969
GO:CC GO:0005746 mitochondrial respirasome 7.43943119691489e-05 89 28 4 0.142857142857143 0.0449438202247191
GO:CC GO:0005737 cytoplasm 0.000108625090766455 11911 36 34 0.944444444444444 0.00285450423977836
GO:CC GO:0070069 cytochrome complex 0.000133019705442797 34 28 3 0.107142857142857 0.0882352941176471
GO:CC GO:0031982 vesicle 0.000133019705442797 4055 58 27 0.46551724137931 0.00665844636251541
GO:CC GO:0098800 inner mitochondrial membrane protein complex 0.000452722719367936 146 28 4 0.142857142857143 0.0273972602739726
GO:CC GO:0005743 mitochondrial inner membrane 0.000560883386207873 503 28 6 0.214285714285714 0.0119284294234592
GO:CC GO:0043226 organelle 0.000567503372212496 14008 40 39 0.975 0.0027841233580811
GO:CC GO:0005791 rough endoplasmic reticulum 0.000754181327669254 86 21 3 0.142857142857143 0.0348837209302326
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.000821642686620817 5338 16 12 0.75 0.00224803297115024
GO:CC GO:0043228 non-membrane-bounded organelle 0.000821642686620817 5346 16 12 0.75 0.00224466891133558
GO:CC GO:0043229 intracellular organelle 0.000821642686620817 12491 28 27 0.964285714285714 0.0021615563205508
GO:CC GO:0019866 organelle inner membrane 0.000846330592177239 564 28 6 0.214285714285714 0.0106382978723404
GO:CC GO:0070161 anchoring junction 0.0011802804767606 836 38 8 0.210526315789474 0.00956937799043062
GO:CC GO:0098803 respiratory chain complex 0.00150557234817449 86 28 3 0.107142857142857 0.0348837209302326
GO:CC GO:0005925 focal adhesion 0.00151956448923782 420 27 5 0.185185185185185 0.0119047619047619
GO:CC GO:0030055 cell-substrate junction 0.0016017782198918 427 27 5 0.185185185185185 0.0117096018735363
GO:CC GO:0098798 mitochondrial protein-containing complex 0.00297495474543629 270 28 4 0.142857142857143 0.0148148148148148
GO:CC GO:0031966 mitochondrial membrane 0.00302075441083014 746 28 6 0.214285714285714 0.00804289544235925
GO:CC GO:0005740 mitochondrial envelope 0.00410373431803294 797 28 6 0.214285714285714 0.00752823086574655
GO:CC GO:0043227 membrane-bounded organelle 0.00456274267162652 12858 40 36 0.9 0.00279981334577695
GO:CC GO:0098562 cytoplasmic side of membrane 0.00524514355518581 194 21 3 0.142857142857143 0.0154639175257732
GO:CC GO:0030141 secretory granule 0.0111595295834193 851 54 8 0.148148148148148 0.00940070505287897
GO:CC GO:0034774 secretory granule lumen 0.0176520219980957 320 40 4 0.1 0.0125
GO:CC GO:0031983 vesicle lumen 0.0179218648843802 326 40 4 0.1 0.0122699386503067
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.0179218648843802 324 40 4 0.1 0.0123456790123457
GO:CC GO:0043233 organelle lumen 0.0239177510752994 5565 14 9 0.642857142857143 0.00161725067385445
GO:CC GO:0031974 membrane-enclosed lumen 0.0239177510752994 5565 14 9 0.642857142857143 0.00161725067385445
GO:CC GO:0005882 intermediate filament 0.0249823511156502 218 35 3 0.0857142857142857 0.0137614678899083
GO:CC GO:0005622 intracellular anatomical structure 0.0258372954586202 14790 36 34 0.944444444444444 0.00229885057471264
GO:CC GO:0099503 secretory vesicle 0.0258372954586202 1020 54 8 0.148148148148148 0.00784313725490196
GO:CC GO:0031975 envelope 0.0261384046075041 1237 28 6 0.214285714285714 0.00485044462409054
GO:CC GO:0031967 organelle envelope 0.0261384046075041 1237 28 6 0.214285714285714 0.00485044462409054
GO:CC GO:0012505 endomembrane system 0.0268362022171203 4640 9 6 0.666666666666667 0.00129310344827586
GO:CC GO:0098796 membrane protein complex 0.0274685155545143 1322 35 7 0.2 0.00529500756429652
GO:CC GO:0005783 endoplasmic reticulum 0.0312593145055535 1982 14 5 0.357142857142857 0.00252270433905146
GO:CC GO:0045111 intermediate filament cytoskeleton 0.0330751983120247 259 35 3 0.0857142857142857 0.0115830115830116
GO:CC GO:0098552 side of membrane 0.0419790666219795 619 30 4 0.133333333333333 0.00646203554119548
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.0432960226756554 11296 33 26 0.787878787878788 0.00230169971671388
GO:CC GO:0030054 cell junction 0.0446095685359907 2105 31 8 0.258064516129032 0.00380047505938242
GO:MF GO:0003735 structural constituent of ribosome 6.28501175742349e-18 171 27 13 0.481481481481481 0.0760233918128655
GO:MF GO:0005198 structural molecule activity 4.74071540331666e-11 698 35 15 0.428571428571429 0.0214899713467049
GO:MF GO:0003723 RNA binding 1.89098840815982e-06 1943 22 13 0.590909090909091 0.00669068450849202
GO:MF GO:0009055 electron transfer activity 8.6726182810658e-05 148 28 5 0.178571428571429 0.0337837837837838
GO:MF GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor 0.000167558456935933 27 28 3 0.107142857142857 0.111111111111111
GO:MF GO:0004129 cytochrome-c oxidase activity 0.000167558456935933 27 28 3 0.107142857142857 0.111111111111111
GO:MF GO:0015002 heme-copper terminal oxidase activity 0.000167558456935933 27 28 3 0.107142857142857 0.111111111111111
GO:MF GO:0016675 oxidoreductase activity, acting on a heme group of donors 0.000168729428804156 28 28 3 0.107142857142857 0.107142857142857
GO:MF GO:0003676 nucleic acid binding 0.00345600017942208 4276 22 13 0.590909090909091 0.00304022450888681
GO:MF GO:0016491 oxidoreductase activity 0.00824928855260953 771 28 6 0.214285714285714 0.00778210116731518
GO:MF GO:0015078 proton transmembrane transporter activity 0.00824928855260953 125 28 3 0.107142857142857 0.024
GO:MF GO:0046914 transition metal ion binding 0.0168158883351308 1111 10 4 0.4 0.0036003600360036
GO:MF GO:0004867 serine-type endopeptidase inhibitor activity 0.0209030100334452 98 53 3 0.0566037735849057 0.0306122448979592
GO:MF GO:0003729 mRNA binding 0.0230020062034261 552 11 3 0.272727272727273 0.00543478260869565
HP HP:0020118 Radial artery aplasia 5.50095603244236e-10 22 21 7 0.333333333333333 0.318181818181818
HP HP:0031640 Abnormal radial artery morphology 5.50095603244236e-10 22 21 7 0.333333333333333 0.318181818181818
HP HP:0030270 Elevated red cell adenosine deaminase level 5.50095603244236e-10 22 21 7 0.333333333333333 0.318181818181818
HP HP:0005532 Macrocytic dyserythropoietic anemia 5.91447099454614e-10 23 21 7 0.333333333333333 0.304347826086957
HP HP:0012410 Pure red cell aplasia 7.68902281024139e-10 25 21 7 0.333333333333333 0.28
HP HP:0012133 Erythroid hypoplasia 7.68902281024139e-10 25 21 7 0.333333333333333 0.28
HP HP:0006758 Malignant genitourinary tract tumor 8.9939852092385e-10 26 21 7 0.333333333333333 0.269230769230769
HP HP:0040276 Adenocarcinoma of the colon 1.05950221358664e-09 27 21 7 0.333333333333333 0.259259259259259
HP HP:0030272 Abnormal erythrocyte enzyme level 1.4815663694561e-09 29 21 7 0.333333333333333 0.241379310344828
HP HP:0001227 Abnormality of the thenar eminence 1.4815663694561e-09 29 21 7 0.333333333333333 0.241379310344828
HP HP:0040275 Adenocarcinoma of the large intestine 1.60598175908236e-09 30 21 7 0.333333333333333 0.233333333333333
HP HP:0011904 Persistence of hemoglobin F 1.60598175908236e-09 30 21 7 0.333333333333333 0.233333333333333
HP HP:0001895 Normochromic anemia 1.90957224539638e-09 31 21 7 0.333333333333333 0.225806451612903
HP HP:0001896 Reticulocytopenia 2.67394502652863e-09 33 21 7 0.333333333333333 0.212121212121212
HP HP:0002669 Osteosarcoma 2.67394502652863e-09 33 21 7 0.333333333333333 0.212121212121212
HP HP:0040273 Adenocarcinoma of the intestines 3.92429732260421e-09 35 21 7 0.333333333333333 0.2
HP HP:0009944 Partial duplication of thumb phalanx 5.62380413201507e-09 37 21 7 0.333333333333333 0.189189189189189
HP HP:0012131 Abnormal number of erythroid precursors 6.49283479989447e-09 38 21 7 0.333333333333333 0.184210526315789
HP HP:0005518 Increased mean corpuscular volume 7.10226960149725e-09 39 21 7 0.333333333333333 0.179487179487179
HP HP:0009999 Partial duplication of the phalanx of hand 7.10226960149725e-09 39 21 7 0.333333333333333 0.179487179487179
HP HP:0001790 Nonimmune hydrops fetalis 9.83262820532915e-09 41 21 7 0.333333333333333 0.170731707317073
HP HP:0009777 Absent thumb 1.5866427705199e-08 44 21 7 0.333333333333333 0.159090909090909
HP HP:0025065 Abnormal mean corpuscular volume 3.35551439507008e-08 49 21 7 0.333333333333333 0.142857142857143
HP HP:0001894 Thrombocytosis 3.72890123035756e-08 50 21 7 0.333333333333333 0.14
HP HP:0000912 Sprengel anomaly 4.137833951195e-08 51 21 7 0.333333333333333 0.137254901960784
HP HP:0009942 Duplication of thumb phalanx 5.26811109178254e-08 53 21 7 0.333333333333333 0.132075471698113
HP HP:0011902 Abnormal hemoglobin 5.81250449513385e-08 54 21 7 0.333333333333333 0.12962962962963
HP HP:0001972 Macrocytic anemia 1.20221631541408e-07 60 21 7 0.333333333333333 0.116666666666667
HP HP:0001087 Developmental glaucoma 1.84659070858818e-07 64 21 7 0.333333333333333 0.109375
HP HP:0009380 Aplasia of the fingers 2.08639955923596e-07 66 21 7 0.333333333333333 0.106060606060606
HP HP:0006749 Malignant gastrointestinal tract tumors 2.08639955923596e-07 66 21 7 0.333333333333333 0.106060606060606
HP HP:0002672 Gastrointestinal carcinoma 2.08639955923596e-07 66 21 7 0.333333333333333 0.106060606060606
HP HP:0004808 Acute myeloid leukemia 2.18671701016462e-07 67 21 7 0.333333333333333 0.104477611940299
HP HP:0001199 Triphalangeal thumb 2.18671701016462e-07 67 21 7 0.333333333333333 0.104477611940299
HP HP:0004312 Abnormal reticulocyte morphology 3.54890685966102e-07 72 21 7 0.333333333333333 0.0972222222222222
HP HP:0100273 Neoplasm of the colon 6.08604647888697e-07 78 21 7 0.333333333333333 0.0897435897435897
HP HP:0000085 Horseshoe kidney 8.42743878661043e-07 82 21 7 0.333333333333333 0.0853658536585366
HP HP:0001421 Abnormality of the musculature of the hand 1.45862732076269e-06 89 21 7 0.333333333333333 0.0786516853932584
HP HP:0010622 Neoplasm of the skeletal system 1.93253363867924e-06 93 21 7 0.333333333333333 0.0752688172043011
HP HP:0001789 Hydrops fetalis 2.18560665142955e-06 95 21 7 0.333333333333333 0.0736842105263158
HP HP:0009778 Short thumb 2.64745185280436e-06 98 21 7 0.333333333333333 0.0714285714285714
HP HP:0002863 Myelodysplasia 3.18642503663026e-06 101 21 7 0.333333333333333 0.0693069306930693
HP HP:0002488 Acute leukemia 3.56545471902635e-06 103 21 7 0.333333333333333 0.0679611650485437
HP HP:0000294 Low anterior hairline 3.72551181193146e-06 104 21 7 0.333333333333333 0.0673076923076923
HP HP:0100834 Neoplasm of the large intestine 4.15572418559645e-06 106 21 7 0.333333333333333 0.0660377358490566
HP HP:0000465 Webbed neck 5.58756418506188e-06 111 21 7 0.333333333333333 0.0630630630630631
HP HP:0001680 Coarctation of aorta 6.18397776276119e-06 113 21 7 0.333333333333333 0.0619469026548673
HP HP:0000519 Developmental cataract 1.25065068656589e-05 126 21 7 0.333333333333333 0.0555555555555556
HP HP:0009601 Aplasia/Hypoplasia of the thumb 1.25065068656589e-05 126 21 7 0.333333333333333 0.0555555555555556
HP HP:0008551 Microtia 1.8632999006818e-05 134 21 7 0.333333333333333 0.0522388059701493
HP HP:0000980 Pallor 2.22992891514096e-05 138 21 7 0.333333333333333 0.0507246376811594
HP HP:0008772 Aplasia/Hypoplasia of the external ear 2.29660265916064e-05 139 21 7 0.333333333333333 0.0503597122302158
HP HP:0001909 Leukemia 2.71800626662792e-05 143 14 6 0.428571428571429 0.041958041958042
HP HP:0008771 Aplasia/Hypoplasia of the ear 2.77930413232677e-05 144 14 6 0.428571428571429 0.0416666666666667
HP HP:0000782 Abnormal scapula morphology 3.02536439448369e-05 147 14 6 0.428571428571429 0.0408163265306122
HP HP:0000599 Abnormality of the frontal hairline 3.02536439448369e-05 147 14 6 0.428571428571429 0.0408163265306122
HP HP:0001254 Lethargy 3.42296348385601e-05 189 31 9 0.290322580645161 0.0476190476190476
HP HP:0000185 Cleft soft palate 4.97739362808369e-05 161 14 6 0.428571428571429 0.0372670807453416
HP HP:0100542 Abnormal localization of kidney 5.17122178615067e-05 163 14 6 0.428571428571429 0.0368098159509202
HP HP:0001875 Neutropenia 5.17122178615067e-05 163 14 6 0.428571428571429 0.0368098159509202
HP HP:0010972 Anemia of inadequate production 5.37355778107457e-05 165 14 6 0.428571428571429 0.0363636363636364
HP HP:0100242 Sarcoma 5.37355778107457e-05 165 14 6 0.428571428571429 0.0363636363636364
HP HP:0000104 Renal agenesis 6.51188207064594e-05 171 14 6 0.428571428571429 0.0350877192982456
HP HP:0011991 Abnormal neutrophil count 7.09263517268756e-05 174 14 6 0.428571428571429 0.0344827586206897
HP HP:0009602 Abnormality of thumb phalanx 0.000106070028141577 187 14 6 0.428571428571429 0.0320855614973262
HP HP:0009774 Triangular shaped phalanges of the hand 0.000121680134744579 192 14 6 0.428571428571429 0.03125
HP HP:0410030 Cleft lip 0.000147372382265077 199 14 6 0.428571428571429 0.0301507537688442
HP HP:0001446 Abnormality of the musculature of the upper limbs 0.000158273460668468 202 14 6 0.428571428571429 0.0297029702970297
HP HP:0100736 Abnormal soft palate morphology 0.00017460389544379 206 14 6 0.428571428571429 0.029126213592233
HP HP:0009142 Duplication of bones involving the upper extremities 0.000181821712752351 209 14 6 0.428571428571429 0.0287081339712919
HP HP:0004275 Duplication of hand bones 0.000181821712752351 209 14 6 0.428571428571429 0.0287081339712919
HP HP:0009997 Duplication of phalanx of hand 0.000181821712752351 208 14 6 0.428571428571429 0.0288461538461538
HP HP:0009553 Abnormality of the hairline 0.000199905758560147 213 14 6 0.428571428571429 0.028169014084507
HP HP:0007379 Neoplasm of the genitourinary tract 0.000199905758560147 214 14 6 0.428571428571429 0.0280373831775701
HP HP:0032309 Abnormal granulocyte count 0.000199905758560147 214 14 6 0.428571428571429 0.0280373831775701
HP HP:0001882 Leukopenia 0.000219353865972436 218 14 6 0.428571428571429 0.0275229357798165
HP HP:0001518 Small for gestational age 0.000222251311277704 219 14 6 0.428571428571429 0.0273972602739726
HP HP:0002250 Abnormal large intestine morphology 0.000328104886562057 235 14 6 0.428571428571429 0.025531914893617
HP HP:0004377 Hematological neoplasm 0.000362945280382348 240 14 6 0.428571428571429 0.025
HP HP:0001874 Abnormality of neutrophils 0.000438853627108045 249 14 6 0.428571428571429 0.0240963855421687
HP HP:0011361 Congenital abnormal hair pattern 0.00047442714962678 253 14 6 0.428571428571429 0.0237154150197628
HP HP:0007378 Neoplasm of the gastrointestinal tract 0.000571021166841565 262 14 6 0.428571428571429 0.0229007633587786
HP HP:0007700 Ocular anterior segment dysgenesis 0.000905253791559177 285 14 6 0.428571428571429 0.0210526315789474
HP HP:0010720 Abnormal hair pattern 0.000919480832756135 287 14 6 0.428571428571429 0.0209059233449477
HP HP:0009381 Short finger 0.000919480832756135 287 14 6 0.428571428571429 0.0209059233449477
HP HP:0001911 Abnormal granulocyte morphology 0.000963312806704 290 14 6 0.428571428571429 0.0206896551724138
HP HP:0008678 Renal hypoplasia/aplasia 0.00105569605209247 296 14 6 0.428571428571429 0.0202702702702703
HP HP:0000047 Hypospadias 0.00119779878335724 304 14 6 0.428571428571429 0.0197368421052632
HP HP:0010974 Abnormal myeloid leukocyte morphology 0.00136864556516094 312 14 6 0.428571428571429 0.0192307692307692
HP HP:0100627 Displacement of the urethral meatus 0.00150907923881826 320 14 6 0.428571428571429 0.01875
HP HP:0032076 Abnormal male urethral meatus morphology 0.00150907923881826 320 14 6 0.428571428571429 0.01875
HP HP:0100037 Abnormality of the scalp hair 0.00150907923881826 319 14 6 0.428571428571429 0.0188087774294671
HP HP:0001679 Abnormal aortic morphology 0.00150907923881826 319 14 6 0.428571428571429 0.0188087774294671
HP HP:0001873 Thrombocytopenia 0.0015408281843409 323 14 6 0.428571428571429 0.0185758513931889
HP HP:0000501 Glaucoma 0.0015408281843409 323 14 6 0.428571428571429 0.0185758513931889
HP HP:0011792 Neoplasm by histology 0.0015408281843409 323 14 6 0.428571428571429 0.0185758513931889
HP HP:0006265 Aplasia/Hypoplasia of fingers 0.00155169705274777 324 14 6 0.428571428571429 0.0185185185185185
HP HP:0001965 Abnormal scalp morphology 0.00167184641183347 329 14 6 0.428571428571429 0.0182370820668693
HP HP:0000470 Short neck 0.00168339274737123 330 14 6 0.428571428571429 0.0181818181818182
HP HP:0011873 Abnormal platelet count 0.00199671280256596 341 14 6 0.428571428571429 0.0175953079178886
HP HP:0001172 Abnormal thumb morphology 0.00204204601845955 343 14 6 0.428571428571429 0.0174927113702624
HP HP:0011893 Abnormal leukocyte count 0.00240450124065452 354 14 6 0.428571428571429 0.0169491525423729
HP HP:0001631 Atrial septal defect 0.00265071157522365 361 14 6 0.428571428571429 0.0166204986149584
HP HP:0011994 Abnormal atrial septum morphology 0.002681216653167 363 14 6 0.428571428571429 0.0165289256198347
HP HP:0004372 Reduced consciousness/confusion 0.00277849208354748 366 14 6 0.428571428571429 0.0163934426229508
HP HP:0003319 Abnormality of the cervical spine 0.00287835542635895 369 14 6 0.428571428571429 0.016260162601626
HP HP:0005922 Abnormal hand morphology 0.00298084854998908 372 14 6 0.428571428571429 0.0161290322580645
HP HP:0000795 Abnormality of the urethra 0.00299765454828371 373 14 6 0.428571428571429 0.0160857908847185
HP HP:0001872 Abnormal thrombocyte morphology 0.00301466304616813 374 14 6 0.428571428571429 0.0160427807486631
HP HP:0001629 Ventricular septal defect 0.003496826681881 385 14 6 0.428571428571429 0.0155844155844156
HP HP:0010438 Abnormal ventricular septum morphology 0.00377547652489887 393 14 6 0.428571428571429 0.0152671755725191
HP HP:0005120 Abnormal cardiac atrium morphology 0.00548758839768011 422 14 6 0.428571428571429 0.014218009478673
HP HP:0011004 Abnormal systemic arterial morphology 0.00639748796543111 435 14 6 0.428571428571429 0.0137931034482759
HP HP:0012379 Abnormal enzyme/coenzyme activity 0.00706904687197185 446 14 6 0.428571428571429 0.0134529147982063
HP HP:0009127 Abnormality of the musculature of the limbs 0.00904230920136709 468 14 6 0.428571428571429 0.0128205128205128
HP HP:0005927 Aplasia/hypoplasia involving bones of the hand 0.0095914791366899 474 14 6 0.428571428571429 0.0126582278481013
HP HP:0000286 Epicanthus 0.00972850430295263 476 14 6 0.428571428571429 0.0126050420168067
HP HP:0000969 Edema 0.0109430319700617 489 14 6 0.428571428571429 0.0122699386503067
HP HP:0000518 Cataract 0.0117497821941072 688 14 7 0.5 0.0101744186046512
HP HP:0000431 Wide nasal bridge 0.0117497821941072 497 14 6 0.428571428571429 0.0120724346076459
HP HP:0006496 Aplasia/hypoplasia involving bones of the upper limbs 0.012101946128109 505 14 6 0.428571428571429 0.0118811881188119
HP HP:0005280 Depressed nasal bridge 0.012101946128109 501 14 6 0.428571428571429 0.0119760479041916
HP HP:0001881 Abnormal leukocyte morphology 0.0125557105475714 510 14 6 0.428571428571429 0.0117647058823529
HP HP:0010987 Abnormal cellular immune system morphology 0.0125557105475714 510 14 6 0.428571428571429 0.0117647058823529
HP HP:0000517 Abnormality of the lens 0.0128356480198197 707 14 7 0.5 0.0099009900990099
HP HP:0001903 Anemia 0.0146047308150624 528 14 6 0.428571428571429 0.0113636363636364
HP HP:0032251 Abnormal immune system morphology 0.0150789055086557 532 14 6 0.428571428571429 0.0112781954887218
HP HP:0011927 Short digit 0.0157134006289867 537 14 6 0.428571428571429 0.0111731843575419
HP HP:0001713 Abnormal cardiac ventricle morphology 0.0159076788225903 539 14 6 0.428571428571429 0.0111317254174397
HP HP:0000464 Abnormality of the neck 0.0164109785060912 543 14 6 0.428571428571429 0.0110497237569061
HP HP:0000175 Cleft palate 0.0166112083063766 545 14 6 0.428571428571429 0.0110091743119266
HP HP:0100737 Abnormal hard palate morphology 0.0166566602810108 546 14 6 0.428571428571429 0.010989010989011
HP HP:0011032 Abnormality of fluid regulation 0.0190474698213859 562 14 6 0.428571428571429 0.0106761565836299
HP HP:0001877 Abnormal erythrocyte morphology 0.0204303457037774 572 14 6 0.428571428571429 0.0104895104895105
HP HP:0001671 Abnormal cardiac septum morphology 0.0206621832882019 574 14 6 0.428571428571429 0.0104529616724739
HP HP:0030962 Abnormal morphology of the great vessels 0.0207130659385874 575 14 6 0.428571428571429 0.0104347826086957
HP HP:0000202 Oral cleft 0.0219330060654473 583 14 6 0.428571428571429 0.0102915951972556
HP HP:0045060 Aplasia/hypoplasia involving bones of the extremities 0.0244641438708106 598 14 6 0.428571428571429 0.0100334448160535
HP HP:0005918 Abnormal finger phalanx morphology 0.0301277011431442 631 14 6 0.428571428571429 0.00950871632329636
HP HP:0000218 High palate 0.0301277011431442 631 14 6 0.428571428571429 0.00950871632329636
HP HP:0000036 Abnormal penis morphology 0.0304276197919851 633 14 6 0.428571428571429 0.00947867298578199
HP HP:0000508 Ptosis 0.0316982300596551 639 14 6 0.428571428571429 0.00938967136150235
HP HP:0009815 Aplasia/hypoplasia of the extremities 0.0320729547312201 642 14 6 0.428571428571429 0.00934579439252336
HP HP:0000316 Hypertelorism 0.0362341529850669 663 14 6 0.428571428571429 0.00904977375565611
HP HP:0000377 Abnormality of the pinna 0.0382544160829653 673 14 6 0.428571428571429 0.00891530460624071
HP HP:0000369 Low-set ears 0.0413193934747384 686 14 6 0.428571428571429 0.0087463556851312
HP HP:0000347 Micrognathia 0.0426061191577012 697 14 6 0.428571428571429 0.00860832137733142
HP HP:0009118 Aplasia/Hypoplasia of the mandible 0.0433624679514854 701 14 6 0.428571428571429 0.00855920114122682
HP HP:0010936 Abnormality of the lower urinary tract 0.0433624679514854 701 14 6 0.428571428571429 0.00855920114122682
HP HP:0000549 Abnormal conjugate eye movement 0.0451028333153501 937 14 7 0.5 0.00747065101387407
HP HP:0009116 Aplasia/Hypoplasia involving bones of the skull 0.0455133091583082 711 14 6 0.428571428571429 0.00843881856540084
HP HP:0000357 Abnormal location of ears 0.0482550169741189 721 14 6 0.428571428571429 0.00832177531206657
KEGG KEGG:03010 Ribosome 1.65557501437806e-14 153 27 13 0.481481481481481 0.0849673202614379
KEGG KEGG:05171 Coronavirus disease - COVID-19 1.84481726798761e-12 231 27 13 0.481481481481481 0.0562770562770563
KEGG KEGG:04260 Cardiac muscle contraction 0.00123442970544777 87 26 4 0.153846153846154 0.0459770114942529
KEGG KEGG:00190 Oxidative phosphorylation 0.00520181507033874 133 26 4 0.153846153846154 0.0300751879699248
KEGG KEGG:04932 Non-alcoholic fatty liver disease 0.00611152739077473 150 26 4 0.153846153846154 0.0266666666666667
KEGG KEGG:05415 Diabetic cardiomyopathy 0.0163851218552756 203 26 4 0.153846153846154 0.0197044334975369
KEGG KEGG:04714 Thermogenesis 0.023686889304265 232 26 4 0.153846153846154 0.0172413793103448
KEGG KEGG:05012 Parkinson disease 0.02757121031755 249 26 4 0.153846153846154 0.0160642570281124
KEGG KEGG:05020 Prion disease 0.0347112038454014 273 26 4 0.153846153846154 0.0146520146520147
KEGG KEGG:05016 Huntington disease 0.0471403465273998 306 26 4 0.153846153846154 0.0130718954248366
MIRNA MIRNA:hsa-miR-877-5p hsa-miR-877-5p 0.00341051865501297 233 17 5 0.294117647058824 0.0214592274678112
MIRNA MIRNA:hsa-miR-4461 hsa-miR-4461 0.0323441964610082 74 18 3 0.166666666666667 0.0405405405405405
REAC REAC:R-HSA-72764 Eukaryotic Translation Termination 4.68927556260623e-19 94 27 13 0.481481481481481 0.138297872340426
REAC REAC:R-HSA-156902 Peptide chain elongation 4.68927556260623e-19 90 27 13 0.481481481481481 0.144444444444444
REAC REAC:R-HSA-2408557 Selenocysteine synthesis 4.68927556260623e-19 94 27 13 0.481481481481481 0.138297872340426
REAC REAC:R-HSA-192823 Viral mRNA Translation 4.68927556260623e-19 90 27 13 0.481481481481481 0.144444444444444
REAC REAC:R-HSA-156842 Eukaryotic Translation Elongation 4.68927556260623e-19 94 27 13 0.481481481481481 0.138297872340426
REAC REAC:R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 5.2233263952942e-19 96 27 13 0.481481481481481 0.135416666666667
REAC REAC:R-HSA-72689 Formation of a pool of free 40S subunits 9.01016199732887e-19 102 27 13 0.481481481481481 0.127450980392157
REAC REAC:R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency 9.01016199732887e-19 102 27 13 0.481481481481481 0.127450980392157
REAC REAC:R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 2.65328536251569e-18 113 27 13 0.481481481481481 0.115044247787611
REAC REAC:R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 2.65328536251569e-18 112 27 13 0.481481481481481 0.116071428571429
REAC REAC:R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 2.65328536251569e-18 113 27 13 0.481481481481481 0.115044247787611
REAC REAC:R-HSA-927802 Nonsense-Mediated Decay (NMD) 3.20562141530515e-18 116 27 13 0.481481481481481 0.112068965517241
REAC REAC:R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 3.20562141530515e-18 116 27 13 0.481481481481481 0.112068965517241
REAC REAC:R-HSA-2408522 Selenoamino acid metabolism 3.34455998054289e-18 117 27 13 0.481481481481481 0.111111111111111
REAC REAC:R-HSA-72613 Eukaryotic Translation Initiation 4.12529302788834e-18 120 27 13 0.481481481481481 0.108333333333333
REAC REAC:R-HSA-72737 Cap-dependent Translation Initiation 4.12529302788834e-18 120 27 13 0.481481481481481 0.108333333333333
REAC REAC:R-HSA-9010553 Regulation of expression of SLITs and ROBOs 6.80759422870706e-18 171 27 14 0.518518518518518 0.0818713450292398
REAC REAC:R-HSA-168273 Influenza Viral RNA Transcription and Replication 1.47075194511749e-17 133 27 13 0.481481481481481 0.0977443609022556
REAC REAC:R-HSA-168255 Influenza Infection 8.34625070125997e-17 152 27 13 0.481481481481481 0.0855263157894737
REAC REAC:R-HSA-9711097 Cellular response to starvation 1.22105482484171e-16 157 27 13 0.481481481481481 0.0828025477707006
REAC REAC:R-HSA-376176 Signaling by ROBO receptors 1.65102897406968e-16 217 27 14 0.518518518518518 0.0645161290322581
REAC REAC:R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 8.48469403120845e-16 183 27 13 0.481481481481481 0.0710382513661202
REAC REAC:R-HSA-8868773 rRNA processing in the nucleus and cytosol 1.63797713899167e-15 193 27 13 0.481481481481481 0.0673575129533679
REAC REAC:R-HSA-72312 rRNA processing 3.05217077225328e-15 203 27 13 0.481481481481481 0.0640394088669951
REAC REAC:R-HSA-72766 Translation 3.33755958878137e-13 292 27 13 0.481481481481481 0.0445205479452055
REAC REAC:R-HSA-71291 Metabolism of amino acids and derivatives 6.23978282827128e-12 368 27 13 0.481481481481481 0.0353260869565217
REAC REAC:R-HSA-2262752 Cellular responses to stress 2.73224703167642e-11 546 22 13 0.590909090909091 0.0238095238095238
REAC REAC:R-HSA-422475 Axon guidance 2.82437833960009e-11 549 22 13 0.590909090909091 0.0236794171220401
REAC REAC:R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 3.41044465810553e-11 52 22 7 0.318181818181818 0.134615384615385
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 3.41044465810553e-11 560 22 13 0.590909090909091 0.0232142857142857
REAC REAC:R-HSA-9675108 Nervous system development 4.48562873368655e-11 574 22 13 0.590909090909091 0.0226480836236934
REAC REAC:R-HSA-72702 Ribosomal scanning and start codon recognition 7.83710722298058e-11 59 22 7 0.318181818181818 0.11864406779661
REAC REAC:R-HSA-72649 Translation initiation complex formation 7.83710722298058e-11 59 22 7 0.318181818181818 0.11864406779661
REAC REAC:R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 8.60048657784384e-11 60 22 7 0.318181818181818 0.116666666666667
REAC REAC:R-HSA-5663205 Infectious disease 3.21973426478756e-09 815 22 13 0.590909090909091 0.0159509202453988
REAC REAC:R-HSA-8953854 Metabolism of RNA 4.33629229509059e-09 658 22 12 0.545454545454545 0.0182370820668693
REAC REAC:R-HSA-1266738 Developmental Biology 2.83574134645244e-08 1069 31 16 0.516129032258065 0.0149672591206735
REAC REAC:R-HSA-1643685 Disease 5.06240613877998e-06 1509 22 13 0.590909090909091 0.00861497680583168
REAC REAC:R-HSA-1430728 Metabolism 2.29194348115281e-05 2070 27 16 0.592592592592593 0.00772946859903382
REAC REAC:R-HSA-392499 Metabolism of proteins 6.27567069689781e-05 1961 27 15 0.555555555555556 0.00764915859255482
REAC REAC:R-HSA-611105 Respiratory electron transport 0.00531646583417818 100 26 3 0.115384615384615 0.03
REAC REAC:R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 0.00940473560118607 124 26 3 0.115384615384615 0.0241935483870968
REAC REAC:R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport 0.0227304781564554 174 26 3 0.115384615384615 0.0172413793103448
REAC REAC:R-HSA-6809371 Formation of the cornified envelope 0.0227304781564554 128 35 3 0.0857142857142857 0.0234375
TF TF:M08377_1 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1 0.000105730550738955 5051 33 24 0.727272727272727 0.00475153434963374
TF TF:M11382_1 Factor: ESE-1; motif: NWTRCGGAWGCN; match class: 1 0.000342064830494431 4112 33 21 0.636363636363636 0.00510700389105058
TF TF:M12273_1 Factor: YY1; motif: GGCSGCCATTTTGN; match class: 1 0.000944434044716062 1261 23 10 0.434782608695652 0.00793021411578113
TF TF:M02070_1 Factor: TEL1; motif: CNCGGAANNN; match class: 1 0.000944434044716062 4841 27 19 0.703703703703704 0.00392480892377608
TF TF:M08423_1 Factor: TEF-3:ER81; motif: ACCGGAAATRCC; match class: 1 0.00126351698673374 654 27 8 0.296296296296296 0.0122324159021407
TF TF:M11430 Factor: PEA3; motif: NACCGGAAGTN 0.00126351698673374 10865 36 33 0.916666666666667 0.00303727565577543
TF TF:M03924_1 Factor: YY1; motif: NNCGCCATTNN; match class: 1 0.00126351698673374 3700 21 14 0.666666666666667 0.00378378378378378
TF TF:M07370_1 Factor: YY1; motif: NNNNAARATGGNNNN; match class: 1 0.00126351698673374 1076 23 9 0.391304347826087 0.00836431226765799
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.00126351698673374 10939 28 27 0.964285714285714 0.00246823292805558
TF TF:M11448_1 Factor: Elf-1; motif: NANGCGGAAGTN; match class: 1 0.0018516032758767 2324 27 13 0.481481481481481 0.00559380378657487
TF TF:M08982 Factor: YY1; motif: NAANATGGCGNNN 0.00331393663607748 7125 23 19 0.826086956521739 0.00266666666666667
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.00367465593320898 5745 35 23 0.657142857142857 0.00400348128807659
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.00464130802737719 5133 27 18 0.666666666666667 0.00350672121566335
TF TF:M08637 Factor: TEF-3:Erg; motif: ACCGGAAATRNNNNNCATWCC 0.00464130802737719 4382 23 15 0.652173913043478 0.00342309447740758
TF TF:M08345_1 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN; match class: 1 0.00464130802737719 2198 27 12 0.444444444444444 0.00545950864422202
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.00542155358515516 11728 27 26 0.962962962962963 0.00221691678035471
TF TF:M00793 Factor: YY1; motif: GCCATNTTN 0.00575911813594315 5186 23 16 0.695652173913043 0.00308522946394138
TF TF:M08982_1 Factor: YY1; motif: NAANATGGCGNNN; match class: 1 0.0075470609240517 1662 21 9 0.428571428571429 0.00541516245487365
TF TF:M12275_1 Factor: YY1; motif: NGCCGCCATYTTGN; match class: 1 0.00826342777539729 1600 22 9 0.409090909090909 0.005625
TF TF:M02056_1 Factor: ELF4; motif: NCCGGAARTN; match class: 1 0.00960923737958803 1291 27 9 0.333333333333333 0.0069713400464756
TF TF:M12275 Factor: YY1; motif: NGCCGCCATYTTGN 0.0101577480676044 7043 23 18 0.782608695652174 0.00255572909271617
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.0104815303512667 10107 27 24 0.888888888888889 0.00237459186702286
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.010627802623077 11116 27 25 0.925925925925926 0.00224901043540842
TF TF:M08458_1 Factor: Erm:C/EBPdelta; motif: RSCGGAWRTTGCGYAAY; match class: 1 0.0141229047949381 3168 26 13 0.5 0.00410353535353535
TF TF:M08913_1 Factor: FLI-1; motif: NAYTTCCGGT; match class: 1 0.0145663072642366 3055 27 13 0.481481481481481 0.00425531914893617
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.0145663072642366 4056 27 15 0.555555555555556 0.00369822485207101
TF TF:M08510 Factor: TEF-3:Fli-1; motif: ACCGGAAATGCC 0.0192792039085554 7360 27 20 0.740740740740741 0.00271739130434783
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.0192792039085554 10837 28 25 0.892857142857143 0.0023069115068746
TF TF:M01035 Factor: YY1; motif: NYNKCCATNTT 0.0192792039085554 5924 23 16 0.695652173913043 0.00270087778528022
TF TF:M04849_1 Factor: RelA-p65; motif: AAASTCCC; match class: 1 0.0192792039085554 1170 49 11 0.224489795918367 0.0094017094017094
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.0192792039085554 10765 28 25 0.892857142857143 0.002322340919647
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.0192792039085554 10585 27 24 0.888888888888889 0.00226735947094946
TF TF:M02073_1 Factor: Fli-1; motif: ACCGGAAGYN; match class: 1 0.0192792039085554 1488 27 9 0.333333333333333 0.00604838709677419
TF TF:M10990_1 Factor: lmx1b; motif: NNNNTAATTAN; match class: 1 0.0215535381708681 179 29 4 0.137931034482759 0.0223463687150838
TF TF:M07234 Factor: YY1; motif: CAARATGGCNGC 0.022120318960169 6045 23 16 0.695652173913043 0.00264681555004136
TF TF:M10104 Factor: YY1; motif: CAARATGGCGGC 0.0227603393463755 6071 23 16 0.695652173913043 0.00263548015154011
TF TF:M02044_1 Factor: YY1; motif: GCCGCCATTTTG; match class: 1 0.0236944501706922 1198 21 7 0.333333333333333 0.00584307178631052
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.0236944501706922 7544 27 20 0.740740740740741 0.00265111346765642
TF TF:M03924 Factor: YY1; motif: NNCGCCATTNN 0.0236944501706922 10084 21 19 0.904761904761905 0.00188417294724316
TF TF:M02063_1 Factor: c-ets-1; motif: ACCGGAWGTN; match class: 1 0.0236944501706922 2396 27 11 0.407407407407407 0.00459098497495826
TF TF:M01145 Factor: c-Myc; motif: RACCACGTGCTC 0.0242751068665364 6248 58 32 0.551724137931034 0.00512163892445583
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.0243570377146766 7600 27 20 0.740740740740741 0.00263157894736842
TF TF:M11450 Factor: Elf-1; motif: NANSCGGAAGTR 0.0243570377146766 5601 27 17 0.62962962962963 0.00303517229066238
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.0243570377146766 7600 27 20 0.740740740740741 0.00263157894736842
TF TF:M11438 Factor: SAP-1; motif: NTCGTAAATGCN 0.0244542957149392 5901 26 17 0.653846153846154 0.00288086764955092
TF TF:M00217 Factor: USF; motif: NCACGTGN 0.0251504710551946 4108 26 14 0.538461538461538 0.00340798442064265
TF TF:M11452 Factor: Elf-1; motif: NANGCGGAAGTR 0.0251504710551946 6276 27 18 0.666666666666667 0.00286806883365201
TF TF:M08345 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN 0.0265661843464162 8027 46 31 0.673913043478261 0.00386196586520493
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.0294061435065016 11275 24 22 0.916666666666667 0.00195121951219512
TF TF:M11816 Factor: T3R-beta; motif: NRGGTCAAAGGTCAN 0.0295448500883003 11742 52 43 0.826923076923077 0.00366206779083631
TF TF:M10785 Factor: hoxa9; motif: RTCGTWANNN 0.0295448500883003 5632 23 15 0.652173913043478 0.00266335227272727
TF TF:M07234_1 Factor: YY1; motif: CAARATGGCNGC; match class: 1 0.0295448500883003 1177 23 7 0.304347826086957 0.00594732370433305
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.0295448500883003 6749 28 19 0.678571428571429 0.00281523188620536
TF TF:M08233_1 Factor: ERF:C/EBPdelta; motif: NNCGGAWRTTGCGCAAY; match class: 1 0.0295448500883003 1101 48 10 0.208333333333333 0.00908265213442325
TF TF:M10436_1 Factor: YY1; motif: CAANATGGCGGC; match class: 1 0.0295448500883003 2285 21 9 0.428571428571429 0.00393873085339169
TF TF:M04743 Factor: c-Myc; motif: NSCACGTGGN 0.0295448500883003 4819 26 15 0.576923076923077 0.00311267897904129
TF TF:M03989_1 Factor: FLI1; motif: ACCGGAAATCCGGT; match class: 1 0.0295448500883003 5595 57 29 0.508771929824561 0.00518319928507596
TF TF:M10055_1 Factor: RXR-alpha; motif: NNGNNRNNNARAGGTCANNG; match class: 1 0.0295448500883003 1082 41 9 0.219512195121951 0.00831792975970425
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.0295448500883003 4607 27 15 0.555555555555556 0.0032559149120903
TF TF:M02074_1 Factor: GABPalpha; motif: RCCGGAWRYN; match class: 1 0.0295646429645579 1005 27 7 0.259259259259259 0.00696517412935323
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0301429538197321 4902 31 17 0.548387096774194 0.00346797225622195
TF TF:M08451_1 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA; match class: 1 0.0301429538197321 2584 27 11 0.407407407407407 0.00425696594427245
TF TF:M10849 Factor: Cdx-2; motif: NRTCGTAANNNN 0.0301429538197321 11163 23 21 0.91304347826087 0.00188121472722386
TF TF:M09608 Factor: Erg; motif: NNACCGGAARTSN 0.0301429538197321 8152 48 32 0.666666666666667 0.00392541707556428
TF TF:M01165 Factor: Elk-1; motif: RACCGGAAGTR 0.0314599495237344 7773 48 31 0.645833333333333 0.00398816415798276
TF TF:M02055_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.0314599495237344 2176 27 10 0.37037037037037 0.00459558823529412
TF TF:M01214_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.0314599495237344 2176 27 10 0.37037037037037 0.00459558823529412
TF TF:M11382 Factor: ESE-1; motif: NWTRCGGAWGCN 0.0315704947334711 10339 27 23 0.851851851851852 0.00222458651707128
TF TF:M00059 Factor: YY1; motif: NNNNNCCATNTWNNNWN 0.0321223059930448 4908 10 8 0.8 0.00162999185004075
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.0321223059930448 12550 33 30 0.909090909090909 0.00239043824701195
TF TF:M00799 Factor: Myc; motif: CACGTGS 0.0349816650820757 4988 26 15 0.576923076923077 0.00300721732157177
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.0372890480164081 8056 27 20 0.740740740740741 0.00248262164846077
TF TF:M01752_1 Factor: ERG; motif: ACCGGAART; match class: 1 0.038763693452813 3705 27 13 0.481481481481481 0.00350877192982456
TF TF:M03805_1 Factor: YB-1; motif: CCAMTCNGMR; match class: 1 0.0388875760568786 3680 21 11 0.523809523809524 0.00298913043478261
TF TF:M02062_1 Factor: Erg; motif: ACCGGAAGTN; match class: 1 0.0388875760568786 2718 27 11 0.407407407407407 0.00404709345106696
TF TF:M08767_1 Factor: HES-1; motif: GNCACGTGNC; match class: 1 0.0390115963802399 7709 28 20 0.714285714285714 0.00259437021662991
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.0396885962426221 3233 27 12 0.444444444444444 0.0037117228580266
TF TF:M11381 Factor: ESE-1; motif: SATKGCGGATGCN 0.0396885962426221 15720 33 33 1 0.00209923664122137
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.0396885962426221 4592 31 16 0.516129032258065 0.00348432055749129
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.0396885962426221 4639 28 15 0.535714285714286 0.00323345548609614
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.0399365633406822 3759 27 13 0.481481481481481 0.00345836658685821
TF TF:M11427_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0399365633406822 4606 31 16 0.516129032258065 0.00347372991749891
TF TF:M11381_1 Factor: ESE-1; motif: SATKGCGGATGCN; match class: 1 0.0403313650153972 9745 27 22 0.814814814814815 0.00225756798358132
TF TF:M04696_1 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN; match class: 1 0.0403313650153972 1973 21 8 0.380952380952381 0.00405473897617841
TF TF:M08418 Factor: TEF-3:Elk-1; motif: RMATWCCGGAWGT 0.0403313650153972 11758 32 28 0.875 0.00238135737370301
TF TF:M11270_1 Factor: JunD; motif: NRTGACGTCATS; match class: 1 0.0403539526666843 4298 33 16 0.484848484848485 0.00372266170311773
TF TF:M08637_1 Factor: TEF-3:Erg; motif: ACCGGAAATRNNNNNCATWCC; match class: 1 0.0403753702663231 592 14 4 0.285714285714286 0.00675675675675676
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.0407456337912641 8219 27 20 0.740740740740741 0.0024333860566979
TF TF:M08767 Factor: HES-1; motif: GNCACGTGNC 0.0407456337912641 7813 28 20 0.714285714285714 0.00255983617048509
TF TF:M11058_1 Factor: Hey1; motif: NGCRCGYGYN; match class: 1 0.0419360159962218 10925 28 24 0.857142857142857 0.00219679633867277
TF TF:M03976_1 Factor: ERG; motif: ACCGGAWATCCGGT; match class: 1 0.0419360159962218 7781 21 16 0.761904761904762 0.00205629096517157
TF TF:M11528 Factor: E2F-2; motif: NTTTTGGCGCCAWWWN 0.0419360159962218 10373 55 41 0.745454545454545 0.00395256916996047
TF TF:M04065 Factor: Pax-6; motif: TTTCACGCWTGANTGMNYN 0.0421169900106267 10173 22 19 0.863636363636364 0.00186768898063501
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.0421793184310443 10116 28 23 0.821428571428571 0.00227362593910637
TF TF:M08423 Factor: TEF-3:ER81; motif: ACCGGAAATRCC 0.0421793184310443 3845 27 13 0.481481481481481 0.00338101430429129
TF TF:M02044 Factor: YY1; motif: GCCGCCATTTTG 0.0421793184310443 6102 23 15 0.652173913043478 0.00245821042281219
TF TF:M12350 Factor: zbtb2; motif: NTTTCCGGTAAN 0.0421793184310443 418 20 4 0.2 0.00956937799043062
TF TF:M01035_1 Factor: YY1; motif: NYNKCCATNTT; match class: 1 0.0442048236613782 1112 21 6 0.285714285714286 0.00539568345323741
TF TF:M09812_1 Factor: MYC; motif: NNCCACGTGCNN; match class: 1 0.0442048236613782 5242 26 15 0.576923076923077 0.00286150324303701
TF TF:M11402 Factor: Fli-1; motif: NACCGGAARTN 0.0442048236613782 3885 27 13 0.481481481481481 0.00334620334620335
TF TF:M09606 Factor: nerf; motif: NRRNSCGGAAGNRNNNN 0.0442048236613782 6249 27 17 0.62962962962963 0.00272043526964314
TF TF:M03967 Factor: ELF3; motif: WACCCGGAAGTAN 0.0442048236613782 7610 27 19 0.703703703703704 0.00249671484888305
TF TF:M11617 Factor: Sox-3; motif: SNNACAATRK 0.0442048236613782 3914 10 7 0.7 0.00178845171180378
TF TF:M08224_1 Factor: Elk-1:Pax-1; motif: ACCGGAACTACGCWTSANTG; match class: 1 0.0442048236613782 2748 24 10 0.416666666666667 0.00363901018922853
TF TF:M08246_1 Factor: ER71:C/EBPdelta; motif: NNCGGAWRTTRCGYAAN; match class: 1 0.0445256676368589 2253 24 9 0.375 0.00399467376830892
TF TF:M01894_1 Factor: YY1; motif: CCATNTT; match class: 1 0.0445256676368589 1711 10 5 0.5 0.00292226767971946
TF TF:M02053_1 Factor: ELF1; motif: NCCGGAARTN; match class: 1 0.0445256676368589 1559 27 8 0.296296296296296 0.00513149454778704
TF TF:M11399 Factor: Fli-1; motif: NACCGGAWWTCCGGTY 0.0450854511813596 12977 51 44 0.862745098039216 0.00339061416352007
TF TF:M04696 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN 0.0450907544667428 7819 23 17 0.739130434782609 0.00217419107302724
TF TF:M08390 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA 0.0450907544667428 11072 38 31 0.815789473684211 0.00279985549132948
TF TF:M01154 Factor: c-Myc; motif: KACCACGTGSYY 0.0450907544667428 5313 26 15 0.576923076923077 0.00282326369282891
TF TF:M12273 Factor: YY1; motif: GGCSGCCATTTTGN 0.0454491732889678 6229 23 15 0.652173913043478 0.00240809118638626
TF TF:M08955 Factor: FXR:RXR-ALPHA; motif: NRGGTCANRGGKN 0.0454676532120471 9729 50 36 0.72 0.00370027752081406
TF TF:M11447 Factor: Elf-1; motif: NAMCCGGAAGTN 0.0461057749224733 7703 27 19 0.703703703703704 0.00246657146566273
TF TF:M01154_1 Factor: c-Myc; motif: KACCACGTGSYY; match class: 1 0.0461057749224733 3751 25 12 0.48 0.00319914689416156
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.0461424842556309 14429 22 22 1 0.00152470718691524
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.0461424842556309 7045 27 18 0.666666666666667 0.00255500354861604
TF TF:M00055 Factor: N-Myc; motif: NNCCACGTGNNN 0.0461424842556309 4167 26 13 0.5 0.0031197504199664
TF TF:M11014_1 Factor: ISL2; motif: NCAMTTAN; match class: 1 0.0461424842556309 422 10 3 0.3 0.00710900473933649
TF TF:M04015 Factor: IRF-4; motif: NCGAAACCGAAACYA 0.0461424842556309 2038 9 5 0.555555555555556 0.00245338567222767
TF TF:M10785_1 Factor: hoxa9; motif: RTCGTWANNN; match class: 1 0.0461424842556309 1160 21 6 0.285714285714286 0.00517241379310345
TF TF:M11830 Factor: LRH-1; motif: TGACCTTGRNYCAAGGTCA 0.0461424842556309 7061 52 30 0.576923076923077 0.00424868998725393
TF TF:M11052_1 Factor: Hey2; motif: NNCACGYGNN; match class: 1 0.0461424842556309 9523 28 22 0.785714285714286 0.00231019636669117
TF TF:M08461 Factor: Erm:EVX1; motif: NNCGGAAATKR 0.0470375580504129 3396 31 13 0.419354838709677 0.00382803297997644
TF TF:M09971_1 Factor: GKLF; motif: WGGGYGKGGC; match class: 1 0.0477718760553945 1352 55 11 0.2 0.00813609467455621
TF TF:M09729_1 Factor: LUMAN; motif: CYCAGCYYCY; match class: 1 0.0486483994460143 4645 50 22 0.44 0.00473627556512379
TF TF:M00024 Factor: E2F-1; motif: TWSGCGCGAAAAYKR 0.0486483994460143 8919 12 11 0.916666666666667 0.00123332212131405
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.048851450471564 4024 27 13 0.481481481481481 0.00323061630218688
TF TF:M07140_1 Factor: Kaiso; motif: NTCTCGCGAGANYTN; match class: 1 0.049242855179611 189 22 3 0.136363636363636 0.0158730158730159
WP WP:WP477 Cytoplasmic Ribosomal Proteins 2.92448181568454e-17 90 27 13 0.481481481481481 0.144444444444444
WP WP:WP111 Electron Transport Chain (OXPHOS system in mitochondria) 0.00602576190772873 105 26 4 0.153846153846154 0.0380952380952381
WP WP:WP4396 Nonalcoholic fatty liver disease 0.0122141280060395 159 26 4 0.153846153846154 0.0251572327044025

pTNI17 transcription factor target enrichment of top program genes

TF enrichment of pTNI17
TFs corrosponding to activation of pTNI17. (Left) pearson correlation of TF expression and gene expression program activatity in T/NK/ILC cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.