pEpi40 program activity among Epithelial cells

Activation of pEpi40
pEpi40 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpi40 by different cell subtypes
pEpi40 gene program activation among cells of different subtypes (Epithelial cells).

pEpi40 top program genes

Top genes of pEpi40 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpi40 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpi40
pEpi40 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0140352 export from cell 0.00093892920878968 1418 89 22 0.247191011235955 0.0155148095909732
GO:BP GO:0051674 localization of cell 0.00093892920878968 1828 18 10 0.555555555555556 0.00547045951859956
GO:BP GO:0030334 regulation of cell migration 0.00093892920878968 999 18 8 0.444444444444444 0.00800800800800801
GO:BP GO:0048870 cell motility 0.00093892920878968 1828 18 10 0.555555555555556 0.00547045951859956
GO:BP GO:0046903 secretion 0.00093892920878968 1501 101 24 0.237623762376238 0.0159893404397069
GO:BP GO:0016477 cell migration 0.00093892920878968 1649 18 10 0.555555555555556 0.00606428138265616
GO:BP GO:0002263 cell activation involved in immune response 0.000951544266462939 721 24 8 0.333333333333333 0.0110957004160888
GO:BP GO:0001775 cell activation 0.000952613010147482 1495 26 11 0.423076923076923 0.00735785953177258
GO:BP GO:2000145 regulation of cell motility 0.000983167270424878 1061 18 8 0.444444444444444 0.00754005655042413
GO:BP GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 0.000983167270424878 167 12 4 0.333333333333333 0.0239520958083832
GO:BP GO:0040012 regulation of locomotion 0.00101449256685784 1104 18 8 0.444444444444444 0.0072463768115942
GO:BP GO:0007155 cell adhesion 0.00101449256685784 1492 18 9 0.5 0.00603217158176944
GO:BP GO:0040011 locomotion 0.00101449256685784 2028 18 10 0.555555555555556 0.00493096646942801
GO:BP GO:0044242 cellular lipid catabolic process 0.00101449256685784 232 101 9 0.0891089108910891 0.0387931034482759
GO:BP GO:0045055 regulated exocytosis 0.00101449256685784 785 89 15 0.168539325842697 0.0191082802547771
GO:BP GO:0051270 regulation of cellular component movement 0.00101449256685784 1141 18 8 0.444444444444444 0.007011393514461
GO:BP GO:0022610 biological adhesion 0.00101449256685784 1499 18 9 0.5 0.00600400266844563
GO:BP GO:0032940 secretion by cell 0.0010466896734343 1364 25 10 0.4 0.00733137829912024
GO:BP GO:0051649 establishment of localization in cell 0.00106535918281865 2813 26 14 0.538461538461538 0.00497689299680057
GO:BP GO:0006887 exocytosis 0.00109276291175754 904 89 16 0.179775280898876 0.0176991150442478
GO:BP GO:0016192 vesicle-mediated transport 0.00139004543253744 2180 25 12 0.48 0.0055045871559633
GO:BP GO:0098609 cell-cell adhesion 0.00139004543253744 894 12 6 0.5 0.00671140939597315
GO:BP GO:0030335 positive regulation of cell migration 0.00160699665458443 567 18 6 0.333333333333333 0.0105820105820106
GO:BP GO:2000147 positive regulation of cell motility 0.00195918510139339 591 18 6 0.333333333333333 0.0101522842639594
GO:BP GO:0043299 leukocyte degranulation 0.00198063371934447 535 64 10 0.15625 0.0186915887850467
GO:BP GO:0002275 myeloid cell activation involved in immune response 0.00198063371934447 547 64 10 0.15625 0.0182815356489945
GO:BP GO:0002366 leukocyte activation involved in immune response 0.00198063371934447 717 10 5 0.5 0.00697350069735007
GO:BP GO:0040017 positive regulation of locomotion 0.00198063371934447 606 18 6 0.333333333333333 0.0099009900990099
GO:BP GO:0051272 positive regulation of cellular component movement 0.00198063371934447 604 18 6 0.333333333333333 0.00993377483443709
GO:BP GO:1903034 regulation of response to wounding 0.00198063371934447 169 18 4 0.222222222222222 0.0236686390532544
GO:BP GO:0006928 movement of cell or subcellular component 0.00198063371934447 2311 18 10 0.555555555555556 0.0043271311120727
GO:BP GO:0043086 negative regulation of catalytic activity 0.00201849581263194 851 27 8 0.296296296296296 0.00940070505287897
GO:BP GO:0034109 homotypic cell-cell adhesion 0.00201849581263194 87 12 3 0.25 0.0344827586206897
GO:BP GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 0.00201849581263194 277 12 4 0.333333333333333 0.0144404332129964
GO:BP GO:0002444 myeloid leukocyte mediated immunity 0.00201849581263194 551 64 10 0.15625 0.0181488203266788
GO:BP GO:0043312 neutrophil degranulation 0.00218860065862071 482 47 8 0.170212765957447 0.016597510373444
GO:BP GO:0045765 regulation of angiogenesis 0.00218860065862071 358 10 4 0.4 0.0111731843575419
GO:BP GO:0006469 negative regulation of protein kinase activity 0.00218860065862071 251 64 7 0.109375 0.0278884462151394
GO:BP GO:0051179 localization 0.00218860065862071 6901 27 21 0.777777777777778 0.00304303724097957
GO:BP GO:0009611 response to wounding 0.00218860065862071 674 18 6 0.333333333333333 0.00890207715133531
GO:BP GO:1901342 regulation of vasculature development 0.00218860065862071 364 10 4 0.4 0.010989010989011
GO:BP GO:0002283 neutrophil activation involved in immune response 0.00218860065862071 485 47 8 0.170212765957447 0.0164948453608247
GO:BP GO:0002446 neutrophil mediated immunity 0.00223775322353423 497 24 6 0.25 0.0120724346076459
GO:BP GO:0042119 neutrophil activation 0.00223775322353423 498 24 6 0.25 0.0120481927710843
GO:BP GO:0060548 negative regulation of cell death 0.00223775322353423 1038 18 7 0.388888888888889 0.00674373795761079
GO:BP GO:0050790 regulation of catalytic activity 0.00229597169403982 2545 111 32 0.288288288288288 0.012573673870334
GO:BP GO:0036230 granulocyte activation 0.00231037647232809 504 24 6 0.25 0.0119047619047619
GO:BP GO:0033673 negative regulation of kinase activity 0.00265211170668292 275 27 5 0.185185185185185 0.0181818181818182
GO:BP GO:0045321 leukocyte activation 0.00265211170668292 1332 64 15 0.234375 0.0112612612612613
GO:BP GO:1901215 negative regulation of neuron death 0.00273158589402529 213 18 4 0.222222222222222 0.0187793427230047
GO:BP GO:1903036 positive regulation of response to wounding 0.00274928269541653 74 18 3 0.166666666666667 0.0405405405405405
GO:BP GO:0031400 negative regulation of protein modification process 0.00294398826994428 578 68 10 0.147058823529412 0.0173010380622837
GO:BP GO:0001889 liver development 0.00306519741900517 148 10 3 0.3 0.0202702702702703
GO:BP GO:0050900 leukocyte migration 0.00306519741900517 511 16 5 0.3125 0.00978473581213307
GO:BP GO:0061008 hepaticobiliary system development 0.00316091529718551 151 10 3 0.3 0.0198675496688742
GO:BP GO:0014910 regulation of smooth muscle cell migration 0.00344879321215422 85 18 3 0.166666666666667 0.0352941176470588
GO:BP GO:0021782 glial cell development 0.00344879321215422 122 105 6 0.0571428571428571 0.0491803278688525
GO:BP GO:0065008 regulation of biological quality 0.00345191416619197 4131 90 37 0.411111111111111 0.00895666908738804
GO:BP GO:0051348 negative regulation of transferase activity 0.00365851012150112 310 27 5 0.185185185185185 0.0161290322580645
GO:BP GO:0045766 positive regulation of angiogenesis 0.00368088344997292 187 9 3 0.333333333333333 0.0160427807486631
GO:BP GO:1904018 positive regulation of vasculature development 0.00368088344997292 187 9 3 0.333333333333333 0.0160427807486631
GO:BP GO:0045833 negative regulation of lipid metabolic process 0.0037248203171701 108 15 3 0.2 0.0277777777777778
GO:BP GO:0044319 wound healing, spreading of cells 0.00406317974778006 34 50 3 0.06 0.0882352941176471
GO:BP GO:0002274 myeloid leukocyte activation 0.00406317974778006 667 64 10 0.15625 0.0149925037481259
GO:BP GO:0051641 cellular localization 0.00406317974778006 3541 26 14 0.538461538461538 0.00395368539960463
GO:BP GO:0001819 positive regulation of cytokine production 0.00406317974778006 452 20 5 0.25 0.0110619469026549
GO:BP GO:0001817 regulation of cytokine production 0.00406317974778006 806 26 7 0.269230769230769 0.0086848635235732
GO:BP GO:0014909 smooth muscle cell migration 0.00406317974778006 93 18 3 0.166666666666667 0.032258064516129
GO:BP GO:0090505 epiboly involved in wound healing 0.00406317974778006 34 50 3 0.06 0.0882352941176471
GO:BP GO:0010976 positive regulation of neuron projection development 0.00406317974778006 165 27 4 0.148148148148148 0.0242424242424242
GO:BP GO:0032879 regulation of localization 0.0041307581899964 2872 18 10 0.555555555555556 0.00348189415041783
GO:BP GO:0045936 negative regulation of phosphate metabolic process 0.0041307581899964 543 27 6 0.222222222222222 0.0110497237569061
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.0041307581899964 1082 27 8 0.296296296296296 0.00739371534195933
GO:BP GO:0006810 transport 0.0041307581899964 5224 26 17 0.653846153846154 0.0032542113323124
GO:BP GO:0002695 negative regulation of leukocyte activation 0.0041307581899964 188 10 3 0.3 0.0159574468085106
GO:BP GO:0010563 negative regulation of phosphorus metabolic process 0.0041307581899964 544 27 6 0.222222222222222 0.0110294117647059
GO:BP GO:0090504 epiboly 0.0041307581899964 35 50 3 0.06 0.0857142857142857
GO:BP GO:0045185 maintenance of protein location 0.00421455191055159 98 48 4 0.0833333333333333 0.0408163265306122
GO:BP GO:0008219 cell death 0.00433385562756986 2292 18 9 0.5 0.00392670157068063
GO:BP GO:0001816 cytokine production 0.00444528725364459 844 26 7 0.269230769230769 0.00829383886255924
GO:BP GO:0016042 lipid catabolic process 0.00454397700271204 349 101 9 0.0891089108910891 0.0257879656160458
GO:BP GO:0014812 muscle cell migration 0.00459381073473579 106 18 3 0.166666666666667 0.0283018867924528
GO:BP GO:0048468 cell development 0.00465009818338466 2100 112 27 0.241071428571429 0.0128571428571429
GO:BP GO:0048869 cellular developmental process 0.00493184926472701 4428 112 45 0.401785714285714 0.0101626016260163
GO:BP GO:0061448 connective tissue development 0.0050617565712404 256 110 8 0.0727272727272727 0.03125
GO:BP GO:0007041 lysosomal transport 0.00508071970779558 111 18 3 0.166666666666667 0.027027027027027
GO:BP GO:0051234 establishment of localization 0.00510821874302335 5372 26 17 0.653846153846154 0.00316455696202532
GO:BP GO:0050866 negative regulation of cell activation 0.00514351405542508 211 10 3 0.3 0.014218009478673
GO:BP GO:0044255 cellular lipid metabolic process 0.00520327994296075 1075 107 17 0.158878504672897 0.0158139534883721
GO:BP GO:0043066 negative regulation of apoptotic process 0.00521204760682835 921 18 6 0.333333333333333 0.00651465798045603
GO:BP GO:1902932 positive regulation of alcohol biosynthetic process 0.00521204760682835 25 81 3 0.037037037037037 0.12
GO:BP GO:0002252 immune effector process 0.0052142626736188 1309 24 8 0.333333333333333 0.00611153552330023
GO:BP GO:0051248 negative regulation of protein metabolic process 0.00534055847632169 1151 27 8 0.296296296296296 0.00695047784535187
GO:BP GO:0001933 negative regulation of protein phosphorylation 0.00547311240393853 373 27 5 0.185185185185185 0.0134048257372654
GO:BP GO:0043069 negative regulation of programmed cell death 0.00574050797814784 943 18 6 0.333333333333333 0.0063626723223754
GO:BP GO:0035239 tube morphogenesis 0.00592960813108409 950 18 6 0.333333333333333 0.00631578947368421
GO:BP GO:0030154 cell differentiation 0.00606830840565974 4350 112 44 0.392857142857143 0.0101149425287356
GO:BP GO:0001525 angiogenesis 0.00624232886046863 617 10 4 0.4 0.00648298217179903
GO:BP GO:1901214 regulation of neuron death 0.00644660108927428 323 18 4 0.222222222222222 0.0123839009287926
GO:BP GO:0043549 regulation of kinase activity 0.00652326782110182 921 72 12 0.166666666666667 0.0130293159609121
GO:BP GO:0010594 regulation of endothelial cell migration 0.00674707418930081 244 10 3 0.3 0.0122950819672131
GO:BP GO:0031348 negative regulation of defense response 0.00674707418930081 246 10 3 0.3 0.0121951219512195
GO:BP GO:1902106 negative regulation of leukocyte differentiation 0.00690380904432154 105 100 5 0.05 0.0476190476190476
GO:BP GO:0044092 negative regulation of molecular function 0.00690380904432154 1219 27 8 0.296296296296296 0.00656275635767022
GO:BP GO:0003018 vascular process in circulatory system 0.00690380904432154 256 90 7 0.0777777777777778 0.02734375
GO:BP GO:0002376 immune system process 0.00698681168281763 3278 85 29 0.341176470588235 0.00884685784014643
GO:BP GO:0006897 endocytosis 0.00698681168281763 696 25 6 0.24 0.00862068965517241
GO:BP GO:0019216 regulation of lipid metabolic process 0.00719798091545731 419 15 4 0.266666666666667 0.00954653937947494
GO:BP GO:0042058 regulation of epidermal growth factor receptor signaling pathway 0.00719798091545731 90 27 3 0.111111111111111 0.0333333333333333
GO:BP GO:0045859 regulation of protein kinase activity 0.00739077540194789 809 72 11 0.152777777777778 0.0135970333745365
GO:BP GO:0052547 regulation of peptidase activity 0.00746960676737812 467 37 6 0.162162162162162 0.012847965738758
GO:BP GO:0010001 glial cell differentiation 0.00746960676737812 225 105 7 0.0666666666666667 0.0311111111111111
GO:BP GO:1902105 regulation of leukocyte differentiation 0.00748110473605308 288 59 6 0.101694915254237 0.0208333333333333
GO:BP GO:0042326 negative regulation of phosphorylation 0.00748110473605308 420 27 5 0.185185185185185 0.0119047619047619
GO:BP GO:1903707 negative regulation of hemopoiesis 0.00748110473605308 109 100 5 0.05 0.0458715596330275
GO:BP GO:0042987 amyloid precursor protein catabolic process 0.00748110473605308 71 85 4 0.0470588235294118 0.0563380281690141
GO:BP GO:0018126 protein hydroxylation 0.00761825701160293 28 90 3 0.0333333333333333 0.107142857142857
GO:BP GO:0042110 T cell activation 0.00783048571692277 489 100 10 0.1 0.0204498977505112
GO:BP GO:0070997 neuron death 0.00809904582795146 365 18 4 0.222222222222222 0.010958904109589
GO:BP GO:1901184 regulation of ERBB signaling pathway 0.00809904582795146 97 27 3 0.111111111111111 0.0309278350515464
GO:BP GO:0048514 blood vessel morphogenesis 0.00820117201651206 711 10 4 0.4 0.00562587904360056
GO:BP GO:0043524 negative regulation of neuron apoptotic process 0.00826519221169113 150 18 3 0.166666666666667 0.02
GO:BP GO:0042063 gliogenesis 0.00845140946382458 308 105 8 0.0761904761904762 0.025974025974026
GO:BP GO:0043542 endothelial cell migration 0.00868388931613835 290 10 3 0.3 0.0103448275862069
GO:BP GO:0032502 developmental process 0.00868388931613835 6628 18 14 0.777777777777778 0.00211225105612553
GO:BP GO:0007034 vacuolar transport 0.00868388931613835 154 18 3 0.166666666666667 0.0194805194805195
GO:BP GO:0050435 amyloid-beta metabolic process 0.00952665279560147 68 98 4 0.0408163265306122 0.0588235294117647
GO:BP GO:0002443 leukocyte mediated immunity 0.00954466605605068 877 70 11 0.157142857142857 0.0125427594070696
GO:BP GO:0012501 programmed cell death 0.00957212057489891 2143 14 7 0.5 0.00326644890340644
GO:BP GO:0010632 regulation of epithelial cell migration 0.00966300448364594 306 10 3 0.3 0.00980392156862745
GO:BP GO:0008203 cholesterol metabolic process 0.00976673401789212 154 78 5 0.0641025641025641 0.0324675324675325
GO:BP GO:0030004 cellular monovalent inorganic cation homeostasis 0.00987171658831244 118 58 4 0.0689655172413793 0.0338983050847458
GO:BP GO:0002011 morphogenesis of an epithelial sheet 0.00987171658831244 58 50 3 0.06 0.0517241379310345
GO:BP GO:0009888 tissue development 0.0100893150820256 2107 27 10 0.37037037037037 0.00474608448030375
GO:BP GO:0032507 maintenance of protein location in cell 0.0100893150820256 67 44 3 0.0681818181818182 0.0447761194029851
GO:BP GO:0035295 tube development 0.0105464795011933 1146 18 6 0.333333333333333 0.00523560209424084
GO:BP GO:0051235 maintenance of location 0.010622284897184 337 78 7 0.0897435897435897 0.0207715133531157
GO:BP GO:0001568 blood vessel development 0.010622284897184 792 10 4 0.4 0.00505050505050505
GO:BP GO:0061035 regulation of cartilage development 0.0108543327421379 71 100 4 0.04 0.0563380281690141
GO:BP GO:0006935 chemotaxis 0.0108543327421379 653 81 10 0.123456790123457 0.0153139356814701
GO:BP GO:0043112 receptor metabolic process 0.0108543327421379 174 18 3 0.166666666666667 0.0172413793103448
GO:BP GO:0061036 positive regulation of cartilage development 0.0109508935441683 31 100 3 0.03 0.0967741935483871
GO:BP GO:0042330 taxis 0.0111346275328561 656 81 10 0.123456790123457 0.0152439024390244
GO:BP GO:0051239 regulation of multicellular organismal process 0.0111899616513085 2861 110 31 0.281818181818182 0.0108353722474659
GO:BP GO:0043393 regulation of protein binding 0.0112847099837656 199 64 5 0.078125 0.0251256281407035
GO:BP GO:1902652 secondary alcohol metabolic process 0.0116100182965785 164 78 5 0.0641025641025641 0.0304878048780488
GO:BP GO:0051338 regulation of transferase activity 0.0118240805599547 1035 72 12 0.166666666666667 0.0115942028985507
GO:BP GO:0001944 vasculature development 0.0118737710461299 830 10 4 0.4 0.00481927710843374
GO:BP GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 0.0118737710461299 760 27 6 0.222222222222222 0.00789473684210526
GO:BP GO:0043085 positive regulation of catalytic activity 0.0120272482663576 1418 109 19 0.174311926605505 0.0133991537376587
GO:BP GO:0065009 regulation of molecular function 0.0120273993360266 3221 51 19 0.372549019607843 0.00589878919590189
GO:BP GO:2000026 regulation of multicellular organismal development 0.0120273993360266 1447 107 19 0.177570093457944 0.0131306150656531
GO:BP GO:0003013 circulatory system process 0.0120273993360266 637 100 11 0.11 0.0172684458398744
GO:BP GO:0007173 epidermal growth factor receptor signaling pathway 0.0122222932990821 123 27 3 0.111111111111111 0.024390243902439
GO:BP GO:0006629 lipid metabolic process 0.0123016351834139 1457 39 10 0.256410256410256 0.00686341798215511
GO:BP GO:0016125 sterol metabolic process 0.0124657707996875 171 78 5 0.0641025641025641 0.0292397660818713
GO:BP GO:0048844 artery morphogenesis 0.0124657707996875 77 100 4 0.04 0.051948051948052
GO:BP GO:0010941 regulation of cell death 0.0124657707996875 1720 18 7 0.388888888888889 0.00406976744186047
GO:BP GO:0051336 regulation of hydrolase activity 0.0124657707996875 1321 109 18 0.165137614678899 0.0136260408781226
GO:BP GO:0016486 peptide hormone processing 0.0124657707996875 35 98 3 0.0306122448979592 0.0857142857142857
GO:BP GO:0045851 pH reduction 0.0124893827972701 59 58 3 0.0517241379310345 0.0508474576271186
GO:BP GO:0006915 apoptotic process 0.0124912066653591 1990 12 6 0.5 0.00301507537688442
GO:BP GO:0010631 epithelial cell migration 0.0126574960027868 370 10 3 0.3 0.00810810810810811
GO:BP GO:0044283 small molecule biosynthetic process 0.0126574960027868 704 107 12 0.11214953271028 0.0170454545454545
GO:BP GO:0090132 epithelium migration 0.0126752030990748 373 10 3 0.3 0.00804289544235925
GO:BP GO:0060429 epithelium development 0.0126752030990748 1325 17 6 0.352941176470588 0.00452830188679245
GO:BP GO:0007167 enzyme linked receptor protein signaling pathway 0.0126752030990748 1103 27 7 0.259259259259259 0.00634632819582956
GO:BP GO:0090130 tissue migration 0.0127135880925 379 10 3 0.3 0.0079155672823219
GO:BP GO:0048856 anatomical structure development 0.0127135880925 6106 18 13 0.722222222222222 0.00212905339010809
GO:BP GO:0044093 positive regulation of molecular function 0.0127135880925 1771 51 13 0.254901960784314 0.00734048560135517
GO:BP GO:0140448 signaling receptor ligand precursor processing 0.0127135880925 36 98 3 0.0306122448979592 0.0833333333333333
GO:BP GO:0070268 cornification 0.0127618814249358 112 32 3 0.09375 0.0267857142857143
GO:BP GO:0031099 regeneration 0.0130401237419279 206 18 3 0.166666666666667 0.0145631067961165
GO:BP GO:0071417 cellular response to organonitrogen compound 0.0130401237419279 666 85 10 0.117647058823529 0.015015015015015
GO:BP GO:0033036 macromolecule localization 0.0130401237419279 3218 72 24 0.333333333333333 0.0074580484773151
GO:BP GO:0007417 central nervous system development 0.0130401237419279 1032 9 4 0.444444444444444 0.00387596899224806
GO:BP GO:0042982 amyloid precursor protein metabolic process 0.0130401237419279 96 85 4 0.0470588235294118 0.0416666666666667
GO:BP GO:0022612 gland morphogenesis 0.013175807960137 120 118 5 0.0423728813559322 0.0416666666666667
GO:BP GO:0030258 lipid modification 0.013175807960137 271 107 7 0.0654205607476635 0.025830258302583
GO:BP GO:0032970 regulation of actin filament-based process 0.013175807960137 406 72 7 0.0972222222222222 0.0172413793103448
GO:BP GO:0050678 regulation of epithelial cell proliferation 0.013267914906915 401 10 3 0.3 0.00748129675810474
GO:BP GO:0043523 regulation of neuron apoptotic process 0.0135237706526337 216 18 3 0.166666666666667 0.0138888888888889
GO:BP GO:0030279 negative regulation of ossification 0.0135237706526337 38 100 3 0.03 0.0789473684210526
GO:BP GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 0.0135237706526337 59 64 3 0.046875 0.0508474576271186
GO:BP GO:0032102 negative regulation of response to external stimulus 0.0135237706526337 406 10 3 0.3 0.00738916256157635
GO:BP GO:0006955 immune response 0.0135237706526337 2311 27 10 0.37037037037037 0.0043271311120727
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0135237706526337 2541 51 16 0.313725490196078 0.00629673356946084
GO:BP GO:0042157 lipoprotein metabolic process 0.0135844590604449 136 62 4 0.0645161290322581 0.0294117647058824
GO:BP GO:0051216 cartilage development 0.0139284817714107 196 110 6 0.0545454545454545 0.0306122448979592
GO:BP GO:0006873 cellular ion homeostasis 0.0139821599254109 687 70 9 0.128571428571429 0.0131004366812227
GO:BP GO:0038127 ERBB signaling pathway 0.0140466047220688 145 27 3 0.111111111111111 0.0206896551724138
GO:BP GO:0010810 regulation of cell-substrate adhesion 0.0141886056781122 222 18 3 0.166666666666667 0.0135135135135135
GO:BP GO:1903530 regulation of secretion by cell 0.0141897349372682 588 98 10 0.102040816326531 0.0170068027210884
GO:BP GO:0002683 negative regulation of immune system process 0.0142101230879281 420 10 3 0.3 0.00714285714285714
GO:BP GO:0022008 neurogenesis 0.0142101230879281 1675 112 21 0.1875 0.0125373134328358
GO:BP GO:0060284 regulation of cell development 0.0142101230879281 502 18 4 0.222222222222222 0.00796812749003984
GO:BP GO:0048729 tissue morphogenesis 0.0145722187079163 667 118 12 0.101694915254237 0.0179910044977511
GO:BP GO:0051094 positive regulation of developmental process 0.0146773534913897 1341 18 6 0.333333333333333 0.00447427293064877
GO:BP GO:0032103 positive regulation of response to external stimulus 0.0149269155619417 513 18 4 0.222222222222222 0.00779727095516569
GO:BP GO:0051128 regulation of cellular component organization 0.0152737253813986 2412 107 26 0.242990654205607 0.0107794361525705
GO:BP GO:0048732 gland development 0.0152737253813986 436 10 3 0.3 0.00688073394495413
GO:BP GO:0007162 negative regulation of cell adhesion 0.0153321452818035 304 100 7 0.07 0.0230263157894737
GO:BP GO:0042398 cellular modified amino acid biosynthetic process 0.0157500719039316 46 90 3 0.0333333333333333 0.0652173913043478
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 0.0157500719039316 1202 14 5 0.357142857142857 0.00415973377703827
GO:BP GO:1903779 regulation of cardiac conduction 0.0157500719039316 59 70 3 0.0428571428571429 0.0508474576271186
GO:BP GO:0022407 regulation of cell-cell adhesion 0.0158153605825407 445 10 3 0.3 0.00674157303370787
GO:BP GO:0002009 morphogenesis of an epithelium 0.0158323395580387 560 17 4 0.235294117647059 0.00714285714285714
GO:BP GO:0032092 positive regulation of protein binding 0.0158600478557607 85 49 3 0.0612244897959184 0.0352941176470588
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.0159521666554676 1645 108 20 0.185185185185185 0.0121580547112462
GO:BP GO:0019220 regulation of phosphate metabolic process 0.0159521666554676 1645 108 20 0.185185185185185 0.0121580547112462
GO:BP GO:0019395 fatty acid oxidation 0.0160371382290929 108 39 3 0.0769230769230769 0.0277777777777778
GO:BP GO:0060627 regulation of vesicle-mediated transport 0.0160949186460843 536 18 4 0.222222222222222 0.00746268656716418
GO:BP GO:0051246 regulation of protein metabolic process 0.0161202781372064 2704 92 25 0.271739130434783 0.00924556213017752
GO:BP GO:0007399 nervous system development 0.0163504160100503 2449 112 27 0.241071428571429 0.0110249081257656
GO:BP GO:0050673 epithelial cell proliferation 0.0163504160100503 460 10 3 0.3 0.00652173913043478
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.0164511498676428 1042 10 4 0.4 0.00383877159309021
GO:BP GO:0006950 response to stress 0.0166427676643766 4170 34 16 0.470588235294118 0.00383693045563549
GO:BP GO:0032101 regulation of response to external stimulus 0.0168437586157096 1051 10 4 0.4 0.00380589914367269
GO:BP GO:0051402 neuron apoptotic process 0.0169689145099026 250 18 3 0.166666666666667 0.012
GO:BP GO:0034440 lipid oxidation 0.0170344370473143 113 39 3 0.0769230769230769 0.0265486725663717
GO:BP GO:0048666 neuron development 0.0170933961527392 1149 112 16 0.142857142857143 0.0139251523063534
GO:BP GO:0031346 positive regulation of cell projection organization 0.0170933961527392 359 27 4 0.148148148148148 0.011142061281337
GO:BP GO:1902991 regulation of amyloid precursor protein catabolic process 0.0173709579794742 57 78 3 0.0384615384615385 0.0526315789473684
GO:BP GO:0055067 monovalent inorganic cation homeostasis 0.0174694117863506 165 58 4 0.0689655172413793 0.0242424242424242
GO:BP GO:0051050 positive regulation of transport 0.0174694117863506 923 78 11 0.141025641025641 0.0119176598049837
GO:BP GO:0042592 homeostatic process 0.0175849611877454 1981 18 7 0.388888888888889 0.00353356890459364
GO:BP GO:0071901 negative regulation of protein serine/threonine kinase activity 0.0175849611877454 150 64 4 0.0625 0.0266666666666667
GO:BP GO:1901699 cellular response to nitrogen compound 0.0178653389212429 724 85 10 0.117647058823529 0.0138121546961326
GO:BP GO:0051651 maintenance of location in cell 0.017933450867794 223 44 4 0.0909090909090909 0.0179372197309417
GO:BP GO:0010466 negative regulation of peptidase activity 0.0179791701139115 267 37 4 0.108108108108108 0.0149812734082397
GO:BP GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.0179791701139115 46 100 3 0.03 0.0652173913043478
GO:BP GO:0001667 ameboidal-type cell migration 0.0179920039093236 494 10 3 0.3 0.00607287449392713
GO:BP GO:0045596 negative regulation of cell differentiation 0.0180810287622614 697 15 4 0.266666666666667 0.00573888091822095
GO:BP GO:0009605 response to external stimulus 0.0180825087453117 2944 10 6 0.6 0.00203804347826087
GO:BP GO:0051247 positive regulation of protein metabolic process 0.0180849504233804 1564 108 19 0.175925925925926 0.0121483375959079
GO:BP GO:0007154 cell communication 0.0180849504233804 6829 27 18 0.666666666666667 0.00263581783570069
GO:BP GO:0042981 regulation of apoptotic process 0.0181871218156076 1549 12 5 0.416666666666667 0.00322788896061975
GO:BP GO:0048871 multicellular organismal homeostasis 0.0181871218156076 530 62 7 0.112903225806452 0.0132075471698113
GO:BP GO:0120035 regulation of plasma membrane bounded cell projection organization 0.0187904453322112 638 27 5 0.185185185185185 0.00783699059561128
GO:BP GO:0098771 inorganic ion homeostasis 0.0187904453322112 761 33 6 0.181818181818182 0.00788436268068331
GO:BP GO:0006805 xenobiotic metabolic process 0.018915276383331 122 39 3 0.0769230769230769 0.0245901639344262
GO:BP GO:0030510 regulation of BMP signaling pathway 0.0192640584114468 96 105 4 0.0380952380952381 0.0416666666666667
GO:BP GO:0050878 regulation of body fluid levels 0.0192640584114468 514 10 3 0.3 0.00583657587548638
GO:BP GO:0046890 regulation of lipid biosynthetic process 0.0192640584114468 215 78 5 0.0641025641025641 0.0232558139534884
GO:BP GO:0043067 regulation of programmed cell death 0.0193512329044862 1582 12 5 0.416666666666667 0.00316055625790139
GO:BP GO:0031333 negative regulation of protein-containing complex assembly 0.0194827117461073 147 69 4 0.0579710144927536 0.0272108843537415
GO:BP GO:0006664 glycolipid metabolic process 0.0196301933130118 112 91 4 0.043956043956044 0.0357142857142857
GO:BP GO:0030855 epithelial cell differentiation 0.0196301933130118 798 32 6 0.1875 0.0075187969924812
GO:BP GO:0060840 artery development 0.0196301933130118 102 100 4 0.04 0.0392156862745098
GO:BP GO:0046165 alcohol biosynthetic process 0.0196301933130118 158 107 5 0.0467289719626168 0.0316455696202532
GO:BP GO:0045581 negative regulation of T cell differentiation 0.0196404642405667 49 100 3 0.03 0.0612244897959184
GO:BP GO:1903706 regulation of hemopoiesis 0.0196404642405667 424 59 6 0.101694915254237 0.0141509433962264
GO:BP GO:0031175 neuron projection development 0.0196404642405667 1012 107 14 0.130841121495327 0.0138339920948617
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0196586467892676 470 37 5 0.135135135135135 0.0106382978723404
GO:BP GO:1903509 liposaccharide metabolic process 0.0196586467892676 113 91 4 0.043956043956044 0.0353982300884956
GO:BP GO:0030182 neuron differentiation 0.0196586467892676 1412 112 18 0.160714285714286 0.0127478753541076
GO:BP GO:0071466 cellular response to xenobiotic stimulus 0.0197520929295976 127 39 3 0.0769230769230769 0.0236220472440945
GO:BP GO:0031344 regulation of cell projection organization 0.0197520929295976 656 27 5 0.185185185185185 0.00762195121951219
GO:BP GO:0060326 cell chemotaxis 0.0199063432324536 310 81 6 0.0740740740740741 0.0193548387096774
GO:BP GO:0090181 regulation of cholesterol metabolic process 0.0199063432324536 64 78 3 0.0384615384615385 0.046875
GO:BP GO:0009719 response to endogenous stimulus 0.0199063432324536 1683 110 20 0.181818181818182 0.011883541295306
GO:BP GO:0002521 leukocyte differentiation 0.0199063432324536 550 62 7 0.112903225806452 0.0127272727272727
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.0199063432324536 1455 84 15 0.178571428571429 0.0103092783505155
GO:BP GO:0051046 regulation of secretion 0.0199063432324536 647 98 10 0.102040816326531 0.0154559505409583
GO:BP GO:0034205 amyloid-beta formation 0.0199812545979028 59 85 3 0.0352941176470588 0.0508474576271186
GO:BP GO:0001932 regulation of protein phosphorylation 0.0202773286490994 1240 108 16 0.148148148148148 0.0129032258064516
GO:BP GO:0051049 regulation of transport 0.0202791679726967 1809 89 18 0.202247191011236 0.00995024875621891
GO:BP GO:0032330 regulation of chondrocyte differentiation 0.0206275503868598 51 100 3 0.03 0.0588235294117647
GO:BP GO:0002820 negative regulation of adaptive immune response 0.0206275503868598 51 100 3 0.03 0.0588235294117647
GO:BP GO:0010876 lipid localization 0.0206809985610794 530 101 9 0.0891089108910891 0.0169811320754717
GO:BP GO:0043407 negative regulation of MAP kinase activity 0.0207988856236207 80 64 3 0.046875 0.0375
GO:BP GO:0072359 circulatory system development 0.0208270712542317 1194 10 4 0.4 0.0033500837520938
GO:BP GO:0030162 regulation of proteolysis 0.020895368947701 752 100 11 0.11 0.0146276595744681
GO:BP GO:0048585 negative regulation of response to stimulus 0.0209992687135911 1733 27 8 0.296296296296296 0.00461627236006924
GO:BP GO:0030029 actin filament-based process 0.0209992687135911 808 107 12 0.11214953271028 0.0148514851485149
GO:BP GO:0051222 positive regulation of protein transport 0.0210856984476887 329 78 6 0.0769230769230769 0.0182370820668693
GO:BP GO:0009410 response to xenobiotic stimulus 0.0210856984476887 134 39 3 0.0769230769230769 0.0223880597014925
GO:BP GO:0019229 regulation of vasoconstriction 0.0210856984476887 64 81 3 0.037037037037037 0.046875
GO:BP GO:0050801 ion homeostasis 0.0213432530742522 808 33 6 0.181818181818182 0.00742574257425743
GO:BP GO:0009968 negative regulation of signal transduction 0.021772513665178 1364 27 7 0.259259259259259 0.00513196480938416
GO:BP GO:1901653 cellular response to peptide 0.021772513665178 408 64 6 0.09375 0.0147058823529412
GO:BP GO:0048699 generation of neurons 0.021772513665178 1559 112 19 0.169642857142857 0.0121872995509942
GO:BP GO:0030514 negative regulation of BMP signaling pathway 0.021772513665178 53 100 3 0.03 0.0566037735849057
GO:BP GO:0046649 lymphocyte activation 0.0221446589204881 771 85 10 0.117647058823529 0.012970168612192
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.0225350735288534 366 72 6 0.0833333333333333 0.0163934426229508
GO:BP GO:0023051 regulation of signaling 0.0230695810755026 3578 118 36 0.305084745762712 0.0100614868641699
GO:BP GO:0097435 supramolecular fiber organization 0.0230695810755026 734 90 10 0.111111111111111 0.0136239782016349
GO:BP GO:0030641 regulation of cellular pH 0.0231255313222528 95 58 3 0.0517241379310345 0.0315789473684211
GO:BP GO:0008015 blood circulation 0.0231255313222528 553 100 9 0.09 0.0162748643761302
GO:BP GO:0017157 regulation of exocytosis 0.0231403688313376 207 89 5 0.0561797752808989 0.0241545893719807
GO:BP GO:0062012 regulation of small molecule metabolic process 0.0231403688313376 447 13 3 0.230769230769231 0.00671140939597315
GO:BP GO:0008202 steroid metabolic process 0.0231438770379684 342 78 6 0.0769230769230769 0.0175438596491228
GO:BP GO:0051716 cellular response to stimulus 0.0236973234212552 7781 27 19 0.703703703703704 0.00244184552114124
GO:BP GO:0051223 regulation of protein transport 0.0236973234212552 586 78 8 0.102564102564103 0.0136518771331058
GO:BP GO:0055082 cellular chemical homeostasis 0.0238994573666995 841 33 6 0.181818181818182 0.00713436385255648
GO:BP GO:1904951 positive regulation of establishment of protein localization 0.0238994573666995 345 78 6 0.0769230769230769 0.0173913043478261
GO:BP GO:0043588 skin development 0.0244898296070349 424 14 3 0.214285714285714 0.00707547169811321
GO:BP GO:0045620 negative regulation of lymphocyte differentiation 0.0244898296070349 57 100 3 0.03 0.0526315789473684
GO:BP GO:0002694 regulation of leukocyte activation 0.0244898296070349 610 10 3 0.3 0.00491803278688525
GO:BP GO:0006457 protein folding 0.0246277849091704 225 26 3 0.115384615384615 0.0133333333333333
GO:BP GO:0048469 cell maturation 0.0250737724701782 170 112 5 0.0446428571428571 0.0294117647058824
GO:BP GO:0062013 positive regulation of small molecule metabolic process 0.0250737724701782 145 81 4 0.0493827160493827 0.0275862068965517
GO:BP GO:0009887 animal organ morphogenesis 0.0250737724701782 1073 118 15 0.127118644067797 0.0139794967381174
GO:BP GO:0006898 receptor-mediated endocytosis 0.0250737724701782 333 18 3 0.166666666666667 0.00900900900900901
GO:BP GO:0006820 anion transport 0.0251035161497436 2889 64 19 0.296875 0.006576670128072
GO:BP GO:0090066 regulation of anatomical structure size 0.0254810572472238 518 90 8 0.0888888888888889 0.0154440154440154
GO:BP GO:0010975 regulation of neuron projection development 0.0254810572472238 451 27 4 0.148148148148148 0.00886917960088692
GO:BP GO:0055008 cardiac muscle tissue morphogenesis 0.0255020241309753 59 100 3 0.03 0.0508474576271186
GO:BP GO:0002062 chondrocyte differentiation 0.0255020241309753 108 110 4 0.0363636363636364 0.037037037037037
GO:BP GO:0009653 anatomical structure morphogenesis 0.0256786775488935 2797 110 28 0.254545454545455 0.0100107257776189
GO:BP GO:0030003 cellular cation homeostasis 0.0256786775488935 673 70 8 0.114285714285714 0.011887072808321
GO:BP GO:0006885 regulation of pH 0.0258186600779801 103 58 3 0.0517241379310345 0.029126213592233
GO:BP GO:0045595 regulation of cell differentiation 0.0258186600779801 1679 18 6 0.333333333333333 0.00357355568790947
GO:BP GO:0006468 protein phosphorylation 0.0258186600779801 1668 108 19 0.175925925925926 0.0113908872901679
GO:BP GO:0031399 regulation of protein modification process 0.0258479894784302 1671 108 19 0.175925925925926 0.0113704368641532
GO:BP GO:0022408 negative regulation of cell-cell adhesion 0.0258479894784302 194 100 5 0.05 0.0257731958762887
GO:BP GO:0035296 regulation of tube diameter 0.0264221965055443 135 90 4 0.0444444444444444 0.0296296296296296
GO:BP GO:0042325 regulation of phosphorylation 0.0264221965055443 1431 108 17 0.157407407407407 0.0118798043326345
GO:BP GO:0050865 regulation of cell activation 0.0264221965055443 655 10 3 0.3 0.00458015267175573
GO:BP GO:0006821 chloride transport 0.0264221965055443 109 56 3 0.0535714285714286 0.0275229357798165
GO:BP GO:0008104 protein localization 0.0264221965055443 2770 72 20 0.277777777777778 0.0072202166064982
GO:BP GO:0097746 blood vessel diameter maintenance 0.0264221965055443 135 90 4 0.0444444444444444 0.0296296296296296
GO:BP GO:0035150 regulation of tube size 0.0264443351605063 136 90 4 0.0444444444444444 0.0294117647058824
GO:BP GO:0010648 negative regulation of cell communication 0.0264443351605063 1468 27 7 0.259259259259259 0.00476839237057221
GO:BP GO:0070201 regulation of establishment of protein localization 0.0264443351605063 611 78 8 0.102564102564103 0.0130932896890344
GO:BP GO:0023057 negative regulation of signaling 0.0266579329523896 1471 27 7 0.259259259259259 0.00475866757307954
GO:BP GO:0006687 glycosphingolipid metabolic process 0.0268075059490784 68 91 3 0.032967032967033 0.0441176470588235
GO:BP GO:0006464 cellular protein modification process 0.0268403086647781 4041 111 37 0.333333333333333 0.00915614946795348
GO:BP GO:0036211 protein modification process 0.0268403086647781 4041 111 37 0.333333333333333 0.00915614946795348
GO:BP GO:0090087 regulation of peptide transport 0.0271348426644013 618 78 8 0.102564102564103 0.0129449838187702
GO:BP GO:0051493 regulation of cytoskeleton organization 0.027321617486958 531 72 7 0.0972222222222222 0.0131826741996234
GO:BP GO:1902930 regulation of alcohol biosynthetic process 0.0275313968642936 78 81 3 0.037037037037037 0.0384615384615385
GO:BP GO:0006575 cellular modified amino acid metabolic process 0.0275313968642936 199 101 5 0.0495049504950495 0.0251256281407035
GO:BP GO:0001952 regulation of cell-matrix adhesion 0.0276069262042647 127 50 3 0.06 0.0236220472440945
GO:BP GO:0048584 positive regulation of response to stimulus 0.0278934134190925 2344 27 9 0.333333333333333 0.00383959044368601
GO:BP GO:0071495 cellular response to endogenous stimulus 0.0279685434507238 1422 110 17 0.154545454545455 0.0119549929676512
GO:BP GO:1901607 alpha-amino acid biosynthetic process 0.0280202398612222 68 94 3 0.0319148936170213 0.0441176470588235
GO:BP GO:0050767 regulation of neurogenesis 0.0280449708938771 366 18 3 0.166666666666667 0.00819672131147541
GO:BP GO:0031589 cell-substrate adhesion 0.0282147333073887 367 18 3 0.166666666666667 0.00817438692098093
GO:BP GO:0006869 lipid transport 0.0282694163624379 480 101 8 0.0792079207920792 0.0166666666666667
GO:BP GO:0043009 chordate embryonic development 0.0285323581005307 616 114 10 0.087719298245614 0.0162337662337662
GO:BP GO:0046513 ceramide biosynthetic process 0.0285323581005307 71 91 3 0.032967032967033 0.0422535211267606
GO:BP GO:0030155 regulation of cell adhesion 0.0286513277077519 748 18 4 0.222222222222222 0.0053475935828877
GO:BP GO:0080134 regulation of response to stress 0.029272377476472 1443 10 4 0.4 0.00277200277200277
GO:BP GO:0030902 hindbrain development 0.029272377476472 152 85 4 0.0470588235294118 0.0263157894736842
GO:BP GO:0031347 regulation of defense response 0.029272377476472 704 10 3 0.3 0.00426136363636364
GO:BP GO:0060562 epithelial tube morphogenesis 0.0295338813790822 329 118 7 0.0593220338983051 0.0212765957446809
GO:BP GO:0048878 chemical homeostasis 0.029557340664555 1229 18 5 0.277777777777778 0.00406834825061025
GO:BP GO:0051241 negative regulation of multicellular organismal process 0.029643339689253 1160 72 11 0.152777777777778 0.00948275862068966
GO:BP GO:0045861 negative regulation of proteolysis 0.0299401544174189 359 19 3 0.157894736842105 0.00835654596100279
GO:BP GO:0090288 negative regulation of cellular response to growth factor stimulus 0.0301999238474581 119 110 4 0.0363636363636364 0.0336134453781513
GO:BP GO:0042310 vasoconstriction 0.0306464310932803 83 81 3 0.037037037037037 0.036144578313253
GO:BP GO:1901564 organonitrogen compound metabolic process 0.0307831044693427 6792 111 55 0.495495495495495 0.00809776207302709
GO:BP GO:0008283 cell population proliferation 0.0312641228586311 2054 85 18 0.211764705882353 0.00876338851022395
GO:BP GO:0051604 protein maturation 0.0314505061223185 306 98 6 0.0612244897959184 0.0196078431372549
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.0314771634424857 1477 108 17 0.157407407407407 0.011509817197021
GO:BP GO:0071674 mononuclear cell migration 0.0314771634424857 191 70 4 0.0571428571428571 0.0209424083769634
GO:BP GO:0046173 polyol biosynthetic process 0.0316301597589741 64 107 3 0.0280373831775701 0.046875
GO:BP GO:0046889 positive regulation of lipid biosynthetic process 0.0317731852369483 88 78 3 0.0384615384615385 0.0340909090909091
GO:BP GO:1903522 regulation of blood circulation 0.0317731852369483 301 100 6 0.06 0.0199335548172757
GO:BP GO:0045937 positive regulation of phosphate metabolic process 0.0319677712065551 1001 108 13 0.12037037037037 0.012987012987013
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 0.0319677712065551 1001 108 13 0.12037037037037 0.012987012987013
GO:BP GO:0071702 organic substance transport 0.0319959922683797 2766 24 9 0.375 0.00325379609544469
GO:BP GO:0060415 muscle tissue morphogenesis 0.0319959922683797 69 100 3 0.03 0.0434782608695652
GO:BP GO:0051130 positive regulation of cellular component organization 0.0325280816681853 1153 84 12 0.142857142857143 0.01040763226366
GO:BP GO:0009792 embryo development ending in birth or egg hatching 0.0326747885409588 635 114 10 0.087719298245614 0.015748031496063
GO:BP GO:0048731 system development 0.032888492944207 5052 10 7 0.7 0.00138558986539984
GO:BP GO:0006631 fatty acid metabolic process 0.0331207414105499 404 54 5 0.0925925925925926 0.0123762376237624
GO:BP GO:0071375 cellular response to peptide hormone stimulus 0.0332172115625544 340 64 5 0.078125 0.0147058823529412
GO:BP GO:0046467 membrane lipid biosynthetic process 0.0332339596703506 151 91 4 0.043956043956044 0.0264900662251656
GO:BP GO:0034329 cell junction assembly 0.0332619812992877 438 32 4 0.125 0.0091324200913242
GO:BP GO:0031424 keratinization 0.0332633234730376 224 32 3 0.09375 0.0133928571428571
GO:BP GO:0051093 negative regulation of developmental process 0.0332662118037894 977 15 4 0.266666666666667 0.00409416581371546
GO:BP GO:0006066 alcohol metabolic process 0.0335357859003403 382 81 6 0.0740740740740741 0.0157068062827225
GO:BP GO:0010628 positive regulation of gene expression 0.03393967555024 1160 20 5 0.25 0.00431034482758621
GO:BP GO:0051345 positive regulation of hydrolase activity 0.0342119776575495 783 109 11 0.100917431192661 0.0140485312899106
GO:BP GO:0120036 plasma membrane bounded cell projection organization 0.0344418448247484 1569 112 18 0.160714285714286 0.011472275334608
GO:BP GO:1903532 positive regulation of secretion by cell 0.0350257104912013 285 78 5 0.0641025641025641 0.0175438596491228
GO:BP GO:0019725 cellular homeostasis 0.0353482131471481 981 33 6 0.181818181818182 0.00611620795107034
GO:BP GO:0002709 regulation of T cell mediated immunity 0.0354569398168227 74 100 3 0.03 0.0405405405405405
GO:BP GO:0035637 multicellular organismal signaling 0.0356548292480698 204 70 4 0.0571428571428571 0.0196078431372549
GO:BP GO:0008652 cellular amino acid biosynthetic process 0.035720310635308 79 94 3 0.0319148936170213 0.0379746835443038
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.0357845630375814 460 69 6 0.0869565217391304 0.0130434782608696
GO:BP GO:0051017 actin filament bundle assembly 0.0358560136050045 161 89 4 0.0449438202247191 0.0248447204968944
GO:BP GO:0007165 signal transduction 0.0358560136050045 6309 27 16 0.592592592592593 0.00253605959740054
GO:BP GO:0055080 cation homeostasis 0.0358560136050045 750 70 8 0.114285714285714 0.0106666666666667
GO:BP GO:0046503 glycerolipid catabolic process 0.035866717578404 74 101 3 0.0297029702970297 0.0405405405405405
GO:BP GO:0008610 lipid biosynthetic process 0.0359619418648208 740 101 10 0.099009900990099 0.0135135135135135
GO:BP GO:0048858 cell projection morphogenesis 0.0360870231501539 682 77 8 0.103896103896104 0.0117302052785924
GO:BP GO:0048523 negative regulation of cellular process 0.0365704791268297 5139 27 14 0.518518518518518 0.00272426542128819
GO:BP GO:0048644 muscle organ morphogenesis 0.036779661238253 76 100 3 0.03 0.0394736842105263
GO:BP GO:0010243 response to organonitrogen compound 0.036779661238253 1085 22 5 0.227272727272727 0.00460829493087558
GO:BP GO:0019538 protein metabolic process 0.036779661238253 5808 111 48 0.432432432432432 0.00826446280991736
GO:BP GO:0071900 regulation of protein serine/threonine kinase activity 0.036779661238253 503 64 6 0.09375 0.0119284294234592
GO:BP GO:0048513 animal organ development 0.036779661238253 3672 62 21 0.338709677419355 0.00571895424836601
GO:BP GO:0006639 acylglycerol metabolic process 0.036779661238253 141 54 3 0.0555555555555556 0.0212765957446809
GO:BP GO:0061572 actin filament bundle organization 0.0371953794195812 164 89 4 0.0449438202247191 0.024390243902439
GO:BP GO:0006638 neutral lipid metabolic process 0.0372109066004475 142 54 3 0.0555555555555556 0.0211267605633803
GO:BP GO:0033554 cellular response to stress 0.0372109066004475 2111 8 4 0.5 0.00189483657034581
GO:BP GO:0032501 multicellular organismal process 0.0376884420682892 7946 118 65 0.550847457627119 0.00818021646111251
GO:BP GO:0010720 positive regulation of cell development 0.0376884420682892 302 107 6 0.0560747663551402 0.0198675496688742
GO:BP GO:0051960 regulation of nervous system development 0.0376884420682892 443 18 3 0.166666666666667 0.00677200902934537
GO:BP GO:0032880 regulation of protein localization 0.0377077206057727 922 26 5 0.192307692307692 0.00542299349240781
GO:BP GO:0030036 actin cytoskeleton organization 0.0379034322854158 709 107 10 0.0934579439252336 0.0141043723554302
GO:BP GO:0051098 regulation of binding 0.0381385107758223 365 64 5 0.078125 0.0136986301369863
GO:BP GO:0050793 regulation of developmental process 0.0381474370863709 2605 18 7 0.388888888888889 0.00268714011516315
GO:BP GO:0008544 epidermis development 0.038194248414625 475 32 4 0.125 0.00842105263157895
GO:BP GO:0046486 glycerolipid metabolic process 0.0383727841316475 436 54 5 0.0925925925925926 0.0114678899082569
GO:BP GO:0032869 cellular response to insulin stimulus 0.0384550479284236 235 64 4 0.0625 0.0170212765957447
GO:BP GO:0055117 regulation of cardiac muscle contraction 0.0384550479284236 79 100 3 0.03 0.0379746835443038
GO:BP GO:0032990 cell part morphogenesis 0.0384550479284236 699 77 8 0.103896103896104 0.011444921316166
GO:BP GO:0023056 positive regulation of signaling 0.0385957332146014 1782 72 14 0.194444444444444 0.00785634118967452
GO:BP GO:0030030 cell projection organization 0.0387645660395248 1609 112 18 0.160714285714286 0.0111870727159727
GO:BP GO:0007043 cell-cell junction assembly 0.0389785902133581 151 100 4 0.04 0.0264900662251656
GO:BP GO:0043270 positive regulation of ion transport 0.0389791764461974 694 78 8 0.102564102564103 0.0115273775216138
GO:BP GO:0070887 cellular response to chemical stimulus 0.0391655128604198 3393 110 31 0.281818181818182 0.00913645741231948
GO:BP GO:0009628 response to abiotic stimulus 0.0391655128604198 1261 81 12 0.148148148148148 0.00951625693893735
GO:BP GO:0045580 regulation of T cell differentiation 0.0392068068019029 152 100 4 0.04 0.0263157894736842
GO:BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.0392068068019029 152 100 4 0.04 0.0263157894736842
GO:BP GO:0045732 positive regulation of protein catabolic process 0.0395213305705885 237 100 5 0.05 0.0210970464135021
GO:BP GO:0015031 protein transport 0.0404466207807192 1929 24 7 0.291666666666667 0.00362882322446864
GO:BP GO:0032787 monocarboxylic acid metabolic process 0.0404466207807192 658 13 3 0.230769230769231 0.00455927051671732
GO:BP GO:0008284 positive regulation of cell population proliferation 0.0404911511275436 982 9 3 0.333333333333333 0.00305498981670061
GO:BP GO:0046394 carboxylic acid biosynthetic process 0.0404911511275436 330 101 6 0.0594059405940594 0.0181818181818182
GO:BP GO:1903364 positive regulation of cellular protein catabolic process 0.0406592326683724 154 100 4 0.04 0.025974025974026
GO:BP GO:0007040 lysosome organization 0.0406592326683724 72 114 3 0.0263157894736842 0.0416666666666667
GO:BP GO:0080171 lytic vacuole organization 0.0406592326683724 72 114 3 0.0263157894736842 0.0416666666666667
GO:BP GO:0043412 macromolecule modification 0.0410042899894829 4257 72 26 0.361111111111111 0.00610758750293634
GO:BP GO:0071692 protein localization to extracellular region 0.0413641539531417 392 86 6 0.0697674418604651 0.0153061224489796
GO:BP GO:0009725 response to hormone 0.0414714609188866 921 98 11 0.112244897959184 0.011943539630836
GO:BP GO:0030178 negative regulation of Wnt signaling pathway 0.0417436330493601 218 72 4 0.0555555555555556 0.018348623853211
GO:BP GO:0070085 glycosylation 0.0418375397962503 264 92 5 0.0543478260869565 0.0189393939393939
GO:BP GO:0000902 cell morphogenesis 0.0420169614037307 1037 54 8 0.148148148148148 0.0077145612343298
GO:BP GO:0051047 positive regulation of secretion 0.0426229805294864 314 78 5 0.0641025641025641 0.0159235668789809
GO:BP GO:0050896 response to stimulus 0.0427327962018932 9407 111 70 0.630630630630631 0.00744126714149038
GO:BP GO:0055114 obsolete oxidation-reduction process 0.0428309092899392 745 90 9 0.1 0.0120805369127517
GO:BP GO:0016053 organic acid biosynthetic process 0.0428309092899392 338 101 6 0.0594059405940594 0.0177514792899408
GO:BP GO:0015833 peptide transport 0.0428309092899392 1971 24 7 0.291666666666667 0.00355149670218163
GO:BP GO:0051099 positive regulation of binding 0.0428309092899392 174 49 3 0.0612244897959184 0.0172413793103448
GO:BP GO:1901698 response to nitrogen compound 0.0430567684193423 1172 22 5 0.227272727272727 0.00426621160409556
GO:BP GO:0052548 regulation of endopeptidase activity 0.0431147536489849 437 37 4 0.108108108108108 0.0091533180778032
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.0431560989282161 1227 85 12 0.141176470588235 0.0097799511002445
GO:BP GO:0043269 regulation of ion transport 0.0431560989282161 1379 26 6 0.230769230769231 0.00435097897026831
GO:BP GO:0042127 regulation of cell population proliferation 0.0432091894576985 1774 10 4 0.4 0.00225479143179256
GO:BP GO:0045597 positive regulation of cell differentiation 0.0436452319730559 879 77 9 0.116883116883117 0.0102389078498294
GO:BP GO:0030217 T cell differentiation 0.0436452319730559 260 62 4 0.0645161290322581 0.0153846153846154
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.0450372992458393 3087 108 28 0.259259259259259 0.0090702947845805
GO:BP GO:0007275 multicellular organism development 0.0450903633949942 5613 10 7 0.7 0.00124710493497239
GO:BP GO:0042886 amide transport 0.0450903633949942 2007 24 7 0.291666666666667 0.00348779272546089
GO:BP GO:0071695 anatomical structure maturation 0.0450903633949942 224 112 5 0.0446428571428571 0.0223214285714286
GO:BP GO:1901652 response to peptide 0.045380165835028 551 64 6 0.09375 0.0108892921960073
GO:BP GO:0030097 hemopoiesis 0.0464509469427392 928 62 8 0.129032258064516 0.00862068965517241
GO:BP GO:0044267 cellular protein metabolic process 0.0464509469427392 5229 72 30 0.416666666666667 0.0057372346528973
GO:BP GO:0072659 protein localization to plasma membrane 0.0464509469427392 283 32 3 0.09375 0.0106007067137809
GO:BP GO:0030509 BMP signaling pathway 0.0464576547523383 158 105 4 0.0380952380952381 0.0253164556962025
GO:BP GO:0021915 neural tube development 0.0464576547523383 158 105 4 0.0380952380952381 0.0253164556962025
GO:BP GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 0.0466190474472576 90 100 3 0.03 0.0333333333333333
GO:BP GO:0042060 wound healing 0.0470546334284763 549 17 3 0.176470588235294 0.00546448087431694
GO:BP GO:0002819 regulation of adaptive immune response 0.0470929151169489 167 100 4 0.04 0.0239520958083832
GO:BP GO:0045184 establishment of protein localization 0.0470929151169489 2035 24 7 0.291666666666667 0.00343980343980344
GO:BP GO:0031324 negative regulation of cellular metabolic process 0.0470929151169489 2719 27 9 0.333333333333333 0.00331004045605002
GO:BP GO:1901615 organic hydroxy compound metabolic process 0.0471815992450928 571 81 7 0.0864197530864197 0.0122591943957968
GO:BP GO:0071310 cellular response to organic substance 0.0475552093631493 2776 110 26 0.236363636363636 0.00936599423631124
GO:BP GO:0006793 phosphorus metabolic process 0.0475552093631493 3114 108 28 0.259259259259259 0.00899165061014772
GO:BP GO:0071277 cellular response to calcium ion 0.0475552093631493 84 109 3 0.0275229357798165 0.0357142857142857
GO:BP GO:0016043 cellular component organization 0.0475552093631493 6566 116 54 0.46551724137931 0.00822418519646665
GO:BP GO:0043408 regulation of MAPK cascade 0.0475552093631493 730 64 7 0.109375 0.00958904109589041
GO:BP GO:0016310 phosphorylation 0.0475552093631493 2138 108 21 0.194444444444444 0.009822263797942
GO:BP GO:1902107 positive regulation of leukocyte differentiation 0.0483732148370437 157 59 3 0.0508474576271186 0.0191082802547771
GO:BP GO:1903708 positive regulation of hemopoiesis 0.0483732148370437 157 59 3 0.0508474576271186 0.0191082802547771
GO:BP GO:0044070 regulation of anion transport 0.0484806282497081 896 78 9 0.115384615384615 0.0100446428571429
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0488598925102351 253 37 3 0.0810810810810811 0.0118577075098814
GO:BP GO:0009100 glycoprotein metabolic process 0.0489373304575851 424 110 7 0.0636363636363636 0.0165094339622642
GO:BP GO:0035304 regulation of protein dephosphorylation 0.0489373304575851 146 64 3 0.046875 0.0205479452054795
GO:BP GO:0048522 positive regulation of cellular process 0.0489373304575851 5757 85 37 0.435294117647059 0.00642695848532222
GO:BP GO:0006493 protein O-linked glycosylation 0.0494153360498298 102 92 3 0.0326086956521739 0.0294117647058824
GO:BP GO:0015698 inorganic anion transport 0.0498810714800679 169 56 3 0.0535714285714286 0.0177514792899408
GO:BP GO:0008286 insulin receptor signaling pathway 0.0499164209349858 148 64 3 0.046875 0.0202702702702703
GO:BP GO:0006672 ceramide metabolic process 0.0499183285583205 104 91 3 0.032967032967033 0.0288461538461538
GO:CC GO:0071944 cell periphery 1.62241219569892e-06 6169 102 62 0.607843137254902 0.0100502512562814
GO:CC GO:1903561 extracellular vesicle 8.01670129374034e-06 2261 90 30 0.333333333333333 0.0132684652808492
GO:CC GO:0016020 membrane 8.01670129374034e-06 9838 47 42 0.893617021276596 0.00426916039845497
GO:CC GO:0043230 extracellular organelle 8.01670129374034e-06 2263 90 30 0.333333333333333 0.0132567388422448
GO:CC GO:0070062 extracellular exosome 8.57845288873102e-06 2176 90 29 0.322222222222222 0.0133272058823529
GO:CC GO:0005886 plasma membrane 8.57845288873102e-06 5681 102 56 0.549019607843137 0.00985741946840345
GO:CC GO:0005576 extracellular region 8.841924670739e-06 4567 16 14 0.875 0.00306546967374644
GO:CC GO:0045177 apical part of cell 2.08197183398568e-05 431 43 9 0.209302325581395 0.0208816705336427
GO:CC GO:0005615 extracellular space 2.50605316100499e-05 3594 75 33 0.44 0.00918196994991653
GO:CC GO:0030141 secretory granule 2.71103937173497e-05 851 55 13 0.236363636363636 0.0152761457109283
GO:CC GO:0016324 apical plasma membrane 4.62844221411429e-05 361 43 8 0.186046511627907 0.0221606648199446
GO:CC GO:0031982 vesicle 4.68082579157003e-05 4055 64 31 0.484375 0.00764488286066584
GO:CC GO:0012505 endomembrane system 5.99502702330328e-05 4640 94 44 0.468085106382979 0.00948275862068966
GO:CC GO:0005887 integral component of plasma membrane 6.43109475874701e-05 1645 85 22 0.258823529411765 0.0133738601823708
GO:CC GO:0009925 basal plasma membrane 7.04238499527012e-05 247 18 5 0.277777777777778 0.0202429149797571
GO:CC GO:0099503 secretory vesicle 8.35993910133208e-05 1020 25 9 0.36 0.00882352941176471
GO:CC GO:0045178 basal part of cell 8.76625318055454e-05 265 18 5 0.277777777777778 0.0188679245283019
GO:CC GO:0031226 intrinsic component of plasma membrane 0.000109821075070813 1726 85 22 0.258823529411765 0.0127462340672074
GO:CC GO:0070161 anchoring junction 0.000135723472017468 836 18 7 0.388888888888889 0.00837320574162679
GO:CC GO:0031224 intrinsic component of membrane 0.000220778051881872 5868 86 46 0.534883720930233 0.00783912747102931
GO:CC GO:0098590 plasma membrane region 0.00059656370477901 1240 33 10 0.303030303030303 0.00806451612903226
GO:CC GO:0016021 integral component of membrane 0.000623426057808592 5711 86 44 0.511627906976744 0.00770443004727718
GO:CC GO:0031090 organelle membrane 0.000823505250132707 3612 78 30 0.384615384615385 0.00830564784053156
GO:CC GO:0016323 basolateral plasma membrane 0.000823505250132707 222 18 4 0.222222222222222 0.018018018018018
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.00137176939226093 324 64 7 0.109375 0.0216049382716049
GO:CC GO:0005911 cell-cell junction 0.00137176939226093 494 43 7 0.162790697674419 0.01417004048583
GO:CC GO:0097708 intracellular vesicle 0.00137176939226093 2428 64 20 0.3125 0.00823723228995058
GO:CC GO:0031410 cytoplasmic vesicle 0.00137176939226093 2424 64 20 0.3125 0.00825082508250825
GO:CC GO:0034774 secretory granule lumen 0.00137176939226093 320 64 7 0.109375 0.021875
GO:CC GO:0031983 vesicle lumen 0.00137176939226093 326 64 7 0.109375 0.0214723926380368
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.00137176939226093 779 20 6 0.3 0.00770218228498074
GO:CC GO:0012506 vesicle membrane 0.00144935820199913 800 20 6 0.3 0.0075
GO:CC GO:0005783 endoplasmic reticulum 0.00240403963728308 1982 94 22 0.234042553191489 0.0110998990918264
GO:CC GO:0098588 bounding membrane of organelle 0.00247751220249501 2158 65 18 0.276923076923077 0.00834105653382762
GO:CC GO:0098852 lytic vacuole membrane 0.00247751220249501 383 62 7 0.112903225806452 0.0182767624020888
GO:CC GO:0005765 lysosomal membrane 0.00247751220249501 383 62 7 0.112903225806452 0.0182767624020888
GO:CC GO:0030667 secretory granule membrane 0.00248677524239134 303 20 4 0.2 0.0132013201320132
GO:CC GO:0042581 specific granule 0.00278063527825647 158 39 4 0.102564102564103 0.0253164556962025
GO:CC GO:0031984 organelle subcompartment 0.00321079147089088 1773 94 20 0.212765957446809 0.0112803158488438
GO:CC GO:0005902 microvillus 0.00372642205617794 91 31 3 0.0967741935483871 0.032967032967033
GO:CC GO:0005774 vacuolar membrane 0.00479165817670467 441 62 7 0.112903225806452 0.0158730158730159
GO:CC GO:0005766 primary lysosome 0.0048693426018187 154 85 5 0.0588235294117647 0.0324675324675325
GO:CC GO:0005764 lysosome 0.0048693426018187 712 64 9 0.140625 0.0126404494382022
GO:CC GO:0042582 azurophil granule 0.0048693426018187 154 85 5 0.0588235294117647 0.0324675324675325
GO:CC GO:0000323 lytic vacuole 0.0048693426018187 712 64 9 0.140625 0.0126404494382022
GO:CC GO:0005802 trans-Golgi network 0.00501007219516628 250 111 7 0.0630630630630631 0.028
GO:CC GO:0019898 extrinsic component of membrane 0.00647825846270328 313 27 4 0.148148148148148 0.012779552715655
GO:CC GO:0009986 cell surface 0.00647825846270328 899 17 5 0.294117647058824 0.00556173526140156
GO:CC GO:0010008 endosome membrane 0.00727775397547414 505 61 7 0.114754098360656 0.0138613861386139
GO:CC GO:0005769 early endosome 0.00829684154423743 378 61 6 0.0983606557377049 0.0158730158730159
GO:CC GO:0005773 vacuole 0.00861779384485713 810 64 9 0.140625 0.0111111111111111
GO:CC GO:0005768 endosome 0.00861779384485713 987 85 12 0.141176470588235 0.0121580547112462
GO:CC GO:0030054 cell junction 0.00967476805955728 2105 32 10 0.3125 0.00475059382422803
GO:CC GO:0005795 Golgi stack 0.00978012188783323 149 111 5 0.045045045045045 0.0335570469798658
GO:CC GO:0098791 Golgi apparatus subcompartment 0.0103725310463288 885 111 13 0.117117117117117 0.0146892655367232
GO:CC GO:0098796 membrane protein complex 0.0103725310463288 1322 103 16 0.155339805825243 0.0121028744326778
GO:CC GO:0005788 endoplasmic reticulum lumen 0.0111043957153214 307 111 7 0.0630630630630631 0.0228013029315961
GO:CC GO:0031225 anchored component of membrane 0.0124722933295071 174 30 3 0.1 0.0172413793103448
GO:CC GO:0005775 vacuolar lumen 0.0135948744980524 174 64 4 0.0625 0.0229885057471264
GO:CC GO:0005912 adherens junction 0.0144352274327356 173 32 3 0.09375 0.0173410404624277
GO:CC GO:0005789 endoplasmic reticulum membrane 0.0158889831698481 1117 94 13 0.138297872340426 0.0116383169203223
GO:CC GO:0098827 endoplasmic reticulum subcompartment 0.0163109073965904 1122 94 13 0.138297872340426 0.0115864527629234
GO:CC GO:0035578 azurophil granule lumen 0.0164827770389847 91 64 3 0.046875 0.032967032967033
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 0.0176944280899038 1139 94 13 0.138297872340426 0.0114135206321334
GO:CC GO:0098858 actin-based cell projection 0.0228876163349896 220 31 3 0.0967741935483871 0.0136363636363636
GO:CC GO:1902495 transmembrane transporter complex 0.0248629552806616 325 43 4 0.0930232558139535 0.0123076923076923
GO:CC GO:0005604 basement membrane 0.0261355834449958 97 75 3 0.04 0.0309278350515464
GO:CC GO:0005925 focal adhesion 0.0264937359558186 420 18 3 0.166666666666667 0.00714285714285714
GO:CC GO:1990351 transporter complex 0.0273217478073605 340 43 4 0.0930232558139535 0.0117647058823529
GO:CC GO:0030055 cell-substrate junction 0.0273217478073605 427 18 3 0.166666666666667 0.00702576112412178
GO:CC GO:0055037 recycling endosome 0.0282562359147463 188 78 4 0.0512820512820513 0.0212765957446809
GO:CC GO:0031902 late endosome membrane 0.0357798942752518 140 61 3 0.0491803278688525 0.0214285714285714
GO:CC GO:0031253 cell projection membrane 0.036150628221186 343 102 6 0.0588235294117647 0.0174927113702624
GO:CC GO:0098797 plasma membrane protein complex 0.0367845586448458 694 100 9 0.09 0.0129682997118156
GO:CC GO:0005794 Golgi apparatus 0.0368478651401683 1623 92 15 0.16304347826087 0.00924214417744917
GO:CC GO:0005770 late endosome 0.0375038495473979 275 61 4 0.0655737704918033 0.0145454545454545
GO:CC GO:0120025 plasma membrane bounded cell projection 0.0375038495473979 2229 33 9 0.272727272727273 0.00403768506056528
GO:CC GO:0042995 cell projection 0.0404205945847935 2330 116 23 0.198275862068966 0.00987124463519313
GO:CC GO:0005791 rough endoplasmic reticulum 0.0421809147974282 86 111 3 0.027027027027027 0.0348837209302326
GO:CC GO:0062023 collagen-containing extracellular matrix 0.0433931005410219 421 90 6 0.0666666666666667 0.0142517814726841
GO:CC GO:0031012 extracellular matrix 0.0483086791055262 562 90 7 0.0777777777777778 0.0124555160142349
GO:CC GO:0030312 external encapsulating structure 0.048391896263807 563 90 7 0.0777777777777778 0.0124333925399645
GO:MF GO:0030228 lipoprotein particle receptor activity 0.000562766820887831 17 23 3 0.130434782608696 0.176470588235294
GO:MF GO:0038024 cargo receptor activity 0.000854488426537365 78 25 4 0.16 0.0512820512820513
GO:MF GO:1901681 sulfur compound binding 0.000918818108827687 264 19 5 0.263157894736842 0.0189393939393939
GO:MF GO:0031418 L-ascorbic acid binding 0.00638603626625317 21 90 3 0.0333333333333333 0.142857142857143
GO:MF GO:0046983 protein dimerization activity 0.00722150320967355 1069 16 6 0.375 0.00561272217025257
GO:MF GO:0008201 heparin binding 0.019024510229026 168 19 3 0.157894736842105 0.0178571428571429
GO:MF GO:0042803 protein homodimerization activity 0.019024510229026 676 12 4 0.333333333333333 0.00591715976331361
GO:MF GO:0050660 flavin adenine dinucleotide binding 0.0220362062089257 83 94 4 0.0425531914893617 0.0481927710843374
GO:MF GO:0044877 protein-containing complex binding 0.0223180820304181 1287 33 8 0.242424242424242 0.00621600621600622
GO:MF GO:0042802 identical protein binding 0.0223180820304181 2067 13 6 0.461538461538462 0.00290275761973875
GO:MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 0.0223180820304181 167 90 5 0.0555555555555556 0.029940119760479
GO:MF GO:0016706 2-oxoglutarate-dependent dioxygenase activity 0.0223180820304181 48 90 3 0.0333333333333333 0.0625
GO:MF GO:0033218 amide binding 0.0223180820304181 389 26 4 0.153846153846154 0.0102827763496144
GO:MF GO:0030546 signaling receptor activator activity 0.0223180820304181 501 9 3 0.333333333333333 0.00598802395209581
GO:MF GO:0030545 receptor regulator activity 0.0223180820304181 545 9 3 0.333333333333333 0.0055045871559633
GO:MF GO:0048018 receptor ligand activity 0.0223180820304181 494 9 3 0.333333333333333 0.00607287449392713
GO:MF GO:1901618 organic hydroxy compound transmembrane transporter activity 0.0223180820304181 50 78 3 0.0384615384615385 0.06
GO:MF GO:0051213 dioxygenase activity 0.0223180820304181 96 90 4 0.0444444444444444 0.0416666666666667
GO:MF GO:0005539 glycosaminoglycan binding 0.0223180820304181 238 19 3 0.157894736842105 0.0126050420168067
GO:MF GO:0097367 carbohydrate derivative binding 0.022868746091959 2285 78 19 0.243589743589744 0.00831509846827133
GO:MF GO:0042626 ATPase-coupled transmembrane transporter activity 0.0251176982810632 67 78 3 0.0384615384615385 0.0447761194029851
GO:MF GO:0016757 transferase activity, transferring glycosyl groups 0.0251176982810632 283 91 6 0.0659340659340659 0.0212014134275618
GO:MF GO:0005544 calcium-dependent phospholipid binding 0.0261886465696789 54 101 3 0.0297029702970297 0.0555555555555556
GO:MF GO:0098632 cell-cell adhesion mediator activity 0.0261886465696789 49 112 3 0.0267857142857143 0.0612244897959184
GO:MF GO:0019899 enzyme binding 0.0266005345553936 2074 24 8 0.333333333333333 0.0038572806171649
GO:MF GO:0015399 primary active transmembrane transporter activity 0.0293848303397212 74 78 3 0.0384615384615385 0.0405405405405405
GO:MF GO:0016491 oxidoreductase activity 0.0306401668446406 771 90 10 0.111111111111111 0.012970168612192
GO:MF GO:0008047 enzyme activator activity 0.0321012982917527 540 109 9 0.0825688073394495 0.0166666666666667
GO:MF GO:0048029 monosaccharide binding 0.0336350852812091 71 90 3 0.0333333333333333 0.0422535211267606
GO:MF GO:0098631 cell adhesion mediator activity 0.0339658615843823 58 112 3 0.0267857142857143 0.0517241379310345
GO:MF GO:0019842 vitamin binding 0.0398365765007183 149 94 4 0.0425531914893617 0.0268456375838926
GO:MF GO:0005102 signaling receptor binding 0.0422465497651898 1672 27 7 0.259259259259259 0.0041866028708134
GO:MF GO:0015075 ion transmembrane transporter activity 0.0434380922746163 956 82 10 0.121951219512195 0.0104602510460251
GO:MF GO:0019901 protein kinase binding 0.0469767807872361 673 24 4 0.166666666666667 0.00594353640416048
GO:MF GO:0030246 carbohydrate binding 0.0469767807872361 275 90 5 0.0555555555555556 0.0181818181818182
GO:MF GO:0015318 inorganic molecular entity transmembrane transporter activity 0.0469767807872361 831 82 9 0.109756097560976 0.0108303249097473
GO:MF GO:0005509 calcium ion binding 0.0470937273120405 721 111 10 0.0900900900900901 0.013869625520111
REAC REAC:R-HSA-202733 Cell surface interactions at the vascular wall 0.0173701228363439 190 16 4 0.25 0.0210526315789474
REAC REAC:R-HSA-6798695 Neutrophil degranulation 0.0447137976349542 474 24 6 0.25 0.0126582278481013
TF TF:M09886 Factor: COUP-TF1; motif: GRGGKSARAGGTCAGNG 5.48415138362485e-06 5888 58 40 0.689655172413793 0.00679347826086957
TF TF:M00763_1 Factor: PPAR; motif: TGACCTTTGNCCY; match class: 1 5.68236671226013e-05 941 33 12 0.363636363636364 0.0127523910733262
TF TF:M08870 Factor: DEC1; motif: NCNCACRTGNSC 0.000149041272330163 7944 57 43 0.754385964912281 0.00541289023162135
TF TF:M00762 Factor: PPAR,; motif: RGGNCAAAGGTCA 0.000303466454920115 1887 58 20 0.344827586206897 0.0105988341282459
TF TF:M03543 Factor: COUP-TF2; motif: GNCARAGGTCANRRN 0.00123402488684783 2051 54 19 0.351851851851852 0.00926377376889322
TF TF:M10491_1 Factor: ZNF586; motif: CAGGCCYRGAGG; match class: 1 0.00124893218906313 7720 75 50 0.666666666666667 0.00647668393782383
TF TF:M09591_1 Factor: AP-2gamma; motif: NTGSCCTGRGGSNN; match class: 1 0.00124893218906313 2821 108 35 0.324074074074074 0.0124069478908189
TF TF:M09897_1 Factor: Egr-1; motif: NNNNGCGKGGGYGGNRN; match class: 1 0.00154728702341671 993 109 19 0.174311926605505 0.0191339375629406
TF TF:M04896_1 Factor: AP-2alpha; motif: NNNGSCCTGRGGSN; match class: 1 0.0016755930249905 1333 108 22 0.203703703703704 0.0165041260315079
TF TF:M03876_1 Factor: Kaiso; motif: GCMGGGRGCRGS; match class: 1 0.0016755930249905 9106 110 75 0.681818181818182 0.0082363276960246
TF TF:M04811 Factor: RelA-p65; motif: BCWGGGRANNK 0.00184131422105005 7311 84 52 0.619047619047619 0.00711257009984954
TF TF:M09909 Factor: ER-alpha; motif: AGGTCASMNTGACCY 0.00203259246195553 6836 68 42 0.617647058823529 0.0061439438267993
TF TF:M09886_1 Factor: COUP-TF1; motif: GRGGKSARAGGTCAGNG; match class: 1 0.00203259246195553 1165 50 13 0.26 0.0111587982832618
TF TF:M00915_1 Factor: AP-2; motif: SNNNCCNCAGGCN; match class: 1 0.00203259246195553 4551 117 49 0.418803418803419 0.010766864425401
TF TF:M01217_1 Factor: NUR77; motif: NTGACCTTBN; match class: 1 0.00217067469919757 58 12 3 0.25 0.0517241379310345
TF TF:M07040 Factor: GKLF; motif: NNRRGRRNGNSNNN 0.00252054578427364 12705 110 92 0.836363636363636 0.00724124360487997
TF TF:M01973 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC 0.00281811705236292 6167 111 57 0.513513513513513 0.00924274363547916
TF TF:M10432 Factor: MAZ; motif: GGGMGGGGS 0.00281811705236292 9259 109 74 0.678899082568807 0.0079922237822659
TF TF:M07231_1 Factor: TFAP2A; motif: NNNNGCCYSAGGGCA; match class: 1 0.00309533001046571 1117 108 19 0.175925925925926 0.0170098478066249
TF TF:M00470 Factor: AP-2gamma; motif: GCCYNNGGS 0.00362075222596665 9422 110 75 0.681818181818182 0.00796009339842921
TF TF:M01725 Factor: TR4; motif: CSTGACCTYTS 0.00373820297981384 616 115 14 0.121739130434783 0.0227272727272727
TF TF:M09833 Factor: RXRALPHA; motif: CNNTGRCCTYTNN 0.00373820297981384 5363 50 28 0.56 0.00522095841879545
TF TF:M01972_1 Factor: EGR-1; motif: TGCGTGGGCGK; match class: 1 0.00373820297981384 1472 109 22 0.201834862385321 0.014945652173913
TF TF:M01875 Factor: ER-beta; motif: GTCANASTGRCCYNR 0.00373820297981384 6452 72 41 0.569444444444444 0.00635461872287663
TF TF:M06191_1 Factor: ZXDB; motif: NGGGGTC; match class: 1 0.00373820297981384 1279 89 18 0.202247191011236 0.0140734949179046
TF TF:M01104 Factor: MOVO-B; motif: GNGGGGG 0.00373820297981384 10261 110 79 0.718181818181818 0.00769905467303382
TF TF:M07039_1 Factor: ETF; motif: CCCCGCCCCYN; match class: 1 0.00373820297981384 13611 111 96 0.864864864864865 0.0070531188009698
TF TF:M06190_1 Factor: ZXDA; motif: NGGGGTC; match class: 1 0.00373820297981384 1279 89 18 0.202247191011236 0.0140734949179046
TF TF:M08208 Factor: E2F-3:FOXI1; motif: NGACACCGCGCCCAC 0.00373820297981384 12560 111 91 0.81981981981982 0.00724522292993631
TF TF:M08872_1 Factor: DEC; motif: NNNSCACSTGAS; match class: 1 0.00373820297981384 1938 98 24 0.244897959183673 0.0123839009287926
TF TF:M01835_1 Factor: GKLF; motif: CCTCCYN; match class: 1 0.00373820297981384 10142 95 69 0.726315789473684 0.0068033918359298
TF TF:M07329 Factor: Osx; motif: CCNCCCCCNNN 0.00373820297981384 6803 109 59 0.541284403669725 0.00867264442157871
TF TF:M10115 Factor: LRF; motif: NRGGGKCKY 0.00373820297981384 7623 111 65 0.585585585585586 0.00852682670864489
TF TF:M11796 Factor: NR1B1; motif: NRGGNCRTGACCTN 0.00379689150828831 10670 118 86 0.728813559322034 0.00805998125585754
TF TF:M00242 Factor: PPARalpha:RXRalpha; motif: CARAACTAGGNCAAAGGTCA 0.00393020871070253 1636 54 15 0.277777777777778 0.00916870415647922
TF TF:M00792_1 Factor: SMAD; motif: AGACNBCNN; match class: 1 0.00393020871070253 429 71 9 0.126760563380282 0.020979020979021
TF TF:M08019 Factor: RARA; motif: AGGTCANNYAAAGGTCA 0.00425404564764408 5530 62 33 0.532258064516129 0.00596745027124774
TF TF:M01865 Factor: BTEB3; motif: BNRNGGGAGGNGT 0.00490382782368049 9899 91 65 0.714285714285714 0.00656631983028589
TF TF:M01652_1 Factor: p53; motif: RGRCWWGYCYNGRCWWGYYY; match class: 1 0.00510797967278336 5253 68 34 0.5 0.00647249190938511
TF TF:M00763 Factor: PPAR; motif: TGACCTTTGNCCY 0.00510797967278336 5257 60 31 0.516666666666667 0.00589689937226555
TF TF:M12140_1 Factor: Egr-1; motif: NNCRCCCMCGCNN; match class: 1 0.00559216513594988 1561 109 22 0.201834862385321 0.0140935297885971
TF TF:M01036_1 Factor: COUPTF; motif: NNNNNTGACCYTTGNMCNYNGMN; match class: 1 0.00559216513594988 505 16 5 0.3125 0.0099009900990099
TF TF:M10055_1 Factor: RXR-alpha; motif: NNGNNRNNNARAGGTCANNG; match class: 1 0.00563781267542992 1082 32 9 0.28125 0.00831792975970425
TF TF:M09727 Factor: GEMIN3; motif: NCWGGRARRGRGNGNG 0.00725686200503105 8569 109 68 0.623853211009174 0.00793558174816198
TF TF:M08955_1 Factor: FXR:RXR-ALPHA; motif: NRGGTCANRGGKN; match class: 1 0.00762391725679187 3333 56 22 0.392857142857143 0.0066006600660066
TF TF:M01073 Factor: HIC1; motif: NNNGGKTGCCCSNNNNNN 0.00762391725679187 4088 47 22 0.468085106382979 0.00538160469667319
TF TF:M08299_1 Factor: FOXO1A:Elk-1; motif: RWMAACAGGAAGTN; match class: 1 0.00840797187722681 1597 7 5 0.714285714285714 0.00313087038196619
TF TF:M01857_1 Factor: AP-2alpha; motif: NGCCYSNNGSN; match class: 1 0.0084524793253722 4616 116 46 0.396551724137931 0.00996533795493934
TF TF:M00947_1 Factor: CP2/LBP-1c/LSF; motif: GCTGGNTNGNNCYNG; match class: 1 0.0084524793253722 2651 74 23 0.310810810810811 0.00867597133157299
TF TF:M01865_1 Factor: BTEB3; motif: BNRNGGGAGGNGT; match class: 1 0.00898239740017769 4218 95 37 0.389473684210526 0.0087719298245614
TF TF:M00528 Factor: PPAR; motif: WASNRGGNCAAAGGTCA 0.00908554265022589 4030 58 25 0.431034482758621 0.00620347394540943
TF TF:M09729 Factor: LUMAN; motif: CYCAGCYYCY 0.00910906334476107 10686 72 55 0.763888888888889 0.00514692120531537
TF TF:M01034 Factor: Ebox; motif: NCACSTGNCN 0.00910906334476107 4854 61 29 0.475409836065574 0.00597445405850845
TF TF:M11796_1 Factor: NR1B1; motif: NRGGNCRTGACCTN; match class: 1 0.00910906334476107 4887 111 46 0.414414414414414 0.00941272764477184
TF TF:M12262 Factor: slug; motif: RRCAGGTGCA 0.00910906334476107 2088 64 18 0.28125 0.00862068965517241
TF TF:M07249_1 Factor: ctcf; motif: CCNCNAGRKGGCRSTN; match class: 1 0.00910906334476107 2074 82 21 0.25609756097561 0.0101253616200579
TF TF:M02105 Factor: NF-E4; motif: CHCCCTCKCCWG 0.00926929084002231 2647 110 30 0.272727272727273 0.011333585190782
TF TF:M07261_1 Factor: LKLF; motif: GGGGTGGKSN; match class: 1 0.00962929493089965 4062 89 34 0.382022471910112 0.00837026095519449
TF TF:M09668 Factor: RelA-p65; motif: GGGRNTTTCCM 0.00962929493089965 3576 84 30 0.357142857142857 0.00838926174496644
TF TF:M00470_1 Factor: AP-2gamma; motif: GCCYNNGGS; match class: 1 0.00962929493089965 5600 110 50 0.454545454545455 0.00892857142857143
TF TF:M07469 Factor: Tal; motif: GWSNNCABCTGC 0.00962929493089965 4675 110 44 0.4 0.00941176470588235
TF TF:M07041 Factor: HDAC1; motif: KGCARGGTC 0.00962929493089965 12526 78 65 0.833333333333333 0.00518920645058279
TF TF:M01709 Factor: MAFA; motif: TCAGCAN 0.00962929493089965 6391 18 14 0.777777777777778 0.00219058050383352
TF TF:M04148_1 Factor: TFAP2A; motif: NGCCCYNNGGGCN; match class: 1 0.00962929493089965 9613 111 74 0.666666666666667 0.0076979090814522
TF TF:M04934_1 Factor: TR4; motif: ACCCCGS; match class: 1 0.00962929493089965 15478 98 91 0.928571428571429 0.00587931257268381
TF TF:M10045 Factor: RAR-gamma; motif: RGGTCANNNTGNCCNNNN 0.00971079181083861 7399 72 43 0.597222222222222 0.00581159616164347
TF TF:M09599_1 Factor: COUP-TF2; motif: NARAGGTCARRGN; match class: 1 0.00971079181083861 159 12 3 0.25 0.0188679245283019
TF TF:M03558 Factor: P73; motif: GNNNRRRCNTGCMNNTSASN 0.00986022498724205 4679 107 43 0.401869158878505 0.00918999786279119
TF TF:M08870_1 Factor: DEC1; motif: NCNCACRTGNSC; match class: 1 0.0101295601278834 2440 62 19 0.306451612903226 0.00778688524590164
TF TF:M11829_1 Factor: LRH-1; motif: NTCAAGGTCAN; match class: 1 0.0101503442248722 165 12 3 0.25 0.0181818181818182
TF TF:M09761_1 Factor: EGR1; motif: NGNGKGGGYGGNGS; match class: 1 0.0101503442248722 1568 109 21 0.192660550458716 0.0133928571428571
TF TF:M00528_1 Factor: PPAR; motif: WASNRGGNCAAAGGTCA; match class: 1 0.0101503442248722 501 20 5 0.25 0.00998003992015968
TF TF:M11826_1 Factor: LRH-1; motif: NTCAAGGTCRN; match class: 1 0.0101503442248722 166 12 3 0.25 0.0180722891566265
TF TF:M06191 Factor: ZXDB; motif: NGGGGTC 0.0102333070830937 5926 90 44 0.488888888888889 0.00742490718866014
TF TF:M06190 Factor: ZXDA; motif: NGGGGTC 0.0102333070830937 5926 90 44 0.488888888888889 0.00742490718866014
TF TF:M04148 Factor: TFAP2A; motif: NGCCCYNNGGGCN 0.0102333070830937 10040 111 76 0.684684684684685 0.00756972111553785
TF TF:M11352_1 Factor: MafG; motif: TGCTGACNNN; match class: 1 0.0102333070830937 132 15 3 0.2 0.0227272727272727
TF TF:M04152 Factor: TFAP2C; motif: NGCCCNNRGGCA 0.0106341601191641 7738 109 62 0.568807339449541 0.00801240630653916
TF TF:M02089_1 Factor: E2F-3; motif: GGCGGGN; match class: 1 0.0108003139040476 9362 111 72 0.648648648648649 0.00769066438795129
TF TF:M04146_1 Factor: TFAP2A; motif: YGCCCNNRGGCN; match class: 1 0.0108003139040476 3800 108 37 0.342592592592593 0.00973684210526316
TF TF:M09894 Factor: E2F-4; motif: SNGGGCGGGAANN 0.0108003139040476 16194 79 76 0.962025316455696 0.00469309620847227
TF TF:M10089_1 Factor: T-bet; motif: NNGNRGGTGTGRN; match class: 1 0.0108003139040476 1215 112 18 0.160714285714286 0.0148148148148148
TF TF:M02000_1 Factor: ERR3; motif: CAAGGTCA; match class: 1 0.0108003139040476 177 12 3 0.25 0.0169491525423729
TF TF:M05775_1 Factor: ZXDL; motif: NGGGGWS; match class: 1 0.0108003139040476 1704 88 19 0.215909090909091 0.011150234741784
TF TF:M09590 Factor: AP-2alpha; motif: NTNSCCTGRGGSNAN 0.0108003139040476 5211 90 40 0.444444444444444 0.00767606985223566
TF TF:M09890 Factor: ctcf; motif: YGGCCACCAGRKGGCRSYN 0.0108003139040476 8479 107 65 0.607476635514019 0.00766599834886189
TF TF:M00257 Factor: RREB-1; motif: CCCCAAACMMCCCC 0.0108003139040476 10516 96 69 0.71875 0.00656143020159757
TF TF:M09909_1 Factor: ER-alpha; motif: AGGTCASMNTGACCY; match class: 1 0.0108003139040476 2409 31 12 0.387096774193548 0.0049813200498132
TF TF:M00051_1 Factor: NF-kappaB; motif: GGGGATYCCC; match class: 1 0.0108003139040476 2797 118 32 0.271186440677966 0.0114408294601359
TF TF:M09833_1 Factor: RXRALPHA; motif: CNNTGRCCTYTNN; match class: 1 0.0108003139040476 987 41 9 0.219512195121951 0.00911854103343465
TF TF:M00531 Factor: nerf; motif: YRNCAGGAAGYRGSTBDS 0.0108003139040476 7615 111 62 0.558558558558559 0.00814182534471438
TF TF:M08906 Factor: TR4; motif: NCCCTGACCYB 0.0108003139040476 4530 118 45 0.38135593220339 0.00993377483443709
TF TF:M00727_1 Factor: SF-1; motif: TGACCTTG; match class: 1 0.0108003139040476 177 12 3 0.25 0.0169491525423729
TF TF:M08623 Factor: rfx3:SRF; motif: TRGCAACNNNNNCCNWATANGGN 0.0110559431300423 14645 72 66 0.916666666666667 0.00450665756230796
TF TF:M09671_1 Factor: VDR; motif: RRGGTCANNGRGKTCA; match class: 1 0.0113541799367797 2412 102 26 0.254901960784314 0.0107794361525705
TF TF:M01733 Factor: MZF-1; motif: TGGGGAR 0.0113541799367797 11391 64 51 0.796875 0.00447721885699236
TF TF:M09599 Factor: COUP-TF2; motif: NARAGGTCARRGN 0.0114218495307783 2243 48 15 0.3125 0.00668747213553277
TF TF:M01733_1 Factor: MZF-1; motif: TGGGGAR; match class: 1 0.0117669248320916 4931 83 36 0.433734939759036 0.00730075035489759
TF TF:M03921 Factor: SP3; motif: NCCACGCCCMC 0.011801405468578 3856 96 34 0.354166666666667 0.00881742738589212
TF TF:M12148_1 Factor: SP8; motif: NCCACGCCCMCN; match class: 1 0.011801405468578 421 95 9 0.0947368421052632 0.0213776722090261
TF TF:M12352 Factor: ZBTB44; motif: MACWGCAGS 0.0118242994855725 6614 32 21 0.65625 0.00317508315693982
TF TF:M07265 Factor: Nrf2; motif: NNTGACTCAGCAN 0.0118242994855725 4867 18 12 0.666666666666667 0.00246558454900349
TF TF:M11198 Factor: Myf-6; motif: NAACASCTGWCN 0.0118242994855725 442 25 5 0.2 0.0113122171945701
TF TF:M09835 Factor: ZNF189; motif: RSNNGGAACAGMR 0.0118335387609732 3351 76 26 0.342105263157895 0.00775887794688153
TF TF:M09898 Factor: Egr-2; motif: GNGRRNGWGKGGGNGGRG 0.0125964731452766 6484 109 54 0.495412844036697 0.00832819247378162
TF TF:M07041_1 Factor: HDAC1; motif: KGCARGGTC; match class: 1 0.0130836289959301 6354 84 43 0.511904761904762 0.00676739062008184
TF TF:M04224_1 Factor: NRL; motif: NNNNTGCTGAC; match class: 1 0.0130836289959301 653 18 5 0.277777777777778 0.00765696784073507
TF TF:M12140 Factor: Egr-1; motif: NNCRCCCMCGCNN 0.0130939266401632 5360 109 47 0.431192660550459 0.00876865671641791
TF TF:M03811 Factor: AP-2gamma; motif: GCCYNCRGSN 0.0132074797960719 8852 108 67 0.62037037037037 0.00756891098056936
TF TF:M09912_1 Factor: c-Ets-2; motif: NNNRGGAARNRRR; match class: 1 0.0132074797960719 2450 55 17 0.309090909090909 0.00693877551020408
TF TF:M00947 Factor: CP2/LBP-1c/LSF; motif: GCTGGNTNGNNCYNG 0.0132330324405827 8413 103 62 0.601941747572815 0.00736954712944253
TF TF:M04458_1 Factor: ESRRA; motif: CAAGGTCANNYSAAGGTCA; match class: 1 0.0133586241111882 4477 17 11 0.647058823529412 0.00245700245700246
TF TF:M04926 Factor: REST; motif: AAGGTGCT 0.0133586241111882 6325 10 9 0.9 0.00142292490118577
TF TF:M02111_1 Factor: NR1B2; motif: NTGACCY; match class: 1 0.0133586241111882 3323 107 33 0.308411214953271 0.00993078543484803
TF TF:M09973 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN 0.0134444857462914 10853 90 66 0.733333333333333 0.00608126785220676
TF TF:M00033_1 Factor: p300; motif: NNNGGGAGTNNNNS; match class: 1 0.0134444857462914 2588 82 23 0.280487804878049 0.00888717156105101
TF TF:M02089 Factor: E2F-3; motif: GGCGGGN 0.0134444857462914 13173 111 91 0.81981981981982 0.00690806953617247
TF TF:M07040_1 Factor: GKLF; motif: NNRRGRRNGNSNNN; match class: 1 0.0134444857462914 8156 84 51 0.607142857142857 0.00625306522805297
TF TF:M01036 Factor: COUPTF; motif: NNNNNTGACCYTTGNMCNYNGMN 0.0134444857462914 3807 58 23 0.396551724137931 0.0060415024954032
TF TF:M03811_1 Factor: AP-2gamma; motif: GCCYNCRGSN; match class: 1 0.0138403391741611 3812 91 32 0.351648351648352 0.00839454354669465
TF TF:M08964_1 Factor: NR1B1:RXR-ALPHA; motif: RRGGTCANNNNNRGGTCA; match class: 1 0.0139271804963586 1827 107 22 0.205607476635514 0.0120415982484948
TF TF:M01871 Factor: COE1; motif: NCYCWRGGGANYNN 0.0140874439504296 1650 118 22 0.186440677966102 0.0133333333333333
TF TF:M08960_1 Factor: PPARALPHA:RXR-ALPHA; motif: AWNTRGGTNAAAGGTCAN; match class: 1 0.0144205651664476 4739 60 27 0.45 0.00569740451572062
TF TF:M09603_1 Factor: Egr-1; motif: NNNNNGYGKGGGNGGGNN; match class: 1 0.0149919546697523 1317 109 18 0.165137614678899 0.0136674259681093
TF TF:M04152_1 Factor: TFAP2C; motif: NGCCCNNRGGCA; match class: 1 0.0150190467433317 5580 109 48 0.440366972477064 0.00860215053763441
TF TF:M11476_1 Factor: Tcfap2e; motif: TGCCCYNNGGCN; match class: 1 0.0152956414756969 244 27 4 0.148148148148148 0.0163934426229508
TF TF:M00054 Factor: NF-kappaB; motif: GGGAMTTYCC 0.015344073695974 2444 77 21 0.272727272727273 0.0085924713584288
TF TF:M03554 Factor: NF-1A; motif: NGCCARN 0.015344073695974 4908 14 10 0.714285714285714 0.00203748981255094
TF TF:M09659_1 Factor: PU.1; motif: NRAAAGAGGAAGTGARA; match class: 1 0.0157000564872119 179 102 6 0.0588235294117647 0.0335195530726257
TF TF:M00184 Factor: MyoD; motif: NNCACCTGNY 0.0159330961709092 1030 116 16 0.137931034482759 0.0155339805825243
TF TF:M09724 Factor: DATF1; motif: SNGGRRGCWGNGGG 0.0159330961709092 8400 108 64 0.592592592592593 0.00761904761904762
TF TF:M12352_1 Factor: ZBTB44; motif: MACWGCAGS; match class: 1 0.0160632533744516 1367 27 8 0.296296296296296 0.00585223116313094
TF TF:M11816_1 Factor: T3R-beta; motif: NRGGTCAAAGGTCAN; match class: 1 0.0161603151580174 4798 57 26 0.456140350877193 0.00541892455189662
TF TF:M12259 Factor: slug; motif: NRCAGGTGCR 0.0161603151580174 1780 76 17 0.223684210526316 0.00955056179775281
TF TF:M09727_1 Factor: GEMIN3; motif: NCWGGRARRGRGNGNG; match class: 1 0.0162550464814627 3210 117 34 0.290598290598291 0.0105919003115265
TF TF:M12354 Factor: ZNF37A; motif: CCYYGGCTCCNTSCCMN 0.0162632313269555 10961 33 28 0.848484848484849 0.00255451144968525
TF TF:M00225 Factor: STAT3; motif: NGNNATTTCCSGGAARTGNNN 0.0162632313269555 3188 8 6 0.75 0.00188205771643664
TF TF:M10432_1 Factor: MAZ; motif: GGGMGGGGS; match class: 1 0.0163830129923581 4365 109 40 0.36697247706422 0.00916380297823597
TF TF:M00225_1 Factor: STAT3; motif: NGNNATTTCCSGGAARTGNNN; match class: 1 0.0165097218278763 1922 8 5 0.625 0.00260145681581686
TF TF:M09602 Factor: ctcf; motif: NNNCCASYAGRKGGCRSYNN 0.01682092129951 7450 107 58 0.542056074766355 0.00778523489932886
TF TF:M12148 Factor: SP8; motif: NCCACGCCCMCN 0.0170366594116588 2907 114 31 0.271929824561404 0.0106639146886825
TF TF:M11742 Factor: COUP-TF1; motif: NRGGTCAAAGGTCAN 0.0173906885198446 1756 33 10 0.303030303030303 0.00569476082004556
TF TF:M00706 Factor: TFII-I; motif: RGAGGKAGG 0.0173906885198446 5714 52 27 0.519230769230769 0.00472523626181309
TF TF:M07348_1 Factor: AP-2alpha; motif: NSCCNCRGGSN; match class: 1 0.0173906885198446 2945 108 30 0.277777777777778 0.0101867572156197
TF TF:M01797 Factor: SIRT6; motif: AGATAARN 0.0173906885198446 1200 7 4 0.571428571428571 0.00333333333333333
TF TF:M04727_1 Factor: CTCF; motif: ACCAGGKGGC; match class: 1 0.0176251985346323 1579 102 19 0.186274509803922 0.0120329322355921
TF TF:M01109_1 Factor: SZF1-1; motif: CCAGGGTAWCAGCNG; match class: 1 0.0180736922447446 551 117 11 0.094017094017094 0.0199637023593466
TF TF:M09591 Factor: AP-2gamma; motif: NTGSCCTGRGGSNN 0.0183295062082309 8337 76 47 0.618421052631579 0.00563751949142377
TF TF:M00977_1 Factor: EBF; motif: KTCCCYWGRGA; match class: 1 0.0185949110536626 226 86 6 0.0697674418604651 0.0265486725663717
TF TF:M05438 Factor: Osx; motif: WGGGCGGGTS 0.0185949110536626 181 70 5 0.0714285714285714 0.0276243093922652
TF TF:M12160_1 Factor: KLF15; motif: RCCMCRCCCMCN; match class: 1 0.0185949110536626 8031 109 62 0.568807339449541 0.0077200846718964
TF TF:M03542_1 Factor: COUP-TF1; motif: TGACCTY; match class: 1 0.0187687253502385 869 16 5 0.3125 0.00575373993095512
TF TF:M08963_1 Factor: NR1B1; motif: RAGGTCA; match class: 1 0.0187687253502385 869 16 5 0.3125 0.00575373993095512
TF TF:M08968_1 Factor: RXR-ALPHA; motif: RAGGTCA; match class: 1 0.0187687253502385 869 16 5 0.3125 0.00575373993095512
TF TF:M11476 Factor: Tcfap2e; motif: TGCCCYNNGGCN 0.0190826922450238 2324 118 27 0.228813559322034 0.011617900172117
TF TF:M01972 Factor: EGR-1; motif: TGCGTGGGCGK 0.0190826922450238 5360 109 46 0.422018348623853 0.00858208955223881
TF TF:M00746_1 Factor: Elf-1; motif: RNWMBAGGAART; match class: 1 0.019366183789413 355 78 7 0.0897435897435897 0.0197183098591549
TF TF:M11073 Factor: DEC1; motif: GTCACGTGAC 0.019366183789413 6583 108 53 0.490740740740741 0.00805104055901565
TF TF:M12151_1 Factor: Sp1; motif: NWRGCCMCGCCCMCN; match class: 1 0.019366183789413 2548 114 28 0.245614035087719 0.010989010989011
TF TF:M10491 Factor: ZNF586; motif: CAGGCCYRGAGG 0.019366183789413 13875 109 92 0.844036697247706 0.00663063063063063
TF TF:M12150 Factor: SP9; motif: NCCACGCCCMCN 0.019366183789413 2353 111 26 0.234234234234234 0.0110497237569061
TF TF:M12179 Factor: BTEB3; motif: NRCCACGCCCMCN 0.0195482066783676 1350 111 18 0.162162162162162 0.0133333333333333
TF TF:M03893_1 Factor: WT1; motif: GNGGGGGCGGGG; match class: 1 0.0196816261671705 3980 109 37 0.339449541284404 0.0092964824120603
TF TF:M02110 Factor: NR1B1; motif: ANAGGTCANN 0.0202891171912175 2848 74 22 0.297297297297297 0.0077247191011236
TF TF:M07261 Factor: LKLF; motif: GGGGTGGKSN 0.0202891171912175 9774 91 61 0.67032967032967 0.00624104767751177
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.0206817592066545 10419 111 76 0.684684684684685 0.00729436606200211
TF TF:M03882 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC 0.0213612578236916 4474 11 8 0.727272727272727 0.00178810907465355
TF TF:M07051 Factor: NF-1B; motif: CTGGCASGV 0.0214846908871086 3915 96 33 0.34375 0.00842911877394636
TF TF:M03923 Factor: SP8; motif: RCCACGCCCMCY 0.0217559838612219 2843 114 30 0.263157894736842 0.0105522335561027
TF TF:M04797_1 Factor: Egr-1; motif: CCGCCCMCG; match class: 1 0.0217559838612219 1565 114 20 0.175438596491228 0.012779552715655
TF TF:M07325 Factor: MaFA; motif: TCTGCTGASCNN 0.0222836727860512 3990 12 8 0.666666666666667 0.00200501253132832
TF TF:M09671 Factor: VDR; motif: RRGGTCANNGRGKTCA 0.0222836727860512 8106 57 36 0.631578947368421 0.00444115470022206
TF TF:M08304_1 Factor: FOXO1A:ETV7; motif: NWMAACAGGAMNNNCTTCCNN; match class: 1 0.0223732653436729 7620 23 17 0.739130434782609 0.00223097112860892
TF TF:M09807 Factor: GATA2; motif: NNCTTATCTNN 0.0223870659850804 1347 7 4 0.571428571428571 0.00296956198960653
TF TF:M10038 Factor: PPARgamma; motif: NWSTRGGKSARAGGKCA 0.0228854443120655 6667 58 32 0.551724137931034 0.0047997600119994
TF TF:M06202 Factor: ZXDB; motif: NAGGGTG 0.023047616597598 7463 102 55 0.53921568627451 0.00736969047300013
TF TF:M12152_1 Factor: Sp1; motif: NWRGCCACGCCCMCN; match class: 1 0.023047616597598 2859 114 30 0.263157894736842 0.0104931794333683
TF TF:M06203 Factor: ZXDA; motif: NAGGGTG 0.023047616597598 7463 102 55 0.53921568627451 0.00736969047300013
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.023047616597598 10281 111 75 0.675675675675676 0.0072950102130143
TF TF:M12257 Factor: SNA; motif: NRCAGGTGCR 0.023173641648729 2267 64 17 0.265625 0.00749889722099691
TF TF:M12261 Factor: slug; motif: NRCAGGTGCR 0.023173641648729 2267 64 17 0.265625 0.00749889722099691
TF TF:M00158 Factor: COUP-TF,; motif: TGAMCTTTGMMCYT 0.0232142602801242 2215 77 19 0.246753246753247 0.00857787810383747
TF TF:M08016 Factor: COUP-TF1; motif: NARAGGTCANNNG 0.0232437479921947 1369 17 6 0.352941176470588 0.0043827611395179
TF TF:M07387 Factor: LRF; motif: NGKGGGTSNCN 0.0232437479921947 5232 95 40 0.421052631578947 0.00764525993883792
TF TF:M00033 Factor: p300; motif: NNNGGGAGTNNNNS 0.0236213455955842 8577 64 41 0.640625 0.00478022618631223
TF TF:M08878_1 Factor: EGR; motif: CGCCCCCGCNN; match class: 1 0.0236247631002996 3224 116 33 0.28448275862069 0.0102357320099256
TF TF:M00698 Factor: HEB; motif: RCCWGCTG 0.0240921983648766 2787 77 22 0.285714285714286 0.00789379260853965
TF TF:M11827 Factor: LRH-1; motif: YGACCTTGNNNCAAGGTCR 0.0241906462120353 2196 55 15 0.272727272727273 0.00683060109289617
TF TF:M04873_1 Factor: ERR1; motif: NTGACCTTGRNN; match class: 1 0.0244030456851759 310 12 3 0.25 0.00967741935483871
TF TF:M11477 Factor: AP-2beta; motif: NSCCYNRGGSN 0.0244030456851759 8252 112 64 0.571428571428571 0.00775569558894813
TF TF:M00531_1 Factor: nerf; motif: YRNCAGGAAGYRGSTBDS; match class: 1 0.0244276594615074 1902 76 17 0.223684210526316 0.00893796004206099
TF TF:M09977_1 Factor: Lyl-1; motif: NCAKCTGYTNYCNN; match class: 1 0.0247071039125502 7633 77 44 0.571428571428571 0.00576444386217739
TF TF:M00800 Factor: AP-2; motif: GSCCSCRGGCNRNRNN 0.0247339288644611 9119 70 46 0.657142857142857 0.00504441276455752
TF TF:M10105 Factor: USF1; motif: NGTCACGTGRNS 0.0247339288644611 2407 100 24 0.24 0.00997091815538014
TF TF:M08402 Factor: POU2F1:PEA3; motif: ACCGGATATGCAN 0.0247339288644611 8519 46 31 0.673913043478261 0.00363892475642681
TF TF:M07039 Factor: ETF; motif: CCCCGCCCCYN 0.0249059496403269 16384 111 104 0.936936936936937 0.00634765625
TF TF:M07407_1 Factor: THAP1; motif: YTGCCCNNA; match class: 1 0.0249570934994827 4197 67 26 0.388059701492537 0.00619490111984751
TF TF:M04881 Factor: ER-alpha; motif: ARGSTGACC 0.0249570934994827 3973 74 27 0.364864864864865 0.00679587213692424
TF TF:M10013 Factor: LXR-alpha; motif: NNRRGGTYACTNNAGGNCA 0.0257127061115249 3171 36 14 0.388888888888889 0.00441501103752759
TF TF:M11818 Factor: T3R-beta; motif: NTGACCTYRNYRAGGTCAN 0.0261620561596631 11824 76 59 0.776315789473684 0.00498985115020298
TF TF:M01858 Factor: AP-2beta; motif: GCNNNGGSCNGVGGGN 0.0262264116330464 7418 110 58 0.527272727272727 0.00781881908870316
TF TF:M11814_1 Factor: T3R-beta; motif: NRGGTCAAAGGTCRN; match class: 1 0.0267591695123269 7275 61 35 0.573770491803279 0.00481099656357388
TF TF:M04896 Factor: AP-2alpha; motif: NNNGSCCTGRGGSN 0.0270830874446661 5780 96 43 0.447916666666667 0.00743944636678201
TF TF:M08302_1 Factor: FOXO1A:Net; motif: RWMAACAGGAAGTN; match class: 1 0.0271055359759816 2779 7 5 0.714285714285714 0.00179920834832674
TF TF:M08441_1 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG; match class: 1 0.0272699908904901 12761 91 73 0.802197802197802 0.00572055481545333
TF TF:M00701 Factor: SMAD3; motif: TGTCTGTCT 0.0276017255480849 4137 23 12 0.521739130434783 0.00290065264684554
TF TF:M09960 Factor: IRF-8; motif: NNAARRGGAASTGAAASTNN 0.0276084756558152 282 14 3 0.214285714285714 0.0106382978723404
TF TF:M07360 Factor: LRH-1; motif: NNNYCAAGGYCAN 0.0276272606094285 1554 16 6 0.375 0.00386100386100386
TF TF:M07387_1 Factor: LRF; motif: NGKGGGTSNCN; match class: 1 0.0276272606094285 1040 91 13 0.142857142857143 0.0125
TF TF:M12153 Factor: Sp3; motif: NGCCACGCCCMCN 0.0276272606094285 6205 111 51 0.459459459459459 0.00821917808219178
TF TF:M00272 Factor: p53; motif: NGRCWTGYCY 0.0276272606094285 4151 58 23 0.396551724137931 0.00554083353408817
TF TF:M11751 Factor: EAR2; motif: NRGGTCAAAGGTCRN 0.0276272606094285 1273 33 8 0.242424242424242 0.00628436763550668
TF TF:M00084_1 Factor: MZF-1; motif: KNGNKAGGGGNAA; match class: 1 0.0278309683093599 1683 87 17 0.195402298850575 0.0101010101010101
TF TF:M01104_1 Factor: MOVO-B; motif: GNGGGGG; match class: 1 0.0280037855293171 5626 110 47 0.427272727272727 0.00835407038748667
TF TF:M10106_1 Factor: VDR; motif: NRGGTCANNGRGKTCA; match class: 1 0.0283616892579262 1628 90 17 0.188888888888889 0.0104422604422604
TF TF:M10013_1 Factor: LXR-alpha; motif: NNRRGGTYACTNNAGGNCA; match class: 1 0.0286213675208053 342 12 3 0.25 0.0087719298245614
TF TF:M01857 Factor: AP-2alpha; motif: NGCCYSNNGSN 0.0287203287210943 9178 116 71 0.612068965517241 0.00773589017215079
TF TF:M08964 Factor: NR1B1:RXR-ALPHA; motif: RRGGTCANNNNNRGGTCA 0.0290093193271306 7003 107 54 0.504672897196262 0.00771098100813937
TF TF:M03997_1 Factor: GATA3; motif: NGATAANN; match class: 1 0.0290468073510947 635 7 3 0.428571428571429 0.0047244094488189
TF TF:M08918_1 Factor: GATA-3; motif: WGATAASN; match class: 1 0.0290468073510947 635 7 3 0.428571428571429 0.0047244094488189
TF TF:M07235 Factor: ZEB1; motif: NCWCACCTG 0.0290468073510947 1426 85 15 0.176470588235294 0.0105189340813464
TF TF:M12184 Factor: KLF14; motif: NRCCACGCCCMCN 0.0290468073510947 2532 114 27 0.236842105263158 0.0106635071090047
TF TF:M00761 Factor: p53; motif: RGRCAWGNCY 0.0291699239965224 2985 23 10 0.434782608695652 0.0033500837520938
TF TF:M07461 Factor: KLF; motif: GGGNGGGG 0.0292643889951401 8757 75 47 0.626666666666667 0.00536713486353774
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.0292643889951401 10430 91 63 0.692307692307692 0.00604026845637584
TF TF:M09667 Factor: TEF-3; motif: RCATTCCWGNNNN 0.0292643889951401 1034 116 15 0.129310344827586 0.0145067698259188
TF TF:M09610 Factor: ER-beta; motif: NRGGTCANKSTGACCTNN 0.0292643889951401 5822 64 31 0.484375 0.00532463071109584
TF TF:M08891 Factor: NFKAPPAB; motif: NNGGGANTTCCCN 0.0301806348646983 2110 116 24 0.206896551724138 0.0113744075829384
TF TF:M04726_1 Factor: REST; motif: GGACAGCKC; match class: 1 0.0301806348646983 1229 43 9 0.209302325581395 0.00732302685109845
TF TF:M01248 Factor: DAX1; motif: NNRNNNNAAGGTCANNNNNN 0.0302841891583656 823 12 4 0.333333333333333 0.00486026731470231
TF TF:M11830_1 Factor: LRH-1; motif: TGACCTTGRNYCAAGGTCA; match class: 1 0.0304917107555673 6100 82 39 0.475609756097561 0.00639344262295082
TF TF:M04146 Factor: TFAP2A; motif: YGCCCNNRGGCN 0.030495920482691 6552 109 52 0.477064220183486 0.00793650793650794
TF TF:M07602_1 Factor: CP2; motif: NNNNCCAGNCNN; match class: 1 0.030495920482691 4627 82 32 0.390243902439024 0.00691592824724444
TF TF:M08980 Factor: VDR:RXR-ALPHA; motif: NRGGTCANNNGGTTCNN 0.030495920482691 10442 78 55 0.705128205128205 0.00526719019344953
TF TF:M11897 Factor: Oct-2; motif: NNNATTATGCAN 0.0311644252859002 4836 7 6 0.857142857142857 0.00124069478908189
TF TF:M01172_1 Factor: PU.1; motif: NNNNYYYACTTCCTCTTTY; match class: 1 0.0312675669082034 580 28 5 0.178571428571429 0.00862068965517241
TF TF:M09870 Factor: MATH1; motif: RRCAGMTGG 0.0312675669082034 540 60 7 0.116666666666667 0.012962962962963
TF TF:M09630 Factor: IRF-4; motif: RRRGRGGAASTGARAS 0.0316368992939863 954 35 7 0.2 0.00733752620545073
TF TF:M04863 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG 0.0316475400097741 13618 91 76 0.835164835164835 0.005580848876487
TF TF:M01728 Factor: EAR2; motif: YGNNCTTTGNCCTK 0.0316475400097741 6372 13 10 0.769230769230769 0.00156936597614564
TF TF:M09603 Factor: Egr-1; motif: NNNNNGYGKGGGNGGGNN 0.0318042115633711 4627 109 40 0.36697247706422 0.00864491030905554
TF TF:M10038_1 Factor: PPARgamma; motif: NWSTRGGKSARAGGKCA; match class: 1 0.0321093681452794 1447 24 7 0.291666666666667 0.00483759502418798
TF TF:M07348 Factor: AP-2alpha; motif: NSCCNCRGGSN 0.0324681352942204 8047 110 61 0.554545454545455 0.00758046476947931
TF TF:M00646_1 Factor: LF-A1; motif: GGGSTCWR; match class: 1 0.0324681352942204 6320 32 19 0.59375 0.00300632911392405
TF TF:M01721_1 Factor: PUR1; motif: GGGNCAGNN; match class: 1 0.0325330991460582 3414 118 34 0.288135593220339 0.00995899238429994
TF TF:M00977 Factor: EBF; motif: KTCCCYWGRGA 0.0325330991460582 2283 25 9 0.36 0.00394218134034166
TF TF:M04831 Factor: ZEB1; motif: CAGGTGN 0.0325330991460582 8201 98 56 0.571428571428571 0.00682843555663943
TF TF:M01034_1 Factor: Ebox; motif: NCACSTGNCN; match class: 1 0.0327174320569433 879 49 8 0.163265306122449 0.00910125142207053
TF TF:M04149 Factor: TFAP2B; motif: NGCCCNNRGGCA 0.0327507716983375 2351 20 8 0.4 0.00340280731603573
TF TF:M10100 Factor: TFEA; motif: RGTCACGTGA 0.0329380307881886 6114 106 48 0.452830188679245 0.00785083415112856
TF TF:M11740 Factor: COUP-TF1; motif: NRGGTCAAAGGTCAN 0.032969079542139 898 96 12 0.125 0.0133630289532294
TF TF:M07474 Factor: Tbx20; motif: SGAGGTGTGAGGSGR 0.0337850650642731 3703 118 36 0.305084745762712 0.00972184715095868
TF TF:M08315 Factor: GCMa:FIGLA; motif: CASSTGNACCCGCAY 0.0337850650642731 977 55 9 0.163636363636364 0.00921187308085977
TF TF:M12181 Factor: BTEB3; motif: NRCCACGCCCMCN 0.0337884304271215 1597 111 19 0.171171171171171 0.0118973074514715
TF TF:M09903 Factor: elf5; motif: NNNANSAGGAAGTNN 0.0337884304271215 1243 28 7 0.25 0.00563153660498793
TF TF:M02036 Factor: WT1; motif: CGCCCCCNCN 0.0337884304271215 9767 118 75 0.635593220338983 0.0076789188082318
TF TF:M00341_1 Factor: GABP; motif: VCCGGAAGNGCR; match class: 1 0.0337884304271215 2318 114 25 0.219298245614035 0.0107851596203624
TF TF:M09973_1 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN; match class: 1 0.0337884304271215 6607 109 52 0.477064220183486 0.0078704404419555
TF TF:M08824 Factor: NET; motif: CMGGAARTR 0.033809072040422 1028 108 14 0.12962962962963 0.0136186770428016
TF TF:M11422_1 Factor: Erm; motif: NRCMGGAAGTN; match class: 1 0.0338545988482986 934 69 10 0.144927536231884 0.0107066381156317
TF TF:M12154 Factor: Sp3; motif: NGCCACGCCCMCN 0.0339743278206221 2190 114 24 0.210526315789474 0.010958904109589
TF TF:M11830 Factor: LRH-1; motif: TGACCTTGRNYCAAGGTCA 0.0341257289872766 7061 82 43 0.524390243902439 0.00608978898173063
TF TF:M09972 Factor: BTEB2; motif: WGGGTGKGGCNGGN 0.0341565878227893 9217 53 36 0.679245283018868 0.00390582619073451
TF TF:M02119 Factor: T3R-beta; motif: RRGNNANNNGAGGWCAN 0.0342975896740535 3585 34 14 0.411764705882353 0.00390516039051604
TF TF:M08955 Factor: FXR:RXR-ALPHA; motif: NRGGTCANRGGKN 0.0343918777942079 9729 36 27 0.75 0.00277520814061055
TF TF:M01100_1 Factor: LRF; motif: GGGGKYNNB; match class: 1 0.0346519767125031 2762 57 17 0.298245614035088 0.00615496017378711
TF TF:M12182 Factor: BTEB3; motif: NRCCACGCCCMCN 0.0349423204451709 1738 111 20 0.18018018018018 0.0115074798619102
TF TF:M09665 Factor: RBPJK; motif: SYGTGRGAANN 0.035553579709694 4441 118 41 0.347457627118644 0.00923215492006305
TF TF:M09590_1 Factor: AP-2alpha; motif: NTNSCCTGRGGSNAN; match class: 1 0.035553579709694 1008 65 10 0.153846153846154 0.00992063492063492
TF TF:M09726_1 Factor: GATAD2A; motif: CCTKTG; match class: 1 0.0356658559774034 9052 33 24 0.727272727272727 0.00265134776844896
TF TF:M00765 Factor: COUP; motif: TGACCTTTGACCC 0.0356658559774034 2693 116 28 0.241379310344828 0.0103973264017824
TF TF:M05775 Factor: ZXDL; motif: NGGGGWS 0.0356675723694684 6964 88 45 0.511363636363636 0.00646180356117174
TF TF:M06837 Factor: ZNF367; motif: TGCTRTNMYMC 0.0361041357443962 599 108 10 0.0925925925925926 0.01669449081803
TF TF:M10037 Factor: PPARalpha; motif: NWSTRGGNSAAAGGTCA 0.0361041357443962 6064 53 27 0.509433962264151 0.00445250659630607
TF TF:M08389 Factor: MGA:pitx1; motif: AGGTGNTAAKCCN 0.0364020227957558 431 24 4 0.166666666666667 0.00928074245939675
TF TF:M07277_1 Factor: BTEB2; motif: RGGGNGKGGN; match class: 1 0.0370472759828719 4149 111 37 0.333333333333333 0.0089178115208484
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.0373159152797887 14096 79 68 0.860759493670886 0.00482406356413167
TF TF:M10015 Factor: TR4; motif: GSTYMSRGGTCA 0.0373159152797887 2692 95 24 0.252631578947368 0.00891530460624071
TF TF:M12049 Factor: znf580; motif: NCTACCCYNNNMCTACCCT 0.0373159152797887 77 61 3 0.0491803278688525 0.038961038961039
TF TF:M10093 Factor: TEF-3; motif: RCATTCCWGNNNN 0.0374764643233861 1679 69 14 0.202898550724638 0.0083382966051221
TF TF:M03804 Factor: Tal-1; motif: CAGATGG 0.0374764643233861 5362 62 28 0.451612903225806 0.00522193211488251
TF TF:M00932_1 Factor: Sp1; motif: NNGGGGCGGGGNN; match class: 1 0.0377303523899576 6047 111 49 0.441441441441441 0.00810319166528857
TF TF:M09897 Factor: Egr-1; motif: NNNNGCGKGGGYGGNRN 0.0377303523899576 4244 109 37 0.339449541284404 0.0087181903864279
TF TF:M03802_1 Factor: SF-1; motif: NYCAAGGYCANNNN; match class: 1 0.0377303523899576 186 26 3 0.115384615384615 0.0161290322580645
TF TF:M00973_1 Factor: E2A; motif: CACCTGNY; match class: 1 0.0377303523899576 1041 64 10 0.15625 0.00960614793467819
TF TF:M00051 Factor: NF-kappaB; motif: GGGGATYCCC 0.0377303523899576 6413 90 43 0.477777777777778 0.00670513020427257
TF TF:M07351 Factor: COE1; motif: NNTCCCYTGRGNN 0.0377473528701352 1072 118 15 0.127118644067797 0.0139925373134328
TF TF:M00658_1 Factor: PU.1; motif: WGAGGAAG; match class: 1 0.0378542569095276 638 28 5 0.178571428571429 0.00783699059561128
TF TF:M03871 Factor: GLI; motif: MCVNNGACCACCCAV 0.0384177818319876 3331 37 14 0.378378378378378 0.00420294205944161
TF TF:M11753 Factor: EAR2; motif: NRGGTCAAAGGTCAN 0.0384798833321997 478 93 8 0.0860215053763441 0.0167364016736402
TF TF:M09817_1 Factor: PAX5; motif: RNGCGTGACCNN; match class: 1 0.0389161416570182 6170 96 44 0.458333333333333 0.00713128038897893
TF TF:M09805 Factor: FOXK1; motif: NNNGTAAACANGNN 0.0389777086188217 890 30 6 0.2 0.00674157303370787
TF TF:M00469_1 Factor: AP-2alpha; motif: GCCNNNRGS; match class: 1 0.0389777086188217 3334 114 32 0.280701754385965 0.00959808038392321
TF TF:M11482_1 Factor: AP-2gamma; motif: NSCCYNNRGSN; match class: 1 0.0389777086188217 2050 110 22 0.2 0.0107317073170732
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.0389777086188217 16244 91 85 0.934065934065934 0.00523270130509727
TF TF:M03835 Factor: Nrf2; motif: ACNRTGACTCAGCANWA 0.039022312252954 1562 18 6 0.333333333333333 0.00384122919334187
TF TF:M08398 Factor: POU2F1:Elk-1; motif: ACCGGAWATGCAW 0.039022312252954 7882 39 25 0.641025641025641 0.00317178381121543
TF TF:M08867 Factor: AP2; motif: GCCYGSGGSN 0.039022312252954 10054 97 64 0.65979381443299 0.00636562562164313
TF TF:M11258_1 Factor: AIBZIP; motif: NGMCACGTGGCN; match class: 1 0.039022312252954 172 61 4 0.0655737704918033 0.0232558139534884
TF TF:M01588_1 Factor: GKLF; motif: GCCMCRCCCNNN; match class: 1 0.039022312252954 3962 42 17 0.404761904761905 0.00429076224129228
TF TF:M09746 Factor: HNRPUL1; motif: NCNCAGN 0.0391136037380239 13720 64 55 0.859375 0.00400874635568513
TF TF:M07223 Factor: Pax-5; motif: NNRNKCAGYSRAGCRTGAC 0.0394500636200538 5600 52 25 0.480769230769231 0.00446428571428571
TF TF:M01595 Factor: STAT3; motif: NNTTCCRGGAANNNNN 0.0395218824443251 7736 17 13 0.764705882352941 0.00168045501551189
TF TF:M00189 Factor: AP-2; motif: MKCCCSCNGGCG 0.0397526391509588 10621 96 66 0.6875 0.00621410413332078
TF TF:M08487_1 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG; match class: 1 0.0397644149826181 8790 111 65 0.585585585585586 0.00739476678043231
TF TF:M07609_1 Factor: Ngn-2; motif: GNNNNNCAGMTGGNNN; match class: 1 0.0397850576570792 93 114 4 0.0350877192982456 0.043010752688172
TF TF:M08306 Factor: GCMa:Elf-1; motif: NNCGGAARTGCKGGT 0.0397850576570792 2776 73 20 0.273972602739726 0.00720461095100865
TF TF:M05467 Factor: Sall1; motif: NGGTCCKRGKRA 0.0397850576570792 4211 118 39 0.330508474576271 0.00926145808596533
TF TF:M01652 Factor: p53; motif: RGRCWWGYCYNGRCWWGYYY 0.0397850576570792 8083 78 45 0.576923076923077 0.00556723988618087
TF TF:M00982_1 Factor: KROX; motif: CCCGCCCCCRCCCC; match class: 1 0.0401638414350302 3518 109 32 0.293577981651376 0.00909607731665719
TF TF:M00341 Factor: GABP; motif: VCCGGAAGNGCR 0.0402622533216396 8224 85 49 0.576470588235294 0.00595817120622568
TF TF:M03867_1 Factor: c-Myc; motif: CACGTGGC; match class: 1 0.0402622533216396 2694 55 16 0.290909090909091 0.00593912397921307
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.0410588239677225 10357 110 73 0.663636363636364 0.00704837308100801
TF TF:M09900_1 Factor: Elf-1; motif: NNANCCGGAAGTGS; match class: 1 0.0414583438574549 1158 90 13 0.144444444444444 0.0112262521588946
TF TF:M01973_1 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC; match class: 1 0.0414583438574549 2398 67 17 0.253731343283582 0.00708924103419516
TF TF:M11204 Factor: TCFL4; motif: YNCAYGTGANN 0.0414814327810102 1345 28 7 0.25 0.00520446096654275
TF TF:M08568_1 Factor: ER71:E2A; motif: CASSTGNACCGGAWRYN; match class: 1 0.0421422782382849 15133 79 71 0.89873417721519 0.00469173329809027
TF TF:M08412_1 Factor: rfx3:SREBP-2; motif: ATGGYAACRTCACGTGAY; match class: 1 0.0432390046460892 4386 72 27 0.375 0.00615595075239398
TF TF:M12139_1 Factor: Egr-1; motif: NMCRCCCMCNCNN; match class: 1 0.0433927423042117 698 114 11 0.0964912280701754 0.0157593123209169
TF TF:M04756 Factor: sin3A; motif: TGTCCNNGGTGCTG 0.0433927423042117 14257 75 65 0.866666666666667 0.00455916391947815
TF TF:M07207 Factor: EBF1; motif: NTCCCCWGGGA 0.0433927423042117 483 56 6 0.107142857142857 0.0124223602484472
TF TF:M00088_1 Factor: Ik-3; motif: TNYTGGGAATACC; match class: 1 0.0433927423042117 1019 79 11 0.139240506329114 0.0107948969578018
TF TF:M00272_1 Factor: p53; motif: NGRCWTGYCY; match class: 1 0.0436797549439401 1167 17 5 0.294117647058824 0.00428449014567267
TF TF:M00034 Factor: p53; motif: GGACATGCCCGGGCATGTCY 0.0436797549439401 4510 67 26 0.388059701492537 0.0057649667405765
TF TF:M00973 Factor: E2A; motif: CACCTGNY 0.0436797549439401 5425 118 47 0.398305084745763 0.00866359447004608
TF TF:M09972_1 Factor: BTEB2; motif: WGGGTGKGGCNGGN; match class: 1 0.0436797549439401 3919 20 10 0.5 0.0025516713447308
TF TF:M09843 Factor: GABPBETA; motif: YCACTTCCKGN 0.0440102647283849 2553 108 25 0.231481481481481 0.00979240109674892
TF TF:M12185 Factor: BTEB4; motif: RCCACGCCCC 0.0440572373522095 2283 95 21 0.221052631578947 0.00919842312746386
TF TF:M00649_1 Factor: MAZ; motif: GGGGAGGG; match class: 1 0.0442990478067139 4166 83 29 0.349397590361446 0.00696111377820451
TF TF:M10016 Factor: Nur77; motif: AAAGGNCAN 0.0442990478067139 471 12 3 0.25 0.00636942675159236
TF TF:M08906_1 Factor: TR4; motif: NCCCTGACCYB; match class: 1 0.0442990478067139 743 108 11 0.101851851851852 0.0148048452220727
TF TF:M04721_1 Factor: STAT1; motif: NTTCCNGGA; match class: 1 0.0442990478067139 2635 12 6 0.5 0.00227703984819734
TF TF:M03568 Factor: TR4; motif: STGACCTTT 0.0442990478067139 471 12 3 0.25 0.00636942675159236
TF TF:M03802 Factor: SF-1; motif: NYCAAGGYCANNNN 0.0443013510742138 2108 96 20 0.208333333333333 0.0094876660341556
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.0448850115633749 8180 117 64 0.547008547008547 0.0078239608801956
TF TF:M12286 Factor: ZNF647; motif: NYAGGCCYAC 0.0448850115633749 6231 68 33 0.485294117647059 0.00529610014443909
TF TF:M03867 Factor: c-Myc; motif: CACGTGGC 0.0453298069782454 7391 63 35 0.555555555555556 0.00473548910837505
TF TF:M09890_1 Factor: ctcf; motif: YGGCCACCAGRKGGCRSYN; match class: 1 0.0458666870469408 2884 107 27 0.252336448598131 0.0093619972260749
TF TF:M02273 Factor: NURR1; motif: AAGGTCAC 0.0459522150923857 7668 59 34 0.576271186440678 0.004434011476265
TF TF:M08878 Factor: EGR; motif: CGCCCCCGCNN 0.0460567341372856 7483 111 57 0.513513513513513 0.00761726580248563
TF TF:M02036_1 Factor: WT1; motif: CGCCCCCNCN; match class: 1 0.0463030201377123 5290 109 43 0.394495412844037 0.00812854442344045
TF TF:M07247 Factor: CLOCK; motif: CCACSTGW 0.0463653262771311 1953 56 13 0.232142857142857 0.00665642601126472
TF TF:M12180 Factor: BTEB3; motif: NRCCACGCCCMCN 0.0463653262771311 2088 111 22 0.198198198198198 0.010536398467433
TF TF:M11073_1 Factor: DEC1; motif: GTCACGTGAC; match class: 1 0.0463653262771311 5291 106 42 0.39622641509434 0.00793800793800794
TF TF:M01288_1 Factor: NeuroD; motif: NNSCWGCTGNSY; match class: 1 0.0463653262771311 904 42 7 0.166666666666667 0.00774336283185841
TF TF:M07407 Factor: THAP1; motif: YTGCCCNNA 0.0465851985691163 11013 64 47 0.734375 0.00426768364659947
TF TF:M00037_1 Factor: NF-E2; motif: TGCTGAGTCAY; match class: 1 0.0465851985691163 1710 102 18 0.176470588235294 0.0105263157894737
TF TF:M11828_1 Factor: LRH-1; motif: TCAAGGTCRYGACCTTGR; match class: 1 0.0465851985691163 7853 32 21 0.65625 0.00267413727237998
TF TF:M00189_1 Factor: AP-2; motif: MKCCCSCNGGCG; match class: 1 0.0468748552090356 6093 96 43 0.447916666666667 0.00705727884457574
TF TF:M00115 Factor: Tax/CREB; motif: RTGACGCATAYCCCC 0.0469571162231535 9342 59 39 0.661016949152542 0.00417469492614001
TF TF:M07089_1 Factor: Fli-1; motif: RCAGGAAGTGR; match class: 1 0.0470269360728071 755 108 11 0.101851851851852 0.0145695364238411
TF TF:M10008_1 Factor: CSX; motif: NKRAGWGS; match class: 1 0.0470269360728071 3963 107 34 0.317757009345794 0.00857935907141055
TF TF:M08035_1 Factor: Rarb; motif: AGGTCANNYARAGGTCA; match class: 1 0.0474691650721764 1200 50 9 0.18 0.0075
TF TF:M03818 Factor: egr-3; motif: GTGGGY 0.0474691650721764 13384 67 56 0.835820895522388 0.00418410041841004
TF TF:M03796_1 Factor: MafA; motif: GGTCAGCAGH; match class: 1 0.047911674385667 681 18 4 0.222222222222222 0.00587371512481645
TF TF:M04811_1 Factor: RelA-p65; motif: BCWGGGRANNK; match class: 1 0.0485545844676174 1834 74 15 0.202702702702703 0.00817884405670665
TF TF:M08306_1 Factor: GCMa:Elf-1; motif: NNCGGAARTGCKGGT; match class: 1 0.0485545844676174 231 51 4 0.0784313725490196 0.0173160173160173
TF TF:M08952 Factor: NF-KAPPAB1; motif: NGGKRNTTYCCCN 0.0486260992239414 7763 110 58 0.527272727272727 0.00747133840010305
TF TF:M06608 Factor: ZNF486; motif: NGRGGCTTGGGA 0.0486467565833499 115 102 4 0.0392156862745098 0.0347826086956522
TF TF:M12149 Factor: SP9; motif: RCCACGCCCMCY 0.0489632934204374 2379 111 24 0.216216216216216 0.0100882723833544
TF TF:M07208 Factor: EGR1; motif: NCNCCGCCCCCGCN 0.0489632934204374 6183 111 49 0.441441441441441 0.0079249555232088
TF TF:M09761 Factor: EGR1; motif: NGNGKGGGYGGNGS 0.0495319819135387 5162 109 42 0.385321100917431 0.00813638124757846
TF TF:M09862_1 Factor: ZNF614; motif: NCYCWGCCYYNNN; match class: 1 0.0495798280451775 4193 55 21 0.381818181818182 0.00500834724540901
TF TF:M04926_1 Factor: REST; motif: AAGGTGCT; match class: 1 0.0497700465328608 1189 25 6 0.24 0.00504625735912532
TF TF:M12024 Factor: Tbx3; motif: NAGGTGTSAN 0.0498057363979203 4514 13 8 0.615384615384615 0.00177226406734603
TF TF:M01175_1 Factor: CKROX; motif: SCCCTCCCC; match class: 1 0.049842502180694 2679 116 27 0.232758620689655 0.0100783874580067
TF TF:M07353 Factor: E2A; motif: CAGNTGNN 0.049842502180694 2645 63 17 0.26984126984127 0.00642722117202268

pEpi40 transcription factor target enrichment of top program genes

TF enrichment of pEpi40
Possible regulators of activation of pEpi40 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.