pP10 program activity among Plasma cells

Activation of pP10
pP10 gene program activation in Plasma cells.
Gene program activation of pP10 by different cell subtypes
pP10 gene program activation among cells of different subtypes (Plasma cells).

pP10 top program genes

Top genes of pP10 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pP10 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pP10
pP10 gene-set enrichment summary using g-profiler webtool.

pP10 transcription factor target enrichment of top program genes

TF enrichment of pP10
TFs corrosponding to activation of pP10. (Left) pearson correlation of TF expression and gene expression program activatity in Plasma cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.