pM21 program activity among Myeloid cells

Activation of pM21
pM21 gene program activation in Myeloid cells.
Gene program activation of pM21 by different cell subtypes
pM21 gene program activation among cells of different subtypes (Myeloid cells).

pM21 top program genes

Top genes of pM21 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pM21 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pM21
pM21 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:7385 DTX3L-PARP9-STAT1 complex 0.000607611731082255 3 77 3 0.038961038961039 1
GO:BP GO:0045087 innate immune response 6.61350610150042e-46 998 126 66 0.523809523809524 0.0661322645290581
GO:BP GO:0098542 defense response to other organism 1.35990008321264e-45 1218 126 70 0.555555555555556 0.0574712643678161
GO:BP GO:0051707 response to other organism 7.09190756931387e-44 1592 126 75 0.595238095238095 0.0471105527638191
GO:BP GO:0043207 response to external biotic stimulus 7.09190756931387e-44 1594 126 75 0.595238095238095 0.0470514429109159
GO:BP GO:0051607 defense response to virus 1.41596848889619e-43 267 143 44 0.307692307692308 0.164794007490637
GO:BP GO:0140546 defense response to symbiont 1.41596848889619e-43 267 143 44 0.307692307692308 0.164794007490637
GO:BP GO:0009607 response to biotic stimulus 1.6910333176311e-43 1626 126 75 0.595238095238095 0.0461254612546125
GO:BP GO:0009615 response to virus 7.97093528455231e-42 364 126 45 0.357142857142857 0.123626373626374
GO:BP GO:0006955 immune response 1.89058296515989e-41 2311 126 83 0.658730158730159 0.0359151882302034
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 4.55133345973674e-40 2255 126 81 0.642857142857143 0.035920177383592
GO:BP GO:0006952 defense response 5.3618746633744e-40 1818 130 76 0.584615384615385 0.0418041804180418
GO:BP GO:0060337 type I interferon signaling pathway 2.69349243769442e-39 95 117 29 0.247863247863248 0.305263157894737
GO:BP GO:0071357 cellular response to type I interferon 3.54565326983405e-39 96 117 29 0.247863247863248 0.302083333333333
GO:BP GO:0034340 response to type I interferon 1.82032307573441e-38 101 117 29 0.247863247863248 0.287128712871287
GO:BP GO:0034097 response to cytokine 4.75883324254128e-37 1226 85 52 0.611764705882353 0.0424143556280587
GO:BP GO:0002376 immune system process 5.305590347357e-32 3278 126 85 0.674603174603175 0.0259304453935326
GO:BP GO:0019221 cytokine-mediated signaling pathway 5.85741883689537e-32 810 80 41 0.5125 0.0506172839506173
GO:BP GO:0071345 cellular response to cytokine stimulus 3.09550120990183e-31 1132 80 45 0.5625 0.0397526501766784
GO:BP GO:0034341 response to interferon-gamma 9.27795325201394e-29 196 123 29 0.235772357723577 0.147959183673469
GO:BP GO:0048525 negative regulation of viral process 4.20882889189609e-28 94 141 24 0.170212765957447 0.25531914893617
GO:BP GO:0009605 response to external stimulus 6.32510879820657e-28 2944 126 77 0.611111111111111 0.0261548913043478
GO:BP GO:0045071 negative regulation of viral genome replication 5.50334954654882e-27 54 141 20 0.141843971631206 0.37037037037037
GO:BP GO:0050792 regulation of viral process 8.41161372508513e-26 192 141 28 0.198581560283688 0.145833333333333
GO:BP GO:0002252 immune effector process 1.03941737639399e-25 1309 126 53 0.420634920634921 0.040488922841864
GO:BP GO:0043903 regulation of biological process involved in symbiotic interaction 3.8737873049691e-25 203 141 28 0.198581560283688 0.137931034482759
GO:BP GO:0019079 viral genome replication 1.95475048975117e-24 131 141 24 0.170212765957447 0.183206106870229
GO:BP GO:0045069 regulation of viral genome replication 2.54140112127626e-24 84 141 21 0.148936170212766 0.25
GO:BP GO:0071346 cellular response to interferon-gamma 5.37886517666107e-23 175 121 24 0.198347107438017 0.137142857142857
GO:BP GO:1903900 regulation of viral life cycle 8.91728361430496e-23 153 141 24 0.170212765957447 0.156862745098039
GO:BP GO:0016032 viral process 2.30992508715859e-22 942 144 46 0.319444444444444 0.0488322717622081
GO:BP GO:0044403 biological process involved in symbiotic interaction 3.27509077469282e-22 1001 144 47 0.326388888888889 0.046953046953047
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 5.84526715954709e-22 88 121 19 0.15702479338843 0.215909090909091
GO:BP GO:0006950 response to stress 1.62825367021619e-21 4170 144 89 0.618055555555556 0.0213429256594724
GO:BP GO:0019058 viral life cycle 6.96175080212804e-21 353 141 30 0.212765957446809 0.084985835694051
GO:BP GO:0071310 cellular response to organic substance 4.17782362227199e-19 2776 85 51 0.6 0.018371757925072
GO:BP GO:0010033 response to organic substance 1.42443078921624e-18 3412 80 53 0.6625 0.0155334114888628
GO:BP GO:0002831 regulation of response to biotic stimulus 5.12506945127702e-17 415 126 27 0.214285714285714 0.0650602409638554
GO:BP GO:0070887 cellular response to chemical stimulus 1.04212560786315e-16 3393 99 58 0.585858585858586 0.0170940170940171
GO:BP GO:0007166 cell surface receptor signaling pathway 2.47291507274337e-15 3210 80 48 0.6 0.0149532710280374
GO:BP GO:0042221 response to chemical 4.45760210232144e-13 4781 92 60 0.652173913043478 0.0125496758000418
GO:BP GO:0035455 response to interferon-alpha 5.06656957319892e-13 23 64 8 0.125 0.347826086956522
GO:BP GO:0031347 regulation of defense response 3.33990284939831e-12 704 91 24 0.263736263736264 0.0340909090909091
GO:BP GO:0045088 regulation of innate immune response 1.07348614442063e-11 309 104 18 0.173076923076923 0.058252427184466
GO:BP GO:0002682 regulation of immune system process 2.53935125352284e-11 1617 126 40 0.317460317460317 0.0247371675943105
GO:BP GO:0035456 response to interferon-beta 3.76707730303145e-11 30 133 9 0.0676691729323308 0.3
GO:BP GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 1.58147427442483e-10 75 121 11 0.0909090909090909 0.146666666666667
GO:BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 3.21967925278366e-10 80 121 11 0.0909090909090909 0.1375
GO:BP GO:0032101 regulation of response to external stimulus 3.36516887986572e-10 1051 91 26 0.285714285714286 0.0247383444338725
GO:BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 3.34098436684632e-09 99 121 11 0.0909090909090909 0.111111111111111
GO:BP GO:0050776 regulation of immune response 3.51639631096062e-09 996 121 28 0.231404958677686 0.0281124497991968
GO:BP GO:0050896 response to stimulus 2.03946668175658e-08 9407 144 111 0.770833333333333 0.0117997236100776
GO:BP GO:0007165 signal transduction 2.03946668175658e-08 6309 91 61 0.67032967032967 0.00966872721508955
GO:BP GO:0051716 cellular response to stimulus 2.12928651044164e-08 7781 92 69 0.75 0.0088677547873024
GO:BP GO:0023052 signaling 2.43970140517334e-08 6810 92 64 0.695652173913043 0.00939794419970631
GO:BP GO:0048584 positive regulation of response to stimulus 3.8365268931548e-08 2344 91 35 0.384615384615385 0.0149317406143345
GO:BP GO:0002833 positive regulation of response to biotic stimulus 5.49683202087822e-08 250 141 15 0.106382978723404 0.06
GO:BP GO:0080134 regulation of response to stress 5.61530559100244e-08 1443 91 27 0.296703296703297 0.0187110187110187
GO:BP GO:0050688 regulation of defense response to virus 7.30240208528482e-08 71 126 9 0.0714285714285714 0.126760563380282
GO:BP GO:0007154 cell communication 9.53924872119682e-08 6829 92 63 0.684782608695652 0.00922536242495241
GO:BP GO:0002230 positive regulation of defense response to virus by host 1.16861580070347e-07 33 126 7 0.0555555555555556 0.212121212121212
GO:BP GO:0045089 positive regulation of innate immune response 1.88447772617773e-07 216 104 12 0.115384615384615 0.0555555555555556
GO:BP GO:0032479 regulation of type I interferon production 4.12344683866573e-07 130 84 9 0.107142857142857 0.0692307692307692
GO:BP GO:0000209 protein polyubiquitination 4.27326229819866e-07 342 140 16 0.114285714285714 0.0467836257309941
GO:BP GO:0032606 type I interferon production 4.27326229819866e-07 131 84 9 0.107142857142857 0.0687022900763359
GO:BP GO:0050691 regulation of defense response to virus by host 7.68150528069536e-07 43 126 7 0.0555555555555556 0.162790697674419
GO:BP GO:0060700 regulation of ribonuclease activity 9.08206165432109e-07 9 67 4 0.0597014925373134 0.444444444444444
GO:BP GO:0002697 regulation of immune effector process 9.08206165432109e-07 461 126 17 0.134920634920635 0.0368763557483731
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.00846214528226e-06 174 121 11 0.0909090909090909 0.0632183908045977
GO:BP GO:0002684 positive regulation of immune system process 1.14544239175999e-06 1065 104 23 0.221153846153846 0.0215962441314554
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 1.55835105738675e-06 182 121 11 0.0909090909090909 0.0604395604395604
GO:BP GO:0050778 positive regulation of immune response 1.98357154476291e-06 753 104 19 0.182692307692308 0.0252324037184595
GO:BP GO:0002483 antigen processing and presentation of endogenous peptide antigen 2.45729711174912e-06 19 104 5 0.0480769230769231 0.263157894736842
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 2.58691028030365e-06 192 121 11 0.0909090909090909 0.0572916666666667
GO:BP GO:0032480 negative regulation of type I interferon production 2.59294769467707e-06 46 84 6 0.0714285714285714 0.130434782608696
GO:BP GO:0048583 regulation of response to stimulus 2.66997361488614e-06 4278 91 45 0.494505494505495 0.0105189340813464
GO:BP GO:0001817 regulation of cytokine production 3.22521936184553e-06 806 91 18 0.197802197802198 0.0223325062034739
GO:BP GO:0045824 negative regulation of innate immune response 3.67819795403632e-06 66 104 7 0.0673076923076923 0.106060606060606
GO:BP GO:0001816 cytokine production 6.25049338414656e-06 844 91 18 0.197802197802198 0.0213270142180095
GO:BP GO:0034612 response to tumor necrosis factor 7.9310902076062e-06 331 80 11 0.1375 0.0332326283987915
GO:BP GO:0060760 positive regulation of response to cytokine stimulus 8.92207230008351e-06 57 84 6 0.0714285714285714 0.105263157894737
GO:BP GO:0060759 regulation of response to cytokine stimulus 1.12758755576927e-05 197 84 9 0.107142857142857 0.0456852791878173
GO:BP GO:0006471 protein ADP-ribosylation 1.12758755576927e-05 36 141 6 0.0425531914893617 0.166666666666667
GO:BP GO:0019883 antigen processing and presentation of endogenous antigen 1.16799734118953e-05 26 104 5 0.0480769230769231 0.192307692307692
GO:BP GO:0051336 regulation of hydrolase activity 1.47082151264892e-05 1321 91 22 0.241758241758242 0.0166540499621499
GO:BP GO:0019882 antigen processing and presentation 1.63235586120204e-05 234 121 11 0.0909090909090909 0.047008547008547
GO:BP GO:0046719 regulation by virus of viral protein levels in host cell 1.70899777352589e-05 8 39 3 0.0769230769230769 0.375
GO:BP GO:0032020 ISG15-protein conjugation 2.03831984046492e-05 6 58 3 0.0517241379310345 0.5
GO:BP GO:0048519 negative regulation of biological process 2.39392996598272e-05 5757 85 49 0.576470588235294 0.00851137745353483
GO:BP GO:0061025 membrane fusion 2.81390916430741e-05 179 134 10 0.0746268656716418 0.0558659217877095
GO:BP GO:0071356 cellular response to tumor necrosis factor 3.01132162822277e-05 306 80 10 0.125 0.0326797385620915
GO:BP GO:0031349 positive regulation of defense response 3.53051550154978e-05 362 104 12 0.115384615384615 0.0331491712707182
GO:BP GO:0032069 regulation of nuclease activity 3.70335958322556e-05 22 67 4 0.0597014925373134 0.181818181818182
GO:BP GO:0032103 positive regulation of response to external stimulus 4.23778549686167e-05 513 104 14 0.134615384615385 0.0272904483430799
GO:BP GO:0140289 protein mono-ADP-ribosylation 4.91506137178473e-05 12 140 4 0.0285714285714286 0.333333333333333
GO:BP GO:0002832 negative regulation of response to biotic stimulus 5.22506824109161e-05 100 104 7 0.0673076923076923 0.07
GO:BP GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib 5.44252919924586e-05 5 104 3 0.0288461538461538 0.6
GO:BP GO:0035457 cellular response to interferon-alpha 8.30016378380922e-05 13 40 3 0.075 0.230769230769231
GO:BP GO:0050790 regulation of catalytic activity 9.10017848760616e-05 2545 86 29 0.337209302325581 0.0113948919449902
GO:BP GO:0032607 interferon-alpha production 9.28943660653085e-05 30 141 5 0.0354609929078014 0.166666666666667
GO:BP GO:0032647 regulation of interferon-alpha production 9.28943660653085e-05 30 141 5 0.0354609929078014 0.166666666666667
GO:BP GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane 9.43212997062539e-05 6 101 3 0.0297029702970297 0.5
GO:BP GO:0050777 negative regulation of immune response 9.52414766605768e-05 157 104 8 0.0769230769230769 0.0509554140127389
GO:BP GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib 0.000101028910808866 6 104 3 0.0288461538461538 0.5
GO:BP GO:0009617 response to bacterium 0.000112469486224702 743 91 15 0.164835164835165 0.0201884253028264
GO:BP GO:0051701 biological process involved in interaction with host 0.000120961747839942 221 130 10 0.0769230769230769 0.0452488687782805
GO:BP GO:0065009 regulation of molecular function 0.000134294739770239 3221 86 33 0.383720930232558 0.0102452654455138
GO:BP GO:0002221 pattern recognition receptor signaling pathway 0.000173873996513338 213 141 10 0.0709219858156028 0.0469483568075117
GO:BP GO:0006954 inflammatory response 0.000178015876501702 794 100 16 0.16 0.0201511335012594
GO:BP GO:0009967 positive regulation of signal transduction 0.000256888217894991 1598 91 22 0.241758241758242 0.0137672090112641
GO:BP GO:0001819 positive regulation of cytokine production 0.000302912718711211 452 141 14 0.099290780141844 0.0309734513274336
GO:BP GO:0052548 regulation of endopeptidase activity 0.000302912718711211 437 91 11 0.120879120879121 0.0251716247139588
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 0.000330670572862969 177 80 7 0.0875 0.0395480225988701
GO:BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 0.000364232281615712 185 141 9 0.0638297872340425 0.0486486486486487
GO:BP GO:0046135 pyrimidine nucleoside catabolic process 0.000365947519758162 22 126 4 0.0317460317460317 0.181818181818182
GO:BP GO:0035458 cellular response to interferon-beta 0.000369509237445307 21 133 4 0.0300751879699248 0.19047619047619
GO:BP GO:0001959 regulation of cytokine-mediated signaling pathway 0.000378055060587873 184 79 7 0.0886075949367089 0.0380434782608696
GO:BP GO:0010647 positive regulation of cell communication 0.000392364318067873 1777 91 23 0.252747252747253 0.0129431626336522
GO:BP GO:0023056 positive regulation of signaling 0.000407199583537343 1782 91 23 0.252747252747253 0.0129068462401796
GO:BP GO:0098586 cellular response to virus 0.000481930795029178 72 141 6 0.0425531914893617 0.0833333333333333
GO:BP GO:0016050 vesicle organization 0.000481930795029178 341 101 10 0.099009900990099 0.0293255131964809
GO:BP GO:1903901 negative regulation of viral life cycle 0.000481930795029178 26 115 4 0.0347826086956522 0.153846153846154
GO:BP GO:0052547 regulation of peptidase activity 0.000507137333326636 467 91 11 0.120879120879121 0.0235546038543897
GO:BP GO:0002718 regulation of cytokine production involved in immune response 0.000582554530636818 85 124 6 0.0483870967741935 0.0705882352941176
GO:BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 0.000620117699018922 251 141 10 0.0709219858156028 0.0398406374501992
GO:BP GO:0002683 negative regulation of immune system process 0.000658624973871824 420 104 11 0.105769230769231 0.0261904761904762
GO:BP GO:0032727 positive regulation of interferon-alpha production 0.000735590166149836 24 141 4 0.0283687943262411 0.166666666666667
GO:BP GO:0002720 positive regulation of cytokine production involved in immune response 0.000738689380434938 54 124 5 0.0403225806451613 0.0925925925925926
GO:BP GO:0032481 positive regulation of type I interferon production 0.000760848508813851 80 84 5 0.0595238095238095 0.0625
GO:BP GO:0023051 regulation of signaling 0.000783083757474033 3578 92 35 0.380434782608696 0.00978200111794299
GO:BP GO:0052126 movement in host environment 0.000900701666402316 177 130 8 0.0615384615384615 0.0451977401129944
GO:BP GO:0060334 regulation of interferon-gamma-mediated signaling pathway 0.000923347982380853 26 48 3 0.0625 0.115384615384615
GO:BP GO:0060330 regulation of response to interferon-gamma 0.000923347982380853 26 48 3 0.0625 0.115384615384615
GO:BP GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 0.000945791852893953 13 101 3 0.0297029702970297 0.230769230769231
GO:BP GO:0070555 response to interleukin-1 0.000945791852893953 215 80 7 0.0875 0.0325581395348837
GO:BP GO:0002367 cytokine production involved in immune response 0.000945791852893953 94 124 6 0.0483870967741935 0.0638297872340425
GO:BP GO:0001961 positive regulation of cytokine-mediated signaling pathway 0.000945791852893953 50 72 4 0.0555555555555556 0.08
GO:BP GO:0002475 antigen processing and presentation via MHC class Ib 0.0010248922848167 13 104 3 0.0288461538461538 0.230769230769231
GO:BP GO:0032648 regulation of interferon-beta production 0.00103988998271197 52 141 5 0.0354609929078014 0.0961538461538462
GO:BP GO:0016567 protein ubiquitination 0.00114956926413069 892 140 19 0.135714285714286 0.0213004484304933
GO:BP GO:0032446 protein modification by small protein conjugation 0.00117533954318843 973 140 20 0.142857142857143 0.0205549845837616
GO:BP GO:0032608 interferon-beta production 0.00122383817909537 54 141 5 0.0354609929078014 0.0925925925925926
GO:BP GO:0071222 cellular response to lipopolysaccharide 0.00130619718166177 200 91 7 0.0769230769230769 0.035
GO:BP GO:0001818 negative regulation of cytokine production 0.00132235530799131 381 104 10 0.0961538461538462 0.026246719160105
GO:BP GO:0046718 viral entry into host cell 0.00137412252638495 141 130 7 0.0538461538461538 0.049645390070922
GO:BP GO:0010646 regulation of cell communication 0.00143446944536411 3543 92 34 0.369565217391304 0.0095963872424499
GO:BP GO:0009164 nucleoside catabolic process 0.00149212320693245 33 126 4 0.0317460317460317 0.121212121212121
GO:BP GO:0002730 regulation of dendritic cell cytokine production 0.0016163399795508 13 124 3 0.0241935483870968 0.230769230769231
GO:BP GO:0071360 cellular response to exogenous dsRNA 0.00166563747506873 19 84 3 0.0357142857142857 0.157894736842105
GO:BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 0.00178038206215671 291 141 10 0.0709219858156028 0.0343642611683849
GO:BP GO:0009966 regulation of signal transduction 0.00181196728954858 3165 91 31 0.340659340659341 0.00979462875197472
GO:BP GO:0006213 pyrimidine nucleoside metabolic process 0.00181196728954858 35 126 4 0.0317460317460317 0.114285714285714
GO:BP GO:0071219 cellular response to molecule of bacterial origin 0.00184424692857634 214 91 7 0.0769230769230769 0.0327102803738318
GO:BP GO:0070647 protein modification by small protein conjugation or removal 0.00194354497659066 1184 140 22 0.157142857142857 0.0185810810810811
GO:BP GO:0002371 dendritic cell cytokine production 0.00194354497659066 14 124 3 0.0241935483870968 0.214285714285714
GO:BP GO:0071347 cellular response to interleukin-1 0.0020676879288766 185 144 8 0.0555555555555556 0.0432432432432432
GO:BP GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.00208488377106071 33 141 4 0.0283687943262411 0.121212121212121
GO:BP GO:0044409 entry into host 0.00211794030252244 154 130 7 0.0538461538461538 0.0454545454545455
GO:BP GO:0072529 pyrimidine-containing compound catabolic process 0.00233954043845056 38 126 4 0.0317460317460317 0.105263157894737
GO:BP GO:0006906 vesicle fusion 0.00235923902776645 108 132 6 0.0454545454545455 0.0555555555555556
GO:BP GO:0009968 negative regulation of signal transduction 0.00237016830080939 1364 28 9 0.321428571428571 0.00659824046920821
GO:BP GO:0071359 cellular response to dsRNA 0.00265444149122943 23 84 3 0.0357142857142857 0.130434782608696
GO:BP GO:0035563 positive regulation of chromatin binding 0.00266935024842316 14 142 3 0.0211267605633803 0.214285714285714
GO:BP GO:0032728 positive regulation of interferon-beta production 0.00279936680412306 36 141 4 0.0283687943262411 0.111111111111111
GO:BP GO:0007005 mitochondrion organization 0.00279936680412306 561 39 7 0.179487179487179 0.0124777183600713
GO:BP GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 0.00285035841885978 42 47 3 0.0638297872340425 0.0714285714285714
GO:BP GO:1901658 glycosyl compound catabolic process 0.00298100237720974 41 126 4 0.0317460317460317 0.0975609756097561
GO:BP GO:0090174 organelle membrane fusion 0.00299592238824125 114 132 6 0.0454545454545455 0.0526315789473684
GO:BP GO:0010522 regulation of calcium ion transport into cytosol 0.00309832741120827 106 91 5 0.0549450549450549 0.0471698113207547
GO:BP GO:0051241 negative regulation of multicellular organismal process 0.0030985903829046 1160 91 16 0.175824175824176 0.0137931034482759
GO:BP GO:0071216 cellular response to biotic stimulus 0.0030985903829046 238 91 7 0.0769230769230769 0.0294117647058824
GO:BP GO:0062207 regulation of pattern recognition receptor signaling pathway 0.00312284680379508 108 141 6 0.0425531914893617 0.0555555555555556
GO:BP GO:0032496 response to lipopolysaccharide 0.00316970944948925 338 65 7 0.107692307692308 0.0207100591715976
GO:BP GO:0044827 modulation by host of viral genome replication 0.00331738875810053 21 102 3 0.0294117647058824 0.142857142857143
GO:BP GO:0038061 NIK/NF-kappaB signaling 0.00334840715445067 194 80 6 0.075 0.0309278350515464
GO:BP GO:0034142 toll-like receptor 4 signaling pathway 0.00352053133589903 44 124 4 0.032258064516129 0.0909090909090909
GO:BP GO:0007259 receptor signaling pathway via JAK-STAT 0.0036872868475941 174 91 6 0.0659340659340659 0.0344827586206897
GO:BP GO:0006508 proteolysis 0.0036872868475941 1836 91 21 0.230769230769231 0.011437908496732
GO:BP GO:0010648 negative regulation of cell communication 0.00369042272935972 1468 28 9 0.321428571428571 0.0061307901907357
GO:BP GO:0002253 activation of immune response 0.00370668297931851 568 98 11 0.112244897959184 0.0193661971830986
GO:BP GO:0023057 negative regulation of signaling 0.00370893087963302 1471 28 9 0.321428571428571 0.00611828687967369
GO:BP GO:0007520 myoblast fusion 0.00380621708165299 42 134 4 0.0298507462686567 0.0952380952380952
GO:BP GO:0070663 regulation of leukocyte proliferation 0.00394721235762048 251 120 8 0.0666666666666667 0.0318725099601594
GO:BP GO:0072527 pyrimidine-containing compound metabolic process 0.0043737875602442 84 126 5 0.0396825396825397 0.0595238095238095
GO:BP GO:0002237 response to molecule of bacterial origin 0.00441796955953681 361 65 7 0.107692307692308 0.0193905817174515
GO:BP GO:0097696 receptor signaling pathway via STAT 0.004677315022142 184 91 6 0.0659340659340659 0.0326086956521739
GO:BP GO:1902036 regulation of hematopoietic stem cell differentiation 0.00474582724820539 75 80 4 0.05 0.0533333333333333
GO:BP GO:0062208 positive regulation of pattern recognition receptor signaling pathway 0.00477942141477093 43 141 4 0.0283687943262411 0.0930232558139535
GO:BP GO:0016553 base conversion or substitution editing 0.00477942141477093 20 126 3 0.0238095238095238 0.15
GO:BP GO:0070098 chemokine-mediated signaling pathway 0.0049476745048668 87 70 4 0.0571428571428571 0.0459770114942529
GO:BP GO:0010950 positive regulation of endopeptidase activity 0.00495703136033066 187 91 6 0.0659340659340659 0.0320855614973262
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.00496855903109591 1042 18 6 0.333333333333333 0.00575815738963532
GO:BP GO:0019439 aromatic compound catabolic process 0.00496855903109591 623 141 14 0.099290780141844 0.0224719101123595
GO:BP GO:0034656 nucleobase-containing small molecule catabolic process 0.00504046733494519 49 126 4 0.0317460317460317 0.0816326530612245
GO:BP GO:0000266 mitochondrial fission 0.00525737156679067 41 63 3 0.0476190476190476 0.0731707317073171
GO:BP GO:0008637 apoptotic mitochondrial changes 0.00536541968516712 126 21 3 0.142857142857143 0.0238095238095238
GO:BP GO:0010524 positive regulation of calcium ion transport into cytosol 0.00551826857686777 56 47 3 0.0638297872340425 0.0535714285714286
GO:BP GO:0044766 multi-organism transport 0.00589082744217206 66 41 3 0.0731707317073171 0.0454545454545455
GO:BP GO:1902579 multi-organism localization 0.00589082744217206 66 41 3 0.0731707317073171 0.0454545454545455
GO:BP GO:0034655 nucleobase-containing compound catabolic process 0.00640426941374343 567 141 13 0.0921985815602837 0.0229276895943563
GO:BP GO:0002703 regulation of leukocyte mediated immunity 0.00675935376917623 205 124 7 0.0564516129032258 0.0341463414634146
GO:BP GO:0031348 negative regulation of defense response 0.00677476080916288 246 104 7 0.0673076923076923 0.0284552845528455
GO:BP GO:1990869 cellular response to chemokine 0.00677476080916288 97 70 4 0.0571428571428571 0.0412371134020619
GO:BP GO:1990868 response to chemokine 0.00677476080916288 97 70 4 0.0571428571428571 0.0412371134020619
GO:BP GO:0002520 immune system development 0.00677476080916288 1020 91 14 0.153846153846154 0.0137254901960784
GO:BP GO:0002700 regulation of production of molecular mediator of immune response 0.00677476080916288 148 124 6 0.0483870967741935 0.0405405405405405
GO:BP GO:0019941 modification-dependent protein catabolic process 0.00677476080916288 662 29 6 0.206896551724138 0.00906344410876133
GO:BP GO:1901361 organic cyclic compound catabolic process 0.00698583690672019 651 141 14 0.099290780141844 0.021505376344086
GO:BP GO:0048518 positive regulation of biological process 0.007129703194716 6363 106 54 0.509433962264151 0.00848656294200849
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 0.0071964284799036 673 29 6 0.206896551724138 0.00891530460624071
GO:BP GO:0010952 positive regulation of peptidase activity 0.0071964284799036 205 91 6 0.0659340659340659 0.0292682926829268
GO:BP GO:0048872 homeostasis of number of cells 0.00720519699234576 261 12 3 0.25 0.0114942528735632
GO:BP GO:0002702 positive regulation of production of molecular mediator of immune response 0.00750918778671368 100 124 5 0.0403225806451613 0.05
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.00769704061878098 1037 91 14 0.153846153846154 0.0135004821600771
GO:BP GO:1901532 regulation of hematopoietic progenitor cell differentiation 0.00773369780950205 89 80 4 0.05 0.0449438202247191
GO:BP GO:0060218 hematopoietic stem cell differentiation 0.00773369780950205 89 80 4 0.05 0.0449438202247191
GO:BP GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 0.00773486070759078 81 88 4 0.0454545454545455 0.0493827160493827
GO:BP GO:0034121 regulation of toll-like receptor signaling pathway 0.00788786960618308 79 91 4 0.043956043956044 0.0506329113924051
GO:BP GO:0030593 neutrophil chemotaxis 0.00792703595859847 103 70 4 0.0571428571428571 0.0388349514563107
GO:BP GO:0002250 adaptive immune response 0.00810456135297294 689 121 13 0.107438016528926 0.0188679245283019
GO:BP GO:0002699 positive regulation of immune effector process 0.00810456135297294 215 124 7 0.0564516129032258 0.0325581395348837
GO:BP GO:0019730 antimicrobial humoral response 0.00811117891547228 145 88 5 0.0568181818181818 0.0344827586206897
GO:BP GO:0030097 hemopoiesis 0.0082756224134804 928 91 13 0.142857142857143 0.0140086206896552
GO:BP GO:0140253 cell-cell fusion 0.00828996507292287 55 134 4 0.0298507462686567 0.0727272727272727
GO:BP GO:0000768 syncytium formation by plasma membrane fusion 0.00828996507292287 55 134 4 0.0298507462686567 0.0727272727272727
GO:BP GO:0010629 negative regulation of gene expression 0.00849469919458517 1460 106 19 0.179245283018868 0.013013698630137
GO:BP GO:0048284 organelle fusion 0.00849469919458517 148 132 6 0.0454545454545455 0.0405405405405405
GO:BP GO:0002218 activation of innate immune response 0.00890577231645515 144 91 5 0.0549450549450549 0.0347222222222222
GO:BP GO:0035561 regulation of chromatin binding 0.00921877321296962 24 142 3 0.0211267605633803 0.125
GO:BP GO:0006949 syncytium formation 0.00921877321296962 57 134 4 0.0298507462686567 0.0701754385964912
GO:BP GO:0044788 modulation by host of viral process 0.00921877321296962 33 102 3 0.0294117647058824 0.0909090909090909
GO:BP GO:0048585 negative regulation of response to stimulus 0.00921877321296962 1733 28 9 0.321428571428571 0.0051933064050779
GO:BP GO:0002224 toll-like receptor signaling pathway 0.00921877321296962 161 124 6 0.0483870967741935 0.0372670807453416
GO:BP GO:0046700 heterocycle catabolic process 0.00930046199574774 602 141 13 0.0921985815602837 0.0215946843853821
GO:BP GO:0002819 regulation of adaptive immune response 0.00932023493232973 167 120 6 0.05 0.0359281437125748
GO:BP GO:0042592 homeostatic process 0.00938472800021208 1981 12 6 0.5 0.00302877334679455
GO:BP GO:0051279 regulation of release of sequestered calcium ion into cytosol 0.00940195806491978 85 91 4 0.043956043956044 0.0470588235294118
GO:BP GO:0035556 intracellular signal transduction 0.00940195806491978 2772 91 26 0.285714285714286 0.00937950937950938
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 0.00974458436501622 240 85 6 0.0705882352941176 0.025
GO:BP GO:1904427 positive regulation of calcium ion transmembrane transport 0.00975492890448954 74 47 3 0.0638297872340425 0.0405405405405405
GO:BP GO:0044270 cellular nitrogen compound catabolic process 0.00977481556511796 608 141 13 0.0921985815602837 0.0213815789473684
GO:BP GO:0045595 regulation of cell differentiation 0.00982681853058317 1679 6 4 0.666666666666667 0.00238237045860631
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 0.010098222436342 3241 117 35 0.299145299145299 0.0107991360691145
GO:BP GO:0002244 hematopoietic progenitor cell differentiation 0.010098222436342 172 80 5 0.0625 0.0290697674418605
GO:BP GO:0048878 chemical homeostasis 0.0103215472435808 1229 47 10 0.212765957446809 0.0081366965012205
GO:BP GO:0051603 proteolysis involved in cellular protein catabolic process 0.0104170754822993 750 29 6 0.206896551724138 0.008
GO:BP GO:0045596 negative regulation of cell differentiation 0.0104188477802371 697 6 3 0.5 0.00430416068866571
GO:BP GO:0048534 hematopoietic or lymphoid organ development 0.0104289866910722 966 91 13 0.142857142857143 0.0134575569358178
GO:BP GO:0039529 RIG-I signaling pathway 0.010475204132427 26 141 3 0.0212765957446809 0.115384615384615
GO:BP GO:0006900 vesicle budding from membrane 0.0105595186827448 107 76 4 0.0526315789473684 0.0373831775700935
GO:BP GO:0070665 positive regulation of leukocyte proliferation 0.0108660192355839 155 91 5 0.0549450549450549 0.032258064516129
GO:BP GO:0051239 regulation of multicellular organismal process 0.0108660192355839 2861 85 25 0.294117647058824 0.00873820342537574
GO:BP GO:0002429 immune response-activating cell surface receptor signaling pathway 0.0108884895662746 477 98 9 0.0918367346938776 0.0188679245283019
GO:BP GO:0002757 immune response-activating signal transduction 0.0108884895662746 477 98 9 0.0918367346938776 0.0188679245283019
GO:BP GO:0072507 divalent inorganic cation homeostasis 0.0110478371085169 516 91 9 0.0989010989010989 0.0174418604651163
GO:BP GO:0050851 antigen receptor-mediated signaling pathway 0.0114633098376896 323 91 7 0.0769230769230769 0.021671826625387
GO:BP GO:0070661 leukocyte proliferation 0.0117999952444129 325 91 7 0.0769230769230769 0.0215384615384615
GO:BP GO:0006915 apoptotic process 0.0121648147174474 1990 95 21 0.221052631578947 0.0105527638190955
GO:BP GO:0030162 regulation of proteolysis 0.0124643367367711 752 91 11 0.120879120879121 0.0146276595744681
GO:BP GO:1990266 neutrophil migration 0.0124692956768325 124 70 4 0.0571428571428571 0.032258064516129
GO:BP GO:1901224 positive regulation of NIK/NF-kappaB signaling 0.0129579327380541 68 59 3 0.0508474576271186 0.0441176470588235
GO:BP GO:0035567 non-canonical Wnt signaling pathway 0.013059199223079 151 27 3 0.111111111111111 0.0198675496688742
GO:BP GO:0071621 granulocyte chemotaxis 0.013059199223079 126 70 4 0.0571428571428571 0.0317460317460317
GO:BP GO:0060402 calcium ion transport into cytosol 0.0132431990811777 165 91 5 0.0549450549450549 0.0303030303030303
GO:BP GO:0050830 defense response to Gram-positive bacterium 0.0133649724856615 101 88 4 0.0454545454545455 0.0396039603960396
GO:BP GO:0050794 regulation of cellular process 0.013395583599964 11473 92 72 0.782608695652174 0.00627560359103983
GO:BP GO:0002705 positive regulation of leukocyte mediated immunity 0.0135912556183883 122 124 5 0.0403225806451613 0.040983606557377
GO:BP GO:0044257 cellular protein catabolic process 0.0138856954626843 813 29 6 0.206896551724138 0.00738007380073801
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 0.0139349465538653 512 135 11 0.0814814814814815 0.021484375
GO:BP GO:0043330 response to exogenous dsRNA 0.0140570060672776 50 84 3 0.0357142857142857 0.06
GO:BP GO:0032611 interleukin-1 beta production 0.0140570060672776 107 85 4 0.0470588235294118 0.0373831775700935
GO:BP GO:0002764 immune response-regulating signaling pathway 0.0142488129982292 515 135 11 0.0814814814814815 0.0213592233009709
GO:BP GO:2000736 regulation of stem cell differentiation 0.0144300573602463 115 80 4 0.05 0.0347826086956522
GO:BP GO:0048247 lymphocyte chemotaxis 0.0158088131148546 63 70 3 0.0428571428571429 0.0476190476190476
GO:BP GO:0002440 production of molecular mediator of immune response 0.0163031447185319 189 124 6 0.0483870967741935 0.0317460317460317
GO:BP GO:0042127 regulation of cell population proliferation 0.016357669110384 1774 95 19 0.2 0.0107102593010147
GO:BP GO:0099637 neurotransmitter receptor transport 0.0166267414128792 49 92 3 0.0326086956521739 0.0612244897959184
GO:BP GO:0051246 regulation of protein metabolic process 0.0166499903138657 2704 98 26 0.26530612244898 0.00961538461538462
GO:BP GO:0050852 T cell receptor signaling pathway 0.0170623127533524 203 80 5 0.0625 0.0246305418719212
GO:BP GO:0050789 regulation of biological process 0.0175841418853843 12091 93 75 0.806451612903226 0.00620296087999338
GO:BP GO:0070936 protein K48-linked ubiquitination 0.0179732249266403 61 77 3 0.038961038961039 0.0491803278688525
GO:BP GO:0043331 response to dsRNA 0.0179804357059627 56 84 3 0.0357142857142857 0.0535714285714286
GO:BP GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.0180893210790963 96 104 4 0.0384615384615385 0.0416666666666667
GO:BP GO:0016579 protein deubiquitination 0.0185714394175951 292 84 6 0.0714285714285714 0.0205479452054795
GO:BP GO:0002223 stimulatory C-type lectin receptor signaling pathway 0.0191186665237093 112 91 4 0.043956043956044 0.0357142857142857
GO:BP GO:0060401 cytosolic calcium ion transport 0.0192004847033772 186 91 5 0.0549450549450549 0.0268817204301075
GO:BP GO:0010628 positive regulation of gene expression 0.0194683847163943 1160 84 13 0.154761904761905 0.0112068965517241
GO:BP GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 0.0194683847163943 73 141 4 0.0283687943262411 0.0547945205479452
GO:BP GO:0002886 regulation of myeloid leukocyte mediated immunity 0.0194683847163943 54 91 3 0.032967032967033 0.0555555555555556
GO:BP GO:0033036 macromolecule localization 0.019577215453504 3218 102 30 0.294117647058824 0.00932256059664388
GO:BP GO:0051817 modulation of process of other organism involved in symbiotic interaction 0.019577215453504 102 102 4 0.0392156862745098 0.0392156862745098
GO:BP GO:0055074 calcium ion homeostasis 0.019577215453504 472 91 8 0.0879120879120879 0.0169491525423729
GO:BP GO:0002711 positive regulation of T cell mediated immunity 0.019577215453504 48 104 3 0.0288461538461538 0.0625
GO:BP GO:0002220 innate immune response activating cell surface receptor signaling pathway 0.0197993037114343 115 91 4 0.043956043956044 0.0347826086956522
GO:BP GO:0002821 positive regulation of adaptive immune response 0.0199773890669071 101 104 4 0.0384615384615385 0.0396039603960396
GO:BP GO:0002758 innate immune response-activating signal transduction 0.0201701195848689 116 91 4 0.043956043956044 0.0344827586206897
GO:BP GO:0051093 negative regulation of developmental process 0.0201701195848689 977 6 3 0.5 0.00307062436028659
GO:BP GO:0097530 granulocyte migration 0.0201701195848689 151 70 4 0.0571428571428571 0.0264900662251656
GO:BP GO:0008285 negative regulation of cell population proliferation 0.0203112871850616 790 95 11 0.115789473684211 0.0139240506329114
GO:BP GO:0006521 regulation of cellular amino acid metabolic process 0.0205009921018207 64 80 3 0.0375 0.046875
GO:BP GO:0051702 biological process involved in interaction with symbiont 0.020617276023941 96 111 4 0.036036036036036 0.0416666666666667
GO:BP GO:0015833 peptide transport 0.0207320836087905 1971 102 21 0.205882352941176 0.0106544901065449
GO:BP GO:0032612 interleukin-1 production 0.0208616171762396 126 85 4 0.0470588235294118 0.0317460317460317
GO:BP GO:1902750 negative regulation of cell cycle G2/M phase transition 0.0209628864320401 113 95 4 0.0421052631578947 0.0353982300884956
GO:BP GO:0050727 regulation of inflammatory response 0.0213989478332364 381 91 7 0.0769230769230769 0.0183727034120735
GO:BP GO:0002704 negative regulation of leukocyte mediated immunity 0.0215943582299139 51 104 3 0.0288461538461538 0.0588235294117647
GO:BP GO:0070646 protein modification by small protein removal 0.0218059747366598 310 84 6 0.0714285714285714 0.0193548387096774
GO:BP GO:0140029 exocytic process 0.0218059747366598 83 132 4 0.0303030303030303 0.0481927710843374
GO:BP GO:0012501 programmed cell death 0.0220055909868952 2143 95 21 0.221052631578947 0.00979934671021932
GO:BP GO:0044265 cellular macromolecule catabolic process 0.0220055909868952 1231 141 19 0.134751773049645 0.0154346060113729
GO:BP GO:0016192 vesicle-mediated transport 0.0221612021545253 2180 137 28 0.204379562043796 0.0128440366972477
GO:BP GO:0051651 maintenance of location in cell 0.0221612021545253 223 117 6 0.0512820512820513 0.0269058295964126
GO:BP GO:0008219 cell death 0.0221612021545253 2292 95 22 0.231578947368421 0.00959860383944154
GO:BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.0228216978179719 152 120 5 0.0416666666666667 0.0328947368421053
GO:BP GO:0051209 release of sequestered calcium ion into cytosol 0.0228236225931112 123 91 4 0.043956043956044 0.032520325203252
GO:BP GO:0009892 negative regulation of metabolic process 0.0229421187952566 3479 117 35 0.299145299145299 0.0100603621730382
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 0.0229421187952566 223 25 3 0.12 0.0134529147982063
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 0.0231196394908779 655 29 5 0.172413793103448 0.00763358778625954
GO:BP GO:0043086 negative regulation of catalytic activity 0.0231196394908779 851 91 11 0.120879120879121 0.0129259694477086
GO:BP GO:0072503 cellular divalent inorganic cation homeostasis 0.0231196394908779 497 91 8 0.0879120879120879 0.0160965794768612
GO:BP GO:0051283 negative regulation of sequestering of calcium ion 0.0231196394908779 124 91 4 0.043956043956044 0.032258064516129
GO:BP GO:0042886 amide transport 0.0233347639798838 2007 102 21 0.205882352941176 0.0104633781763827
GO:BP GO:0051282 regulation of sequestering of calcium ion 0.0239877462772661 126 91 4 0.043956043956044 0.0317460317460317
GO:BP GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic 0.0245812295850246 43 133 3 0.0225563909774436 0.0697674418604651
GO:BP GO:0030163 protein catabolic process 0.0247401254270974 974 29 6 0.206896551724138 0.00616016427104723
GO:BP GO:0030888 regulation of B cell proliferation 0.0248396244168403 63 91 3 0.032967032967033 0.0476190476190476
GO:BP GO:0030178 negative regulation of Wnt signaling pathway 0.0255412492506358 218 27 3 0.111111111111111 0.0137614678899083
GO:BP GO:0051928 positive regulation of calcium ion transport 0.0260158836583139 125 47 3 0.0638297872340425 0.024
GO:BP GO:0051208 sequestering of calcium ion 0.0260158836583139 130 91 4 0.043956043956044 0.0307692307692308
GO:BP GO:0061024 membrane organization 0.0262888255159758 973 143 16 0.111888111888112 0.0164439876670093
GO:BP GO:0008104 protein localization 0.0262888255159758 2770 86 23 0.267441860465116 0.00830324909747292
GO:BP GO:0050670 regulation of lymphocyte proliferation 0.0262888255159758 230 120 6 0.05 0.0260869565217391
GO:BP GO:0048522 positive regulation of cellular process 0.0266892030150372 5757 106 47 0.443396226415094 0.00816397429216606
GO:BP GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 0.0268550975687261 198 98 5 0.0510204081632653 0.0252525252525253
GO:BP GO:0032944 regulation of mononuclear cell proliferation 0.027060762092851 232 120 6 0.05 0.0258620689655172
GO:BP GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 0.02737745551599 66 92 3 0.0326086956521739 0.0454545454545455
GO:BP GO:0043462 regulation of ATPase activity 0.0274238162250587 80 76 3 0.0394736842105263 0.0375
GO:BP GO:0002548 monocyte chemotaxis 0.0275265369626817 67 91 3 0.032967032967033 0.0447761194029851
GO:BP GO:0042981 regulation of apoptotic process 0.0277456284200356 1549 9 4 0.444444444444444 0.0025823111684958
GO:BP GO:0071702 organic substance transport 0.0287255873447741 2766 102 26 0.254901960784314 0.0093998553868402
GO:BP GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 0.028914322693781 78 80 3 0.0375 0.0384615384615385
GO:BP GO:0050793 regulation of developmental process 0.0289983857943241 2605 6 4 0.666666666666667 0.00153550863723608
GO:BP GO:0045765 regulation of angiogenesis 0.0289983857943241 358 18 3 0.166666666666667 0.00837988826815642
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.0289983857943241 1082 97 13 0.134020618556701 0.0120147874306839
GO:BP GO:0015031 protein transport 0.0290346053697641 1929 102 20 0.196078431372549 0.0103680663556247
GO:BP GO:0043067 regulation of programmed cell death 0.0291533446808788 1582 9 4 0.444444444444444 0.00252844500632111
GO:BP GO:0097529 myeloid leukocyte migration 0.0291533446808788 221 91 5 0.0549450549450549 0.0226244343891403
GO:BP GO:0038093 Fc receptor signaling pathway 0.029498872217318 238 121 6 0.0495867768595041 0.0252100840336134
GO:BP GO:1901342 regulation of vasculature development 0.029498872217318 364 18 3 0.166666666666667 0.00824175824175824
GO:BP GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 0.0298652229623229 48 135 3 0.0222222222222222 0.0625
GO:BP GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 0.0298652229623229 71 91 3 0.032967032967033 0.0422535211267606
GO:BP GO:0065008 regulation of biological quality 0.0306734134998735 4131 14 8 0.571428571428571 0.00193657709997579
GO:BP GO:0033238 regulation of cellular amine metabolic process 0.0307432994709459 82 80 3 0.0375 0.0365853658536585
GO:BP GO:0030595 leukocyte chemotaxis 0.0307729344150705 227 91 5 0.0549450549450549 0.0220264317180617
GO:BP GO:0030099 myeloid cell differentiation 0.0308528045350106 428 91 7 0.0769230769230769 0.0163551401869159
GO:BP GO:0002698 negative regulation of immune effector process 0.0311225733413905 125 104 4 0.0384615384615385 0.032
GO:BP GO:0051851 modulation by host of symbiont process 0.031149500446077 65 102 3 0.0294117647058824 0.0461538461538462
GO:BP GO:0051345 positive regulation of hydrolase activity 0.031149500446077 783 91 10 0.10989010989011 0.0127713920817369
GO:BP GO:0044106 cellular amine metabolic process 0.031149500446077 163 80 4 0.05 0.0245398773006135
GO:BP GO:2001056 positive regulation of cysteine-type endopeptidase activity 0.0312688191110104 154 85 4 0.0470588235294118 0.025974025974026
GO:BP GO:0035821 modulation of process of other organism 0.0312688191110104 128 102 4 0.0392156862745098 0.03125
GO:BP GO:1901222 regulation of NIK/NF-kappaB signaling 0.0312688191110104 113 59 3 0.0508474576271186 0.0265486725663717
GO:BP GO:0007204 positive regulation of cytosolic calcium ion concentration 0.0312688191110104 325 91 6 0.0659340659340659 0.0184615384615385
GO:BP GO:0006401 RNA catabolic process 0.0313315138824498 424 141 9 0.0638297872340425 0.0212264150943396
GO:BP GO:0097553 calcium ion transmembrane import into cytosol 0.0316757310740357 145 91 4 0.043956043956044 0.0275862068965517
GO:BP GO:0031145 anaphase-promoting complex-dependent catabolic process 0.0316872575923203 85 80 3 0.0375 0.0352941176470588
GO:BP GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0.0316872575923203 95 139 4 0.0287769784172662 0.0421052631578947
GO:BP GO:0044093 positive regulation of molecular function 0.0316872575923203 1771 98 18 0.183673469387755 0.0101637492941841
GO:BP GO:0055065 metal ion homeostasis 0.0316872575923203 667 91 9 0.0989010989010989 0.0134932533733133
GO:BP GO:0043112 receptor metabolic process 0.0320117427585339 174 77 4 0.051948051948052 0.0229885057471264
GO:BP GO:0061013 regulation of mRNA catabolic process 0.0321286348228014 213 141 6 0.0425531914893617 0.028169014084507
GO:BP GO:0009308 amine metabolic process 0.0322302804397085 168 80 4 0.05 0.0238095238095238
GO:BP GO:0097194 execution phase of apoptosis 0.0322687197937695 96 72 3 0.0416666666666667 0.03125
GO:BP GO:0009116 nucleoside metabolic process 0.0323462963447996 107 126 4 0.0317460317460317 0.0373831775700935
GO:BP GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 0.0324202768428864 148 47 3 0.0638297872340425 0.0202702702702703
GO:BP GO:0034504 protein localization to nucleus 0.032556471628713 289 138 7 0.0507246376811594 0.0242214532871972
GO:BP GO:0060341 regulation of cellular localization 0.0326063636556126 851 48 7 0.145833333333333 0.0082256169212691
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 0.0327402763852009 159 135 5 0.037037037037037 0.0314465408805031
GO:BP GO:0060255 regulation of macromolecule metabolic process 0.0327708415947404 6603 86 43 0.5 0.00651219142813872
GO:BP GO:0010941 regulation of cell death 0.033085587840949 1720 9 4 0.444444444444444 0.00232558139534884
GO:BP GO:1904064 positive regulation of cation transmembrane transport 0.033085587840949 150 47 3 0.0638297872340425 0.02
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0333877699363761 2541 65 17 0.261538461538462 0.00669027941755215
GO:BP GO:0097190 apoptotic signaling pathway 0.03365511938105 600 85 8 0.0941176470588235 0.0133333333333333
GO:BP GO:0050801 ion homeostasis 0.0340512181366347 808 91 10 0.10989010989011 0.0123762376237624
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0340512181366347 253 55 4 0.0727272727272727 0.0158102766798419
GO:BP GO:0044248 cellular catabolic process 0.0342654710789028 2347 141 29 0.205673758865248 0.0123561994034938
GO:BP GO:0048523 negative regulation of cellular process 0.0346455494395674 5139 85 35 0.411764705882353 0.00681066355322047
GO:BP GO:0001666 response to hypoxia 0.035062267473739 367 85 6 0.0705882352941176 0.0163487738419619
GO:BP GO:0042267 natural killer cell mediated cytotoxicity 0.0351825325266614 62 118 3 0.0254237288135593 0.0483870967741935
GO:BP GO:0044092 negative regulation of molecular function 0.0351834233575577 1219 91 13 0.142857142857143 0.0106644790812141
GO:BP GO:0002009 morphogenesis of an epithelium 0.0357275351267642 560 26 4 0.153846153846154 0.00714285714285714
GO:BP GO:0001525 angiogenesis 0.0359570848178843 617 37 5 0.135135135135135 0.00810372771474878
GO:BP GO:2000779 regulation of double-strand break repair 0.0359570848178843 87 85 3 0.0352941176470588 0.0344827586206897
GO:BP GO:1903169 regulation of calcium ion transmembrane transport 0.0359570848178843 158 47 3 0.0638297872340425 0.0189873417721519
GO:BP GO:0032760 positive regulation of tumor necrosis factor production 0.0359570848178843 88 84 3 0.0357142857142857 0.0340909090909091
GO:BP GO:0032102 negative regulation of response to external stimulus 0.0361386964350436 406 78 6 0.0769230769230769 0.0147783251231527
GO:BP GO:0051248 negative regulation of protein metabolic process 0.0368177047909823 1151 97 13 0.134020618556701 0.0112945264986968
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.0368177047909823 3483 106 31 0.292452830188679 0.00890037324145851
GO:BP GO:0006874 cellular calcium ion homeostasis 0.0370442170246945 460 91 7 0.0769230769230769 0.0152173913043478
GO:BP GO:2000026 regulation of multicellular organismal development 0.0370442170246945 1447 6 3 0.5 0.00207325501036628
GO:BP GO:0009888 tissue development 0.0372746433475759 2107 8 4 0.5 0.0018984337921215
GO:BP GO:0006820 anion transport 0.0372951283031747 2889 102 26 0.254901960784314 0.00899965385946694
GO:BP GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 0.0373389429847414 91 84 3 0.0357142857142857 0.032967032967033
GO:BP GO:0010466 negative regulation of peptidase activity 0.0373648909317498 267 55 4 0.0727272727272727 0.0149812734082397
GO:BP GO:0002228 natural killer cell mediated immunity 0.0374348409544926 65 118 3 0.0254237288135593 0.0461538461538462
GO:BP GO:0002709 regulation of T cell mediated immunity 0.0377287523769019 74 104 3 0.0288461538461538 0.0405405405405405
GO:BP GO:0043085 positive regulation of catalytic activity 0.0380558680699972 1418 98 15 0.153061224489796 0.0105782792665726
GO:BP GO:0045184 establishment of protein localization 0.0380558680699972 2035 102 20 0.196078431372549 0.00982800982800983
GO:BP GO:0036293 response to decreased oxygen levels 0.0382947095681582 382 85 6 0.0705882352941176 0.0157068062827225
GO:BP GO:0071705 nitrogen compound transport 0.0385106988327389 2322 102 22 0.215686274509804 0.00947459086993971
GO:BP GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 0.0385439812686909 92 85 3 0.0352941176470588 0.0326086956521739
GO:BP GO:0008283 cell population proliferation 0.0394538176871928 2054 95 19 0.2 0.00925024342745862
GO:BP GO:0051480 regulation of cytosolic calcium ion concentration 0.0394538176871928 360 91 6 0.0659340659340659 0.0166666666666667
GO:BP GO:0010468 regulation of gene expression 0.0394538176871928 5196 97 39 0.402061855670103 0.00750577367205543
GO:BP GO:0042509 regulation of tyrosine phosphorylation of STAT protein 0.0394975737545814 87 91 3 0.032967032967033 0.0344827586206897
GO:BP GO:1902531 regulation of intracellular signal transduction 0.0395903589501495 1842 91 17 0.186813186813187 0.00922909880564604
GO:BP GO:0042157 lipoprotein metabolic process 0.0399030761725486 136 111 4 0.036036036036036 0.0294117647058824
GO:BP GO:0006875 cellular metal ion homeostasis 0.0399030761725486 593 91 8 0.0879120879120879 0.0134907251264755
GO:BP GO:0070498 interleukin-1-mediated signaling pathway 0.0399030761725486 105 144 4 0.0277777777777778 0.0380952380952381
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 0.0399030761725486 1202 37 7 0.189189189189189 0.00582362728785358
GO:BP GO:0051924 regulation of calcium ion transport 0.0399030761725486 259 91 5 0.0549450549450549 0.0193050193050193
GO:BP GO:0038095 Fc-epsilon receptor signaling pathway 0.0402196760009331 167 91 4 0.043956043956044 0.0239520958083832
GO:BP GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 0.0405812182854595 123 124 4 0.032258064516129 0.032520325203252
GO:BP GO:0007260 tyrosine phosphorylation of STAT protein 0.0406151718894078 89 91 3 0.032967032967033 0.0337078651685393
GO:BP GO:0072676 lymphocyte migration 0.0413394578927084 117 70 3 0.0428571428571429 0.0256410256410256
GO:BP GO:0065007 biological regulation 0.0413826614271488 12809 93 76 0.817204301075269 0.00593332812865954
GO:BP GO:0006959 humoral immune response 0.0426954661833603 384 88 6 0.0681818181818182 0.015625
GO:BP GO:0010959 regulation of metal ion transport 0.0434592394756691 268 91 5 0.0549450549450549 0.0186567164179104
GO:BP GO:0051100 negative regulation of binding 0.0438800161874172 163 52 3 0.0576923076923077 0.0184049079754601
GO:BP GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 0.0441819917996985 63 135 3 0.0222222222222222 0.0476190476190476
GO:BP GO:0014902 myotube differentiation 0.044791957407179 119 134 4 0.0298507462686567 0.0336134453781513
GO:BP GO:0045862 positive regulation of proteolysis 0.0452970276995125 378 91 6 0.0659340659340659 0.0158730158730159
GO:BP GO:0032651 regulation of interleukin-1 beta production 0.0460684077881814 102 85 3 0.0352941176470588 0.0294117647058824
GO:BP GO:0070482 response to oxygen levels 0.0461963086969165 408 85 6 0.0705882352941176 0.0147058823529412
GO:BP GO:0006520 cellular amino acid metabolic process 0.04642330414943 341 26 3 0.115384615384615 0.00879765395894428
GO:BP GO:0009057 macromolecule catabolic process 0.0465479134443224 1468 32 7 0.21875 0.00476839237057221
GO:BP GO:1901564 organonitrogen compound metabolic process 0.0472298653367356 6792 112 54 0.482142857142857 0.00795053003533569
GO:BP GO:1901657 glycosyl compound metabolic process 0.0472301407583929 130 126 4 0.0317460317460317 0.0307692307692308
GO:BP GO:0055080 cation homeostasis 0.0472504104558002 750 91 9 0.0989010989010989 0.012
GO:BP GO:0019222 regulation of metabolic process 0.0475092008361065 7148 98 50 0.510204081632653 0.00699496362618914
GO:BP GO:0042100 B cell proliferation 0.0478824524424826 98 91 3 0.032967032967033 0.0306122448979592
GO:BP GO:0048729 tissue morphogenesis 0.0481378100950546 667 14 3 0.214285714285714 0.00449775112443778
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.0484552005135169 1455 91 14 0.153846153846154 0.00962199312714777
GO:BP GO:0046651 lymphocyte proliferation 0.0487113908520208 294 120 6 0.05 0.0204081632653061
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.0488797046592785 1227 97 13 0.134020618556701 0.0105949470252649
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0493579887017317 470 55 5 0.0909090909090909 0.0106382978723404
GO:CC GO:0005829 cytosol 7.66315904181968e-08 5303 97 57 0.587628865979381 0.0107486328493306
GO:CC GO:0005737 cytoplasm 2.89034781025271e-07 11911 144 123 0.854166666666667 0.0103265888674335
GO:CC GO:0030670 phagocytic vesicle membrane 0.000203175585383269 76 104 6 0.0576923076923077 0.0789473684210526
GO:CC GO:0097708 intracellular vesicle 0.000203175585383269 2428 137 38 0.277372262773723 0.0156507413509061
GO:CC GO:0031410 cytoplasmic vesicle 0.000203175585383269 2424 137 38 0.277372262773723 0.0156765676567657
GO:CC GO:0012505 endomembrane system 0.000203175585383269 4640 140 59 0.421428571428571 0.0127155172413793
GO:CC GO:0045335 phagocytic vesicle 0.000203175585383269 137 124 8 0.0645161290322581 0.0583941605839416
GO:CC GO:0030666 endocytic vesicle membrane 0.000389837261156929 159 121 8 0.0661157024793388 0.050314465408805
GO:CC GO:0042824 MHC class I peptide loading complex 0.000453955979869482 9 101 3 0.0297029702970297 0.333333333333333
GO:CC GO:0048471 perinuclear region of cytoplasm 0.000453955979869482 735 58 11 0.189655172413793 0.0149659863945578
GO:CC GO:0030139 endocytic vesicle 0.00104806784075597 306 124 10 0.0806451612903226 0.0326797385620915
GO:CC GO:0031982 vesicle 0.00116731932753578 4055 138 50 0.36231884057971 0.0123304562268804
GO:CC GO:0005794 Golgi apparatus 0.00168178904209921 1623 105 22 0.20952380952381 0.0135551447935921
GO:CC GO:0005622 intracellular anatomical structure 0.00191778851520003 14790 144 130 0.902777777777778 0.00878972278566599
GO:CC GO:0016605 PML body 0.00195620616662585 102 136 6 0.0441176470588235 0.0588235294117647
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.00379996180158052 11296 142 105 0.73943661971831 0.00929532577903683
GO:CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 0.00489729964615974 25 104 3 0.0288461538461538 0.12
GO:CC GO:0098553 lumenal side of endoplasmic reticulum membrane 0.00489729964615974 25 104 3 0.0288461538461538 0.12
GO:CC GO:0012506 vesicle membrane 0.00714934564531732 800 134 15 0.111940298507463 0.01875
GO:CC GO:0031901 early endosome membrane 0.00714934564531732 159 121 6 0.0495867768595041 0.0377358490566038
GO:CC GO:0098576 lumenal side of membrane 0.00943811539232163 33 104 3 0.0288461538461538 0.0909090909090909
GO:CC GO:0005768 endosome 0.00943811539232163 987 137 17 0.124087591240876 0.0172239108409321
GO:CC GO:0005769 early endosome 0.0130544664042596 378 130 9 0.0692307692307692 0.0238095238095238
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.0130544664042596 779 134 14 0.104477611940299 0.0179717586649551
GO:CC GO:0043227 membrane-bounded organelle 0.0130544664042596 12858 142 113 0.795774647887324 0.00878830300202209
GO:CC GO:0010008 endosome membrane 0.0151445557325766 505 121 10 0.0826446280991736 0.0198019801980198
GO:CC GO:0043229 intracellular organelle 0.0168477525823618 12491 142 110 0.774647887323944 0.00880634056520695
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 0.0168477525823618 158 104 5 0.0480769230769231 0.0316455696202532
GO:CC GO:0005576 extracellular region 0.0179304386567665 4567 92 35 0.380434782608696 0.0076636741843661
GO:CC GO:0098588 bounding membrane of organelle 0.0185706079621181 2158 127 26 0.204724409448819 0.0120481927710843
GO:CC GO:0005634 nucleus 0.0190026782800649 7592 144 75 0.520833333333333 0.00987881981032666
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 0.0190026782800649 166 104 5 0.0480769230769231 0.0301204819277108
GO:CC GO:0000502 proteasome complex 0.0224070923441574 66 80 3 0.0375 0.0454545454545455
GO:CC GO:1905369 endopeptidase complex 0.0280694638545862 72 80 3 0.0375 0.0416666666666667
GO:CC GO:0031981 nuclear lumen 0.0386787741753497 4444 69 26 0.376811594202899 0.00585058505850585
GO:CC GO:0031090 organelle membrane 0.0386787741753497 3612 104 31 0.298076923076923 0.00858250276854928
GO:CC GO:0043226 organelle 0.0411777378302528 14008 142 118 0.830985915492958 0.00842375785265563
GO:CC GO:0031965 nuclear membrane 0.0411777378302528 298 138 7 0.0507246376811594 0.023489932885906
GO:CC GO:0005739 mitochondrion 0.0434696811946228 1673 40 9 0.225 0.00537955768081291
GO:CC GO:0005783 endoplasmic reticulum 0.0435629911352729 1982 144 25 0.173611111111111 0.0126135216952573
GO:CC GO:0031984 organelle subcompartment 0.0435629911352729 1773 104 18 0.173076923076923 0.0101522842639594
GO:CC GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 0.0435629911352729 74 101 3 0.0297029702970297 0.0405405405405405
GO:CC GO:0005654 nucleoplasm 0.0462719518782395 4102 69 24 0.347826086956522 0.00585080448561677
GO:MF GO:0003725 double-stranded RNA binding 3.30497046500695e-08 77 90 9 0.1 0.116883116883117
GO:MF GO:0001730 2'-5'-oligoadenylate synthetase activity 3.30497046500695e-08 4 67 4 0.0597014925373134 1
GO:MF GO:0042802 identical protein binding 9.26264558001886e-07 2067 138 40 0.289855072463768 0.019351717464925
GO:MF GO:0046978 TAP1 binding 1.47427901080936e-06 6 104 4 0.0384615384615385 0.666666666666667
GO:MF GO:0046977 TAP binding 9.7804095481826e-06 9 104 4 0.0384615384615385 0.444444444444444
GO:MF GO:0048248 CXCR3 chemokine receptor binding 1.04730289131977e-05 5 47 3 0.0638297872340425 0.6
GO:MF GO:0046979 TAP2 binding 1.04730289131977e-05 3 104 3 0.0288461538461538 1
GO:MF GO:0042605 peptide antigen binding 3.38685445756901e-05 30 104 5 0.0480769230769231 0.166666666666667
GO:MF GO:0042379 chemokine receptor binding 5.444488654301e-05 72 88 6 0.0681818181818182 0.0833333333333333
GO:MF GO:0005525 GTP binding 5.51670015998935e-05 381 56 9 0.160714285714286 0.0236220472440945
GO:MF GO:0097367 carbohydrate derivative binding 5.51670015998935e-05 2285 57 21 0.368421052631579 0.00919037199124726
GO:MF GO:0015440 ABC-type peptide transporter activity 5.51670015998935e-05 5 101 3 0.0297029702970297 0.6
GO:MF GO:0032549 ribonucleoside binding 5.51670015998935e-05 389 56 9 0.160714285714286 0.0231362467866324
GO:MF GO:0032550 purine ribonucleoside binding 5.51670015998935e-05 386 56 9 0.160714285714286 0.0233160621761658
GO:MF GO:0003950 NAD+ ADP-ribosyltransferase activity 5.51670015998935e-05 27 141 5 0.0354609929078014 0.185185185185185
GO:MF GO:0001883 purine nucleoside binding 5.51670015998935e-05 389 56 9 0.160714285714286 0.0231362467866324
GO:MF GO:0015433 ABC-type peptide antigen transporter activity 5.51670015998935e-05 5 101 3 0.0297029702970297 0.6
GO:MF GO:0001882 nucleoside binding 5.83211797686557e-05 395 56 9 0.160714285714286 0.0227848101265823
GO:MF GO:0017111 nucleoside-triphosphatase activity 5.83211797686557e-05 872 119 19 0.159663865546218 0.0217889908256881
GO:MF GO:0019001 guanyl nucleotide binding 5.96491416105801e-05 403 56 9 0.160714285714286 0.0223325062034739
GO:MF GO:0032561 guanyl ribonucleotide binding 5.96491416105801e-05 403 56 9 0.160714285714286 0.0223325062034739
GO:MF GO:0005164 tumor necrosis factor receptor binding 6.07203445258867e-05 32 17 3 0.176470588235294 0.09375
GO:MF GO:0042288 MHC class I protein binding 6.93942847188183e-05 20 101 4 0.0396039603960396 0.2
GO:MF GO:0016763 transferase activity, transferring pentosyl groups 7.21371815086572e-05 56 141 6 0.0425531914893617 0.107142857142857
GO:MF GO:0042803 protein homodimerization activity 7.59494880701919e-05 676 56 11 0.196428571428571 0.0162721893491124
GO:MF GO:1990404 protein ADP-ribosylase activity 8.62787492579643e-05 16 140 4 0.0285714285714286 0.25
GO:MF GO:0035639 purine ribonucleoside triphosphate binding 8.70492803676134e-05 1847 57 18 0.315789473684211 0.00974553329723877
GO:MF GO:0070566 adenylyltransferase activity 8.93236727716187e-05 33 67 4 0.0597014925373134 0.121212121212121
GO:MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 9.06510974633053e-05 930 119 19 0.159663865546218 0.0204301075268817
GO:MF GO:0016462 pyrophosphatase activity 9.06510974633053e-05 928 119 19 0.159663865546218 0.0204741379310345
GO:MF GO:0016817 hydrolase activity, acting on acid anhydrides 9.06510974633053e-05 930 119 19 0.159663865546218 0.0204301075268817
GO:MF GO:0032555 purine ribonucleotide binding 0.000124641940745394 1918 57 18 0.315789473684211 0.00938477580813347
GO:MF GO:0017076 purine nucleotide binding 0.000132636802197205 1933 57 18 0.315789473684211 0.00931195033626487
GO:MF GO:0032553 ribonucleotide binding 0.000132636802197205 1935 57 18 0.315789473684211 0.00930232558139535
GO:MF GO:0005515 protein binding 0.000136522163403669 14767 106 100 0.943396226415094 0.00677185616577504
GO:MF GO:0032813 tumor necrosis factor receptor superfamily binding 0.000136522163403669 49 17 3 0.176470588235294 0.0612244897959184
GO:MF GO:0045236 CXCR chemokine receptor binding 0.000140197252352119 18 47 3 0.0638297872340425 0.166666666666667
GO:MF GO:0044389 ubiquitin-like protein ligase binding 0.000257715819720571 314 91 9 0.0989010989010989 0.0286624203821656
GO:MF GO:0000166 nucleotide binding 0.000324049193231373 2171 60 19 0.316666666666667 0.00875172731460157
GO:MF GO:1901265 nucleoside phosphate binding 0.000324049193231373 2172 60 19 0.316666666666667 0.00874769797421731
GO:MF GO:0008009 chemokine activity 0.000359802053798525 49 70 4 0.0571428571428571 0.0816326530612245
GO:MF GO:0005126 cytokine receptor binding 0.000482318026467555 275 88 8 0.0909090909090909 0.0290909090909091
GO:MF GO:0003924 GTPase activity 0.000544483859880313 328 56 7 0.125 0.0213414634146341
GO:MF GO:0042287 MHC protein binding 0.00055646149048061 39 101 4 0.0396039603960396 0.102564102564103
GO:MF GO:0043168 anion binding 0.000564100184129994 2418 57 19 0.333333333333333 0.00785773366418528
GO:MF GO:0005125 cytokine activity 0.000669613867228356 235 81 7 0.0864197530864197 0.0297872340425532
GO:MF GO:0016787 hydrolase activity 0.000795573456344697 2615 101 29 0.287128712871287 0.0110898661567878
GO:MF GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 0.000795573456344697 35 126 4 0.0317460317460317 0.114285714285714
GO:MF GO:0098772 molecular function regulator 0.00103308277301778 2363 86 24 0.27906976744186 0.0101565806178587
GO:MF GO:0005488 binding 0.00167116303050046 17074 95 95 1 0.00556401546210613
GO:MF GO:0036094 small molecule binding 0.00175569228791398 2506 60 19 0.316666666666667 0.00758180367118915
GO:MF GO:0003824 catalytic activity 0.00184355972834834 5896 113 54 0.47787610619469 0.00915875169606513
GO:MF GO:0140359 ABC-type transporter activity 0.00203374702066296 23 101 3 0.0297029702970297 0.130434782608696
GO:MF GO:0046983 protein dimerization activity 0.00225231220762138 1069 56 11 0.196428571428571 0.010289990645463
GO:MF GO:0030545 receptor regulator activity 0.0030910638405835 545 47 7 0.148936170212766 0.0128440366972477
GO:MF GO:0004842 ubiquitin-protein transferase activity 0.00352986760106424 442 139 11 0.079136690647482 0.0248868778280543
GO:MF GO:0003727 single-stranded RNA binding 0.00370532546989316 92 133 5 0.037593984962406 0.0543478260869565
GO:MF GO:0005102 signaling receptor binding 0.00400205629131674 1672 101 20 0.198019801980198 0.0119617224880383
GO:MF GO:0019787 ubiquitin-like protein transferase activity 0.00487465283505232 465 139 11 0.079136690647482 0.0236559139784946
GO:MF GO:0003724 RNA helicase activity 0.00608516062829325 76 106 4 0.0377358490566038 0.0526315789473684
GO:MF GO:1904680 peptide transmembrane transporter activity 0.00680740542209865 37 101 3 0.0297029702970297 0.0810810810810811
GO:MF GO:0019239 deaminase activity 0.00816423106578454 32 126 3 0.0238095238095238 0.09375
GO:MF GO:0048018 receptor ligand activity 0.00838412433269387 494 81 8 0.0987654320987654 0.0161943319838057
GO:MF GO:0016779 nucleotidyltransferase activity 0.00866042023120466 135 67 4 0.0597014925373134 0.0296296296296296
GO:MF GO:0030546 signaling receptor activator activity 0.00874031660270563 501 81 8 0.0987654320987654 0.0159680638722555
GO:MF GO:0048020 CCR chemokine receptor binding 0.00874031660270563 48 88 3 0.0340909090909091 0.0625
GO:MF GO:0140098 catalytic activity, acting on RNA 0.0102585323679444 395 106 8 0.0754716981132075 0.020253164556962
GO:MF GO:0003823 antigen binding 0.0116514652675481 163 104 5 0.0480769230769231 0.0306748466257669
GO:MF GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters 0.0121014345115071 37 133 3 0.0225563909774436 0.0810810810810811
GO:MF GO:0001664 G protein-coupled receptor binding 0.0130781587961221 292 88 6 0.0681818181818182 0.0205479452054795
GO:MF GO:0004532 exoribonuclease activity 0.0132865534878716 39 133 3 0.0225563909774436 0.0769230769230769
GO:MF GO:0003723 RNA binding 0.013651461873735 1943 113 22 0.194690265486726 0.011322696860525
GO:MF GO:0016887 ATPase activity 0.0137168402730076 488 113 9 0.079646017699115 0.0184426229508197
GO:MF GO:0004386 helicase activity 0.0141933453727831 162 113 5 0.0442477876106195 0.0308641975308642
GO:MF GO:0019899 enzyme binding 0.0160409518965453 2074 95 20 0.210526315789474 0.00964320154291225
GO:MF GO:0042887 amide transmembrane transporter activity 0.0173817791364352 58 101 3 0.0297029702970297 0.0517241379310345
GO:MF GO:1901363 heterocyclic compound binding 0.0195680225036096 6228 69 34 0.492753623188406 0.0054592164418754
GO:MF GO:0097159 organic cyclic compound binding 0.0229504030380716 6309 69 34 0.492753623188406 0.00538912664447615
GO:MF GO:0042626 ATPase-coupled transmembrane transporter activity 0.0235990220627858 67 101 3 0.0297029702970297 0.0447761194029851
GO:MF GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 0.0239953895375565 281 77 5 0.0649350649350649 0.0177935943060498
GO:MF GO:0043167 ion binding 0.0244163632469466 6057 57 28 0.491228070175439 0.00462275053656926
GO:MF GO:0016740 transferase activity 0.026149180195147 2357 144 29 0.201388888888889 0.0123037759864234
GO:MF GO:0015399 primary active transmembrane transporter activity 0.0274516853449367 74 101 3 0.0297029702970297 0.0405405405405405
GO:MF GO:0061134 peptidase regulator activity 0.0278301349166493 224 65 4 0.0615384615384615 0.0178571428571429
GO:MF GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.0279618871304572 57 133 3 0.0225563909774436 0.0526315789473684
GO:MF GO:0004540 ribonuclease activity 0.0288554958803367 111 133 4 0.0300751879699248 0.036036036036036
GO:MF GO:0003714 transcription corepressor activity 0.0325282703145736 187 83 4 0.0481927710843374 0.0213903743315508
GO:MF GO:0008270 zinc ion binding 0.0350178083005077 833 126 12 0.0952380952380952 0.014405762304922
GO:MF GO:0030234 enzyme regulator activity 0.0368998476864681 1248 86 12 0.13953488372093 0.00961538461538462
GO:MF GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.0370703271687248 132 126 4 0.0317460317460317 0.0303030303030303
GO:MF GO:0003712 transcription coregulator activity 0.0416619977342327 506 140 9 0.0642857142857143 0.0177865612648221
GO:MF GO:0004197 cysteine-type endopeptidase activity 0.0427618163619519 121 79 3 0.0379746835443038 0.0247933884297521
GO:MF GO:0031625 ubiquitin protein ligase binding 0.042850292291357 296 91 5 0.0549450549450549 0.0168918918918919
GO:MF GO:0004518 nuclease activity 0.0458257613879183 207 133 5 0.037593984962406 0.0241545893719807
GO:MF GO:0061135 endopeptidase regulator activity 0.0490816591600278 188 55 3 0.0545454545454545 0.0159574468085106
HP HP:0030355 Abnormal serum interferon-gamma level 0.000462447294436749 11 80 5 0.0625 0.454545454545455
HP HP:0030354 Abnormal serum interferon level 0.000462447294436749 11 80 5 0.0625 0.454545454545455
HP HP:0011112 Abnormality of serum cytokine level 0.0177331253661078 23 80 5 0.0625 0.217391304347826
HP HP:0011111 Abnormality of immune serum protein physiology 0.0177331253661078 24 80 5 0.0625 0.208333333333333
KEGG KEGG:05164 Influenza A 2.14103843201096e-09 169 85 16 0.188235294117647 0.0946745562130177
KEGG KEGG:05171 Coronavirus disease - COVID-19 1.01274556228055e-06 231 65 13 0.2 0.0562770562770563
KEGG KEGG:05169 Epstein-Barr virus infection 1.01274556228055e-06 198 104 15 0.144230769230769 0.0757575757575758
KEGG KEGG:05160 Hepatitis C 1.01274556228055e-06 157 63 11 0.174603174603175 0.0700636942675159
KEGG KEGG:04621 NOD-like receptor signaling pathway 1.14526460773036e-06 177 72 12 0.166666666666667 0.0677966101694915
KEGG KEGG:05162 Measles 2.56889601203653e-06 139 64 10 0.15625 0.0719424460431655
KEGG KEGG:04612 Antigen processing and presentation 0.00402770981900473 69 104 6 0.0576923076923077 0.0869565217391304
KEGG KEGG:04061 Viral protein interaction with cytokine and cytokine receptor 0.0183254975759334 98 70 5 0.0714285714285714 0.0510204081632653
KEGG KEGG:04217 Necroptosis 0.0183254975759334 159 65 6 0.0923076923076923 0.0377358490566038
KEGG KEGG:04062 Chemokine signaling pathway 0.0183254975759334 190 91 8 0.0879120879120879 0.0421052631578947
KEGG KEGG:05168 Herpes simplex virus 1 infection 0.0183254975759334 494 104 15 0.144230769230769 0.0303643724696356
KEGG KEGG:04623 Cytosolic DNA-sensing pathway 0.0354590576361164 62 84 4 0.0476190476190476 0.0645161290322581
KEGG KEGG:05165 Human papillomavirus infection 0.0390730195898927 331 78 9 0.115384615384615 0.027190332326284
MIRNA MIRNA:hsa-miR-146a-5p hsa-miR-146a-5p 4.69215476207405e-13 200 67 16 0.238805970149254 0.08
MIRNA MIRNA:hsa-miR-202-5p hsa-miR-202-5p 0.0226772157265662 87 65 5 0.0769230769230769 0.0574712643678161
MIRNA MIRNA:hsa-miR-1-3p hsa-miR-1-3p 0.0432404896056282 915 90 16 0.177777777777778 0.0174863387978142
REAC REAC:R-HSA-913531 Interferon Signaling 1.39363021145965e-42 191 121 43 0.355371900826446 0.225130890052356
REAC REAC:R-HSA-909733 Interferon alpha/beta signaling 1.77005974442421e-36 66 115 28 0.243478260869565 0.424242424242424
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 6.29996499365793e-22 842 121 50 0.413223140495868 0.0593824228028504
REAC REAC:R-HSA-877300 Interferon gamma signaling 3.47713495940072e-16 87 121 18 0.148760330578512 0.206896551724138
REAC REAC:R-HSA-168256 Immune System 2.01240606634078e-15 2139 122 67 0.549180327868853 0.0313230481533427
REAC REAC:R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 6.55230181687149e-14 78 84 14 0.166666666666667 0.179487179487179
REAC REAC:R-HSA-1169408 ISG15 antiviral mechanism 9.8347560973886e-09 70 84 10 0.119047619047619 0.142857142857143
REAC REAC:R-HSA-8983711 OAS antiviral response 1.88018776754691e-07 9 84 5 0.0595238095238095 0.555555555555556
REAC REAC:R-HSA-1236975 Antigen processing-Cross presentation 7.39196136029619e-07 99 121 11 0.0909090909090909 0.111111111111111
REAC REAC:R-HSA-983169 Class I MHC mediated antigen processing & presentation 3.20224879965987e-06 370 139 20 0.143884892086331 0.0540540540540541
REAC REAC:R-HSA-1236974 ER-Phagosome pathway 5.71756770908433e-05 83 104 8 0.0769230769230769 0.0963855421686747
REAC REAC:R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 0.000137986932737827 25 104 5 0.0480769230769231 0.2
REAC REAC:R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 0.00021851988681211 34 84 5 0.0595238095238095 0.147058823529412
REAC REAC:R-HSA-1280218 Adaptive Immune System 0.00125327402327709 800 139 25 0.179856115107914 0.03125
REAC REAC:R-HSA-9683610 Maturation of nucleoprotein 0.00690662859079205 10 140 3 0.0214285714285714 0.3
REAC REAC:R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 0.00690662859079205 50 121 5 0.0413223140495868 0.1
REAC REAC:R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 0.00853913715670941 76 84 5 0.0595238095238095 0.0657894736842105
REAC REAC:R-HSA-8939902 Regulation of RUNX2 expression and activity 0.016053640851111 71 26 3 0.115384615384615 0.0422535211267606
REAC REAC:R-HSA-196807 Nicotinate metabolism 0.016053640851111 31 140 4 0.0285714285714286 0.129032258064516
REAC REAC:R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 0.0162495560508947 308 139 12 0.0863309352517986 0.038961038961039
REAC REAC:R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 0.0371408581910769 100 26 3 0.115384615384615 0.03
REAC REAC:R-HSA-197264 Nicotinamide salvaging 0.0371408581910769 19 140 3 0.0214285714285714 0.157894736842105
REAC REAC:R-HSA-380108 Chemokine receptors bind chemokines 0.0383743143663414 57 47 3 0.0638297872340425 0.0526315789473684
TF TF:M11685 Factor: IRF-8; motif: NCGAAACYGAAACYN 8.85651454265966e-41 1617 143 76 0.531468531468531 0.0470006184291899
TF TF:M04020 Factor: IRF8; motif: NCGAAACCGAAACT 2.27855847651163e-35 992 143 59 0.412587412587413 0.0594758064516129
TF TF:M11664 Factor: IRF-2; motif: NGAAASYGAAAS 3.40044078384031e-35 1651 143 71 0.496503496503497 0.0430042398546336
TF TF:M09957 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN 4.54336351221205e-35 272 143 38 0.265734265734266 0.139705882352941
TF TF:M11665 Factor: IRF-2; motif: NGAAASYGAAAS 2.69127627008938e-34 2396 143 81 0.566433566433566 0.0338063439065108
TF TF:M08775_1 Factor: IRF-2; motif: NAANYGAAASYR; match class: 1 1.11351802678129e-32 2761 143 84 0.587412587412587 0.0304237595074248
TF TF:M04788 Factor: IRF-1; motif: STTTCACTTTCNNT 1.53608042308152e-32 536 143 45 0.314685314685315 0.083955223880597
TF TF:M07216 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT 1.8948330348184e-32 440 143 42 0.293706293706294 0.0954545454545455
TF TF:M08887 Factor: IRF; motif: NNGAAANTGAAANN 3.05210635327109e-32 1267 143 61 0.426573426573427 0.0481452249408051
TF TF:M11670 Factor: IRF-5; motif: NYGAAACCGAAACY 3.05210635327109e-32 871 143 53 0.370629370629371 0.060849598163031
TF TF:M04014 Factor: IRF3; motif: NNRRAANGGAAACCGAAACYR 3.10911620427463e-32 278 143 36 0.251748251748252 0.129496402877698
TF TF:M11679 Factor: IRF-7; motif: NCGAAANCGAAANYN 3.98247205885465e-31 622 143 46 0.321678321678322 0.0739549839228296
TF TF:M11686 Factor: IRF-4; motif: NYGAAASYGAAACYN 9.25634851773206e-31 3391 143 89 0.622377622377622 0.0262459451489236
TF TF:M11685_1 Factor: IRF-8; motif: NCGAAACYGAAACYN; match class: 1 1.11134281572788e-30 118 143 27 0.188811188811189 0.228813559322034
TF TF:M09733_1 Factor: STAT2; motif: NRGAAANNGAAACTNA; match class: 1 1.334637619285e-30 367 143 38 0.265734265734266 0.103542234332425
TF TF:M10080 Factor: STAT2; motif: RRGRAANNGAAACTGAAAN 8.4902270780548e-30 356 143 37 0.258741258741259 0.103932584269663
TF TF:M04018 Factor: IRF7; motif: NCGAAARYGAAANT 5.31355088903251e-29 619 143 44 0.307692307692308 0.0710823909531502
TF TF:M00453 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN 1.11663546803927e-28 3082 143 83 0.58041958041958 0.026930564568462
TF TF:M11683_1 Factor: IRF-8; motif: NCGAAACCGAAACYN; match class: 1 2.3496539819688e-28 814 143 48 0.335664335664336 0.058968058968059
TF TF:M09733 Factor: STAT2; motif: NRGAAANNGAAACTNA 2.61415702702876e-28 2842 144 80 0.555555555555556 0.0281491907107671
TF TF:M04015 Factor: IRF-4; motif: NCGAAACCGAAACYA 3.2418503283396e-28 2038 143 69 0.482517482517482 0.0338567222767419
TF TF:M11682 Factor: IRF-8; motif: NYGAAASYGAAACYN 5.10371411272053e-28 3795 143 90 0.629370629370629 0.0237154150197628
TF TF:M11682_1 Factor: IRF-8; motif: NYGAAASYGAAACYN; match class: 1 6.20014392219531e-28 543 143 41 0.286713286713287 0.0755064456721915
TF TF:M11664_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 2.17747900835981e-27 140 140 26 0.185714285714286 0.185714285714286
TF TF:M11687 Factor: IRF-4; motif: NCGAAACCGAAACYN 2.57121275162683e-27 3595 143 87 0.608391608391608 0.0242002781641168
TF TF:M11671 Factor: IRF-5; motif: NCGAAACCGAAACY 2.60444045590484e-27 389 143 36 0.251748251748252 0.0925449871465296
TF TF:M11684_1 Factor: IRF-8; motif: NYGAAACYGAAACTN; match class: 1 5.35542740926501e-27 832 143 47 0.328671328671329 0.0564903846153846
TF TF:M11677 Factor: IRF-3; motif: NGGAAACNGAAACCGAAACN 7.82790211592367e-27 470 143 38 0.265734265734266 0.0808510638297872
TF TF:M08887_1 Factor: IRF; motif: NNGAAANTGAAANN; match class: 1 4.53278590670551e-26 73 143 21 0.146853146853147 0.287671232876712
TF TF:M07045 Factor: IRF-1; motif: NNRAAANNGAAASN 6.00978929640291e-26 535 143 39 0.272727272727273 0.0728971962616822
TF TF:M11686_1 Factor: IRF-4; motif: NYGAAASYGAAACYN; match class: 1 4.38969555238635e-25 452 143 36 0.251748251748252 0.079646017699115
TF TF:M09629 Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN 8.73842404001452e-25 336 140 32 0.228571428571429 0.0952380952380952
TF TF:M11665_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 1.11134372962849e-24 246 143 29 0.202797202797203 0.117886178861789
TF TF:M00453_1 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN; match class: 1 1.15622543303371e-24 332 143 32 0.223776223776224 0.0963855421686747
TF TF:M11676 Factor: IRF-3; motif: NGGAAANGGAAASNGAAACN 1.83679714402704e-24 562 131 37 0.282442748091603 0.0658362989323843
TF TF:M00772 Factor: IRF; motif: RRAANTGAAASYGNV 4.44409413894702e-24 1029 143 48 0.335664335664336 0.0466472303206997
TF TF:M11687_1 Factor: IRF-4; motif: NCGAAACCGAAACYN; match class: 1 2.81959295838147e-23 474 143 35 0.244755244755245 0.0738396624472574
TF TF:M11683 Factor: IRF-8; motif: NCGAAACCGAAACYN 3.71709966293939e-23 4690 144 93 0.645833333333333 0.0198294243070362
TF TF:M09956 Factor: IRF-1; motif: NAAANNGAAASTGAAASNRN 8.26266263111779e-23 317 143 30 0.20979020979021 0.0946372239747634
TF TF:M11684 Factor: IRF-8; motif: NYGAAACYGAAACTN 1.34947768993029e-22 4664 144 92 0.638888888888889 0.0197255574614065
TF TF:M00258 Factor: ISGF-3; motif: CAGTTTCWCTTTYCC 3.34953908201485e-20 823 143 40 0.27972027972028 0.0486026731470231
TF TF:M08775 Factor: IRF-2; motif: NAANYGAAASYR 1.16682007914431e-18 8370 141 114 0.808510638297872 0.0136200716845878
TF TF:M07323 Factor: IRF-4; motif: KRAAMNGAAANYN 3.65168794069046e-18 938 143 40 0.27972027972028 0.0426439232409382
TF TF:M11680 Factor: IRF-9; motif: NYGAAACYGAAACYN 1.08860852761407e-17 128 143 19 0.132867132867133 0.1484375
TF TF:M00699 Factor: ICSBP; motif: RAARTGAAACTG 4.1450245951002e-17 1184 143 43 0.300699300699301 0.0363175675675676
TF TF:M11681 Factor: IRF-9; motif: NCGAAACYGAAACYN 5.23488077594703e-17 97 143 17 0.118881118881119 0.175257731958763
TF TF:M04015_1 Factor: IRF-4; motif: NCGAAACCGAAACYA; match class: 1 6.01115102967599e-16 158 143 19 0.132867132867133 0.120253164556962
TF TF:M09958 Factor: IRF-3; motif: RAAARGGAAANNGAAASNGA 6.01115102967599e-16 589 135 30 0.222222222222222 0.0509337860780985
TF TF:M04016 Factor: IRF5; motif: CCGAAACCGAAACY 7.89641733661766e-16 314 143 24 0.167832167832168 0.0764331210191083
TF TF:M11672 Factor: IRF-5; motif: NCGAAACCGAAACY 2.10497486579826e-15 120 143 17 0.118881118881119 0.141666666666667
TF TF:M00972 Factor: IRF; motif: RAAANTGAAAN 1.55376172444841e-14 1979 143 51 0.356643356643357 0.0257705912076806
TF TF:M00699_1 Factor: ICSBP; motif: RAARTGAAACTG; match class: 1 6.98144872964103e-14 47 143 12 0.0839160839160839 0.25531914893617
TF TF:M11679_1 Factor: IRF-7; motif: NCGAAANCGAAANYN; match class: 1 1.77470916415408e-12 23 131 9 0.0687022900763359 0.391304347826087
TF TF:M04020_1 Factor: IRF8; motif: NCGAAACCGAAACT; match class: 1 1.9620673659545e-12 45 143 11 0.0769230769230769 0.244444444444444
TF TF:M00972_1 Factor: IRF; motif: RAAANTGAAAN; match class: 1 2.29929718100706e-12 205 72 14 0.194444444444444 0.0682926829268293
TF TF:M11670_1 Factor: IRF-5; motif: NYGAAACCGAAACY; match class: 1 7.37767311228134e-12 36 143 10 0.0699300699300699 0.277777777777778
TF TF:M00772_1 Factor: IRF; motif: RRAANTGAAASYGNV; match class: 1 1.36499979315621e-11 57 93 10 0.10752688172043 0.175438596491228
TF TF:M07045_1 Factor: IRF-1; motif: NNRAAANNGAAASN; match class: 1 1.77982009695981e-11 19 126 8 0.0634920634920635 0.421052631578947
TF TF:M10080_1 Factor: STAT2; motif: RRGRAANNGAAACTGAAAN; match class: 1 2.93304688743568e-11 11 141 7 0.049645390070922 0.636363636363636
TF TF:M11673 Factor: IRF-5; motif: NCGAAACCGAAACY 2.98118447825035e-11 57 143 11 0.0769230769230769 0.192982456140351
TF TF:M00258_1 Factor: ISGF-3; motif: CAGTTTCWCTTTYCC; match class: 1 5.78545133855065e-11 30 143 9 0.0629370629370629 0.3
TF TF:M09745 Factor: HELIOS; motif: RNARRRGGAASTGARAN 1.59852399922027e-10 3582 135 60 0.444444444444444 0.016750418760469
TF TF:M11678 Factor: IRF-7; motif: NNGAAAGTGAAANTR 1.60074112482874e-10 179 135 15 0.111111111111111 0.0837988826815642
TF TF:M01882 Factor: IRF-2; motif: NNRAAAGTGAAASNNA 1.69821917641047e-09 258 111 15 0.135135135135135 0.0581395348837209
TF TF:M04017 Factor: IRF5; motif: NACCGAAACYA 2.01813206410979e-09 195 123 14 0.113821138211382 0.0717948717948718
TF TF:M04788_1 Factor: IRF-1; motif: STTTCACTTTCNNT; match class: 1 1.09740486124275e-08 17 93 6 0.0645161290322581 0.352941176470588
TF TF:M00063 Factor: IRF-2; motif: GAAAAGYGAAASY 3.95889142369205e-08 685 138 23 0.166666666666667 0.0335766423357664
TF TF:M11676_1 Factor: IRF-3; motif: NGGAAANGGAAASNGAAACN; match class: 1 3.97338111517076e-08 41 140 8 0.0571428571428571 0.195121951219512
TF TF:M01066 Factor: Blimp-1; motif: NRGRAAGKGAAAGKRN 4.09125237396213e-08 411 135 18 0.133333333333333 0.0437956204379562
TF TF:M01279 Factor: IRF-3; motif: NBNBTTTCSCTTT 2.45851790718102e-07 1647 140 35 0.25 0.021250758955677
TF TF:M04018_1 Factor: IRF7; motif: NCGAAARYGAAANT; match class: 1 3.16433137087159e-07 24 111 6 0.0540540540540541 0.25
TF TF:M09745_1 Factor: HELIOS; motif: RNARRRGGAASTGARAN; match class: 1 3.51958882100715e-07 495 129 18 0.13953488372093 0.0363636363636364
TF TF:M03793 Factor: IRF-7; motif: AARGGAAANNGAA 4.17124482802541e-07 1987 143 39 0.272727272727273 0.019627579265224
TF TF:M10040_1 Factor: Blimp-1; motif: RAAAGNGAAAGTNN; match class: 1 9.39137557627807e-07 12 135 5 0.037037037037037 0.416666666666667
TF TF:M09957_1 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN; match class: 1 2.72051062228143e-06 22 30 4 0.133333333333333 0.181818181818182
TF TF:M01665_1 Factor: IRF-8; motif: AGTTTCW; match class: 1 3.09696156876331e-06 721 22 9 0.409090909090909 0.0124826629680999
TF TF:M09629_1 Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN; match class: 1 4.0506959358776e-06 29 140 6 0.0428571428571429 0.206896551724138
TF TF:M07216_1 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT; match class: 1 1.31941597860743e-05 35 140 6 0.0428571428571429 0.171428571428571
TF TF:M01066_1 Factor: Blimp-1; motif: NRGRAAGKGAAAGKRN; match class: 1 2.51732243774057e-05 11 111 4 0.036036036036036 0.363636363636364
TF TF:M03916 Factor: PRDM1; motif: NRAAAGTGAAAGTNN 3.90523033292158e-05 948 135 22 0.162962962962963 0.0232067510548523
TF TF:M11680_1 Factor: IRF-9; motif: NYGAAACYGAAACYN; match class: 1 4.44908259169186e-05 4 103 3 0.029126213592233 0.75
TF TF:M07121_1 Factor: Blimp-1; motif: NRAAAGTGAAAGTNN; match class: 1 5.32205068343657e-05 11 135 4 0.0296296296296296 0.363636363636364
TF TF:M11674 Factor: IRF-3; motif: GCNGTTTCCWGGAAACNGAAAC 9.33788220662491e-05 4623 108 48 0.444444444444444 0.0103828682673589
TF TF:M07314_1 Factor: Blimp-1; motif: RGRAAGNGAAAG; match class: 1 0.000118387894596588 118 135 8 0.0592592592592593 0.0677966101694915
TF TF:M01665 Factor: IRF-8; motif: AGTTTCW 0.000147645900142994 4771 48 27 0.5625 0.00565919094529449
TF TF:M09956_1 Factor: IRF-1; motif: NAAANNGAAASTGAAASNRN; match class: 1 0.0001598472149114 23 22 3 0.136363636363636 0.130434782608696
TF TF:M00062 Factor: IRF-1; motif: SAAAAGYGAAACC 0.000257579725381059 576 140 16 0.114285714285714 0.0277777777777778
TF TF:M07323_1 Factor: IRF-4; motif: KRAAMNGAAANYN; match class: 1 0.000503460507440829 39 19 3 0.157894736842105 0.0769230769230769
TF TF:M00459_1 Factor: STAT5B; motif: NAWTTCYNGGAAWTN; match class: 1 0.000643334598549552 1896 121 28 0.231404958677686 0.0147679324894515
TF TF:M01883_1 Factor: IRF-4; motif: GAAARTA; match class: 1 0.000783036765399009 2948 65 24 0.369230769230769 0.00814111261872456
TF TF:M03545_1 Factor: c-Rel; motif: NGGGAATYTCCN; match class: 1 0.000840674670185927 1011 53 12 0.226415094339623 0.0118694362017804
TF TF:M03557_1 Factor: P50; motif: GGRRANTCCCNN; match class: 1 0.00101958444491075 1292 114 21 0.184210526315789 0.0162538699690402
TF TF:M09649_1 Factor: Blimp-1; motif: RAAAGTGAAAGTNN; match class: 1 0.00141549761427196 10 111 3 0.027027027027027 0.3
TF TF:M04016_1 Factor: IRF5; motif: CCGAAACCGAAACY; match class: 1 0.00141549761427196 8 143 3 0.020979020979021 0.375
TF TF:M03916_1 Factor: PRDM1; motif: NRAAAGTGAAAGTNN; match class: 1 0.001588333442344 50 135 5 0.037037037037037 0.1
TF TF:M09663 Factor: STAT1; motif: YCMTTTCCNGGAAAWCNCATNN 0.00180168379758554 2762 124 35 0.282258064516129 0.0126719768283852
TF TF:M00346 Factor: GATA-1; motif: NCWGATAACA 0.0020475502791255 4376 73 32 0.438356164383562 0.00731261425959781
TF TF:M00205_1 Factor: GR; motif: GGTACAANNTGTYCTK; match class: 1 0.00212664978483622 1482 54 14 0.259259259259259 0.00944669365721997
TF TF:M11677_1 Factor: IRF-3; motif: NGGAAACNGAAACCGAAACN; match class: 1 0.00212664978483622 26 140 4 0.0285714285714286 0.153846153846154
TF TF:M11453 Factor: ELFR; motif: AAMCAGGAAGTR 0.00219426678219963 488 117 12 0.102564102564103 0.0245901639344262
TF TF:M01260 Factor: STAT1; motif: NNTTTCYNGGAARNNNNNNNNN 0.00225136919121029 2130 141 32 0.226950354609929 0.0150234741784038
TF TF:M11320_1 Factor: C/EBPdelta; motif: NRTTGCGYAAYN; match class: 1 0.0022786480188021 2586 123 33 0.268292682926829 0.0127610208816705
TF TF:M01043_1 Factor: CSX; motif: TSYCACTTSM; match class: 1 0.00250784518148072 1199 8 5 0.625 0.00417014178482068
TF TF:M02015 Factor: HNF-3gamma; motif: TGTTTRYT 0.00251184232203192 2809 47 18 0.382978723404255 0.00640797436810253
TF TF:M01172_1 Factor: PU.1; motif: NNNNYYYACTTCCTCTTTY; match class: 1 0.00258138617402463 580 134 14 0.104477611940299 0.0241379310344828
TF TF:M09649 Factor: Blimp-1; motif: RAAAGTGAAAGTNN 0.00259880441769654 300 135 10 0.0740740740740741 0.0333333333333333
TF TF:M11320 Factor: C/EBPdelta; motif: NRTTGCGYAAYN 0.00266234355008176 5477 126 56 0.444444444444444 0.0102245754975351
TF TF:M01808_1 Factor: NMYC; motif: CAYCTG; match class: 1 0.00306229687653887 6149 56 32 0.571428571428571 0.00520409822735404
TF TF:M09589 Factor: AR; motif: NGNACANNNTGTTCYNN 0.00306690537382424 5130 57 29 0.508771929824561 0.00565302144249513
TF TF:M00447 Factor: AR; motif: AGWACATNWTGTTCT 0.00308665653868121 4183 40 20 0.5 0.0047812574707148
TF TF:M07254 Factor: Foxc1; motif: TTVYTTTNW 0.00317453769943317 7741 88 53 0.602272727272727 0.00684666063816044
TF TF:M03793_1 Factor: IRF-7; motif: AARGGAAANNGAA; match class: 1 0.00318698247220175 138 30 4 0.133333333333333 0.0289855072463768
TF TF:M00208 Factor: NF-kappaB; motif: NGGGACTTTCCA 0.00349628355228646 3757 116 40 0.344827586206897 0.0106467926537131
TF TF:M09933_1 Factor: FOXP1; motif: TNTGTTTMY; match class: 1 0.00450040955041636 634 57 9 0.157894736842105 0.0141955835962145
TF TF:M00638 Factor: HNF4alpha; motif: VTGAACTTTGMMB 0.00470107159500932 2814 37 15 0.405405405405405 0.00533049040511727
TF TF:M11674_1 Factor: IRF-3; motif: GCNGTTTCCWGGAAACNGAAAC; match class: 1 0.00471167224487176 1663 108 22 0.203703703703704 0.0132291040288635
TF TF:M00457 Factor: STAT5A; motif: NAWTTCYNGGAANYN 0.00472913090493911 4038 121 43 0.355371900826446 0.0106488360574542
TF TF:M09899 Factor: ehf; motif: NNANSAGGAAGTNNN 0.00481756582942964 457 117 11 0.094017094017094 0.0240700218818381
TF TF:M00225_1 Factor: STAT3; motif: NGNNATTTCCSGGAARTGNNN; match class: 1 0.00481756582942964 1922 121 26 0.214876033057851 0.0135275754422477
TF TF:M00641_1 Factor: HSF; motif: TTCCMGARGYTTC; match class: 1 0.00494152879496576 387 13 4 0.307692307692308 0.0103359173126615
TF TF:M00208_1 Factor: NF-kappaB; motif: NGGGACTTTCCA; match class: 1 0.00527082506557218 604 106 12 0.113207547169811 0.0198675496688742
TF TF:M11671_1 Factor: IRF-5; motif: NCGAAACCGAAACY; match class: 1 0.00529488836977298 14 131 3 0.0229007633587786 0.214285714285714
TF TF:M07038_1 Factor: DBP; motif: TTRCATAANN; match class: 1 0.00536517250369465 772 84 12 0.142857142857143 0.0155440414507772
TF TF:M04903_1 Factor: HNF-4alpha; motif: AGTCCAAR; match class: 1 0.0055282883446593 1534 72 16 0.222222222222222 0.0104302477183833
TF TF:M00422 Factor: FOXJ2; motif: NNNWAAAYAAAYANNNNN 0.00566363766077851 2538 121 31 0.256198347107438 0.012214342001576
TF TF:M11321 Factor: C/EBPdelta; motif: NRTTGCGYAAYN 0.00579133977971567 5597 65 33 0.507692307692308 0.00589601572270859
TF TF:M11988_1 Factor: NFATc3; motif: NTTTCCRYGGAAAN; match class: 1 0.00579133977971567 6648 72 40 0.555555555555556 0.00601684717208183
TF TF:M07355 Factor: GR; motif: AGAACAN 0.00624020867378998 5862 32 20 0.625 0.00341180484476288
TF TF:M10587 Factor: Barx-2; motif: NWWAAYMATTAN 0.0062975232504715 1776 34 11 0.323529411764706 0.00619369369369369
TF TF:M00225 Factor: STAT3; motif: NGNNATTTCCSGGAARTGNNN 0.00648801352469622 3188 121 36 0.297520661157025 0.0112923462986198
TF TF:M10079 Factor: STAT1; motif: NCCNTTTCCNGGAAANCNC 0.00662688223003006 2284 141 32 0.226950354609929 0.0140105078809107
TF TF:M06454 Factor: ZNF786; motif: KGGWTYAGGGGA 0.00662688223003006 46 112 4 0.0357142857142857 0.0869565217391304
TF TF:M11571 Factor: HNF-3alpha; motif: YTRWGTMAATATTTRCWYWN 0.00684747600444945 4307 66 28 0.424242424242424 0.00650104481077316
TF TF:M08632 Factor: TEF-3:Dlx-2; motif: RMATWCYNNNYAATTA 0.00703654983527407 600 65 9 0.138461538461538 0.015
TF TF:M08295_1 Factor: FOXO1A:Elf-1; motif: NAGAAAACCGAANM; match class: 1 0.00703654983527407 4997 61 29 0.475409836065574 0.00580348208925355
TF TF:M12334 Factor: ZBTB20; motif: NNAAYGTATRKN 0.00703654983527407 1214 121 19 0.15702479338843 0.0156507413509061
TF TF:M11985_1 Factor: NFATc2; motif: TTTTCCATGGAAAA; match class: 1 0.00703654983527407 4518 105 41 0.39047619047619 0.00907481186365649
TF TF:M11383 Factor: ESE-1; motif: ACCAGGAAGTANNNNNNNAAWAA 0.00732047110542611 3886 136 45 0.330882352941176 0.0115800308800823
TF TF:M04317 Factor: EN1; motif: TAATTRSNYAATTA 0.00732047110542611 2735 24 11 0.458333333333333 0.00402193784277879
TF TF:M08817 Factor: HOXD13; motif: WNNAATAAWAY 0.00771671485323447 5669 97 45 0.463917525773196 0.00793790792026812
TF TF:M04360 Factor: HOXD11; motif: NNYMATAAAA 0.00803816469552161 4936 65 30 0.461538461538462 0.00607779578606159
TF TF:M00155 Factor: ARP-1; motif: TGARCCYTTGAMCCCW 0.00855730987090914 5581 121 53 0.43801652892562 0.00949650600250851
TF TF:M09958_1 Factor: IRF-3; motif: RAAARGGAAANNGAAASNGA; match class: 1 0.00862012331301274 93 112 5 0.0446428571428571 0.0537634408602151
TF TF:M08233 Factor: ERF:C/EBPdelta; motif: NNCGGAWRTTGCGCAAY 0.00971217773607607 5782 137 60 0.437956204379562 0.0103770321687997
TF TF:M10040 Factor: Blimp-1; motif: RAAAGNGAAAGTNN 0.00975290229356465 366 135 10 0.0740740740740741 0.0273224043715847
TF TF:M08817_1 Factor: HOXD13; motif: WNNAATAAWAY; match class: 1 0.0102966729277217 1646 79 17 0.215189873417722 0.0103280680437424
TF TF:M02112 Factor: OC-2; motif: TCAATA 0.0102966729277217 7568 104 58 0.557692307692308 0.00766384778012685
TF TF:M03833 Factor: NKX3A; motif: NCACTTANTYN 0.0109652979336996 895 80 12 0.15 0.0134078212290503
TF TF:M00223 Factor: STAT; motif: TTCCCGKAA 0.0114266393198152 3501 123 38 0.308943089430894 0.0108540417023708
TF TF:M10586 Factor: Barx-2; motif: NWWAAYCATTAN 0.0114369044458353 1016 34 8 0.235294117647059 0.0078740157480315
TF TF:M07204 Factor: AR; motif: ARGAACANNNTGTNC 0.0116269538474325 4906 16 11 0.6875 0.00224215246636771
TF TF:M07229 Factor: STAT3; motif: NTTCYKGGAAN 0.0120780782283542 3717 141 44 0.312056737588652 0.0118375033629271
TF TF:M01393 Factor: Msx-2; motif: NNNGACYAATTAGYNNT 0.0124969780795068 8741 25 20 0.8 0.00228806772680471
TF TF:M10082 Factor: STAT4; motif: YTTCYYNGMAN 0.0125907023759407 882 133 16 0.120300751879699 0.018140589569161
TF TF:M11378 Factor: ESE-1; motif: ACMAGGAAGTANNNNNNNWWAWW 0.0129187062940375 3049 117 33 0.282051282051282 0.0108232207281076
TF TF:M09664 Factor: STAT3; motif: NTTCCYGGAAN 0.0129991814963635 5587 123 53 0.430894308943089 0.00948630749955253
TF TF:M01292_1 Factor: HOXA13; motif: ATAAMA; match class: 1 0.0129991814963635 8366 75 47 0.626666666666667 0.00561797752808989
TF TF:M03854_1 Factor: SRY; motif: TTGTTT; match class: 1 0.0129991814963635 9098 79 52 0.658227848101266 0.00571554187733568
TF TF:M00459 Factor: STAT5B; motif: NAWTTCYNGGAAWTN 0.0129991814963635 3076 121 34 0.28099173553719 0.0110533159947984
TF TF:M03823_1 Factor: FOXO1A; motif: AAACAA; match class: 1 0.0129991814963635 9098 79 52 0.658227848101266 0.00571554187733568
TF TF:M08719 Factor: HOXB2:Sox-20; motif: ACAATRSNNNNNNNATYA 0.0129991814963635 1849 128 25 0.1953125 0.0135208220659816
TF TF:M06017 Factor: ZNF586; motif: CCTGCMYGGTGM 0.0132415179269577 94 125 5 0.04 0.0531914893617021
TF TF:M00641 Factor: HSF; motif: TTCCMGARGYTTC 0.0135237493708792 3599 81 28 0.345679012345679 0.00777993887190886
TF TF:M11675 Factor: IRF-3; motif: KCNGTTTCSNSGAAACCGAAACN 0.0135922539835862 4655 80 33 0.4125 0.00708915145005371
TF TF:M00190 Factor: C/EBP; motif: NNATTGCNNAANNN 0.0135922539835862 5586 28 17 0.607142857142857 0.00304332259219477
TF TF:M09941_1 Factor: GR; motif: RGNACANMNTGTNCY; match class: 1 0.0136680379965694 2046 55 15 0.272727272727273 0.00733137829912024
TF TF:M08216 Factor: Elk-1:FOXI1; motif: ACCGGAAGTRTMAACAN 0.0136680379965694 7126 62 36 0.580645161290323 0.00505192253718776
TF TF:M07316 Factor: C/EBPdelta; motif: TKNNGCAATN 0.0137104944547705 3306 136 39 0.286764705882353 0.0117967332123412
TF TF:M07314 Factor: Blimp-1; motif: RGRAAGNGAAAG 0.0142531389953218 1460 135 22 0.162962962962963 0.0150684931506849
TF TF:M04201 Factor: CEBPB; motif: ATTRCGCAAY 0.0148252075764581 4048 19 11 0.578947368421053 0.00271739130434783
TF TF:M10170 Factor: ZNF85; motif: ANAGAARWCTGMWGKAATCT 0.0148252075764581 181 16 3 0.1875 0.0165745856353591
TF TF:M00457_1 Factor: STAT5A; motif: NAWTTCYNGGAANYN; match class: 1 0.0151705291514522 1589 117 21 0.179487179487179 0.013215859030837
TF TF:M00747_1 Factor: IRF-1; motif: TTCACTT; match class: 1 0.0159093024906788 933 22 6 0.272727272727273 0.00643086816720257
TF TF:M09882 Factor: C/EBPdelta; motif: NTTGCNCMAYN 0.0159093024906788 2027 140 28 0.2 0.0138135175135668
TF TF:M05445_1 Factor: GATA-5; motif: TTAMCAR; match class: 1 0.0159093024906788 414 47 6 0.127659574468085 0.0144927536231884
TF TF:M07419 Factor: FOXP3; motif: NNNVAAACANWD 0.0160872145064882 6311 79 40 0.506329113924051 0.00633813975598162
TF TF:M08413 Factor: TEF-3:C/EBPdelta; motif: RGWATGYNRTTRCGYAAY 0.0161428789737268 6035 72 36 0.5 0.00596520298260149
TF TF:M03564_1 Factor: SATB1; motif: NTTTAT; match class: 1 0.0167217446548192 12003 144 107 0.743055555555556 0.00891443805715238
TF TF:M01279_1 Factor: IRF-3; motif: NBNBTTTCSCTTT; match class: 1 0.0172873112305635 101 30 3 0.1 0.0297029702970297
TF TF:M09596 Factor: C/EBPalpha; motif: NRTTGTGCAAYNN 0.0174487885436673 5213 136 54 0.397058823529412 0.010358718588145
TF TF:M07298 Factor: Msx-1; motif: AHAWWTSMYYCAATTAN 0.0174942509960281 1938 72 17 0.236111111111111 0.0087719298245614
TF TF:M04715_1 Factor: Oct-2; motif: ATTTGCA; match class: 1 0.0175592526302455 1767 100 20 0.2 0.0113186191284663
TF TF:M10079_1 Factor: STAT1; motif: NCCNTTTCCNGGAAANCNC; match class: 1 0.0178208007372732 1164 117 17 0.145299145299145 0.0146048109965636
TF TF:M02117 Factor: STAT4; motif: TTMNNRGAAA 0.0179670560827418 1353 139 21 0.151079136690647 0.0155210643015521
TF TF:M09929 Factor: FOXK1; motif: TGTTTNCNNT 0.0179670560827418 4139 105 37 0.352380952380952 0.00893935733268906
TF TF:M02096 Factor: ipf1; motif: YTAATGN 0.0179670560827418 2033 5 4 0.8 0.00196753566158387
TF TF:M00791 Factor: HNF3; motif: NWRARYAAAYANN 0.0179963342952009 2732 23 10 0.434782608695652 0.00366032210834553
TF TF:M04431 Factor: PRRX1; motif: NYAATTAN 0.0180636136054346 3464 90 29 0.322222222222222 0.00837182448036951
TF TF:M00687 Factor: alpha-CP1; motif: CAGCCAATGAG 0.0184537641366734 2326 18 8 0.444444444444444 0.00343938091143594
TF TF:M11321_1 Factor: C/EBPdelta; motif: NRTTGCGYAAYN; match class: 1 0.0184537641366734 1852 125 24 0.192 0.0129589632829374
TF TF:M07228 Factor: STAT1; motif: NTTCYRGGAAA 0.0185892523371694 1919 121 24 0.198347107438017 0.0125065138092757
TF TF:M01797 Factor: SIRT6; motif: AGATAARN 0.0185892523371694 1200 25 7 0.28 0.00583333333333333
TF TF:M07988_1 Factor: EMX1; motif: NNTAATKANN; match class: 1 0.0185892523371694 1621 86 17 0.197674418604651 0.0104873534855028
TF TF:M00194_1 Factor: NF-kappaB; motif: NGGGGAMTTTCCNN; match class: 1 0.0187865989207555 385 53 6 0.113207547169811 0.0155844155844156
TF TF:M04681 Factor: JunD; motif: RTGACGTCA 0.0189224286342549 6003 115 52 0.452173913043478 0.00866233549891721
TF TF:M11286 Factor: Fra-1; motif: NATGAWTCAYN 0.0189224286342549 3150 72 23 0.319444444444444 0.0073015873015873
TF TF:M08359_1 Factor: HOXD12:Elk-1; motif: NRNCGGAAGTCGTAAAN; match class: 1 0.0189836845293064 1166 68 12 0.176470588235294 0.0102915951972556
TF TF:M00054_1 Factor: NF-kappaB; motif: GGGAMTTYCC; match class: 1 0.0189967828628772 712 53 8 0.150943396226415 0.0112359550561798
TF TF:M04324 Factor: GBX2; motif: NNYAATTANN 0.0189967828628772 3485 90 29 0.322222222222222 0.00832137733142037
TF TF:M03865 Factor: Blimp-1; motif: NRGRAAGKGAAAGK 0.0194575779872133 1048 21 6 0.285714285714286 0.00572519083969466
TF TF:M02079 Factor: Isl2; motif: CTAATKR 0.0194575779872133 5734 6 6 1 0.00104638995465644
TF TF:M11589 Factor: FOXK1; motif: NNNGTAAACAN 0.0196026778094594 4486 59 25 0.423728813559322 0.00557289344627731
TF TF:M04325 Factor: GSC2; motif: NNTAATCCNN 0.0199945812020852 3592 42 17 0.404761904761905 0.00473273942093541
TF TF:M01996 Factor: AR; motif: GNNCNNNNTGTTCTN 0.0200742703647413 3085 36 14 0.388888888888889 0.00453808752025932
TF TF:M10690 Factor: HOXA7; motif: GYMATTAN 0.0209254847698118 10748 55 42 0.763636363636364 0.00390770375883885
TF TF:M12067 Factor: ZNF32; motif: NYGTAACNYGAYACC 0.0212107518621837 164 84 5 0.0595238095238095 0.0304878048780488
TF TF:M11316 Factor: C/EBPbeta; motif: NRTTGCGYAAYN 0.0212107518621837 5225 21 13 0.619047619047619 0.00248803827751196
TF TF:M11988 Factor: NFATc3; motif: NTTTCCRYGGAAAN 0.0212107518621837 7175 72 40 0.555555555555556 0.00557491289198606
TF TF:M10941 Factor: VSX1; motif: CYAATTRN 0.0212107518621837 3970 103 35 0.339805825242718 0.00881612090680101
TF TF:M00809 Factor: FOX; motif: KWTTGTTTRTTTW 0.0212107518621837 3746 137 42 0.306569343065693 0.0112119594233849
TF TF:M11566 Factor: HNF-3alpha; motif: NWRWGTMAAYAW 0.0212107518621837 3516 62 22 0.354838709677419 0.00625711035267349
TF TF:M00070 Factor: Tal-1beta:ITF-2; motif: NNNAACAGATGKTNNN 0.0213110826565886 1763 67 15 0.223880597014925 0.00850822461712989
TF TF:M00465 Factor: POU6F1; motif: GCATAAWTTAT 0.0214350656616938 1511 62 13 0.209677419354839 0.0086035737921906
TF TF:M00130 Factor: FOXD3; motif: NAWTGTTTRTTT 0.0214350656616938 4211 138 46 0.333333333333333 0.010923771075754
TF TF:M01886 Factor: NFATc3; motif: GGAAAA 0.0214350656616938 16226 89 84 0.943820224719101 0.00517687661777394
TF TF:M02108_1 Factor: CSX; motif: NNCACTTGNRN; match class: 1 0.0214350656616938 1533 135 22 0.162962962962963 0.0143509458577952
TF TF:M03555 Factor: NFATc2; motif: GGAAAA 0.0214350656616938 16226 89 84 0.943820224719101 0.00517687661777394
TF TF:M01281 Factor: NFATc2; motif: GGAAAA 0.0214350656616938 16226 89 84 0.943820224719101 0.00517687661777394
TF TF:M09902 Factor: ESE-1; motif: NNANVAGGAAGTNN 0.0217328565041982 3200 117 33 0.282051282051282 0.0103125
TF TF:M11317 Factor: C/EBPbeta; motif: NRTTGCGYAAYN 0.0217328565041982 4365 71 28 0.394366197183099 0.00641466208476518
TF TF:M01230_1 Factor: ZNF333; motif: ATAAT; match class: 1 0.0217328565041982 11582 77 59 0.766233766233766 0.00509411155240891
TF TF:M01181 Factor: Nkx3-2; motif: TRAGTG 0.0217328565041982 9457 105 67 0.638095238095238 0.00708469916463995
TF TF:M09589_1 Factor: AR; motif: NGNACANNNTGTTCYNN; match class: 1 0.0222253776634789 1159 20 6 0.3 0.00517687661777394
TF TF:M00476 Factor: FOXO4; motif: NNGTTGTTTACNTN 0.0223768611548728 2740 64 19 0.296875 0.00693430656934307
TF TF:M10526_1 Factor: Blimp-1; motif: RRGNGAAAGNRANNN; match class: 1 0.0223768611548728 286 135 8 0.0592592592592593 0.027972027972028
TF TF:M03563 Factor: RelA-p65; motif: GGGANTTTCCNN 0.0223768611548728 4643 55 24 0.436363636363636 0.00516907172087013
TF TF:M11847_1 Factor: GR; motif: RGWACATWATGTWCY; match class: 1 0.0223768611548728 4066 55 22 0.4 0.00541072306935563
TF TF:M03882 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC 0.0223768611548728 4474 60 25 0.416666666666667 0.00558784085829236
TF TF:M02014 Factor: HNF-3beta; motif: NTRTTTRYT 0.0223768611548728 2650 61 18 0.295081967213115 0.00679245283018868
TF TF:M08004 Factor: SHOX; motif: NTAATTRN 0.0224979429621002 2226 66 17 0.257575757575758 0.00763701707097934
TF TF:M00774 Factor: NF-kappaB; motif: NGGGANTTYCCMNNNN 0.0227680233977549 1818 53 13 0.245283018867925 0.00715071507150715
TF TF:M10541_1 Factor: SUHW1; motif: TCTCTCCAGTRTGAATTCTCTGAT; match class: 1 0.0227692644961682 1794 67 15 0.223880597014925 0.00836120401337793
TF TF:M00621 Factor: C/EBPdelta; motif: MATTKCNTMAYY 0.0231693309658395 3888 72 26 0.361111111111111 0.00668724279835391
TF TF:M11458 Factor: nerf; motif: AANCMGGAAGTR 0.0231693309658395 505 117 10 0.0854700854700855 0.0198019801980198
TF TF:M04745_1 Factor: CTCF; motif: CANNWRRTGGCAG; match class: 1 0.0236654936917662 2298 8 5 0.625 0.00217580504786771
TF TF:M11445 Factor: Elf-1; motif: NANCAGGAAGTR 0.0237655255044556 1689 117 21 0.179487179487179 0.0124333925399645
TF TF:M02015_1 Factor: HNF-3gamma; motif: TGTTTRYT; match class: 1 0.0242980984666592 742 31 6 0.193548387096774 0.00808625336927224
TF TF:M09902_1 Factor: ESE-1; motif: NNANVAGGAAGTNN; match class: 1 0.0244158458474143 306 129 8 0.062015503875969 0.0261437908496732
TF TF:M08520_1 Factor: CDP:SRF; motif: NCCWTAYAAGGTMNKRATCRATN; match class: 1 0.0250862418924995 3278 47 17 0.361702127659574 0.00518608907870653
TF TF:M01866 Factor: C/EBPalpha; motif: NNNTTNNGCAANN 0.0250862418924995 5089 27 15 0.555555555555556 0.00294753389663981
TF TF:M11985 Factor: NFATc2; motif: TTTTCCATGGAAAA 0.0257705834467219 5845 74 35 0.472972972972973 0.00598802395209581
TF TF:M09597_1 Factor: C/EBPbeta; motif: NATTGCRYAAYN; match class: 1 0.0257705834467219 374 24 4 0.166666666666667 0.0106951871657754
TF TF:M03547 Factor: ER-alpha; motif: TGACCYN 0.0257705834467219 4712 9 7 0.777777777777778 0.00148556876061121
TF TF:M10003 Factor: NF-kappaB1; motif: AGGGAAAK 0.0257705834467219 1983 122 24 0.19672131147541 0.0121028744326778
TF TF:M04434 Factor: RAX2; motif: NYAATTAN 0.0270120820103864 2944 75 22 0.293333333333333 0.00747282608695652
TF TF:M04855_1 Factor: IRF-4; motif: AAGTTTC; match class: 1 0.0270120820103864 2009 121 24 0.198347107438017 0.0119462419113987
TF TF:M11559 Factor: FKHL14; motif: NYAMAYAAACAN 0.0272485019161087 2701 47 15 0.319148936170213 0.00555349870418364
TF TF:M04514_1 Factor: CPEB1; motif: AATAAAAA; match class: 1 0.0274322750756591 1113 66 11 0.166666666666667 0.00988319856244385
TF TF:M00339_1 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS; match class: 1 0.0275185208081249 1466 51 11 0.215686274509804 0.00750341064120055
TF TF:M11626_1 Factor: Sox-9; motif: NNNACAATRG; match class: 1 0.0275185208081249 1612 61 13 0.213114754098361 0.00806451612903226
TF TF:M11570 Factor: HNF-3alpha; motif: CNYTAAGTAAACAAAN 0.0275185208081249 3651 6 5 0.833333333333333 0.00136948781155848
TF TF:M07080 Factor: C/EBPbeta; motif: KATTGCAYMAY 0.0275185208081249 2026 100 21 0.21 0.010365251727542
TF TF:M04433 Factor: PRRX2; motif: NYAATTAN 0.0275185208081249 3153 75 23 0.306666666666667 0.00729464002537266
TF TF:M00912 Factor: C/EBP; motif: NTTRCNNAANNN 0.0276190560937523 4968 140 52 0.371428571428571 0.0104669887278583
TF TF:M10924 Factor: Gscl; motif: NTAATCCN 0.0276190560937523 6815 79 41 0.518987341772152 0.00601614086573734
TF TF:M04202 Factor: CEBPD; motif: RTTRCGCAAY 0.0277448810446533 5031 20 12 0.6 0.00238521168753727
TF TF:M07254_1 Factor: Foxc1; motif: TTVYTTTNW; match class: 1 0.0294012847266042 2610 22 9 0.409090909090909 0.00344827586206897
TF TF:M00006 Factor: MEF-2A; motif: CTCTAAAAATAACYCY 0.029612225355674 1986 18 7 0.388888888888889 0.00352467270896274
TF TF:M07466_1 Factor: Six-1; motif: CTCARRTTWCN; match class: 1 0.0297200485481704 413 23 4 0.173913043478261 0.00968523002421308
TF TF:M11248 Factor: Luman; motif: GRTGAYGTCAYN 0.0297200485481704 305 52 5 0.0961538461538462 0.0163934426229508
TF TF:M04354_1 Factor: HOXC11; motif: NGYMATAAAAN; match class: 1 0.0297640174274068 339 47 5 0.106382978723404 0.0147492625368732
TF TF:M04202_1 Factor: CEBPD; motif: RTTRCGCAAY; match class: 1 0.0297640174274068 1980 110 22 0.2 0.0111111111111111
TF TF:M04306 Factor: DPRX; motif: NNGGATTANN 0.0300452373011794 4886 60 26 0.433333333333333 0.00532132623823168
TF TF:M09911_1 Factor: c-Ets-1; motif: NNRCMGGAAGTGG; match class: 1 0.0303491784191914 208 45 4 0.0888888888888889 0.0192307692307692
TF TF:M01836 Factor: GR; motif: CNNNNTGTYCTNN 0.0304406221913216 5942 36 20 0.555555555555556 0.00336587007741501
TF TF:M09959 Factor: IRF-4; motif: NAANGRGGAASTGAAASN 0.0304406221913216 3386 28 12 0.428571428571429 0.00354400472533963
TF TF:M11697_1 Factor: MEF-2B1; motif: CCNWATWNRG; match class: 1 0.0304406221913216 683 7 3 0.428571428571429 0.00439238653001464
TF TF:M06132 Factor: ZNF823; motif: NYYACCAGCCCT 0.0304406221913216 55 77 3 0.038961038961039 0.0545454545454545
TF TF:M03557 Factor: P50; motif: GGRRANTCCCNN 0.0304406221913216 4967 115 44 0.382608695652174 0.0088584658747735
TF TF:M00291_1 Factor: Freac-3; motif: NNNNNGTAAATAAACA; match class: 1 0.0309181280426376 1096 79 12 0.151898734177215 0.0109489051094891
TF TF:M04236 Factor: FOXC2; motif: RTAAAYAAACA 0.0310306336112544 576 128 11 0.0859375 0.0190972222222222
TF TF:M08202 Factor: CDP:HOXB13; motif: SYMRTAAANATYGATY 0.0311076437400219 4079 78 28 0.358974358974359 0.00686442755577347
TF TF:M10046_1 Factor: c-Rel; motif: NRNRGGGRAATKCCA; match class: 1 0.0311459733434412 734 72 9 0.125 0.0122615803814714
TF TF:M01281_1 Factor: NFATc2; motif: GGAAAA; match class: 1 0.0311459733434412 11109 73 54 0.73972602739726 0.00486092357547934
TF TF:M01886_1 Factor: NFATc3; motif: GGAAAA; match class: 1 0.0311459733434412 11109 73 54 0.73972602739726 0.00486092357547934
TF TF:M03555_1 Factor: NFATc2; motif: GGAAAA; match class: 1 0.0311459733434412 11109 73 54 0.73972602739726 0.00486092357547934
TF TF:M10963 Factor: RHOXF1; motif: NGGATCAN 0.0311459733434412 2641 128 30 0.234375 0.011359333585763
TF TF:M04619 Factor: MTF-1; motif: CCGNGTGCAV 0.0314743533750326 1167 22 6 0.272727272727273 0.0051413881748072
TF TF:M11727 Factor: NF-1B; motif: NTTGGCNNNNTGCCARN 0.0316158342683107 75 58 3 0.0517241379310345 0.04
TF TF:M08469 Factor: Fli-1:C/EBPdelta; motif: NNCGGAWATTGCGCAAT 0.0316388018925053 6743 144 67 0.465277777777778 0.00993623016461516
TF TF:M11588 Factor: FOXK1; motif: NWYGTAAAYAR 0.0316388018925053 5352 53 25 0.471698113207547 0.0046711509715994
TF TF:M01211 Factor: PARP; motif: YDRGAAAWAS 0.0316430018240395 2634 5 4 0.8 0.00151860288534548
TF TF:M09930_1 Factor: foxm1; motif: TGTTTRCTYWNN; match class: 1 0.0317778245781628 1545 23 7 0.304347826086957 0.00453074433656958
TF TF:M01107 Factor: RUSH-1alpha; motif: NNMCWTNKNN 0.0322790856977274 3108 23 10 0.434782608695652 0.00321750321750322
TF TF:M08805 Factor: EAR2; motif: NCTYTGACCTN 0.0323581591367301 1027 25 6 0.24 0.00584225900681597
TF TF:M09625 Factor: GR; motif: RGNACANKNTGTNCY 0.0323581591367301 9274 58 39 0.672413793103448 0.00420530515419452
TF TF:M00054 Factor: NF-kappaB; motif: GGGAMTTYCC 0.0323581591367301 2444 53 15 0.283018867924528 0.00613747954173486
TF TF:M01408 Factor: Brn-3c; motif: NNTTATTAATKANKNC 0.0323581591367301 4888 98 38 0.387755102040816 0.00777414075286416
TF TF:M11286_1 Factor: Fra-1; motif: NATGAWTCAYN; match class: 1 0.0324479761973902 2340 72 18 0.25 0.00769230769230769
TF TF:M03816_1 Factor: c-MAF; motif: CNNNCTCAGCA; match class: 1 0.0324479761973902 1059 129 16 0.124031007751938 0.0151085930122757
TF TF:M00023 Factor: HOXA5; motif: TGCNHNCWYCCYCATTAKTGNDCNMNHYCN 0.0324479761973902 3491 134 38 0.283582089552239 0.0108851331996563
TF TF:M10818_1 Factor: HOXC11; motif: NGYMATAAAAN; match class: 1 0.0324479761973902 95 47 3 0.0638297872340425 0.0315789473684211
TF TF:M08899 Factor: SOX; motif: NNNNCWTTGTT 0.0324479761973902 2066 6 4 0.666666666666667 0.00193610842207164
TF TF:M01224 Factor: P50:RELA-P65; motif: GGANTTYCCCWN 0.0328088033117937 2329 139 29 0.20863309352518 0.0124516960068699
TF TF:M07988 Factor: EMX1; motif: NNTAATKANN 0.0329846520565743 3512 103 31 0.300970873786408 0.00882687927107061
TF TF:M09855_1 Factor: FOXP1; motif: CTGTTTNYTYTKN; match class: 1 0.0337662370363425 2166 103 22 0.213592233009709 0.0101569713758079
TF TF:M00953 Factor: AR; motif: NNNGNRRGNACANNGTGTTCTNNNNNN 0.0337662370363425 2415 54 15 0.277777777777778 0.0062111801242236
TF TF:M04279_1 Factor: ALX3; motif: NNYAATTANN; match class: 1 0.0337662370363425 1952 79 17 0.215189873417722 0.00870901639344262
TF TF:M07417_1 Factor: Elf-1; motif: NNCAGGAAGNNN; match class: 1 0.0337813367082345 102 45 3 0.0666666666666667 0.0294117647058824
TF TF:M09855 Factor: FOXP1; motif: CTGTTTNYTYTKN 0.0346862166781403 7645 105 56 0.533333333333333 0.00732504905166776
TF TF:M07429 Factor: SMAD3; motif: CAGACAS 0.035142612125129 6273 26 16 0.615384615384615 0.00255061374143153
TF TF:M11363 Factor: c-MAF; motif: NTGCTGACNNWGCA 0.0358210374891163 422 81 7 0.0864197530864197 0.0165876777251185
TF TF:M00774_1 Factor: NF-kappaB; motif: NGGGANTTYCCMNNNN; match class: 1 0.0359026527553053 192 53 4 0.0754716981132075 0.0208333333333333
TF TF:M07375 Factor: BCL-6; motif: TTCCTAGAAA 0.0359026527553053 556 117 10 0.0854700854700855 0.0179856115107914
TF TF:M00348 Factor: GATA-2; motif: NNWGATAASA 0.0360544236310184 2155 6 4 0.666666666666667 0.00185614849187935
TF TF:M00289_1 Factor: HFH3; motif: KNNTRTTTRTTTA; match class: 1 0.0360544236310184 817 43 7 0.162790697674419 0.00856793145654835
TF TF:M00065 Factor: Tal-1beta:E47; motif: NNNAACAGATGKTNNN 0.0360544236310184 1384 74 13 0.175675675675676 0.00939306358381503
TF TF:M07121 Factor: Blimp-1; motif: NRAAAGTGAAAGTNN 0.0360544236310184 401 135 9 0.0666666666666667 0.0224438902743142
TF TF:M08295 Factor: FOXO1A:Elf-1; motif: NAGAAAACCGAANM 0.0362113896519055 11711 53 42 0.792452830188679 0.00358637178720861
TF TF:M00195 Factor: Oct-1; motif: NNNNATGCAAATNAN 0.036305931485634 3659 121 36 0.297520661157025 0.00983875375785734
TF TF:M01107_1 Factor: RUSH-1alpha; motif: NNMCWTNKNN; match class: 1 0.036305931485634 385 13 3 0.230769230769231 0.00779220779220779
TF TF:M11387 Factor: elf5; motif: NNNNMGGAAGTN 0.036305931485634 2598 104 25 0.240384615384615 0.00962278675904542
TF TF:M01260_1 Factor: STAT1; motif: NNTTTCYNGGAARNNNNNNNNN; match class: 1 0.036305931485634 657 117 11 0.094017094017094 0.0167427701674277
TF TF:M00133_1 Factor: Tst-1; motif: NNKGAATTAVAVTDN; match class: 1 0.036305931485634 1298 21 6 0.285714285714286 0.00462249614791988
TF TF:M00192 Factor: GR; motif: NNNNNNCNNTNTGTNCTNN 0.036305931485634 7611 36 23 0.638888888888889 0.00302194192615951
TF TF:M00794 Factor: TTF-1; motif: NNNNCAAGNRNN 0.036305931485634 4679 144 50 0.347222222222222 0.0106860440265014
TF TF:M07379 Factor: c-Ets-2; motif: NNCTTCCTNNN 0.0365312971289607 3487 75 24 0.32 0.00688270719816461
TF TF:M04849_1 Factor: RelA-p65; motif: AAASTCCC; match class: 1 0.0369478436105752 1170 31 7 0.225806451612903 0.00598290598290598
TF TF:M12188_1 Factor: KLF17; motif: NGMCMCRCCCTN; match class: 1 0.0370467787644913 588 112 10 0.0892857142857143 0.0170068027210884
TF TF:M08471 Factor: Fli-1:HOXB13; motif: NNCGGAARYNRTWAA 0.0375581637049886 5224 9 7 0.777777777777778 0.00133996937212864
TF TF:M08881 Factor: ETSLIKE; motif: NACTTCCTNN 0.0376581925904836 3140 56 18 0.321428571428571 0.00573248407643312
TF TF:M11209_1 Factor: AP-4; motif: ANCATATGNT; match class: 1 0.037847518381139 2803 72 20 0.277777777777778 0.00713521227256511
TF TF:M08215 Factor: Elk-1:EVX1; motif: NNCGGWAATNNYMATTA 0.037847518381139 6557 69 35 0.507246376811594 0.00533780692389812
TF TF:M00513 Factor: ATF3; motif: CBCTGACGTCANCS 0.0381514444127013 6386 56 29 0.517857142857143 0.00454118383964923
TF TF:M01023 Factor: HSF1; motif: NTTCTRGAAVNTTCTYM 0.0381514444127013 2721 144 33 0.229166666666667 0.0121278941565601
TF TF:M04360_1 Factor: HOXD11; motif: NNYMATAAAA; match class: 1 0.0381514444127013 1048 54 9 0.166666666666667 0.00858778625954199
TF TF:M04254 Factor: FOXL1; motif: NRTAAAYAAACAN 0.0381514444127013 606 128 11 0.0859375 0.0181518151815182
TF TF:M10565 Factor: Msx-1; motif: NCAATTAN 0.0381514444127013 2399 101 23 0.227722772277228 0.00958732805335557
TF TF:M04292 Factor: BSX; motif: NYNATTAN 0.0381514444127013 2399 101 23 0.227722772277228 0.00958732805335557
TF TF:M07270 Factor: TEF-3; motif: GNTATTTTT 0.0382809788453874 10215 79 54 0.683544303797468 0.0052863436123348
TF TF:M10092 Factor: TEF-1; motif: RCATTCCWGNNN 0.0382809788453874 3195 27 11 0.407407407407407 0.00344287949921753
TF TF:M00672 Factor: TEF; motif: ATGTTWAYATAA 0.0382809788453874 5921 73 34 0.465753424657534 0.00574227326465124
TF TF:M05445 Factor: GATA-5; motif: TTAMCAR 0.0382809788453874 3283 54 18 0.333333333333333 0.00548279013097776
TF TF:M03865_1 Factor: Blimp-1; motif: NRGRAAGKGAAAGK; match class: 1 0.0382809788453874 45 111 3 0.027027027027027 0.0666666666666667
TF TF:M11360 Factor: c-MAF; motif: NTGCTGACNNNGCR 0.0382809788453874 221 117 6 0.0512820512820513 0.0271493212669683
TF TF:M10081 Factor: STAT3; motif: NNYTTCCMRGAA 0.0385184121484572 3621 123 36 0.292682926829268 0.00994200497100249
TF TF:M11445_1 Factor: Elf-1; motif: NANCAGGAAGTR; match class: 1 0.039203702334386 83 129 4 0.0310077519379845 0.0481927710843374
TF TF:M12333 Factor: ZBTB20; motif: NNAAYGTATRKN 0.039203702334386 2707 123 29 0.235772357723577 0.0107129663834503
TF TF:M08822_1 Factor: Msx-1; motif: WNGNAATTANV; match class: 1 0.0393654912626754 2272 6 4 0.666666666666667 0.00176056338028169
TF TF:M11568 Factor: HNF-3alpha; motif: NNYTAWGTAAACAAAN 0.0395860765987651 2277 6 4 0.666666666666667 0.00175669740887132
TF TF:M09625_1 Factor: GR; motif: RGNACANKNTGTNCY; match class: 1 0.0396590932011891 4205 57 22 0.385964912280702 0.00523186682520809
TF TF:M09874 Factor: BCL-6; motif: NNCTTTCYAGGAA 0.0396590932011891 2807 119 29 0.243697478991597 0.0103313145707161
TF TF:M04822 Factor: c-ets-1; motif: GGAGTTG 0.0397834945732107 5496 32 17 0.53125 0.00309315866084425
TF TF:M10019 Factor: OLIG2; motif: CCAKCTGYTYNYNNNNNN 0.0397834945732107 3868 116 36 0.310344827586207 0.0093071354705274
TF TF:M04750_1 Factor: GR; motif: RGRACATTNTGTYC; match class: 1 0.0402026688278395 1704 12 5 0.416666666666667 0.00293427230046948
TF TF:M01653 Factor: HMGIY; motif: NGWWATTN 0.0402026688278395 6100 95 43 0.452631578947368 0.00704918032786885
TF TF:M03886 Factor: Sox-2; motif: NNCCWTTGTTNTKN 0.0402026688278395 993 6 3 0.5 0.00302114803625378
TF TF:M07301 Factor: NFATc4; motif: NGGAAAAN 0.0404646854511435 4070 66 24 0.363636363636364 0.0058968058968059
TF TF:M08461 Factor: Erm:EVX1; motif: NNCGGAAATKR 0.0406712497456048 3396 19 9 0.473684210526316 0.00265017667844523
TF TF:M03545 Factor: c-Rel; motif: NGGGAATYTCCN 0.0407737983454631 5530 53 25 0.471698113207547 0.00452079566003617
TF TF:M10042_1 Factor: PR; motif: RGNACATTYTGTNCTN; match class: 1 0.0407737983454631 998 12 4 0.333333333333333 0.00400801603206413
TF TF:M01012 Factor: HNF3; motif: NNNNNTRTTTRYTYWNKN 0.0414623599452486 2298 22 8 0.363636363636364 0.00348128807658834
TF TF:M01884_1 Factor: IRF-7; motif: AAGWGAA; match class: 1 0.0414623599452486 4556 135 46 0.340740740740741 0.0100965759438104
TF TF:M10640_1 Factor: CSX; motif: NCCACTTRAN; match class: 1 0.0414623599452486 1237 10 4 0.4 0.00323362974939369
TF TF:M08888 Factor: MAFB; motif: NTCAGCN 0.0415688880215711 10140 140 89 0.635714285714286 0.00877712031558185
TF TF:M08907_1 Factor: AR; motif: AGAACANNNTGTTCT; match class: 1 0.0418810844549913 2176 50 13 0.26 0.00597426470588235
TF TF:M01808 Factor: NMYC; motif: CAYCTG 0.0418810844549913 12944 59 49 0.830508474576271 0.00378553770086527
TF TF:M03813_1 Factor: BRN1; motif: HAATGCN; match class: 1 0.0418871834086463 7077 72 38 0.527777777777778 0.00536950685318638
TF TF:M04802 Factor: c-Fos; motif: ACTCACCA 0.0421081593743279 7386 128 64 0.5 0.00866504197129705
TF TF:M03872 Factor: HNF-1beta; motif: GTTAATYATTAACY 0.0421306019148706 4145 76 27 0.355263157894737 0.00651387213510253
TF TF:M03579 Factor: PEA3; motif: AGGAAGT 0.042164352819053 6837 58 31 0.53448275862069 0.00453415240602603
TF TF:M06481 Factor: ZNF433; motif: AAMCTGATGMCA 0.042164352819053 44 121 3 0.0247933884297521 0.0681818181818182
TF TF:M07064 Factor: STAT1; motif: TTCNRGGAAN 0.042164352819053 2606 123 28 0.227642276422764 0.0107444359171144
TF TF:M07382 Factor: Fli-1; motif: MGGAAGT 0.042164352819053 6837 58 31 0.53448275862069 0.00453415240602603
TF TF:M08482 Factor: FOXO1A:HOXA10; motif: RWMAACANCRTWAA 0.042164352819053 4206 54 21 0.388888888888889 0.00499286733238231
TF TF:M01870 Factor: C-ets-1; motif: AGGAAGN 0.042164352819053 6837 58 31 0.53448275862069 0.00453415240602603
TF TF:M02278 Factor: SPI1; motif: AGGAAGT 0.042164352819053 6837 58 31 0.53448275862069 0.00453415240602603
TF TF:M01595 Factor: STAT3; motif: NNTTCCRGGAANNNNN 0.042164352819053 7736 88 48 0.545454545454545 0.0062047569803516
TF TF:M11549 Factor: HFH-1; motif: YTANRTAAACWN 0.0421675672853781 839 96 11 0.114583333333333 0.0131108462455304
TF TF:M07421 Factor: HOXC-8; motif: GAATWAYARN 0.0427998295420725 1504 55 11 0.2 0.00731382978723404
TF TF:M02116_1 Factor: Sox-10; motif: NACAAWG; match class: 1 0.042821831044917 8039 104 57 0.548076923076923 0.00709043413359871
TF TF:M00340_1 Factor: c-Ets; motif: KRCAGGAARTRNKT; match class: 1 0.042821831044917 906 116 13 0.112068965517241 0.0143487858719647
TF TF:M00432 Factor: TTF1; motif: ASTCAAGTRK 0.0433337378105857 5394 122 48 0.39344262295082 0.00889877641824249
TF TF:M11383_1 Factor: ESE-1; motif: ACCAGGAAGTANNNNNNNAAWAA; match class: 1 0.043338394495662 589 80 8 0.1 0.0135823429541596
TF TF:M10074 Factor: Spi-B; motif: NRAAAGAGGAAGTGARA 0.043338394495662 1611 142 22 0.154929577464789 0.0136561142147734
TF TF:M00926 Factor: AP-1; motif: TGAGTCAN 0.0437029413379206 924 52 8 0.153846153846154 0.00865800865800866
TF TF:M01267 Factor: Fra-1; motif: TGAGTCAN 0.0437029413379206 924 52 8 0.153846153846154 0.00865800865800866
TF TF:M00423 Factor: FOXJ2; motif: AYMATAATATTTKN 0.0437029413379206 6970 55 30 0.545454545454545 0.00430416068866571
TF TF:M01307 Factor: Oct3; motif: NATGCAANNN 0.0437029413379206 3986 23 11 0.478260869565217 0.00275965880582037
TF TF:M11290_1 Factor: ATF-3; motif: NATGATGTCATN; match class: 1 0.0437029413379206 1872 79 16 0.20253164556962 0.00854700854700855
TF TF:M08926 Factor: JUNB; motif: ATGACTCA 0.0437029413379206 924 52 8 0.153846153846154 0.00865800865800866
TF TF:M10713_1 Factor: HOXD4; motif: RTCRTTAN; match class: 1 0.0437029413379206 616 77 8 0.103896103896104 0.012987012987013
TF TF:M04305 Factor: DMBX1; motif: NNGGATTANN 0.0437029413379206 5134 60 26 0.433333333333333 0.00506427736657577
TF TF:M04054_1 Factor: NF-kappaB; motif: AGGGGAWTCCCCT; match class: 1 0.0439026259808883 1295 30 7 0.233333333333333 0.00540540540540541
TF TF:M09635 Factor: MafK; motif: NAAWNTGCTGASTCAGCANWWN 0.0439026259808883 68 81 3 0.037037037037037 0.0441176470588235
TF TF:M04415 Factor: NKX6-1; motif: NTMATTAA 0.04391264849858 1846 66 14 0.212121212121212 0.0075839653304442
TF TF:M00095_1 Factor: CDP; motif: CCAATAATCGAT; match class: 1 0.0442218110715789 2983 99 26 0.262626262626263 0.00871605766007375
TF TF:M00205 Factor: GR; motif: GGTACAANNTGTYCTK 0.0443972012059103 6653 55 29 0.527272727272727 0.00435893581842778
TF TF:M11908_1 Factor: POU3F2; motif: TAATKAGNNNNTAATKA; match class: 1 0.0444982264234007 1278 23 6 0.260869565217391 0.00469483568075117
TF TF:M11696_1 Factor: MEF-2B1; motif: CCNWATWWRG; match class: 1 0.0447789378692664 898 7 3 0.428571428571429 0.00334075723830735
TF TF:M11983 Factor: NFATc2; motif: NTTTCCGCGGAAAN 0.0454119805208158 8048 69 40 0.579710144927536 0.00497017892644135
TF TF:M07065 Factor: STAT3; motif: TTCYGGGAAN 0.0459454853858555 4948 123 45 0.365853658536585 0.00909458367016977
TF TF:M07104 Factor: JunD; motif: NRTGASTCATN 0.0459454853858555 2675 52 15 0.288461538461538 0.00560747663551402
TF TF:M00224_1 Factor: STAT1; motif: NNNSANTTCCGGGAANTGNSN; match class: 1 0.0459454853858555 2710 98 24 0.244897959183673 0.00885608856088561
TF TF:M10814 Factor: HOXC11; motif: NGYMATAAAAN 0.0459454853858555 756 64 8 0.125 0.0105820105820106
TF TF:M01884 Factor: IRF-7; motif: AAGWGAA 0.0459454853858555 10868 121 82 0.677685950413223 0.00754508649245491
TF TF:M04224 Factor: NRL; motif: NNNNTGCTGAC 0.046013720666635 4667 123 43 0.349593495934959 0.00921362759802871
TF TF:M06005 Factor: ZSCAN11; motif: NYMKAGGAAASA 0.046013720666635 311 90 6 0.0666666666666667 0.0192926045016077
TF TF:M03882_1 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC; match class: 1 0.046013720666635 714 115 11 0.0956521739130435 0.015406162464986
TF TF:M04233 Factor: FOXC1; motif: NGTMAATATTKACN 0.046013720666635 114 103 4 0.0388349514563107 0.0350877192982456
TF TF:M09839 Factor: ATF4; motif: ATTGCATCAT 0.046013720666635 2145 46 12 0.260869565217391 0.00559440559440559
TF TF:M07417 Factor: Elf-1; motif: NNCAGGAAGNNN 0.046013720666635 1774 107 19 0.177570093457944 0.0107102593010147
TF TF:M02377_1 Factor: ESR2; motif: NNRGGTCANNNTGMCCTN; match class: 1 0.046063088387841 690 9 3 0.333333333333333 0.00434782608695652
TF TF:M11334 Factor: ATF-4; motif: GGATGATGTCATCC 0.0466338201104689 6386 16 11 0.6875 0.00172251800814281
TF TF:M08890 Factor: MYB; motif: NNAACTGN 0.0466338201104689 1355 139 19 0.136690647482014 0.0140221402214022
TF TF:M07268_1 Factor: Sox-4; motif: BCWTTGT; match class: 1 0.0466540395351024 1086 66 10 0.151515151515152 0.00920810313075507
TF TF:M11431 Factor: PEA3; motif: NTCGTAAATGCA 0.0468521669398452 10559 86 59 0.686046511627907 0.00558765034567667
TF TF:M01308_1 Factor: Sox-4; motif: AACAAWGR; match class: 1 0.0469078232840993 107 54 3 0.0555555555555556 0.0280373831775701
TF TF:M02080 Factor: Isl2; motif: YTAAGTG 0.0470019115088098 6041 144 60 0.416666666666667 0.0099321304419798
TF TF:M09959_1 Factor: IRF-4; motif: NAANGRGGAASTGAAASN; match class: 1 0.0470960254768766 395 72 6 0.0833333333333333 0.0151898734177215
TF TF:M09618 Factor: HNF-3alpha; motif: NTRTTTACWYWNN 0.0474364637464237 2353 59 15 0.254237288135593 0.00637484062898428
TF TF:M04078 Factor: POU3F2; motif: NWTGCATAAWTTA 0.0474364637464237 3944 62 22 0.354838709677419 0.00557809330628803
TF TF:M04476_1 Factor: NR3C1; motif: NRGWACAYNRTGTWCYN; match class: 1 0.0476264301129285 5349 121 47 0.388429752066116 0.0087866891007665
TF TF:M04399 Factor: MEOX2; motif: NSTAATTANN 0.0478085977629644 3837 103 32 0.310679611650485 0.00833984884023977
TF TF:M00158 Factor: COUP-TF,; motif: TGAMCTTTGMMCYT 0.0480679096736997 2215 133 26 0.195488721804511 0.0117381489841986
TF TF:M00955 Factor: GR; motif: NNNNNNNGKACNNNNTGTTCTNNNNNN 0.0480679096736997 4958 36 17 0.472222222222222 0.00342880193626462
TF TF:M08907 Factor: AR; motif: AGAACANNNTGTTCT 0.0480679096736997 2256 50 13 0.26 0.00576241134751773
TF TF:M08369 Factor: HOXD12:PEA3; motif: RCCGGAAGTAATAAAM 0.0480679096736997 4596 6 5 0.833333333333333 0.00108790252393386
TF TF:M03996 Factor: SPIC; motif: NAAAAGMGGAAGTA 0.0480679096736997 670 124 11 0.0887096774193548 0.0164179104477612
TF TF:M01292 Factor: HOXA13; motif: ATAAMA 0.0480679096736997 13416 79 65 0.822784810126582 0.00484496124031008
TF TF:M04340 Factor: HOXA10; motif: NGYMATAAAAN 0.0480679096736997 1978 21 7 0.333333333333333 0.00353892821031345
TF TF:M04077 Factor: POU3F1; motif: WTGMATAAWTNA 0.0480679096736997 2836 105 26 0.247619047619048 0.00916784203102962
TF TF:M08931 Factor: JUND:FRA-2; motif: NATGACTCAT 0.0480679096736997 1410 52 10 0.192307692307692 0.00709219858156028
TF TF:M10541 Factor: SUHW1; motif: TCTCTCCAGTRTGAATTCTCTGAT 0.0480679096736997 7303 80 42 0.525 0.00575106120772285
TF TF:M08976_1 Factor: SRY; motif: AACAATNR; match class: 1 0.0482706269799117 8093 63 37 0.587301587301587 0.00457185221796614
TF TF:M00746 Factor: Elf-1; motif: RNWMBAGGAART 0.0482706269799117 3365 72 22 0.305555555555556 0.00653789004457652
TF TF:M02025_1 Factor: MEF-2C; motif: TATTTWT; match class: 1 0.0482762056652641 7743 25 17 0.68 0.00219553144775927
TF TF:M07047_1 Factor: Lhx2; motif: WATTAN; match class: 1 0.0482762056652641 4624 6 5 0.833333333333333 0.00108131487889273
TF TF:M08003_1 Factor: POU6F1; motif: ANTAATTANT; match class: 1 0.0484830983536778 525 12 3 0.25 0.00571428571428571
TF TF:M08003 Factor: POU6F1; motif: ANTAATTANT 0.0484830983536778 525 12 3 0.25 0.00571428571428571
TF TF:M00925 Factor: AP-1; motif: NTGACTCAN 0.0485683584394179 2554 134 29 0.216417910447761 0.0113547376664056
TF TF:M11983_1 Factor: NFATc2; motif: NTTTCCGCGGAAAN; match class: 1 0.0489270649617097 7294 69 37 0.536231884057971 0.00507266246229778
TF TF:M07204_1 Factor: AR; motif: ARGAACANNNTGTNC; match class: 1 0.0489270649617097 963 52 8 0.153846153846154 0.0083073727933541
TF TF:M01869 Factor: C/EBPgamma; motif: NRTKRSRMAAKN 0.0491081991016935 3194 99 27 0.272727272727273 0.0084533500313087
TF TF:M04453_1 Factor: AR; motif: RGGWACAYNGTGTWCYN; match class: 1 0.0491413086131068 3794 57 20 0.350877192982456 0.00527148128624143
TF TF:M02108 Factor: CSX; motif: NNCACTTGNRN 0.0492143858748774 7061 135 64 0.474074074074074 0.00906387197280838
TF TF:M08575 Factor: GCMa:C/EBPbeta; motif: ATGCGGGTNNRTTGCGCAAY 0.0492143858748774 7026 17 12 0.705882352941177 0.00170794192997438
TF TF:M09725_1 Factor: DREF; motif: CTYYCWCTTCCY; match class: 1 0.0492508454625437 2061 136 25 0.183823529411765 0.0121300339640951
TF TF:M10673 Factor: Emx-2; motif: YTAATTAN 0.0493452098728638 3224 103 28 0.271844660194175 0.0086848635235732
TF TF:M04446 Factor: VAX1; motif: YTAATTAN 0.0493452098728638 3224 103 28 0.271844660194175 0.0086848635235732
TF TF:M10021 Factor: Otx2; motif: NRRGGATTARN 0.0493452098728638 1679 59 12 0.203389830508475 0.00714711137581894
TF TF:M11909_1 Factor: POU3F2; motif: NTATGCWAATKAG; match class: 1 0.0493452098728638 1184 72 11 0.152777777777778 0.00929054054054054
TF TF:M01149 Factor: DMRT4; motif: AATGTADCAAWTT 0.0494545639871605 1842 61 13 0.213114754098361 0.00705754614549403
TF TF:M00776_1 Factor: SREBP; motif: VNNVTCACCCYA; match class: 1 0.0494696119461393 1289 76 12 0.157894736842105 0.00930954228083786
TF TF:M11632_1 Factor: Sox-10; motif: AACAATRGNCYATTGTT; match class: 1 0.0497356413315427 4639 67 26 0.388059701492537 0.00560465617589998
WP WP:WP619 Type II interferon signaling (IFNG) 3.06220195272461e-16 37 68 13 0.191176470588235 0.351351351351351
WP WP:WP4197 The human immune response to tuberculosis 4.89265162031772e-13 23 115 11 0.0956521739130435 0.478260869565217
WP WP:WP4880 Host-pathogen interaction of human corona viruses - Interferon induction 8.37497563492182e-08 33 84 8 0.0952380952380952 0.242424242424242
WP WP:WP4868 Type I Interferon Induction and Signaling During SARS-CoV-2 Infection 3.69960136800606e-06 29 63 6 0.0952380952380952 0.206896551724138
WP WP:WP5039 SARS-CoV-2 Innate Immunity Evasion and Cell-specific immune response 1.95508104475663e-05 68 84 8 0.0952380952380952 0.117647058823529
WP WP:WP4341 Non-genomic actions of 1,25 dihydroxyvitamin D3 0.000354835319487682 70 35 5 0.142857142857143 0.0714285714285714
WP WP:WP4705 Pathways of nucleic acid metabolism and innate immune sensing 0.000461369817014912 16 84 4 0.0476190476190476 0.25
WP WP:WP4912 SARS coronavirus and innate immunity 0.00491939753750522 31 84 4 0.0476190476190476 0.129032258064516
WP WP:WP4877 Host-pathogen interaction of human corona viruses - MAPK signaling 0.0117886016179128 36 41 3 0.0731707317073171 0.0833333333333333
WP WP:WP183 Proteasome Degradation 0.0206594219133776 64 104 5 0.0480769230769231 0.078125
WP WP:WP3929 Chemokine signaling pathway 0.0332333609996534 165 91 7 0.0769230769230769 0.0424242424242424
WP WP:WP2328 Allograft Rejection 0.049185345581961 88 104 5 0.0480769230769231 0.0568181818181818

pM21 transcription factor target enrichment of top program genes

TF enrichment of pM21
TFs corrosponding to activation of pM21. (Left) pearson correlation of TF expression and gene expression program activatity in Myeloid cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.