pS05 program activity among Stromal cells

Activation of pS05
pS05 gene program activation in Stromal cells.
Gene program activation of pS05 by different cell subtypes
pS05 gene program activation among cells of different subtypes (Stromal cells).

pS05 top program genes

Top genes of pS05 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pS05 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pS05
pS05 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:60 Interferon-stimulated gene factor 3 transcription complex ISGF3 0.000488119162201476 3 98 3 0.0306122448979592 1
CORUM CORUM:7385 DTX3L-PARP9-STAT1 complex 0.000488119162201476 3 80 3 0.0375 1
GO:BP GO:0060337 type I interferon signaling pathway 9.46165143127542e-50 95 74 31 0.418918918918919 0.326315789473684
GO:BP GO:0071357 cellular response to type I interferon 9.46165143127542e-50 96 74 31 0.418918918918919 0.322916666666667
GO:BP GO:0034340 response to type I interferon 4.08066372013234e-49 101 74 31 0.418918918918919 0.306930693069307
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 1.02833204991054e-48 2255 109 82 0.752293577981651 0.0363636363636364
GO:BP GO:0098542 defense response to other organism 4.91076398138101e-48 1218 109 67 0.614678899082569 0.055008210180624
GO:BP GO:0043207 response to external biotic stimulus 5.91037644671118e-47 1594 109 72 0.660550458715596 0.0451693851944793
GO:BP GO:0051707 response to other organism 5.91037644671118e-47 1592 109 72 0.660550458715596 0.0452261306532663
GO:BP GO:0045087 innate immune response 7.14557886960157e-47 998 109 62 0.568807339449541 0.062124248496994
GO:BP GO:0009607 response to biotic stimulus 1.85105742352421e-46 1626 109 72 0.660550458715596 0.044280442804428
GO:BP GO:0051607 defense response to virus 1.22954841290447e-45 267 114 42 0.368421052631579 0.157303370786517
GO:BP GO:0140546 defense response to symbiont 1.22954841290447e-45 267 114 42 0.368421052631579 0.157303370786517
GO:BP GO:0006952 defense response 1.80314178691117e-44 1818 109 73 0.669724770642202 0.0401540154015402
GO:BP GO:0009615 response to virus 2.05502193225102e-44 364 114 45 0.394736842105263 0.123626373626374
GO:BP GO:0006955 immune response 2.9088686363267e-43 2311 109 78 0.715596330275229 0.033751622674167
GO:BP GO:0034097 response to cytokine 2.80565159629874e-38 1226 104 58 0.557692307692308 0.0473083197389886
GO:BP GO:0019221 cytokine-mediated signaling pathway 1.17370285858693e-36 810 123 53 0.430894308943089 0.0654320987654321
GO:BP GO:0071345 cellular response to cytokine stimulus 3.15867366946472e-35 1132 104 54 0.519230769230769 0.0477031802120141
GO:BP GO:0002376 immune system process 2.29896166384619e-34 3278 109 80 0.73394495412844 0.024405125076266
GO:BP GO:0002252 immune effector process 3.40433700755683e-33 1309 108 56 0.518518518518518 0.0427807486631016
GO:BP GO:0016032 viral process 7.01868725566002e-32 942 109 49 0.44954128440367 0.0520169851380042
GO:BP GO:0044403 biological process involved in symbiotic interaction 7.72447355108041e-32 1001 109 50 0.458715596330275 0.04995004995005
GO:BP GO:0009605 response to external stimulus 2.62097753518496e-30 2944 109 73 0.669724770642202 0.0247961956521739
GO:BP GO:0034341 response to interferon-gamma 1.10875960337448e-28 196 99 27 0.272727272727273 0.137755102040816
GO:BP GO:0048525 negative regulation of viral process 1.04748730991209e-27 94 89 21 0.235955056179775 0.223404255319149
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 1.42890436397382e-25 88 98 20 0.204081632653061 0.227272727272727
GO:BP GO:0050792 regulation of viral process 1.42890436397382e-25 192 101 25 0.247524752475248 0.130208333333333
GO:BP GO:0071346 cellular response to interferon-gamma 2.78503582797138e-25 175 99 24 0.242424242424242 0.137142857142857
GO:BP GO:0045071 negative regulation of viral genome replication 4.37135201385243e-25 54 89 17 0.191011235955056 0.314814814814815
GO:BP GO:0043903 regulation of biological process involved in symbiotic interaction 5.40859221801923e-25 203 101 25 0.247524752475248 0.123152709359606
GO:BP GO:1903900 regulation of viral life cycle 1.13703355281979e-24 153 89 22 0.247191011235955 0.143790849673203
GO:BP GO:0045069 regulation of viral genome replication 2.84695066919342e-23 84 89 18 0.202247191011236 0.214285714285714
GO:BP GO:0006950 response to stress 2.52982486314047e-22 4170 109 75 0.688073394495413 0.0179856115107914
GO:BP GO:0071310 cellular response to organic substance 3.21077381334625e-22 2776 104 61 0.586538461538462 0.0219740634005764
GO:BP GO:0019079 viral genome replication 3.1951352239367e-21 131 89 19 0.213483146067416 0.145038167938931
GO:BP GO:0002831 regulation of response to biotic stimulus 3.39711674801833e-21 415 109 29 0.26605504587156 0.0698795180722892
GO:BP GO:0010033 response to organic substance 4.65440310319926e-20 3412 74 52 0.702702702702703 0.0152403282532239
GO:BP GO:0019058 viral life cycle 3.04103007523063e-19 353 89 24 0.269662921348315 0.0679886685552408
GO:BP GO:0070887 cellular response to chemical stimulus 3.18875147905627e-18 3393 74 50 0.675675675675676 0.0147362216327734
GO:BP GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 2.10017032780254e-17 75 109 15 0.137614678899083 0.2
GO:BP GO:0045088 regulation of innate immune response 3.91599642987877e-17 309 109 23 0.211009174311927 0.0744336569579288
GO:BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 5.67384399061568e-17 80 109 15 0.137614678899083 0.1875
GO:BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.6889525775346e-16 99 118 16 0.135593220338983 0.161616161616162
GO:BP GO:0002483 antigen processing and presentation of endogenous peptide antigen 3.09627278259538e-16 19 65 9 0.138461538461538 0.473684210526316
GO:BP GO:0007166 cell surface receptor signaling pathway 3.34995873272659e-16 3210 48 36 0.75 0.011214953271028
GO:BP GO:0031347 regulation of defense response 5.2653440669382e-16 704 109 30 0.275229357798165 0.0426136363636364
GO:BP GO:0035455 response to interferon-alpha 8.47592929070388e-16 23 58 9 0.155172413793103 0.391304347826087
GO:BP GO:0019883 antigen processing and presentation of endogenous antigen 9.3962187471508e-15 26 65 9 0.138461538461538 0.346153846153846
GO:BP GO:0050776 regulation of immune response 1.9242219948134e-14 996 131 36 0.274809160305344 0.036144578313253
GO:BP GO:0002682 regulation of immune system process 2.60075866517716e-14 1617 131 45 0.343511450381679 0.0278293135435993
GO:BP GO:0042221 response to chemical 2.80181792027566e-14 4781 74 53 0.716216216216216 0.0110855469567036
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 7.01280396216166e-14 174 65 14 0.215384615384615 0.0804597701149425
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 1.29443625691638e-13 182 65 14 0.215384615384615 0.0769230769230769
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 2.68780990323307e-13 192 65 14 0.215384615384615 0.0729166666666667
GO:BP GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 2.88203248420045e-13 13 61 7 0.114754098360656 0.538461538461538
GO:BP GO:0032101 regulation of response to external stimulus 4.20881784086718e-13 1051 109 32 0.293577981651376 0.0304471931493815
GO:BP GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent 2.24381286276903e-12 8 65 6 0.0923076923076923 0.75
GO:BP GO:0001817 regulation of cytokine production 3.65196335691293e-12 806 131 30 0.229007633587786 0.0372208436724566
GO:BP GO:0019882 antigen processing and presentation 3.83043452846898e-12 234 65 14 0.215384615384615 0.0598290598290598
GO:BP GO:0045824 negative regulation of innate immune response 7.45016331680734e-12 66 108 11 0.101851851851852 0.166666666666667
GO:BP GO:0001816 cytokine production 1.14393099970161e-11 844 131 30 0.229007633587786 0.0355450236966825
GO:BP GO:0035456 response to interferon-beta 3.40672425808755e-11 30 137 9 0.0656934306569343 0.3
GO:BP GO:0002833 positive regulation of response to biotic stimulus 8.80212034947974e-11 250 109 16 0.146788990825688 0.064
GO:BP GO:0002684 positive regulation of immune system process 1.20001411430459e-10 1065 138 33 0.239130434782609 0.0309859154929577
GO:BP GO:0050778 positive regulation of immune response 1.68534123889467e-10 753 131 27 0.206106870229008 0.0358565737051793
GO:BP GO:0050896 response to stimulus 7.46569549358422e-10 9407 106 88 0.830188679245283 0.00935473583501648
GO:BP GO:0002832 negative regulation of response to biotic stimulus 7.46569549358422e-10 100 108 11 0.101851851851852 0.11
GO:BP GO:0000209 protein polyubiquitination 7.94084557411925e-10 342 124 18 0.145161290322581 0.0526315789473684
GO:BP GO:0032103 positive regulation of response to external stimulus 1.042902250996e-09 513 109 20 0.18348623853211 0.0389863547758285
GO:BP GO:0045089 positive regulation of innate immune response 1.62863388753683e-09 216 71 12 0.169014084507042 0.0555555555555556
GO:BP GO:0080134 regulation of response to stress 1.70772575545736e-09 1443 109 32 0.293577981651376 0.0221760221760222
GO:BP GO:0007165 signal transduction 1.95169518518551e-09 6309 48 39 0.8125 0.00618164526866381
GO:BP GO:0048584 positive regulation of response to stimulus 2.8341537826534e-09 2344 114 42 0.368421052631579 0.0179180887372014
GO:BP GO:0023052 signaling 3.43019165444323e-09 6810 48 40 0.833333333333333 0.00587371512481645
GO:BP GO:0001819 positive regulation of cytokine production 4.30222999643817e-09 452 119 19 0.159663865546218 0.0420353982300885
GO:BP GO:0002697 regulation of immune effector process 5.92834187602385e-09 461 119 19 0.159663865546218 0.0412147505422994
GO:BP GO:0051716 cellular response to stimulus 6.06786060826895e-09 7781 48 42 0.875 0.00539776378357538
GO:BP GO:0050777 negative regulation of immune response 1.74679658739849e-08 157 119 12 0.100840336134454 0.0764331210191083
GO:BP GO:0031349 positive regulation of defense response 1.76164240178529e-08 362 109 16 0.146788990825688 0.0441988950276243
GO:BP GO:0007154 cell communication 2.63568901888992e-08 6829 48 39 0.8125 0.00571093864401816
GO:BP GO:0032480 negative regulation of type I interferon production 3.06460480765949e-08 46 126 8 0.0634920634920635 0.173913043478261
GO:BP GO:0048519 negative regulation of biological process 3.06976350379195e-08 5757 48 36 0.75 0.00625325690463783
GO:BP GO:0009617 response to bacterium 3.06976350379195e-08 743 123 23 0.186991869918699 0.0309555854643338
GO:BP GO:0032479 regulation of type I interferon production 5.5206700809141e-08 130 126 11 0.0873015873015873 0.0846153846153846
GO:BP GO:0032606 type I interferon production 5.92028196334892e-08 131 126 11 0.0873015873015873 0.083969465648855
GO:BP GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib 7.09986659623021e-08 6 65 4 0.0615384615384615 0.666666666666667
GO:BP GO:0071356 cellular response to tumor necrosis factor 7.82455506293358e-08 306 123 15 0.121951219512195 0.0490196078431373
GO:BP GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent 1.24825838222665e-07 3 30 3 0.1 1
GO:BP GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway 1.24825838222665e-07 3 30 3 0.1 1
GO:BP GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 1.64672527515253e-07 16 78 5 0.0641025641025641 0.3125
GO:BP GO:0034612 response to tumor necrosis factor 2.16528865867853e-07 331 123 15 0.121951219512195 0.0453172205438066
GO:BP GO:0002716 negative regulation of natural killer cell mediated immunity 2.27393006193073e-07 17 78 5 0.0641025641025641 0.294117647058824
GO:BP GO:0098586 cellular response to virus 3.11840304907017e-07 72 108 8 0.0740740740740741 0.111111111111111
GO:BP GO:0038061 NIK/NF-kappaB signaling 3.7411027891823e-07 194 128 12 0.09375 0.0618556701030928
GO:BP GO:0002683 negative regulation of immune system process 4.53504666281629e-07 420 119 16 0.134453781512605 0.0380952380952381
GO:BP GO:0002699 positive regulation of immune effector process 5.04350581123048e-07 215 119 12 0.100840336134454 0.0558139534883721
GO:BP GO:0002711 positive regulation of T cell mediated immunity 5.12955152611314e-07 48 65 6 0.0923076923076923 0.125
GO:BP GO:1903901 negative regulation of viral life cycle 5.2601281615471e-07 26 59 5 0.0847457627118644 0.192307692307692
GO:BP GO:0001911 negative regulation of leukocyte mediated cytotoxicity 5.2601281615471e-07 20 78 5 0.0641025641025641 0.25
GO:BP GO:0048583 regulation of response to stimulus 5.34627521072182e-07 4278 131 60 0.458015267175573 0.0140252454417952
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 6.42705731566643e-07 177 119 11 0.092436974789916 0.0621468926553672
GO:BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 6.95182293231931e-07 251 128 13 0.1015625 0.051792828685259
GO:BP GO:0050852 T cell receptor signaling pathway 7.34931863549716e-07 203 131 12 0.0916030534351145 0.0591133004926108
GO:BP GO:0001916 positive regulation of T cell mediated cytotoxicity 8.20943551297695e-07 26 65 5 0.0769230769230769 0.192307692307692
GO:BP GO:0032020 ISG15-protein conjugation 8.5323420563222e-07 6 126 4 0.0317460317460317 0.666666666666667
GO:BP GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib 1.12552322306782e-06 3 65 3 0.0461538461538462 1
GO:BP GO:0002718 regulation of cytokine production involved in immune response 1.24885813429511e-06 85 73 7 0.0958904109589041 0.0823529411764706
GO:BP GO:0031342 negative regulation of cell killing 1.29745977786783e-06 24 78 5 0.0641025641025641 0.208333333333333
GO:BP GO:0002720 positive regulation of cytokine production involved in immune response 1.5034517676187e-06 54 119 7 0.0588235294117647 0.12962962962963
GO:BP GO:0060700 regulation of ribonuclease activity 1.6548714444576e-06 9 89 4 0.0449438202247191 0.444444444444444
GO:BP GO:0002704 negative regulation of leukocyte mediated immunity 1.95279964650349e-06 51 78 6 0.0769230769230769 0.117647058823529
GO:BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 1.95279964650349e-06 185 128 11 0.0859375 0.0594594594594595
GO:BP GO:0050688 regulation of defense response to virus 2.30760924141134e-06 71 145 8 0.0551724137931034 0.112676056338028
GO:BP GO:0002367 cytokine production involved in immune response 2.36060213829615e-06 94 73 7 0.0958904109589041 0.074468085106383
GO:BP GO:0002475 antigen processing and presentation via MHC class Ib 2.47616858392459e-06 13 65 4 0.0615384615384615 0.307692307692308
GO:BP GO:0070555 response to interleukin-1 2.62170040465866e-06 215 114 11 0.0964912280701754 0.0511627906976744
GO:BP GO:0032607 interferon-alpha production 2.79002659107968e-06 30 73 5 0.0684931506849315 0.166666666666667
GO:BP GO:0032647 regulation of interferon-alpha production 2.79002659107968e-06 30 73 5 0.0684931506849315 0.166666666666667
GO:BP GO:0060759 regulation of response to cytokine stimulus 2.81133611904503e-06 197 99 10 0.101010101010101 0.050761421319797
GO:BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 3.32377574759967e-06 291 128 13 0.1015625 0.0446735395189003
GO:BP GO:0001914 regulation of T cell mediated cytotoxicity 3.39211355677038e-06 35 65 5 0.0769230769230769 0.142857142857143
GO:BP GO:0002456 T cell mediated immunity 3.89535300034898e-06 98 76 7 0.0921052631578947 0.0714285714285714
GO:BP GO:0002703 regulation of leukocyte mediated immunity 5.20701076655235e-06 205 78 9 0.115384615384615 0.0439024390243902
GO:BP GO:0039530 MDA-5 signaling pathway 5.3176522993001e-06 10 108 4 0.037037037037037 0.4
GO:BP GO:0031348 negative regulation of defense response 5.4143459950436e-06 246 108 11 0.101851851851852 0.0447154471544715
GO:BP GO:0002709 regulation of T cell mediated immunity 5.5302910876204e-06 74 65 6 0.0923076923076923 0.0810810810810811
GO:BP GO:0071347 cellular response to interleukin-1 5.58741468104186e-06 185 114 10 0.087719298245614 0.0540540540540541
GO:BP GO:0002702 positive regulation of production of molecular mediator of immune response 6.48759951041852e-06 100 119 8 0.0672268907563025 0.08
GO:BP GO:1902036 regulation of hematopoietic stem cell differentiation 6.97530619045625e-06 75 109 7 0.0642201834862385 0.0933333333333333
GO:BP GO:0140289 protein mono-ADP-ribosylation 7.37184896498954e-06 12 96 4 0.0416666666666667 0.333333333333333
GO:BP GO:0010629 negative regulation of gene expression 7.82421052869819e-06 1460 109 26 0.238532110091743 0.0178082191780822
GO:BP GO:0001913 T cell mediated cytotoxicity 7.98645767311866e-06 42 65 5 0.0769230769230769 0.119047619047619
GO:BP GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib 8.90712137903399e-06 5 65 3 0.0461538461538462 0.6
GO:BP GO:0002700 regulation of production of molecular mediator of immune response 1.15328677175847e-05 148 119 9 0.0756302521008403 0.0608108108108108
GO:BP GO:0051701 biological process involved in interaction with host 1.15566005192393e-05 221 41 7 0.170731707317073 0.0316742081447964
GO:BP GO:0002705 positive regulation of leukocyte mediated immunity 1.18246004615928e-05 122 73 7 0.0958904109589041 0.0573770491803279
GO:BP GO:0060760 positive regulation of response to cytokine stimulus 1.30475851321494e-05 57 99 6 0.0606060606060606 0.105263157894737
GO:BP GO:0002221 pattern recognition receptor signaling pathway 1.39935357334557e-05 213 138 11 0.0797101449275362 0.0516431924882629
GO:BP GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane 1.40107591863595e-05 6 61 3 0.0491803278688525 0.5
GO:BP GO:0001910 regulation of leukocyte mediated cytotoxicity 1.48312192712298e-05 74 78 6 0.0769230769230769 0.0810810810810811
GO:BP GO:0002698 negative regulation of immune effector process 1.55201440872131e-05 125 108 8 0.0740740740740741 0.064
GO:BP GO:0042269 regulation of natural killer cell mediated cytotoxicity 1.62804525834732e-05 41 78 5 0.0641025641025641 0.121951219512195
GO:BP GO:0016567 protein ubiquitination 1.62804525834732e-05 892 126 21 0.166666666666667 0.023542600896861
GO:BP GO:0042270 protection from natural killer cell mediated cytotoxicity 1.64017143878194e-05 6 65 3 0.0461538461538462 0.5
GO:BP GO:0032446 protein modification by small protein conjugation 1.66755771550239e-05 973 126 22 0.174603174603175 0.0226104830421377
GO:BP GO:0001912 positive regulation of leukocyte mediated cytotoxicity 1.94357359598608e-05 51 65 5 0.0769230769230769 0.0980392156862745
GO:BP GO:1901532 regulation of hematopoietic progenitor cell differentiation 1.96790394427273e-05 89 109 7 0.0642201834862385 0.0786516853932584
GO:BP GO:0060218 hematopoietic stem cell differentiation 1.96790394427273e-05 89 109 7 0.0642201834862385 0.0786516853932584
GO:BP GO:0002707 negative regulation of lymphocyte mediated immunity 1.97963035208332e-05 43 78 5 0.0641025641025641 0.116279069767442
GO:BP GO:0046596 regulation of viral entry into host cell 1.97963035208332e-05 43 78 5 0.0641025641025641 0.116279069767442
GO:BP GO:0052548 regulation of endopeptidase activity 2.08879108803114e-05 437 103 13 0.12621359223301 0.0297482837528604
GO:BP GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.15442565226206e-05 96 65 6 0.0923076923076923 0.0625
GO:BP GO:0034343 type III interferon production 2.16713338359276e-05 6 73 3 0.0410958904109589 0.5
GO:BP GO:0034344 regulation of type III interferon production 2.16713338359276e-05 6 73 3 0.0410958904109589 0.5
GO:BP GO:0006471 protein ADP-ribosylation 2.16713338359276e-05 36 96 5 0.0520833333333333 0.138888888888889
GO:BP GO:0002715 regulation of natural killer cell mediated immunity 2.39917926976062e-05 45 78 5 0.0641025641025641 0.111111111111111
GO:BP GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 2.44898365545616e-05 33 108 5 0.0462962962962963 0.151515151515152
GO:BP GO:0002819 regulation of adaptive immune response 2.68708591628487e-05 167 119 9 0.0756302521008403 0.0538922155688623
GO:BP GO:0002821 positive regulation of adaptive immune response 2.77572798887234e-05 101 65 6 0.0923076923076923 0.0594059405940594
GO:BP GO:0070647 protein modification by small protein conjugation or removal 3.03839427352248e-05 1184 109 22 0.201834862385321 0.0185810810810811
GO:BP GO:0002708 positive regulation of lymphocyte mediated immunity 3.25444378662609e-05 104 65 6 0.0923076923076923 0.0576923076923077
GO:BP GO:0031343 positive regulation of cell killing 3.64909013103834e-05 59 65 5 0.0769230769230769 0.0847457627118644
GO:BP GO:0002724 regulation of T cell cytokine production 3.83472028793695e-05 33 52 4 0.0769230769230769 0.121212121212121
GO:BP GO:0006521 regulation of cellular amino acid metabolic process 3.83472028793695e-05 64 109 6 0.055045871559633 0.09375
GO:BP GO:0052372 modulation by symbiont of entry into host 3.84340898068188e-05 50 78 5 0.0641025641025641 0.1
GO:BP GO:0002250 adaptive immune response 3.84340898068188e-05 689 131 18 0.137404580152672 0.0261248185776488
GO:BP GO:0052547 regulation of peptidase activity 3.91097264890897e-05 467 103 13 0.12621359223301 0.0278372591006424
GO:BP GO:0032727 positive regulation of interferon-alpha production 3.91097264890897e-05 24 73 4 0.0547945205479452 0.166666666666667
GO:BP GO:0001818 negative regulation of cytokine production 4.09306563599904e-05 381 126 13 0.103174603174603 0.0341207349081365
GO:BP GO:0031341 regulation of cell killing 4.70466579882658e-05 93 78 6 0.0769230769230769 0.0645161290322581
GO:BP GO:0010468 regulation of gene expression 5.1114009573438e-05 5196 138 65 0.471014492753623 0.012509622786759
GO:BP GO:0002369 T cell cytokine production 5.20615084535088e-05 36 52 4 0.0769230769230769 0.111111111111111
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 5.7014996670198e-05 3241 138 47 0.340579710144928 0.0145016970070966
GO:BP GO:0032069 regulation of nuclease activity 5.76473213910294e-05 22 89 4 0.0449438202247191 0.181818181818182
GO:BP GO:0002706 regulation of lymphocyte mediated immunity 6.03022298010653e-05 151 78 7 0.0897435897435897 0.0463576158940397
GO:BP GO:0050851 antigen receptor-mediated signaling pathway 6.14381913017303e-05 323 131 12 0.0916030534351145 0.0371517027863777
GO:BP GO:0046718 viral entry into host cell 6.36864026308995e-05 141 119 8 0.0672268907563025 0.0567375886524823
GO:BP GO:0002440 production of molecular mediator of immune response 6.60521304972714e-05 189 119 9 0.0756302521008403 0.0476190476190476
GO:BP GO:0009967 positive regulation of signal transduction 7.68356724033848e-05 1598 114 26 0.228070175438596 0.016270337922403
GO:BP GO:0051336 regulation of hydrolase activity 7.68356724033848e-05 1321 48 14 0.291666666666667 0.0105980317940954
GO:BP GO:0048585 negative regulation of response to stimulus 8.04135606877191e-05 1733 38 14 0.368421052631579 0.00807847663012118
GO:BP GO:0030097 hemopoiesis 8.37998327237972e-05 928 58 13 0.224137931034483 0.0140086206896552
GO:BP GO:2000736 regulation of stem cell differentiation 8.63771398263575e-05 115 41 5 0.121951219512195 0.0434782608695652
GO:BP GO:0010628 positive regulation of gene expression 8.63771398263575e-05 1160 119 22 0.184873949579832 0.0189655172413793
GO:BP GO:0048523 negative regulation of cellular process 8.72282300914934e-05 5139 42 26 0.619047619047619 0.00505935006810664
GO:BP GO:0002230 positive regulation of defense response to virus by host 8.79909635834263e-05 33 145 5 0.0344827586206897 0.151515151515152
GO:BP GO:0002443 leukocyte mediated immunity 9.41666018500011e-05 877 101 17 0.168316831683168 0.0193842645381984
GO:BP GO:0001909 leukocyte mediated cytotoxicity 9.61152904994617e-05 107 78 6 0.0769230769230769 0.0560747663551402
GO:BP GO:0002520 immune system development 9.82356466788199e-05 1020 116 20 0.172413793103448 0.0196078431372549
GO:BP GO:0042267 natural killer cell mediated cytotoxicity 9.84328918162425e-05 62 78 5 0.0641025641025641 0.0806451612903226
GO:BP GO:0046597 negative regulation of viral entry into host cell 0.000103881204640071 20 35 3 0.0857142857142857 0.15
GO:BP GO:0035457 cellular response to interferon-alpha 0.000104020396556111 13 55 3 0.0545454545454545 0.230769230769231
GO:BP GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 0.000104181049725936 78 109 6 0.055045871559633 0.0769230769230769
GO:BP GO:0001959 regulation of cytokine-mediated signaling pathway 0.000105162676686954 184 99 8 0.0808080808080808 0.0434782608695652
GO:BP GO:0044409 entry into host 0.000110908909450697 154 119 8 0.0672268907563025 0.051948051948052
GO:BP GO:0032481 positive regulation of type I interferon production 0.0001126993125321 80 108 6 0.0555555555555556 0.075
GO:BP GO:1901224 positive regulation of NIK/NF-kappaB signaling 0.000115657604348363 68 128 6 0.046875 0.0882352941176471
GO:BP GO:0002228 natural killer cell mediated immunity 0.00011873238179842 65 78 5 0.0641025641025641 0.0769230769230769
GO:BP GO:0048534 hematopoietic or lymphoid organ development 0.00011873238179842 966 58 13 0.224137931034483 0.0134575569358178
GO:BP GO:0046719 regulation by virus of viral protein levels in host cell 0.000124330151285241 8 101 3 0.0297029702970297 0.375
GO:BP GO:0002449 lymphocyte mediated immunity 0.000125802340310297 354 130 12 0.0923076923076923 0.0338983050847458
GO:BP GO:0002244 hematopoietic progenitor cell differentiation 0.000125812006234427 172 109 8 0.073394495412844 0.0465116279069767
GO:BP GO:0033238 regulation of cellular amine metabolic process 0.000132395268999863 82 109 6 0.055045871559633 0.0731707317073171
GO:BP GO:0010499 proteasomal ubiquitin-independent protein catabolic process 0.000132746614232741 23 109 4 0.036697247706422 0.173913043478261
GO:BP GO:0001906 cell killing 0.000135651533680908 175 78 7 0.0897435897435897 0.04
GO:BP GO:0035567 non-canonical Wnt signaling pathway 0.000150652781166359 151 36 5 0.138888888888889 0.033112582781457
GO:BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.00015706691908278 363 130 12 0.0923076923076923 0.0330578512396694
GO:BP GO:0031145 anaphase-promoting complex-dependent catabolic process 0.000159030087560458 85 109 6 0.055045871559633 0.0705882352941176
GO:BP GO:0032648 regulation of interferon-beta production 0.000183831084174347 52 108 5 0.0462962962962963 0.0961538461538462
GO:BP GO:0002253 activation of immune response 0.000198359726460399 568 131 15 0.114503816793893 0.0264084507042254
GO:BP GO:0002429 immune response-activating cell surface receptor signaling pathway 0.000202786830021203 477 32 7 0.21875 0.0146750524109015
GO:BP GO:0002757 immune response-activating signal transduction 0.000202786830021203 477 32 7 0.21875 0.0146750524109015
GO:BP GO:0035458 cellular response to interferon-beta 0.000214335938185903 21 137 4 0.0291970802919708 0.19047619047619
GO:BP GO:0032608 interferon-beta production 0.000216384980076892 54 108 5 0.0462962962962963 0.0925925925925926
GO:BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.000217386201695477 152 65 6 0.0923076923076923 0.0394736842105263
GO:BP GO:0065009 regulation of molecular function 0.000222152020845817 3221 106 37 0.349056603773585 0.0114871158025458
GO:BP GO:0002507 tolerance induction 0.000250530755103385 29 102 4 0.0392156862745098 0.137931034482759
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 0.000254783898640339 512 131 14 0.106870229007634 0.02734375
GO:BP GO:0052126 movement in host environment 0.000270501224784425 177 119 8 0.0672268907563025 0.0451977401129944
GO:BP GO:0002764 immune response-regulating signaling pathway 0.000270501224784425 515 131 14 0.106870229007634 0.0271844660194175
GO:BP GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0.00027779449762857 95 32 4 0.125 0.0421052631578947
GO:BP GO:0050691 regulation of defense response to virus by host 0.000280132900931197 43 145 5 0.0344827586206897 0.116279069767442
GO:BP GO:0002726 positive regulation of T cell cytokine production 0.000296634950080839 20 52 3 0.0576923076923077 0.15
GO:BP GO:0006508 proteolysis 0.000305840720093027 1836 109 26 0.238532110091743 0.014161220043573
GO:BP GO:0009892 negative regulation of metabolic process 0.000305840720093027 3479 138 47 0.340579710144928 0.0135096292037942
GO:BP GO:0002218 activation of innate immune response 0.000312705277321441 144 109 7 0.0642201834862385 0.0486111111111111
GO:BP GO:0060255 regulation of macromolecule metabolic process 0.00032126141816857 6603 138 74 0.536231884057971 0.0112070271088899
GO:BP GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 0.000355921041993871 102 32 4 0.125 0.0392156862745098
GO:BP GO:0061025 membrane fusion 0.000355921041993871 179 61 6 0.0983606557377049 0.0335195530726257
GO:BP GO:0032102 negative regulation of response to external stimulus 0.00035715572132264 406 108 11 0.101851851851852 0.0270935960591133
GO:BP GO:0050830 defense response to Gram-positive bacterium 0.000383798661190802 101 66 5 0.0757575757575758 0.0495049504950495
GO:BP GO:0010647 positive regulation of cell communication 0.000383798661190802 1777 114 26 0.228070175438596 0.0146314012380416
GO:BP GO:0070498 interleukin-1-mediated signaling pathway 0.000387344601358471 105 32 4 0.125 0.0380952380952381
GO:BP GO:0023056 positive regulation of signaling 0.000399310438399941 1782 114 26 0.228070175438596 0.0145903479236813
GO:BP GO:0002237 response to molecule of bacterial origin 0.000403656832573282 361 123 11 0.0894308943089431 0.0304709141274238
GO:BP GO:0006954 inflammatory response 0.000418163351324624 794 114 16 0.140350877192982 0.0201511335012594
GO:BP GO:0019941 modification-dependent protein catabolic process 0.000419111243630745 662 36 8 0.222222222222222 0.0120845921450151
GO:BP GO:0060330 regulation of response to interferon-gamma 0.000427080737478097 26 46 3 0.0652173913043478 0.115384615384615
GO:BP GO:0060334 regulation of interferon-gamma-mediated signaling pathway 0.000427080737478097 26 46 3 0.0652173913043478 0.115384615384615
GO:BP GO:0060071 Wnt signaling pathway, planar cell polarity pathway 0.000451416867200199 110 32 4 0.125 0.0363636363636364
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 0.00046338818162843 673 36 8 0.222222222222222 0.011887072808321
GO:BP GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 0.000463864055913636 111 32 4 0.125 0.036036036036036
GO:BP GO:0002223 stimulatory C-type lectin receptor signaling pathway 0.000478480681793491 112 32 4 0.125 0.0357142857142857
GO:BP GO:1902750 negative regulation of cell cycle G2/M phase transition 0.00049340446219207 113 32 4 0.125 0.0353982300884956
GO:BP GO:0090175 regulation of establishment of planar polarity 0.000508638462223415 114 32 4 0.125 0.0350877192982456
GO:BP GO:0002220 innate immune response activating cell surface receptor signaling pathway 0.000524185735685506 115 32 4 0.125 0.0347826086956522
GO:BP GO:0002758 innate immune response-activating signal transduction 0.000540049324942228 116 32 4 0.125 0.0344827586206897
GO:BP GO:0043620 regulation of DNA-templated transcription in response to stress 0.000556232260809637 117 32 4 0.125 0.0341880341880342
GO:BP GO:0051603 proteolysis involved in cellular protein catabolic process 0.0006061086051769 750 138 17 0.123188405797101 0.0226666666666667
GO:BP GO:0044106 cellular amine metabolic process 0.000612869014120325 163 109 7 0.0642201834862385 0.0429447852760736
GO:BP GO:0071360 cellular response to exogenous dsRNA 0.000612869014120325 19 73 3 0.0410958904109589 0.157894736842105
GO:BP GO:0032728 positive regulation of interferon-beta production 0.000638520219763992 36 108 4 0.037037037037037 0.111111111111111
GO:BP GO:0023051 regulation of signaling 0.000640896360631002 3578 46 21 0.456521739130435 0.00586920067076579
GO:BP GO:0046700 heterocycle catabolic process 0.000693640094905057 602 109 13 0.119266055045872 0.0215946843853821
GO:BP GO:0030178 negative regulation of Wnt signaling pathway 0.000696516701521227 218 36 5 0.138888888888889 0.0229357798165138
GO:BP GO:0016579 protein deubiquitination 0.000700267262334837 292 109 9 0.0825688073394495 0.0308219178082192
GO:BP GO:0009308 amine metabolic process 0.000722874423665443 168 109 7 0.0642201834862385 0.0416666666666667
GO:BP GO:0009966 regulation of signal transduction 0.000743209682780326 3165 114 37 0.324561403508772 0.0116903633491311
GO:BP GO:0044270 cellular nitrogen compound catabolic process 0.000752154268395749 608 109 13 0.119266055045872 0.0213815789473684
GO:BP GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 0.000757994126196939 73 108 5 0.0462962962962963 0.0684931506849315
GO:BP GO:0010950 positive regulation of endopeptidase activity 0.000757994126196939 187 99 7 0.0707070707070707 0.0374331550802139
GO:BP GO:0009968 negative regulation of signal transduction 0.000767734852508018 1364 38 11 0.289473684210526 0.00806451612903226
GO:BP GO:0007164 establishment of tissue polarity 0.000779184424342342 130 32 4 0.125 0.0307692307692308
GO:BP GO:0001736 establishment of planar polarity 0.000779184424342342 130 32 4 0.125 0.0307692307692308
GO:BP GO:0046640 regulation of alpha-beta T cell proliferation 0.00078892169375314 35 119 4 0.0336134453781513 0.114285714285714
GO:BP GO:0045646 regulation of erythrocyte differentiation 0.000839379058586439 47 33 3 0.0909090909090909 0.0638297872340425
GO:BP GO:0030162 regulation of proteolysis 0.000885018353634015 752 103 14 0.135922330097087 0.0186170212765957
GO:BP GO:0019439 aromatic compound catabolic process 0.000925672760980724 623 109 13 0.119266055045872 0.0208667736757624
GO:BP GO:0046641 positive regulation of alpha-beta T cell proliferation 0.000937934095994572 21 78 3 0.0384615384615385 0.142857142857143
GO:BP GO:0051239 regulation of multicellular organismal process 0.000947611253615936 2861 78 26 0.333333333333333 0.00908773156239077
GO:BP GO:0032496 response to lipopolysaccharide 0.00100294539077397 338 123 10 0.0813008130081301 0.029585798816568
GO:BP GO:0071359 cellular response to dsRNA 0.00100800599497503 23 73 3 0.0410958904109589 0.130434782608696
GO:BP GO:0070646 protein modification by small protein removal 0.00102216878043386 310 109 9 0.0825688073394495 0.0290322580645161
GO:BP GO:0046633 alpha-beta T cell proliferation 0.0010486408344674 38 119 4 0.0336134453781513 0.105263157894737
GO:BP GO:0062208 positive regulation of pattern recognition receptor signaling pathway 0.00117149750542787 43 108 4 0.037037037037037 0.0930232558139535
GO:BP GO:0010952 positive regulation of peptidase activity 0.00125001554957812 205 99 7 0.0707070707070707 0.0341463414634146
GO:BP GO:0051100 negative regulation of binding 0.00126168318026115 163 55 5 0.0909090909090909 0.0306748466257669
GO:BP GO:0010646 regulation of cell communication 0.00129266595853839 3543 42 19 0.452380952380952 0.00536268698842789
GO:BP GO:0090263 positive regulation of canonical Wnt signaling pathway 0.00129893596025349 151 32 4 0.125 0.0264900662251656
GO:BP GO:0001738 morphogenesis of a polarized epithelium 0.00132776793119114 152 32 4 0.125 0.0263157894736842
GO:BP GO:0016050 vesicle organization 0.00133099754053509 341 61 7 0.114754098360656 0.0205278592375367
GO:BP GO:1901361 organic cyclic compound catabolic process 0.0013441591400757 651 109 13 0.119266055045872 0.0199692780337942
GO:BP GO:0010648 negative regulation of cell communication 0.00135860571731254 1468 38 11 0.289473684210526 0.00749318801089918
GO:BP GO:0023057 negative regulation of signaling 0.00137865125992933 1471 38 11 0.289473684210526 0.00747790618626785
GO:BP GO:1901222 regulation of NIK/NF-kappaB signaling 0.00137865125992933 113 128 6 0.046875 0.0530973451327434
GO:BP GO:0044257 cellular protein catabolic process 0.00138215636882764 813 138 17 0.123188405797101 0.020910209102091
GO:BP GO:0044265 cellular macromolecule catabolic process 0.00139029881624793 1231 138 22 0.159420289855072 0.0178716490658002
GO:BP GO:0034655 nucleobase-containing compound catabolic process 0.00140943556393907 567 109 12 0.110091743119266 0.0211640211640212
GO:BP GO:0001961 positive regulation of cytokine-mediated signaling pathway 0.00143809779631058 50 99 4 0.0404040404040404 0.08
GO:BP GO:0051241 negative regulation of multicellular organismal process 0.0014700646865811 1160 108 18 0.166666666666667 0.0155172413793103
GO:BP GO:0051098 regulation of binding 0.00158065158485032 365 59 7 0.11864406779661 0.0191780821917808
GO:BP GO:0048518 positive regulation of biological process 0.00169823862362291 6363 114 59 0.517543859649123 0.00927235580700927
GO:BP GO:0038095 Fc-epsilon receptor signaling pathway 0.00181764845129573 167 32 4 0.125 0.0239520958083832
GO:BP GO:0010467 gene expression 0.00184723575455792 6179 82 44 0.536585365853659 0.00712089334843826
GO:BP GO:0002275 myeloid cell activation involved in immune response 0.00203906326933448 547 101 11 0.108910891089109 0.020109689213894
GO:BP GO:0002224 toll-like receptor signaling pathway 0.00203906326933448 161 138 7 0.0507246376811594 0.0434782608695652
GO:BP GO:0045595 regulation of cell differentiation 0.00204981622971609 1679 41 12 0.292682926829268 0.00714711137581894
GO:BP GO:0006401 RNA catabolic process 0.00206434693221552 424 109 10 0.0917431192660551 0.0235849056603774
GO:BP GO:0032731 positive regulation of interleukin-1 beta production 0.00212241706756289 56 99 4 0.0404040404040404 0.0714285714285714
GO:BP GO:0002444 myeloid leukocyte mediated immunity 0.00213249317879902 551 101 11 0.108910891089109 0.0199637023593466
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 0.00222510233446211 655 36 7 0.194444444444444 0.0106870229007634
GO:BP GO:0019222 regulation of metabolic process 0.00227082099243431 7148 138 75 0.543478260869565 0.0104924454392837
GO:BP GO:0071222 cellular response to lipopolysaccharide 0.00230364710317494 200 114 7 0.0614035087719298 0.035
GO:BP GO:0048863 stem cell differentiation 0.00233397139006116 258 41 5 0.121951219512195 0.0193798449612403
GO:BP GO:2000027 regulation of animal organ morphogenesis 0.00247601882611509 184 32 4 0.125 0.0217391304347826
GO:BP GO:0030177 positive regulation of Wnt signaling pathway 0.00247601882611509 184 32 4 0.125 0.0217391304347826
GO:BP GO:0006520 cellular amino acid metabolic process 0.00253242448815698 341 32 5 0.15625 0.0146627565982405
GO:BP GO:0090090 negative regulation of canonical Wnt signaling pathway 0.00261680672505083 187 32 4 0.125 0.0213903743315508
GO:BP GO:0002274 myeloid leukocyte activation 0.00277265549760017 667 101 12 0.118811881188119 0.0179910044977511
GO:BP GO:0043488 regulation of mRNA stability 0.00281275646458642 191 32 4 0.125 0.0209424083769634
GO:BP GO:0035556 intracellular signal transduction 0.00281275646458642 2772 114 32 0.280701754385965 0.0115440115440115
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 0.00284341910067448 240 99 7 0.0707070707070707 0.0291666666666667
GO:BP GO:0010565 regulation of cellular ketone metabolic process 0.00291825279793317 194 32 4 0.125 0.0206185567010309
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 0.00298907365320672 2518 4 4 1 0.00158856235107228
GO:BP GO:0060338 regulation of type I interferon-mediated signaling pathway 0.00311921311094436 35 74 3 0.0405405405405405 0.0857142857142857
GO:BP GO:0045321 leukocyte activation 0.00324716557070891 1332 119 20 0.168067226890756 0.015015015015015
GO:BP GO:0071219 cellular response to molecule of bacterial origin 0.00327118022555309 214 114 7 0.0614035087719298 0.0327102803738318
GO:BP GO:0043487 regulation of RNA stability 0.00328809858311511 201 32 4 0.125 0.0199004975124378
GO:BP GO:0030163 protein catabolic process 0.00329465594851422 974 126 17 0.134920634920635 0.0174537987679671
GO:BP GO:1901565 organonitrogen compound catabolic process 0.00338593379640904 1358 126 21 0.166666666666667 0.0154639175257732
GO:BP GO:0032732 positive regulation of interleukin-1 production 0.00345120244669474 65 99 4 0.0404040404040404 0.0615384615384615
GO:BP GO:0010389 regulation of G2/M transition of mitotic cell cycle 0.0035384430778868 207 32 4 0.125 0.0193236714975845
GO:BP GO:0062207 regulation of pattern recognition receptor signaling pathway 0.00356741168373961 108 108 5 0.0462962962962963 0.0462962962962963
GO:BP GO:0050793 regulation of developmental process 0.00356741168373961 2605 42 15 0.357142857142857 0.00575815738963532
GO:BP GO:0006906 vesicle fusion 0.00363459697550051 108 61 4 0.0655737704918033 0.037037037037037
GO:BP GO:0039529 RIG-I signaling pathway 0.00366072748951789 26 108 3 0.0277777777777778 0.115384615384615
GO:BP GO:0043170 macromolecule metabolic process 0.00376658576978802 9796 83 60 0.72289156626506 0.00612494895875868
GO:BP GO:0031324 negative regulation of cellular metabolic process 0.00378533603130747 2719 4 4 1 0.00147112909157779
GO:BP GO:0071456 cellular response to hypoxia 0.00378533603130747 212 32 4 0.125 0.0188679245283019
GO:BP GO:0042832 defense response to protozoan 0.00378533603130747 25 114 3 0.0263157894736842 0.12
GO:BP GO:0061013 regulation of mRNA catabolic process 0.00384231681350508 213 32 4 0.125 0.0187793427230047
GO:BP GO:0030218 erythrocyte differentiation 0.00385109424419964 116 58 4 0.0689655172413793 0.0344827586206897
GO:BP GO:0000266 mitochondrial fission 0.00392546455506302 41 70 3 0.0428571428571429 0.0731707317073171
GO:BP GO:0032655 regulation of interleukin-12 production 0.00407095527904752 60 114 4 0.0350877192982456 0.0666666666666667
GO:BP GO:0032615 interleukin-12 production 0.00407095527904752 60 114 4 0.0350877192982456 0.0666666666666667
GO:BP GO:0032760 positive regulation of tumor necrosis factor production 0.00412878176664097 88 78 4 0.0512820512820513 0.0454545454545455
GO:BP GO:0009435 NAD biosynthetic process 0.00414465428803263 29 102 3 0.0294117647058824 0.103448275862069
GO:BP GO:0050790 regulation of catalytic activity 0.00414465428803263 2545 48 16 0.333333333333333 0.00628683693516699
GO:BP GO:0001562 response to protozoan 0.00414465428803263 26 114 3 0.0263157894736842 0.115384615384615
GO:BP GO:0002366 leukocyte activation involved in immune response 0.0041595911825008 717 114 13 0.114035087719298 0.0181311018131102
GO:BP GO:0090174 organelle membrane fusion 0.00425386024954961 114 61 4 0.0655737704918033 0.0350877192982456
GO:BP GO:0036294 cellular response to decreased oxygen levels 0.00432106059477043 222 32 4 0.125 0.018018018018018
GO:BP GO:0007259 receptor signaling pathway via JAK-STAT 0.00432106059477043 174 71 5 0.0704225352112676 0.028735632183908
GO:BP GO:0070661 leukocyte proliferation 0.00432106059477043 325 131 9 0.0687022900763359 0.0276923076923077
GO:BP GO:0002263 cell activation involved in immune response 0.00432285484713961 721 114 13 0.114035087719298 0.0180305131761442
GO:BP GO:1902749 regulation of cell cycle G2/M phase transition 0.00437117692774121 223 32 4 0.125 0.0179372197309417
GO:BP GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 0.00453751485282676 91 78 4 0.0512820512820513 0.043956043956044
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.00456153013773507 3483 80 28 0.35 0.00803904679873672
GO:BP GO:0050794 regulation of cellular process 0.00460350562197284 11473 48 41 0.854166666666667 0.00357360760045324
GO:BP GO:0044248 cellular catabolic process 0.00463588938770565 2347 138 32 0.231884057971014 0.0136344269279932
GO:BP GO:0034101 erythrocyte homeostasis 0.00465427524972073 124 58 4 0.0689655172413793 0.032258064516129
GO:BP GO:0051091 positive regulation of DNA-binding transcription factor activity 0.00467907455197172 270 128 8 0.0625 0.0296296296296296
GO:BP GO:0046135 pyrimidine nucleoside catabolic process 0.00479163373196684 22 145 3 0.0206896551724138 0.136363636363636
GO:BP GO:0001775 cell activation 0.00479163373196684 1495 119 21 0.176470588235294 0.0140468227424749
GO:BP GO:0009057 macromolecule catabolic process 0.00482742348543665 1468 138 23 0.166666666666667 0.0156675749318801
GO:BP GO:0042098 T cell proliferation 0.00499869245951509 205 131 7 0.0534351145038168 0.0341463414634146
GO:BP GO:0008219 cell death 0.00513463891675726 2292 102 25 0.245098039215686 0.0109075043630017
GO:BP GO:0019363 pyridine nucleotide biosynthetic process 0.00516720198016056 32 102 3 0.0294117647058824 0.09375
GO:BP GO:0019359 nicotinamide nucleotide biosynthetic process 0.00516720198016056 32 102 3 0.0294117647058824 0.09375
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.00517960707593463 1037 114 16 0.140350877192982 0.0154291224686596
GO:BP GO:0071216 cellular response to biotic stimulus 0.00517960707593463 238 114 7 0.0614035087719298 0.0294117647058824
GO:BP GO:0097696 receptor signaling pathway via STAT 0.00518038686242406 184 71 5 0.0704225352112676 0.0271739130434783
GO:BP GO:0038093 Fc receptor signaling pathway 0.00521610218276938 238 32 4 0.125 0.0168067226890756
GO:BP GO:0071453 cellular response to oxygen levels 0.00534162793881573 240 32 4 0.125 0.0166666666666667
GO:BP GO:0043299 leukocyte degranulation 0.00534162793881573 535 101 10 0.099009900990099 0.0186915887850467
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.0053613173291898 1082 4 3 0.75 0.00277264325323475
GO:BP GO:0030111 regulation of Wnt signaling pathway 0.00548311913033374 376 36 5 0.138888888888889 0.0132978723404255
GO:BP GO:0019985 translesion synthesis 0.00592123025940656 42 82 3 0.0365853658536585 0.0714285714285714
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 0.00595190420477401 434 32 5 0.15625 0.0115207373271889
GO:BP GO:0050789 regulation of biological process 0.00610876038156973 12091 48 42 0.875 0.00347365809279629
GO:BP GO:0051248 negative regulation of protein metabolic process 0.00634185205089417 1151 4 3 0.75 0.00260642919200695
GO:BP GO:0072525 pyridine-containing compound biosynthetic process 0.00641167481884113 35 102 3 0.0294117647058824 0.0857142857142857
GO:BP GO:0046496 nicotinamide nucleotide metabolic process 0.00641167481884113 35 102 3 0.0294117647058824 0.0857142857142857
GO:BP GO:0019362 pyridine nucleotide metabolic process 0.00641167481884113 35 102 3 0.0294117647058824 0.0857142857142857
GO:BP GO:0051092 positive regulation of NF-kappaB transcription factor activity 0.00662009794710127 162 128 6 0.046875 0.037037037037037
GO:BP GO:0043330 response to exogenous dsRNA 0.00688755709817003 50 73 3 0.0410958904109589 0.06
GO:BP GO:0009893 positive regulation of metabolic process 0.00696569472924995 3783 80 29 0.3625 0.00766587364525509
GO:BP GO:0000086 G2/M transition of mitotic cell cycle 0.00706630883973311 265 109 7 0.0642201834862385 0.0264150943396226
GO:BP GO:1901991 negative regulation of mitotic cell cycle phase transition 0.00710064586724879 262 32 4 0.125 0.0152671755725191
GO:BP GO:0007005 mitochondrion organization 0.0072732320810369 561 101 10 0.099009900990099 0.017825311942959
GO:BP GO:2001056 positive regulation of cysteine-type endopeptidase activity 0.007380515260209 154 138 6 0.0434782608695652 0.038961038961039
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.00761773619962009 1455 78 15 0.192307692307692 0.0103092783505155
GO:BP GO:0042180 cellular ketone metabolic process 0.00787246017963918 271 109 7 0.0642201834862385 0.025830258302583
GO:BP GO:0051346 negative regulation of hydrolase activity 0.00804836986351216 470 9 3 0.333333333333333 0.00638297872340425
GO:BP GO:0070663 regulation of leukocyte proliferation 0.00836216564677566 251 119 7 0.0588235294117647 0.0278884462151394
GO:BP GO:0046651 lymphocyte proliferation 0.00836216564677566 294 131 8 0.0610687022900763 0.0272108843537415
GO:BP GO:0002262 myeloid cell homeostasis 0.00854979807577778 151 58 4 0.0689655172413793 0.0264900662251656
GO:BP GO:0032943 mononuclear cell proliferation 0.00883888882830452 297 131 8 0.0610687022900763 0.0269360269360269
GO:BP GO:1901988 negative regulation of cell cycle phase transition 0.00885619441834466 281 32 4 0.125 0.0142348754448399
GO:BP GO:0044092 negative regulation of molecular function 0.00896472011071717 1219 94 15 0.159574468085106 0.0123051681706317
GO:BP GO:0032609 interferon-gamma production 0.00901726346496601 115 131 5 0.0381679389312977 0.0434782608695652
GO:BP GO:0043331 response to dsRNA 0.00901726346496601 56 73 3 0.0410958904109589 0.0535714285714286
GO:BP GO:0019730 antimicrobial humoral response 0.00901726346496601 145 104 5 0.0480769230769231 0.0344827586206897
GO:BP GO:0044839 cell cycle G2/M phase transition 0.00901726346496601 283 32 4 0.125 0.0141342756183746
GO:BP GO:0034121 regulation of toll-like receptor signaling pathway 0.00911083161191825 79 52 3 0.0576923076923077 0.0379746835443038
GO:BP GO:0071677 positive regulation of mononuclear cell migration 0.00915340729873304 65 138 4 0.0289855072463768 0.0615384615384615
GO:BP GO:0042742 defense response to bacterium 0.0092191099088906 349 88 7 0.0795454545454545 0.0200573065902579
GO:BP GO:0048284 organelle fusion 0.0092435347074186 148 61 4 0.0655737704918033 0.027027027027027
GO:BP GO:0010498 proteasomal protein catabolic process 0.00934411692280614 491 32 5 0.15625 0.010183299389002
GO:BP GO:0072524 pyridine-containing compound metabolic process 0.00935832670036413 41 102 3 0.0294117647058824 0.0731707317073171
GO:BP GO:0043112 receptor metabolic process 0.00938489310709697 174 88 5 0.0568181818181818 0.028735632183908
GO:BP GO:0002886 regulation of myeloid leukocyte mediated immunity 0.00956017682935074 54 78 3 0.0384615384615385 0.0555555555555556
GO:BP GO:0060828 regulation of canonical Wnt signaling pathway 0.0103492859399107 298 32 4 0.125 0.0134228187919463
GO:BP GO:0008285 negative regulation of cell population proliferation 0.0103492859399107 790 41 7 0.170731707317073 0.00886075949367089
GO:BP GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 0.0103492859399107 42 104 3 0.0288461538461538 0.0714285714285714
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.0110708383477569 1042 32 7 0.21875 0.00671785028790787
GO:BP GO:0043687 post-translational protein modification 0.011132908634021 362 113 8 0.0707964601769911 0.0220994475138122
GO:BP GO:0032735 positive regulation of interleukin-12 production 0.0122153654980724 41 114 3 0.0263157894736842 0.0731707317073171
GO:BP GO:0006900 vesicle budding from membrane 0.0123999605606476 107 44 3 0.0681818181818182 0.0280373831775701
GO:BP GO:0006402 mRNA catabolic process 0.012454955887865 384 109 8 0.073394495412844 0.0208333333333333
GO:BP GO:1903706 regulation of hemopoiesis 0.0127056147586981 424 40 5 0.125 0.0117924528301887
GO:BP GO:0009164 nucleoside catabolic process 0.0127056147586981 33 145 3 0.0206896551724138 0.0909090909090909
GO:BP GO:0032651 regulation of interleukin-1 beta production 0.0129531634366808 102 99 4 0.0404040404040404 0.0392156862745098
GO:BP GO:0046822 regulation of nucleocytoplasmic transport 0.0130416120714112 115 42 3 0.0714285714285714 0.0260869565217391
GO:BP GO:0030099 myeloid cell differentiation 0.0131191454901821 428 58 6 0.103448275862069 0.014018691588785
GO:BP GO:0048522 positive regulation of cellular process 0.0133799507715348 5757 114 51 0.447368421052632 0.0088587806149036
GO:BP GO:0070936 protein K48-linked ubiquitination 0.0134418857388361 61 80 3 0.0375 0.0491803278688525
GO:BP GO:0045637 regulation of myeloid cell differentiation 0.0141355719603941 263 40 4 0.1 0.0152091254752852
GO:BP GO:0045930 negative regulation of mitotic cell cycle 0.0143403248317158 333 32 4 0.125 0.012012012012012
GO:BP GO:0006213 pyrimidine nucleoside metabolic process 0.0144521691542638 35 145 3 0.0206896551724138 0.0857142857142857
GO:BP GO:0002009 morphogenesis of an epithelium 0.0147293182526097 560 32 5 0.15625 0.00892857142857143
GO:BP GO:0006915 apoptotic process 0.01474276692048 1990 114 23 0.201754385964912 0.0115577889447236
GO:BP GO:0032611 interleukin-1 beta production 0.0147741949971972 107 99 4 0.0404040404040404 0.0373831775700935
GO:BP GO:0070665 positive regulation of leukocyte proliferation 0.015631365618992 155 114 5 0.043859649122807 0.032258064516129
GO:BP GO:0046635 positive regulation of alpha-beta T cell activation 0.0157682056075072 67 78 3 0.0384615384615385 0.0447761194029851
GO:BP GO:0060070 canonical Wnt signaling pathway 0.0159014969423512 345 32 4 0.125 0.0115942028985507
GO:BP GO:0051246 regulation of protein metabolic process 0.0159672894756097 2704 106 27 0.254716981132075 0.00998520710059172
GO:BP GO:0032091 negative regulation of protein binding 0.0163563751827608 97 55 3 0.0545454545454545 0.0309278350515464
GO:BP GO:0009056 catabolic process 0.0167393335424573 2744 110 28 0.254545454545455 0.0102040816326531
GO:BP GO:0012501 programmed cell death 0.016956810553016 2143 114 24 0.210526315789474 0.0111992533831078
GO:BP GO:1903311 regulation of mRNA metabolic process 0.0170729720437363 356 32 4 0.125 0.0112359550561798
GO:BP GO:0072529 pyrimidine-containing compound catabolic process 0.017196620423579 38 145 3 0.0206896551724138 0.0789473684210526
GO:BP GO:0046631 alpha-beta T cell activation 0.0177242065868954 155 119 5 0.0420168067226891 0.032258064516129
GO:BP GO:0016055 Wnt signaling pathway 0.0180815152695185 529 36 5 0.138888888888889 0.00945179584120983
GO:BP GO:0198738 cell-cell signaling by wnt 0.0183413766699274 531 36 5 0.138888888888889 0.00941619585687382
GO:BP GO:0001666 response to hypoxia 0.0184144192575256 367 32 4 0.125 0.0108991825613079
GO:BP GO:0042127 regulation of cell population proliferation 0.0185135212882841 1774 138 24 0.173913043478261 0.0135287485907554
GO:BP GO:0016192 vesicle-mediated transport 0.0186768998627887 2180 101 22 0.217821782178218 0.0100917431192661
GO:BP GO:0010948 negative regulation of cell cycle process 0.0190701078197653 372 32 4 0.125 0.010752688172043
GO:BP GO:0010524 positive regulation of calcium ion transport into cytosol 0.0193169794698158 56 104 3 0.0288461538461538 0.0535714285714286
GO:BP GO:0032652 regulation of interleukin-1 production 0.0194607022539571 119 99 4 0.0404040404040404 0.0336134453781513
GO:BP GO:0050670 regulation of lymphocyte proliferation 0.0194867812065857 230 119 6 0.0504201680672269 0.0260869565217391
GO:BP GO:0006810 transport 0.0194867812065857 5224 104 43 0.413461538461538 0.0082312404287902
GO:BP GO:1901564 organonitrogen compound metabolic process 0.0196749347499378 6792 114 57 0.5 0.00839222614840989
GO:BP GO:0045055 regulated exocytosis 0.0198744551472369 785 101 11 0.108910891089109 0.0140127388535032
GO:BP GO:1901658 glycosyl compound catabolic process 0.0198744551472369 41 145 3 0.0206896551724138 0.0731707317073171
GO:BP GO:0032944 regulation of mononuclear cell proliferation 0.0198744551472369 232 119 6 0.0504201680672269 0.0258620689655172
GO:BP GO:0036293 response to decreased oxygen levels 0.0201415415492895 382 32 4 0.125 0.0104712041884817
GO:BP GO:0046634 regulation of alpha-beta T cell activation 0.0208347357407484 102 119 4 0.0336134453781513 0.0392156862745098
GO:BP GO:0072527 pyrimidine-containing compound metabolic process 0.0208933363395072 84 145 4 0.0275862068965517 0.0476190476190476
GO:BP GO:0045862 positive regulation of proteolysis 0.0211350085816343 378 99 7 0.0707070707070707 0.0185185185185185
GO:BP GO:0042157 lipoprotein metabolic process 0.0219903725660918 136 91 4 0.043956043956044 0.0294117647058824
GO:BP GO:0032612 interleukin-1 production 0.0225215385288871 126 99 4 0.0404040404040404 0.0317460317460317
GO:BP GO:0051090 regulation of DNA-binding transcription factor activity 0.0227124534756063 456 128 9 0.0703125 0.0197368421052632
GO:BP GO:0019538 protein metabolic process 0.0231222746591599 5808 85 39 0.458823529411765 0.00671487603305785
GO:BP GO:0065007 biological regulation 0.0232530176802922 12809 48 42 0.875 0.00327894449215395
GO:BP GO:0044267 cellular protein metabolic process 0.0232851571823072 5229 85 36 0.423529411764706 0.00688468158347676
GO:BP GO:0050798 activated T cell proliferation 0.023358354981149 49 131 3 0.0229007633587786 0.0612244897959184
GO:BP GO:0048872 homeostasis of number of cells 0.0234187124096531 261 78 5 0.0641025641025641 0.0191570881226054
GO:BP GO:0032680 regulation of tumor necrosis factor production 0.0234314264057273 163 78 4 0.0512820512820513 0.0245398773006135
GO:BP GO:0070482 response to oxygen levels 0.0238190287861948 408 32 4 0.125 0.00980392156862745
GO:BP GO:0043312 neutrophil degranulation 0.0238190287861948 482 101 8 0.0792079207920792 0.016597510373444
GO:BP GO:0043086 negative regulation of catalytic activity 0.0239140805135253 851 16 4 0.25 0.00470035252643948
GO:BP GO:0032640 tumor necrosis factor production 0.0239496084527786 165 78 4 0.0512820512820513 0.0242424242424242
GO:BP GO:0002283 neutrophil activation involved in immune response 0.0243544784677683 485 101 8 0.0792079207920792 0.0164948453608247
GO:BP GO:0031329 regulation of cellular catabolic process 0.0247807712137583 866 109 12 0.110091743119266 0.0138568129330254
GO:BP GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 0.0247807712137583 167 78 4 0.0512820512820513 0.0239520958083832
GO:BP GO:0048729 tissue morphogenesis 0.0248339160712398 667 32 5 0.15625 0.00749625187406297
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 0.0249819270531489 159 42 3 0.0714285714285714 0.0188679245283019
GO:BP GO:0032675 regulation of interleukin-6 production 0.0251089976096627 168 78 4 0.0512820512820513 0.0238095238095238
GO:BP GO:0042129 regulation of T cell proliferation 0.0255130776891316 176 119 5 0.0420168067226891 0.0284090909090909
GO:BP GO:0071706 tumor necrosis factor superfamily cytokine production 0.0255986890347181 170 78 4 0.0512820512820513 0.0235294117647059
GO:BP GO:0008283 cell population proliferation 0.0256214277858974 2054 138 26 0.188405797101449 0.0126582278481013
GO:BP GO:0033554 cellular response to stress 0.025894372716105 2111 47 12 0.25531914893617 0.00568450971103742
GO:BP GO:0032635 interleukin-6 production 0.0261379142962183 172 78 4 0.0512820512820513 0.0232558139534884
GO:BP GO:0002446 neutrophil mediated immunity 0.0263745791524029 497 101 8 0.0792079207920792 0.0160965794768612
GO:BP GO:0008637 apoptotic mitochondrial changes 0.0263798167786809 126 55 3 0.0545454545454545 0.0238095238095238
GO:BP GO:0042119 neutrophil activation 0.026526302936922 498 101 8 0.0792079207920792 0.0160642570281124
GO:BP GO:0032755 positive regulation of interleukin-6 production 0.026526302936922 89 78 3 0.0384615384615385 0.0337078651685393
GO:BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0266774782794702 217 99 5 0.0505050505050505 0.0230414746543779
GO:BP GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0271330780014486 138 99 4 0.0404040404040404 0.0289855072463768
GO:BP GO:0044093 positive regulation of molecular function 0.0274171554063927 1771 99 18 0.181818181818182 0.0101637492941841
GO:BP GO:0051234 establishment of localization 0.0274171554063927 5372 104 43 0.413461538461538 0.00800446760982874
GO:BP GO:0048524 positive regulation of viral process 0.0274171554063927 91 78 3 0.0384615384615385 0.032967032967033
GO:BP GO:0034656 nucleobase-containing small molecule catabolic process 0.0274171554063927 49 145 3 0.0206896551724138 0.0612244897959184
GO:BP GO:0036230 granulocyte activation 0.0274171554063927 504 101 8 0.0792079207920792 0.0158730158730159
GO:BP GO:0030522 intracellular receptor signaling pathway 0.0274171554063927 284 108 6 0.0555555555555556 0.0211267605633803
GO:BP GO:0051101 regulation of DNA binding 0.0274872144324077 121 59 3 0.0508474576271186 0.0247933884297521
GO:BP GO:0051099 positive regulation of binding 0.02795697902489 174 80 4 0.05 0.0229885057471264
GO:BP GO:0060341 regulation of cellular localization 0.0284741719398212 851 87 10 0.114942528735632 0.0117508813160987
GO:BP GO:0062012 regulation of small molecule metabolic process 0.0286157913449229 447 32 4 0.125 0.00894854586129754
GO:BP GO:1903131 mononuclear cell differentiation 0.0286840005971948 430 52 5 0.0961538461538462 0.0116279069767442
GO:BP GO:0051641 cellular localization 0.0289433969282466 3541 104 31 0.298076923076923 0.00875458909912454
GO:BP GO:1901990 regulation of mitotic cell cycle phase transition 0.0289433969282466 451 32 4 0.125 0.00886917960088692
GO:BP GO:0051649 establishment of localization in cell 0.0294285429904295 2813 104 26 0.25 0.00924280127977248
GO:BP GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling 0.029437915254157 636 36 5 0.138888888888889 0.00786163522012579
GO:BP GO:0050729 positive regulation of inflammatory response 0.0307526921565449 142 102 4 0.0392156862745098 0.028169014084507
GO:BP GO:0006959 humoral immune response 0.030838311033102 384 109 7 0.0642201834862385 0.0182291666666667
GO:BP GO:1901575 organic substance catabolic process 0.0312908459587573 2267 110 23 0.209090909090909 0.0101455668284076
GO:BP GO:1904427 positive regulation of calcium ion transmembrane transport 0.0315517194711001 74 104 3 0.0288461538461538 0.0405405405405405
GO:BP GO:0051252 regulation of RNA metabolic process 0.0315517194711001 3822 117 36 0.307692307692308 0.00941915227629513
GO:BP GO:0034504 protein localization to nucleus 0.0318886094388782 289 80 5 0.0625 0.0173010380622837
GO:BP GO:0009894 regulation of catabolic process 0.0319196137589523 1033 109 13 0.119266055045872 0.0125847047434656
GO:BP GO:0042110 T cell activation 0.0321307155134192 489 131 9 0.0687022900763359 0.0184049079754601
GO:BP GO:1903828 negative regulation of cellular protein localization 0.0329095956593419 116 68 3 0.0441176470588235 0.0258620689655172
GO:BP GO:0072678 T cell migration 0.0337874906696157 67 119 3 0.0252100840336134 0.0447761194029851
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.034043325829537 2541 4 3 0.75 0.00118063754427391
GO:BP GO:0046649 lymphocyte activation 0.0345959458219537 771 131 12 0.0916030534351145 0.0155642023346304
GO:BP GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 0.0347365316228513 71 114 3 0.0263157894736842 0.0422535211267606
GO:BP GO:0042102 positive regulation of T cell proliferation 0.0348810491326022 104 78 3 0.0384615384615385 0.0288461538461538
GO:BP GO:0051259 protein complex oligomerization 0.0354222375806185 234 66 4 0.0606060606060606 0.0170940170940171
GO:BP GO:1901987 regulation of cell cycle phase transition 0.0358091814304363 493 32 4 0.125 0.00811359026369168
GO:BP GO:1902531 regulation of intracellular signal transduction 0.0358091814304363 1842 114 20 0.175438596491228 0.01085776330076
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 0.0360864581324259 5848 4 4 1 0.000683994528043776
GO:BP GO:1904064 positive regulation of cation transmembrane transport 0.0363495859093336 150 104 4 0.0384615384615385 0.0266666666666667
GO:BP GO:0071675 regulation of mononuclear cell migration 0.0363495859093336 113 138 4 0.0289855072463768 0.0353982300884956
GO:BP GO:0042130 negative regulation of T cell proliferation 0.0363565289738819 70 119 3 0.0252100840336134 0.0428571428571429
GO:BP GO:2000106 regulation of leukocyte apoptotic process 0.036667830406749 82 102 3 0.0294117647058824 0.0365853658536585
GO:BP GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 0.0369946417528084 81 104 3 0.0288461538461538 0.037037037037037
GO:BP GO:0051051 negative regulation of transport 0.0370194104790164 474 52 5 0.0961538461538462 0.0105485232067511
GO:BP GO:0035821 modulation of process of other organism 0.0371071531028304 128 66 3 0.0454545454545455 0.0234375
GO:BP GO:0043393 regulation of protein binding 0.0377094491514262 199 80 4 0.05 0.0201005025125628
GO:BP GO:0006887 exocytosis 0.0382744451983992 904 101 11 0.108910891089109 0.0121681415929204
GO:BP GO:0050671 positive regulation of lymphocyte proliferation 0.0389060832438401 141 114 4 0.0350877192982456 0.0283687943262411
GO:BP GO:0080090 regulation of primary metabolic process 0.0396036490205249 6053 4 4 1 0.000660829340822732
GO:BP GO:0006898 receptor-mediated endocytosis 0.0396036490205249 333 49 4 0.0816326530612245 0.012012012012012
GO:BP GO:0032946 positive regulation of mononuclear cell proliferation 0.0396036490205249 142 114 4 0.0350877192982456 0.028169014084507
GO:BP GO:2000026 regulation of multicellular organismal development 0.039861344482274 1447 48 9 0.1875 0.00621976503109883
GO:BP GO:0071704 organic substance metabolic process 0.0403720548728817 11326 83 62 0.746987951807229 0.00547413031961858
GO:BP GO:0051279 regulation of release of sequestered calcium ion into cytosol 0.0404080860996876 85 104 3 0.0288461538461538 0.0352941176470588
GO:BP GO:0010564 regulation of cell cycle process 0.0404080860996876 809 44 6 0.136363636363636 0.00741656365883807
GO:BP GO:0034654 nucleobase-containing compound biosynthetic process 0.0408356482094745 4199 50 19 0.38 0.00452488687782805
GO:BP GO:0001525 angiogenesis 0.0419082825138172 617 42 5 0.119047619047619 0.00810372771474878
GO:BP GO:0070098 chemokine-mediated signaling pathway 0.042427036094736 87 104 3 0.0288461538461538 0.0344827586206897
GO:BP GO:0031323 regulation of cellular metabolic process 0.0436010502275367 6269 4 4 1 0.000638060296698038
GO:BP GO:0002526 acute inflammatory response 0.0440557763732689 114 81 3 0.037037037037037 0.0263157894736842
GO:BP GO:0010941 regulation of cell death 0.0459818608223343 1720 102 17 0.166666666666667 0.00988372093023256
GO:BP GO:0071674 mononuclear cell migration 0.0464309355071069 191 138 5 0.036231884057971 0.0261780104712042
GO:BP GO:0006464 cellular protein modification process 0.0464855263941802 4041 85 28 0.329411764705882 0.00692897797574858
GO:BP GO:0036211 protein modification process 0.0464855263941802 4041 85 28 0.329411764705882 0.00692897797574858
GO:BP GO:0018130 heterocycle biosynthetic process 0.0465472219759591 4269 50 19 0.38 0.00445069102834387
GO:BP GO:0031400 negative regulation of protein modification process 0.0465855002408021 578 82 7 0.0853658536585366 0.0121107266435986
GO:BP GO:0061024 membrane organization 0.0468315581301161 973 61 8 0.131147540983607 0.00822199383350463
GO:BP GO:0019438 aromatic compound biosynthetic process 0.0471809019001588 4278 50 19 0.38 0.00444132772323516
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.0472087146877287 549 18 3 0.166666666666667 0.00546448087431694
GO:BP GO:0051179 localization 0.0486717966542704 6901 68 35 0.514705882352941 0.00507172873496595
GO:BP GO:0033365 protein localization to organelle 0.0499182244308706 1017 95 11 0.115789473684211 0.0108161258603736
GO:CC GO:0042612 MHC class I protein complex 1.17396088417641e-11 8 65 6 0.0923076923076923 0.75
GO:CC GO:0030670 phagocytic vesicle membrane 7.19580085684253e-10 76 65 9 0.138461538461538 0.118421052631579
GO:CC GO:0042824 MHC class I peptide loading complex 2.99156068227257e-09 9 61 5 0.0819672131147541 0.555555555555556
GO:CC GO:0045335 phagocytic vesicle 2.99156068227257e-09 137 65 10 0.153846153846154 0.072992700729927
GO:CC GO:0042611 MHC protein complex 1.01366167201627e-08 24 65 6 0.0923076923076923 0.25
GO:CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 1.01366167201627e-08 25 65 6 0.0923076923076923 0.24
GO:CC GO:0098553 lumenal side of endoplasmic reticulum membrane 1.01366167201627e-08 25 65 6 0.0923076923076923 0.24
GO:CC GO:0005829 cytosol 2.26521771135238e-08 5303 106 60 0.566037735849057 0.0113143503677164
GO:CC GO:0098576 lumenal side of membrane 4.82636450978973e-08 33 65 6 0.0923076923076923 0.181818181818182
GO:CC GO:0030666 endocytic vesicle membrane 1.04587495555547e-07 159 65 9 0.138461538461538 0.0566037735849057
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 1.04587495555547e-07 158 65 9 0.138461538461538 0.0569620253164557
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 1.40044596571931e-07 166 65 9 0.138461538461538 0.0542168674698795
GO:CC GO:0012507 ER to Golgi transport vesicle membrane 9.77272562022423e-07 57 65 6 0.0923076923076923 0.105263157894737
GO:CC GO:0005737 cytoplasm 9.77272562022423e-07 11911 75 68 0.906666666666667 0.00570900847955671
GO:CC GO:0030139 endocytic vesicle 1.85528276521506e-06 306 65 10 0.153846153846154 0.0326797385620915
GO:CC GO:0055038 recycling endosome membrane 2.53861515290819e-06 84 88 7 0.0795454545454545 0.0833333333333333
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 1.23357265548698e-05 90 65 6 0.0923076923076923 0.0666666666666667
GO:CC GO:1990111 spermatoproteasome complex 3.35012737460852e-05 5 109 3 0.0275229357798165 0.6
GO:CC GO:0000502 proteasome complex 3.73611313215717e-05 66 109 6 0.055045871559633 0.0909090909090909
GO:CC GO:1905369 endopeptidase complex 5.47054162086053e-05 72 109 6 0.055045871559633 0.0833333333333333
GO:CC GO:0010008 endosome membrane 5.47054162086053e-05 505 88 12 0.136363636363636 0.0237623762376238
GO:CC GO:0031982 vesicle 5.47054162086053e-05 4055 40 22 0.55 0.00542540073982737
GO:CC GO:0031901 early endosome membrane 6.94993360934555e-05 159 80 7 0.0875 0.0440251572327044
GO:CC GO:0031301 integral component of organelle membrane 8.06047006452439e-05 382 65 9 0.138461538461538 0.0235602094240838
GO:CC GO:0005839 proteasome core complex 0.000106447543567879 23 109 4 0.036697247706422 0.173913043478261
GO:CC GO:0031300 intrinsic component of organelle membrane 0.000134028972689845 413 65 9 0.138461538461538 0.0217917675544794
GO:CC GO:1905368 peptidase complex 0.000217237027883107 96 109 6 0.055045871559633 0.0625
GO:CC GO:0030662 coated vesicle membrane 0.000235715189426167 177 37 5 0.135135135135135 0.0282485875706215
GO:CC GO:0031410 cytoplasmic vesicle 0.000235715189426167 2424 68 22 0.323529411764706 0.00907590759075908
GO:CC GO:0097708 intracellular vesicle 0.000235715189426167 2428 68 22 0.323529411764706 0.00906095551894563
GO:CC GO:0098552 side of membrane 0.000248156629393557 619 131 15 0.114503816793893 0.024232633279483
GO:CC GO:0055037 recycling endosome 0.000255469648288569 188 88 7 0.0795454545454545 0.0372340425531915
GO:CC GO:0019774 proteasome core complex, beta-subunit complex 0.000269510876889862 11 109 3 0.0275229357798165 0.272727272727273
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.000281580041395341 11296 83 67 0.807228915662651 0.00593130311614731
GO:CC GO:0098791 Golgi apparatus subcompartment 0.000325287992875483 885 37 9 0.243243243243243 0.0101694915254237
GO:CC GO:0031981 nuclear lumen 0.000329472595525752 4444 98 41 0.418367346938776 0.00922592259225923
GO:CC GO:0005768 endosome 0.000332539354533505 987 68 13 0.191176470588235 0.0131712259371834
GO:CC GO:0030658 transport vesicle membrane 0.000397550663090668 209 37 5 0.135135135135135 0.0239234449760766
GO:CC GO:0140534 endoplasmic reticulum protein-containing complex 0.000435991956801381 128 61 5 0.0819672131147541 0.0390625
GO:CC GO:0005794 Golgi apparatus 0.000487259313125734 1623 39 12 0.307692307692308 0.00739371534195933
GO:CC GO:0000139 Golgi membrane 0.000500917229109272 771 90 13 0.144444444444444 0.0168612191958495
GO:CC GO:0012506 vesicle membrane 0.000561083264122075 800 65 11 0.169230769230769 0.01375
GO:CC GO:0031984 organelle subcompartment 0.000592259612690176 1773 37 12 0.324324324324324 0.00676818950930626
GO:CC GO:0005654 nucleoplasm 0.000592259612690176 4102 98 38 0.387755102040816 0.00926377376889322
GO:CC GO:0009897 external side of plasma membrane 0.000846082965093415 408 131 11 0.083969465648855 0.0269607843137255
GO:CC GO:0043229 intracellular organelle 0.000893450044183787 12491 83 70 0.843373493975904 0.0056040349051317
GO:CC GO:0098588 bounding membrane of organelle 0.000928791386438352 2158 68 19 0.279411764705882 0.00880444856348471
GO:CC GO:0070062 extracellular exosome 0.00109858671661617 2176 33 12 0.363636363636364 0.00551470588235294
GO:CC GO:0043233 organelle lumen 0.00109924834556769 5565 139 61 0.438848920863309 0.0109613656783468
GO:CC GO:0031974 membrane-enclosed lumen 0.00109924834556769 5565 139 61 0.438848920863309 0.0109613656783468
GO:CC GO:0005769 early endosome 0.00112986099301238 378 80 8 0.1 0.0211640211640212
GO:CC GO:0043230 extracellular organelle 0.00139970989688699 2263 33 12 0.363636363636364 0.00530269553689792
GO:CC GO:1903561 extracellular vesicle 0.00139970989688699 2261 33 12 0.363636363636364 0.00530738611233967
GO:CC GO:0070013 intracellular organelle lumen 0.00139970989688699 5402 83 39 0.469879518072289 0.00721954831543873
GO:CC GO:0030135 coated vesicle 0.00139970989688699 295 37 5 0.135135135135135 0.0169491525423729
GO:CC GO:0005622 intracellular anatomical structure 0.00146485893456848 14790 83 77 0.927710843373494 0.00520622041920216
GO:CC GO:0012505 endomembrane system 0.00146485893456848 4640 56 26 0.464285714285714 0.00560344827586207
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.0015360655307054 779 65 10 0.153846153846154 0.0128369704749679
GO:CC GO:0005789 endoplasmic reticulum membrane 0.00184274443742245 1117 65 12 0.184615384615385 0.0107430617726052
GO:CC GO:0098827 endoplasmic reticulum subcompartment 0.00188984141268482 1122 65 12 0.184615384615385 0.0106951871657754
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 0.00213266101643513 1139 65 12 0.184615384615385 0.0105355575065847
GO:CC GO:0048471 perinuclear region of cytoplasm 0.00223751563435622 735 48 8 0.166666666666667 0.0108843537414966
GO:CC GO:0005576 extracellular region 0.00223751563435622 4567 38 19 0.5 0.00416028027151303
GO:CC GO:0009986 cell surface 0.00284661621894878 899 134 16 0.119402985074627 0.017797552836485
GO:CC GO:0005634 nucleus 0.0034972823185373 7592 83 48 0.578313253012048 0.00632244467860906
GO:CC GO:0005615 extracellular space 0.00387583123473022 3594 71 25 0.352112676056338 0.00695603784084585
GO:CC GO:0043227 membrane-bounded organelle 0.00387583123473022 12858 72 61 0.847222222222222 0.00474412816923316
GO:CC GO:1904724 tertiary granule lumen 0.00391738780348892 55 66 3 0.0454545454545455 0.0545454545454545
GO:CC GO:0030133 transport vesicle 0.00488429384456808 414 37 5 0.135135135135135 0.0120772946859903
GO:CC GO:0031090 organelle membrane 0.00690438984576709 3612 40 16 0.4 0.0044296788482835
GO:CC GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 0.00692126303544866 74 61 3 0.0491803278688525 0.0405405405405405
GO:CC GO:0031904 endosome lumen 0.00815575371478402 35 138 3 0.0217391304347826 0.0857142857142857
GO:CC GO:0005783 endoplasmic reticulum 0.00945843812482236 1982 65 15 0.230769230769231 0.00756811301715439
GO:CC GO:0031966 mitochondrial membrane 0.0109495539523412 746 8 3 0.375 0.00402144772117962
GO:CC GO:0005770 late endosome 0.011288073443799 275 68 5 0.0735294117647059 0.0181818181818182
GO:CC GO:0043226 organelle 0.0126439251003165 14008 83 72 0.867469879518072 0.00513992004568818
GO:CC GO:0005740 mitochondrial envelope 0.0126439251003165 797 8 3 0.375 0.00376411543287327
GO:CC GO:0022626 cytosolic ribosome 0.0197904392743752 109 63 3 0.0476190476190476 0.0275229357798165
GO:CC GO:0005739 mitochondrion 0.0278673824692173 1673 10 4 0.4 0.00239091452480574
GO:CC GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 0.0288847591356591 131 61 3 0.0491803278688525 0.0229007633587786
GO:CC GO:0140535 intracellular protein-containing complex 0.0288847591356591 767 32 5 0.15625 0.00651890482398957
GO:CC GO:0098852 lytic vacuole membrane 0.0295303937431787 383 116 7 0.0603448275862069 0.0182767624020888
GO:CC GO:0005765 lysosomal membrane 0.0295303937431787 383 116 7 0.0603448275862069 0.0182767624020888
GO:CC GO:0005730 nucleolus 0.0301426384904873 955 97 11 0.11340206185567 0.0115183246073298
GO:CC GO:0030667 secretory granule membrane 0.0302903364471859 303 28 3 0.107142857142857 0.0099009900990099
GO:CC GO:0070820 tertiary granule 0.0302903364471859 163 97 4 0.0412371134020619 0.0245398773006135
GO:CC GO:0098797 plasma membrane protein complex 0.0323104964229168 694 37 5 0.135135135135135 0.00720461095100865
GO:CC GO:0031975 envelope 0.035550677322872 1237 8 3 0.375 0.00242522231204527
GO:CC GO:0031967 organelle envelope 0.035550677322872 1237 8 3 0.375 0.00242522231204527
GO:CC GO:0005774 vacuolar membrane 0.0364735441962264 441 133 8 0.0601503759398496 0.018140589569161
GO:CC GO:0101002 ficolin-1-rich granule 0.039103624853189 184 146 5 0.0342465753424658 0.0271739130434783
GO:CC GO:1904813 ficolin-1-rich granule lumen 0.0418989527109936 124 146 4 0.0273972602739726 0.032258064516129
GO:CC GO:0016020 membrane 0.0447616822152495 9838 81 52 0.641975308641975 0.00528562715999187
GO:MF GO:0046977 TAP binding 4.33786322190789e-14 9 61 7 0.114754098360656 0.777777777777778
GO:MF GO:0042605 peptide antigen binding 1.65510507697682e-11 30 65 8 0.123076923076923 0.266666666666667
GO:MF GO:0003725 double-stranded RNA binding 3.15686151935354e-09 77 108 10 0.0925925925925926 0.12987012987013
GO:MF GO:0001730 2'-5'-oligoadenylate synthetase activity 5.25195447851144e-08 4 89 4 0.0449438202247191 1
GO:MF GO:0046978 TAP1 binding 1.34044543828621e-07 6 61 4 0.0655737704918033 0.666666666666667
GO:MF GO:0046979 TAP2 binding 2.13151214921076e-06 3 61 3 0.0491803278688525 1
GO:MF GO:0003724 RNA helicase activity 2.13151214921076e-06 76 122 8 0.0655737704918033 0.105263157894737
GO:MF GO:0003823 antigen binding 5.11016278561378e-06 163 65 8 0.123076923076923 0.049079754601227
GO:MF GO:0042802 identical protein binding 7.19976418522716e-06 2067 42 18 0.428571428571429 0.00870827285921625
GO:MF GO:0042803 protein homodimerization activity 8.6367853437492e-06 676 42 11 0.261904761904762 0.0162721893491124
GO:MF GO:0015440 ABC-type peptide transporter activity 1.19903214961514e-05 5 61 3 0.0491803278688525 0.6
GO:MF GO:0015433 ABC-type peptide antigen transporter activity 1.19903214961514e-05 5 61 3 0.0491803278688525 0.6
GO:MF GO:0042288 MHC class I protein binding 2.08204892164588e-05 20 65 4 0.0615384615384615 0.2
GO:MF GO:0017111 nucleoside-triphosphatase activity 2.81605427169367e-05 872 122 20 0.163934426229508 0.0229357798165138
GO:MF GO:0004386 helicase activity 3.20289749072355e-05 162 122 9 0.0737704918032787 0.0555555555555556
GO:MF GO:1990404 protein ADP-ribosylase activity 3.20289749072355e-05 16 96 4 0.0416666666666667 0.25
GO:MF GO:0030881 beta-2-microglobulin binding 3.57624369357555e-05 7 65 3 0.0461538461538462 0.428571428571429
GO:MF GO:0048248 CXCR3 chemokine receptor binding 4.03062652401282e-05 5 104 3 0.0288461538461538 0.6
GO:MF GO:0016462 pyrophosphatase activity 5.04773610516661e-05 928 122 20 0.163934426229508 0.021551724137931
GO:MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 5.04773610516661e-05 930 122 20 0.163934426229508 0.021505376344086
GO:MF GO:0016817 hydrolase activity, acting on acid anhydrides 5.04773610516661e-05 930 122 20 0.163934426229508 0.021505376344086
GO:MF GO:0042287 MHC protein binding 0.000183246333427402 39 65 4 0.0615384615384615 0.102564102564103
GO:MF GO:0003950 NAD+ ADP-ribosyltransferase activity 0.000183246333427402 27 96 4 0.0416666666666667 0.148148148148148
GO:MF GO:0016763 transferase activity, transferring pentosyl groups 0.000183246333427402 56 96 5 0.0520833333333333 0.0892857142857143
GO:MF GO:0042277 peptide binding 0.00021503629335129 314 65 8 0.123076923076923 0.0254777070063694
GO:MF GO:0046983 protein dimerization activity 0.000274638264585082 1069 42 11 0.261904761904762 0.010289990645463
GO:MF GO:0070566 adenylyltransferase activity 0.000276234614872223 33 89 4 0.0449438202247191 0.121212121212121
GO:MF GO:0016887 ATPase activity 0.000279064526678866 488 122 13 0.10655737704918 0.0266393442622951
GO:MF GO:0016787 hydrolase activity 0.000457434276300539 2615 145 39 0.268965517241379 0.0149139579349904
GO:MF GO:0044389 ubiquitin-like protein ligase binding 0.000464425491910622 314 119 10 0.0840336134453782 0.0318471337579618
GO:MF GO:0140098 catalytic activity, acting on RNA 0.000476721207121 395 137 12 0.0875912408759124 0.030379746835443
GO:MF GO:0097367 carbohydrate derivative binding 0.000670603808496929 2285 95 26 0.273684210526316 0.0113785557986871
GO:MF GO:0140359 ABC-type transporter activity 0.00069933773492172 23 61 3 0.0491803278688525 0.130434782608696
GO:MF GO:0033218 amide binding 0.00069933773492172 389 65 8 0.123076923076923 0.0205655526992288
GO:MF GO:0003727 single-stranded RNA binding 0.00069933773492172 92 137 6 0.0437956204379562 0.0652173913043478
GO:MF GO:0005525 GTP binding 0.00069933773492172 381 34 6 0.176470588235294 0.015748031496063
GO:MF GO:0032549 ribonucleoside binding 0.00070291785429477 389 34 6 0.176470588235294 0.0154241645244216
GO:MF GO:0001883 purine nucleoside binding 0.00070291785429477 389 34 6 0.176470588235294 0.0154241645244216
GO:MF GO:0032550 purine ribonucleoside binding 0.00070291785429477 386 34 6 0.176470588235294 0.0155440414507772
GO:MF GO:0004298 threonine-type endopeptidase activity 0.000714329555678513 14 109 3 0.0275229357798165 0.214285714285714
GO:MF GO:0001882 nucleoside binding 0.000728587314548963 395 34 6 0.176470588235294 0.0151898734177215
GO:MF GO:0019001 guanyl nucleotide binding 0.00075961834805067 403 34 6 0.176470588235294 0.0148883374689826
GO:MF GO:0032561 guanyl ribonucleotide binding 0.00075961834805067 403 34 6 0.176470588235294 0.0148883374689826
GO:MF GO:0005515 protein binding 0.00075961834805067 14767 139 127 0.913669064748201 0.0086002573305343
GO:MF GO:0045236 CXCR chemokine receptor binding 0.00121936845753327 18 104 3 0.0288461538461538 0.166666666666667
GO:MF GO:0003824 catalytic activity 0.00171022041169805 5896 110 53 0.481818181818182 0.00898914518317503
GO:MF GO:0035639 purine ribonucleoside triphosphate binding 0.00189924445872588 1847 126 26 0.206349206349206 0.0140768814293449
GO:MF GO:1904680 peptide transmembrane transporter activity 0.00199563799825481 37 61 3 0.0491803278688525 0.0810810810810811
GO:MF GO:0005488 binding 0.00221792121762648 17074 143 141 0.986013986013986 0.00825817031744172
GO:MF GO:0003723 RNA binding 0.00232988566171014 1943 122 26 0.213114754098361 0.013381369016984
GO:MF GO:0003924 GTPase activity 0.0023526202981176 328 34 5 0.147058823529412 0.0152439024390244
GO:MF GO:0070003 threonine-type peptidase activity 0.00278704846070516 24 109 3 0.0275229357798165 0.125
GO:MF GO:0032555 purine ribonucleotide binding 0.00306688505575266 1918 126 26 0.206349206349206 0.013555787278415
GO:MF GO:0017076 purine nucleotide binding 0.00339377467675735 1933 126 26 0.206349206349206 0.0134505949301604
GO:MF GO:0032553 ribonucleotide binding 0.00339377467675735 1935 126 26 0.206349206349206 0.0134366925064599
GO:MF GO:0042379 chemokine receptor binding 0.00475576669294444 72 104 4 0.0384615384615385 0.0555555555555556
GO:MF GO:0004842 ubiquitin-protein transferase activity 0.00559269184852512 442 126 10 0.0793650793650794 0.0226244343891403
GO:MF GO:0042887 amide transmembrane transporter activity 0.0059469862941142 58 61 3 0.0491803278688525 0.0517241379310345
GO:MF GO:1901265 nucleoside phosphate binding 0.00745486802338486 2172 126 27 0.214285714285714 0.0124309392265193
GO:MF GO:0000166 nucleotide binding 0.00745486802338486 2171 126 27 0.214285714285714 0.0124366651312759
GO:MF GO:0019787 ubiquitin-like protein transferase activity 0.0077246519836591 465 126 10 0.0793650793650794 0.021505376344086
GO:MF GO:0005102 signaling receptor binding 0.00828888313454737 1672 93 18 0.193548387096774 0.0107655502392345
GO:MF GO:0042626 ATPase-coupled transmembrane transporter activity 0.00828888313454737 67 61 3 0.0491803278688525 0.0447761194029851
GO:MF GO:0016504 peptidase activator activity 0.00852696862855532 42 99 3 0.0303030303030303 0.0714285714285714
GO:MF GO:0043168 anion binding 0.0105635747555684 2418 57 16 0.280701754385965 0.00661703887510339
GO:MF GO:0015399 primary active transmembrane transporter activity 0.0105635747555684 74 61 3 0.0491803278688525 0.0405405405405405
GO:MF GO:0008009 chemokine activity 0.0141629005257674 49 104 3 0.0288461538461538 0.0612244897959184
GO:MF GO:0016779 nucleotidyltransferase activity 0.016788420402844 135 137 5 0.0364963503649635 0.037037037037037
GO:MF GO:0036094 small molecule binding 0.0196783559565216 2506 108 25 0.231481481481481 0.00997605746209098
GO:MF GO:0061135 endopeptidase regulator activity 0.0196783559565216 188 32 3 0.09375 0.0159574468085106
GO:MF GO:0004175 endopeptidase activity 0.0225810059007106 450 109 8 0.073394495412844 0.0177777777777778
GO:MF GO:0005524 ATP binding 0.0256065504141147 1501 126 19 0.150793650793651 0.0126582278481013
GO:MF GO:0003714 transcription corepressor activity 0.0265739329990752 187 115 5 0.0434782608695652 0.0267379679144385
GO:MF GO:0061134 peptidase regulator activity 0.0279313564229851 224 32 3 0.09375 0.0133928571428571
GO:MF GO:0003712 transcription coregulator activity 0.0335779760388953 506 85 7 0.0823529411764706 0.0138339920948617
GO:MF GO:0140096 catalytic activity, acting on a protein 0.0344038532604709 2332 110 23 0.209090909090909 0.00986277873070326
GO:MF GO:0032559 adenyl ribonucleotide binding 0.0346943028330878 1565 126 19 0.150793650793651 0.0121405750798722
GO:MF GO:0030554 adenyl nucleotide binding 0.0368171933392402 1578 126 19 0.150793650793651 0.0120405576679341
GO:MF GO:0098772 molecular function regulator 0.0384842247505026 2363 104 22 0.211538461538462 0.00931019889970377
GO:MF GO:0005125 cytokine activity 0.0384842247505026 235 104 5 0.0480769230769231 0.0212765957446809
GO:MF GO:0008233 peptidase activity 0.0405158770131663 646 143 11 0.0769230769230769 0.0170278637770898
GO:MF GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 0.0405581896377767 281 89 5 0.0561797752808989 0.0177935943060498
GO:MF GO:0031625 ubiquitin protein ligase binding 0.0423973882013382 296 119 6 0.0504201680672269 0.0202702702702703
GO:MF GO:0004197 cysteine-type endopeptidase activity 0.0438257117631682 121 138 4 0.0289855072463768 0.0330578512396694
GO:MF GO:1901363 heterocyclic compound binding 0.045085673258502 6228 58 28 0.482758620689655 0.00449582530507386
GO:MF GO:0016757 transferase activity, transferring glycosyl groups 0.0494352331107777 283 96 5 0.0520833333333333 0.0176678445229682
GO:MF GO:0097159 organic cyclic compound binding 0.0494352331107777 6309 58 28 0.482758620689655 0.00443810429545094
HP HP:0030355 Abnormal serum interferon-gamma level 0.000278315189510371 11 72 5 0.0694444444444444 0.454545454545455
HP HP:0030354 Abnormal serum interferon level 0.000278315189510371 11 72 5 0.0694444444444444 0.454545454545455
HP HP:0011112 Abnormality of serum cytokine level 0.0108818932206392 23 72 5 0.0694444444444444 0.217391304347826
HP HP:0011111 Abnormality of immune serum protein physiology 0.0108818932206392 24 72 5 0.0694444444444444 0.208333333333333
HP HP:0011948 Recurrent acute respiratory tract infection 0.0188568995034379 7 61 3 0.0491803278688525 0.428571428571429
HP HP:0011950 Bronchiolitis 0.0188568995034379 7 61 3 0.0491803278688525 0.428571428571429
HP HP:0030356 Increased serum interferon-gamma level 0.042048405885573 8 72 3 0.0416666666666667 0.375
KEGG KEGG:05169 Epstein-Barr virus infection 7.04643668834009e-13 198 73 19 0.26027397260274 0.095959595959596
KEGG KEGG:04612 Antigen processing and presentation 9.91143872716117e-12 69 65 12 0.184615384615385 0.173913043478261
KEGG KEGG:05164 Influenza A 6.86625570679073e-10 169 99 17 0.171717171717172 0.100591715976331
KEGG KEGG:04621 NOD-like receptor signaling pathway 1.07819167434215e-08 177 99 16 0.161616161616162 0.0903954802259887
KEGG KEGG:05160 Hepatitis C 2.74211605695164e-08 157 73 13 0.178082191780822 0.0828025477707006
KEGG KEGG:05162 Measles 6.56729968118256e-08 139 73 12 0.164383561643836 0.0863309352517986
KEGG KEGG:05168 Herpes simplex virus 1 infection 1.4283691111767e-07 494 73 20 0.273972602739726 0.0404858299595142
KEGG KEGG:05171 Coronavirus disease - COVID-19 2.17190341128148e-07 231 73 14 0.191780821917808 0.0606060606060606
KEGG KEGG:05170 Human immunodeficiency virus 1 infection 7.93562542398358e-05 210 65 10 0.153846153846154 0.0476190476190476
KEGG KEGG:05330 Allograft rejection 7.93562542398358e-05 34 65 5 0.0769230769230769 0.147058823529412
KEGG KEGG:05332 Graft-versus-host disease 0.000110910874162084 37 65 5 0.0769230769230769 0.135135135135135
KEGG KEGG:04940 Type I diabetes mellitus 0.000150619498772471 40 65 5 0.0769230769230769 0.125
KEGG KEGG:04145 Phagosome 0.000194234957147909 147 65 8 0.123076923076923 0.054421768707483
KEGG KEGG:03050 Proteasome 0.000246752433567434 46 32 4 0.125 0.0869565217391304
KEGG KEGG:05165 Human papillomavirus infection 0.000260018268949762 331 41 9 0.219512195121951 0.027190332326284
KEGG KEGG:05167 Kaposi sarcoma-associated herpesvirus infection 0.000291248721404368 193 70 9 0.128571428571429 0.0466321243523316
KEGG KEGG:05320 Autoimmune thyroid disease 0.000291248721404368 49 65 5 0.0769230769230769 0.102040816326531
KEGG KEGG:05163 Human cytomegalovirus infection 0.000445843543675207 223 65 9 0.138461538461538 0.0403587443946188
KEGG KEGG:05203 Viral carcinogenesis 0.00044643597803998 202 42 7 0.166666666666667 0.0346534653465347
KEGG KEGG:05416 Viral myocarditis 0.000474682673633256 56 65 5 0.0769230769230769 0.0892857142857143
KEGG KEGG:04622 RIG-I-like receptor signaling pathway 0.00184207727135135 70 108 6 0.0555555555555556 0.0857142857142857
KEGG KEGG:04217 Necroptosis 0.00387656706313707 159 99 8 0.0808080808080808 0.050314465408805
KEGG KEGG:04623 Cytosolic DNA-sensing pathway 0.00476824493002808 62 99 5 0.0505050505050505 0.0806451612903226
KEGG KEGG:04650 Natural killer cell mediated cytotoxicity 0.0123416526566791 123 38 4 0.105263157894737 0.032520325203252
KEGG KEGG:05166 Human T-cell leukemia virus 1 infection 0.0133383799595605 216 37 5 0.135135135135135 0.0231481481481481
KEGG KEGG:04620 Toll-like receptor signaling pathway 0.014147827665441 102 114 6 0.0526315789473684 0.0588235294117647
KEGG KEGG:04514 Cell adhesion molecules 0.0184243151476046 146 37 4 0.108108108108108 0.0273972602739726
KEGG KEGG:04218 Cellular senescence 0.02246885242854 156 37 4 0.108108108108108 0.0256410256410256
KEGG KEGG:04144 Endocytosis 0.0462672479294793 252 44 5 0.113636363636364 0.0198412698412698
MIRNA MIRNA:hsa-miR-146a-5p hsa-miR-146a-5p 1.4947791202218e-13 200 75 17 0.226666666666667 0.085
REAC REAC:R-HSA-909733 Interferon alpha/beta signaling 8.83717834964702e-47 66 98 32 0.326530612244898 0.484848484848485
REAC REAC:R-HSA-913531 Interferon Signaling 8.83717834964702e-47 191 75 39 0.52 0.204188481675393
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 1.78319158082615e-27 842 78 45 0.576923076923077 0.0534441805225653
REAC REAC:R-HSA-168256 Immune System 1.35445647046911e-20 2139 109 69 0.63302752293578 0.032258064516129
REAC REAC:R-HSA-877300 Interferon gamma signaling 5.64786891915565e-18 87 98 18 0.183673469387755 0.206896551724138
REAC REAC:R-HSA-1236975 Antigen processing-Cross presentation 5.16418426396705e-14 99 65 14 0.215384615384615 0.141414141414141
REAC REAC:R-HSA-1236974 ER-Phagosome pathway 1.32989952228136e-13 83 65 13 0.2 0.156626506024096
REAC REAC:R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 7.47773947163443e-13 25 65 9 0.138461538461538 0.36
REAC REAC:R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 7.47773947163443e-13 78 126 15 0.119047619047619 0.192307692307692
REAC REAC:R-HSA-1236977 Endosomal/Vacuolar pathway 3.68615205044708e-12 11 65 7 0.107692307692308 0.636363636363636
REAC REAC:R-HSA-983169 Class I MHC mediated antigen processing & presentation 5.18309923456917e-11 370 126 25 0.198412698412698 0.0675675675675676
REAC REAC:R-HSA-1169408 ISG15 antiviral mechanism 2.12820125016269e-08 70 126 11 0.0873015873015873 0.157142857142857
REAC REAC:R-HSA-8983711 OAS antiviral response 1.69404246648814e-07 9 89 5 0.0561797752808989 0.555555555555556
REAC REAC:R-HSA-1280218 Adaptive Immune System 2.58537615592416e-07 800 138 32 0.231884057971014 0.04
REAC REAC:R-HSA-8939902 Regulation of RUNX2 expression and activity 6.56395065838385e-05 71 32 5 0.15625 0.0704225352112676
REAC REAC:R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 7.74904898458113e-05 34 126 6 0.0476190476190476 0.176470588235294
REAC REAC:R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 8.77097320041535e-05 76 126 8 0.0634920634920635 0.105263157894737
REAC REAC:R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 9.85389674972995e-05 308 126 15 0.119047619047619 0.0487012987012987
REAC REAC:R-HSA-69610 p53-Independent DNA Damage Response 0.000255525149911623 52 109 6 0.055045871559633 0.115384615384615
REAC REAC:R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 0.000255525149911623 50 109 6 0.055045871559633 0.12
REAC REAC:R-HSA-69613 p53-Independent G1/S DNA damage checkpoint 0.000255525149911623 52 109 6 0.055045871559633 0.115384615384615
REAC REAC:R-HSA-180534 Vpu mediated degradation of CD4 0.000255525149911623 52 109 6 0.055045871559633 0.115384615384615
REAC REAC:R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 0.000255525149911623 52 109 6 0.055045871559633 0.115384615384615
REAC REAC:R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 0.000255525149911623 52 109 6 0.055045871559633 0.115384615384615
REAC REAC:R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 0.000255525149911623 51 109 6 0.055045871559633 0.117647058823529
REAC REAC:R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 0.000255525149911623 52 109 6 0.055045871559633 0.115384615384615
REAC REAC:R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 0.000255525149911623 50 109 6 0.055045871559633 0.12
REAC REAC:R-HSA-169911 Regulation of Apoptosis 0.00025716809481096 53 109 6 0.055045871559633 0.113207547169811
REAC REAC:R-HSA-180585 Vif-mediated degradation of APOBEC3G 0.00025716809481096 53 109 6 0.055045871559633 0.113207547169811
REAC REAC:R-HSA-9604323 Negative regulation of NOTCH4 signaling 0.00025716809481096 53 109 6 0.055045871559633 0.113207547169811
REAC REAC:R-HSA-8941858 Regulation of RUNX3 expression and activity 0.000268970222605965 54 109 6 0.055045871559633 0.111111111111111
REAC REAC:R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 0.000268970222605965 54 109 6 0.055045871559633 0.111111111111111
REAC REAC:R-HSA-4641257 Degradation of AXIN 0.00027372626074582 55 109 6 0.055045871559633 0.109090909090909
REAC REAC:R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 0.00027372626074582 55 109 6 0.055045871559633 0.109090909090909
REAC REAC:R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 0.00027372626074582 55 109 6 0.055045871559633 0.109090909090909
REAC REAC:R-HSA-5362768 Hh mutants are degraded by ERAD 0.000295572587898248 56 109 6 0.055045871559633 0.107142857142857
REAC REAC:R-HSA-4641258 Degradation of DVL 0.000295608226772543 57 32 4 0.125 0.0701754385964912
REAC REAC:R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 0.000295608226772543 60 32 4 0.125 0.0666666666666667
REAC REAC:R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 0.000295608226772543 59 32 4 0.125 0.0677966101694915
REAC REAC:R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 0.000295608226772543 60 32 4 0.125 0.0666666666666667
REAC REAC:R-HSA-5610783 Degradation of GLI2 by the proteasome 0.000295608226772543 60 32 4 0.125 0.0666666666666667
REAC REAC:R-HSA-5387390 Hh mutants abrogate ligand secretion 0.000295608226772543 59 32 4 0.125 0.0677966101694915
REAC REAC:R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 0.000295608226772543 60 32 4 0.125 0.0666666666666667
REAC REAC:R-HSA-5610780 Degradation of GLI1 by the proteasome 0.000295608226772543 60 32 4 0.125 0.0666666666666667
REAC REAC:R-HSA-351202 Metabolism of polyamines 0.000295608226772543 58 32 4 0.125 0.0689655172413793
REAC REAC:R-HSA-8878166 Transcriptional regulation by RUNX2 0.000295608226772543 118 32 5 0.15625 0.0423728813559322
REAC REAC:R-HSA-5676590 NIK-->noncanonical NF-kB signaling 0.000295608226772543 59 32 4 0.125 0.0677966101694915
REAC REAC:R-HSA-69541 Stabilization of p53 0.000295608226772543 57 32 4 0.125 0.0701754385964912
REAC REAC:R-HSA-5678895 Defective CFTR causes cystic fibrosis 0.000309238244730279 61 32 4 0.125 0.0655737704918033
REAC REAC:R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 0.00033018570784752 181 37 6 0.162162162162162 0.0331491712707182
REAC REAC:R-HSA-162909 Host Interactions of HIV factors 0.000348016446208345 125 33 5 0.151515151515152 0.04
REAC REAC:R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 0.000348016446208345 64 32 4 0.125 0.0625
REAC REAC:R-HSA-4608870 Asymmetric localization of PCP proteins 0.000348016446208345 64 32 4 0.125 0.0625
REAC REAC:R-HSA-5358346 Hedgehog ligand biogenesis 0.000360966010035746 65 32 4 0.125 0.0615384615384615
REAC REAC:R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 0.000363257063693575 66 32 4 0.125 0.0606060606060606
REAC REAC:R-HSA-69563 p53-Dependent G1 DNA Damage Response 0.000363257063693575 66 32 4 0.125 0.0606060606060606
REAC REAC:R-HSA-69580 p53-Dependent G1/S DNA damage checkpoint 0.000363257063693575 66 32 4 0.125 0.0606060606060606
REAC REAC:R-HSA-1169091 Activation of NF-kappaB in B cells 0.000372432684103388 67 32 4 0.125 0.0597014925373134
REAC REAC:R-HSA-5658442 Regulation of RAS by GAPs 0.000372432684103388 67 32 4 0.125 0.0597014925373134
REAC REAC:R-HSA-68867 Assembly of the pre-replicative complex 0.000375762712473819 68 32 4 0.125 0.0588235294117647
REAC REAC:R-HSA-69615 G1/S DNA Damage Checkpoints 0.000375762712473819 68 32 4 0.125 0.0588235294117647
REAC REAC:R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 0.000375762712473819 68 32 4 0.125 0.0588235294117647
REAC REAC:R-HSA-8948751 Regulation of PTEN stability and activity 0.000385600669174312 69 32 4 0.125 0.0579710144927536
REAC REAC:R-HSA-9683610 Maturation of nucleoprotein 0.000385600669174312 10 82 3 0.0365853658536585 0.3
REAC REAC:R-HSA-68949 Orc1 removal from chromatin 0.000424908461526749 71 32 4 0.125 0.0563380281690141
REAC REAC:R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 0.000459816627121019 73 32 4 0.125 0.0547945205479452
REAC REAC:R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 0.000459816627121019 73 32 4 0.125 0.0547945205479452
REAC REAC:R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 0.000470999856860883 74 32 4 0.125 0.0540540540540541
REAC REAC:R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 0.000470999856860883 74 32 4 0.125 0.0540540540540541
REAC REAC:R-HSA-1234174 Cellular response to hypoxia 0.000489385914932585 75 32 4 0.125 0.0533333333333333
REAC REAC:R-HSA-168249 Innate Immune System 0.000492600344028373 1073 109 25 0.229357798165138 0.0232991612301957
REAC REAC:R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 0.000501158203276182 76 32 4 0.125 0.0526315789473684
REAC REAC:R-HSA-5619084 ABC transporter disorders 0.000513239693570392 77 32 4 0.125 0.051948051948052
REAC REAC:R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 0.000513239693570392 77 32 4 0.125 0.051948051948052
REAC REAC:R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 0.000559851630939287 79 32 4 0.125 0.0506329113924051
REAC REAC:R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 0.000580328374575688 80 32 4 0.125 0.05
REAC REAC:R-HSA-9013694 Signaling by NOTCH4 0.000593558999689216 81 32 4 0.125 0.0493827160493827
REAC REAC:R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 0.000593558999689216 81 32 4 0.125 0.0493827160493827
REAC REAC:R-HSA-918233 TRAF3-dependent IRF activation pathway 0.00063549171285445 14 73 3 0.0410958904109589 0.214285714285714
REAC REAC:R-HSA-195253 Degradation of beta-catenin by the destruction complex 0.00063549171285445 83 32 4 0.125 0.0481927710843374
REAC REAC:R-HSA-69202 Cyclin E associated events during G1/S transition 0.00063549171285445 83 32 4 0.125 0.0481927710843374
REAC REAC:R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 0.000665089399829686 85 32 4 0.125 0.0470588235294118
REAC REAC:R-HSA-69002 DNA Replication Pre-Initiation 0.000665089399829686 85 32 4 0.125 0.0470588235294118
REAC REAC:R-HSA-5632684 Hedgehog 'on' state 0.000665089399829686 85 32 4 0.125 0.0470588235294118
REAC REAC:R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 0.000687862857400019 86 32 4 0.125 0.0465116279069767
REAC REAC:R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 0.000717338824477031 100 119 7 0.0588235294117647 0.07
REAC REAC:R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 0.000726501389676345 88 32 4 0.125 0.0454545454545455
REAC REAC:R-HSA-453276 Regulation of mitotic cell cycle 0.000726501389676345 88 32 4 0.125 0.0454545454545455
REAC REAC:R-HSA-5687128 MAPK6/MAPK4 signaling 0.000750545649356753 89 32 4 0.125 0.0449438202247191
REAC REAC:R-HSA-5689603 UCH proteinases 0.000775582074553077 92 132 7 0.053030303030303 0.0760869565217391
REAC REAC:R-HSA-69052 Switching of origins to a post-replicative state 0.000800102815275845 91 32 4 0.125 0.043956043956044
REAC REAC:R-HSA-4086400 PCP/CE pathway 0.000825622418915559 92 32 4 0.125 0.0434782608695652
REAC REAC:R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 0.00085900000413656 94 132 7 0.053030303030303 0.074468085106383
REAC REAC:R-HSA-8878159 Transcriptional regulation by RUNX3 0.000878160092829702 94 32 4 0.125 0.0425531914893617
REAC REAC:R-HSA-5607764 CLEC7A (Dectin-1) signaling 0.00098098732974384 97 32 4 0.125 0.0412371134020619
REAC REAC:R-HSA-5689880 Ub-specific processing proteases 0.000986141950184073 200 132 10 0.0757575757575758 0.05
REAC REAC:R-HSA-446652 Interleukin-1 family signaling 0.000988803472019586 138 123 8 0.0650406504065041 0.0579710144927536
REAC REAC:R-HSA-202424 Downstream TCR signaling 0.0009893186474765 98 32 4 0.125 0.0408163265306122
REAC REAC:R-HSA-9020702 Interleukin-1 signaling 0.00109988757497835 101 32 4 0.125 0.0396039603960396
REAC REAC:R-HSA-382556 ABC-family proteins mediated transport 0.0011741236617873 103 32 4 0.125 0.0388349514563107
REAC REAC:R-HSA-157118 Signaling by NOTCH 0.00134288523206582 197 32 5 0.15625 0.0253807106598985
REAC REAC:R-HSA-162906 HIV Infection 0.00149098428350257 226 44 6 0.136363636363636 0.0265486725663717
REAC REAC:R-HSA-5610787 Hedgehog 'off' state 0.00162518199765957 113 32 4 0.125 0.0353982300884956
REAC REAC:R-HSA-109581 Apoptosis 0.00168312689619542 174 38 5 0.131578947368421 0.028735632183908
REAC REAC:R-HSA-8851680 Butyrophilin (BTN) family interactions 0.00169728785005049 12 131 3 0.0229007633587786 0.25
REAC REAC:R-HSA-197264 Nicotinamide salvaging 0.00176974892383226 19 82 3 0.0365853658536585 0.157894736842105
REAC REAC:R-HSA-5357801 Programmed Cell Death 0.00176974892383226 177 38 5 0.131578947368421 0.0282485875706215
REAC REAC:R-HSA-202403 TCR signaling 0.00193035871847459 120 32 4 0.125 0.0333333333333333
REAC REAC:R-HSA-69239 Synthesis of DNA 0.00193035871847459 120 32 4 0.125 0.0333333333333333
REAC REAC:R-HSA-69306 DNA Replication 0.00244224738268015 128 32 4 0.125 0.03125
REAC REAC:R-HSA-5663205 Infectious disease 0.00251804812424023 815 46 11 0.239130434782609 0.0134969325153374
REAC REAC:R-HSA-69206 G1/S Transition 0.00261768288787373 131 32 4 0.125 0.0305343511450382
REAC REAC:R-HSA-5621481 C-type lectin receptors (CLRs) 0.00296096356031425 136 32 4 0.125 0.0294117647058824
REAC REAC:R-HSA-2871837 FCERI mediated NF-kB activation 0.00296096356031425 136 32 4 0.125 0.0294117647058824
REAC REAC:R-HSA-6807070 PTEN Regulation 0.00310054925502269 138 32 4 0.125 0.0289855072463768
REAC REAC:R-HSA-933541 TRAF6 mediated IRF7 activation 0.00334268173649963 27 73 3 0.0410958904109589 0.111111111111111
REAC REAC:R-HSA-3858494 Beta-catenin independent WNT signaling 0.00348207790742819 143 32 4 0.125 0.027972027972028
REAC REAC:R-HSA-453279 Mitotic G1 phase and G1/S transition 0.00392518224722825 148 32 4 0.125 0.027027027027027
REAC REAC:R-HSA-69481 G2/M Checkpoints 0.0039578262882108 149 32 4 0.125 0.0268456375838926
REAC REAC:R-HSA-5358351 Signaling by Hedgehog 0.0039578262882108 149 32 4 0.125 0.0268456375838926
REAC REAC:R-HSA-9683701 Translation of structural proteins 0.00500460916286797 28 82 3 0.0365853658536585 0.107142857142857
REAC REAC:R-HSA-69242 S Phase 0.00530923571023885 162 32 4 0.125 0.0246913580246914
REAC REAC:R-HSA-983705 Signaling by the B Cell Receptor (BCR) 0.00551007304768343 164 32 4 0.125 0.024390243902439
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.00596854326430304 446 134 14 0.104477611940299 0.031390134529148
REAC REAC:R-HSA-9010553 Regulation of expression of SLITs and ROBOs 0.00632366314806946 171 32 4 0.125 0.0233918128654971
REAC REAC:R-HSA-196807 Nicotinate metabolism 0.0064846294424063 31 82 3 0.0365853658536585 0.0967741935483871
REAC REAC:R-HSA-5619115 Disorders of transmembrane transporters 0.00649546450360858 173 32 4 0.125 0.023121387283237
REAC REAC:R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 0.00769814264717562 182 32 4 0.125 0.021978021978022
REAC REAC:R-HSA-5688426 Deubiquitination 0.00793844991877017 276 109 9 0.0825688073394495 0.0326086956521739
REAC REAC:R-HSA-2467813 Separation of Sister Chromatids 0.00853069559067798 188 32 4 0.125 0.0212765957446809
REAC REAC:R-HSA-201681 TCF dependent signaling in response to WNT 0.00962758397011028 196 32 4 0.125 0.0204081632653061
REAC REAC:R-HSA-69275 G2/M Transition 0.00962758397011028 196 32 4 0.125 0.0204081632653061
REAC REAC:R-HSA-453274 Mitotic G2-G2/M phases 0.00991384672328309 198 32 4 0.125 0.0202020202020202
REAC REAC:R-HSA-8878171 Transcriptional regulation by RUNX1 0.0101415409600335 200 32 4 0.125 0.02
REAC REAC:R-HSA-376176 Signaling by ROBO receptors 0.0131928416576687 217 32 4 0.125 0.0184331797235023
REAC REAC:R-HSA-68882 Mitotic Anaphase 0.015510414260037 228 32 4 0.125 0.0175438596491228
REAC REAC:R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers 0.0155369412288483 371 32 5 0.15625 0.0134770889487871
REAC REAC:R-HSA-2555396 Mitotic Metaphase and Anaphase 0.0155369412288483 229 32 4 0.125 0.0174672489082969
REAC REAC:R-HSA-8951664 Neddylation 0.0164058401269651 233 32 4 0.125 0.0171673819742489
REAC REAC:R-HSA-1257604 PIP3 activates AKT signaling 0.0205793016595344 249 32 4 0.125 0.0160642570281124
REAC REAC:R-HSA-9678108 SARS-CoV-1 Infection 0.0215088947483378 50 82 3 0.0365853658536585 0.06
REAC REAC:R-HSA-5673001 RAF/MAP kinase cascade 0.0248898675087239 264 32 4 0.125 0.0151515151515152
REAC REAC:R-HSA-5684996 MAPK1/MAPK3 signaling 0.02638260725955 269 32 4 0.125 0.0148698884758364
REAC REAC:R-HSA-69620 Cell Cycle Checkpoints 0.0268876185997386 271 32 4 0.125 0.014760147601476
REAC REAC:R-HSA-9607240 FLT3 Signaling 0.0291618739231082 278 32 4 0.125 0.0143884892086331
REAC REAC:R-HSA-9006925 Intracellular signaling by second messengers 0.032366356119758 289 32 4 0.125 0.013840830449827
REAC REAC:R-HSA-195721 Signaling by WNT 0.0329856944128261 292 32 4 0.125 0.0136986301369863
REAC REAC:R-HSA-5683057 MAPK family signaling cascades 0.0371909613736132 308 32 4 0.125 0.012987012987013
REAC REAC:R-HSA-71291 Metabolism of amino acids and derivatives 0.0394586499504906 368 110 9 0.0818181818181818 0.0244565217391304
REAC REAC:R-HSA-451927 Interleukin-2 family signaling 0.0482098013689547 44 134 3 0.0223880597014925 0.0681818181818182
REAC REAC:R-HSA-380108 Chemokine receptors bind chemokines 0.0489190731675207 57 104 3 0.0288461538461538 0.0526315789473684
TF TF:M09957 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN 1.53330152497827e-61 272 145 55 0.379310344827586 0.202205882352941
TF TF:M11685 Factor: IRF-8; motif: NCGAAACYGAAACYN 3.63647200893159e-58 1617 146 91 0.623287671232877 0.0562770562770563
TF TF:M07216 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT 1.92465009890457e-57 440 145 60 0.413793103448276 0.136363636363636
TF TF:M11664 Factor: IRF-2; motif: NGAAASYGAAAS 1.06918522027927e-56 1651 129 85 0.65891472868217 0.0514839491217444
TF TF:M08887 Factor: IRF; motif: NNGAAANTGAAANN 9.44299565788166e-52 1267 131 75 0.572519083969466 0.0591949486977111
TF TF:M08775_1 Factor: IRF-2; motif: NAANYGAAASYR; match class: 1 2.81305162252219e-48 2761 146 100 0.684931506849315 0.0362187613183629
TF TF:M11665 Factor: IRF-2; motif: NGAAASYGAAAS 3.56170651938878e-47 2396 146 94 0.643835616438356 0.0392320534223706
TF TF:M04020 Factor: IRF8; motif: NCGAAACCGAAACT 1.94537392100712e-45 992 129 64 0.496124031007752 0.0645161290322581
TF TF:M04788 Factor: IRF-1; motif: STTTCACTTTCNNT 2.04166511153255e-44 536 123 51 0.414634146341463 0.0951492537313433
TF TF:M11679 Factor: IRF-7; motif: NCGAAANCGAAANYN 2.98920338581901e-44 622 134 55 0.41044776119403 0.0884244372990354
TF TF:M04018 Factor: IRF7; motif: NCGAAARYGAAANT 2.22059835201716e-41 619 129 52 0.403100775193798 0.0840064620355412
TF TF:M11687 Factor: IRF-4; motif: NCGAAACCGAAACYN 5.49942270561746e-41 3595 146 103 0.705479452054795 0.0286509040333797
TF TF:M00453 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN 5.99901977945958e-41 3082 146 97 0.664383561643836 0.0314730694354315
TF TF:M11682 Factor: IRF-8; motif: NYGAAASYGAAACYN 7.02839170942139e-41 3795 146 105 0.719178082191781 0.0276679841897233
TF TF:M09629 Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN 1.12059735761434e-39 336 130 42 0.323076923076923 0.125
TF TF:M11686 Factor: IRF-4; motif: NYGAAASYGAAACYN 2.36192256249667e-39 3391 146 99 0.678082191780822 0.0291949277499263
TF TF:M11670 Factor: IRF-5; motif: NYGAAACCGAAACY 1.25137300216328e-38 871 109 52 0.477064220183486 0.0597014925373134
TF TF:M09956 Factor: IRF-1; motif: NAAANNGAAASTGAAASNRN 1.41189713813915e-38 317 145 42 0.289655172413793 0.132492113564669
TF TF:M04014 Factor: IRF3; motif: NNRRAANGGAAACCGAAACYR 7.58126942013359e-37 278 143 39 0.272727272727273 0.140287769784173
TF TF:M11677 Factor: IRF-3; motif: NGGAAACNGAAACCGAAACN 1.50183855062338e-36 470 145 46 0.317241379310345 0.0978723404255319
TF TF:M11685_1 Factor: IRF-8; motif: NCGAAACYGAAACYN; match class: 1 2.36390040268917e-36 118 108 28 0.259259259259259 0.23728813559322
TF TF:M11683 Factor: IRF-8; motif: NCGAAACCGAAACYN 4.01849759025388e-36 4690 146 109 0.746575342465753 0.0232409381663113
TF TF:M00772 Factor: IRF; motif: RRAANTGAAASYGNV 4.87746723533736e-36 1029 146 60 0.410958904109589 0.0583090379008746
TF TF:M11683_1 Factor: IRF-8; motif: NCGAAACCGAAACYN; match class: 1 6.72598336105981e-36 814 146 55 0.376712328767123 0.0675675675675676
TF TF:M09733 Factor: STAT2; motif: NRGAAANNGAAACTNA 3.49332473756516e-35 2842 146 88 0.602739726027397 0.0309641097818438
TF TF:M07045 Factor: IRF-1; motif: NNRAAANNGAAASN 9.8670284528488e-35 535 118 43 0.364406779661017 0.0803738317757009
TF TF:M04015 Factor: IRF-4; motif: NCGAAACCGAAACYA 2.04362795357071e-34 2038 111 66 0.594594594594595 0.0323846908734053
TF TF:M10080 Factor: STAT2; motif: RRGRAANNGAAACTGAAAN 2.62940474987474e-34 356 122 38 0.311475409836066 0.106741573033708
TF TF:M11684 Factor: IRF-8; motif: NYGAAACYGAAACTN 1.35555229091439e-33 4664 146 106 0.726027397260274 0.0227272727272727
TF TF:M11671 Factor: IRF-5; motif: NCGAAACCGAAACY 1.72890325862691e-33 389 127 39 0.307086614173228 0.10025706940874
TF TF:M08887_1 Factor: IRF; motif: NNGAAANTGAAANN; match class: 1 2.30979600122213e-33 73 146 25 0.171232876712329 0.342465753424658
TF TF:M09733_1 Factor: STAT2; motif: NRGAAANNGAAACTNA; match class: 1 3.20568470223255e-33 367 146 40 0.273972602739726 0.108991825613079
TF TF:M11684_1 Factor: IRF-8; motif: NYGAAACYGAAACTN; match class: 1 2.18105851976286e-32 832 108 46 0.425925925925926 0.0552884615384615
TF TF:M11687_1 Factor: IRF-4; motif: NCGAAACCGAAACYN; match class: 1 5.92684670404483e-32 474 108 38 0.351851851851852 0.080168776371308
TF TF:M11664_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 7.22213314824351e-32 140 146 29 0.198630136986301 0.207142857142857
TF TF:M11682_1 Factor: IRF-8; motif: NYGAAASYGAAACYN; match class: 1 4.4234354503201e-31 543 108 39 0.361111111111111 0.0718232044198895
TF TF:M08775 Factor: IRF-2; motif: NAANYGAAASYR 2.66375590980029e-30 8370 134 122 0.91044776119403 0.0145758661887694
TF TF:M11665_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 5.0688598439044e-30 246 146 33 0.226027397260274 0.134146341463415
TF TF:M00453_1 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN; match class: 1 5.49699824490695e-29 332 108 32 0.296296296296296 0.0963855421686747
TF TF:M11686_1 Factor: IRF-4; motif: NYGAAASYGAAACYN; match class: 1 1.11162265636834e-28 452 108 35 0.324074074074074 0.0774336283185841
TF TF:M07323 Factor: IRF-4; motif: KRAAMNGAAANYN 8.13547791089915e-28 938 108 44 0.407407407407407 0.046908315565032
TF TF:M00972 Factor: IRF; motif: RAAANTGAAAN 1.1137189080003e-27 1979 146 68 0.465753424657534 0.0343607882769075
TF TF:M04015_1 Factor: IRF-4; motif: NCGAAACCGAAACYA; match class: 1 1.82855526495651e-27 158 143 27 0.188811188811189 0.170886075949367
TF TF:M11676 Factor: IRF-3; motif: NGGAAANGGAAASNGAAACN 3.37572920713552e-26 562 145 40 0.275862068965517 0.0711743772241993
TF TF:M00258 Factor: ISGF-3; motif: CAGTTTCWCTTTYCC 1.68908647860744e-25 823 108 40 0.37037037037037 0.0486026731470231
TF TF:M00699 Factor: ICSBP; motif: RAARTGAAACTG 6.6336604665989e-25 1184 123 48 0.390243902439024 0.0405405405405405
TF TF:M04020_1 Factor: IRF8; motif: NCGAAACCGAAACT; match class: 1 1.6290076216881e-23 45 108 16 0.148148148148148 0.355555555555556
TF TF:M11681 Factor: IRF-9; motif: NCGAAACYGAAACYN 2.15472887858654e-23 97 143 21 0.146853146853147 0.216494845360825
TF TF:M11680 Factor: IRF-9; motif: NYGAAACYGAAACYN 2.15472887858654e-23 128 108 21 0.194444444444444 0.1640625
TF TF:M04016 Factor: IRF5; motif: CCGAAACCGAAACY 4.57944071695391e-22 314 127 28 0.220472440944882 0.089171974522293
TF TF:M11672 Factor: IRF-5; motif: NCGAAACCGAAACY 2.53679683821679e-21 120 143 21 0.146853146853147 0.175
TF TF:M00699_1 Factor: ICSBP; motif: RAARTGAAACTG; match class: 1 3.50802710538553e-21 47 108 15 0.138888888888889 0.319148936170213
TF TF:M09958 Factor: IRF-3; motif: RAAARGGAAANNGAAASNGA 3.50802710538553e-21 589 126 34 0.26984126984127 0.0577249575551783
TF TF:M11670_1 Factor: IRF-5; motif: NYGAAACCGAAACY; match class: 1 4.78624258810517e-19 36 108 13 0.12037037037037 0.361111111111111
TF TF:M00258_1 Factor: ISGF-3; motif: CAGTTTCWCTTTYCC; match class: 1 3.6919152632429e-18 30 108 12 0.111111111111111 0.4
TF TF:M00972_1 Factor: IRF; motif: RAAANTGAAAN; match class: 1 7.91401879307426e-18 205 90 19 0.211111111111111 0.0926829268292683
TF TF:M11673 Factor: IRF-5; motif: NCGAAACCGAAACY 3.94291511664241e-16 57 143 14 0.0979020979020979 0.245614035087719
TF TF:M00772_1 Factor: IRF; motif: RRAANTGAAASYGNV; match class: 1 4.29654490847689e-16 57 108 13 0.12037037037037 0.228070175438596
TF TF:M11679_1 Factor: IRF-7; motif: NCGAAANCGAAANYN; match class: 1 1.72739684421895e-15 23 107 10 0.0934579439252336 0.434782608695652
TF TF:M09745 Factor: HELIOS; motif: RNARRRGGAASTGARAN 3.26781221409553e-15 3582 92 53 0.576086956521739 0.0147962032384143
TF TF:M07045_1 Factor: IRF-1; motif: NNRAAANNGAAASN; match class: 1 3.40322996001872e-15 19 146 10 0.0684931506849315 0.526315789473684
TF TF:M00063 Factor: IRF-2; motif: GAAAAGYGAAASY 3.5790111291687e-14 685 146 31 0.212328767123288 0.0452554744525547
TF TF:M01882 Factor: IRF-2; motif: NNRAAAGTGAAASNNA 3.70844073309313e-14 258 146 21 0.143835616438356 0.0813953488372093
TF TF:M04788_1 Factor: IRF-1; motif: STTTCACTTTCNNT; match class: 1 1.23618579775761e-13 17 146 9 0.0616438356164384 0.529411764705882
TF TF:M07216_1 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT; match class: 1 1.90332981448712e-12 35 131 10 0.0763358778625954 0.285714285714286
TF TF:M10080_1 Factor: STAT2; motif: RRGRAANNGAAACTGAAAN; match class: 1 3.9159649562711e-12 11 108 7 0.0648148148148148 0.636363636363636
TF TF:M11678 Factor: IRF-7; motif: NNGAAAGTGAAANTR 8.79629383201607e-12 179 91 14 0.153846153846154 0.0782122905027933
TF TF:M00062 Factor: IRF-1; motif: SAAAAGYGAAACC 1.14228691476898e-11 576 134 25 0.186567164179104 0.0434027777777778
TF TF:M09745_1 Factor: HELIOS; motif: RNARRRGGAASTGARAN; match class: 1 3.61383899163486e-10 495 55 15 0.272727272727273 0.0303030303030303
TF TF:M04018_1 Factor: IRF7; motif: NCGAAARYGAAANT; match class: 1 4.64926239319834e-10 24 81 7 0.0864197530864197 0.291666666666667
TF TF:M09629_1 Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN; match class: 1 2.45256891764099e-09 29 145 8 0.0551724137931034 0.275862068965517
TF TF:M01279 Factor: IRF-3; motif: NBNBTTTCSCTTT 2.79740961882445e-09 1647 145 39 0.268965517241379 0.0236794171220401
TF TF:M09957_1 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN; match class: 1 3.47305977251921e-09 22 119 7 0.0588235294117647 0.318181818181818
TF TF:M11676_1 Factor: IRF-3; motif: NGGAAANGGAAASNGAAACN; match class: 1 3.90443667628988e-09 41 106 8 0.0754716981132075 0.195121951219512
TF TF:M04017 Factor: IRF5; motif: NACCGAAACYA 4.07116543983063e-09 195 107 13 0.121495327102804 0.0666666666666667
TF TF:M07323_1 Factor: IRF-4; motif: KRAAMNGAAANYN; match class: 1 9.37854021316073e-09 39 125 8 0.064 0.205128205128205
TF TF:M11671_1 Factor: IRF-5; motif: NCGAAACCGAAACY; match class: 1 1.10274875691362e-08 14 120 6 0.05 0.428571428571429
TF TF:M03793 Factor: IRF-7; motif: AARGGAAANNGAA 1.31172511978481e-08 1987 145 42 0.289655172413793 0.0211373930548566
TF TF:M03916 Factor: PRDM1; motif: NRAAAGTGAAAGTNN 2.11661649633102e-08 948 145 28 0.193103448275862 0.029535864978903
TF TF:M03916_1 Factor: PRDM1; motif: NRAAAGTGAAAGTNN; match class: 1 4.94737158940319e-08 50 119 8 0.0672268907563025 0.16
TF TF:M09649 Factor: Blimp-1; motif: RAAAGTGAAAGTNN 5.93666918535841e-08 300 145 16 0.110344827586207 0.0533333333333333
TF TF:M11680_1 Factor: IRF-9; motif: NYGAAACYGAAACYN; match class: 1 6.82198922469853e-08 4 108 4 0.037037037037037 1
TF TF:M10040_1 Factor: Blimp-1; motif: RAAAGNGAAAGTNN; match class: 1 1.14502305598531e-07 12 91 5 0.0549450549450549 0.416666666666667
TF TF:M01882_1 Factor: IRF-2; motif: NNRAAAGTGAAASNNA; match class: 1 2.2571596888566e-07 4 146 4 0.0273972602739726 1
TF TF:M01066 Factor: Blimp-1; motif: NRGRAAGKGAAAGKRN 3.5240055907953e-07 411 138 17 0.123188405797101 0.0413625304136253
TF TF:M10040 Factor: Blimp-1; motif: RAAAGNGAAAGTNN 9.61940384584436e-07 366 145 16 0.110344827586207 0.0437158469945355
TF TF:M07121 Factor: Blimp-1; motif: NRAAAGTGAAAGTNN 3.39443840327358e-06 401 145 16 0.110344827586207 0.0399002493765586
TF TF:M04016_1 Factor: IRF5; motif: CCGAAACCGAAACY; match class: 1 4.3751828963105e-06 8 108 4 0.037037037037037 0.5
TF TF:M07314 Factor: Blimp-1; motif: RGRAAGNGAAAG 4.73890007320213e-06 1460 145 31 0.213793103448276 0.0212328767123288
TF TF:M01066_1 Factor: Blimp-1; motif: NRGRAAGKGAAAGKRN; match class: 1 6.22989429200818e-06 11 81 4 0.0493827160493827 0.363636363636364
TF TF:M07121_1 Factor: Blimp-1; motif: NRAAAGTGAAAGTNN; match class: 1 9.86972435751107e-06 11 91 4 0.043956043956044 0.363636363636364
TF TF:M01665 Factor: IRF-8; motif: AGTTTCW 1.08230885796507e-05 4771 108 51 0.472222222222222 0.0106895828966674
TF TF:M09956_1 Factor: IRF-1; motif: NAAANNGAAASTGAAASNRN; match class: 1 1.60359181519139e-05 23 119 5 0.0420168067226891 0.217391304347826
TF TF:M11677_1 Factor: IRF-3; motif: NGGAAACNGAAACCGAAACN; match class: 1 1.7984764561362e-05 26 107 5 0.0467289719626168 0.192307692307692
TF TF:M08295_1 Factor: FOXO1A:Elf-1; motif: NAGAAAACCGAANM; match class: 1 3.25528322646584e-05 4997 121 56 0.462809917355372 0.0112067240344207
TF TF:M07314_1 Factor: Blimp-1; motif: RGRAAGNGAAAG; match class: 1 3.99567829647086e-05 118 119 8 0.0672268907563025 0.0677966101694915
TF TF:M10046_1 Factor: c-Rel; motif: NRNRGGGRAATKCCA; match class: 1 6.35909973657941e-05 734 67 13 0.194029850746269 0.0177111716621253
TF TF:M01224 Factor: P50:RELA-P65; motif: GGANTTYCCCWN 7.43171160770529e-05 2329 96 29 0.302083333333333 0.0124516960068699
TF TF:M00208_1 Factor: NF-kappaB; motif: NGGGACTTTCCA; match class: 1 0.000103747435615678 604 84 13 0.154761904761905 0.021523178807947
TF TF:M09933_1 Factor: FOXP1; motif: TNTGTTTMY; match class: 1 0.000229778457250175 634 86 13 0.151162790697674 0.0205047318611987
TF TF:M11675 Factor: IRF-3; motif: KCNGTTTCSNSGAAACCGAAACN 0.000266138731529282 4655 133 55 0.413533834586466 0.0118152524167562
TF TF:M04903_1 Factor: HNF-4alpha; motif: AGTCCAAR; match class: 1 0.000521289751562005 1534 41 13 0.317073170731707 0.00847457627118644
TF TF:M01665_1 Factor: IRF-8; motif: AGTTTCW; match class: 1 0.000568084826805089 721 22 7 0.318181818181818 0.00970873786407767
TF TF:M06507 Factor: ZFP90; motif: NGGGASTTTAKA 0.000568084826805089 40 65 4 0.0615384615384615 0.1
TF TF:M11988_1 Factor: NFATc3; motif: NTTTCCRYGGAAAN; match class: 1 0.000579418907957646 6648 123 65 0.528455284552846 0.00977737665463297
TF TF:M03545_1 Factor: c-Rel; motif: NGGGAATYTCCN; match class: 1 0.000612056294406515 1011 79 15 0.189873417721519 0.0148367952522255
TF TF:M00747_1 Factor: IRF-1; motif: TTCACTT; match class: 1 0.000667449419240514 933 66 13 0.196969696969697 0.0139335476956056
TF TF:M09649_1 Factor: Blimp-1; motif: RAAAGTGAAAGTNN; match class: 1 0.000678503147348636 10 91 3 0.032967032967033 0.3
TF TF:M00054 Factor: NF-kappaB; motif: GGGAMTTYCC 0.000702309023124016 2444 92 27 0.293478260869565 0.0110474631751228
TF TF:M08295 Factor: FOXO1A:Elf-1; motif: NAGAAAACCGAANM 0.0007074331189647 11711 122 95 0.778688524590164 0.00811203142344804
TF TF:M11674 Factor: IRF-3; motif: GCNGTTTCCWGGAAACNGAAAC 0.00072645051950902 4623 76 35 0.460526315789474 0.00757084144494917
TF TF:M00208 Factor: NF-kappaB; motif: NGGGACTTTCCA 0.00072645051950902 3757 91 35 0.384615384615385 0.00931594357199893
TF TF:M00194_1 Factor: NF-kappaB; motif: NGGGGAMTTTCCNN; match class: 1 0.000745152825575675 385 134 12 0.0895522388059701 0.0311688311688312
TF TF:M04014_1 Factor: IRF3; motif: NNRRAANGGAAACCGAAACYR; match class: 1 0.000755742047088729 9 108 3 0.0277777777777778 0.333333333333333
TF TF:M11378 Factor: ESE-1; motif: ACMAGGAAGTANNNNNNNWWAWW 0.00109316122897075 3049 61 23 0.377049180327869 0.00754345687110528
TF TF:M07038_1 Factor: DBP; motif: TTRCATAANN; match class: 1 0.00109316122897075 772 83 13 0.156626506024096 0.016839378238342
TF TF:M03793_1 Factor: IRF-7; motif: AARGGAAANNGAA; match class: 1 0.00164602125989189 138 126 7 0.0555555555555556 0.0507246376811594
TF TF:M11988 Factor: NFATc3; motif: NTTTCCRYGGAAAN 0.00170506290402345 7175 123 67 0.544715447154472 0.00933797909407666
TF TF:M12067 Factor: ZNF32; motif: NYGTAACNYGAYACC 0.0017619475485749 164 73 6 0.0821917808219178 0.0365853658536585
TF TF:M03875 Factor: IRF-5; motif: KTTTCGCTTTCMT 0.00180456862468073 100 120 6 0.05 0.06
TF TF:M05989 Factor: ZNF275; motif: KGGGMCWTTAGA 0.00222403092717993 36 37 3 0.0810810810810811 0.0833333333333333
TF TF:M03557_1 Factor: P50; motif: GGRRANTCCCNN; match class: 1 0.00233294999905919 1292 141 23 0.163120567375887 0.0178018575851393
TF TF:M00155 Factor: ARP-1; motif: TGARCCYTTGAMCCCW 0.0023485208864414 5581 48 27 0.5625 0.0048378426805232
TF TF:M08632 Factor: TEF-3:Dlx-2; motif: RMATWCYNNNYAATTA 0.0024364735128573 600 99 12 0.121212121212121 0.02
TF TF:M02015 Factor: HNF-3gamma; motif: TGTTTRYT 0.0024578597974469 2809 87 27 0.310344827586207 0.00961196155215379
TF TF:M11453 Factor: ELFR; motif: AAMCAGGAAGTR 0.00251905792953116 488 69 9 0.130434782608696 0.0184426229508197
TF TF:M01884_1 Factor: IRF-7; motif: AAGWGAA; match class: 1 0.00252921507860997 4556 126 49 0.388888888888889 0.0107550482879719
TF TF:M11817_1 Factor: T3R-beta; motif: NRRGGTCRTGACCYYN; match class: 1 0.00252921507860997 1566 88 19 0.215909090909091 0.0121328224776501
TF TF:M09818 Factor: PRDM1; motif: TCACTTTCWC 0.00256396556127735 1087 146 21 0.143835616438356 0.0193192272309108
TF TF:M10526_1 Factor: Blimp-1; motif: RRGNGAAAGNRANNN; match class: 1 0.00256396556127735 286 145 10 0.0689655172413793 0.034965034965035
TF TF:M00054_1 Factor: NF-kappaB; motif: GGGAMTTYCC; match class: 1 0.00256396556127735 712 72 11 0.152777777777778 0.0154494382022472
TF TF:M00158 Factor: COUP-TF,; motif: TGAMCTTTGMMCYT 0.00267834082245682 2215 145 33 0.227586206896552 0.0148984198645598
TF TF:M09589 Factor: AR; motif: NGNACANNNTGTTCYNN 0.0027351233032104 5130 82 38 0.463414634146341 0.00740740740740741
TF TF:M00687 Factor: alpha-CP1; motif: CAGCCAATGAG 0.00284552674100381 2326 67 20 0.298507462686567 0.00859845227858985
TF TF:M01279_1 Factor: IRF-3; motif: NBNBTTTCSCTTT; match class: 1 0.00305602564916734 101 82 5 0.0609756097560976 0.0495049504950495
TF TF:M10526 Factor: Blimp-1; motif: RRGNGAAAGNRANNN 0.00333881642524855 2327 146 34 0.232876712328767 0.0146110872367856
TF TF:M00774_1 Factor: NF-kappaB; motif: NGGGANTTYCCMNNNN; match class: 1 0.00341446083721066 192 72 6 0.0833333333333333 0.03125
TF TF:M00747 Factor: IRF-1; motif: TTCACTT 0.00357676942649217 5208 134 56 0.417910447761194 0.010752688172043
TF TF:M01883_1 Factor: IRF-4; motif: GAAARTA; match class: 1 0.00364043455744575 2948 132 37 0.28030303030303 0.012550881953867
TF TF:M09899 Factor: ehf; motif: NNANSAGGAAGTNNN 0.00364192759219709 457 136 12 0.0882352941176471 0.0262582056892779
TF TF:M02377 Factor: ESR2; motif: NNRGGTCANNNTGMCCTN 0.00423754342398739 3517 89 31 0.348314606741573 0.0088143303952232
TF TF:M03563_1 Factor: RelA-p65; motif: GGGANTTTCCNN; match class: 1 0.00468934962852901 876 135 17 0.125925925925926 0.0194063926940639
TF TF:M11383 Factor: ESE-1; motif: ACCAGGAAGTANNNNNNNAAWAA 0.00496840774050721 3886 61 25 0.409836065573771 0.00643335048893464
TF TF:M12334 Factor: ZBTB20; motif: NNAAYGTATRKN 0.00575167969601165 1214 110 18 0.163636363636364 0.014827018121911
TF TF:M03557 Factor: P50; motif: GGRRANTCCCNN 0.00582585799471567 4967 61 29 0.475409836065574 0.00583853432655526
TF TF:M02015_1 Factor: HNF-3gamma; motif: TGTTTRYT; match class: 1 0.00613250217336183 742 77 11 0.142857142857143 0.0148247978436658
TF TF:M00148_1 Factor: SRY; motif: AAACWAM; match class: 1 0.00620691183808241 4397 94 37 0.393617021276596 0.00841482829201728
TF TF:M01223_1 Factor: P50:P50; motif: NRGGGAMTNCCCN; match class: 1 0.00638327676371893 161 33 4 0.121212121212121 0.0248447204968944
TF TF:M00791_1 Factor: HNF3; motif: NWRARYAAAYANN; match class: 1 0.00652522436105432 749 77 11 0.142857142857143 0.0146862483311081
TF TF:M02108 Factor: CSX; motif: NNCACTTGNRN 0.00693796956187684 7061 65 38 0.584615384615385 0.00538167398385498
TF TF:M11378_1 Factor: ESE-1; motif: ACMAGGAAGTANNNNNNNWWAWW; match class: 1 0.00720822476831119 321 72 7 0.0972222222222222 0.0218068535825545
TF TF:M03547 Factor: ER-alpha; motif: TGACCYN 0.00720822476831119 4712 108 43 0.398148148148148 0.00912563667232598
TF TF:M09959_1 Factor: IRF-4; motif: NAANGRGGAASTGAAASN; match class: 1 0.00751776732769323 395 42 6 0.142857142857143 0.0151898734177215
TF TF:M07204 Factor: AR; motif: ARGAACANNNTGTNC 0.00753075608215408 4906 54 26 0.481481481481481 0.00529963310232368
TF TF:M00447_1 Factor: AR; motif: AGWACATNWTGTTCT; match class: 1 0.00787849252065317 854 48 9 0.1875 0.0105386416861827
TF TF:M00052_1 Factor: NF-kappaB; motif: GGGRATTTCC; match class: 1 0.00791559550815726 94 111 5 0.045045045045045 0.0531914893617021
TF TF:M04706 Factor: RelA; motif: GGGRAWTYC 0.00805399066170269 2278 138 31 0.22463768115942 0.0136084284460053
TF TF:M00791 Factor: HNF3; motif: NWRARYAAAYANN 0.00810190341889978 2732 132 34 0.257575757575758 0.0124450951683748
TF TF:M00289_1 Factor: HFH3; motif: KNNTRTTTRTTTA; match class: 1 0.00810190341889978 817 111 14 0.126126126126126 0.0171358629130967
TF TF:M09902_1 Factor: ESE-1; motif: NNANVAGGAAGTNN; match class: 1 0.00815258580177938 306 55 6 0.109090909090909 0.0196078431372549
TF TF:M10170 Factor: ZNF85; motif: ANAGAARWCTGMWGKAATCT 0.00815258580177938 181 13 3 0.230769230769231 0.0165745856353591
TF TF:M10587 Factor: Barx-2; motif: NWWAAYMATTAN 0.0086340608935576 1776 130 25 0.192307692307692 0.0140765765765766
TF TF:M03882_1 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC; match class: 1 0.00869924507927616 714 35 7 0.2 0.00980392156862745
TF TF:M00638 Factor: HNF4alpha; motif: VTGAACTTTGMMB 0.00944017000588243 2814 145 37 0.255172413793103 0.0131485429992893
TF TF:M04849_1 Factor: RelA-p65; motif: AAASTCCC; match class: 1 0.00960507908929444 1170 62 12 0.193548387096774 0.0102564102564103
TF TF:M09958_1 Factor: IRF-3; motif: RAAARGGAAANNGAAASNGA; match class: 1 0.0097369491631238 93 119 5 0.0420168067226891 0.0537634408602151
TF TF:M01172_1 Factor: PU.1; motif: NNNNYYYACTTCCTCTTTY; match class: 1 0.00978516187255899 580 72 9 0.125 0.0155172413793103
TF TF:M11458 Factor: nerf; motif: AANCMGGAAGTR 0.0102537873677598 505 50 7 0.14 0.0138613861386139
TF TF:M08719 Factor: HOXB2:Sox-20; motif: ACAATRSNNNNNNNATYA 0.0109401133162073 1849 99 21 0.212121212121212 0.0113574905354246
TF TF:M06132 Factor: ZNF823; motif: NYYACCAGCCCT 0.0109401133162073 55 114 4 0.0350877192982456 0.0727272727272727
TF TF:M09959 Factor: IRF-4; motif: NAANGRGGAASTGAAASN 0.011317005509268 3386 42 17 0.404761904761905 0.00502067336089781
TF TF:M09930_1 Factor: foxm1; motif: TGTTTRCTYWNN; match class: 1 0.0116989754889504 1545 86 17 0.197674418604651 0.0110032362459547
TF TF:M03882 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC 0.011925992293293 4474 42 20 0.476190476190476 0.00447027268663388
TF TF:M00340_1 Factor: c-Ets; motif: KRCAGGAARTRNKT; match class: 1 0.0120738898363795 906 118 15 0.127118644067797 0.0165562913907285
TF TF:M04802 Factor: c-Fos; motif: ACTCACCA 0.0127983179507462 7386 90 50 0.555555555555556 0.00676956404007582
TF TF:M03855 Factor: Tbx5:csx; motif: YMTYCTSWCACYTGN 0.012868333840455 92 72 4 0.0555555555555556 0.0434782608695652
TF TF:M07221_1 Factor: NF-kappaB1; motif: KGGRNTTTCCM; match class: 1 0.013280483831198 163 114 6 0.0526315789473684 0.0368098159509202
TF TF:M00205_1 Factor: GR; motif: GGTACAANNTGTYCTK; match class: 1 0.0134684007108864 1482 52 12 0.230769230769231 0.00809716599190283
TF TF:M02114 Factor: pitx2; motif: NNTAAWCCCA 0.0134684007108864 4685 142 52 0.366197183098592 0.0110992529348986
TF TF:M07056 Factor: Pitx2; motif: WNTAAWCCCA 0.0134684007108864 4685 142 52 0.366197183098592 0.0110992529348986
TF TF:M05946_1 Factor: PRDM16; motif: KGGTCATRACCM; match class: 1 0.0141546592249623 2282 89 22 0.247191011235955 0.00964066608238387
TF TF:M01223 Factor: P50:P50; motif: NRGGGAMTNCCCN 0.0147704593637117 1283 44 10 0.227272727272727 0.00779423226812159
TF TF:M00794 Factor: TTF-1; motif: NNNNCAAGNRNN 0.0147927436659836 4679 136 50 0.367647058823529 0.0106860440265014
TF TF:M04249_1 Factor: FOXJ3; motif: RTAAACAA; match class: 1 0.014951101860517 603 107 11 0.102803738317757 0.0182421227197347
TF TF:M10094_1 Factor: RelA-p65; motif: NWGGGRATTTCCMN; match class: 1 0.0150747539270212 242 111 7 0.0630630630630631 0.0289256198347107
TF TF:M07254 Factor: Foxc1; motif: TTVYTTTNW 0.0150747539270212 7741 106 59 0.556603773584906 0.00762175429531068
TF TF:M04681_1 Factor: JunD; motif: RTGACGTCA; match class: 1 0.0150943470849018 1726 13 6 0.461538461538462 0.00347624565469293
TF TF:M07322_1 Factor: HSF4; motif: CTGCMRN; match class: 1 0.0150943470849018 11797 15 15 1 0.00127150970585742
TF TF:M03849_1 Factor: Sox-4; motif: AACAAA; match class: 1 0.0153068252379988 9090 139 84 0.60431654676259 0.00924092409240924
TF TF:M00346 Factor: GATA-1; motif: NCWGATAACA 0.0153380801325016 4376 53 23 0.433962264150943 0.00525594149908592
TF TF:M00641 Factor: HSF; motif: TTCCMGARGYTTC 0.0153380801325016 3599 123 38 0.308943089430894 0.0105584884690192
TF TF:M11985 Factor: NFATc2; motif: TTTTCCATGGAAAA 0.0154874422143126 5845 90 42 0.466666666666667 0.00718562874251497
TF TF:M07124 Factor: AML3; motif: KNKNTYTGTGGTTTK 0.0164553296091204 1440 104 18 0.173076923076923 0.0125
TF TF:M00380 Factor: Pax-4; motif: RAAAAWTANNNNNNNNNNNNNNNYCACNCC 0.0165625085624533 852 78 11 0.141025641025641 0.0129107981220657
TF TF:M11571 Factor: HNF-3alpha; motif: YTRWGTMAATATTTRCWYWN 0.0174564487021054 4307 105 38 0.361904761904762 0.00882284652890643
TF TF:M03865 Factor: Blimp-1; motif: NRGRAAGKGAAAGK 0.0174564487021054 1048 142 18 0.126760563380282 0.017175572519084
TF TF:M10004 Factor: NF-kappaB2; motif: GGGRAANYCCC 0.0174932733527739 1073 94 14 0.148936170212766 0.0130475302889096
TF TF:M11983 Factor: NFATc2; motif: NTTTCCGCGGAAAN 0.0180904541930276 8048 29 21 0.724137931034483 0.00260934393638171
TF TF:M00513 Factor: ATF3; motif: CBCTGACGTCANCS 0.0185337707242241 6386 119 56 0.470588235294118 0.00876918258690886
TF TF:M08216 Factor: Elk-1:FOXI1; motif: ACCGGAAGTRTMAACAN 0.0187613253581453 7126 72 40 0.555555555555556 0.00561324726354196
TF TF:M11445 Factor: Elf-1; motif: NANCAGGAAGTR 0.0191479734355508 1689 55 13 0.236363636363636 0.00769686204854944
TF TF:M09941_1 Factor: GR; motif: RGNACANMNTGTNCY; match class: 1 0.0197783906921362 2046 52 14 0.269230769230769 0.00684261974584555
TF TF:M00641_1 Factor: HSF; motif: TTCCMGARGYTTC; match class: 1 0.0199694463880189 387 54 6 0.111111111111111 0.0155038759689922
TF TF:M02014 Factor: HNF-3beta; motif: NTRTTTRYT 0.0202954073239983 2650 80 22 0.275 0.00830188679245283
TF TF:M00052 Factor: NF-kappaB; motif: GGGRATTTCC 0.0204500655958214 1874 118 23 0.194915254237288 0.012273212379936
TF TF:M00457_1 Factor: STAT5A; motif: NAWTTCYNGGAANYN; match class: 1 0.0210042761162777 1589 147 24 0.163265306122449 0.0151038388923851
TF TF:M11290_1 Factor: ATF-3; motif: NATGATGTCATN; match class: 1 0.0211560906598052 1872 13 6 0.461538461538462 0.00320512820512821
TF TF:M09902 Factor: ESE-1; motif: NNANVAGGAAGTNN 0.0212707595425016 3200 55 19 0.345454545454545 0.0059375
TF TF:M07405_1 Factor: SREBP-1; motif: RTCACCCCAY; match class: 1 0.0212829743456657 1516 47 11 0.234042553191489 0.00725593667546174
TF TF:M09668 Factor: RelA-p65; motif: GGGRNTTTCCM 0.0219465521781444 3576 73 25 0.342465753424658 0.0069910514541387
TF TF:M00194 Factor: NF-kappaB; motif: NGGGGAMTTTCCNN 0.0219465521781444 2412 88 22 0.25 0.00912106135986733
TF TF:M01884 Factor: IRF-7; motif: AAGWGAA 0.0219465521781444 10868 127 88 0.692913385826772 0.00809716599190283
TF TF:M03563 Factor: RelA-p65; motif: GGGANTTTCCNN 0.02228100829182 4643 61 26 0.426229508196721 0.0055998276976093
TF TF:M00809_1 Factor: FOX; motif: KWTTGTTTRTTTW; match class: 1 0.02228100829182 1054 77 12 0.155844155844156 0.0113851992409867
TF TF:M00621 Factor: C/EBPdelta; motif: MATTKCNTMAYY 0.0225162610536712 3888 94 32 0.340425531914894 0.00823045267489712
TF TF:M07419 Factor: FOXP3; motif: NNNVAAACANWD 0.023753104833444 6311 96 46 0.479166666666667 0.00728886071937886
TF TF:M04144 Factor: TEAD3; motif: RCATTCCW 0.023753104833444 1211 8 4 0.5 0.00330305532617671
TF TF:M08510 Factor: TEF-3:Fli-1; motif: ACCGGAAATGCC 0.0241290946633588 7360 147 74 0.503401360544218 0.010054347826087
TF TF:M03865_1 Factor: Blimp-1; motif: NRGRAAGKGAAAGK; match class: 1 0.0241290946633588 45 81 3 0.037037037037037 0.0666666666666667
TF TF:M04317 Factor: EN1; motif: TAATTRSNYAATTA 0.0241290946633588 2735 84 23 0.273809523809524 0.00840950639853748
TF TF:M00774 Factor: NF-kappaB; motif: NGGGANTTYCCMNNNN 0.0241666390691566 1818 73 16 0.219178082191781 0.0088008800880088
TF TF:M04054_1 Factor: NF-kappaB; motif: AGGGGAWTCCCCT; match class: 1 0.0245895974304841 1295 32 8 0.25 0.00617760617760618
TF TF:M00447 Factor: AR; motif: AGWACATNWTGTTCT 0.025346099256715 4183 54 22 0.407407407407407 0.00525938321778628
TF TF:M03991 Factor: SPDEF; motif: AMCCGGATGTN 0.025346099256715 66 128 4 0.03125 0.0606060606060606
TF TF:M07221 Factor: NF-kappaB1; motif: KGGRNTTTCCM 0.02550604020779 2417 118 27 0.228813559322034 0.0111708729830368
TF TF:M07229 Factor: STAT3; motif: NTTCYKGGAAN 0.0256173498773052 3717 87 29 0.333333333333333 0.00780199085283831
TF TF:M10023 Factor: p53; motif: NGRCATGYCCAGRCATGYCY 0.0256173498773052 2746 10 6 0.6 0.0021849963583394
TF TF:M07341 Factor: TORC2; motif: TGGGCTKKD 0.0258900998259198 4887 5 5 1 0.0010231225700839
TF TF:M11675_1 Factor: IRF-3; motif: KCNGTTTCSNSGAAACCGAAACN; match class: 1 0.026653503699674 1848 53 13 0.245283018867925 0.00703463203463203
TF TF:M12286 Factor: ZNF647; motif: NYAGGCCYAC 0.026653503699674 6231 48 26 0.541666666666667 0.00417268496228535
TF TF:M01996 Factor: AR; motif: GNNCNNNNTGTTCTN 0.0270881865113834 3085 54 18 0.333333333333333 0.00583468395461912
TF TF:M04731 Factor: Blimp-1; motif: NACTTTCAC 0.0277501016247013 3997 147 46 0.312925170068027 0.0115086314736052
TF TF:M11985_1 Factor: NFATc2; motif: TTTTCCATGGAAAA; match class: 1 0.0281926592568749 4518 90 34 0.377777777777778 0.00752545374059318
TF TF:M11807 Factor: RAR-gamma; motif: RAGGTCATGACCTY 0.0287506540491371 2046 32 10 0.3125 0.00488758553274682
TF TF:M00115_1 Factor: Tax/CREB; motif: RTGACGCATAYCCCC; match class: 1 0.0295179362234322 2897 7 5 0.714285714285714 0.00172592336900242
TF TF:M11781 Factor: RXR-beta; motif: RRGGTCGTGACCYY 0.0295782313258807 261 88 6 0.0681818181818182 0.0229885057471264
TF TF:M01043_1 Factor: CSX; motif: TSYCACTTSM; match class: 1 0.0299570569465015 1199 44 9 0.204545454545455 0.00750625521267723
TF TF:M03833 Factor: NKX3A; motif: NCACTTANTYN 0.0299989888269657 895 47 8 0.170212765957447 0.00893854748603352
TF TF:M11674_1 Factor: IRF-3; motif: GCNGTTTCCWGGAAACNGAAAC; match class: 1 0.0300715368535953 1663 121 21 0.173553719008264 0.0126277811184606
TF TF:M03966_1 Factor: ELF1; motif: AACCCGGAAGTR; match class: 1 0.0301181196610244 1577 136 22 0.161764705882353 0.0139505389980977
TF TF:M01425_1 Factor: HNF-1beta; motif: NNNNGTTAACTAGNNNT; match class: 1 0.0301879956119913 1737 140 24 0.171428571428571 0.0138169257340242
TF TF:M04632_1 Factor: SREBP-1; motif: NNNGTGGGGTGAN; match class: 1 0.0301879956119913 683 35 6 0.171428571428571 0.00878477306002928
TF TF:M01224_1 Factor: P50:RELA-P65; motif: GGANTTYCCCWN; match class: 1 0.0301879956119913 236 134 7 0.0522388059701493 0.0296610169491525
TF TF:M11588 Factor: FOXK1; motif: NWYGTAAAYAR 0.030285838678308 5352 104 43 0.413461538461538 0.00803437967115097
TF TF:M04421 Factor: OTX2; motif: NTAATCCN 0.0306834404712583 568 8 3 0.375 0.00528169014084507
TF TF:M07298 Factor: Msx-1; motif: AHAWWTSMYYCAATTAN 0.0306834404712583 1938 112 22 0.196428571428571 0.0113519091847265
TF TF:M09663 Factor: STAT1; motif: YCMTTTCCNGGAAAWCNCATNN 0.032835451229704 2762 133 32 0.240601503759398 0.0115858073859522
TF TF:M03906_1 Factor: HIC2; motif: RTGCCCRNN; match class: 1 0.0329150239248246 401 24 4 0.166666666666667 0.00997506234413965
TF TF:M10541 Factor: SUHW1; motif: TCTCTCCAGTRTGAATTCTCTGAT 0.0329382686101212 7303 113 58 0.513274336283186 0.00794194166780775
TF TF:M00348 Factor: GATA-2; motif: NNWGATAASA 0.0329382686101212 2155 3 3 1 0.00139211136890951
TF TF:M03820 Factor: ER-alpha; motif: GGNNNNNNTGACCYN 0.0338179014609141 2765 91 24 0.263736263736264 0.00867992766726944
TF TF:M08557 Factor: ER71:HOXA2; motif: RCCGGAAGNNNNNNNMATTA 0.0341435970570372 221 147 7 0.0476190476190476 0.0316742081447964
TF TF:M04052 Factor: NFATc1; motif: TTTCCAYWRTGGAAA 0.0341435970570372 6663 53 29 0.547169811320755 0.00435239381659913
TF TF:M01888 Factor: Smad3; motif: NGNCAGACASNNN 0.0348172747403059 4104 60 23 0.383333333333333 0.00560428849902534
TF TF:M04756_1 Factor: sin3A; motif: TGTCCNNGGTGCTG; match class: 1 0.0349698076479195 7714 49 30 0.612244897959184 0.00388903292714545
TF TF:M11695_1 Factor: MEF-2D; motif: CCAWATWTRG; match class: 1 0.0358940182285735 195 23 3 0.130434782608696 0.0153846153846154
TF TF:M01168 Factor: SREBP; motif: NNNNYCACNCCANNN 0.0360516913119261 6651 6 6 1 0.0009021199819576
TF TF:M11222 Factor: CREB1; motif: NRTGAYGTCAYN 0.0367481090946958 3688 14 8 0.571428571428571 0.00216919739696312
TF TF:M00176 Factor: AP-4; motif: CWCAGCTGGN 0.0367481090946958 2528 146 32 0.219178082191781 0.0126582278481013
TF TF:M00339_1 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS; match class: 1 0.0370687700093002 1466 69 13 0.188405797101449 0.00886766712141883
TF TF:M08453 Factor: ERF:SREBP-2; motif: NSCGGAARTCACGTGAT 0.0370687700093002 10112 74 51 0.689189189189189 0.00504351265822785
TF TF:M00776_1 Factor: SREBP; motif: VNNVTCACCCYA; match class: 1 0.037617328091013 1289 35 8 0.228571428571429 0.00620636152055857
TF TF:M09656_1 Factor: Smad2; motif: TGTCTGNCACCT; match class: 1 0.0382378269307409 1268 28 7 0.25 0.0055205047318612
TF TF:M11445_1 Factor: Elf-1; motif: NANCAGGAAGTR; match class: 1 0.0383819839847348 83 55 3 0.0545454545454545 0.036144578313253
TF TF:M11757 Factor: HNF-4alpha; motif: RRGTCCAAAGGTCAN 0.0386030257832275 1947 66 15 0.227272727272727 0.00770416024653313
TF TF:M04145 Factor: TEAD4; motif: NRCATTCCWN 0.0386030257832275 1456 8 4 0.5 0.00274725274725275
TF TF:M10079_1 Factor: STAT1; motif: NCCNTTTCCNGGAAANCNC; match class: 1 0.038617948351474 1164 141 18 0.127659574468085 0.0154639175257732
TF TF:M00459_1 Factor: STAT5B; motif: NAWTTCYNGGAAWTN; match class: 1 0.0386202221735095 1896 147 26 0.17687074829932 0.0137130801687764
TF TF:M11561_1 Factor: FKHL14; motif: RNAAAYAAACAN; match class: 1 0.0386202221735095 440 77 7 0.0909090909090909 0.0159090909090909
TF TF:M07417_1 Factor: Elf-1; motif: NNCAGGAAGNNN; match class: 1 0.0389448562996311 102 98 4 0.0408163265306122 0.0392156862745098
TF TF:M01146 Factor: DMRT1; motif: TTGMTACAWTGTTKC 0.0389448562996311 737 60 8 0.133333333333333 0.0108548168249661
TF TF:M07421 Factor: HOXC-8; motif: GAATWAYARN 0.0389448562996311 1504 4 3 0.75 0.00199468085106383
TF TF:M03545 Factor: c-Rel; motif: NGGGAATYTCCN 0.0389451928706595 5530 91 39 0.428571428571429 0.00705244122965642
TF TF:M09589_1 Factor: AR; motif: NGNACANNNTGTTCYNN; match class: 1 0.0391351971269455 1159 48 9 0.1875 0.00776531492666091
TF TF:M09663_1 Factor: STAT1; motif: YCMTTTCCNGGAAAWCNCATNN; match class: 1 0.0393502648569104 554 62 7 0.112903225806452 0.0126353790613718
TF TF:M07417 Factor: Elf-1; motif: NNCAGGAAGNNN 0.0395132243156735 1774 45 11 0.244444444444444 0.00620067643742954
TF TF:M11360 Factor: c-MAF; motif: NTGCTGACNNNGCR 0.0395132243156735 221 46 4 0.0869565217391304 0.0180995475113122
TF TF:M10586 Factor: Barx-2; motif: NWWAAYCATTAN 0.0395418143256883 1016 26 6 0.230769230769231 0.00590551181102362
TF TF:M04415 Factor: NKX6-1; motif: NTMATTAA 0.0397387784820483 1846 136 24 0.176470588235294 0.0130010834236186
TF TF:M00291_1 Factor: Freac-3; motif: NNNNNGTAAATAAACA; match class: 1 0.0397387784820483 1096 115 15 0.130434782608696 0.0136861313868613
TF TF:M00195 Factor: Oct-1; motif: NNNNATGCAAATNAN 0.0398713414689121 3659 104 32 0.307692307692308 0.00874555889587319
TF TF:M03906 Factor: HIC2; motif: RTGCCCRNN 0.0403049981798118 3458 101 30 0.297029702970297 0.00867553499132447
TF TF:M00175 Factor: AP-4; motif: VDCAGCTGNN 0.0403049981798118 2471 109 25 0.229357798165138 0.0101173613921489
TF TF:M01870_1 Factor: C-ets-1; motif: AGGAAGN; match class: 1 0.0403562065383762 1496 69 13 0.188405797101449 0.00868983957219251
TF TF:M03579_1 Factor: PEA3; motif: AGGAAGT; match class: 1 0.0403562065383762 1496 69 13 0.188405797101449 0.00868983957219251
TF TF:M07382_1 Factor: Fli-1; motif: MGGAAGT; match class: 1 0.0403562065383762 1496 69 13 0.188405797101449 0.00868983957219251
TF TF:M02278_1 Factor: SPI1; motif: AGGAAGT; match class: 1 0.0403562065383762 1496 69 13 0.188405797101449 0.00868983957219251
TF TF:M04681 Factor: JunD; motif: RTGACGTCA 0.0408354303917914 6003 101 45 0.445544554455446 0.00749625187406297
TF TF:M04514_1 Factor: CPEB1; motif: AATAAAAA; match class: 1 0.0408354303917914 1113 114 15 0.131578947368421 0.0134770889487871
TF TF:M01971 Factor: LHX3b; motif: AATTAATTWN 0.0409863102498874 862 13 4 0.307692307692308 0.00464037122969838
TF TF:M00956 Factor: AR; motif: NNNNNNRGNACRNNGTGTTCTNNNNNN 0.0412739835511688 2717 54 16 0.296296296296296 0.00588884799411115
TF TF:M04706_1 Factor: RelA; motif: GGGRAWTYC; match class: 1 0.0416976587952829 344 129 8 0.062015503875969 0.0232558139534884
TF TF:M11795_1 Factor: NR1B1; motif: NRGGTCANNRGGTCAN; match class: 1 0.0416976587952829 2272 13 6 0.461538461538462 0.00264084507042254
TF TF:M07432_1 Factor: Sox-2; motif: NNNNNAACAAWGN; match class: 1 0.0430025042547768 84 125 4 0.032 0.0476190476190476
TF TF:M00260 Factor: HLF; motif: GTTACRYAAT 0.0435641361565493 2816 11 6 0.545454545454545 0.00213068181818182
TF TF:M07355 Factor: GR; motif: AGAACAN 0.0435732366785171 5862 63 30 0.476190476190476 0.00511770726714432
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 0.0435732366785171 1657 144 23 0.159722222222222 0.0138805069402535
TF TF:M00476 Factor: FOXO4; motif: NNGTTGTTTACNTN 0.0444953510602446 2740 116 28 0.241379310344828 0.0102189781021898
TF TF:M02116_1 Factor: Sox-10; motif: NACAAWG; match class: 1 0.0449852494624922 8039 95 53 0.557894736842105 0.00659285980843388
TF TF:M04610 Factor: CDP; motif: NNNNWGWYMAATR 0.0451982795941267 4564 10 7 0.7 0.00153374233128834
TF TF:M11554_1 Factor: HFH2; motif: NYWAYRTAAACA; match class: 1 0.0452537439593464 789 115 12 0.104347826086957 0.0152091254752852
TF TF:M03823_1 Factor: FOXO1A; motif: AAACAA; match class: 1 0.0452537439593464 9098 125 74 0.592 0.00813365574851616
TF TF:M03854_1 Factor: SRY; motif: TTGTTT; match class: 1 0.0452537439593464 9098 125 74 0.592 0.00813365574851616
TF TF:M09625 Factor: GR; motif: RGNACANKNTGTNCY 0.0452537439593464 9274 50 34 0.68 0.00366616346775933
TF TF:M09625_1 Factor: GR; motif: RGNACANKNTGTNCY; match class: 1 0.0452537439593464 4205 57 22 0.385964912280702 0.00523186682520809
TF TF:M00422 Factor: FOXJ2; motif: NNNWAAAYAAAYANNNNN 0.0453236656974447 2538 131 29 0.221374045801527 0.0114263199369582
TF TF:M08895 Factor: PITX; motif: TAATCCCN 0.0455007593870727 854 32 6 0.1875 0.00702576112412178
TF TF:M10025_1 Factor: p73; motif: NNRCAWGYCCARRCWTGYC; match class: 1 0.0458272263219922 1411 130 19 0.146153846153846 0.0134656272147413
TF TF:M00776 Factor: SREBP; motif: VNNVTCACCCYA 0.0463767120051906 6530 39 22 0.564102564102564 0.00336906584992343
TF TF:M08359 Factor: HOXD12:Elk-1; motif: NRNCGGAAGTCGTAAAN 0.046552265250726 6152 84 39 0.464285714285714 0.00633940182054616
TF TF:M10890 Factor: PRX-2; motif: CTAATTAN 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M10969 Factor: Hesx1; motif: CYAATTAN 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M01836 Factor: GR; motif: CNNNNTGTYCTNN 0.046552265250726 5942 55 27 0.490909090909091 0.00454392460451027
TF TF:M10878 Factor: alx3; motif: CYAATTAN 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M04416 Factor: NKX6-2; motif: NYMATTAA 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M10905 Factor: SHOX; motif: YYAATTAN 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M10975 Factor: LHX9; motif: CYAATTAR 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M10955 Factor: isx; motif: CTAATTAR 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M10875 Factor: alx3; motif: CTAATTAN 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M10979 Factor: LHX9; motif: CYAATTAN 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M07994 Factor: LBX1; motif: NTAATTAG 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M10986 Factor: LHX8; motif: CTAATTAN 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M04381 Factor: ISX; motif: NYAATTAN 0.046552265250726 990 131 15 0.114503816793893 0.0151515151515152
TF TF:M01012_1 Factor: HNF3; motif: NNNNNTRTTTRYTYWNKN; match class: 1 0.0466282112547924 257 104 6 0.0576923076923077 0.0233463035019455
TF TF:M07429 Factor: SMAD3; motif: CAGACAS 0.0466282112547924 6273 10 8 0.8 0.00127530687071577
TF TF:M01151 Factor: DMRT7; motif: TTGTTACAWTKTKG 0.0470030876477096 1009 80 11 0.1375 0.0109018830525273
TF TF:M04619 Factor: MTF-1; motif: CCGNGTGCAV 0.0476162603959554 1167 146 18 0.123287671232877 0.0154241645244216
TF TF:M09808 Factor: KLF4; motif: MCACACCCTNN 0.0476162603959554 3799 9 6 0.666666666666667 0.00157936299026059
TF TF:M11814 Factor: T3R-beta; motif: NRGGTCAAAGGTCRN 0.0478223477587482 13972 36 33 0.916666666666667 0.0023618665903235
TF TF:M02112 Factor: OC-2; motif: TCAATA 0.0491641980638464 7568 112 58 0.517857142857143 0.00766384778012685
TF TF:M11633_1 Factor: Sox-10; motif: AACAATGGNCCATTGTT; match class: 1 0.0491650472581208 3248 91 26 0.285714285714286 0.00800492610837438
TF TF:M01220 Factor: STAT3:STAT3; motif: TTKMCGGGAAMTSC 0.0493150198539534 1026 103 13 0.12621359223301 0.0126705653021442
TF TF:M11335_1 Factor: ATF-4; motif: GGATGACGTCATCC; match class: 1 0.0493208845444414 2207 14 6 0.428571428571429 0.00271862256456729
TF TF:M07038 Factor: DBP; motif: TTRCATAANN 0.0495723280036831 4324 102 35 0.343137254901961 0.00809435707678076
TF TF:M05445_1 Factor: GATA-5; motif: TTAMCAR; match class: 1 0.0495723280036831 414 89 7 0.0786516853932584 0.0169082125603865
TF TF:M12333_1 Factor: ZBTB20; motif: NNAAYGTATRKN; match class: 1 0.0495723280036831 360 130 8 0.0615384615384615 0.0222222222222222
TF TF:M12068 Factor: ZNF32; motif: NNGTAACNYGAYACC 0.0495723280036831 567 102 9 0.0882352941176471 0.0158730158730159
TF TF:M04378_1 Factor: IRX5; motif: NWACAYRACAWN; match class: 1 0.0495723280036831 592 47 6 0.127659574468085 0.0101351351351351
TF TF:M11386 Factor: elf5; motif: AANNAGGAAGTR 0.0495723280036831 678 55 7 0.127272727272727 0.0103244837758112
WP WP:WP619 Type II interferon signaling (IFNG) 2.06412026232745e-15 37 104 14 0.134615384615385 0.378378378378378
WP WP:WP4197 The human immune response to tuberculosis 1.57105525301848e-14 23 35 9 0.257142857142857 0.391304347826087
WP WP:WP4880 Host-pathogen interaction of human corona viruses - Interferon induction 8.91301826250973e-09 33 98 9 0.0918367346938776 0.272727272727273
WP WP:WP183 Proteasome Degradation 1.33433692276167e-08 64 126 12 0.0952380952380952 0.1875
WP WP:WP5039 SARS-CoV-2 Innate Immunity Evasion and Cell-specific immune response 5.88181784250053e-08 68 108 11 0.101851851851852 0.161764705882353
WP WP:WP4868 Type I Interferon Induction and Signaling During SARS-CoV-2 Infection 1.2923185376857e-06 29 98 7 0.0714285714285714 0.241379310344828
WP WP:WP4217 Ebola Virus Pathway on Host 6.59442153551231e-06 130 41 8 0.195121951219512 0.0615384615384615
WP WP:WP2328 Allograft Rejection 9.76718701145479e-05 88 114 9 0.0789473684210526 0.102272727272727
WP WP:WP4705 Pathways of nucleic acid metabolism and innate immune sensing 0.000189148858020953 16 73 4 0.0547945205479452 0.25
WP WP:WP4877 Host-pathogen interaction of human corona viruses - MAPK signaling 0.000260524693736921 36 35 4 0.114285714285714 0.111111111111111
WP WP:WP4341 Non-genomic actions of 1,25 dihydroxyvitamin D3 0.000455891153228852 70 70 6 0.0857142857142857 0.0857142857142857
WP WP:WP4912 SARS coronavirus and innate immunity 0.000455891153228852 31 98 5 0.0510204081632653 0.161290322580645
WP WP:WP3865 Novel intracellular components of RIG-I-like receptor (RLR) pathway 0.000495630431412718 61 122 7 0.0573770491803279 0.114754098360656
WP WP:WP2113 Type III interferon signaling 0.00216886098411347 10 98 3 0.0306122448979592 0.3
WP WP:WP4655 Cytosolic DNA-sensing pathway 0.00331391979750997 74 99 6 0.0606060606060606 0.0810810810810811
WP WP:WP5038 SARS-CoV-2 mitochondrial interactions 0.0280383531918494 32 73 3 0.0410958904109589 0.09375
WP WP:WP75 Toll-like Receptor Signaling Pathway 0.0353201482168952 104 114 6 0.0526315789473684 0.0576923076923077
WP WP:WP1449 Regulation of toll-like receptor signaling pathway 0.041217030145824 145 114 7 0.0614035087719298 0.0482758620689655

pS05 transcription factor target enrichment of top program genes

TF enrichment of pS05
TFs corrosponding to activation of pS05. (Left) pearson correlation of TF expression and gene expression program activatity in Stromal cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.